Primary Site >> Stomach Cancer

Gene >> F2R

Journal: J Biol Chem. 2000 Feb 18;275(7):4592-8.
Title: Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Author: Miyata, S|Koshikawa, N|Yasumitsu, H|Miyazaki, K
PMID: 10671485
Journal: Cancer Sci. 2006 Jan;97(1):64-71.
Title: Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.
Author: Yamashita, Satoshi|Tsujino, Yoshimi|Moriguchi, Kazuki|Tatematsu, Masae|Ushijima, Toshikazu
PMID: 16367923
Journal: Anticancer Res. 2008 Mar-Apr;28(2A):847-54.
Title: Prognostic value of protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1) in gastric cancer.
Author: Fujimoto, Daisuke|Hirono, Yasuo|Goi, Takanori|Katayama, Kanji|Yamaguchi, Akio
PMID: 18507028
Journal: Oncol Rep. 2008 Dec;20(6):1545-51.
Title: Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line.
Author: Tsutani, Yasuhiro|Yoshida, Kazuhiro|Sanada, Yuichi|Wada, Yoshiyuki|Konishi, Kazuo|Fukushima, Masakazu|Okada, Morihito
PMID: 19020740
Journal: Anat Rec (Hoboken). 2009 Feb;292(2):262-70.
Title: Gene expression profiling in TWIST-depleted gastric cancer cells.
Author: Feng, Mei-Yan|Wang, Kuan|Shi, Qing-Tao|Yu, Xiu-Wen|Geng, Jing-Shu
PMID: 19051271
Journal: Ann Oncol. 2010 Jan;21(1):78-86.
Title: Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma.
Author: Lurje, G|Husain, H|Power, D G|Yang, D|Groshen, S|Pohl, A|Zhang, W|Ning, Y|Manegold, P C|El-Khoueiry, A|Iqbal, S|Tang, L H|Shah, M A|Lenz, H-J
PMID: 19622587
Journal: BMC Cancer. 2010 Aug 19;10:443.
Title: The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion.
Author: Fujimoto, Daisuke|Hirono, Yasuo|Goi, Takanori|Katayama, Kanji|Matsukawa, Shigeru|Yamaguchi, Akio
PMID: 20723226
Journal: PLoS One. 2011;6(9):e25103.
Title: Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1).
Author: Kim, Seok-Jun|Shin, Ji-Young|Lee, Kang-Duck|Bae, Young-Ki|Choi, Il-Ju|Park, Seok Hee|Chun, Kyung-Hee
PMID: 21966428
Journal: Int J Oncol. 2013 Feb;42(2):565-73.
Title: The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion.
Author: Fujimoto, Daisuke|Hirono, Yasuo|Goi, Takanori|Katayama, Kanji|Matsukawa, Shigeru|Yamaguchi, Akio
PMID: 23242308
Journal: Gastric Cancer. 2013 Jul;16(3):345-54.
Title: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells.
Author: Mori, Ryutaro|Yoshida, Kazuhiro|Tanahashi, Toshiyuki|Yawata, Kazunori|Kato, Junko|Okumura, Naoki|Tsutani, Yasuhiro|Okada, Morihito|Oue, Naohide|Yasui, Wataru
PMID: 22968820
Journal: Tumour Biol. 2014 Aug;35(8):7821-9.
Title: ncRuPAR inhibits gastric cancer progression by down-regulating protease-activated receptor-1.
Author: Liu, Long|Yan, Bing|Yang, Zhihui|Zhang, Xiaodong|Gu, Qunhao|Yue, Xiaoqiang
PMID: 24817013
Journal: Int J Oncol. 2014 Dec;45(6):2287-94.
Title: Thrombin conducts epithelialmesenchymal transition via proteaseactivated receptor1 in human gastric cancer.
Author: Otsuki, Tadayoshi|Fujimoto, Daisuke|Hirono, Yasuo|Goi, Takanori|Yamaguchi, Akio
PMID: 25231630
Journal: Cancer Res Treat. 2015 Oct;47(4):718-26.
Title: Overexpression of Plasminogen Activator Inhibitor-1 in Advanced Gastric Cancer with Aggressive Lymph Node Metastasis.
Author: Suh, Yun-Suhk|Yu, Jieun|Kim, Byung Chul|Choi, Boram|Han, Tae-Su|Ahn, Hye Seong|Kong, Seong-Ho|Lee, Hyuk-Joon|Kim, Woo Ho|Yang, Han-Kwang
PMID: 25687870
Journal: Med Oncol. 2015 May;32(5):162.
Title: Endothelial cell protein C receptor promotes MGC803 gastric cancer cells proliferation and migration by activating ERK1/2.
Author: Wang, Qingling|Liu, Qingru|Wang, Tianyuan|Yang, Hongli|Han, Zhengjie|Zhang, Peng
PMID: 25895599
Journal: Oncotarget. 2015 Oct 27;6(33):34788-99.
Title: PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway.
Author: Fujimoto, Daisuke|Ueda, Yuki|Hirono, Yasuo|Goi, Takanori|Yamaguchi, Akio
PMID: 26431277
Journal: Biomed Rep. 2016 Apr;4(4):489-492.
Title: Clinical significance of serum protease-activated receptor-1 levels in gastric cancer patients.
Author: Tas, Faruk|Karabulut, Senem|Tastekin, Didem|Duranyildiz, Derya
PMID: 27073639
Journal: Oncol Rep. 2018 Apr;39(4):1843-1852.
Title: Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner.
Author: Wang, Qingling|Yang, Hongli|Zhuo, Qian|Xu, Yanyan|Zhang, Peng
PMID: 29484413
Journal: Oncol Lett. 2018 Aug;16(2):1565-1570.
Title: EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis in vitro through activating ERK1/2 and AKT in a PAR1-dependent manner.
Author: Wang, Qingling|Tang, Yangyang|Wang, Tianyuan|Yang, Hong-Li|Wang, Xinyue|Ma, Hongru|Zhang, Peng
PMID: 30008838
Journal: Gastric Cancer. 2018 Oct 1. pii: 10.1007/s10120-018-0881-3.
Title: The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells.
Author: Mori, Ryutaro|Yoshida, Kazuhiro|Futamura, Manabu|Suetsugu, Tomonari|Shizu, Kaoru|Tanahashi, Toshiyuki|Tanaka, Yoshihiro|Matsuhashi, Nobuhisha|Yamaguchi, Kazuya
PMID: 30276573