Primary Site >> Pancreatic Cancer
Gene >> FBXW7
| 1. | |||||||||||
| Journal: | Am J Pathol. 2003 Oct;163(4):1255-60. | ||||||||||
| Title: | BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets. | ||||||||||
| Author: | Calhoun, Eric S|Jones, Jessa B|Ashfaq, Raheela|Adsay, Volkan|Baker, Suzanne J|Valentine, Virginia|Hempen, Paula M|Hilgers, Werner|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E | ||||||||||
| PMID: | 14507635 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2007 Apr 15;67(8):3545-50. | ||||||||||
| Title: | Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma. | ||||||||||
| Author: | Balakrishnan, Asha|Bleeker, Fonnet E|Lamba, Simona|Rodolfo, Monica|Daniotti, Maria|Scarpa, Aldo|van Tilborg, Angela A|Leenstra, Sieger|Zanon, Carlo|Bardelli, Alberto | ||||||||||
| PMID: | 17440062 | ||||||||||
| 3. | |||||||||||
| Journal: | Curr Drug Targets. 2013 Sep;14(10):1150-6. | ||||||||||
| Title: | Genistein down-regulates miR-223 expression in pancreatic cancer cells. | ||||||||||
| Author: | Ma, Jia|Cheng, Long|Liu, Hao|Zhang, Jing|Shi, Ying|Zeng, Fanpeng|Miele, Lucio|Sarkar, Fazlul H|Xia, Jun|Wang, Zhiwei | ||||||||||
| PMID: | 23834147 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncotarget. 2014 Jun 15;5(11):3444-54. | ||||||||||
| Title: | Nuclear retention of Fbw7 by specific inhibitors of nuclear export leads to Notch1 degradation in pancreatic cancer. | ||||||||||
| Author: | Gao, Jiankun|Azmi, Asfar S|Aboukameel, Amro|Kauffman, Michael|Shacham, Sharon|Abou-Samra, Abdul-Badi|Mohammad, Ramzi M | ||||||||||
| PMID: | 24899509 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncotarget. 2015 Mar 10;6(7):4553-61. | ||||||||||
| Title: | Molecular landscape of pancreatic cancer: implications for current clinical trials. | ||||||||||
| Author: | Heestand, Gregory M|Kurzrock, Razelle | ||||||||||
| PMID: | 11051691 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncotarget. 2015 Jan 30;6(3):1740-9. | ||||||||||
| Title: | Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. | ||||||||||
| Author: | Ma, Jia|Fang, Binbin|Zeng, Fanpeng|Ma, Cong|Pang, Haijie|Cheng, Long|Shi, Ying|Wang, Hui|Yin, Bin|Xia, Jun|Wang, Zhiwei | ||||||||||
| PMID: | 25638153 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncotarget. 2015 Mar 10;6(7):4553-61. | ||||||||||
| Title: | Molecular landscape of pancreatic cancer: implications for current clinical trials. | ||||||||||
| Author: | Heestand, Gregory M|Kurzrock, Razelle | ||||||||||
| PMID: | 25714017 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Res. 2015 May;25(5):561-73. | ||||||||||
| Title: | ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer. | ||||||||||
| Author: | Ji, Shunrong|Qin, Yi|Shi, Si|Liu, Xiangyuan|Hu, Hongli|Zhou, Hu|Gao, Jing|Zhang, Bo|Xu, Wenyan|Liu, Jiang|Liang, Dingkong|Liu, Liang|Liu, Chen|Long, Jiang|Zhou, Haijun|Chiao, Paul J|Xu, Jin|Ni, Quanxing|Gao, Daming|Yu, Xianjun | ||||||||||
| PMID: | 25753158 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Aug 1;22(15):3950-60. | ||||||||||
| Title: | FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer. | ||||||||||
