Primary Site >> Stomach Cancer

Gene >> FGFR1

Journal: Cancer. 1993 Sep 1;72(5):1522-7.
Title: CDw75 antigen expression in human gastric carcinoma and adjacent mucosa.
Author: David, L|Nesland, J M|Funderud, S|Sobrinho-Simoes, M
PMID: 8348485
Journal: Biochem Biophys Res Commun. 1994 Mar 30;199(3):1113-9.
Title: Expression of fibroblast growth factor gene family and its receptor gene family in the human upper gastrointestinal tract.
Author: Iida, S|Katoh, O|Tokunaga, A|Terada, M
PMID: 7511892
Journal: Int J Mol Med. 2003 May;11(5):579-83.
Title: Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 12684693
Journal: World J Gastroenterol. 2008 Oct 7;14(37):5650-6.
Title: Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers.
Author: Oki, Mariko|Yamamoto, Hiroyuki|Taniguchi, Hiroaki|Adachi, Yasushi|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 18837080
Journal: Int J Oncol. 2010 Jan;36(1):101-6.
Title: Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer.
Author: Gong, Jian|Morishita, Asahiro|Kurokohchi, Kazutaka|Tani, Joji|Kato, Kiyohito|Miyoshi, Hisaaki|Inoue, Hideyuki|Kobayashi, Mitsuyoshi|Liu, Shi|Murota, Masayuki|Muramatsu, Akemi|Izuishi, Kunihiko|Suzuki, Yasuyuki|Yoshida, Hirohito|Uchida, Naohito|Deguchi, Ka
PMID: 19956838
Journal: Expert Rev Anticancer Ther. 2010 Sep;10(9):1375-9.
Title: Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics.
Author: Katoh, Masaru
PMID: 20836672
Journal: Br J Cancer. 2012 Feb 14;106(4):727-32.
Title: FGFR2 gene amplification and clinicopathological features in gastric cancer.
Author: Matsumoto, K|Arao, T|Hamaguchi, T|Shimada, Y|Kato, K|Oda, I|Taniguchi, H|Koizumi, F|Yanagihara, K|Sasaki, H|Nishio, K|Yamada, Y
PMID: 22240789
Journal: World J Gastroenterol. 2012 Apr 14;18(14):1602-9.
Title: Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-kappaB/bFGF signaling.
Author: Guo, Jun-Li|Zheng, Shao-Jiang|Li, Yue-Nan|Jie, Wei|Hao, Xin-Bao|Li, Tian-Fa|Xia, Li-Ping|Mei, Wen-Li|Huang, Feng-Ying|Kong, Yue-Qiong|He, Qi-Yi|Yang, Kun|Tan, Guang-Hong|Dai, Hao-Fu
PMID: 22529688
Journal: Cancer Res. 2012 Sep 1;72(17):4383-93.
Title: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Author: Dulak, Austin M|Schumacher, Steven E|van Lieshout, Jasper|Imamura, Yu|Fox, Cameron|Shim, Byoungyong|Ramos, Alex H|Saksena, Gordon|Baca, Sylvan C|Baselga, Jose|Tabernero, Josep|Barretina, Jordi|Enzinger, Peter C|Corso, Giovanni|Roviello, Franco|Lin, Lin|Ba
PMID: 22751462
Journal: Tumour Biol. 2013 Apr;34(2):793-803.
Title: miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer.
Author: Wen, Dacheng|Li, Songhe|Ji, Fujian|Cao, Hong|Jiang, Weidong|Zhu, Jiaming|Fang, Xuedong
PMID: 23296701
Journal: Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Title: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Author: Burbridge, Mike F|Bossard, Celine J|Saunier, Carine|Fejes, Imre|Bruno, Alain|Leonce, Stephane|Ferry, Gilles|Da Violante, Georges|Bouzom, Francois|Cattan, Valerie|Jacquet-Bescond, Anne|Comoglio, Paolo M|Lockhart, Brian P|Boutin, Jean A|Cordi, Alex|Ortuno,
PMID: 23804704
Journal: Acta Pharm Hung. 2013;83(2):47-56.
Title: [Developing FGFR inhibitors as potential anti-cancer agents].
Author: Zsakai, Lilian|Nemeth, Gabor|Szantai-Kis, Csaba|Greff, Zoltan|Horvath, Zoltan|Szokol, Balint|Baska, Ferenc|Boon, Tin Chuad|Orfi, Laszlo|Keri, Gyorgya
PMID: 23926649
Journal: Mol Clin Oncol. 2014 Jul;2(4):509-517.
Title: Prognostic significance of the co-overexpression of fibroblast growth factor receptors 1, 2 and 4 in gastric cancer.
Author: Murase, Hideaki|Inokuchi, Mikito|Takagi, Yoko|Kato, Keiji|Kojima, Kazuyuki|Sugihara, Kenichi
PMID: 24940486
Journal: Med Res Rev. 2014 Mar;34(2):280-300.
Title: FGF receptors: cancer biology and therapeutics.
Author: Katoh, Masaru|Nakagama, Hitoshi
PMID: 23696246
Journal: Anticancer Drugs. 2015 Apr;26(4):379-87.
Title: The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer.
