Primary Site >> Stomach Cancer
Gene >> FGFR1
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Ref: CDw75 antigen expression in human gastric carcinoma and adjacent mucosa. PMID: 8348485 |
Ref: Expression of fibroblast growth factor gene family and its receptor gene family in the human upper gastrointestinal tract. PMID: 7511892 |
Ref: Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26. PMID: 12684693 |
Ref: Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers. PMID: 18837080 |
Ref: Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer. PMID: 19956838 Ref: Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics. PMID: 20836672 |
Ref: FGFR2 gene amplification and clinicopathological features in gastric cancer. PMID: 22240789 Ref: Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-kappaB/bFGF signaling. PMID: 22529688 Ref: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. PMID: 22751462 |
Ref: miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer. PMID: 23296701 Ref: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. PMID: 23804704 Ref: [Developing FGFR inhibitors as potential anti-cancer agents]. PMID: 23926649 |
Ref: FGF receptors: cancer biology and therapeutics. PMID: 23696246 Ref: Prognostic significance of the co-overexpression of fibroblast growth factor receptors 1, 2 and 4 in gastric cancer. PMID: 24940486 |
Ref: The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. PMID: 25521558 Ref: Fibroblast growth factor receptor 1 gene amplification in gastric adenocarcinoma. PMID: 26239623 Ref: Targeting Fibroblast Growth Factor Receptor (FGFR) with BGJ398 in a Gastric Cancer Model. PMID: 26637881 |
Ref: High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial. PMID: 27179038 Ref: FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review). PMID: 27245147 Ref: Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. PMID: 27437872 |
Ref: Synthesis, biological evaluation, QSAR and molecular dynamics simulation studies of potential fibroblast growth factor receptor 1 inhibitors for the treatment of gastric cancer. PMID: 27829519 Ref: Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer. PMID: 28056982 Ref: A novel non-ATP competitive FGFR1 inhibitor with therapeutic potential on gastric cancer through inhibition of cell proliferation, survival and migration. PMID: 28315172 Ref: MiR-361-5p inhibits glycolytic metabolism, proliferation and invasion of breast cancer by targeting FGFR1 and MMP-1. PMID: 29132384 Ref: Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival. PMID: 29872697 |
Ref: SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models. PMID: 28905937 Ref: Overexpression of FGFR1 Promotes Peritoneal Dissemination Via Epithelial-to-Mesenchymal Transition in Gastric Cancer. PMID: 29976636 |