Literatures

Primary Site >> Colorectal Cancer

Gene >> FHIT

1.
Journal:	Cancer Res. 1996 Mar 1;56(5):978-83.
Title:	Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
Author:	Kastury, K\|Baffa, R\|Druck, T\|Ohta, M\|Cotticelli, M G\|Inoue, H\|Negrini, M\|Rugge, M\|Huang, D\|Croce, C M\|Palazzo, J\|Huebner, K
PMID:	8640789

2.
Journal:	Cancer Res. 1996 Jul 1;56(13):2936-9.
Title:	Evaluation of the FHIT gene in colorectal cancers.
Author:	Thiagalingam, S\|Lisitsyn, N A\|Hamaguchi, M\|Wigler, M H\|Willson, J K\|Markowitz, S D\|Leach, F S\|Kinzler, K W\|Vogelstein, B
PMID:	8674044

3.
Journal:	Cell. 1996 Feb 23;84(4):587-97.
Title:	The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers.
Author:	Ohta, M\|Inoue, H\|Cotticelli, M G\|Kastury, K\|Baffa, R\|Palazzo, J\|Siprashvili, Z\|Mori, M\|McCue, P\|Druck, T\|Croce, C M\|Huebner, K
PMID:	8598045

4.
Journal:	Hum Mol Genet. 1997 Feb;6(2):193-203.
Title:	Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B.
Author:	Boldog, F\|Gemmill, R M\|West, J\|Robinson, M\|Robinson, L\|Li, E\|Roche, J\|Todd, S\|Waggoner, B\|Lundstrom, R\|Jacobson, J\|Mullokandov, M R\|Klinger, H\|Drabkin, H A
PMID:	9063739

5.
Journal:	Jpn J Cancer Res. 1997 Apr;88(4):385-8.
Title:	Alternative splicing of the FHIT gene in colorectal cancers.
Author:	Hibi, K\|Taguchi, M\|Nakamura, H\|Hirai, A\|Fujikake, Y\|Matsui, T\|Kasai, Y\|Akiyama, S\|Ito, K\|Takagi, H
PMID:	9197530

6.
Journal:	Br J Cancer. 1999 Nov;81(5):874-80.
Title:	HIT family genes: FHIT but not PKCI-1/HINT produces altered transcripts in colorectal cancer.
Author:	Elnatan, J\|Murphy, D\|Goh, H S\|Smith, D R
PMID:	10555761

7.
Journal:	Biochem Biophys Res Commun. 2000 Nov 11;278(1):205-10.
Title:	Frequent altered expression of fragile histidine triad protein in human colorectal adenomas.
Author:	Morikawa, H\|Nakagawa, Y\|Hashimoto, K\|Niki, M\|Egashira, Y\|Hirata, I\|Katsu, K\|Akao, Y
PMID:	11071873

8.
Journal:	Hunan Yi Ke Da Xue Xue Bao. 2000 Aug 28;25(4):331-3.
Title:	[Abnormal expression of the FHIT gene in human primary gastrointestinal cancers].
Author:	Duan, X M\|Zhang, G Y\|Wu, E S
PMID:	12205991

9.
Journal:	Scand J Gastroenterol. 2000 Jun;35(6):637-41.
Title:	Clinicopathologic features and FHIT gene expression in sporadic colorectal adenocarcinomas.
Author:	Luceri, C\|Guglielmi, F\|De Filippo, C\|Caderni, G\|Mini, E\|Biggeri, A\|Napoli, C\|Tonelli, F\|Cianchi, F\|Dolara, P
PMID:	10912665

10.
Journal:	Cancer Res. 2000 Jan 1;60(1):18-21.
Title:	Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions.
Author:	Hao, X P\|Willis, J E\|Pretlow, T G\|Rao, J S\|MacLennan, G T\|Talbot, I C\|Pretlow, T P
PMID:	10646844

11.
Journal:	Cancer Res. 2001 Oct 15;61(20):7379-82.
Title:	Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Author:	Mori, M\|Mimori, K\|Masuda, T\|Yoshinaga, K\|Yamashita, K\|Matsuyama, A\|Inoue, H
PMID:	11606365

12.
Journal:	Pol J Pathol. 2001;52(3):125-32.
Title:	Fhit protein expression in hereditary and sporadic colorectal cancers.
Author:	Hadaczek, P\|Debniak, T\|Kurzawski, G\|Jakubowska, A\|Huzarski, T\|Huebner, K\|Lubinski, J
PMID:	11769399

