Primary Site >> Liver Cancer

Gene >> EZH2

Journal: Br J Cancer. 2005 May 9;92(9):1754-8.
Title: Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma.
Author: Sudo, T|Utsunomiya, T|Mimori, K|Nagahara, H|Ogawa, K|Inoue, H|Wakiyama, S|Fujita, H|Shirouzu, K|Mori, M
PMID: 15856046
Journal: Br J Cancer. 2006 Nov 6;95(9):1202-11.
Title: The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.
Author: Steele, J C|Torr, E E|Noakes, K L|Kalk, E|Moss, P A|Reynolds, G M|Hubscher, S G|van Lohuizen, M|Adams, D H|Young, L S
PMID: 17024127
Journal: Hepatol Res. 2007 Nov;37(11):974-83.
Title: Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.
Author: Kondo, Yutaka|Shen, Lanlan|Suzuki, Seiji|Kurokawa, Tsuyoshi|Masuko, Kazuo|Tanaka, Yasuhito|Kato, Hideaki|Mizuno, Yoshiki|Yokoe, Masamichi|Sugauchi, Fuminaka|Hirashima, Noboru|Orito, Etsuro|Osada, Hirotaka|Ueda, Ryuzo|Guo, Yi|Chen, Xinli|Issa, Jean-Pierre
PMID: 17584191
Journal: Hepatology. 2007 Jul;46(1):200-8.
Title: Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.
Author: Chen, Yangchao|Lin, Marie C|Yao, Hong|Wang, Hua|Zhang, Ai-Qun|Yu, Jun|Hui, Chee-kin|Lau, George K|He, Ming-liang|Sung, Joseph|Kung, Hsiang-fu
PMID: 17596871
Journal: Proteomics. 2007 Sep;7(17):3097-104.
Title: Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma.
Author: Chen, Yangchao|Lin, Marie Chia-mi|Wang, Hua|Chan, Chu-yan|Jiang, Lei|Ngai, Sai Ming|Yu, Jun|He, Ming-liang|Shaw, Pang-Chui|Yew, David T|Sung, Joseph J|Kung, Hsiang-fu
PMID: 17676662
Journal: Lab Invest. 2008 Aug;88(8):873-82.
Title: The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma.
Author: Sasaki, Motoko|Ikeda, Hiroko|Itatsu, Keita|Yamaguchi, Junpei|Sawada, Seiko|Minato, Hiroshi|Ohta, Tetsuo|Nakanuma, Yasuni
PMID: 18591938
Journal: Hum Pathol. 2009 Sep;40(9):1304-11.
Title: Distinct expression of polycomb group proteins EZH2 and BMI1 in hepatocellular carcinoma.
Author: Yonemitsu, Yutaka|Imazeki, Fumio|Chiba, Tetsuhiro|Fukai, Kenichi|Nagai, Yuichiro|Miyagi, Satoru|Arai, Makoto|Aoki, Ryutaro|Miyazaki, Masaru|Nakatani, Yukio|Iwama, Atsushi|Yokosuka, Osamu
PMID: 19386347
Journal: J Biomed Sci. 2010 May 6;17:35.
Title: PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells.
Author: Chiang, Chao-Wei|Huang, Yi|Leong, Ka-Wai|Chen, Lih-Chyang|Chen, Hua-Chien|Chen, Shu-Jen|Chou, Chen-Kung
PMID: 20444294
Journal: Cancer Lett. 2010 Nov 1;297(1):109-16.
Title: RNAi targeting EZH2 inhibits tumor growth and liver metastasis of pancreatic cancer in vivo.
Author: Chen, Yangchao|Xie, Dan|Yin Li, Wing|Man Cheung, Chi|Yao, Hong|Chan, Ching Yu|Chan, Chu-yan|Xu, Fang-Ping|Liu, Yan-Hui|Sung, Joseph J Y|Kung, Hsiang-fu
PMID: 20684863
Journal: Carcinogenesis. 2011 Jan;32(1):2-9.
Title: Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer.
Author: Zhang, Bo|Liu, Xiao-Xiao|He, Jian-Rong|Zhou, Ci-Xiang|Guo, Meng|He, Ming|Li, Mei-Fang|Chen, Guo-Qiang|Zhao, Qian
PMID: 20952513
Journal: Gut. 2011 Jul;60(7):967-76.
Title: EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies.
Author: Cai, Mu-Yan|Tong, Zhu-Ting|Zheng, Fang|Liao, Yi-Ji|Wang, Yi|Rao, Hui-Lan|Chen, Yang-Chao|Wu, Qiu-Liang|Liu, Yan-Hui|Guan, Xin-Yuan|Lin, Marie C|Zeng, Yi-Xin|Kung, Hsiang-Fu|Xie, Dan
PMID: 21330577
Journal: Oncogene. 2011 Jun 9;30(23):2670-8.
Title: p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.
