Literatures

Primary Site >> Colorectal Cancer

Gene >> FBXW7

1.
Journal:	Cell Cycle. 2004 Jun;3(6):693-4.
Title:	hCDC4 and genetic instability in cancer.
Author:	Rajagopalan, Harith\|Lengauer, Christoph
PMID:	15118416

2.
Journal:	Nature. 2004 Mar 4;428(6978):77-81.
Title:	Inactivation of hCDC4 can cause chromosomal instability.
Author:	Rajagopalan, Harith\|Jallepalli, Prasad V\|Rago, Carlo\|Velculescu, Victor E\|Kinzler, Kenneth W\|Vogelstein, Bert\|Lengauer, Christoph
PMID:	14999283

3.
Journal:	Cancer Res. 2005 Dec 15;65(24):11361-6.
Title:	CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
Author:	Kemp, Zoe\|Rowan, Andrew\|Chambers, William\|Wortham, Noel\|Halford, Sarah\|Sieber, Oliver\|Mortensen, Neil\|von Herbay, Axel\|Gunther, Thomas\|Ilyas, Mohammad\|Tomlinson, Ian
PMID:	16357143

4.
Journal:	Biochem Biophys Res Commun. 2007 Mar 23;354(4):992-8.
Title:	The FBXW7 beta-form is suppressed in human glioma cells.
Author:	Gu, Zhaodi\|Inomata, Kenichi\|Ishizawa, Kota\|Horii, Akira
PMID:	17274947

5.
Journal:	Cancer Res. 2007 Apr 15;67(8):3545-50.
Title:	Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma.
Author:	Balakrishnan, Asha\|Bleeker, Fonnet E\|Lamba, Simona\|Rodolfo, Monica\|Daniotti, Maria\|Scarpa, Aldo\|van Tilborg, Angela A\|Leenstra, Sieger\|Zanon, Carlo\|Bardelli, Alberto
PMID:	17440062

6.
Journal:	Cancer Biol Ther. 2007 Apr;6(4):525-33.
Title:	High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers.
Author:	Nishida, Naoshi\|Nagasaka, Takeshi\|Kashiwagi, Kazuhiro\|Boland, C Richard\|Goel, Ajay
PMID:	17457043

7.
Journal:	Oncology. 2009;76(6):430-4.
Title:	Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors.
Author:	Miyaki, Michiko\|Yamaguchi, Tatsuro\|Iijima, Takeru\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Mori, Takeo
PMID:	19420964

8.
Journal:	Int J Cancer. 2010 Apr 15;126(8):1828-37.
Title:	Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance.
Author:	Iwatsuki, Masaaki\|Mimori, Koshi\|Ishii, Hideshi\|Yokobori, Takehiko\|Takatsuno, Yasushi\|Sato, Tetsuya\|Toh, Hiroyuki\|Onoyama, Ichiro\|Nakayama, Keiichi I\|Baba, Hideo\|Mori, Masaki
PMID:	19739118

9.
Journal:	Gastroenterology. 2010 Sep;139(3):929-41.
Title:	F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Author:	Sancho, Rocio\|Jandke, Anett\|Davis, Hayley\|Diefenbacher, Markus E\|Tomlinson, Ian\|Behrens, Axel
PMID:	20638938

10.
Journal:	J Exp Med. 2011 Feb 14;208(2):295-312.
Title:	FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Author:	Babaei-Jadidi, Roya\|Li, Ningning\|Saadeddin, Anas\|Spencer-Dene, Bradley\|Jandke, Anett\|Muhammad, Belal\|Ibrahim, ElSayed E\|Muraleedharan, Ranjithmenon\|Abuzinadah, Mohammed\|Davis, Hayley\|Lewis, Annabelle\|Watson, Susan\|Behrens, Axel\|Tomlinson, Ian\|Nateri, Abdo
PMID:	21282377

11.
Journal:	Nature. 2011 Mar 3;471(7336):104-9.
Title:	SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Author:	Inuzuka, Hiroyuki\|Shaik, Shavali\|Onoyama, Ichiro\|Gao, Daming\|Tseng, Alan\|Maser, Richard S\|Zhai, Bo\|Wan, Lixin\|Gutierrez, Alejandro\|Lau, Alan W\|Xiao, Yonghong\|Christie, Amanda L\|Aster, Jon\|Settleman, Jeffrey\|Gygi, Steven P\|Kung, Andrew L\|Look, Thomas\|Nakay
PMID:	21368833

12.
Journal:	Biochem Biophys Res Commun. 2012 Feb 10;418(2):426-32.
Title:	Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
Author:	Guo, Zheng\|Zhou, Yuning\|Evers, B Mark\|Wang, Qingding
PMID:	22285861

