Primary Site >> Colorectal Cancer

Gene >> FADD

Journal: Cell Death Differ. 1998 Jun;5(6):480-7.
Title: Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate.
Author: Bonnotte, B|Favre, N|Reveneau, S|Micheau, O|Droin, N|Garrido, C|Fontana, A|Chauffert, B|Solary, E|Martin, F
PMID: 10200499
Journal: Cell Death Differ. 1998 May;5(5):450-7.
Title: Expression of genes that regulate Fas signalling and Fas-mediated apoptosis in colon carcinoma cells.
Author: Tillman, D M|Harwood, F G|Gibson, A A|Houghton, J A
PMID: 10200495
Journal: J Biol Chem. 1999 Mar 19;274(12):7987-92.
Title: Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.
Author: Micheau, O|Solary, E|Hammann, A|Dimanche-Boitrel, M T
PMID: 10075697
Journal: Biochem Biophys Res Commun. 1999 Mar 24;256(3):603-7.
Title: STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.
Author: Micheau, O|Hammann, A|Solary, E|Dimanche-Boitrel, M T
PMID: 10080945
Journal: Biol Pharm Bull. 2000 Apr;23(4):420-6.
Title: Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis.
Author: Han, S Y|Choung, S Y|Paik, I S|Kang, H J|Choi, Y H|Kim, S J|Lee, M O
PMID: 10784420
Journal: Cancer Res. 2000 Nov 15;60(22):6259-65.
Title: The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Author: Ozoren, N|Kim, K|Burns, T F|Dicker, D T|Moscioni, A D|El-Deiry, W S
PMID: 11103780
Journal: Nat Med. 2001 Jan;7(1):88-93.
Title: SADS: A new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma.
Author: Suzuki, A|Obata, S|Hayashida, M|Kawano, H|Nakano, T|Shiraki, K
PMID: 11135621
Journal: Oncogene. 2001 Apr 5;20(15):1852-9.
Title: Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.
Author: Shao, R G|Cao, C X|Nieves-Neira, W|Dimanche-Boitrel, M T|Solary, E|Pommier, Y
PMID: 11313933
Journal: Cancer Res. 2001 Jun 1;61(11):4445-9.
Title: Selective targeting to the hyperactive beta-catenin/T-cell factor pathway in colon cancer cells.
Author: Chen, R H|McCormick, F
PMID: 11389074
Journal: J Biol Chem. 2001 Oct 19;276(42):38748-54. Epub 2001 Aug 20.
Title: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line.
Author: Han, Z|Pantazis, P|Wyche, J H|Kouttab, N|Kidd, V J|Hendrickson, E A
PMID: 11514566
Journal: Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title: Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author: Ozoren, Nesrin|El-Deiry, Wafik S
PMID: 12407450
Journal: J Biol Chem. 2003 Oct 17;278(42):41482-90. Epub 2003 Aug 5.
Title: Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells.
Author: Delmas, Dominique|Rebe, Cedric|Lacour, Sandrine|Filomenko, Rodolphe|Athias, Anne|Gambert, Philippe|Cherkaoui-Malki, Mustapha|Jannin, Brigitte|Dubrez-Daloz, Laurence|Latruffe, Norbert|Solary, Eric
PMID: 12902349
Journal: Oncogene. 2003 Aug 7;22(32):4953-63.
Title: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author: Johnson, Thomas R|Stone, Kimberley|Nikrad, Malti|Yeh, Tammie|Zong, Wei-Xing|Thompson, Craig B|Nesterov, Alexandre|Kraft, Andrew S
PMID: 12902978
Journal: Clin Cancer Res. 2003 Dec 15;9(17):6504-15.
Title: Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.
Author: Geller, James|Petak, Istvan|Szucs, Kinga Szekely|Nagy, Katalin|Tillman, David M|Houghton, Janet A
PMID: 14695155
Journal: Oncol Res. 2004;14(9):427-38.
Title: Modulation of Wnt-specific colon cancer cell kill by butyrate and lithium.
Author: Bordonaro, Michael|Lazarova, Darina L|Carbone, Rocco|Sartorelli, Alan C
PMID: 15490974
Journal: APMIS. 2004 Sep;112(9):595-7.
Title: Mutation of FADD gene is rare in human colon and stomach cancers.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Nam, Suk Woo|Park, Won Sang|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 15601308
Journal: Cancer Res. 2005 Dec 15;65(24):11447-58.
Title: Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae.
Author: Martin, Sophie|Phillips, Darren C|Szekely-Szucs, Kinga|Elghazi, Lynda|Desmots, Fabienne|Houghton, Janet A
PMID: 16357153
Journal: Adv Med Sci. 2006;51:39-45.
Title: Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis.
Author: Pajak, B|Orzechowski, A
PMID: 17357275
Journal: Phytomedicine. 2007 Apr;14(4):263-72.
