Primary Site >> Colorectal Cancer

Gene >> FGF19

Journal: Oncogene. 2008 Jan 3;27(1):85-97. Epub 2007 Jun 25.
Title: Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
Author: Desnoyers, L R|Pai, R|Ferrando, R E|Hotzel, K|Le, T|Ross, J|Carano, R|D'Souza, A|Qing, J|Mohtashemi, I|Ashkenazi, A|French, D M
PMID: 17599042
Journal: Cancer Res. 2008 Jul 1;68(13):5086-95.
Title: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
Author: Pai, Rama|Dunlap, Debra|Qing, Jing|Mohtashemi, Iman|Hotzel, Kathy|French, Dorothy M
PMID: 18593907
Journal: J Clin Invest. 2011 Aug;121(8):3220-32.
Title: Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice.
Author: Wang, Hongwei|Venkatesh, Madhukumar|Li, Hao|Goetz, Regina|Mukherjee, Subhajit|Biswas, Arunima|Zhu, Liang|Kaubisch, Andreas|Wang, Lei|Pullman, James|Whitney, Kathleen|Kuro-o, Makoto|Roig, Andres I|Shay, Jerry W|Mohammadi, Moosa|Mani, Sridhar
PMID: 21747170
Journal: Toxicol Sci. 2012 Apr;126(2):446-56.
Title: Antibody-mediated inhibition of fibroblast growth factor 19 results in increased bile acids synthesis and ileal malabsorption of bile acids in cynomolgus monkeys.
Author: Pai, Rama|French, Dorothy|Ma, Ning|Hotzel, Kathy|Plise, Emile|Salphati, Laurent|Setchell, Kenneth D R|Ware, Joseph|Lauriault, Veronique|Schutt, Leah|Hartley, Dylan|Dambach, Donna
PMID: 22268002
Journal: Adv Exp Med Biol. 2012;728:195-213.
Title: Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities.
Author: Wu, Xinle|Li, Yang
PMID: 22396171
Journal: J Steroid Biochem Mol Biol. 2012 Oct;132(1-2):41-7.
Title: Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19.
Author: Miyata, Masaaki|Hata, Tatsuya|Yamakawa, Hiroki|Kagawa, Tatehiro|Yoshinari, Kouichi|Yamazoe, Yasushi
PMID: 22561792
Journal: Mol Pharm. 2012 Sep 4;9(9):2565-76.
Title: Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.
Author: Herraez, Elisa|Gonzalez-Sanchez, Ester|Vaquero, Javier|Romero, Marta R|Serrano, Maria A|Marin, Jose J G|Briz, Oscar
PMID: 22800197
Journal: PLoS One. 2012;7(12):e52711.
Title: Regulation of amphiregulin gene expression by beta-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system.
Author: Latasa, Maria U|Salis, Fabiana|Urtasun, Raquel|Garcia-Irigoyen, Oihane|Elizalde, Maria|Uriarte, Iker|Santamaria, Monica|Feo, Francesco|Pascale, Rosa M|Prieto, Jesus|Berasain, Carmen|Avila, Matias A
PMID: 23285165
Journal: Asian Pac J Cancer Prev. 2013;14(5):3151-4.
Title: Lack of relationships between FGF19 staining pattern, lymph node metastasis and locally invasive characteristics of the tumor in colorectal cancers.
Author: Unal, Hakan Umit|Demiralay, Ebru|Tepeoglu, Merih|Fidan, Cihan|Kilickap, Saadettin
PMID: 23803094
Journal: Oncotarget. 2016 Mar 22;7(12):13575-86.
Title: FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3beta/beta- catenin signaling cascade via FGFR4 activation.
Author: Zhao, Huakan|Lv, Fenglin|Liang, Guizhao|Huang, Xiaobin|Wu, Gang|Zhang, Wenfa|Yu, Le|Shi, Lei|Teng, Yong
PMID: 26498355
Journal: J Vis Exp. 2016 Nov 27;(117).
Title: Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport.
Author: Felton, Jessica|Cheng, Kunrong|Said, Anan|Shang, Aaron C|Xu, Su|Vivian, Diana|Metry, Melissa|Polli, James E|Raufman, Jean-Pierre
PMID: 27929465
Journal: Postepy Hig Med Dosw (Online). 2017 Aug 24;71(1):737-746.
Title: The role of bile acids in the pathogenesis of bowel diseases.
Author: Panek-Jeziorna, Magdalena|Mulak, Agata
PMID: 28894048
Journal: Oncotarget. 2018 May 22;9(39):25572-25585.
Title: Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice.
Author: Cheng, Kunrong|Metry, Melissa|Felton, Jessica|Shang, Aaron C|Drachenberg, Cinthia B|Xu, Su|Zhan, Min|Schumacher, Justin|Guo, Grace L|Polli, James E|Raufman, Jean-Pierre
PMID: 29876009