Primary Site >> Colorectal Cancer
Gene >> FGFR2
| 1. | |||||||||||
| Journal: | Cancer Res. 1994 Oct 1;54(19):5206-11. | ||||||||||
| Title: | Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium. | ||||||||||
| Author: | Murgue, B|Tsunekawa, S|Rosenberg, I|deBeaumont, M|Podolsky, D K | ||||||||||
| PMID: | 7923141 | ||||||||||
| 2. | |||||||||||
| Journal: | Pathol Int. 2000 May;50(5):363-72. | ||||||||||
| Title: | Overexpression of keratinocyte growth factor in cancer cells and enterochromaffin cells in human colorectal cancer. | ||||||||||
| Author: | Watanabe, M|Ishiwata, T|Nishigai, K|Moriyama, Y|Asano, G | ||||||||||
| PMID: | 10849325 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2001 May 1;61(9):3541-3. | ||||||||||
| Title: | Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers. | ||||||||||
| Author: | Jang, J H|Shin, K H|Park, J G | ||||||||||
| PMID: | 11325814 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem J. 2001 Oct 1;359(Pt 1):153-63. | ||||||||||
| Title: | A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor. | ||||||||||
| Author: | Ghiselli, G|Eichstetter, I|Iozzo, R V | ||||||||||
| PMID: | 11563979 | ||||||||||
| 5. | |||||||||||
| Journal: | J Nippon Med Sch. 2001 Oct;68(5):397-404. | ||||||||||
| Title: | Expression of fibroblast growth factor (FGF)-10 in human colorectal adenocarcinoma cells. | ||||||||||
| Author: | Matsuike, A|Ishiwata, T|Watanabe, M|Asano, G | ||||||||||
| PMID: | 11598623 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncol Rep. 2005 Feb;13(2):247-52. | ||||||||||
| Title: | Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer. | ||||||||||
| Author: | Yoshino, Masanori|Ishiwata, Toshiyuki|Watanabe, Masanori|Komine, Osamu|Shibuya, Tetsuo|Tokunaga, Akira|Naito, Zenya | ||||||||||
| PMID: | 15643506 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2005 Feb 1;65(3):957-66. | ||||||||||
| Title: | Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. | ||||||||||
| Author: | Roberts, W Gregory|Whalen, Pamela M|Soderstrom, Erik|Moraski, Garrett|Lyssikatos, Joseph P|Wang, Huifen-F|Cooper, Beth|Baker, Deborah A|Savage, Douglas|Dalvie, Deepak|Atherton, James A|Ralston, Sherry|Szewc, Ruby|Kath, John C|Lin, Jing|Soderstrom, Cathy|T | ||||||||||
| PMID: | 15705896 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Mol Med. 2005 Jul;16(1):181-5. | ||||||||||
| Title: | Comparative genomics on Shisa orthologs. | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 15942696 | ||||||||||
| 9. | |||||||||||
| Journal: | Breast Cancer Res Treat. 2009 Sep;117(1):151-9. | ||||||||||
| Title: | Low penetrance breast cancer predisposition SNPs are site specific. | ||||||||||
| Author: | Mcinerney, Niall|Colleran, Gabrielle|Rowan, Andrew|Walther, Axel|Barclay, Ella|Spain, Sarah|Jones, Angela M|Tuohy, Stephen|Curran, Catherine|Miller, Nicola|Kerin, Michael|Tomlinson, Ian|Sawyer, Elinor | ||||||||||
| PMID: | 19005751 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Oncol. 2009 Feb;34(2):355-60. | ||||||||||
| Title: | Keratinocyte growth factor induces vascular endothelial growth factor-A expression in colorectal cancer cells. | ||||||||||