Author: Testoni, B|Schinzari, V|Guerrieri, F|Gerbal-Chaloin, S|Blandino, G|Levrero, M
PMID: 21399658
Journal: Chin J Cancer. 2011 Apr;30(4):273-9.
Title: Hepatitis B virus X protein regulates the mEZH2 promoter via the E2F1-binding site in AML12 cells.
Author: Shi, Xiao-Yan|Zhang, Ying-Ying|Zhou, Xiao-Wei|Lu, Jian-Sheng|Guo, Ze-Kun|Huang, Pei-Tang
PMID: 21439249
Journal: Cancer Res. 2011 Jun 1;71(11):4028-39.
Title: EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis.
Author: Cheng, Alfred S L|Lau, Suki S|Chen, Yangchao|Kondo, Yutaka|Li, May S|Feng, Hai|Ching, Arthur K|Cheung, Kin F|Wong, Hoi K|Tong, Joanna H|Jin, Hongchuan|Choy, Kwong W|Yu, Jun|To, Ka F|Wong, Nathalie|Huang, Tim H-M|Sung, Joseph J Y
PMID: 21512140
Journal: Hepatology. 2011 Nov;54(5):1679-89.
Title: Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans.
Author: Yang, Fu|Zhang, Ling|Huo, Xi-song|Yuan, Ji-hang|Xu, Dan|Yuan, Sheng-xian|Zhu, Nan|Zhou, Wei-ping|Yang, Guang-shun|Wang, Yu-zhao|Shang, Jing-li|Gao, Chun-fang|Zhang, Feng-rui|Wang, Fang|Sun, Shu-han
PMID: 21769904
Journal: Gut. 2012 Feb;61(2):278-89.
Title: The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2.
Author: Zheng, Fang|Liao, Yi-Ji|Cai, Mu-Yan|Liu, Yan-Hui|Liu, Tian-Hao|Chen, Shu-Peng|Bian, Xiu-Wu|Guan, Xin-Yuan|Lin, Marie C|Zeng, Yi-Xin|Kung, Hsiang-Fu|Xie, Dan
PMID: 21672940
Journal: Int J Cancer. 2012 Jun 1;130(11):2557-67.
Title: 3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells.
Author: Chiba, Tetsuhiro|Suzuki, Eiichiro|Negishi, Masamitsu|Saraya, Atsunori|Miyagi, Satoru|Konuma, Takaaki|Tanaka, Satomi|Tada, Motohisa|Kanai, Fumihiko|Imazeki, Fumio|Iwama, Atsushi|Yokosuka, Osamu
PMID: 21717453
Journal: Hepatology. 2012 Aug;56(2):622-31.
Title: Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis.
Author: Au, Sandy Leung-Kuen|Wong, Carmen Chak-Lui|Lee, Joyce Man-Fong|Fan, Dorothy Ngo-Yin|Tsang, Felice Hoching|Ng, Irene Oi-Lin|Wong, Chun-Ming
PMID: 22370893
Journal: Exp Mol Pathol. 2012 Jun;92(3):318-26.
Title: Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.
Author: French, B A|Oliva, J|Bardag-Gorce, F|Li, J|Zhong, J|Buslon, V|French, S W
PMID: 22465358
Journal: Diagn Pathol. 2012 Jul 18;7:86.
Title: Enhancer of zeste homologue 2 (EZH2) is a reliable immunohistochemical marker to differentiate malignant and benign hepatic tumors.
Author: Hajosi-Kalcakosz, Szofia|Dezso, Katalin|Bugyik, Edina|Bodor, Csaba|Paku, Sandor|Pavai, Zoltan|Halasz, Judit|Schlachter, Krisztina|Schaff, Zsuzsa|Nagy, Peter
PMID: 22809481
Journal: PLoS One. 2012;7(9):e44206.
Title: MiR-214 targets beta-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.
Author: Xia, Hongping|Ooi, London Lucien P J|Hui, Kam M
PMID: 22962603
Journal: OMICS. 2012 Nov;16(11):579-88.
Title: Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma.
Author: Poma, Paola|Labbozzetta, Manuela|Vivona, Nicoletta|Porcasi, Rossana|D'Alessandro, Natale|Notarbartolo, Monica
PMID: 23095110
Journal: Oncogene. 2013 Mar 28;32(13):1616-25.
Title: HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.
Author: Kim, K|Jutooru, I|Chadalapaka, G|Johnson, G|Frank, J|Burghardt, R|Kim, S|Safe, S
PMID: 22614017
Journal: Oncol Rep. 2013 Mar;29(3):1037-42.
Title: RNAi-mediated EZH2 depletion decreases MDR1 expression and sensitizes multidrug-resistant hepatocellular carcinoma cells to chemotherapy.
Author: Tang, Bo|Zhang, Yi|Liang, Rui|Gao, Zhenming|Sun, Deguang|Wang, Liming
PMID: 23291714
Journal: N Biotechnol. 2013 May 25;30(4):381-4.
