Literatures

Primary Site >> Colorectal Cancer

Gene >> FASN

1.
Journal:	Hum Pathol. 1997 Jun;28(6):686-92.
Title:	Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival.
Author:	Gansler, T S\|Hardman, W 3rd\|Hunt, D A\|Schaffel, S\|Hennigar, R A
PMID:	9191002

2.
Journal:	Am J Pathol. 1997 Jan;150(1):201-8.
Title:	Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia.
Author:	Rashid, A\|Pizer, E S\|Moga, M\|Milgraum, L Z\|Zahurak, M\|Pasternack, G R\|Kuhajda, F P\|Hamilton, S R
PMID:	9006336

3.
Journal:	Clin Cancer Res. 1999 Dec;5(12):4111-8.
Title:	Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa.
Author:	Visca, P\|Alo, P L\|Del Nonno, F\|Botti, C\|Trombetta, G\|Marandino, F\|Filippi, S\|Di Tondo, U\|Donnorso, R P
PMID:	10632348

4.
Journal:	Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3450-4.
Title:	Synthesis and antitumor activity of an inhibitor of fatty acid synthase.
Author:	Kuhajda, F P\|Pizer, E S\|Li, J N\|Mani, N S\|Frehywot, G L\|Townsend, C A
PMID:	10716717

5.
Journal:	Exp Cell Res. 2000 Nov 25;261(1):159-65.
Title:	Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia.
Author:	Li, J N\|Mahmoud, M A\|Han, W F\|Ripple, M\|Pizer, E S
PMID:	11082286

6.
Journal:	Cancer Res. 2001 Feb 15;61(4):1493-9.
Title:	Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53.
Author:	Li, J N\|Gorospe, M\|Chrest, F J\|Kumaravel, T S\|Evans, M K\|Han, W F\|Pizer, E S
PMID:	11245456

7.
Journal:	Zhonghua Wai Ke Za Zhi. 2004 Jun 7;42(11):672-4.
Title:	[The construction of yeast two-hybrid method in the protein-interactions and its significance in hepatic metastasis of colorectal carcinoma].
Author:	Zuo, Fu-Yi\|Li, Shi-Yong\|An, Ping\|Yu, Bo\|Cai, Hui-Yun
PMID:	15329257

8.
Journal:	Mod Pathol. 2006 Jan;19(1):59-68.
Title:	Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Cantor, Mami\|Namgyal, Chungdak\|Kawasaki, Takako\|Kirkner, Gregory\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Fuchs, Charles S
PMID:	16118624

9.
Journal:	Am J Clin Pathol. 2006 Jul;126(1):113-8.
Title:	Overexpression of fatty acid synthase in ulcerative colitis.
Author:	Consolazio, Adriana\|Alo, Piero Luigi\|Rivera, Margherita\|Iacopini, Federico\|Paoluzi, Omero Alessandro\|Crispino, Pietro\|Pica, Roberta\|Paoluzi, Paolo
PMID:	16753600

10.
Journal:	Oncology. 2006;71(5-6):327-32. Epub 2007 Aug 8.
Title:	Fatty acid synthase hyperactivation in human colorectal cancer: relationship with tumor side and sex.
Author:	Notarnicola, Maria\|Altomare, Donato Francesco\|Calvani, Menotti\|Orlando, Antonella\|Bifulco, Maurizio\|D'Attoma, Benedetta\|Caruso, Maria Gabriella
PMID:	17687193

11.
Journal:	Cancer Biol Ther. 2007 Oct;6(10):1606-13. Epub 2007 Jul 13.
Title:	Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?
Author:	Mazzarelli, Paola\|Pucci, Sabina\|Bonanno, Elena\|Sesti, Fabiola\|Calvani, Menotti\|Spagnoli, Luigi Giusto
PMID:	18253084

12.
Journal:	Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title:	Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17350669

13.
Journal:	Cancer Res. 2007 Feb 1;67(3):1262-9.
Title:	Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
Author:	Little, Joy L\|Wheeler, Frances B\|Fels, Diane R\|Koumenis, Constantinos\|Kridel, Steven J
PMID:	17283163