13.
Journal:	Cancer Discov. 2012 Jun;2(6):540-53.
Title:	miR-23a promotes the transition from indolent to invasive colorectal cancer.
Author:	Jahid, Sohail\|Sun, Jian\|Edwards, Robert A\|Dizon, Diana\|Panarelli, Nicole C\|Milsom, Jeffrey W\|Sikandar, Shaheen S\|Gumus, Zeynep H\|Lipkin, Steven M
PMID:	22628407

14.
Journal:	Mol Cell Biol. 2012 Jun;32(11):2160-7.
Title:	Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
Author:	Grim, Jonathan E\|Knoblaugh, Sue E\|Guthrie, Katherine A\|Hagar, Amanda\|Swanger, Jherek\|Hespelt, Jessica\|Delrow, Jeffrey J\|Small, Tom\|Grady, William M\|Nakayama, Keiichi I\|Clurman, Bruce E
PMID:	22473991

15.
Journal:	Biochem Biophys Res Commun. 2013 May 3;434(2):352-6.
Title:	Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells.
Author:	Wang, Yuli\|Liu, Yueyong\|Lu, Jing\|Zhang, Pengju\|Wang, Yunshan\|Xu, Yangyang\|Wang, Zeran\|Mao, Jian-Hua\|Wei, Guangwei
PMID:	23558291

16.
Journal:	Mol Cell Biol. 2013 Sep;33(17):3494-504.
Title:	MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death.
Author:	Wong, Waihay J\|Qiu, Bo\|Nakazawa, Michael S\|Qing, Guoliang\|Simon, M Celeste
PMID:	23816886

17.
Journal:	Am J Gastroenterol. 2013 Nov;108(11):1785-93.
Title:	Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Author:	Mouradov, Dmitri\|Domingo, Enric\|Gibbs, Peter\|Jorissen, Robert N\|Li, Shan\|Soo, Pik Ying\|Lipton, Lara\|Desai, Jayesh\|Danielsen, Havard E\|Oukrif, Dahmane\|Novelli, Marco\|Yau, Christopher\|Holmes, Christopher C\|Jones, Ian T\|McLaughlin, Stephen\|Molloy, Peter\|Hawk
PMID:	24042191

18.
Journal:	Genomics. 2014 Oct;104(4):234-41.
Title:	Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing.
Author:	Xie, Tao\|Cho, Yong Beom\|Wang, Kai\|Huang, Donghui\|Hong, Hye Kyung\|Choi, Yoon-La\|Ko, Young Hyeh\|Nam, Do-Hyun\|Jin, Juyoun\|Yang, Heekyoung\|Fernandez, Julio\|Deng, Shibing\|Rejto, Paul A\|Lee, Woo Yong\|Mao, Mao
PMID:	25066378

19.
Journal:	Oncotarget. 2014 Oct 30;5(20):9641-9.
Title:	Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions.
Author:	Sakai, Kazuko\|Kazama, Shinsuke\|Nagai, Yuzo\|Murono, Koji\|Tanaka, Toshiaki\|Ishihara, Soichiro\|Sunami, Eiji\|Tomida, Shuta\|Nishio, Kazuto\|Watanabe, Toshiaki
PMID:	25275295

20.
Journal:	J Pathol. 2014 Dec;234(4):488-501.
Title:	Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma.
Author:	Li, Lihua\|Sarver, Aaron L\|Khatri, Rohini\|Hajeri, Praveensingh B\|Kamenev, Iris\|French, Amy J\|Thibodeau, Stephen N\|Steer, Clifford J\|Subramanian, Subbaya
PMID:	25269767

21.
Journal:	Cancer Causes Control. 2014 Jun;25(6):759-69.
Title:	Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.
Author:	Huhn, Stefanie\|Bevier, Melanie\|Pardini, Barbara\|Naccarati, Alessio\|Vodickova, Ludmila\|Novotny, Jan\|Vodicka, Pavel\|Hemminki, Kari\|Forsti, Asta
PMID:	24706189

22.
Journal:	PLoS One. 2014 Feb 19;9(2):e89388.
Title:	FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
Author:	Jardim, Denis L\|Wheler, Jennifer J\|Hess, Kenneth\|Tsimberidou, Apostolia M\|Zinner, Ralph\|Janku, Filip\|Subbiah, Vivek\|Naing, Aung\|Piha-Paul, Sarina A\|Westin, Shannon N\|Roy-Chowdhuri, Sinchita\|Meric-Bernstam, Funda\|Hong, David S
PMID:	24586741

23.
Journal:	J Biol Chem. 2014 Feb 28;289(9):5997-6005.
Title:	A colon cancer-derived mutant of Kruppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3beta (GSK3beta) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7alpha (FBW7alpha).
Author:	Bialkowska, Agnieszka B\|Liu, Yang\|Nandan, Mandayam O\|Yang, Vincent W
PMID:	24398687