Title: Genetics and epigenetics of liver cancer.
Author: Ozen, Cigdem|Yildiz, Gokhan|Dagcan, Alper Tunga|Cevik, Dilek|Ors, Aysegul|Keles, Umur|Topel, Hande|Ozturk, Mehmet
PMID: 23392071
Journal: Cancer Sci. 2013 Jun;104(6):750-9.
Title: Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2.
Author: Wang, Shanshan|Zhu, Yu|He, Hongyong|Liu, Jing|Xu, Le|Zhang, Heng|Liu, Haiou|Liu, Weisi|Liu, Yidong|Pan, Deng|Chen, Lin|Wu, Qian|Xu, Jiejie|Gu, Jianxin
PMID: 23421437
Journal: Pathol Res Pract. 2013 Apr;209(4):249-54.
Title: Primary liver sarcomatous carcinoma: report of two cases and review of the literature.
Author: Giunchi, Francesca|Vasuri, Francesco|Baldin, Pamela|Rosini, Francesca|Corti, Barbara|D'Errico-Grigioni, Antonia
PMID: 23484778
Journal: Eur J Surg Oncol. 2013 Jun;39(6):655-61.
Title: Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancer.
Author: Tamagawa, H|Oshima, T|Numata, M|Yamamoto, N|Shiozawa, M|Morinaga, S|Nakamura, Y|Yoshihara, M|Sakuma, Y|Kameda, Y|Akaike, M|Yukawa, N|Rino, Y|Masuda, M|Miyagi, Y
PMID: 23523318
Journal: Life Sci. 2013 May 20;92(17-19):896-902.
Title: Silencing the EZH2 gene by RNA interference reverses the drug resistance of human hepatic multidrug-resistant cancer cells to 5-Fu.
Author: Zhang, Yi|Liu, Guangpu|Lin, Changwei|Liao, Guoqing|Tang, Bo
PMID: 23562851
Journal: Front Med. 2013 Jun;7(2):231-41.
Title: Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins.
Author: Au, Sandy Leung-Kuen|Ng, Irene Oi-Lin|Wong, Chun-Ming
PMID: 23620257
Journal: Mol Cancer Ther. 2013 Aug;12(8):1651-64.
Title: Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.
Author: Sia, Kian Chuan|Huynh, Hung|Chung, Alexander Yaw Fui|Ooi, London Lucien Peng Jin|Lim, Kiat Hon|Hui, Kam Man|Lam, Paula Yeng Po
PMID: 23720769
Journal: PLoS One. 2013 Jun 27;8(6):e68226.
Title: EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers.
Author: Au, Sandy Leung-Kuen|Wong, Carmen Chak-Lui|Lee, Joyce Man-Fong|Wong, Chun-Ming|Ng, Irene Oi-Lin
PMID: 23826380
Journal: PLoS One. 2013 Sep 10;8(9):e74870.
Title: Effects of EZH2 polymorphisms on susceptibility to and pathological development of hepatocellular carcinoma.
Author: Yu, Yung-Luen|Su, Kuo-Jung|Hsieh, Yi-Hsien|Lee, Hsiang-Lin|Chen, Tzy-Yen|Hsiao, Pei-Ching|Yang, Shun-Fa
PMID: 24040354
Journal: BMC Med Genomics. 2013 Sep 30;6:35.
Title: Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers.
Author: Cohen, Adam L|Piccolo, Stephen R|Cheng, Luis|Soldi, Rafaella|Han, Bing|Johnson, W Evan|Bild, Andrea H
PMID: 24079712
Journal: Hepatobiliary Surg Nutr. 2013 Apr;2(2):78-83.
Title: Effects of EZH2 gene on the growth and migration of hepatocellular carcinoma HepG2 cells.
Author: Zhao, Hongtao|Xu, Yiyao|Mao, Yilei|Zhang, Yangde
PMID: 24570920
Journal: Tumour Biol. 2014 Jan;35(1):205-12.
Title: A potential antitumor ellagitannin, davidiin, inhibited hepatocellular tumor growth by targeting EZH2.
Author: Wang, Yan|Ma, Jingyi|Chow, Sheung Ching|Li, Chi Han|Xiao, Zhangang|Feng, Ru|Fu, Jie|Chen, Yangchao
PMID: 23897557
Journal: Hepatology. 2014 May;59(5):1850-63.
Title: c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma.
Author: Wang, Lei|Zhang, Xiang|Jia, Lin-Tao|Hu, Si-Jun|Zhao, Jing|Yang, Jian-Dong|Wen, Wei-Hong|Wang, Zhe|Wang, Tao|Zhao, Jun|Wang, Rui-An|Meng, Yan-Ling|Nie, Yong-Zhan|Dou, Ke-Feng|Chen, Si-Yi|Yao, Li-Bo|Fan, Dai-Ming|Zhang, Rui|Yang, An-Gang
PMID: 24002871
Journal: Carcinogenesis. 2014 Jan;35(1):53-61.