14.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G868-76.
Title:	Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase.
Author:	Xiao, Rijin\|Su, Ying\|Simmen, Rosalia C M\|Simmen, Frank A
PMID:	18239060

15.
Journal:	Neoplasia. 2008 Jun;10(6):534-41.
Title:	PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author:	Nosho, Katsuhiko\|Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Zepf, Dimity\|Yan, Liying\|Longtine, Janina A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18516290

16.
Journal:	Clin Cancer Res. 2008 Sep 15;14(18):5735-42.
Title:	Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.
Author:	Zhan, Yanai\|Ginanni, Nicole\|Tota, Michael R\|Wu, Margaret\|Bays, Nathan W\|Richon, Victoria M\|Kohl, Nancy E\|Bachman, Eric S\|Strack, Peter R\|Krauss, Stefan
PMID:	18794082

17.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5713-20.
Title:	Cohort study of fatty acid synthase expression and patient survival in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Meyerhardt, Jeffrey A\|Kirkner, Gregory J\|Chan, Andrew T\|Kawasaki, Takako\|Giovannucci, Edward L\|Loda, Massimo\|Fuchs, Charles S
PMID:	18955444

18.
Journal:	Int J Cancer. 2009 Jul 1;125(1):249-52.
Title:	Increased expression of fatty acid synthase in human aberrant crypt foci: possible target for colorectal cancer prevention.
Author:	Kearney, Kathleen E\|Pretlow, Thomas G\|Pretlow, Theresa P
PMID:	19358283

19.
Journal:	Clin Cancer Res. 2009 Sep 15;15(18):5931-6.
Title:	Interaction of molecular markers and physical activity on mortality in patients with colon cancer.
Author:	Meyerhardt, Jeffrey A\|Ogino, Shuji\|Kirkner, Gregory J\|Chan, Andrew T\|Wolpin, Brian\|Ng, Kimmie\|Nosho, Katsuhiko\|Shima, Kaori\|Giovannucci, Edward L\|Loda, Massimo\|Fuchs, Charles S
PMID:	19723652

20.
Journal:	Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title:	A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author:	Nosho, Katsuhiko\|Kure, Shoko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Spiegelman, Donna\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19686742

21.
Journal:	Am J Gastroenterol. 2009 Aug;104(8):2047-56.
Title:	A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Kure, Shoko\|Shima, Kaori\|Irahara, Natsumi\|Toyoda, Saori\|Chen, Li\|Kirkner, Gregory J\|Wolpin, Brian M\|Chan, Andrew T\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19513025

22.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title:	A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author:	Ogino, Shuji\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Wolpin, Brian M\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19505918

23.
Journal:	Am J Gastroenterol. 2009 Jul;104(7):1790-801.
Title:	High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.
Author:	Uddin, Shahab\|Hussain, Azhar R\|Ahmed, Maqbool\|Abubaker, Jehad\|Al-Sanea, Nasser\|Abduljabbar, Alaa\|Ashari, Luai H\|Alhomoud, Samar\|Al-Dayel, Fouad\|Bavi, Prashant\|Al-Kuraya, Khawla S
PMID:	19491830

24.
Journal:	Mod Pathol. 2009 Jul;22(7):922-32.
Title:	SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Firestein, Ron\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19430421

25.
Journal:	Neoplasia. 2009 May;11(5):418-25.
Title:	Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Toyoda, Saori\|Kirkner, Gregory J\|Goel, Ajay\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19412426

26.
Journal:	Gastroenterology. 2009 Apr;136(4):1242-50.
Title:	Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.
Author:	Ogino, Shuji\|Shima, Kaori\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Chen, Li\|Toyoda, Saori\|Kirkner, Gregory J\|Wang, Y Lynn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19186181