24.
Journal:	Gut. 2014 May;63(5):792-9.
Title:	Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.
Author:	Davis, Hayley\|Lewis, Annabelle\|Behrens, Axel\|Tomlinson, Ian
PMID:	23676439

25.
Journal:	Clin Cancer Res. 2014 Jan 1;20(1):265-72.
Title:	Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Author:	Guinney, Justin\|Ferte, Charles\|Dry, Jonathan\|McEwen, Robert\|Manceau, Gilles\|Kao, K J\|Chang, Kai-Ming\|Bendtsen, Claus\|Hudson, Kevin\|Huang, Erich\|Dougherty, Brian\|Ducreux, Michel\|Soria, Jean-Charles\|Friend, Stephen\|Derry, Jonathan\|Laurent-Puig, Pierre
PMID:	24170544

26.
Journal:	Gut. 2014 May;63(5):707-9.
Title:	Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models.
Author:	Grim, Jonathan E
PMID:	24000292

27.
Journal:	PLoS One. 2014 Jan 27;9(1):e82185.
Title:	An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Author:	Brim, Hassan\|Abu-Asab, Mones S\|Nouraie, Mehdi\|Salazar, Jose\|Deleo, Jim\|Razjouyan, Hadi\|Mokarram, Pooneh\|Schaffer, Alejandro A\|Naghibhossaini, Fakhraddin\|Ashktorab, Hassan
PMID:	24475022

28.
Journal:	Lab Invest. 2015 Sep;95(9):995-1004.
Title:	FBXW7 negatively regulates ENO1 expression and function in colorectal cancer.
Author:	Zhan, Panpan\|Wang, Yuli\|Zhao, Shihu\|Liu, Chunyan\|Wang, Yunshan\|Wen, Mingxin\|Mao, Jian-Hua\|Wei, Guangwei\|Zhang, Pengju
PMID:	26097998

29.
Journal:	Rinsho Byori. 2015 Sep;63(9):1091-102.
Title:	[Alternative Splicing Detection as a Biomarker for Cancer Diagnosis: A Novel Progressive Mechanism of Acute Lymphoblastic Leukemia with Alternative Splicing as a Biomarker Candidate].
Author:	Kitamura, Kouichi\|Matsushita, Kazuyuki\|Kobayashi, Souhei\|Ishige, Takayuki\|Semba, Toshihisa\|Kimura, Asako\|Kazami, Takahiro\|Ohyama, Masayuki\|Itoga, Sakae\|Beppu, Minako\|Nishimura, Motoi\|Satoh, Mamoru\|Nomura, Fumio
PMID:	26731899

30.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

31.
Journal:	PLoS One. 2015 Sep 16;10(9):e0138141.
Title:	High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.
Author:	van den Broek, Evert\|Dijkstra, Maurits J J\|Krijgsman, Oscar\|Sie, Daoud\|Haan, Josien C\|Traets, Joleen J H\|van de Wiel, Mark A\|Nagtegaal, Iris D\|Punt, Cornelis J A\|Carvalho, Beatriz\|Ylstra, Bauke\|Abeln, Sanne\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	26375816

32.
Journal:	J Hum Genet. 2015 Oct;60(10):589-96.
Title:	Genetic mutations in human rectal cancers detected by targeted sequencing.
Author:	Bai, Jun\|Gao, Jinglong\|Mao, Zhijun\|Wang, Jianhua\|Li, Jianhui\|Li, Wensheng\|Lei, Yu\|Li, Shuaishuai\|Wu, Zhuo\|Tang, Chuanning\|Jones, Lindsey\|Ye, Hua\|Lou, Feng\|Liu, Zhiyuan\|Dong, Zhishou\|Guo, Baishuai\|Huang, Xue F\|Chen, Si-Yi\|Zhang, Enke
PMID:	26134512

33.
Journal:	PLoS One. 2015 May 14;10(5):e0126670.
Title:	Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.
Author:	Kim, Richard\|Schell, Michael J\|Teer, Jamie K\|Greenawalt, Danielle M\|Yang, Mingli\|Yeatman, Timothy J
PMID:	25974029

34.
Journal:	Oncotarget. 2015 Apr 20;6(11):9240-56.
Title:	FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15.
Author:	Li, Ningning\|Lorenzi, Federica\|Kalakouti, Eliana\|Normatova, Makhliyo\|Babaei-Jadidi, Roya\|Tomlinson, Ian\|Nateri, Abdolrahman S
PMID:	25860929

35.
Journal:	Mol Cancer Ther. 2015 Jun;14(6):1476-87.
Title:	Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.
Author:	Fang, Lekun\|Yang, Zihuan\|Zhou, Junyi\|Tung, Jung-Yu\|Hsiao, Chwan-Deng\|Wang, Lei\|Deng, Yanhong\|Wang, Puning\|Wang, Jianping\|Lee, Mong-Hong
PMID:	25855785

