Primary Site >> Pancreatic Cancer

Gene >> FASN

Journal: Anticancer Res. 2007 Jul-Aug;27(4B):2523-7.
Title: Immunohistochemical expression and prognostic significance of fatty acid synthase in pancreatic carcinoma.
Author: Alo, Piero L|Amini, Mostafa|Piro, Francesca|Pizzuti, Laura|Sebastiani, Valeria|Botti, Claudio|Murari, Riccardo|Zotti, Giancarlo|Di Tondo, Ugo
PMID: 17695548
Journal: Cell Cycle. 2008 Oct;7(19):3021-5. Epub 2008 Oct 23.
Title: Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome.
Author: Witkiewicz, Agnieszka K|Nguyen, Katherine H|Dasgupta, Abhijit|Kennedy, Eugene P|Yeo, Charles J|Lisanti, Michael P|Brody, Jonathan R
PMID: 18802406
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2380-5.
Title: Serum fatty acid synthase as a marker of pancreatic neoplasia.
Author: Walter, Kim|Hong, Seung-Mo|Nyhan, Sinead|Canto, Marcia|Fedarko, Neal|Klein, Alison|Griffith, Margaret|Omura, Noriyuki|Medghalchi, Susan|Kuhajda, Frank|Goggins, Michael
PMID: 19723916
Journal: Int J Biochem Mol Biol. 2011 Jan 1;2(1):89-98.
Title: Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers.
Author: Yang, Youyun|Liu, Hailan|Li, Zhaomin|Zhao, Zijin|Yip-Schneider, Michelle|Fan, Qipeng|Schmidt, C Max|Chiorean, E Gabriela|Xie, Jingwu|Cheng, Liang|Chen, Jey-Hsin|Zhang, Jian-Ting
PMID: 21331354
Journal: Tumour Biol. 2014 Apr;35(4):3855-9.
Title: Fatty acid synthase (FASN) levels in serum of colorectal cancer patients: correlation with clinical outcomes.
Author: Long, Qi-qiang|Yi, Yong-xiang|Qiu, Jie|Xu, Chuan-jun|Huang, Pei-lin
PMID: 24430360
Journal: World J Gastroenterol. 2014 Mar 7;20(9):2279-303.
Title: Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.
Author: Swierczynski, Julian|Hebanowska, Areta|Sledzinski, Tomasz
PMID: 24605027
Journal: Br J Cancer. 2014 Sep 9;111(6):1139-49.
Title: Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.
Author: Souchek, J J|Baine, M J|Lin, C|Rachagani, S|Gupta, S|Kaur, S|Lester, K|Zheng, D|Chen, S|Smith, L|Lazenby, A|Johansson, S L|Jain, M|Batra, S K
PMID: 25025965
Journal: Sci Rep. 2014 Oct 29;4:6807.
Title: Direct visualization of de novo lipogenesis in single living cells.
Author: Li, Junjie|Cheng, Ji-Xin
PMID: 25351207
Journal: Tumour Biol. 2015 Jun;36(6):4133-41.
Title: SREBP1 regulates tumorigenesis and prognosis of pancreatic cancer through targeting lipid metabolism.
Author: Sun, Yan|He, Weiwei|Luo, Man|Zhou, Yuhong|Chang, Guilin|Ren, Weiying|Wu, Kefen|Li, Xi|Shen, Jiping|Zhao, Xiaoping|Hu, Yu
PMID: 25589463
Journal: Biochem Biophys Res Commun. 2015 Aug 7;463(4):612-7.
Title: Up-regulation of fatty acid synthase induced by EGFR/ERK activation promotes tumor growth in pancreatic cancer.
Author: Bian, Yong|Yu, Yun|Wang, Shanshan|Li, Lin
PMID: 26043686
Journal: Oncotarget. 2015 Aug 28;6(25):20993-1003.
Title: Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis.
Author: Ma, Jiguang|Duan, Wanxing|Han, Suxia|Lei, Jianjun|Xu, Qinhong|Chen, Xin|Jiang, Zhengdong|Nan, Ligang|Li, Jiahui|Chen, Ke|Han, Liang|Wang, Zheng|Li, Xuqi|Wu, Erxi|Huo, Xiongwei
PMID: 25895130
Journal: Anticancer Res. 2016 Sep;36(9):4655-60.
Title: Inhibition of Fatty Acid Synthesis Induces Apoptosis of Human Pancreatic Cancer Cells.
Author: Nishi, Koji|Suzuki, Kenta|Sawamoto, Junpei|Tokizawa, Yuma|Iwase, Yumiko|Yumita, Nagahiko|Ikeda, Toshihiko
PMID: 27630308
Journal: EBioMedicine. 2017 Feb;16:51-62.
Title: FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Ex
Author: Heuer, Timothy S|Ventura, Richard|Mordec, Kasia|Lai, Julie|Fridlib, Marina|Buckley, Douglas|Kemble, George
PMID: 28159572
Journal: Biochem Biophys Res Commun. 2017 Jun 17;488(1):136-140.
Title: Sterol regulatory element-binding protein 1 inhibitors decrease pancreatic cancer cell viability and proliferation.
Author: Siqingaowa|Sekar, Sathiya|Gopalakrishnan, Venkat|Taghibiglou, Changiz
PMID: 28483521
Journal: Cancer Res. 2017 Oct 15;77(20):5503-5517.
Title: De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer.
Author: Tadros, Saber|Shukla, Surendra K|King, Ryan J|Gunda, Venugopal|Vernucci, Enza|Abrego, Jaime|Chaika, Nina V|Yu, Fang|Lazenby, Audrey J|Berim, Lyudmyla|Grem, Jean|Sasson, Aaron R|Singh, Pankaj K
PMID: 28811332
Journal: Anticancer Res. 2017 Nov;37(11):6321-6327.
Title: Orlistat Reduces Proliferation and Enhances Apoptosis in Human Pancreatic Cancer Cells (PANC-1).
Author: Sokolowska, Ewa|Presler, Malgorzata|Goyke, Elzbieta|Milczarek, Ryszard|Swierczynski, Julian|Sledzinski, Tomasz
PMID: 29061815
Journal: Oncol Lett. 2018 Feb;15(2):2211-2217.
Title: Upregulation of pyruvate kinase M2 expression by fatty acid synthase contributes to gemcitabine resistance in pancreatic cancer.
Author: Tian, Shenghua|Li, Pingping|Sheng, Shi|Jin, Xin
PMID: 29434927