13.
Journal:	Zhonghua Yi Xue Za Zhi. 2001 Mar 25;81(6):336-9.
Title:	[Loss of heterozygosity on chromosome 3 in sporadic colorectal carcinoma].
Author:	Peng, Z\|Ling, Y\|Bai, S
PMID:	11798895

14.
Journal:	Nihon Geka Gakkai Zasshi. 2002 Jun;103(6):468-71.
Title:	[Recent advances in the diagnosis and treatment of colorectal cancers].
Author:	Mimori, Koshi\|Mori, Masaki
PMID:	12094697

15.
Journal:	Anticancer Res. 2002 Nov-Dec;22(6A):3205-12.
Title:	Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients.
Author:	Petursdottir, Thorgunnur Eyfjord\|Hafsteinsdottir, Sigridur H\|Jonasson, Jon G\|Moller, Pall H\|Thorsteinsdottir, Unnur\|Huiping, Chen\|Egilsson, Valgardur\|Ingvarsson, Sigurdur
PMID:	12530066

16.
Journal:	Dig Liver Dis. 2002 Aug;34(8):553-9.
Title:	Microsatellite instability in a population of sporadic colorectal cancers: correlation between genetic and pathological profiles.
Author:	Luceri, C\|De Filippo, C\|Guglielmi, F\|Caderni, G\|Messerini, L\|Biggeri, A\|Mini, E\|Tonelli, F\|Cianchi, F\|Dolara, P
PMID:	12502211

17.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2002 Apr;31(2):124-7.
Title:	Loss of fragile histidine triad expression in colorectal carcinoma.
Author:	Zhao, Po\|Lu, Yali\|Hu, Yingchuan\|Zhong, Mei\|Li, Zhijun\|Li, Xianghong
PMID:	12419158

18.
Journal:	Int J Colorectal Dis. 2002 Nov;17(6):396-401. Epub 2002 May 29.
Title:	Deletion of the FHIT gene in human colorectal cancer is independent of high-risk HPV infection.
Author:	Yu, Hong-Gang\|Shun, Lai-Bao\|Luo, He-Sheng\|Huang, He\|Yu, Bao-Ping\|Yu, Jie-Ping\|Meier, Juris J\|Schrader, Henning\|Bastian, Andreas\|Schmitz, Frank\|Schmidt, Wolfgang E
PMID:	12355215

19.
Journal:	Br J Cancer. 2002 Aug 12;87(4):441-5.
Title:	Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma.
Author:	Andachi, H\|Yashima, K\|Koda, M\|Kawaguchi, K\|Kitamura, A\|Hosoda, A\|Kishimoto, Y\|Shiota, G\|Ito, H\|Makino, M\|Kaibara, N\|Kawasaki, H\|Murawaki, Y
PMID:	12177781

20.
Journal:	Clin Exp Metastasis. 2002;19(4):351-8.
Title:	FHIT protein expression and its relation to apoptosis, tumor histologic grade and prognosis in colorectal adenocarcinoma: an immunohistochemical and image analysis study.
Author:	Mady, Hussam H\|Melhem, Mona F
PMID:	12090476

21.
Journal:	Curr Opin Oncol. 2002 Mar;14(2):171-9.
Title:	Translational oncogenomics: toward rational therapeutic decision-making.
Author:	Rosell, Rafael\|Monzo, Mariano\|O'Brate, Aurora\|Taron, Miquel
PMID:	11880707

22.
Journal:	Oncology. 2003;64(3):275-9.
Title:	Microsatellite instability is often observed in esophageal carcinoma patients with allelic loss in the FHIT/FRA3B locus.
Author:	Mimori, Koshi\|Inoue, Hiroshi\|Shiraishi, Takeshi\|Matsuyama, Ayumi\|Mafune, Ken-ichi\|Tanaka, Yoichi\|Mori, Masaki
PMID:	12697969

23.
Journal:	Int J Mol Med. 2003 Oct;12(4):437-42.
Title:	Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
Author:	Kuwai, Toshio\|Tanaka, Shinji\|Kaio, Eijiro\|Hiyama, Toru\|Ito, Masanori\|Kitadai, Yasuhiko\|Sumii, Masaharu\|Yoshihara, Masaharu\|Haruma, Ken\|Chayama, Kazuaki
PMID:	12964015

24.
Journal:	Clin Cancer Res. 2004 Mar 1;10(5):1698-705.
Title:	Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma.
Author:	Lee, Hye Seung\|Chang, Mee Soo\|Yang, Han-Kwang\|Lee, Byung Lan\|Kim, Woo Ho
PMID:	15014022