| Author: | Ji, Shunrong|Qin, Yi|Liang, Chen|Huang, Run|Shi, Si|Liu, Jiang|Jin, Kaizhou|Liang, Dingkong|Xu, Wenyan|Zhang, Bo|Liu, Liang|Liu, Chen|Xu, Jin|Ni, Quanxing|Chiao, Paul J|Li, Min|Yu, Xianjun | ||||||||||
| PMID: | 26983463 | ||||||||||
| 10. | |||||||||||
| Journal: | Neoplasia. 2016 Nov;18(11):666-673. | ||||||||||
| Title: | Fbxw7 Deletion Accelerates Kras(G12D)-Driven Pancreatic Tumorigenesis via Yap Accumulation. | ||||||||||
| Author: | Zhang, Qiang|Zhang, Yaqing|Parsels, Joshua D|Lohse, Ines|Lawrence, Theodore S|Pasca di Magliano, Marina|Sun, Yi|Morgan, Meredith A | ||||||||||
| PMID: | 27764699 | ||||||||||
| 11. | |||||||||||
| Journal: | Tumour Biol. 2016 Oct;37(10):13893-13902. | ||||||||||
| Title: | Tumor suppressor Fbxw7 antagonizes WNT signaling by targeting beta-catenin for degradation in pancreatic cancer. | ||||||||||
| Author: | Jiang, Jian-Xin|Sun, Cheng-Yi|Tian, She|Yu, Chao|Chen, Mei-Yuan|Zhang, Hao | ||||||||||
| PMID: | 27485116 | ||||||||||
| 12. | |||||||||||
| Journal: | J Gastrointest Oncol. 2016 Apr;7(2):E6-E12. | ||||||||||
| Title: | Molecular profiling of a case of advanced pancreatic cancer identifies an active and tolerable combination of targeted therapy with backbone chemotherapy. | ||||||||||
| Author: | Johnson, Benny|Vanderwalde, Ari|Javadi, Nader|Feldman, Rebecca|Reddy, Sandeep Bobby | ||||||||||
| PMID: | 27034805 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncotarget. 2017 Feb 28;8(9):14620-14635. | ||||||||||
| Title: | Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture. | ||||||||||
| Author: | Xu, Meng-Dan|Liu, Shu-Ling|Feng, Yi-Zhong|Liu, Qiang|Shen, Meng|Zhi, Qiaoming|Liu, Zeyi|Gu, Dong-Mei|Yu, Jie|Shou, Liu-Mei|Gong, Fei-Ran|Zhu, Qi|Duan, Weiming|Chen, Kai|Zhang, Junning|Wu, Meng-Yao|Tao, Min|Li, Wei | ||||||||||
| PMID: | 28099906 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2017 Apr 14;292(15):6269-6280. | ||||||||||
| Title: | CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion. | ||||||||||
| Author: | Jin, Xin|Yang, Chong|Fan, Ping|Xiao, Jun|Zhang, Wanli|Zhan, Sudong|Liu, Tao|Wang, Dejie|Wu, Heshui | ||||||||||
| PMID: | 28242758 | ||||||||||
| 15. | |||||||||||
| Journal: | J Gastrointest Oncol. 2017 Feb;8(1):164-172. | ||||||||||
| Title: | Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. | ||||||||||
| Author: | Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K | ||||||||||
| PMID: | 28280620 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncol Rep. 2017 Oct;38(4):2069-2077. | ||||||||||
| Title: | FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1. | ||||||||||
| Author: | Hu, Qiangsheng|Qin, Yi|Zhang, Bo|Liang, Chen|Ji, Shunrong|Shi, Si|Xu, Wenyan|Xiang, Jinfeng|Liang, Dingkong|Ni, Quanxing|Yu, Xianjun|Xu, Jin | ||||||||||
| PMID: | 28765935 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 6;8(68):112636-112646. | ||||||||||
| Title: | Reduced FBXW7 expression in pancreatic cancer correlates with poor prognosis and chemotherapeutic resistance via accumulation of MCL1. | ||||||||||
| Author: | Ishii, Norihiro|Araki, Kenichiro|Yokobori, Takehiko|Gantumur, Dorgormaa|Yamanaka, Takahiro|Altan, Bolag|Tsukagoshi, Mariko|Igarashi, Takamichi|Watanabe, Akira|Kubo, Norio|Hosouchi, Yasuo|Kuwano, Hiroyuki|Shirabe, Ken | ||||||||||
| PMID: | 29348852 | ||||||||||