27.
Journal:	Int J Cancer. 2009 Jun 1;124(11):2750-3.
Title:	Fatty acid synthase is over-expressed in large aberrant crypt foci in rats treated with azoxymethane.
Author:	Lau, Dominic S Y\|Archer, Michael C
PMID:	19173288

28.
Journal:	Int J Cancer. 2010 Jun 15;126(12):2863-73.
Title:	CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.
Author:	Firestein, Ron\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Bojarski, Emeric\|Giovannucci, Edward L\|Hahn, William C\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19790197

29.
Journal:	Endocr Relat Cancer. 2010 Jun 1;17(2):351-60.
Title:	Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.
Author:	Algire, Carolyn\|Amrein, Lilian\|Zakikhani, Mahvash\|Panasci, Lawrence\|Pollak, Michael
PMID:	20228137

30.
Journal:	Cancer Sci. 2010 Aug;101(8):1861-5.
Title:	Fatty acid synthase inhibitor cerulenin suppresses liver metastasis of colon cancer in mice.
Author:	Murata, Soichiro\|Yanagisawa, Kazuhiko\|Fukunaga, Kiyoshi\|Oda, Tatsuya\|Kobayashi, Akihiko\|Sasaki, Ryoko\|Ohkohchi, Nobuhiro
PMID:	20491775

31.
Journal:	Mol Cancer. 2010 May 27;9:125.
Title:	Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Author:	Baba, Yoshifumi\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Tanaka, Noriko\|Shima, Kaori\|Hazra, Aditi\|Schernhammer, Eva S\|Hunter, David J\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20507599

32.
Journal:	Cancer Res. 2010 Jul 1;70(13):5507-17.
Title:	The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.
Author:	Al-Saffar, Nada M S\|Jackson, L Elizabeth\|Raynaud, Florence I\|Clarke, Paul A\|Ramirez de Molina, Ana\|Lacal, Juan C\|Workman, Paul\|Leach, Martin O
PMID:	20551061

33.
Journal:	Biochimie. 2010 Dec;92(12):1772-7.
Title:	Down-regulation of the phosphoenolpyruvate carboxykinase gene in human colon tumors and induction by omega-3 fatty acids.
Author:	Blouin, Jean-Marc\|Bortoli, Sylvie\|Nacfer, Magali\|Collinet, Martine\|Penot, Graziella\|Laurent-Puig, Pierre\|Forest, Claude
PMID:	20691246

34.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1025-33.
Title:	Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.
Author:	Baba, Y\|Nosho, K\|Shima, K\|Meyerhardt, J A\|Chan, A T\|Engelman, J A\|Cantley, L C\|Loda, M\|Giovannucci, E\|Fuchs, C S\|Ogino, S
PMID:	20808308

35.
Journal:	J Cancer Ther. 2010 Sep;1(3):105-113.
Title:	GREEN TEA POLYPHENOLS MEDIATED APOPTOSIS IN INTESTINAL EPITHELIAL CELLS BY A FADD-DEPENDENT PATHWAY.
Author:	Oz, Helieh S\|Ebersole, Jeffrey L
PMID:	21687829

36.
Journal:	Cancer Microenviron. 2011 Aug;4(2):181-5.
Title:	The colorectal tumor microenvironment: the next decade.
Author:	Beauchemin, Nicole
PMID:	21735168

37.
Journal:	Biomed Pharmacother. 2011 Jul;65(4):286-92.
Title:	Antitumor effect of orlistat, a fatty acid synthase inhibitor, is via activation of caspase-3 on human colorectal carcinoma-bearing animal.
Author:	Chuang, Hui-Yen\|Chang, Ya-Fang\|Hwang, Jeng-Jong
PMID:	21723078

38.
Journal:	Cancer. 2011 Apr 1;117(7):1399-408.
Title:	Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Hayashi, Marika\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21425139

39.
Journal:	Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title:	Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author:	Shima, Kaori\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Cantor, Mami\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20473920