36.
Journal:	Am J Surg Pathol. 2015 Aug;39(8):1140-7.
Title:	Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.
Author:	Jesinghaus, Moritz\|Wolf, Thomas\|Pfarr, Nicole\|Muckenhuber, Alexander\|Ahadova, Aysel\|Warth, Arne\|Goeppert, Benjamin\|Sers, Christine\|Kloor, Matthias\|Endris, Volker\|Stenzinger, Albrecht\|Weichert, Wilko
PMID:	25786087

37.
Journal:	Biochem Biophys Res Commun. 2015 Feb 27;458(1):52-6.
Title:	Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.
Author:	Kogita, Akihiro\|Yoshioka, Yasumasa\|Sakai, Kazuko\|Togashi, Yosuke\|Sogabe, Shunsuke\|Nakai, Takuya\|Okuno, Kiyotaka\|Nishio, Kazuto
PMID:	25623536

38.
Journal:	Int J Mol Sci. 2015 Jan 22;16(2):2294-306.
Title:	FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma.
Author:	Li, Zhanchun\|Xiao, Jie\|Hu, Kongzu\|Wang, Gang\|Li, Maoqiang\|Zhang, Jidong\|Cheng, Guangqi
PMID:	25622249

39.
Journal:	PLoS One. 2015 Jan 24;10(1):e0116753.
Title:	A pathway-centric survey of somatic mutations in Chinese patients with colorectal carcinomas.
Author:	Ling, Chao\|Wang, Lin\|Wang, Zheng\|Xu, Luming\|Sun, Lifang\|Yang, Hui\|Li, Wei-Dong\|Wang, Kai
PMID:	25617745

40.
Journal:	Int J Biol Markers. 2015 Feb 24;30(1):e88-95.
Title:	FBXW7 mutation analysis and its correlation with clinicopathological features and prognosis in colorectal cancer patients.
Author:	Chang, Chia-Chu\|Lin, Hung-Hsin\|Lin, Jen-Kou\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Jiang, Jeng-Kai\|Chang, Shih-Ching
PMID:	25450649

41.
Journal:	Mol Oncol. 2016 Dec;10(10):1575-1584.
Title:	Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases.
Author:	Beije, Nick\|Helmijr, Jean C\|Weerts, Marjolein J A\|Beaufort, Corine M\|Wiggin, Matthew\|Marziali, Andre\|Verhoef, Cornelis\|Sleijfer, Stefan\|Jansen, Maurice P H M\|Martens, John W M
PMID:	28949453

42.
Journal:	J Gastrointest Oncol. 2016 Dec;7(6):882-902.
Title:	Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Author:	Al-Shamsi, Humaid O\|Jones, Jeremy\|Fahmawi, Yazan\|Dahbour, Ibrahim\|Tabash, Aziz\|Abdel-Wahab, Reham\|Abousamra, Ahmed O S\|Shaw, Kenna R\|Xiao, Lianchun\|Hassan, Manal M\|Kipp, Benjamin R\|Kopetz, Scott\|Soliman, Amr S\|McWilliams, Robert R\|Wolff, Robert A
PMID:	28078112

43.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

44.
Journal:	Oncotarget. 2016 Nov 8;7(45):73876-73887.
Title:	Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.
Author:	van den Broek, Evert\|Krijgsman, Oscar\|Sie, Daoud\|Tijssen, Marianne\|Mongera, Sandra\|van de Wiel, Mark A\|Belt, Eric J Th\|den Uil, Sjoerd H\|Bril, Herman\|Stockmann, Hein B A C\|Ylstra, Bauke\|Carvalho, Beatriz\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	27729614

45.
Journal:	Med Oncol. 2016 Oct;33(10):106.
Title:	Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Shokeen, Yogender\|Minhas, Sachin\|Aggarwal, Shyam
PMID:	27568332

46.
Journal:	Cancer Prev Res (Phila). 2016 Jun;9(6):417-27.
Title:	Genomic Landscape of Colorectal Mucosa and Adenomas.
Author:	Borras, Ester\|San Lucas, F Anthony\|Chang, Kyle\|Zhou, Ruoji\|Masand, Gita\|Fowler, Jerry\|Mork, Maureen E\|You, Y Nancy\|Taggart, Melissa W\|McAllister, Florencia\|Jones, David A\|Davies, Gareth E\|Edelmann, Winfried\|Ehli, Erik A\|Lynch, Patrick M\|Hawk, Ernest T\|Cap
PMID:	27221540