Title: Telbivudine treatment corrects HBV-induced epigenetic alterations in liver cells of patients with chronic hepatitis B.
Author: Tian, Yi|Ni, Dongjing|Yang, Weibing|Zhang, Yi|Zhao, Keji|Song, Jianxun|Mao, Qing|Tian, Zhiqiang|van Velkinburgh, Jennifer C|Yang, Di|Wu, Yuzhang|Ni, Bing
PMID: 24067902
Journal: J Hepatol. 2014 Mar;60(3):590-8.
Title: MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity.
Author: Xu, Leibo|Beckebaum, Susanne|Iacob, Speranta|Wu, Gang|Kaiser, Gernot M|Radtke, Arnold|Liu, Chao|Kabar, Iyad|Schmidt, Hartmut H|Zhang, Xiaoyong|Lu, Mengji|Cicinnati, Vito R
PMID: 24211739
Journal: J Hepatol. 2014 Oct;61(4):832-9.
Title: The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Xu, Bin|Ding, Li-Hong|Zheng, Qi-Lin|Zhang, Li|Zheng, Qi-Fan|Li, Shan-Hua|Feng, Zi-Jie|Wei, Jie|Yin, Zhen-Yu|Hua, Xianxin|Jin, Guang-Hui
PMID: 24845612
Journal: Oncogenesis. 2014 May 26;3:e104.
Title: Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells.
Author: Hibino, S|Saito, Y|Muramatsu, T|Otani, A|Kasai, Y|Kimura, M|Saito, H
PMID: 24861464
Journal: Mol Cancer Res. 2014 Oct;12(10):1388-97.
Title: EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Zheng, Qi-Fan|Xu, Bin|Pan, Chang-Bao|Li, Kang-Li|Zhao, Yue|Zheng, Qi-Lin|Lin, Xiao|Xue, Li-Xiang|Jin, Guang-Hui
PMID: 24916103
Journal: Int J Clin Exp Pathol. 2014 Apr 15;7(5):2496-507. eCollection 2014.
Title: Histone-modifying genes as biomarkers in hepatocellular carcinoma.
Author: Hung, Shih-Ya|Lin, Hui-Hua|Yeh, Kun-Tu|Chang, Jan-Gowth
PMID: 24966962
Journal: PLoS One. 2014 Sep 16;9(9):e107251.
Title: Aberrant upregulation of 14-3-3sigma and EZH2 expression serves as an inferior prognostic biomarker for hepatocellular carcinoma.
Author: Zhang, Yi|Li, Yang|Lin, Changwei|Ding, Jie|Liao, Guoqing|Tang, Bo
PMID: 25226601
Journal: Int J Clin Exp Med. 2014 Nov 15;7(11):4038-50. eCollection 2014.
Title: Regulation of gene expression in HBV- and HCV-related hepatocellular carcinoma: integrated GWRS and GWGS analyses.
Author: Zhou, Xu|Zhu, Hua-Qiang|Lu, Jun
PMID: 25550913
Journal: Genet Test Mol Biomarkers. 2015 Jan;19(1):30-6.
Title: miR-26a promoted by interferon-alpha inhibits hepatocellular carcinoma proliferation and migration by blocking EZH2.
Author: Wang, Gang|Sun, Yubei|He, Yifu|Ji, Chushu|Hu, Bing|Sun, Yuping
PMID: 25494962
Journal: J Hepatol. 2015 May;62(5):1100-11.
Title: A CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients.
Author: Feng, Hai|Yu, Zhuo|Tian, Yuan|Lee, Ying-Ying|Li, May S|Go, Minnie Y Y|Cheung, Yue-Sun|Lai, Paul B S|Chan, Andrew M L|To, Ka-Fai|Chan, Henry L Y|Sung, Joseph J Y|Cheng, Alfred S L
PMID: 25500144
Journal: J Invest Dermatol. 2015 Apr;135(4):960-969.
Title: miR-214 as a key hub that controls cancer networks: small player, multiple functions.
Author: Penna, Elisa|Orso, Francesca|Taverna, Daniela
PMID: 25501033
Journal: Cancer Lett. 2015 Apr 10;359(2):198-205.
Title: DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
Author: Ning, Xianghong|Shi, Zhendong|Liu, Xi|Zhang, Anling|Han, Lei|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu
PMID: 25595591
Journal: J Pathol. 2015 May;236(1):1-4.
Title: CUL4B: a novel epigenetic driver in Wnt/beta-catenin-dependent hepatocarcinogenesis.
Author: Mok, Myth T S|Cheng, Alfred S L
PMID: 25664533
Journal: PLoS Genet. 2015 Feb 18;11(2):e1004873.
Title: Systemic delivery of microRNA-101 potently inhibits hepatocellular carcinoma in vivo by repressing multiple targets.
