Primary Site >> Colorectal Cancer
Gene >> F2R
| 1. | |||||||||||
| Journal: | Blood. 1998 Nov 15;92(10):3694-700. | ||||||||||
| Title: | Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis. | ||||||||||
| Author: | Nierodzik, M L|Chen, K|Takeshita, K|Li, J J|Huang, Y Q|Feng, X S|D'Andrea, M R|Andrade-Gordon, P|Karpatkin, S | ||||||||||
| PMID: | 9808563 | ||||||||||
| 2. | |||||||||||
| Journal: | Blood. 2000 May 15;95(10):3133-8. | ||||||||||
| Title: | Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells. | ||||||||||
| Author: | Zain, J|Huang, Y Q|Feng, X|Nierodzik, M L|Li, J J|Karpatkin, S | ||||||||||
| PMID: | 10807779 | ||||||||||
| 3. | |||||||||||
| Journal: | Am J Pathol. 2003 May;162(5):1503-13. | ||||||||||
| Title: | Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. | ||||||||||
| Author: | Darmoul, Dalila|Gratio, Valerie|Devaud, Helene|Lehy, Therese|Laburthe, Marc | ||||||||||
| PMID: | 12707033 | ||||||||||
| 4. | |||||||||||
| Journal: | Life Sci. 2003 Oct 17;73(22):2817-29. | ||||||||||
| Title: | MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2. | ||||||||||
| Author: | Jikuhara, Atsushi|Yoshii, Masanori|Iwagaki, Hiromi|Mori, Shuji|Nishibori, Masahiro|Tanaka, Noriaki | ||||||||||
| PMID: | 14511767 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cancer Res. 2004 Sep;2(9):514-22. | ||||||||||
| Title: | Activation of proteinase-activated receptor 1 promotes human colon cancer cell proliferation through epidermal growth factor receptor transactivation. | ||||||||||
| Author: | Darmoul, Dalila|Gratio, Valerie|Devaud, Helene|Peiretti, Franck|Laburthe, Marc | ||||||||||
| PMID: | 15383630 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncol Res. 2004;14(10):475-82. | ||||||||||
| Title: | PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. | ||||||||||
| Author: | Heider, Ilonka|Schulze, Beate|Oswald, Elke|Henklein, Peter|Scheele, Johannes|Kaufmann, Roland | ||||||||||
| PMID: | 15559761 | ||||||||||
| 7. | |||||||||||
| Journal: | J Pharmacol Sci. 2005 Jan;97(1):25-30. Epub 2005 Jan 15. | ||||||||||
| Title: | Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2-mediated proliferation of colon cancer cell. | ||||||||||
| Author: | Nishibori, Masahiro|Mori, Shuji|Takahashi, Hideo K | ||||||||||
| PMID: | 15655297 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncogene. 2005 Dec 15;24(56):8240-51. | ||||||||||
| Title: | Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment. | ||||||||||
| Author: | Nguyen, Quang-De|De Wever, Olivier|Bruyneel, Erik|Hendrix, An|Xie, Wan-Zhuo|Lombet, Alain|Leibl, Martin|Mareel, Marc|Gieseler, Frank|Bracke, Marc|Gespach, Christian | ||||||||||
| PMID: | 16091733 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2006 Aug 1;66(15):7766-74. | ||||||||||
| Title: | Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. | ||||||||||
| Author: | Goerge, Tobias|Barg, Alexej|Schnaeker, Eva-Maria|Poppelmann, Birgit|Shpacovitch, Victoria|Rattenholl, Anke|Maaser, Christian|Luger, Thomas A|Steinhoff, Martin|Schneider, Stefan W | ||||||||||
| PMID: | 16885380 | ||||||||||
| 10. | |||||||||||
| Journal: | Thromb Haemost. 2007 Aug;98(2):283-6. | ||||||||||
| Title: | Microfluidic reveals generation of platelet-strings on tumor-activated endothelium. | ||||||||||
