Primary Site >> Colorectal Cancer

Gene >> FEN1

Journal: Int J Oncol. 2004 May;24(5):1279-88.
Title: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil.
Author: de Angelis, Paula M|Fjell, Bjorg|Kravik, Katherine L|Haug, Terje|Tunheim, Siv H|Reichelt, Wenche|Beigi, Marzieh|Clausen, Ole Petter|Galteland, Eivind|Stokke, Trond
PMID: 15067352
Journal: Carcinogenesis. 2005 Feb;26(2):411-6. Epub 2004 Nov 18.
Title: Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population.
Author: Yamamoto, Hiromasa|Hanafusa, Hiroko|Ouchida, Mamoru|Yano, Masaaki|Suzuki, Hiromitsu|Murakami, Masakazu|Aoe, Motoi|Shimizu, Nobuyoshi|Nakachi, Kei|Shimizu, Kenji
PMID: 15550454
Journal: Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3276-81.
Title: Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.
Author: McManus, Kirk J|Barrett, Irene J|Nouhi, Yasaman|Hieter, Philip
PMID: 19218431
Journal: Biochemistry. 2009 Oct 27;48(42):9952-8.
Title: Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development.
Author: Panda, Harekrushna|Jaiswal, Aruna S|Corsino, Patrick E|Armas, Melissa L|Law, Brian K|Narayan, Satya
PMID: 19769410
Journal: Mol Cancer Res. 2009 Dec;7(12):1973-83.
Title: A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.
Author: Jaiswal, Aruna S|Banerjee, Sanjeev|Panda, Harekrushna|Bulkin, Charles D|Izumi, Tadahide|Sarkar, Fazlul H|Ostrov, David A|Narayan, Satya
PMID: 19996303
Journal: Genet Test Mol Biomarkers. 2010 Oct;14(5):649-52.
Title: Impact of EXO1 polymorphism in susceptibility to colorectal cancer.
Author: Haghighi, Mahdi Montazer|Taleghani, Mohammad Yaghoob|Mohebbi, Seyed Reza|Vahedi, Mohsen|Fatemi, Seyed Reza|Zali, Narges|Shemirani, Atena Irani|Zali, Mohammad Reza
PMID: 20854105
Journal: PLoS One. 2011 Feb 2;6(2):e16691.
Title: DNA polymerase beta as a novel target for chemotherapeutic intervention of colorectal cancer.
Author: Jaiswal, Aruna S|Banerjee, Sanjeev|Aneja, Ritu|Sarkar, Fazlul H|Ostrov, David A|Narayan, Satya
PMID: 21311763
Journal: Carcinogenesis. 2012 Jan;33(1):119-23.
Title: Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer.
Author: Liu, Li|Zhou, Changchun|Zhou, Liqing|Peng, Li|Li, Dapeng|Zhang, Xiaojiao|Zhou, Mo|Kuang, Pengqun|Yuan, Qipeng|Song, Xianrang|Yang, Ming
PMID: 22072618
Journal: J Neurooncol. 2013 Jan;111(2):145-51.
Title: Functional FEN1 genetic variants and haplotypes are associated with glioma risk.
Author: Chen, Yi-Dong|Zhang, Xiaojiao|Qiu, Xiao-Guang|Li, Jinpeng|Yuan, Qipeng|Jiang, Tao|Yang, Ming
PMID: 23184144
Journal: World J Gastroenterol. 2013 Nov 14;19(42):7374-88.
Title: 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
Author: Das, Dipon|Preet, Ranjan|Mohapatra, Purusottam|Satapathy, Shakti Ranjan|Kundu, Chanakya Nath
PMID: 24259968
Journal: Nat Genet. 2014 Jun;46(6):533-42.