40.
Journal:	Genes Nutr. 2011 Feb;6(1):63-9.
Title:	Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells.
Author:	Notarnicola, Maria\|Pisanti, Simona\|Tutino, Valeria\|Bocale, Domenica\|Rotelli, Maria Teresa\|Gentile, Antonio\|Memeo, Vincenzo\|Bifulco, Maurizio\|Perri, Enzo\|Caruso, Maria Gabriella
PMID:	21437031

41.
Journal:	Anticancer Res. 2012 Jul;32(7):2585-90.
Title:	A significant role of lipogenic enzymes in colorectal cancer.
Author:	Notarnicola, Maria\|Messa, Caterina\|Caruso, Maria Gabriella
PMID:	22753716

42.
Journal:	Clin Cancer Res. 2012 Nov 15;18(22):6136-46.
Title:	Expression profiling of archival tumors for long-term health studies.
Author:	Waldron, Levi\|Ogino, Shuji\|Hoshida, Yujin\|Shima, Kaori\|McCart Reed, Amy E\|Simpson, Peter T\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Segata, Nicola\|Vargas, Ana Cristina\|Cummings, Margaret C\|Lakhani, Sunil R\|Kirkner, Gregory J\|Giovannucci, Edward\|Quackenbush, John\|
PMID:	23136189

43.
Journal:	PLoS One. 2012;7(10):e46716.
Title:	Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Author:	Al-Dwairi, Ahmed\|Pabona, John Mark P\|Simmen, Rosalia C M\|Simmen, Frank A
PMID:	23056418

44.
Journal:	Nutr Cancer. 2012 Aug;64(6):864-70.
Title:	Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway.
Author:	Li, Nan\|Bu, Xiaodong\|Tian, Xiaoqiang\|Wu, Peng\|Yang, Lin\|Huang, Peilin
PMID:	22860766

45.
Journal:	PLoS One. 2012;7(3):e33823.
Title:	SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids.
Author:	Mason, Paul\|Liang, Beirong\|Li, Lingyun\|Fremgen, Trisha\|Murphy, Erin\|Quinn, Angela\|Madden, Stephen L\|Biemann, Hans-Peter\|Wang, Bing\|Cohen, Aharon\|Komarnitsky, Svetlana\|Jancsics, Kate\|Hirth, Brad\|Cooper, Christopher G F\|Lee, Edward\|Wilson, Sean\|Krumbholz, R
PMID:	22457791

46.
Journal:	J Natl Cancer Inst. 2012 Mar 7;104(5):415-20.
Title:	Body mass index and risk of colorectal cancer according to fatty acid synthase expression in the nurses' health study.
Author:	Kuchiba, Aya\|Morikawa, Teppei\|Yamauchi, Mai\|Imamura, Yu\|Liao, Xiaoyun\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22312135

47.
Journal:	Cancer Res. 2012 Mar 15;72(6):1504-17.
Title:	Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
Author:	Zaytseva, Yekaterina Y\|Rychahou, Piotr G\|Gulhati, Pat\|Elliott, Victoria A\|Mustain, William C\|O'Connor, Kathleen\|Morris, Andrew J\|Sunkara, Manjula\|Weiss, Heidi L\|Lee, Eun Y\|Evers, B Mark
PMID:	22266115

48.
Journal:	Lipids. 2012 Apr;47(4):403-11.
Title:	The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.
Author:	Li, Nan\|Bu, Xiaodong\|Wu, Peng\|Wu, Pingping\|Huang, Peilin
PMID:	22218925

49.
Journal:	Lipids. 2012 Jan;47(1):59-63.
Title:	Low levels of lipogenic enzymes in peritumoral adipose tissue of colorectal cancer patients.
Author:	Notarnicola, Maria\|Miccolis, Angelica\|Tutino, Valeria\|Lorusso, Dionigi\|Caruso, Maria Gabriella
PMID:	22090062

50.
Journal:	J Gastrointest Cancer. 2012 Sep;43(3):508-11.
Title:	Serum levels of fatty acid synthase in colorectal cancer patients are associated with tumor stage.
Author:	Notarnicola, Maria\|Tutino, Valeria\|Calvani, Menotti\|Lorusso, Dionigi\|Guerra, Vito\|Caruso, Maria Gabriella
PMID:	21727995