25.
Journal:	Ai Zheng. 2004 Mar;23(3):310-6.
Title:	[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance].
Author:	Yao, Cheng-Cai\|Lin, Cong-Yao\|Hu, Ming-Bo
PMID:	15025965

26.
Journal:	Eur J Cancer. 2004 Jul;40(10):1581-8.
Title:	Abnormal Fhit protein expression and high frequency of microsatellite instability in sporadic colorectal cancer.
Author:	Sarli, Leopoldo\|Bottarelli, Lorena\|Azzoni, Cinzia\|Campanini, Nicoletta\|Di Cola, Gabriella\|Bader, Giovanni\|Iusco, Domenico\|Salvemini, Carlo\|Caruso, Giuseppe\|Donadei, Enrico\|Pizzi, Silvia\|D'Adda, Tiziana\|Renato, Costi\|Roncoroni, Luigi\|Bordi, Cesare
PMID:	15196543

27.
Journal:	Mod Pathol. 2005 Feb;18(2):170-8.
Title:	Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author:	Dong, Seung M\|Lee, Eui J\|Jeon, Eun S\|Park, Cheol K\|Kim, Kyoung-Mee
PMID:	15389252

28.
Journal:	Res Commun Mol Pathol Pharmacol. 2005;117-118:153-65.
Title:	Aberrant FHIT transcripts in human colorectal cancers.
Author:	Lee, Sung-Ho\|Lee, Sang-Han
PMID:	18426086

29.
Journal:	Cancer Res. 2006 Mar 1;66(5):2683-90.
Title:	FHIT is up-regulated by inflammatory stimuli and inhibits prostaglandin E2-mediated cancer progression.
Author:	Mimori, Koshi\|Ishii, Hideshi\|Nagahara, Hisashi\|Sudo, Tomoya\|Yamashita, Keishi\|Inoue, Hiroshi\|Barnard, Graham F\|Mori, Masaki
PMID:	16510588

30.
Journal:	Surg Oncol. 2006 Dec;15(4):223-33. Epub 2007 Mar 26.
Title:	Down-regulation of FHIT inhibits apoptosis of colorectal cancer: mechanism and clinical implication.
Author:	Cao, Jie\|Li, Wanglin\|Xie, Jie\|Du, Hong\|Tang, Weibiao\|Wang, Hui\|Chen, Xiwen\|Xiao, Wanqing\|Li, Yuyuan
PMID:	17382535

31.
Journal:	Exp Cell Res. 2006 Aug 1;312(13):2433-42. Epub 2006 Apr 25.
Title:	Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines.
Author:	Nakagawa, Yoshihito\|Akao, Yukihiro
PMID:	16733051

32.
Journal:	Surg Oncol. 2006 Aug;15(2):97-106.
Title:	Loss of p27 expression and microsatellite instability in sporadic colorectal cancer.
Author:	Sarli, Leopoldo\|Bottarelli, Lorena\|Azzoni, Cinzia\|Campanini, Nicoletta\|Di Cola, Gabriella\|Barilli, Angela Luciana\|Marchesi, Federico\|Mazzeo, Antonio\|Salvemini, Carlo\|Morari, Silvia\|Di Mauro, Davide\|Donadei, Enrico\|Necchi, Fransesca\|Roncoroni, Luigi\|Bordi,
PMID:	17123889

33.
Journal:	Int J Colorectal Dis. 2007 Feb;22(2):115-26.
Title:	Distinct molecular patterns based on proximal and distal sporadic colorectal cancer: arguments for different mechanisms in the tumorigenesis.
Author:	Azzoni, Cinzia\|Bottarelli, Lorena\|Campanini, Nicoletta\|Di Cola, Gabriella\|Bader, Giovanni\|Mazzeo, Antonio\|Salvemini, Carlo\|Morari, Silvia\|Di Mauro, Davide\|Donadei, Enrico\|Roncoroni, Luigi\|Bordi, Cesare\|Sarli, Leopoldo
PMID:	17021745

34.
Journal:	World J Gastroenterol. 2007 Feb 21;13(7):1018-26.
Title:	Decreased fragile histidine triad expression in colorectal cancer and its association with apoptosis inhibition.
Author:	Cao, Jie\|Chen, Xiao-Ping\|Li, Wang-Lin\|Xia, Jie\|Du, Hong\|Tang, Wei-Biao\|Wang, Hui\|Chen, Xi-Wen\|Xiao, Huan-Qing\|Li, Yu-Yuan
PMID:	17373735

35.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Mar;10(2):177-81.
Title:	[Fragile histidine triad protein expression and correlation with apoptosis in rectal carcinoma].
Author:	Cao, Jie\|Xia, Jie\|Wang, Hui\|DU, Hong\|Li, Wang-Lin
PMID:	17380463

