Primary Site >> Pancreatic Cancer
Gene >> FASN
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Ref: Immunohistochemical expression and prognostic significance of fatty acid synthase in pancreatic carcinoma. PMID: 17695548 |
Ref: Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome. PMID: 18802406 |
Ref: Serum fatty acid synthase as a marker of pancreatic neoplasia. PMID: 19723916 |
Ref: Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers. PMID: 21331354 |
Ref: Fatty acid synthase (FASN) levels in serum of colorectal cancer patients: correlation with clinical outcomes. PMID: 24430360 Ref: Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer. PMID: 24605027 Ref: Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation. PMID: 25025965 Ref: Direct visualization of de novo lipogenesis in single living cells. PMID: 25351207 |
Ref: SREBP1 regulates tumorigenesis and prognosis of pancreatic cancer through targeting lipid metabolism. PMID: 25589463 Ref: Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis. PMID: 25895130 Ref: Up-regulation of fatty acid synthase induced by EGFR/ERK activation promotes tumor growth in pancreatic cancer. PMID: 26043686 |
Ref: Inhibition of Fatty Acid Synthesis Induces Apoptosis of Human Pancreatic Cancer Cells. PMID: 27630308 |
Ref: FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Ex PMID: 28159572 Ref: Sterol regulatory element-binding protein 1 inhibitors decrease pancreatic cancer cell viability and proliferation. PMID: 28483521 Ref: De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer. PMID: 28811332 Ref: Orlistat Reduces Proliferation and Enhances Apoptosis in Human Pancreatic Cancer Cells (PANC-1). PMID: 29061815 |
Ref: Upregulation of pyruvate kinase M2 expression by fatty acid synthase contributes to gemcitabine resistance in pancreatic cancer. PMID: 29434927 |