47.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

48.
Journal:	Mol Cancer Res. 2016 Nov;14(11):1097-1109.
Title:	Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3beta-Dependent Manner.
Author:	Kumar, Yogesh\|Shukla, Nidhi\|Thacker, Gatha\|Kapoor, Isha\|Lochab, Savita\|Bhatt, Madan Lal Brahma\|Chattopadhyay, Naibedya\|Sanyal, Sabyasachi\|Trivedi, Arun Kumar
PMID:	27470268

49.
Journal:	Sci Rep. 2016 Jul 15;6:29869.
Title:	Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.
Author:	Bi, Haoran\|Tian, Tian\|Zhu, Lin\|Zhou, Haibo\|Hu, Hanqing\|Liu, Yanhong\|Li, Xia\|Hu, Fulan\|Zhao, Yashuang\|Wang, Guiyu
PMID:	27417709

50.
Journal:	Cancer. 2016 Sep 15;122(18):2828-35.
Title:	Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.
Author:	Kothari, Nishi\|Teer, Jamie K\|Abbott, Andrea M\|Srikumar, Thejal\|Zhang, Yonghong\|Yoder, Sean J\|Brohl, Andrew S\|Kim, Richard D\|Reed, Damon R\|Shibata, David
PMID:	27244218

51.
Journal:	J Mol Diagn. 2016 Jul;18(4):471-9.
Title:	Driver Gene Mutations in Stools of Colorectal Carcinoma Patients Detected by Targeted Next-Generation Sequencing.
Author:	Armengol, Gemma\|Sarhadi, Virinder K\|Ghanbari, Reza\|Doghaei-Moghaddam, Masoud\|Ansari, Reza\|Sotoudeh, Masoud\|Puolakkainen, Pauli\|Kokkola, Arto\|Malekzadeh, Reza\|Knuutila, Sakari
PMID:	27155048

52.
Journal:	J Transl Med. 2016 May 4;14(1):118.
Title:	Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.
Author:	Dallol, Ashraf\|Buhmeida, Abdelbaset\|Al-Ahwal, Mahmoud Shaheen\|Al-Maghrabi, Jaudah\|Bajouh, Osama\|Al-Khayyat, Shadi\|Alam, Rania\|Abusanad, Atlal\|Turki, Rola\|Elaimi, Aisha\|Alhadrami, Hani A\|Abuzenadah, Mohammed\|Banni, Huda\|Al-Qahtani, Mohammed H\|Abuzenadah, A
PMID:	27146902

53.
Journal:	Mol Ther Methods Clin Dev. 2016 Apr 13;3:16024.
Title:	Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.
Author:	Lorenzi, Federica\|Babaei-Jadidi, Roya\|Sheard, Jonathan\|Spencer-Dene, Bradley\|Nateri, Abdolrahman S
PMID:	27110583

54.
Journal:	J Clin Pathol. 2016 Sep;69(9):767-71.
Title:	Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author:	Malapelle, Umberto\|Pisapia, Pasquale\|Sgariglia, Roberta\|Vigliar, Elena\|Biglietto, Maria\|Carlomagno, Chiara\|Giuffre, Giuseppe\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	26797410

55.
Journal:	Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title:	Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author:	Crumley, Suzanne M\|Pepper, Kristi L\|Phan, Alexandria T\|Olsen, Randall J\|Schwartz, Mary R\|Portier, Bryce P
PMID:	26536055

56.
Journal:	Cancer Lett. 2016 Oct 1;380(2):457-66.
Title:	Plk2 promotes tumor growth and inhibits apoptosis by targeting Fbxw7/Cyclin E in colorectal cancer.
Author:	Ou, Baochi\|Zhao, Jingkun\|Guan, Shaopei\|Wangpu, Xiongzhi\|Zhu, Congcong\|Zong, Yaping\|Ma, Junjun\|Sun, Jing\|Zheng, Minhua\|Feng, Hao\|Lu, Aiguo
PMID:	27423313

57.
Journal:	Oncotarget. 2017 Aug 21;8(42):72352-72362.
Title:	Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer.
Author:	Chang, Pi-Yueh\|Chen, Jinn-Shiun\|Chang, Shih-Cheng\|Wang, Mei-Chia\|Chang, Nai-Chung\|Wen, Ying-Hao\|Tsai, Wen-Sy\|Liu, Wei-Hsiu\|Liu, Hsiu-Ling\|Lu, Jang-Jih
PMID:	29069792

58.
Journal:	Clin Transl Gastroenterol. 2017 Oct 19;8(10):e124.
Title:	Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer.
Author:	Staudacher, Jonas J\|Yazici, Cemal\|Bul, Vadim\|Zeidan, Joseph\|Khalid, Ahmer\|Xia, Yinglin\|Krett, Nancy\|Jung, Barbara
PMID:	29048416

