Primary Site >> Colorectal Cancer
Gene >> FEN1
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Ref: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil. PMID: 15067352 |
Ref: Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population. PMID: 15550454 |
Ref: Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing. PMID: 19218431 Ref: Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development. PMID: 19769410 Ref: A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells. PMID: 19996303 |
Ref: Impact of EXO1 polymorphism in susceptibility to colorectal cancer. PMID: 20854105 |
Ref: DNA polymerase beta as a novel target for chemotherapeutic intervention of colorectal cancer. PMID: 21311763 |
Ref: Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer. PMID: 22072618 |
Ref: Functional FEN1 genetic variants and haplotypes are associated with glioma risk. PMID: 23184144 Ref: 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells. PMID: 24259968 |
Ref: Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. PMID: 24836286 Ref: 5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway. PMID: 25460919 |
Ref: NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase beta and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells. PMID: 25933036 |
Ref: The Association of Flap Endonuclease 1 Genotypes with the Risk of Childhood Leukemia. PMID: 26708601 Ref: Interaction between APC and Fen1 during breast carcinogenesis. PMID: 27088617 |
Ref: Schizosaccharomyces pombe MutSalpha and MutLalpha Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats. PMID: 28341698 Ref: Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening. PMID: 28685785 Ref: The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis. PMID: 29109095 |
Ref: Prognostic impact of changes in base excision repair machinery in sporadic colorectal cancer. PMID: 29254784 Ref: HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells. PMID: 29869816 Ref: LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer. PMID: 30144787 |