| Author: | Narita, Kosuke|Fujii, Takenori|Ishiwata, Toshiyuki|Yamamoto, Tetsushi|Kawamoto, Yoko|Kawahara, Kiyoko|Nakazawa, Nando|Naito, Zenya | ||||||||||
| PMID: | 19148469 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Nutr Food Res. 2009 Jun;53(6):686-98. | ||||||||||
| Title: | Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins. | ||||||||||
| Author: | Gonzalez-Sarrias, Antonio|Espin, Juan-Carlos|Tomas-Barberan, Francisco A|Garcia-Conesa, Maria-Teresa | ||||||||||
| PMID: | 19437480 | ||||||||||
| 12. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2009 Nov;48(11):1002-17. | ||||||||||
| Title: | Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. | ||||||||||
| Author: | Camps, Jordi|Nguyen, Quang Tri|Padilla-Nash, Hesed M|Knutsen, Turid|McNeil, Nicole E|Wangsa, Danny|Hummon, Amanda B|Grade, Marian|Ried, Thomas|Difilippantonio, Michael J | ||||||||||
| PMID: | 19691111 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Physiol Biochem. 2011;27(5):565-74. | ||||||||||
| Title: | SKLB610: a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo. | ||||||||||
| Author: | Cao, Zhi-Xing|Zheng, Ren-Lin|Lin, Hong-Jun|Luo, Shi-Dong|Zhou, Yan|Xu, You-Zhi|Zeng, Xiu-Xiu|Wang, Zhao|Zhou, Li-Na|Mao, Yong-Qiu|Yang, Li|Wei, Yu-Quan|Yu, Luo-Ting|Yang, Sheng-Yong|Zhao, Ying-Lan | ||||||||||
| PMID: | 21691074 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Lett. 2011 Oct 28;309(2):209-19. | ||||||||||
| Title: | Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: a potential therapeutic target in colorectal cancer. | ||||||||||
| Author: | Matsuda, Yoko|Ishiwata, Toshiyuki|Yamahatsu, Kazuya|Kawahara, Kiyoko|Hagio, Masahito|Peng, Wei-Xia|Yamamoto, Tetsushi|Nakazawa, Nando|Seya, Tomoko|Ohaki, Yoshiharu|Naito, Zenya | ||||||||||
| PMID: | 21745712 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Sci. 2012 Feb;103(2):221-7. | ||||||||||
| Title: | Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells. | ||||||||||
| Author: | Furuta, Kazuyuki|Arao, Tokuzo|Sakai, Kazuko|Kimura, Hideharu|Nagai, Tomoyuki|Tamura, Daisuke|Aomatsu, Keiichi|Kudo, Kanae|Kaneda, Hiroyasu|Fujita, Yoshihiko|Matsumoto, Kazuko|Yamada, Yasuhide|Yanagihara, Kazuyoshi|Sekijima, Masaru|Nishio, Kazuto | ||||||||||
| PMID: | 22034905 | ||||||||||
| 16. | |||||||||||
| Journal: | Lab Invest. 2012 Mar;92(3):420-36. | ||||||||||
| Title: | CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells. | ||||||||||
| Author: | Chao, Celia|Carmical, J Russ|Ives, Kirk L|Wood, Thomas G|Aronson, Judith F|Gomez, Guillermo A|Djukom, Clarisse D|Hellmich, Mark R | ||||||||||
| PMID: | 22157717 | ||||||||||
| 17. | |||||||||||
| Journal: | Patholog Res Int. 2012;2012:574768. | ||||||||||
| Title: | Fibroblast growth factor receptor 2: expression, roles, and potential as a novel molecular target for colorectal cancer. | ||||||||||
| Author: | Matsuda, Yoko|Ueda, Junji|Ishiwata, Toshiyuki | ||||||||||
| PMID: | 22701813 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Res. 2012 Sep 1;72(17):4383-93. Epub 2012 Jul 2. | ||||||||||
| Title: | Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. | ||||||||||