Title: Antiproliferative activity and induction of apoptosis in human colon cancer cells treated in vitro with constituents of a product derived from Pistacia lentiscus L. var. chia.
Author: Balan, K V|Prince, J|Han, Z|Dimas, K|Cladaras, M|Wyche, J H|Sitaras, N M|Pantazis, P
PMID: 16713222
Journal: Apoptosis. 2007 Jul;12(7):1299-315.
Title: Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells.
Author: Garnett, Theodore O|Filippova, Maria|Duerksen-Hughes, Penelope Jayne
PMID: 17431792
Journal: Med Oncol. 2010 Jun;27(2):397-405.
Title: Overexpression of FADD enhances 5-fluorouracil-induced apoptosis in colorectal adenocarcinoma cells.
Author: Yin, Anning|Jiang, Yingan|Zhang, Xianfeng|Luo, Hesheng
PMID: 19415536
Journal: Apoptosis. 2010 May;15(5):597-607.
Title: The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells.
Author: Conrad, David M|Furlong, Suzanne J|Doucette, Carolyn D|West, Kenneth A|Hoskin, David W
PMID: 20094800
Journal: Eur J Cancer. 2010 May;46(8):1445-55.
Title: Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.
Author: Rebillard, Amelie|Jouan-Lanhouet, Sandrine|Jouan, Elodie|Legembre, Patrick|Pizon, Mathieu|Sergent, Odile|Gilot, David|Tekpli, Xavier|Lagadic-Gossmann, Dominique|Dimanche-Boitrel, Marie-Therese
PMID: 20202822
Journal: Toxicol In Vitro. 2010 Sep;24(6):1546-53.
Title: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells.
Author: Go, Hiroe|Hwang, Hye-Jung|Nam, Taek-Jeong
PMID: 20615460
Journal: J Cancer Ther. 2010 Sep;1(3):105-113.
Title: GREEN TEA POLYPHENOLS MEDIATED APOPTOSIS IN INTESTINAL EPITHELIAL CELLS BY A FADD-DEPENDENT PATHWAY.
Author: Oz, Helieh S|Ebersole, Jeffrey L
PMID: 21687829
Journal: Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A
PMID: 21135115
Journal: Oncol Lett. 2011 Jan;2(1):43-47.
Title: Apigenin suppresses the growth of colorectal cancer xenografts via phosphorylation and up-regulated FADD expression.
Author: Wang, Qi Rui|Yao, Xue Qing|Wen, Ge|Fan, Qin|Li, Ying-Jia|Fu, Xiu Qiong|Li, Chang Ke|Sun, Xue Gang
PMID: 22870126
Journal: J Biol Chem. 2011 Dec 16;286(50):43123-33.
Title: GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation.
Author: Moriwaki, Kenta|Shinzaki, Shinichiro|Miyoshi, Eiji
PMID: 22027835
Journal: Oncogene. 2011 Jul 28;30(30):3345-59.
Title: IL-32gamma inhibits cancer cell growth through inactivation of NF-kappaB and STAT3 signals.
Author: Oh, J H|Cho, M-C|Kim, J-H|Lee, S Y|Kim, H J|Park, E S|Ban, J O|Kang, J-W|Lee, D-H|Shim, J-H|Han, S B|Moon, D C|Park, Y H|Yu, D-Y|Kim, J-M|Kim, S H|Yoon, D-Y|Hong, J T
PMID: 21423208
Journal: Oncol Rep. 2011 Feb;25(2):419-24.
Title: Death receptor 5-mediated TNFR family signaling pathways modulate gamma-humulene-induced apoptosis in human colorectal cancer HT29 cells.
Author: Lan, Yu-Hsuan|Wu, Yang-Chang|Wu, Kai-Wei|Chung, Jing-Gung|Lu, Chi-Cheng|Chen, Yuan-Liang|Wu, Tian-Shung|Yang, Jai-Sing
PMID: 21152878
Journal: J Biol Chem. 2011 Jul 1;286(26):22982-90.
Title: Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Author: Swindall, Amanda F|Bellis, Susan L
PMID: 21550977
Journal: Apoptosis. 2013 Nov;18(11):1391-402.
Title: Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress.
Author: Cao, Aili|Li, Qi|Yin, Peihao|Dong, Yang|Shi, Hailian|Wang, Li|Ji, Guang|Xie, Jianqun|Wu, Dazheng
PMID: 23881281
Journal: Oncol Lett. 2014 May;7(5):1728-1732.
Title: Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author: Ji, Chen-Feng|Ji, Yu-Bin
PMID: 24765209
Journal: Cancer Biol Ther. 2014;15(12):1646-57.
Title: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author: Booth, Laurence|Cruickshanks, Nichola|Tavallai, Seyedmehrad|Roberts, Jane L|Peery, Matthew|Poklepovic, Andrew|Dent, Paul
PMID: 25482938
Journal: Anticancer Res. 2015 Oct;35(10):5407-16.
