Primary Site >> Colorectal Cancer

Gene >> FGFR1

Journal: Cancer Res. 1994 Oct 1;54(19):5206-11.
Title: Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium.
Author: Murgue, B|Tsunekawa, S|Rosenberg, I|deBeaumont, M|Podolsky, D K
PMID: 7923141
Journal: Biochem Pharmacol. 2000 Oct 1;60(7):885-98.
Title: Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.
Author: Kraker, A J|Hartl, B G|Amar, A M|Barvian, M R|Showalter, H D|Moore, C W
PMID: 10974196
Journal: Curr Med Chem. 2001 Oct;8(12):1487-503.
Title: Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.
Author: Owa, T|Yoshino, H|Yoshimatsu, K|Nagasu, T
PMID: 11562278
Journal: Oncogene. 2005 Jan 27;24(5):945-8.
Title: Reciprocal relationship in gene expression between FGFR1 and FGFR3: implication for tumorigenesis.
Author: Jang, Jun-Hyeog
PMID: 15558020
Journal: Oncogene. 2006 Sep 14;25(41):5693-706. Epub 2006 Apr 24.
Title: High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation.
Author: Pole, J C M|Courtay-Cahen, C|Garcia, M J|Blood, K A|Cooke, S L|Alsop, A E|Tse, D M L|Caldas, C|Edwards, P A W
PMID: 16636668
Journal: Oncogene. 2007 Mar 29;26(14):2133-5. Epub 2006 Oct 2.
Title: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.
Author: Shao, R-X|Kato, N|Lin, L-J|Muroyama, R|Moriyama, M|Ikenoue, T|Watabe, H|Otsuka, M|Guleng, B|Ohta, M|Tanaka, Y|Kondo, S|Dharel, N|Chang, J-H|Yoshida, H|Kawabe, T|Omata, M
PMID: 17016444
Journal: Cancer Res. 2008 Dec 1;68(23):9754-62.
Title: TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche.
Author: Yamamoto, Masayoshi|Kikuchi, Hirotoshi|Ohta, Manabu|Kawabata, Toshiki|Hiramatsu, Yoshihiro|Kondo, Kenji|Baba, Megumi|Kamiya, Kinji|Tanaka, Tatsuo|Kitagawa, Masatoshi|Konno, Hiroyuki
PMID: 19047154
Journal: Arch Oral Biol. 2009 Jan;54(1):45-9.
Title: Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis.
Author: Callahan, N|Modesto, A|Meira, R|Seymen, F|Patir, A|Vieira, A R
PMID: 18790474
Journal: Int J Oncol. 2010 Oct;37(4):829-35.
Title: The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer.
Author: Morishita, Asahiro|Gong, Jian|Nomura, Takako|Yoshida, Hirohito|Izuishi, Kunihiko|Suzuki, Yasuyuki|Kushida, Yoshio|Haba, Reiji|D'Armiento, Jeanine|Masaki, Tsutomu
PMID: 20811704
Journal: Cancer Res. 2012 Sep 1;72(17):4383-93. Epub 2012 Jul 2.
Title: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Author: Dulak, Austin M|Schumacher, Steven E|van Lieshout, Jasper|Imamura, Yu|Fox, Cameron|Shim, Byoungyong|Ramos, Alex H|Saksena, Gordon|Baca, Sylvan C|Baselga, Jose|Tabernero, Josep|Barretina, Jordi|Enzinger, Peter C|Corso, Giovanni|Roviello, Franco|Lin, Lin|Ba
PMID: 22751462
Journal: Patholog Res Int. 2012;2012:574768.
Title: Fibroblast growth factor receptor 2: expression, roles, and potential as a novel molecular target for colorectal cancer.
Author: Matsuda, Yoko|Ueda, Junji|Ishiwata, Toshiyuki
PMID: 22701813
Journal: Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Title: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Author: Burbridge, Mike F|Bossard, Celine J|Saunier, Carine|Fejes, Imre|Bruno, Alain|Leonce, Stephane|Ferry, Gilles|Da Violante, Georges|Bouzom, Francois|Cattan, Valerie|Jacquet-Bescond, Anne|Comoglio, Paolo M|Lockhart, Brian P|Boutin, Jean A|Cordi, Alex|Ortuno,
PMID: 23804704
Journal: Eur J Cancer. 2013 Oct;49(15):3076-82.
Title: Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.
Author: Wiesweg, Marcel|Ting, Saskia|Reis, Henning|Worm, Karl|Kasper, Stefan|Tewes, Mitra|Welt, Anja|Richly, Heike|Meiler, Johannes|Bauer, Sebastian|Hense, Jorg|Gauler, Thomas C|Kohler, Jens|Eberhardt, Wilfried E|Darwiche, Kaid|Freitag, Lutz|Stamatis, Georgios|Br
PMID: 23876834
Journal: Digestion. 2013;88(3):172-81.