| Author: | Dulak, Austin M|Schumacher, Steven E|van Lieshout, Jasper|Imamura, Yu|Fox, Cameron|Shim, Byoungyong|Ramos, Alex H|Saksena, Gordon|Baca, Sylvan C|Baselga, Jose|Tabernero, Josep|Barretina, Jordi|Enzinger, Peter C|Corso, Giovanni|Roviello, Franco|Lin, Lin|Ba | ||||||||||
| PMID: | 22751462 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Sep;11(9):2010-20. | ||||||||||
| Title: | Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells. | ||||||||||
| Author: | Matsuda, Yoko|Hagio, Masahito|Seya, Tomoko|Ishiwata, Toshiyuki | ||||||||||
| PMID: | 22778155 | ||||||||||
| 20. | |||||||||||
| Journal: | RNA Biol. 2013 Feb;10(2):287-300. | ||||||||||
| Title: | Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines. | ||||||||||
| Author: | Druz, Aliaksandr|Chen, Yu-Chi|Guha, Rajarshi|Betenbaugh, Michael|Martin, Scott E|Shiloach, Joseph | ||||||||||
| PMID: | 23353574 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Sep;12(9):1749-62. | ||||||||||
| Title: | S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. | ||||||||||
| Author: | Burbridge, Mike F|Bossard, Celine J|Saunier, Carine|Fejes, Imre|Bruno, Alain|Leonce, Stephane|Ferry, Gilles|Da Violante, Georges|Bouzom, Francois|Cattan, Valerie|Jacquet-Bescond, Anne|Comoglio, Paolo M|Lockhart, Brian P|Boutin, Jean A|Cordi, Alex|Ortuno, | ||||||||||
| PMID: | 23804704 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Cancer. 2014 Mar 15;134(6):1279-88. | ||||||||||
| Title: | Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. | ||||||||||
| Author: | Ji, Wei|Bian, Zehua|Yu, Yang|Yuan, Chao|Liu, Yang|Yu, Lisa|Li, Chunxiang|Zhu, Jing|Jia, Xueyuan|Guan, Rongwei|Zhang, Chunyu|Meng, Xiangning|Jin, Yan|Bai, Jing|Yu, Jingcui|Lee, Ki-Young|Sun, Wenjing|Fu, Songbin | ||||||||||
| PMID: | 24027017 | ||||||||||
| 23. | |||||||||||
| Journal: | J Clin Pathol. 2014 Dec;67(12):1056-61. | ||||||||||
| Title: | Fibroblast growth factor receptor 2 overexpression is predictive of poor prognosis in rectal cancer patients receiving neoadjuvant chemoradiotherapy. | ||||||||||
| Author: | Li, Chien-Feng|He, Hong-Lin|Wang, Jaw-Yuan|Huang, Hsuan-Ying|Wu, Ting-Fe|Hsing, Chung-Hsi|Lee, Sung-Wei|Lee, Hao-Hsien|Fang, Jui-Lung|Huang, Wen-Tsung|Chen, Shang-Hung | ||||||||||
| PMID: | 25271212 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2014 Jun 26;9(6):e98515. | ||||||||||
| Title: | FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival. | ||||||||||
| Author: | Mathur, Anjili|Ware, Christopher|Davis, Lenora|Gazdar, Adi|Pan, Bo-Sheng|Lutterbach, Bart | ||||||||||
| PMID: | 24968263 | ||||||||||
| 25. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2014 Mar 1;24(5):1380-2. | ||||||||||
| Title: | Synthesis and in vivo evaluation of N-ethylamino-2-oxo-1,2-dihydro-quinoline-3-carboxamide for inhibition of intestinal tumorigenesis in APC(Min/+) mice. | ||||||||||
| Author: | Pathuri, Gopal|Li, Qian|Mohammed, Altaf|Gali, Hariprasad|Pento, J Thomas|Rao, Chinthalapally V | ||||||||||
| PMID: | 24507628 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2014 Apr 30;5(8):2096-106. | ||||||||||
| Title: | C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2. | ||||||||||