Author: Zheng, Fang|Liao, Yi-Ji|Cai, Mu-Yan|Liu, Tian-Hao|Chen, Shu-Peng|Wu, Pei-Hong|Wu, Long|Bian, Xiu-Wu|Guan, Xin-Yuan|Zeng, Yi-Xin|Yuan, Yun-Fei|Kung, Hsiang-Fu|Xie, Dan
PMID: 25693145
Journal: J Hepatol. 2015 Oct;63(4):886-95.
Title: Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling.
Author: Fu, Wei-Ming|Zhu, Xiao|Wang, Wei-Mao|Lu, Ying-Fei|Hu, Bao-Guang|Wang, Hua|Liang, Wei-Cheng|Wang, Shan-Shan|Ko, Chun-Hay|Waye, Mary Miu-Yee|Kung, Hsiang-Fu|Li, Gang|Zhang, Jin-Fang
PMID: 26024833
Journal: Int J Clin Exp Pathol. 2015 May 1;8(5):4972-80. eCollection 2015.
Title: MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2.
Author: Liu, Fenghua|He, Yukai|Shu, Ronghua|Wang, Sikui
PMID: 26191190
Journal: Med Oncol. 2015 Sep;32(9):226.
Title: Long noncoding RNA-LET, which is repressed by EZH2, inhibits cell proliferation and induces apoptosis of nasopharyngeal carcinoma cell.
Author: Sun, Qiuzhen|Liu, Hongbing|Li, Lihua|Zhang, Shaorong|Liu, Ke|Liu, Yuehui|Yang, Chunping
PMID: 26243049
Journal: Cancer Res. 2015 Nov 15;75(22):4803-16.
Title: Histone Deacetylase HDAC8 Promotes Insulin Resistance and beta-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma.
Author: Tian, Yuan|Wong, Vincent W S|Wong, Grace L H|Yang, Weiqin|Sun, Hanyong|Shen, Jiayun|Tong, Joanna H M|Go, Minnie Y Y|Cheung, Yue S|Lai, Paul B S|Zhou, Mingyan|Xu, Gang|Huang, Tim H M|Yu, Jun|To, Ka F|Cheng, Alfred S L|Chan, Henry L Y
PMID: 26383163
Journal: Nat Commun. 2015 Sep 25;6:8494.
Title: EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma.
Author: Liu, Haiou|Liu, Yidong|Liu, Weisi|Zhang, Weijuan|Xu, Jiejie
PMID: 26404566
Journal: Oncotarget. 2015 Nov 24;6(37):39865-76.
Title: Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.
Author: Jiang, Yunyun|Malouf, Gabriel G|Zhang, Jianping|Zheng, Xiaofeng|Chen, Yunxin|Thompson, Erika J|Weinstein, John N|Yuan, Ying|Spano, Jean-Philippe|Broaddus, Russell|Tannir, Nizar M|Khayat, David|Lu, Karen H|Su, Xiaoping
PMID: 26431491
Journal: J Biol Chem. 2015 Nov 20;290(47):28489-501.
Title: Tumor Suppressive Function of p21-activated Kinase 6 in Hepatocellular Carcinoma.
Author: Liu, Weisi|Liu, Yidong|Liu, Haiou|Zhang, Weijuan|Fu, Qiang|Xu, Jiejie|Gu, Jianxin
PMID: 26442588
Journal: Oncotarget. 2015 Dec 1;6(38):40940-52.
Title: Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma.
Author: Xie, Cheng-Rong|Li, Zhao|Sun, Hong-Guang|Wang, Fu-Qiang|Sun, Yu|Zhao, Wen-Xiu|Zhang, Sheng|Zhao, Wen-Xing|Wang, Xiao-Min|Yin, Zhen-Yu
PMID: 26517514
Journal: Am J Cancer Res. 2015 Sep 15;5(10):2969-79. eCollection 2015.
Title: Genetic alteration and misexpression of Polycomb group genes in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Sun, Shi-Long|Zheng, Qi-Lin|Zhang, Li|Zhu, Yuequan|Jin, Guang-Hui|Xue, Li-Xiang
PMID: 26693053
Journal: Oncogene. 2016 Feb 11;35(6):715-26.
Title: Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2.
Author: Fan, H|Zhang, H|Pascuzzi, P E|Andrisani, O
PMID: 25893293
Journal: J Hepatol. 2016 Jan;64(1):87-93.
Title: Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications.
Author: Sciarra, Amedeo|Di Tommaso, Luca|Nakano, Masayuki|Destro, Annarita|Torzilli, Guido|Donadon, Matteo|Maggioni, Marco|Bosari, Silvano|Bulfamante, Gaetano|Matsuda, Masanori|Fujii, Hideki|Ichikawa, Tomoaki|Morisaka, Hiroyuki|Sano, Katsuhiro|Ichikawa, Shintaro|
PMID: 26343958
Journal: Oncol Rep. 2016 Feb;35(2):1083-90.