51.
Journal:	J Gastroenterol. 2013 Feb;48(2):182-92.
Title:	The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells.
Author:	Kwan, Hiu-Yee\|Yang, Zhijun\|Fong, Wang-Fun\|Hu, Yong-Mei\|Yu, Zhi-Ling\|Hsiao, Wen-Luan Wendy
PMID:	22722903

52.
Journal:	Lipids Health Dis. 2013 Jun 1;12:83.
Title:	Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.
Author:	Li, Nan\|Lu, Heng\|Chen, Chunyan\|Bu, Xiaodong\|Huang, Peilin
PMID:	23725225

53.
Journal:	Int J Oncol. 2013 Aug;43(2):431-8.
Title:	Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells.
Author:	Shiragami, Risa\|Murata, Soichiro\|Kosugi, Chihiro\|Tezuka, Tohru\|Yamazaki, Masato\|Hirano, Atsushi\|Yoshimura, Yukino\|Suzuki, Masato\|Shuto, Kiyohiko\|Koda, Keiji
PMID:	23754252

54.
Journal:	Med Oncol. 2014 Oct;31(10):192.
Title:	Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians.
Author:	Keshk, Walaa Arafa\|Zineldeen, Doaa Hussein\|Wasfy, Rania E L-sayed\|El-Khadrawy, Osama Helmy
PMID:	25173531

55.
Journal:	Cancer Epidemiol Biomarkers Prev. 2014 Nov;23(11):2413-21.
Title:	Colonic mucosal fatty acid synthase as an early biomarker for colorectal neoplasia: modulation by obesity and gender.
Author:	Cruz, Mart Dela\|Wali, Ramesh K\|Bianchi, Laura K\|Radosevich, Andrew J\|Crawford, Susan E\|Jepeal, Lisa\|Goldberg, Michael J\|Weinstein, Jaclyn\|Momi, Navneet\|Roy, Priya\|Calderwood, Audrey H\|Backman, Vadim\|Roy, Hemant K
PMID:	25155760

56.
Journal:	Carcinogenesis. 2014 Jun;35(6):1341-51.
Title:	Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.
Author:	Zaytseva, Yekaterina Y\|Elliott, Victoria A\|Rychahou, Piotr\|Mustain, W Conan\|Kim, Ji Tae\|Valentino, Joseph\|Gao, Tianyan\|O'Connor, Kathleen L\|Neltner, Janna M\|Lee, Eun Y\|Weiss, Heidi L\|Evers, B Mark
PMID:	24510238

57.
Journal:	Tumour Biol. 2014 Apr;35(4):3855-9.
Title:	Fatty acid synthase (FASN) levels in serum of colorectal cancer patients: correlation with clinical outcomes.
Author:	Long, Qi-qiang\|Yi, Yong-xiang\|Qiu, Jie\|Xu, Chuan-jun\|Huang, Pei-lin
PMID:	24430360

58.
Journal:	PLoS One. 2014 Jun 11;9(6):e99254.
Title:	Alpha-2-glycoprotein 1(AZGP1) regulates biological behaviors of LoVo cells by down-regulating mTOR signaling pathway and endogenous fatty acid synthesis.
Author:	Chang, Ligong\|Tian, Xiaoqiang\|Lu, Yinghui\|Jia, Min\|Wu, Peng\|Huang, Peilin
PMID:	24918753

59.
Journal:	J Proteomics. 2015 Jan 15;113:326-36.
Title:	Identification of anti-metastatic drug and natural compound targets in isogenic colorectal cancer cells.
Author:	Lee, Jin-Gyun\|McKinney, Kimberly Q\|Pavlopoulos, Antonis J\|Park, Jeong-Hill\|Hwang, Sunil
PMID:	25451013