| Author: | Hung, Ji-Shiang|Huang, John|Lin, Yo-Chuen|Huang, Miao-Juei|Lee, Po-Huang|Lai, Hong-Shiee|Liang, Jin-Tung|Huang, Min-Chuan | ||||||||||
| PMID: | 24758762 | ||||||||||
| 27. | |||||||||||
| Journal: | Tumour Biol. 2015 Jul;36(7):5641-8. | ||||||||||
| Title: | AZD-4547 exerts potent cytostatic and cytotoxic activities against fibroblast growth factor receptor (FGFR)-expressing colorectal cancer cells. | ||||||||||
| Author: | Yao, Ting-Jing|Zhu, Jin-Hai|Peng, De-Feng|Cui, Zhen|Zhang, Chao|Lu, Pei-hua | ||||||||||
| PMID: | 25691251 | ||||||||||
| 28. | |||||||||||
| Journal: | PLoS Comput Biol. 2015 Mar 20;11(3):e1004147. | ||||||||||
| Title: | Protein domain-level landscape of cancer-type-specific somatic mutations. | ||||||||||
| Author: | Yang, Fan|Petsalaki, Evangelia|Rolland, Thomas|Hill, David E|Vidal, Marc|Roth, Frederick P | ||||||||||
| PMID: | 25794154 | ||||||||||
| 29. | |||||||||||
| Journal: | Nat Commun. 2015 Apr 30;6:7002. | ||||||||||
| Title: | The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets. | ||||||||||
| Author: | Medico, Enzo|Russo, Mariangela|Picco, Gabriele|Cancelliere, Carlotta|Valtorta, Emanuele|Corti, Giorgio|Buscarino, Michela|Isella, Claudio|Lamba, Simona|Martinoglio, Barbara|Veronese, Silvio|Siena, Salvatore|Sartore-Bianchi, Andrea|Beccuti, Marco|Mottolese | ||||||||||
| PMID: | 25926053 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2015 Nov 10;6(35):38046-60. | ||||||||||
| Title: | The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells. | ||||||||||
| Author: | Liang, Yu-Chih|Lin, Wei-Cheng|Lin, Ying-Ju|Lin, Jung-Chun | ||||||||||
| PMID: | 26506517 | ||||||||||
| 31. | |||||||||||
| Journal: | BMC Cancer. 2015 Dec 16;15:946. | ||||||||||
| Title: | In vitro and in vivo evaluation of the radiosensitizing effect of a selective FGFR inhibitor (JNJ-42756493) for rectal cancer. | ||||||||||
| Author: | Verstraete, Maud|Debucquoy, Annelies|Gonnissen, Annelies|Dok, Ruveyda|Isebaert, Sofie|Devos, Ellen|McBride, William|Haustermans, Karin | ||||||||||
| PMID: | 26675289 | ||||||||||
| 32. | |||||||||||
| Journal: | Med Oncol. 2016 Oct;33(10):106. | ||||||||||
| Title: | Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing. | ||||||||||
| Author: | Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam | ||||||||||
| PMID: | 27568332 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Cancer. 2016 Oct 18;15(1):63. | ||||||||||
| Title: | Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing. | ||||||||||
| Author: | Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke | ||||||||||
| PMID: | 27756406 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 8;7(45):72908-72922. | ||||||||||
| Title: | Genomic characterization of liver metastases from colorectal cancer patients. | ||||||||||
| Author: | Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant | ||||||||||
| PMID: | 27662660 | ||||||||||
| 35. | |||||||||||
| Journal: | Gastroenterology. 2016 Aug;151(2):278-287.e6. | ||||||||||
| Title: | Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. | ||||||||||