Title: Reciprocal negative feedback loop between EZH2 and miR-101-1 contributes to miR-101 deregulation in hepatocellular carcinoma.
Author: Huang, Da|Wang, Xiaobei|Zhuang, Chunbo|Shi, Wuhe|Liu, Mu|Tu, Qiming|Zhang, Detai|Hu, Lihua
PMID: 26718325
Journal: J Hematol Oncol. 2016 Jan 6;9:1.
Title: MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2.
Author: Ma, De-Ning|Chai, Zong-Tao|Zhu, Xiao-Dong|Zhang, Ning|Zhan, Di-Hua|Ye, Bo-Gen|Wang, Cheng-Hao|Qin, Cheng-Dong|Zhao, Yi-Ming|Zhu, Wei-Ping|Cao, Man-Qing|Gao, Dong-Mei|Sun, Hui-Chuan|Tang, Zhao-You
PMID: 26733151
Journal: J Pathol. 2016 Apr;238(5):651-64.
Title: Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-kappaB in hepatocellular carcinoma.
Author: Tsang, Daisy P F|Wu, William K K|Kang, Wei|Lee, Ying-Ying|Wu, Feng|Yu, Zhuo|Xiong, Lei|Chan, Anthony W|Tong, Joanna H|Yang, Weiqin|Li, May S M|Lau, Suki S|Li, Xiangchun|Lee, Sau-Dan|Yang, Yihua|Lai, Paul B S|Yu, Dae-Yeul|Xu, Gang|Lo, Kwok-Wai|Chan, Matthe
PMID: 26800240
Journal: Mol Med Rep. 2016 Mar;13(3):2724-8.
Title: Enhancer of zeste homolog 2 depletion arrests the proliferation of hepatoblastoma cells.
Author: Wang, Yue|Xiao, Yongtao|Chen, Kai|Chen, Sheng|Zhang, Min|Wu, Zhixiang|Wu, Yeming
PMID: 26848027
Journal: Oncoscience. 2016 Jan 29;3(1):9-20.
Title: In silico and experimental analyses predict the therapeutic value of an EZH2 inhibitor GSK343 against hepatocellular carcinoma through the induction of metallothionein genes.
Author: Liu, Tsang-Pai|Hong, Yi-Han|Tung, Kwang-Yi|Yang, Pei-Ming
PMID: 26973856
Journal: J Mol Cell Biol. 2016 Mar 21. pii: mjw010.
Title: microRNA-129-5p, a c-Myc negative target, affects hepatocellular carcinoma progression by blocking the Warburg effect.
Author: Han, Han|Li, Wenjuan|Shen, Hongxing|Zhang, Jinxiang|Zhu, Yahui|Li, Youjun
PMID: 27001970
Journal: Carcinogenesis. 2016 Jun;37(6):557-566.
Title: CLDN14 is epigenetically silenced by EZH2-mediated H3K27ME3 and is a novel prognostic biomarker in hepatocellular carcinoma.
Author: Li, Chang-Peng|Cai, Mu-Yan|Jiang, Li-Juan|Mai, Shi-Juan|Chen, Jie-Wei|Wang, Feng-Wei|Liao, Yi-Ji|Chen, Wen-Hui|Jin, Xiao-Han|Pei, Xiao-Qing|Guan, Xin-Yuan|Zeng, Mu-Sheng|Xie, Dan
PMID: 27207647
Journal: Sci Rep. 2016 May 27;6:26971.
Title: The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells.
Author: Li, Jie|Zhang, Sheng|Hu, Qing|Zhang, Kang|Jin, Jianbin|Zheng, Xuqing|Yin, Zhenyu|Wang, Xiaomin
PMID: 27231134
Journal: Nat Struct Mol Biol. 2016 Jul;23(7):631-9.
Title: lnc-beta-Catm elicits EZH2-dependent beta-catenin stabilization and sustains liver CSC self-renewal.
Author: Zhu, Pingping|Wang, Yanying|Huang, Guanling|Ye, Buqing|Liu, Benyu|Wu, Jiayi|Du, Ying|He, Lei|Fan, Zusen
PMID: 27239797
Journal: Oncotarget. 2016 Aug 2;7(31):50131-50149.
Title: Inflammatory related gene IKKalpha, IKKbeta, IKKgamma cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis.
Author: An, Jiahui|Wu, Mengying|Xin, Xiaoru|Lin, Zhuojia|Li, Xiaonan|Zheng, Qidi|Gui, Xin|Li, Tianming|Pu, Hu|Li, Haiyan|Lu, Dongdong
PMID: 27367027
Journal: J Mol Med (Berl). 2016 Nov;94(11):1281-1296.
Title: Long noncoding RNA GIHCG promotes hepatocellular carcinoma progression through epigenetically regulating miR-200b/a/429.
Author: Sui, Cheng-Jun|Zhou, Yan-Ming|Shen, Wei-Feng|Dai, Bing-Hua|Lu, Jiong-Jiong|Zhang, Min-Feng|Yang, Jia-Mei
PMID: 27380494
Journal: Gene. 2016 Oct 30;592(1):172-178.
