Primary Site >> Colorectal Cancer

Gene >> FGFR4

Journal: Cancer. 2003 Nov 15;98(10):2245-50.
Title: Single nucleotide polymorphism in fibroblast growth factor receptor 4 at codon 388 is associated with prognosis in high-grade soft tissue sarcoma.
Author: Morimoto, Yuki|Ozaki, Toshifumi|Ouchida, Mamoru|Umehara, Norifumi|Ohata, Norihide|Yoshida, Aki|Shimizu, Kenji|Inoue, Hajime
PMID: 14601095
Journal: Oncol Rep. 2005 Aug;14(2):415-9.
Title: FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer.
Author: Spinola, Monica|Leoni, Vera Piera|Tanuma, Jun-Ichi|Pettinicchio, Angela|Frattini, Milo|Signoroni, Stefano|Agresti, Roberto|Giovanazzi, Riccardo|Pilotti, Silvana|Bertario, Lucio|Ravagnani, Fernando|Dragani, Tommaso A
PMID: 16012724
Journal: Exp Mol Pathol. 2007 Feb;82(1):53-7. Epub 2006 Nov 3.
Title: The fibroblast growth factor receptor 4 (FGFR4) Arg388 allele correlates with survival in head and neck squamous cell carcinoma.
Author: da Costa Andrade, Valeria Cristina|Parise, Orlando Jr|Hors, Cora Pereira|de Melo Martins, Poliana Cristina|Silva, Alexandre Pacheco|Garicochea, Bernardo
PMID: 17084840
Journal: Oncogene. 2008 Jan 3;27(1):85-97. Epub 2007 Jun 25.
Title: Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
Author: Desnoyers, L R|Pai, R|Ferrando, R E|Hotzel, K|Le, T|Ross, J|Carano, R|D'Souza, A|Qing, J|Mohtashemi, I|Ashkenazi, A|French, D M
PMID: 17599042
Journal: Cancer Res. 2008 Jul 1;68(13):5086-95.
Title: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
Author: Pai, Rama|Dunlap, Debra|Qing, Jing|Mohtashemi, Iman|Hotzel, Kathy|French, Dorothy M
PMID: 18593907
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G996-G1003.
Title: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes.
Author: Sinha, Jyoti|Chen, Frank|Miloh, Tamir|Burns, Robert C|Yu, Zhisheng|Shneider, Benjamin L
PMID: 18772362
Journal: Mol Cell Proteomics. 2009 Oct;8(10):2382-95.
Title: Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.
Author: Babel, Ingrid|Barderas, Rodrigo|Diaz-Uriarte, Ramon|Martinez-Torrecuadrada, Jorge Luis|Sanchez-Carbayo, Marta|Casal, J Ignacio
PMID: 19638618
Journal: Adv Exp Med Biol. 2012;728:195-213.
Title: Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities.
Author: Wu, Xinle|Li, Yang
PMID: 22396171
Journal: J Proteomics. 2012 Aug 3;75(15):4647-55.
Title: An optimized predictor panel for colorectal cancer diagnosis based on the combination of tumor-associated antigens obtained from protein and phage microarrays.
Author: Barderas, Rodrigo|Babel, Ingrid|Diaz-Uriarte, Ramon|Moreno, Victor|Suarez, Adolfo|Bonilla, Felix|Villar-Vazquez, Roi|Capella, Gabriel|Casal, J Ignacio
PMID: 22465712
Journal: Cancer Res. 2012 Nov 15;72(22):5767-77.
Title: Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis.
Author: Heinzle, Christine|Gsur, Andrea|Hunjadi, Monika|Erdem, Zeynep|Gauglhofer, Christine|Stattner, Stefan|Karner, Josef|Klimpfinger, Martin|Wrba, Friedrich|Reti, Andrea|Hegedus, Balazs|Baierl, Andreas|Grasl-Kraupp, Bettina|Holzmann, Klaus|Grusch, Michael|Berge
PMID: 22971346
Journal: PLoS One. 2013 May 16;8(5):e63695.
Title: FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer.
Author: Pelaez-Garcia, Alberto|Barderas, Rodrigo|Torres, Sofia|Hernandez-Varas, Pablo|Teixido, Joaquin|Bonilla, Felix|de Herreros, Antonio Garcia|Casal, J Ignacio
PMID: 23696849
Journal: Cancer Res. 2013 Oct 1;73(19):5926-35.
Title: FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer.
Author: Liu, Rui|Li, Jingyi|Xie, Ke|Zhang, Tao|Lei, Yunlong|Chen, Yi|Zhang, Lu|Huang, Kai|Wang, Kui|Wu, Hong|Wu, Min|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23943801
Journal: Biomarkers. 2014 Feb;19(1):81-5.
Title: Fibroblast growth factor receptor 4 as a potential prognostic and therapeutic marker in colorectal cancer.
