Primary Site >> Colorectal Cancer
Gene >> FGFR3
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Ref: Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium. PMID: 7923141 |
Ref: Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer. PMID: 10945607 |
Ref: Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers. PMID: 11325814 |
Ref: Reciprocal relationship in gene expression between FGFR1 and FGFR3: implication for tumorigenesis. PMID: 15558020 |
Ref: Somatic oncogenic mutations, benign skin lesions and cancer progression: where to look next? PMID: 18728396 |
Ref: Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration. PMID: 20234367 Ref: The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer. PMID: 20811704 |
Ref: No evidence of FGFR3 mutations in prostate cancer. PMID: 20957671 Ref: Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion. PMID: 21356388 |
Ref: Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. PMID: 24619956 Ref: Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis. PMID: 25623536 Ref: Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer. PMID: 25628921 Ref: Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3. PMID: 26078354 Ref: Complexity of FGFR signalling in metastatic urothelial cancer. PMID: 26497743 |
Ref: Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas. PMID: 26536055 Ref: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases. PMID: 27218826 Ref: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing. PMID: 27568332 Ref: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing. PMID: 27756406 |
Ref: Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis. PMID: 28340475 Ref: lncRNA CCAT1 Promotes Glioma Tumorigenesis by Sponging miR-181b. PMID: 28475287 Ref: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. PMID: 28524162 Ref: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. PMID: 28675510 Ref: The antibody-drug conjugate target landscape across a broad range of tumour types. PMID: 29045509 |
Ref: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene. PMID: 29665843 Ref: Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing. PMID: 29854313 Ref: FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis. PMID: 30181810 Ref: [FGFR3 overexpression is a relevant alteration in colorectal cancer]. PMID: 30267148 Ref: FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer. PMID: 30276721 |