Primary Site >> Colorectal Cancer

Gene >> FGFR3

Journal: Cancer Res. 1994 Oct 1;54(19):5206-11.
Title: Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium.
Author: Murgue, B|Tsunekawa, S|Rosenberg, I|deBeaumont, M|Podolsky, D K
PMID: 7923141
Journal: Cancer Res. 2000 Aug 1;60(15):4049-52.
Title: Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer.
Author: Jang, J H|Shin, K H|Park, Y J|Lee, R J|McKeehan, W L|Park, J G
PMID: 10945607
Journal: Cancer Res. 2001 May 1;61(9):3541-3.
Title: Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.
Author: Jang, J H|Shin, K H|Park, J G
PMID: 11325814
Journal: Oncogene. 2005 Jan 27;24(5):945-8.
Title: Reciprocal relationship in gene expression between FGFR1 and FGFR3: implication for tumorigenesis.
Author: Jang, Jun-Hyeog
PMID: 15558020
Journal: Cell Cycle. 2008 Sep 1;7(17):2674-81.
Title: Somatic oncogenic mutations, benign skin lesions and cancer progression: where to look next?
Author: Toll, Agusti|Real, Francisco X
PMID: 18728396
Journal: Br J Cancer. 2010 Mar 30;102(7):1145-56.
Title: Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration.
Author: Sonvilla, G|Allerstorfer, S|Heinzle, C|Stattner, S|Karner, J|Klimpfinger, M|Wrba, F|Fischer, H|Gauglhofer, C|Spiegl-Kreinecker, S|Grasl-Kraupp, B|Holzmann, K|Grusch, M|Berger, W|Marian, B
PMID: 20234367
Journal: Int J Oncol. 2010 Oct;37(4):829-35.
Title: The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer.
Author: Morishita, Asahiro|Gong, Jian|Nomura, Takako|Yoshida, Hirohito|Izuishi, Kunihiko|Suzuki, Yasuyuki|Kushida, Yoshio|Haba, Reiji|D'Armiento, Jeanine|Masaki, Tsutomu
PMID: 20811704
Journal: Prostate. 2011 May;71(6):637-41.
Title: No evidence of FGFR3 mutations in prostate cancer.
Author: Zuiverloon, Tahlita C M|Boormans, Joost L|Trapman, Jan|van Leenders, Geert J L H|Zwarthoff, Ellen C
PMID: 20957671
Journal: Am J Pathol. 2011 Mar;178(3):1387-94.
Title: Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion.
Author: Henriksson, Maria L|Edin, Sofia|Dahlin, Anna M|Oldenborg, Per-Arne|Oberg, Ake|Van Guelpen, Bethany|Rutegard, Jorgen|Stenling, Roger|Palmqvist, Richard
PMID: 21356388
Journal: Mol Carcinog. 2015 Sep;54(9):789-799.
Title: Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.
Author: Koneczny, Inga|Schulenburg, Axel|Hudec, Xenia|Knofler, Martin|Holzmann, Klaus|Piazza, Gary|Reynolds, Robert|Valent, Peter|Marian, Brigitte
PMID: 24619956
Journal: Biochem Biophys Res Commun. 2015 Feb 27;458(1):52-6.
Title: Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.
Author: Kogita, Akihiro|Yoshioka, Yasumasa|Sakai, Kazuko|Togashi, Yosuke|Sogabe, Shunsuke|Nakai, Takuya|Okuno, Kiyotaka|Nishio, Kazuto
PMID: 25623536
Journal: Am J Cancer Res. 2014 Dec 15;5(1):72-86. eCollection 2015.
Title: Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer.
Author: Lee, Choong-Kun|Lee, Myung Eun|Lee, Won Suk|Kim, Jeong Min|Park, Kyu Hyun|Kim, Tae Soo|Lee, Kang Young|Ahn, Joong Bae|Chung, Hyun Cheol|Rha, Sun Young
PMID: 25628921
Journal: Oncotarget. 2015 Sep 8;6(26):22799-811.
Title: Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3.
Author: Zhang, Baolai|Dong, Shuhong|Zhu, Ruiming|Hu, Chunyan|Hou, Jing|Li, Yan|Zhao, Qian|Shao, Xue|Bu, Qian|Li, Hongyu|Wu, Yongjie|Cen, Xiaobo|Zhao, Yinglan
PMID: 26078354
Journal: J Hematol Oncol. 2015 Oct 24;8:119.
Title: Complexity of FGFR signalling in metastatic urothelial cancer.