Author: Xu, Chaochao|Li, Wulan|Qiu, Peihong|Xia, Yiqun|Du, Xiaojing|Wang, Fen|Shen, Lailai|Chen, Qiuxiang|Zhao, Yunjie|Jin, Rong|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 25521558
Journal: Hum Pathol. 2015 Oct;46(10):1488-95.
Title: Fibroblast growth factor receptor 1 gene amplification in gastric adenocarcinoma.
Author: Schafer, Manuel H|Lingohr, Philipp|Strasser, Anke|Lehnen, Nils C|Braun, Martin|Perner, Sven|Holler, Tobias|Kristiansen, Glen|Kalff, Jorg C|Gutgemann, Ines
PMID: 26239623
Journal: Anticancer Res. 2015 Dec;35(12):6655-65.
Title: Targeting Fibroblast Growth Factor Receptor (FGFR) with BGJ398 in a Gastric Cancer Model.
Author: Schmidt, Katharina|Moser, Christian|Hellerbrand, Claus|Zieker, Derek|Wagner, Christine|Redekopf, Julia|Schlitt, Hans J|Geissler, Edward K|Lang, Sven A
PMID: 26637881
Journal: Cancer Discov. 2016 Aug;6(8):838-851.
Title: High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.
Author: Pearson, Alex|Smyth, Elizabeth|Babina, Irina S|Herrera-Abreu, Maria Teresa|Tarazona, Noelia|Peckitt, Clare|Kilgour, Elaine|Smith, Neil R|Geh, Catherine|Rooney, Claire|Cutts, Ros|Campbell, James|Ning, Jian|Fenwick, Kerry|Swain, Amanda|Brown, Gina|Chua, Sue
PMID: 27179038
Journal: Int J Mol Med. 2016 Jul;38(1):3-15.
Title: FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).
Author: Katoh, Masaru
PMID: 27245147
Journal: Oncotarget. 2016 Aug 23;7(34):54445-54462.
Title: Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation.
Author: Saisana, Marina|Griffin, S Michael|May, Felicity E B
PMID: 27437872
Journal: Eur J Med Chem. 2017 Feb 15;127:885-899.
Title: Synthesis, biological evaluation, QSAR and molecular dynamics simulation studies of potential fibroblast growth factor receptor 1 inhibitors for the treatment of gastric cancer.
Author: Ying, Shilong|Du, Xiaojing|Fu, Weitao|Yun, Di|Chen, Liping|Cai, Yuepiao|Xu, Qing|Wu, Jianzhang|Li, Wulan|Liang, Guang
PMID: 27829519
Journal: World J Surg Oncol. 2017 Jan 5;15(1):2.
Title: Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.
Author: Inokuchi, Mikito|Murase, Hideaki|Otsuki, Sho|Kawano, Tatsuyuki|Kojima, Kazuyuki
PMID: 28056982
Journal: Apoptosis. 2017 Jun;22(6):852-864.
Title: A novel non-ATP competitive FGFR1 inhibitor with therapeutic potential on gastric cancer through inhibition of cell proliferation, survival and migration.
Author: Wu, Jianzhang|Du, Xiaojing|Li, Wulan|Zhou, Yangyang|Bai, Encheng|Kang, Yanting|Chen, Qiuxiang|Fu, Weitao|Yun, Di|Xu, Qing|Qiu, Peihong|Jin, Rong|Cai, Yuepiao|Liang, Guang
PMID: 28315172
Journal: J Exp Clin Cancer Res. 2017 Nov 13;36(1):158.
Title: MiR-361-5p inhibits glycolytic metabolism, proliferation and invasion of breast cancer by targeting FGFR1 and MMP-1.
Author: Ma, Fei|Zhang, Lei|Ma, Li|Zhang, Yiyun|Zhang, Jianguo|Guo, Baoliang
PMID: 29132384
Journal: NPJ Precis Oncol. 2017 May 1;1(1):9.
Title: Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival.
Author: Leong, Siew Hong|Lwin, Kyaw Myo|Lee, Sze Sing|Ng, Wai Har|Ng, Kia Min|Tan, Soo Yong|Ng, Bee Ling|Carter, Nigel P|Tang, Carol|Lian Kon, Oi
PMID: 29872697
Journal: Acta Pharmacol Sin. 2018 Feb;39(2):243-250.
Title: SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models.
Author: Jiang, Xi-Fei|Dai, Yang|Peng, Xia|Shen, Yan-Yan|Su, Yi|Wei, Man-Man|Liu, Wei-Ren|Ding, Zhen-Bin|Zhang, Ao|Shi, Ying-Hong|Ai, Jing
PMID: 28905937
Journal: Cancer Genomics Proteomics. 2018 Jul-Aug;15(4):313-320.
Title: Overexpression of FGFR1 Promotes Peritoneal Dissemination Via Epithelial-to-Mesenchymal Transition in Gastric Cancer.
Author: Shimizu, Dai|Saito, Tomoko|Ito, Shuhei|Masuda, Takaaki|Kurashige, Junji|Kuroda, Yosuke|Eguchi, Hidetoshi|Kodera, Yasuhiro|Mimori, Koshi
PMID: 29976636