59.
Journal:	Oncotarget. 2017 Jul 10;8(40):68026-68037.
Title:	Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Author:	Kong, Say Li\|Liu, Xingliang\|Suhaimi, Nur-Afidah Mohamed\|Koh, Kenneth Jia Hao\|Hu, Min\|Lee, Daniel Yoke San\|Cima, Igor\|Phyo, Wai Min\|Lee, Esther Xing Wei\|Tai, Joyce A\|Foong, Yu Miin\|Vo, Jess Honganh\|Koh, Poh Koon\|Zhang, Tong\|Ying, Jackie Y\|Lim, Bing\|Tan, Mi
PMID:	28978093

60.
Journal:	Stem Cells. 2017 Sep;35(9):2027-2036.
Title:	Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F-Box/WD Repeat-Containing Protein 7 and the Consequent Degradation of c-Myc.
Author:	Izumi, Daisuke\|Ishimoto, Takatsugu\|Miyake, Keisuke\|Eto, Tsugio\|Arima, Kota\|Kiyozumi, Yuki\|Uchihara, Tomoyuki\|Kurashige, Junji\|Iwatsuki, Masaaki\|Baba, Yoshifumi\|Sakamoto, Yasuo\|Miyamoto, Yuji\|Yoshida, Naoya\|Watanabe, Masayuki\|Goel, Ajay\|Tan, Patrick\|Baba,
PMID:	28699179

61.
Journal:	Mol Clin Oncol. 2017 Jul;7(1):113-120.
Title:	Heterogeneity in the colorectal primary tumor and the synchronous resected liver metastases prior to and after treatment with an anti-EGFR monoclonal antibody.
Author:	Adua, Daniela\|Di Fabio, Francesca\|Ercolani, Giorgio\|Fiorentino, Michelangelo\|Gruppioni, Elisa\|Altimari, Annalisa\|Rojas Limpe, Fabiola Lorena\|Normanno, Nicola\|Pinna, Antonio Daniele\|Pinto, Carmine
PMID:	28685087

62.
Journal:	Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title:	Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author:	Chang, Chu-Cheng\|Lin, Pei-Ching\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Lin, Hung-Hsin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	28678173

63.
Journal:	Mol Cancer Ther. 2017 Sep;16(9):1979-1988.
Title:	FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors.
Author:	Tong, Jingshan\|Tan, Shuai\|Nikolovska-Coleska, Zaneta\|Yu, Jian\|Zou, Fangdong\|Zhang, Lin
PMID:	28619760

64.
Journal:	Biomed Pharmacother. 2017 Jun;90:548-554.
Title:	FAM83D knockdown regulates proliferation, migration and invasion of colorectal cancer through inhibiting FBXW7/Notch-1 signalling pathway.
Author:	Mu, Yu\|Zou, Hongzhi\|Chen, Beibei\|Fan, Yixiao\|Luo, Suxia
PMID:	28407575

65.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

66.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

67.
Journal:	Cancer Res. 2017 May 1;77(9):2512-2521.
Title:	Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.
Author:	Tong, Jingshan\|Wang, Peng\|Tan, Shuai\|Chen, Dongshi\|Nikolovska-Coleska, Zaneta\|Zou, Fangdong\|Yu, Jian\|Zhang, Lin
PMID:	28202514

68.
Journal:	Gut. 2017 Dec;66(12):2132-2140.
Title:	Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Author:	Sievers, Chelsie K\|Zou, Luli S\|Pickhardt, Perry J\|Matkowskyj, Kristina A\|Albrecht, Dawn M\|Clipson, Linda\|Bacher, Jeffery W\|Pooler, B Dustin\|Moawad, Fouad J\|Cash, Brooks D\|Reichelderfer, Mark\|Vo, Tien N\|Newton, Michael A\|Larget, Bret R\|Halberg, Richard B
PMID:	27609830

69.
Journal:	Oncogene. 2017 Feb 9;36(6):787-796.
Title:	FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
Author:	Tong, J\|Tan, S\|Zou, F\|Yu, J\|Zhang, L
PMID:	27399335

70.
Journal:	Oncotarget. 2017 Jun 13;8(24):39268-39279.
Title:	FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.
Author:	Korphaisarn, Krittiya\|Morris, Van Karlyle\|Overman, Michael J\|Fogelman, David R\|Kee, Bryan K\|Raghav, Kanwal Pratap Singh\|Manuel, Shanequa\|Shureiqi, Imad\|Wolff, Robert A\|Eng, Cathy\|Menter, David\|Hamilton, Stanley R\|Kopetz, Scott\|Dasari, Arvind
PMID:	28424412

71.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):597-604.
Title:	MiR-223 promotes the doxorubicin resistance of colorectal cancer cells via regulating epithelial-mesenchymal transition by targeting FBXW7.
Author:	Ding, Jieqiong\|Zhao, Zhiwei\|Song, Jia\|Luo, Binghua\|Huang, Lingping
PMID:	29701752

