Primary Site >> Colorectal Cancer
Gene >> FGFR1
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Ref: Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium. PMID: 7923141 |
Ref: Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors. PMID: 10974196 |
Ref: Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents. PMID: 11562278 |
Ref: Reciprocal relationship in gene expression between FGFR1 and FGFR3: implication for tumorigenesis. PMID: 15558020 |
Ref: High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. PMID: 16636668 |
Ref: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients. PMID: 17016444 |
Ref: TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche. PMID: 19047154 |
Ref: Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis. PMID: 18790474 |
Ref: The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer. PMID: 20811704 |
Ref: Fibroblast growth factor receptor 2: expression, roles, and potential as a novel molecular target for colorectal cancer. PMID: 22701813 Ref: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. PMID: 22751462 |
Ref: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. PMID: 23804704 Ref: Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center. PMID: 23876834 Ref: Fibroblast growth factor receptor 1 as a putative therapy target in colorectal cancer. PMID: 24135816 |
Ref: Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression. PMID: 24616020 Ref: SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer. PMID: 25010701 Ref: Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues. PMID: 25287912 |
Ref: Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer. PMID: 25628921 Ref: AZD-4547 exerts potent cytostatic and cytotoxic activities against fibroblast growth factor receptor (FGFR)-expressing colorectal cancer cells. PMID: 25691251 Ref: Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents. PMID: 25934085 Ref: Fibroblast Growth Factor Receptor 1 Gene Copy Number and mRNA Expression in Primary Colorectal Cancer and Its Clinicopathologic Correlation. PMID: 26088290 Ref: The genomic landscape of response to EGFR blockade in colorectal cancer. PMID: 26416732 Ref: Complexity of FGFR signalling in metastatic urothelial cancer. PMID: 26497743 |
Ref: EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile. PMID: 26810733 Ref: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. PMID: 27063727 Ref: A combinatorial strategy for treating KRAS-mutant lung cancer. PMID: 27338794 Ref: [A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy]. PMID: 28133136 |
Ref: The RNA-binding protein ESRP1 promotes human colorectal cancer progression. PMID: 28052020 Ref: miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis. PMID: 28363996 |
Ref: Copy number profiles of paired primary and metastatic colorectal cancers. PMID: 29423054 Ref: Tooth agenesis: A susceptible indicator for colorectal cancer? PMID: 29893310 Ref: Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers. PMID: 30032643 Ref: Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models. PMID: 30048249 Ref: FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis. PMID: 30181810 |