| Author: | Yaeger, Rona|Shah, Manish A|Miller, Vincent A|Kelsen, Judith R|Wang, Kai|Heins, Zachary J|Ross, Jeffrey S|He, Yuting|Sanford, Eric|Yantiss, Rhonda K|Balasubramanian, Sohail|Stephens, Philip J|Schultz, Nikolaus|Oren, Moshe|Tang, Laura|Kelsen, David | ||||||||||
| PMID: | 27063727 | ||||||||||
| 36. | |||||||||||
| Journal: | Tumour Biol. 2016 Aug;37(8):10209-18. | ||||||||||
| Title: | Clinical significance of fibroblast growth factor receptor 2 expression in patients with residual rectal cancer after preoperative chemoradiotherapy: relationship with KRAS or BRAF mutations and MSI status. | ||||||||||
| Author: | Yoon, Ghilsuk|Lee, Hwayoung|Kim, Jae-Hoon|Hur, Keun|Seo, An Na | ||||||||||
| PMID: | 26831663 | ||||||||||
| 37. | |||||||||||
| Journal: | Br J Cancer. 2017 Jun 27;117(1):136-143. | ||||||||||
| Title: | Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. | ||||||||||
| Author: | Chakrabarty, Sanjiban|Varghese, Vinay Koshy|Sahu, Pranoy|Jayaram, Pradyumna|Shivakumar, Bhadravathi M|Pai, Cannanore Ganesh|Satyamoorthy, Kapaettu | ||||||||||
| PMID: | 28524162 | ||||||||||
| 38. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. | ||||||||||
| Title: | The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K | ||||||||||
| PMID: | 28675510 | ||||||||||
| 39. | |||||||||||
| Journal: | Cold Spring Harb Mol Case Stud. 2017 Nov 21;3(6). pii: mcs.a001495. | ||||||||||
| Title: | FGFR2 amplification in colorectal adenocarcinoma. | ||||||||||
| Author: | Carter, Jamal H|Cottrell, Catherine E|McNulty, Samantha N|Vigh-Conrad, Katinka A|Lamp, Stephen|Heusel, Jonathan W|Duncavage, Eric J | ||||||||||
| PMID: | 28835367 | ||||||||||
| 40. | |||||||||||
| Journal: | Cancer Genomics Proteomics. 2017 Sep-Oct;14(5):341-348. | ||||||||||
| Title: | Colitic Cancer Develops Through Mutational Alteration Distinct from that in Sporadic Colorectal Cancer: A Comparative Analysis of Mutational Rates at Each Step. | ||||||||||
| Author: | Tanaka, Toshiaki|Kobunai, Takashi|Yamamoto, Yoko|Emoto, Shigenobu|Murono, Koji|Kaneko, Manabu|Sasaki, Kazuhito|Otani, Kensuke|Nishikawa, Takeshi|Kawai, Kazushige|Hata, Keisuke|Nozawa, Hiroaki|Watanabe, Toshiaki | ||||||||||
| PMID: | 28871001 | ||||||||||
| 41. | |||||||||||
| Journal: | Mol Oncol. 2018 Jun;12(7):993-1003. | ||||||||||
| Title: | FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers in vitro. | ||||||||||
| Author: | Cha, Yongjun|Kim, Hwang-Phill|Lim, Yoojoo|Han, Sae-Won|Song, Sang-Hyun|Kim, Tae-You | ||||||||||
| PMID: | 29573334 | ||||||||||
| 42. | |||||||||||
| Journal: | EBioMedicine. 2018 Jul;33:68-81. | ||||||||||
| Title: | A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer. | ||||||||||
| Author: | El-Athman, Rukeia|Fuhr, Luise|Relogio, Angela | ||||||||||
| PMID: | 29936137 | ||||||||||
| 43. | |||||||||||
| Journal: | Oncotarget. 2018 Aug 14;9(63):32204-32218. | ||||||||||
| Title: | FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis. | ||||||||||
| Author: | Fromme, Julia Elisabeth|Schmitz, Katja|Wachter, Astrid|Grzelinski, Marius|Zielinski, Dirk|Koppel, Christina|Conradi, Lena-Christin|Homayounfar, Kia|Hugo, Tabea|Hugo, Sara|Lukat, Laura|Ruschoff, Josef|Strobel, Philipp|Ghadimi, Michael|Beissbarth, Tim|Reute | ||||||||||
| PMID: | 30181810 | ||||||||||