Title: Synthetic Bichalcone TSWU-BR23 Induces Apoptosis of Human Colon Cancer HT-29 Cells by p53-Mediated Mitochondrial Oligomerization of BAX/BAK and Lipid Raft Localization of CD95/FADD.
Author: Lin, Meng-Liang|Chen, Shih-Shun|Wu, Tian-Shung
PMID: 26408703
Journal: Biomaterials. 2015 Dec;71:84-99.
Title: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Author: Roy, Kislay|Kanwar, Rupinder K|Kanwar, Jagat R
PMID: 26318819
Journal: World J Gastroenterol. 2015 May 28;21(20):6194-205.
Title: Gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways.
Author: Huang, Guang-Ming|Sun, Yu|Ge, Xin|Wan, Xin|Li, Chun-Bo
PMID: 26034354
Journal: Cell Death Dis. 2015 Apr 23;6:e1729.
Title: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Author: Brown, M F|Leibowitz, B J|Chen, D|He, K|Zou, F|Sobol, R W|Beer-Stolz, D|Zhang, L|Yu, J
PMID: 25906152
Journal: J Hematol Oncol. 2015 Mar 15;8:26.
Title: Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author: Wang, He|Yang, Shu|Zhou, Hong|Sun, Mingna|Du, Lingran|Wei, Minyan|Luo, Meixia|Huang, Jingzhu|Deng, Hongzhu|Feng, Yinghong|Huang, Jun|Zhou, Yi
PMID: 25886453
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Oncogene. 2016 Jan 14;35(2):148-57.
Title: mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
Author: He, K|Zheng, X|Li, M|Zhang, L|Yu, J
PMID: 25867072
Journal: Oncotarget. 2016 Jan 26;7(4):3709-25.
Title: Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells.
Author: Roesler, Stefanie|Eckhardt, Ines|Wolf, Sebastian|Fulda, Simone
PMID: 26788912
Journal: Oncotarget. 2016 Jul 26;7(30):47699-47710.
Title: BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells.
Author: He, Kan|Chen, Dongshi|Ruan, Hang|Li, Xiangyun|Tong, Jingshan|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 27351224
Journal: Sci Rep. 2016 Sep 13;6:32979.
Title: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
Author: Ray, Pallab|Guha, Deblina|Chakraborty, Juni|Banerjee, Shuvomoy|Adhikary, Arghya|Chakraborty, Samik|Das, Tanya|Sa, Gaurisankar
PMID: 27622714
Journal: Chin Clin Oncol. 2016 Dec;5(6):76.
Title: Metallothionein 2A an interactive protein linking phosphorylated FADD to NF-kappaB pathway leads to colorectal cancer formation.
Author: Marikar, Faiz M M T|Jin, Guanghui|Sheng, Wang|Ma, Dingyuan|Hua, Zichun
PMID: 28061540
Journal: Mol Carcinog. 2018 Mar;57(3):347-360.
Title: Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.
Author: Conde-Rioll, Maria|Gajate, Consuelo|Fernandez, Jose J|Villa-Pulgarin, Janny A|Napolitano, Jose G|Norte, Manuel|Mollinedo, Faustino
PMID: 29073716
Journal: Apoptosis. 2018 May 12. pii: 10.1007/s10495-018-1457-8.
Title: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells.
Author: Cheah, Foo Kit|Leong, Kok Hoong|Thomas, Noel Francis|Chin, Hui Kee|Ariffin, Azhar|Awang, Khalijah
PMID: 29754265
Journal: Cell Mol Biol (Noisy-le-grand). 2018 May 15;64(6):31-35.
Title: Adenovirus-mediated overexpression FADD induces a significant antitumor effect on human colorectal cancer cells both in vitro and in vivo.
Author: He, Xueling|Peng, Xu|Liu, Yan|Zhang, Xiaomei|Li, Hualing|Yin, Hailin
PMID: 29808797
Journal: J Cell Physiol. 2018 Sep 10.
Title: Neratinib augments the lethality of [regorafenib + sildenafil].
Author: Booth, Laurence|Roberts, Jane L|Rais, Rumeesa|Cutler, Richard E Jr|Diala, Irmina|Lalani, Alshad S|Hancock, John F|Poklepovic, Andrew|Dent, Paul
PMID: 30203445
Journal: J Cachexia Sarcopenia Muscle. 2018 Oct 3.
Title: Peritumoural adipose tissue pro-inflammatory cytokines are associated with tumoural growth factors in cancer cachexia patients.
Author: Neto, Nelson Inacio Pinto|Murari, Ariene Soares de Pinho|Oyama, Lila Missae|Otoch, Jose Pinhata|Alcantara, Paulo Sergio Martins|Tokeshi, Flavio|Figueredo, Raquel Galvao|Alves, Michele Joana|Lima, Joanna Darck Carola Correia|Matos-Neto, Emidio Marques de|S
PMID: 30284380