| Author: | Goerge, Tobias|Kleineruschkamp, Felix|Barg, Alexej|Schnaeker, Eva-Maria|Huck, Volker|Schneider, Matthias F|Steinhoff, Martin|Schneider, Stefan W | ||||||||||
| PMID: | 17721608 | ||||||||||
| 11. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2008 Dec 12;377(2):622-6. | ||||||||||
| Title: | PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. | ||||||||||
| Author: | Tanaka, Yusuke|Sekiguchi, Fumiko|Hong, Hao|Kawabata, Atsufumi | ||||||||||
| PMID: | 18854173 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncol Rep. 2008 Nov;20(5):1069-76. | ||||||||||
| Title: | The expression and the functional roles of tissue factor and protease-activated receptor-2 on SW620 cells. | ||||||||||
| Author: | Zhou, Hong|Hu, Hongxin|Shi, Wenxia|Ling, Shucai|Wang, Ting|Wang, Haibo | ||||||||||
| PMID: | 18949403 | ||||||||||
| 13. | |||||||||||
| Journal: | Thromb Res. 2009 Jun;124(2):219-25. | ||||||||||
| Title: | Coagulation factor Xa inhibits cancer cell migration via protease-activated receptor-1 activation. | ||||||||||
| Author: | Borensztajn, Keren|Bijlsma, Maarten F|Reitsma, Pieter H|Peppelenbosch, Maikel P|Spek, C Arnold | ||||||||||
| PMID: | 19250659 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Exp Metastasis. 2009;26(3):171-8. | ||||||||||
| Title: | Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung. | ||||||||||
| Author: | Niers, Tatjana M H|Bruggemann, Lois W|Klerk, Clara P W|Muller, Femke J M|Buckle, Tessa|Reitsma, Pieter H|Richel, Dick J|Spek, C Arnold|Van Tellingen, Olaf|Van Noorden, Cornelis J F | ||||||||||
| PMID: | 19067186 | ||||||||||
| 15. | |||||||||||
| Journal: | Am J Pathol. 2010 Mar;176(3):1452-61. | ||||||||||
| Title: | Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells. | ||||||||||
| Author: | Gratio, Valerie|Beaufort, Nathalie|Seiz, Lina|Maier, Josefine|Virca, G Duke|Debela, Mekdes|Grebenchtchikov, Nicolai|Magdolen, Viktor|Darmoul, Dalila | ||||||||||
| PMID: | 20056842 | ||||||||||
| 16. | |||||||||||
| Journal: | Thromb Res. 2010 Jun;125(6):e323-8. | ||||||||||
| Title: | Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation. | ||||||||||
| Author: | Borensztajn, Keren|Peppelenbosch, Maikel P|Spek, C Arnold | ||||||||||
| PMID: | 20347121 | ||||||||||
| 17. | |||||||||||
| Journal: | J Med Chem. 2010 Oct 28;53(20):7428-40. | ||||||||||
| Title: | Novel agonists and antagonists for human protease activated receptor 2. | ||||||||||
| Author: | Barry, Grant D|Suen, Jacky Y|Le, Giang T|Cotterell, Adam|Reid, Robert C|Fairlie, David P | ||||||||||
| PMID: | 20873792 | ||||||||||
| 18. | |||||||||||
| Journal: | J Cell Physiol. 2011 Apr;226(4):1060-8. | ||||||||||
| Title: | Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1alpha translational pathway in colorectal cancer cells. | ||||||||||
| Author: | Chang, Li-Hsun|Chen, Chun-Han|Huang, Der-Yi|Pai, Hui-Chen|Pan, Shiow-Lin|Teng, Che-Ming | ||||||||||
| PMID: | 20857420 | ||||||||||
| 19. | |||||||||||
| Journal: | Am J Pathol. 2011 Nov;179(5):2625-36. | ||||||||||
| Title: | Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells. | ||||||||||
| Author: | Gratio, Valerie|Loriot, Celine|Virca, G Duke|Oikonomopoulou, Katerina|Walker, Francine|Diamandis, Eleftherios P|Hollenberg, Morley D|Darmoul, Dalila | ||||||||||