Title: Fibroblast growth factor receptor 1 as a putative therapy target in colorectal cancer.
Author: Goke, Friederike|Goke, Antonia|von Massenhausen, Anne|Franzen, Alina|Sharma, Rakesh|Kirsten, Robert|Bohm, Diana|Kristiansen, Glen|Stenzinger, Albrecht|Wynes, Murry|Hirsch, Fred R|Weichert, Wilko|Heasley, Lynn|Buettner, Reinhard|Perner, Sven
PMID: 24135816
Journal: Hepatology. 2014 Aug;60(2):598-609.
Title: Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression.
Author: Chen, Dong-Liang|Wang, Zhi-Qiang|Zeng, Zhao-Lei|Wu, Wen-Jing|Zhang, Dong-Sheng|Luo, Hui-Yan|Wang, Feng|Qiu, Miao-Zhen|Wang, De-Shen|Ren, Chao|Wang, Feng-Hua|Chiao, Lucia J|Pelicano, Helene|Huang, Peng|Li, Yu-Hong|Xu, Rui-Hua
PMID: 24616020
Journal: PLoS One. 2014 Jul 10;9(7):e101957.
Title: SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer.
Author: Lundberg, Ida V|Lofgren Burstrom, Anna|Edin, Sofia|Eklof, Vincy|Oberg, Ake|Stenling, Roger|Palmqvist, Richard|Wikberg, Maria L
PMID: 25010701
Journal: Acta Neuropathol. 2014 Dec;128(6):879-91.
Title: Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.
Author: Berghoff, Anna Sophie|Bartsch, Rupert|Wohrer, Adelheid|Streubel, Berthold|Birner, Peter|Kros, Johan M|Brastianos, Priscilla K|von Deimling, Andreas|Preusser, Matthias
PMID: 25287912
Journal: Am J Cancer Res. 2014 Dec 15;5(1):72-86. eCollection 2015.
Title: Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer.
Author: Lee, Choong-Kun|Lee, Myung Eun|Lee, Won Suk|Kim, Jeong Min|Park, Kyu Hyun|Kim, Tae Soo|Lee, Kang Young|Ahn, Joong Bae|Chung, Hyun Cheol|Rha, Sun Young
PMID: 25628921
Journal: J Hematol Oncol. 2015 Oct 24;8:119.
Title: Complexity of FGFR signalling in metastatic urothelial cancer.
Author: Rodriguez-Vida, Alejo|Saggese, Matilde|Hughes, Simon|Rudman, Sarah|Chowdhury, Simon|Smith, Neil R|Lawrence, Peter|Rooney, Claire|Dougherty, Brian|Landers, Donal|Kilgour, Elaine|Arkenau, Hendrik-Tobias
PMID: 26497743
Journal: Nature. 2015 Oct 8;526(7572):263-7.
Title: The genomic landscape of response to EGFR blockade in colorectal cancer.
Author: Bertotti, Andrea|Papp, Eniko|Jones, Sian|Adleff, Vilmos|Anagnostou, Valsamo|Lupo, Barbara|Sausen, Mark|Phallen, Jillian|Hruban, Carolyn A|Tokheim, Collin|Niknafs, Noushin|Nesselbush, Monica|Lytle, Karli|Sassi, Francesco|Cottino, Francesca|Migliardi, Giorg
PMID: 26416732
Journal: Pathobiology. 2015;82(2):76-83.
Title: Fibroblast Growth Factor Receptor 1 Gene Copy Number and mRNA Expression in Primary Colorectal Cancer and Its Clinicopathologic Correlation.
Author: Kwak, Yoonjin|Nam, Soo Kyung|Seo, An Na|Kim, Duck-Woo|Kang, Sung-Bum|Kim, Woo Ho|Lee, Hye Seung
PMID: 26088290
Journal: Comp Biochem Physiol B Biochem Mol Biol. 2015 Aug;186:43-50.
Title: Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents.
Author: Zhuang, Lei|Bluteau, Gilles|Trueb, Beat
PMID: 25934085
Journal: Tumour Biol. 2015 Jul;36(7):5641-8.
Title: AZD-4547 exerts potent cytostatic and cytotoxic activities against fibroblast growth factor receptor (FGFR)-expressing colorectal cancer cells.
Author: Yao, Ting-Jing|Zhu, Jin-Hai|Peng, De-Feng|Cui, Zhen|Zhang, Chao|Lu, Pei-hua
PMID: 25691251
Journal: Cancer Biol Ther. 2016;17(2):199-207.
Title: EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.