Title: Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Author: Zhang, Ben|Jia, Wei-Hua|Matsuda, Koichi|Kweon, Sun-Seog|Matsuo, Keitaro|Xiang, Yong-Bing|Shin, Aesun|Jee, Sun Ha|Kim, Dong-Hyun|Cai, Qiuyin|Long, Jirong|Shi, Jiajun|Wen, Wanqing|Yang, Gong|Zhang, Yanfeng|Li, Chun|Li, Bingshan|Guo, Yan|Ren, Zefang|Ji, Bu-T
PMID: 24836286
Journal: DNA Repair (Amst). 2014 Dec;24:15-25.
Title: 5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway.
Author: Das, Dipon|Preet, Ranjan|Mohapatra, Purusottam|Satapathy, Shakti Ranjan|Siddharth, Sumit|Tamir, Tigist|Jain, Vaibhav|Bharatam, Prasad V|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 25460919
Journal: PLoS One. 2015 May 1;10(5):e0123808.
Title: NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase beta and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
Author: Jaiswal, Aruna S|Panda, Harekrushna|Law, Brian K|Sharma, Jay|Jani, Jitesh|Hromas, Robert|Narayan, Satya
PMID: 25933036
Journal: Cancer Genomics Proteomics. 2016 Jan-Feb;13(1):69-74.
Title: The Association of Flap Endonuclease 1 Genotypes with the Risk of Childhood Leukemia.
Author: Pei, Jen-Sheng|Chang, Wen-Shin|Hsu, Pei-Chen|Tsai, Chia-Wen|Hsu, Chin-Mu|Ji, Hong-Xue|Hsiao, Chieh-Lun|Hsu, Yuan-Nian|Bau, Da-Tian
PMID: 26708601
Journal: DNA Repair (Amst). 2016 May;41:54-62.
Title: Interaction between APC and Fen1 during breast carcinogenesis.
Author: Narayan, Satya|Jaiswal, Aruna S|Law, Brian K|Kamal, Mohammad A|Sharma, Arun K|Hromas, Robert A
PMID: 27088617
Journal: G3 (Bethesda). 2017 May 5;7(5):1463-1473.
Title: Schizosaccharomyces pombe MutSalpha and MutLalpha Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats.
Author: Villahermosa, Desiree|Christensen, Olaf|Knapp, Karen|Fleck, Oliver
PMID: 28341698
Journal: Mol Biosyst. 2017 Jul 25;13(8):1630-1639.
Title: Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.
Author: Deshmukh, Amit Laxmikant|Chandra, Sharat|Singh, Deependra Kumar|Siddiqi, Mohammad Imran|Banerjee, Dibyendu
PMID: 28685785
Journal: Cancer Genomics Proteomics. 2017 Nov-Dec;14(6):455-460.
Title: The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis.
Author: Chou, An-Kuo|Shen, Ming-Yi|Chen, Fang-Yu|Hsiao, Chieh-Lun|Shih, Liang-Chun|Chang, Wen-Shin|Tsai, Chia-Wen|Ying, Tsung-Ho|Wu, Ming-Hsien|Huang, Chung-Yu|Bau, DA-Tian
PMID: 29109095
Journal: Pathol Res Pract. 2018 Jan;214(1):64-71.
Title: Prognostic impact of changes in base excision repair machinery in sporadic colorectal cancer.
Author: Azambuja, Daniel B|Leguisamo, Natalia M|Gloria, Helena C|Kalil, Antonio Nocchi|Rhoden, Ernani|Saffi, Jenifer
PMID: 29254784
Journal: Cancer Sci. 2018 Aug;109(8):2458-2468.
Title: HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells.
Author: Sakuma, Keiichiro|Sasaki, Eiichi|Kimura, Kenya|Komori, Koji|Shimizu, Yasuhiro|Yatabe, Yasushi|Aoki, Masahiro
PMID: 29869816
Journal: Aging (Albany NY). 2018 Aug 22;10(8):2062-2078.
Title: LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer.
Author: Ma, Siping|Yang, Dongxiang|Liu, Yanlong|Wang, Yongpeng|Lin, Tao|Li, Yanxi|Yang, Shihua|Zhang, Wanchuan|Zhang, Rui
PMID: 30144787