| PMID: | 21907696 | ||||||||||
| 20. | |||||||||||
| Journal: | Gastric Cancer. 2013 Jul;16(3):345-54. | ||||||||||
| Title: | Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells. | ||||||||||
| Author: | Mori, Ryutaro|Yoshida, Kazuhiro|Tanahashi, Toshiyuki|Yawata, Kazunori|Kato, Junko|Okumura, Naoki|Tsutani, Yasuhiro|Okada, Morihito|Oue, Naohide|Yasui, Wataru | ||||||||||
| PMID: | 22968820 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncol Rep. 2015 Jun;33(6):2681-8. | ||||||||||
| Title: | Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. | ||||||||||
| Author: | Jia, Yitao|Zhang, Suqiao|Miao, Lingling|Wang, Jingbao|Jin, Zujian|Gu, Bin|Duan, Zhihui|Zhao, Zhaolong|Ma, Shunmao|Zhang, Wenjin|Li, Zhongxin | ||||||||||
| PMID: | 25846512 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2015 Oct 1;75(19):4235-43. | ||||||||||
| Title: | Colon Cancer Growth and Dissemination Relies upon Thrombin, Stromal PAR-1, and Fibrinogen. | ||||||||||
| Author: | Adams, Gregory N|Rosenfeldt, Leah|Frederick, Malinda|Miller, Whitney|Waltz, Dusty|Kombrinck, Keith|McElhinney, Kathryn E|Flick, Matthew J|Monia, Brett P|Revenko, Alexey S|Palumbo, Joseph S | ||||||||||
| PMID: | 26238780 | ||||||||||
| 23. | |||||||||||
| Journal: | Onco Targets Ther. 2015 Aug 27;8:2291-301. | ||||||||||
| Title: | Genetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy. | ||||||||||
| Author: | Zhang, Hui|Wang, Mengyun|Shi, Tingyan|Shen, Lijun|Zhu, Ji|Sun, Menghong|Deng, Yun|Liang, Liping|Li, Guichao|Wu, Yongxin|Fan, Ming|Wei, Qingyi|Zhang, Zhen | ||||||||||
| PMID: | 26347502 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncol Rep. 2016 Feb;35(2):1222. | ||||||||||
| Title: | [Corrigendum] Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. | ||||||||||
| Author: | Jia, Yitao|Zhang, Suqiao|Miao, Lingling|Wang, Jingbao|Jin, Zujian|Gu, Bin|Duan, Zhihui|Zhao, Zhaolong|Ma, Shunmao|Zhang, Wenjin|Li, Zhongxin | ||||||||||
| PMID: | 26718652 | ||||||||||
| 25. | |||||||||||
| Journal: | Thromb Res. 2016 Apr;140 Suppl 1:S195. | ||||||||||
| Title: | PO-51 - Expression of proteins of the tissue factor thrombin pathway is upregulated in the stroma and epithelium of colorectal cancer. | ||||||||||
| Author: | Clouston, H W|Davenport, A|Gregson, H|Shaker, H|Duff, S|Kirwan, C C | ||||||||||
| PMID: | 27161738 | ||||||||||
| 26. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G221-36. | ||||||||||
| Title: | PAR2-dependent activation of GSK3beta regulates the survival of colon stem/progenitor cells. | ||||||||||
| Author: | Nasri, Imen|Bonnet, Delphine|Zwarycz, Bailey|d'Aldebert, Emilie|Khou, Sokchea|Mezghani-Jarraya, Raoudha|Quaranta, Muriel|Rolland, Corinne|Bonnart, Chrystelle|Mas, Emmanuel|Ferrand, Audrey|Cenac, Nicolas|Magness, Scott|Van Landeghem, Laurianne|Vergnolle, N | ||||||||||
| PMID: | 27313176 | ||||||||||
| 27. | |||||||||||
| Journal: | Apoptosis. 2018 Sep 8. pii: 10.1007/s10495-018-1485-4. | ||||||||||
| Title: | Molecular targeting of breast and colon cancer cells by PAR1 mediated apoptosis through a novel pro-apoptotic peptide. | ||||||||||
| Author: | Ray, Tanusree|Kar, Dwiprohi|Pal, Ananda|Mukherjee, Shravanti|Das, Chandrima|Pal, Amit | ||||||||||
| PMID: | 30196356 | ||||||||||