Title: Long noncoding RNA HULC promotes colorectal carcinoma progression through epigenetically repressing NKD2 expression.
Author: Yang, Xiao-Jun|Huang, Chao-Qun|Peng, Chun-Wei|Hou, Jin-Xuan|Liu, Jiu-Yang
PMID: 27496341
Journal: Biochem Biophys Res Commun. 2016 Sep 16;478(2):811-7.
Title: Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression.
Author: Fang, Jing|Sun, Cheng-Cao|Gong, Cheng
PMID: 27501756
Journal: Tumour Biol. 2016 Nov;37(11):14903-14914.
Title: Hypoxia-induced NIPP1 activation enhances metastatic potential and predicts poor prognosis in hepatocellular carcinoma.
Author: Huang, Yun|Tao, Yiming|Hu, Kuan|Lin, Feng|Li, Xinying|Feng, Tiecheng|Wang, Zhi-Ming
PMID: 27644248
Journal: Onco Targets Ther. 2016 Nov 24;9:6987-6998.
Title: The relationship between the expression of USP22, BMI1, and EZH2 in hepatocellular carcinoma and their impacts on prognosis.
Author: Zhai, Run|Tang, Fang|Gong, Jianhua|Zhang, Jing|Lei, Biao|Li, Bo|Wei, Yangchao|Liang, Xingsi|Tang, Bo|He, Songqing
PMID: 27920552
Journal: Oncotarget. 2017 Jun 13;8(24):38227-38238.
Title: Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression.
Author: Nie, Fengqi|Yu, Xiang|Huang, Mingde|Wang, Yunfei|Xie, Min|Ma, Hongwei|Wang, Zhaoxia|De, Wei|Sun, Ming
PMID: 27246976
Journal: Oncogene. 2017 Apr 6;36(14):2030-2044.
Title: A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets.
Author: Wijetunga, N A|Pascual, M|Tozour, J|Delahaye, F|Alani, M|Adeyeye, M|Wolkoff, A W|Verma, A|Greally, J M
PMID: 27721404
Journal: Biomed Pharmacother. 2017 Jan;85:472-478.
Title: miR-98 inhibits hepatocellular carcinoma cell proliferation via targeting EZH2 and suppressing Wnt/beta-catenin signaling pathway.
Author: Zhang, Jun-Jie|Chen, Jiang-Tao|Hua, Long|Yao, Kun-Hou|Wang, Chen-Yu
PMID: 27890434
Journal: Biomed Pharmacother. 2017 Jan;85:348-354.
Title: Overexpression of the long non-coding RNA SPRY4-IT1 promotes tumor cell proliferation and invasion by activating EZH2 in hepatocellular carcinoma.
Author: Zhou, Meng|Zhang, Xiao-Yu|Yu, Xi
PMID: 27899259
Journal: Biomed Pharmacother. 2017 May;89:857-863.
Title: Long non-coding RNA SNHG20 predicts a poor prognosis for HCC and promotes cell invasion by regulating the epithelial-to-mesenchymal transition.
Author: Liu, Jinxia|Lu, Cuihua|Xiao, Mingbing|Jiang, Feng|Qu, Lishuai|Ni, Runzhou
PMID: 28282787
Journal: Biomed Pharmacother. 2017 May;89:926-932.
Title: Long non-coding RNA HNF1A-AS1 promotes hepatocellular carcinoma cell proliferation by repressing NKD1 and P21 expression.
Author: Wang, Cong|Mou, Lin|Chai, Hai-Xia|Wang, Feng|Yin, Yun-Zhi|Zhang, Xiao-Yu
PMID: 28292020
Journal: Cell Death Differ. 2017 May;24(5):889-902.
Title: Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.
Author: Gnani, Daniela|Romito, Ilaria|Artuso, Simona|Chierici, Marco|De Stefanis, Cristiano|Panera, Nadia|Crudele, Annalisa|Ceccarelli, Sara|Carcarino, Elena|D'Oria, Valentina|Porru, Manuela|Giorda, Ezio|Ferrari, Karin|Miele, Luca|Villa, Erica|Balsano, Clara|Pasi
PMID: 28338656
Journal: Biomed Pharmacother. 2017 Jun;90:100-108.
Title: Linc00152 promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma.
Author: Deng, Xin|Zhao, Xiao Fang|Liang, Xing Qiu|Chen, Ran|Pan, Yi Feng|Liang, Jian
PMID: 28343069
Journal: Mol Oncol. 2017 Sep;11(9):1225-1240.
Title: HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis.
Author: Chen, Shi-Lu|Liu, Li-Li|Lu, Shi-Xun|Luo, Rong-Zhen|Wang, Chun-Hua|Wang, Hong|Cai, Shao-Hang|Yang, Xia|Xie, Dan|Zhang, Chris Zhiyi|Yun, Jing-Ping
PMID: 28580773
Journal: Biol Open. 2017 Sep 15;6(9):1310-1316.