60.
Journal:	J Steroid Biochem Mol Biol. 2015 Apr;148:172-8.
Title:	Remodeling of phospholipid composition in colon cancer cells by 1alpha,25(OH)2D3 and its analogs.
Author:	Leyssens, Carlien\|Marien, Eyra\|Verlinden, Lieve\|Derua, Rita\|Waelkens, Etienne\|Swinnen, Johannes V\|Verstuyf, Annemieke
PMID:	25625664

61.
Journal:	Oncotarget. 2015 Aug 7;6(22):18891-904.
Title:	Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration.
Author:	Zaytseva, Yekaterina Y\|Harris, Jennifer W\|Mitov, Mihail I\|Kim, Ji Tae\|Butterfield, D Allan\|Lee, Eun Y\|Weiss, Heidi L\|Gao, Tianyan\|Evers, B Mark
PMID:	25970773

62.
Journal:	Int J Oncol. 2015 Aug;47(2):764-72.
Title:	Influence of fatty acid synthase inhibitor orlistat on the DNA repair enzyme O6-methylguanine-DNA methyltransferase in human normal or malignant cells in vitro.
Author:	Cioccoloni, Giorgia\|Bonmassar, Laura\|Pagani, Elena\|Caporali, Simona\|Fuggetta, Maria Pia\|Bonmassar, Enzo\|D'Atri, Stefania\|Aquino, Angelo
PMID:	26035182

63.
Journal:	Oncol Res Treat. 2015;38(10):511-6.
Title:	L-Carnitine Ameliorates Cancer Cachexia in Mice Partly via the Carnitine Palmitoyltransferase-Associated PPAR-gamma Signaling Pathway.
Author:	Jiang, Fang\|Zhang, Zongqi\|Zhang, Yi\|Pan, Xiaohui\|Yu, Li\|Liu, Su
PMID:	26452216

64.
Journal:	Genes Nutr. 2015 Nov;10(6):49.
Title:	Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells.
Author:	Montales, Maria Theresa E\|Simmen, Rosalia C M\|Ferreira, Ederlan S\|Neves, Valdir A\|Simmen, Frank A
PMID:	26506839

65.
Journal:	Oncotarget. 2015 Nov 10;6(35):38166-80.
Title:	Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Author:	Greening, David W\|Lee, Sze Ting\|Ji, Hong\|Simpson, Richard J\|Rigopoulos, Angela\|Murone, Carmel\|Fang, Catherine\|Gong, Sylvia\|O'Keefe, Graeme\|Scott, Andrew M
PMID:	26517691

66.
Journal:	Cancer Med. 2016 Jul;5(7):1599-606.
Title:	Fatty acid synthase regulates invasion and metastasis of colorectal cancer via Wnt signaling pathway.
Author:	Wang, Haiyu\|Xi, Qiulei\|Wu, Guohao
PMID:	27139420

67.
Journal:	J Cancer Res Clin Oncol. 2016 Jan;142(1):59-72.
Title:	Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.
Author:	Chang, Ligong\|Wu, Peng\|Senthilkumar, Ravichandran\|Tian, Xiaoqiang\|Liu, Hui\|Shen, Xia\|Tao, Zijian\|Huang, Peilin
PMID:	26109148

68.
Journal:	Mol Med Rep. 2017 Apr;15(4):2163-2173.
Title:	Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
Author:	Lee, Kyung Ha\|Lee, Myung Sun\|Cha, Eun Young\|Sul, Ji Young\|Lee, Jin Sun\|Kim, Jin Su\|Park, Jun Beom\|Kim, Ji Yeon
PMID:	28260110

69.
Journal:	Int J Cancer. 2017 Jun 15;140(12):2648-2656.
Title:	Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers.
Author:	Keum, NaNa\|Yuan, Chen\|Nishihara, Reiko\|Zoltick, Emilie\|Hamada, Tsuyoshi\|Martinez Fernandez, Alejandro\|Zhang, Xuehong\|Hanyuda, Akiko\|Liu, Li\|Kosumi, Keisuke\|Nowak, Jonathan A\|Jhun, Iny\|Soong, T Rinda\|Morikawa, Teppei\|Tabung, Fred K\|Qian, Zhi Rong\|Fuchs, Ch
PMID:	28268248