72.
Journal:	Oncogenesis. 2018 Jul 22;7(7):55.
Title:	Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer.
Author:	De Nicola, Francesca\|Goeman, Frauke\|Pallocca, Matteo\|Sperati, Francesca\|Pizzuti, Laura\|Melucci, Elisa\|Casini, Beatrice\|Amoreo, Carla Azzurra\|Gallo, Enzo\|Diodoro, Maria Grazia\|Buglioni, Simonetta\|Mazzotta, Marco\|Vici, Patrizia\|Sergi, Domenico\|Di Lauro, Lui
PMID:	30032163

73.
Journal:	Virchows Arch. 2018 Jun;472(6):959-968.
Title:	Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Author:	Wang, Yajian\|Liu, Haijing\|Hou, Yingyong\|Zhou, Xiaoyan\|Liang, Li\|Zhang, Zhihong\|Shi, Huaiyin\|Xu, Sanpeng\|Hu, Peizhen\|Zheng, Zuyu\|Liu, Rui\|Tang, Tingdong\|Ye, Feng\|Liang, Zhiyong\|Bu, Hong
PMID:	29705968

74.
Journal:	Proc Natl Acad Sci U S A. 2018 May 22;115(21):5462-5467.
Title:	Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Author:	Davis, Ryan J\|Gonen, Mehmet\|Margineantu, Daciana H\|Handeli, Shlomo\|Swanger, Jherek\|Hoellerbauer, Pia\|Paddison, Patrick J\|Gu, Haiwei\|Raftery, Daniel\|Grim, Jonathan E\|Hockenbery, David M\|Margolin, Adam A\|Clurman, Bruce E
PMID:	29735700

75.
Journal:	Oncotarget. 2018 Apr 17;9(29):20426-20438.
Title:	Hotspot KRAS exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells.
Author:	Wong, Hung Lai\|Ng, Lawrence Po Wah\|Koh, Su Pin\|Chan, Lawrence Wing Chi\|Wong, Evelyn Yin Kwan\|Xue, Vivian Weiwen\|Tsang, Hin Fung Andy\|Chan, Amanda Kit Ching\|Chiu, Ka Yue\|Cheuk, Wah\|Wong, Sze Chuen Cesar
PMID:	29755662

76.
Journal:	Gynecol Oncol. 2018 Jul;150(1):127-135.
Title:	Massively parallel sequencing analysis of mucinous ovarian carcinomas: genomic profiling and differential diagnoses.
Author:	Mueller, Jennifer J\|Schlappe, Brooke A\|Kumar, Rahul\|Olvera, Narciso\|Dao, Fanny\|Abu-Rustum, Nadeem\|Aghajanian, Carol\|DeLair, Deborah\|Hussein, Yaser R\|Soslow, Robert A\|Levine, Douglas A\|Weigelt, Britta
PMID:	29793804

77.
Journal:	Int J Biol Sci. 2018 May 12;14(7):726-735.
Title:	FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1alpha/CEACAM5 functional axis.
Author:	Li, Qingguo\|Li, Yaqi\|Li, Jing\|Ma, Yanlei\|Dai, Weixing\|Mo, Shaobo\|Xu, Ye\|Li, Xinxiang\|Cai, Sanjun
PMID:	29910683

78.
Journal:	Oncotarget. 2018 Jun 8;9(44):27412-27422.
Title:	The landscape of somatic mutation in sporadic Chinese colorectal cancer.
Author:	Liu, Zhe\|Yang, Chao\|Li, Xiangchun\|Luo, Wen\|Roy, Bhaskar\|Xiong, Teng\|Zhang, Xiuqing\|Yang, Huanming\|Wang, Jian\|Ye, Zhenhao\|Chen, Yang\|Song, Jinghe\|Ma, Shuai\|Zhou, Yong\|Yang, Min\|Fang, Xiaodong\|Du, Jie
PMID:	29937994

79.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

80.
Journal:	World J Surg Oncol. 2018 Jul 5;16(1):128.
Title:	Differences in gene mutations according to gender among patients with colorectal cancer.
Author:	Tsai, Yi-Jian\|Huang, Sheng-Chieh\|Lin, Hung-Hsin\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	29976257

81.
Journal:	DNA Cell Biol. 2018 May;37(5):501-511.
Title:	miR-92b-3p Promotes Colorectal Carcinoma Cell Proliferation, Invasion, and Migration by Inhibiting FBXW7 In Vitro and In Vivo.
Author:	Gong, Lei\|Ren, Mingyang\|Lv, Zhenbing\|Yang, Yuling\|Wang, Ziwei
PMID:	29638162

