Primary Site >> Colorectal Cancer
Gene >> FGFR4
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Ref: Single nucleotide polymorphism in fibroblast growth factor receptor 4 at codon 388 is associated with prognosis in high-grade soft tissue sarcoma. PMID: 14601095 |
Ref: FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer. PMID: 16012724 |
Ref: The fibroblast growth factor receptor 4 (FGFR4) Arg388 allele correlates with survival in head and neck squamous cell carcinoma. PMID: 17084840 |
Ref: Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. PMID: 17599042 Ref: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. PMID: 18593907 Ref: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. PMID: 18772362 |
Ref: Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays. PMID: 19638618 |
Ref: Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities. PMID: 22396171 Ref: An optimized predictor panel for colorectal cancer diagnosis based on the combination of tumor-associated antigens obtained from protein and phage microarrays. PMID: 22465712 Ref: Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis. PMID: 22971346 |
Ref: FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer. PMID: 23696849 Ref: FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. PMID: 23943801 |
Ref: Fibroblast growth factor receptor 4 as a potential prognostic and therapeutic marker in colorectal cancer. PMID: 24410190 Ref: Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer. PMID: 24503538 |
Ref: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. PMID: 25589620 Ref: Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents. PMID: 25934085 Ref: FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7. PMID: 26183471 Ref: Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer. PMID: 26427914 |
Ref: FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3beta/beta- catenin signaling cascade via FGFR4 activation. PMID: 26498355 Ref: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer. PMID: 27650548 |
Ref: FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition. PMID: 27857023 Ref: Combination of FGFR4 inhibitor Blu9931 and 5-fluorouracil effects on the biological characteristics of colorectal cancer cells. PMID: 29048661 |
Ref: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene. PMID: 29665843 Ref: Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression. PMID: 29884889 |