36.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1):39-42.
Title:	FHIT oncosuppressor gene expression profile in human anal cancers.
Author:	Zucchini, C\|Concu, M\|Martini, F\|Morelli, C\|Salfi, N\|Carinci, P\|Tognon, M\|Caramelli, E
PMID:	17393360

37.
Journal:	Carcinogenesis. 2007 Sep;28(9):1851-8. Epub 2007 Aug 11.
Title:	Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns.
Author:	Lea, I A\|Jackson, M A\|Li, X\|Bailey, S\|Peddada, S D\|Dunnick, J K
PMID:	17693665

38.
Journal:	Front Med China. 2007 May;1(2):147-56.
Title:	Absence of FHIT expression is associated with apoptosis inhibition in colorectal cancer.
Author:	Cao, Jie\|Chen, Xiaoping\|Li, Wanglin\|Xia, Jie\|Du, Hong\|Tang, Weibiao\|Chen, Shanming\|Wang, Hui\|Chen, Xiwen\|Xiao, Huanqing\|Li, Yuyuan
PMID:	24557667

39.
Journal:	Oncol Rep. 2008 Jan;19(1):41-7.
Title:	Fhit, Mlh1, P53 and phenotypic expression in the early stage of colorectal neoplasms.
Author:	Yasugi, Akiko\|Yashima, Kazuo\|Hara, Akihito\|Koda, Masaharu\|Kawaguchi, Koichiro\|Harada, Kenichi\|Andachi, Hironobu\|Murawaki, Yoshikazu
PMID:	18097574

40.
Journal:	Ann Surg Oncol. 2008 May;15(5):1429-39.
Title:	Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features.
Author:	Leopoldo, Sarli\|Lorena, Bottarelli\|Cinzia, Azzoni\|Gabriella, Di Cola\|Angela Luciana, Barilli\|Renato, Costi\|Antonio, Mazzeo\|Carlo, Salvemini\|Cristina, Porrini\|Stefano, Cecchini\|Maurizio, Taglia\|Luigi, Roncoroni\|Cesare, Bordi
PMID:	18301950

41.
Journal:	Zhonghua Yi Xue Za Zhi. 2008 Mar 4;88(9):610-4.
Title:	[Expression of nuclear factor-kappa-B/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof].
Author:	Lu, Yang\|Liu, Lin\|Zhao, Po
PMID:	18646716

42.
Journal:	J Gastroenterol. 2009;44(10):1036-45.
Title:	Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender.
Author:	Umeto, Harue\|Yoshida, Tsutomu\|Araki, Kayo\|Yagishita, Hiroko\|Mikami, Tetuo\|Okayasu, Isao
PMID:	19590931

43.
Journal:	J Physiol Pharmacol. 2009 Oct;60 Suppl 4:63-70.
Title:	Fragile histidine triad (FHIT) gene is overexpressed in colorectal cancer.
Author:	Wierzbicki, P M\|Adrych, K\|Kartanowicz, D\|Dobrowolski, S\|Stanislawowski, M\|Chybicki, J\|Godlewski, J\|Korybalski, B\|Smoczynski, M\|Kmiec, Z
PMID:	20083853

44.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Sep;13(9):691-4.
Title:	[Impact of fragile histidine triad gene transfection on the proliferation and apoptosis of human colorectal cancer cell].
Author:	Cao, Jie\|Liang, Li-yuan\|Yang, Ping\|Qian, Yue-jun\|Wang, Hui\|Sun, Zheng\|Li, Wang-lin\|Tan, Ming-hua
PMID:	20878579

45.
Journal:	World J Gastrointest Oncol. 2012 Dec 15;4(12):250-8.
Title:	Aberrant crypt focus and fragile histidine triad protein in sporadic colorectal carcinoma.
Author:	Vaiphei, Kim\|Rangan, Aruna\|Singh, Rajinder
PMID:	23443232

46.
Journal:	Oncol Lett. 2013 Jan;5(1):173-178.
Title:	Single nucleotide polymorphism array analysis of microsatellite-stable, diploid/near-diploid colorectal carcinomas without the CpG island methylator phenotype.
Author:	Linnebacher, Michael\|Ostwald, Christiane\|Koczan, Dirk\|Salem, Tareq\|Schneider, Bjorn\|Krohn, Mathias\|Ernst, Mathias\|Prall, Friedrich
PMID:	23255915