82.
Journal:	Oncogene. 2018 Jul;37(27):3715-3728.
Title:	Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3beta and F-box and WD repeat domain-containing 7.
Author:	Jung, Ji Hoon\|Jung, Deok-Beom\|Kim, Hyunseok\|Lee, Hyemin\|Kang, Shi-Eun\|Srivastava, Sanjay K\|Yun, Miyong\|Kim, Sung-Hoon
PMID:	29628506

83.
Journal:	Biochem Biophys Res Commun. 2018 Apr 15;498(4):869-876.
Title:	Genetic Deletion of Fbw7 in the mouse intestinal epithelium aggravated dextran sodium sulfate-induced colitis by modulating the inflammatory response of NF-kappaB pathway.
Author:	Li, Huichen\|Liang, Ye\|Lai, Xiaofeng\|Wang, Weidong\|Zhang, Jiang\|Chen, Suning
PMID:	29550488

84.
Journal:	United European Gastroenterol J. 2018 Mar;6(2):290-299.
Title:	Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
Author:	Berger, Andreas W\|Raedler, Katja\|Langner, Cord\|Ludwig, Leopold\|Dikopoulos, Nektarios\|Becker, Karl F\|Slotta-Huspenina, Julia\|Quante, Michael\|Schwerdel, Daniel\|Perkhofer, Lukas\|Kleger, Alexander\|Zizer, Eugen\|Oswald, Franz\|Seufferlein, Thomas\|Meining, Alexan
PMID:	29511559

85.
Journal:	Sci Rep. 2018 Feb 16;8(1):3161.
Title:	Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations.
Author:	Druliner, Brooke R\|Wang, Panwen\|Bae, Taejeong\|Baheti, Saurabh\|Slettedahl, Seth\|Mahoney, Douglas\|Vasmatzis, Nikolaos\|Xu, Hang\|Kim, Minsoo\|Bockol, Matthew\|O'Brien, Daniel\|Grill, Diane\|Warner, Nathaniel\|Munoz-Gomez, Miguel\|Kossick, Kimberlee\|Johnson, Ruth\|Mo
PMID:	29453410

86.
Journal:	J Clin Oncol. 2018 May 1;36(13):1291-1299.
Title:	Phosphatidylinositol 3-Kinase alpha-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.
Author:	Juric, Dejan\|Rodon, Jordi\|Tabernero, Josep\|Janku, Filip\|Burris, Howard A\|Schellens, Jan H M\|Middleton, Mark R\|Berlin, Jordan\|Schuler, Martin\|Gil-Martin, Marta\|Rugo, Hope S\|Seggewiss-Bernhardt, Ruth\|Huang, Alan\|Bootle, Douglas\|Demanse, David\|Blumenstein, L
PMID:	29401002

87.
Journal:	J Clin Invest. 2018 Apr 2;128(4):1326-1337.
Title:	The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.
Author:	Khan, Omar M\|Carvalho, Joana\|Spencer-Dene, Bradley\|Mitter, Richard\|Frith, David\|Snijders, Ambrosius P\|Wood, Stephen A\|Behrens, Axel
PMID:	29346117

88.
Journal:	Cancer Res. 2018 Mar 1;78(5):1334-1346.
Title:	Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Author:	Sakai, Eri\|Nakayama, Mizuho\|Oshima, Hiroko\|Kouyama, Yuta\|Niida, Atsushi\|Fujii, Satoshi\|Ochiai, Atsushi\|Nakayama, Keiichi I\|Mimori, Koshi\|Suzuki, Yutaka\|Hong, Chang Pyo\|Ock, Chan-Young\|Kim, Seong-Jin\|Oshima, Masanobu
PMID:	29282223

89.
Journal:	Cancer. 2018 Mar 1;124(5):1070-1082.
Title:	A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.
Author:	Tricoli, James V\|Boardman, Lisa A\|Patidar, Rajesh\|Sindiri, Sivasish\|Jang, Jin S\|Walsh, William D\|McGregor, Paul M 3rd\|Camalier, Corinne E\|Mehaffey, Michele G\|Furman, Wayne L\|Bahrami, Armita\|Williams, P Mickey\|Lih, Chih-Jian\|Conley, Barbara A\|Khan, Javed
PMID:	29194591

90.
Journal:	Cancer Discov. 2018 Jan;8(1):108-125.
Title:	Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.
Author:	Zhang, Xiaoyang\|Choi, Peter S\|Francis, Joshua M\|Gao, Galen F\|Campbell, Joshua D\|Ramachandran, Aruna\|Mitsuishi, Yoichiro\|Ha, Gavin\|Shih, Juliann\|Vazquez, Francisca\|Tsherniak, Aviad\|Taylor, Alison M\|Zhou, Jin\|Wu, Zhong\|Berger, Ashton C\|Giannakis, Marios\|Hah
PMID:	28963353