Author: Rodriguez-Vida, Alejo|Saggese, Matilde|Hughes, Simon|Rudman, Sarah|Chowdhury, Simon|Smith, Neil R|Lawrence, Peter|Rooney, Claire|Dougherty, Brian|Landers, Donal|Kilgour, Elaine|Arkenau, Hendrik-Tobias
PMID: 26497743
Journal: Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title: Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author: Crumley, Suzanne M|Pepper, Kristi L|Phan, Alexandria T|Olsen, Randall J|Schwartz, Mary R|Portier, Bryce P
PMID: 26536055
Journal: Mol Cancer. 2016 Oct 18;15(1):63.
Title: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author: Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke
PMID: 27756406
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author: Pfarr, Nicole|Penzel, Roland|Klauschen, Frederick|Heim, Daniel|Brandt, Regine|Kazdal, Daniel|Jesinghaus, Moritz|Herpel, Esther|Schirmacher, Peter|Warth, Arne|Weichert, Wilko|Endris, Volker|Stenzinger, Albrecht
PMID: 27218826
Journal: Transl Oncol. 2017 Jun;10(3):332-339.
Title: Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis.
Author: Erdem, Zeynep N|Schwarz, Stefanie|Drev, Daniel|Heinzle, Christine|Reti, Andrea|Heffeter, Petra|Hudec, Xenia|Holzmann, Klaus|Grasl-Kraupp, Bettina|Berger, Walter|Grusch, Michael|Marian, Brigitte
PMID: 28340475
Journal: J Cell Biochem. 2017 Dec;118(12):4548-4557.
Title: lncRNA CCAT1 Promotes Glioma Tumorigenesis by Sponging miR-181b.
Author: Cui, Bingzhou|Li, Baoshan|Liu, Qi|Cui, Youqiang
PMID: 28475287
Journal: Br J Cancer. 2017 Jun 27;117(1):136-143.
Title: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
Author: Chakrabarty, Sanjiban|Varghese, Vinay Koshy|Sahu, Pranoy|Jayaram, Pradyumna|Shivakumar, Bhadravathi M|Pai, Cannanore Ganesh|Satyamoorthy, Kapaettu
PMID: 28524162
Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K
PMID: 28675510
Journal: Ann Oncol. 2017 Dec 1;28(12):3083-3091.
Title: The antibody-drug conjugate target landscape across a broad range of tumour types.
Author: Moek, K L|de Groot, D J A|de Vries, E G E|Fehrmann, R S N
PMID: 29045509
Journal: J Exp Clin Cancer Res. 2018 Apr 17;37(1):84.
Title: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
Author: Mendes Oliveira, Duarte|Grillone, Katia|Mignogna, Chiara|De Falco, Valentina|Laudanna, Carmelo|Biamonte, Flavia|Locane, Rosa|Corcione, Francesco|Fabozzi, Massimiliano|Sacco, Rosario|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia
PMID: 29665843
Journal: Oncotarget. 2018 Apr 27;9(32):22749-22768.
Title: Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
Author: Oliveira, Duarte Mendes|Mirante, Teresa|Mignogna, Chiara|Scrima, Marianna|Migliozzi, Simona|Rocco, Gaetano|Franco, Renato|Corcione, Francesco|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia
PMID: 29854313
Journal: Oncotarget. 2018 Aug 14;9(63):32204-32218.
Title: FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis.
Author: Fromme, Julia Elisabeth|Schmitz, Katja|Wachter, Astrid|Grzelinski, Marius|Zielinski, Dirk|Koppel, Christina|Conradi, Lena-Christin|Homayounfar, Kia|Hugo, Tabea|Hugo, Sara|Lukat, Laura|Ruschoff, Josef|Strobel, Philipp|Ghadimi, Michael|Beissbarth, Tim|Reute
PMID: 30181810
Journal: Pathologe. 2018 Sep 28. pii: 10.1007/s00292-018-0504-0.
Title: [FGFR3 overexpression is a relevant alteration in colorectal cancer].
Author: Fromme, J E|Schildhaus, H-U
PMID: 30267148
Journal: J Cancer Res Clin Oncol. 2018 Oct 1. pii: 10.1007/s00432-018-2757-7.
Title: FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer.
Author: Harpain, Felix|Ahmed, Mohamed A|Hudec, Xenia|Timelthaler, Gerald|Jomrich, Gerd|Mullauer, Leonhard|Selzer, Edgar|Dorr, Wolfgang|Bergmann, Michael|Holzmann, Klaus|Grasl-Kraupp, Bettina|Grusch, Michael|Berger, Walter|Marian, Brigitte|Silberhumer, Gerd R
PMID: 30276721