Author: Li, Chen-Sheng|Zhang, Shu-Xiang|Liu, Hong-Jun|Shi, Yu-Long|Li, Le-Ping|Guo, Xiao-Bo|Zhang, Zhen-Hai
PMID: 24410190
Journal: Cell Death Dis. 2014 Feb 6;5:e1046.
Title: Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer.
Author: Turkington, R C|Longley, D B|Allen, W L|Stevenson, L|McLaughlin, K|Dunne, P D|Blayney, J K|Salto-Tellez, M|Van Schaeybroeck, S|Johnston, P G
PMID: 24503538
Journal: Clin Cancer Res. 2015 Apr 1;21(7):1583-90.
Title: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
Author: Bohanes, Pierre|Rankin, Cathryn J|Blanke, Charles D|Winder, Thomas|Ulrich, Cornelia M|Smalley, Stephen R|Rich, Tyvin A|Martensen, James A|Benson, Al B 3rd|Mayer, Robert J|Cripps, Christine M|Danenberg, Kathleen|Makar, Karen W|Zhang, Wu|Benedetti, Jacqueli
PMID: 25589620
Journal: Comp Biochem Physiol B Biochem Mol Biol. 2015 Aug;186:43-50.
Title: Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents.
Author: Zhuang, Lei|Bluteau, Gilles|Trueb, Beat
PMID: 25934085
Journal: Cancer Sci. 2015 Oct;106(10):1278-87.
Title: FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7.
Author: Bai, Yu-Pan|Shang, Kun|Chen, Huan|Ding, Fei|Wang, Zhen|Liang, Chen|Xu, Ye|Sun, Meng-Hong|Li, Ying-Yi
PMID: 26183471
Journal: J Exp Clin Cancer Res. 2015 Oct 1;34:108.
Title: Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer.
Author: Giordano, Guido|Febbraro, Antonio|Tomaselli, Eugenio|Sarnicola, Maria Lucia|Parcesepe, Pietro|Parente, Domenico|Forte, Nicola|Fabozzi, Alessio|Remo, Andrea|Bonetti, Andrea|Manfrin, Erminia|Ghasemi, Somayehsadat|Ceccarelli, Michele|Cerulo, Luigi|Bazzoni, F
PMID: 26427914
Journal: Oncotarget. 2016 Mar 22;7(12):13575-86.
Title: FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3beta/beta- catenin signaling cascade via FGFR4 activation.
Author: Zhao, Huakan|Lv, Fenglin|Liang, Guizhao|Huang, Xiaobin|Wu, Gang|Zhang, Wenfa|Yu, Le|Shi, Lei|Teng, Yong
PMID: 26498355
Journal: Oncotarget. 2016 Oct 25;7(43):69976-69990.
Title: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.
Author: Ahmed, Mohamed A|Selzer, Edgar|Dorr, Wolfgang|Jomrich, Gerd|Harpain, Felix|Silberhumer, Gerd R|Mullauer, Leonhard|Holzmann, Klaus|Grasl-Kraupp, Bettina|Grusch, Michael|Berger, Walter|Marian, Brigitte
PMID: 27650548
Journal: Cancer Res Treat. 2017 Jul;49(3):766-777.
Title: FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition.
Author: Cho, Sang Hee|Hong, Chang Soo|Kim, Hee Nam|Shin, Min Ho|Kim, Ka Rham|Shim, Hyun Jeong|Hwang, Jun Eul|Bae, Woo Kyun|Chung, Ik Joo
PMID: 27857023
Journal: Int J Oncol. 2017 Nov;51(5):1611-1620.
Title: Combination of FGFR4 inhibitor Blu9931 and 5-fluorouracil effects on the biological characteristics of colorectal cancer cells.
Author: Jiang, Dongbao|Li, Jingjing|Li, Jie|Wang, Min|Han, Chao|Wang, Xinru|Zhao, Chunlin|Ye, Yanwei
PMID: 29048661
Journal: J Exp Clin Cancer Res. 2018 Apr 17;37(1):84.
Title: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
Author: Mendes Oliveira, Duarte|Grillone, Katia|Mignogna, Chiara|De Falco, Valentina|Laudanna, Carmelo|Biamonte, Flavia|Locane, Rosa|Corcione, Francesco|Fabozzi, Massimiliano|Sacco, Rosario|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia
PMID: 29665843
Journal: Oncogene. 2018 Jun 8. pii: 10.1038/s41388-018-0355-4.
Title: Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression.
Author: Liu, Jian|Zhang, Zhe|Li, Xiaowei|Chen, Jie|Wang, Guodong|Tian, Zuhong|Qian, Meirui|Chen, Zhangqian|Guo, Hao|Tang, Guangbo|Huang, Wenjie|Tian, Dean|Wang, Daowen|Nie, Yongzhan|Fan, Daiming|Wu, Kaichun|Xia, Limin
PMID: 29884889