Primary Site >> Stomach Cancer

Gene >> F2R

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Ref: Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
PMID: 10671485
Ref: Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.
PMID: 16367923
Ref: Prognostic value of protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1) in gastric cancer.
PMID: 18507028
Ref: Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line.
PMID: 19020740
Ref: Gene expression profiling in TWIST-depleted gastric cancer cells.
PMID: 19051271
Ref: Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma.
PMID: 19622587
Ref: The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion.
PMID: 20723226
Ref: Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1).
PMID: 21966428
Ref: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells.
PMID: 22968820
Ref: The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion.
PMID: 23242308
Ref: ncRuPAR inhibits gastric cancer progression by down-regulating protease-activated receptor-1.
PMID: 24817013
Ref: Thrombin conducts epithelialmesenchymal transition via proteaseactivated receptor1 in human gastric cancer.
PMID: 25231630
Ref: Overexpression of Plasminogen Activator Inhibitor-1 in Advanced Gastric Cancer with Aggressive Lymph Node Metastasis.
PMID: 25687870
Ref: Endothelial cell protein C receptor promotes MGC803 gastric cancer cells proliferation and migration by activating ERK1/2.
PMID: 25895599
Ref: PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway.
PMID: 26431277
Ref: Clinical significance of serum protease-activated receptor-1 levels in gastric cancer patients.
PMID: 27073639
Ref: Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner.
PMID: 29484413
Ref: EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis in vitro through activating ERK1/2 and AKT in a PAR1-dependent manner.
PMID: 30008838
Ref: The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells.
PMID: 30276573