70.
Journal:	Oncol Rep. 2017 May;37(5):2583-2592.
Title:	MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression.
Author:	Duan, Jiangman\|Chen, Lishan\|Zhou, Minyu\|Zhang, Jingwen\|Sun, Li\|Huang, Na\|Bin, Jianping\|Liao, Yulin\|Liao, Wangjun
PMID:	28339092

71.
Journal:	Eur J Epidemiol. 2017 May;32(5):393-407.
Title:	Body mass index and risk of colorectal carcinoma subtypes classified by tumor differentiation status.
Author:	Hanyuda, Akiko\|Cao, Yin\|Hamada, Tsuyoshi\|Nowak, Jonathan A\|Qian, Zhi Rong\|Masugi, Yohei\|da Silva, Annacarolina\|Liu, Li\|Kosumi, Keisuke\|Soong, Thing Rinda\|Jhun, Iny\|Wu, Kana\|Zhang, Xuehong\|Song, Mingyang\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles
PMID:	28510098

72.
Journal:	Oncol Rep. 2017 Dec;38(6):3497-3506.
Title:	Expression of fatty acid synthase is regulated by PGC1alpha and contributes to increased cell proliferation.
Author:	Yun, Seong-Hoon\|Shin, Sung-Won\|Park, Joo-In
PMID:	29130104

73.
Journal:	J Gastrointest Cancer. 2018 Apr 21. pii: 10.1007/s12029-018-0104-5.
Title:	Immunohistochemical Expression of Fatty Acid Synthase and Vascular Endothelial Growth Factor in Primary Colorectal Cancer: a Clinicopathological Study.
Author:	Mohamed, Asmaa Hussein\|Said, Nelly Mohamed
PMID:	29681001

74.
Journal:	Neoplasia. 2018 Jul;20(7):668-677.
Title:	Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab.
Author:	Taniguchi, Hiroya\|Baba, Yuji\|Sagiya, Yoji\|Gotou, Masamitsu\|Nakamura, Kazuhide\|Sawada, Hiroshi\|Yamanaka, Kazunori\|Sakakibara, Yukiko\|Mori, Ikuo\|Hikichi, Yukiko\|Soeda, Junpei\|Baba, Hideo
PMID:	29802988

75.
Journal:	Oncotarget. 2018 May 15;9(37):24787-24800.
Title:	Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.
Author:	Zaytseva, Yekaterina Y\|Rychahou, Piotr G\|Le, Anh-Thu\|Scott, Timothy L\|Flight, Robert M\|Kim, Ji Tae\|Harris, Jennifer\|Liu, Jinpeng\|Wang, Chi\|Morris, Andrew J\|Sivakumaran, Theru A\|Fan, Teresa\|Moseley, Hunter\|Gao, Tianyan\|Lee, Eun Y\|Weiss, Heidi L\|Heuer, Timo
PMID:	29872506

76.
Journal:	Mol Cancer Res. 2018 Aug 28. pii: 1541-7786.MCR-18-0199.
Title:	De Novo Fatty Acid Synthesis Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer.
Author:	Jafari, Naser\|Drury, James\|Morris, Andrew J\|Onono, Fredrick O\|Stevens, Payton D\|Gao, Tianyan\|Liu, Jinpeng\|Wang, Chi\|Lee, Eun Y\|Weiss, Heidi L\|Evers, B Mark\|Zaytseva, Yekaterina Y
PMID:	30154249

77.
Journal:	J Recept Signal Transduct Res. 2018 Sep 26:1-7.
Title:	In silico screening for identification of fatty acid synthase inhibitors and evaluation of their antiproliferative activity using human cancer cell lines.
Author:	Nisthul A, Amrutha\|Retnakumari, Archana P\|A, Shabna\|Anto, Ruby John\|Sadasivan, C
PMID:	30256698