Author: Zhang, Jiayin|Lu, Biao|Liu, Dong|Shen, Ru|Yan, Yinfa|Yang, Liuqing|Zhang, Minsheng|Zhang, Lei|Cao, Guoqing|Cao, Hu|Fu, Beibei|Gong, Aishen|Sun, Qiming|Wan, Hong|Zhang, Lianshan|Tao, Weikang|Cao, Jingsong
PMID: 26810733
Journal: Gastroenterology. 2016 Aug;151(2):278-287.e6.
Title: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease.
Author: Yaeger, Rona|Shah, Manish A|Miller, Vincent A|Kelsen, Judith R|Wang, Kai|Heins, Zachary J|Ross, Jeffrey S|He, Yuting|Sanford, Eric|Yantiss, Rhonda K|Balasubramanian, Sohail|Stephens, Philip J|Schultz, Nikolaus|Oren, Moshe|Tang, Laura|Kelsen, David
PMID: 27063727
Journal: Nature. 2016 Jun 30;534(7609):647-51.
Title: A combinatorial strategy for treating KRAS-mutant lung cancer.
Author: Manchado, Eusebio|Weissmueller, Susann|Morris, John P 4th|Chen, Chi-Chao|Wullenkord, Ramona|Lujambio, Amaia|de Stanchina, Elisa|Poirier, John T|Gainor, Justin F|Corcoran, Ryan B|Engelman, Jeffrey A|Rudin, Charles M|Rosen, Neal|Lowe, Scott W
PMID: 27338794
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title: [A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author: Yagi, Ryoma|Shimada, Yoshifumi|Miura, Kohei|Tajima, Yosuke|Okamura, Takuma|Nakano, Masato|Ichikawa, Hiroshi|Nagahashi, Masayuki|Sakata, Jun|Kobayashi, Takashi|Kameyama, Hitoshi|Wakai, Toshifumi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa
PMID: 28133136
Journal: Oncotarget. 2017 Feb 7;8(6):10007-10024.
Title: The RNA-binding protein ESRP1 promotes human colorectal cancer progression.
Author: Fagoonee, Sharmila|Picco, Gabriele|Orso, Francesca|Arrigoni, Arrigo|Longo, Dario L|Forni, Marco|Scarfo, Irene|Cassenti, Adele|Piva, Roberto|Cassoni, Paola|Silengo, Lorenzo|Tolosano, Emanuela|Aime, Silvio|Taverna, Daniela|Pandolfi, Pier Paolo|Brancaccio, M
PMID: 28052020
Journal: Cancer Res. 2017 May 15;77(10):2746-2758.
Title: miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis.
Author: Jiang, Longchang|Hermeking, Heiko
PMID: 28363996
Journal: Oncotarget. 2017 Dec 15;9(3):3394-3405.
Title: Copy number profiles of paired primary and metastatic colorectal cancers.
Author: Kawamata, Futoshi|Patch, Ann-Marie|Nones, Katia|Bond, Catherine|McKeone, Diane|Pearson, Sally-Ann|Homma, Shigenori|Liu, Cheng|Fennell, Lochlan|Dumenil, Troy|Hartel, Gunter|Kobayasi, Nozomi|Yokoo, Hideki|Fukai, Moto|Nishihara, Hiroshi|Kamiyama, Toshiya|Bur
PMID: 29423054
Journal: J Cancer Res Ther. 2018 Apr-Jun;14(3):527-531.
Title: Tooth agenesis: A susceptible indicator for colorectal cancer?
Author: Paranjyothi, M V|Kumaraswamy, K L|Begum, Lubna Firdose|Manjunath, K|Basheer, Shaini
PMID: 29893310
Journal: Cancer Control. 2018 Jan-Dec;25(1):1073274818789361.
Title: Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers.
Author: Suyama, Koichi|Iwase, Hirotaka
PMID: 30032643
Journal: Anticancer Drugs. 2018 Oct;29(9):827-838.
Title: Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.
Author: Capasso, Anna|Pitts, Todd M|Klauck, Peter J|Bagby, Stacey M|Westbrook, Lindsey|Kaplan, Jeffrey|Soleimani, Milad|Spreafico, Anna|Tentler, John J|Diamond, Jennifer R|Arcaroli, John J|Messersmith, Wells A|Eckhardt, Sue G|Leong, Stephen
PMID: 30048249
Journal: Oncotarget. 2018 Aug 14;9(63):32204-32218.
Title: FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis.
Author: Fromme, Julia Elisabeth|Schmitz, Katja|Wachter, Astrid|Grzelinski, Marius|Zielinski, Dirk|Koppel, Christina|Conradi, Lena-Christin|Homayounfar, Kia|Hugo, Tabea|Hugo, Sara|Lukat, Laura|Ruschoff, Josef|Strobel, Philipp|Ghadimi, Michael|Beissbarth, Tim|Reute
PMID: 30181810