47.
Journal:	PLoS One. 2013;8(4):e60142.
Title:	Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
Author:	Sinha, Rupal\|Hussain, Showket\|Mehrotra, Ravi\|Kumar, R Suresh\|Kumar, Kapil\|Pande, Pankaj\|Doval, Dinesh Chandra\|Basir, Seemi Farhat\|Bharadwaj, Mausumi
PMID:	23573237

48.
Journal:	J Histochem Cytochem. 2013 Sep;61(9):627-38.
Title:	Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer.
Author:	Al-Temaimi, Rabeah Abbas\|Jacob, Sindhu\|Al-Ali, Waleed\|Thomas, Diana Ann\|Al-Mulla, Fahd
PMID:	23797051

49.
Journal:	Cell Commun Signal. 2013 Aug 15;11:59.
Title:	Activation state-dependent interaction between Galphaq subunits and the Fhit tumor suppressor.
Author:	Zuo, Hao\|Chan, Grace P W\|Zhu, Jing\|Yeung, Wendy W S\|Chan, Anthony S L\|Ammer, Hermann\|Wong, Yung H
PMID:	23947369

50.
Journal:	Exp Mol Pathol. 2014 Feb;96(1):92-7.
Title:	Reduced FHIT expression is associated with tumor progression in sporadic colon adenocarcinoma.
Author:	Kapitanovic, Sanja\|Cacev, Tamara\|Loncar, Bozo\|Catela Ivkovic, Tina\|Krizanac, Simun\|Pavelic, Kresimir
PMID:	24370550

51.
Journal:	J Exp Clin Cancer Res. 2014 Aug 5;33:65.
Title:	Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.
Author:	Rengucci, Claudia\|De Maio, Giulia\|Casadei Gardini, Andrea\|Zucca, Mattia\|Scarpi, Emanuela\|Zingaretti, Chiara\|Foschi, Giovanni\|Tumedei, Maria Maddalena\|Molinari, Chiara\|Saragoni, Luca\|Puccetti, Maurizio\|Amadori, Dino\|Zoli, Wainer\|Calistri, Daniele
PMID:	25091577

52.
Journal:	Gene. 2015 Aug 1;567(1):81-6.
Title:	Differential expressions of cancer-associated genes and their regulatory miRNAs in colorectal carcinoma.
Author:	Kara, Murat\|Yumrutas, Onder\|Ozcan, Onder\|Celik, Ozgur Ilhan\|Bozgeyik, Esra\|Bozgeyik, Ibrahim\|Tasdemir, Sener
PMID:	25925209

53.
Journal:	PLoS One. 2015 Dec 17;10(12):e0144708.
Title:	Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author:	Briffa, Romina\|Um, Inhwa\|Faratian, Dana\|Zhou, Ying\|Turnbull, Arran K\|Langdon, Simon P\|Harrison, David J
PMID:	26678268

54.
Journal:	Cell Discov. 2016 Jan 5;2:15039.
Title:	A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/beta-catenin signalling pathway.
Author:	Mittag, Sonnhild\|Valenta, Tomas\|Weiske, Jorg\|Bloch, Laura\|Klingel, Susanne\|Gradl, Dietmar\|Wetzel, Franziska\|Chen, Yuan\|Petersen, Iver\|Basler, Konrad\|Huber, Otmar
PMID:	27462437

55.
Journal:	Oncol Lett. 2017 Sep;14(3):3683-3688.
Title:	Protein expression of Fragile Histidine Triad and cyclooxgenase-2 in serrated neoplasia of the colorectum.
Author:	Tamoto, Akihiro\|Yashima, Kazuo\|Hosoda, Kohei\|Yamamoto, Sohei\|Kawata, Soichiro\|Ikebuchi, Yuichiro\|Matsumoto, Kazuya\|Kawaguchi, Koichiro\|Harada, Kenichi\|Murawaki, Yoshikazu\|Isomoto, Hajime
PMID:	28927131

56.
Journal:	Oncotarget. 2017 May 10;8(42):71574-71586.
Title:	Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
Author:	Jahid, Sohail\|Sun, Jian\|Gelincik, Ozkan\|Blecua, Pedro\|Edelmann, Winfried\|Kucherlapati, Raju\|Zhou, Kathy\|Jasin, Maria\|Gumus, Zeynep H\|Lipkin, Steven M
PMID:	29069730

57.
Journal:	Asia Pac J Clin Oncol. 2018 Mar 8.
Title:	Do FHIT gene alterations play a role in human solid tumors?
Author:	Silveira Zavalhia, Lisiane\|Weber Medeiros, Aline\|Oliveira Silva, Andrew\|Vial Roehe, Adriana
PMID:	29516675