Primary Site >> Colorectal Cancer
Gene >> FADD
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Ref: Expression of genes that regulate Fas signalling and Fas-mediated apoptosis in colon carcinoma cells. PMID: 10200495 Ref: Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate. PMID: 10200499 |
Ref: Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. PMID: 10075697 Ref: STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. PMID: 10080945 |
Ref: Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis. PMID: 10784420 Ref: The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand. PMID: 11103780 |
Ref: SADS: A new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma. PMID: 11135621 Ref: Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells. PMID: 11313933 Ref: Selective targeting to the hyperactive beta-catenin/T-cell factor pathway in colon cancer cells. PMID: 11389074 Ref: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line. PMID: 11514566 |
Ref: Defining characteristics of Types I and II apoptotic cells in response to TRAIL. PMID: 12407450 |
Ref: Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. PMID: 12902349 Ref: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. PMID: 12902978 Ref: Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin. PMID: 14695155 |
Ref: Modulation of Wnt-specific colon cancer cell kill by butyrate and lithium. PMID: 15490974 Ref: Mutation of FADD gene is rare in human colon and stomach cancers. PMID: 15601308 |
Ref: Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. PMID: 16357153 |
Ref: Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis. PMID: 17357275 |
Ref: Antiproliferative activity and induction of apoptosis in human colon cancer cells treated in vitro with constituents of a product derived from Pistacia lentiscus L. var. chia. PMID: 16713222 Ref: Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells. PMID: 17431792 |
Ref: Overexpression of FADD enhances 5-fluorouracil-induced apoptosis in colorectal adenocarcinoma cells. PMID: 19415536 Ref: The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells. PMID: 20094800 Ref: Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells. PMID: 20202822 Ref: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells. PMID: 20615460 Ref: GREEN TEA POLYPHENOLS MEDIATED APOPTOSIS IN INTESTINAL EPITHELIAL CELLS BY A FADD-DEPENDENT PATHWAY. PMID: 21687829 |
Ref: Hedgehog signaling drives cellular survival in human colon carcinoma cells. PMID: 21135115 Ref: Death receptor 5-mediated TNFR family signaling pathways modulate gamma-humulene-induced apoptosis in human colorectal cancer HT29 cells. PMID: 21152878 Ref: IL-32gamma inhibits cancer cell growth through inactivation of NF-kappaB and STAT3 signals. PMID: 21423208 Ref: Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells. PMID: 21550977 Ref: GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. PMID: 22027835 Ref: Apigenin suppresses the growth of colorectal cancer xenografts via phosphorylation and up-regulated FADD expression. PMID: 22870126 |
Ref: Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress. PMID: 23881281 |
Ref: Laminarin-induced apoptosis in human colon cancer LoVo cells. PMID: 24765209 Ref: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors. PMID: 25482938 |
Ref: Nexavar/Stivarga and viagra interact to kill tumor cells. PMID: 25704960 Ref: Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms. PMID: 25886453 Ref: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. PMID: 25906152 Ref: Gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways. PMID: 26034354 Ref: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging. PMID: 26318819 Ref: Synthetic Bichalcone TSWU-BR23 Induces Apoptosis of Human Colon Cancer HT-29 Cells by p53-Mediated Mitochondrial Oligomerization of BAX/BAK and Lipid Raft Localization of CD95/FADD. PMID: 26408703 |
Ref: mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation. PMID: 25867072 Ref: Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells. PMID: 26788912 Ref: BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells. PMID: 27351224 Ref: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer. PMID: 27622714 Ref: Metallothionein 2A an interactive protein linking phosphorylated FADD to NF-kappaB pathway leads to colorectal cancer formation. PMID: 28061540 |
Ref: Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component. PMID: 29073716 Ref: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells. PMID: 29754265 Ref: Adenovirus-mediated overexpression FADD induces a significant antitumor effect on human colorectal cancer cells both in vitro and in vivo. PMID: 29808797 Ref: Neratinib augments the lethality of [regorafenib + sildenafil]. PMID: 30203445 Ref: Peritumoural adipose tissue pro-inflammatory cytokines are associated with tumoural growth factors in cancer cachexia patients. PMID: 30284380 |