Title: Targeting long non-coding RNA DANCR inhibits triple negative breast cancer progression.
Author: Sha, Sha|Yuan, Dongya|Liu, Yuejun|Han, Baosan|Zhong, Nanbert
PMID: 28760736
Journal: Cancer Biomark. 2017 Dec 6;20(4):511-519.
Title: Long noncoding RNA PVT1 promotes hepatocellular carcinoma progression through regulating miR-214.
Author: Gou, Xun|Zhao, Xiyan|Wang, Zhengrong
PMID: 28800314
Journal: Mol Cancer. 2017 Aug 14;16(1):136.
Title: STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4.
Author: Wang, Hui|Huo, Xisong|Yang, Xin-Rong|He, Jia|Cheng, Lijun|Wang, Na|Deng, Xuan|Jin, Haojie|Wang, Ning|Wang, Cun|Zhao, Fangyu|Fang, Jingyuan|Yao, Ming|Fan, Jia|Qin, Wenxin
PMID: 28810927
Journal: Eur Rev Med Pharmacol Sci. 2017 Aug;21(15):3402-3411.
Title: Promotion of LncRNA HOXA11-AS on the proliferation of hepatocellular carcinoma by regulating the expression of LATS1.
Author: Yu, J|Hong, J-F|Kang, J|Liao, L-H|Li, C-D
PMID: 28829501
Journal: Oncogene. 2017 Dec 14;36(50):6895-6905.
Title: Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Author: Feng, G X|Li, J|Yang, Z|Zhang, S Q|Liu, Y X|Zhang, W Y|Ye, L H|Zhang, X D
PMID: 28846110
Journal: Eur J Pharmacol. 2017 Nov 15;815:173-180.
Title: 20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription.
Author: Li, Qi|Li, Bai|Dong, Chengya|Wang, Yajie|Li, Qi
PMID: 28928088
Journal: Am J Cancer Res. 2017 Sep 1;7(9):1874-1883. eCollection 2017.
Title: Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway.
Author: Gao, Shu-Bin|Li, Kang-Li|Qiu, Huan|Zhu, Ling-Yu|Pan, Chang-Bao|Zhao, Yue|Wei, Shu-Hua|Shi, Shu|Jin, Guang-Hui|Xue, Li-Xiang
PMID: 28979810
Journal: Cell Death Dis. 2017 Oct 5;8(10):e3092.
Title: Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression.
Author: Chen, Zhenyao|Chen, Xin|Chen, Ping|Yu, Shanxun|Nie, Fengqi|Lu, Binbin|Zhang, Te|Zhou, Yue|Chen, Qinnan|Wei, Chenchen|Wang, Wei|Wang, Zhaoxia
PMID: 28981099
Journal: Oncotarget. 2017 Jul 26;8(41):70172-70182.
Title: Long non-coding RNA CARLo-5 promotes tumor progression in hepatocellular carcinoma via suppressing miR-200b expression.
Author: Dou, Chunqing|Sun, Liyuan|Jin, Xin|Han, Mingming|Zhang, Bao|Jiang, Xian|Lv, Jinyong|Li, Tao
PMID: 29050269
Journal: Oncol Lett. 2017 Nov;14(5):6109-6116.
Title: Epigenetic analysis of FHL1 tumor suppressor gene in human liver cancer.
Author: Wang, Jun|Huang, Fang|Huang, Jian|Kong, Jindan|Liu, Shenglan|Jin, Jun
PMID: 29113254
Journal: Oncotarget. 2017 Aug 18;8(48):84153-84167.
Title: Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3.
Author: Ma, Zhonghua|Huang, Hesuyuan|Wang, Jirong|Zhou, Yan|Pu, Fuxing|Zhao, Qinghong|Peng, Peng|Hui, Bingqing|Ji, Hao|Wang, Keming
PMID: 29137412
Journal: Mol Med Rep. 2017 Dec;16(6):9494-9502.
Title: MicroRNA137 has a suppressive role in liver cancer via targeting EZH2.
Author: Cui, Shichang|Sun, Yanlei|Liu, Yang|Liu, Chengbiao|Wang, Jinbao|Hao, Guang|Sun, Qidong
PMID: 29152663
Journal: Oncotarget. 2017 Oct 10;8(61):103785-103796.
Title: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/beta-catenin activation.
Author: Li, Xiaopeng|Li, Ming|Chen, JiaLi|Dai, Hua|Wang, Liang|Xiong, Ying|Zhong, Yuanbin|Zhang, Lunli
PMID: 29262600
Journal: Oncotarget. 2017 Nov 27;8(65):109509-109521.
Title: Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5.
Author: Liu, Bin|Li, Jing|Liu, Xiaoling|Zheng, Min|Yang, Ye|Lyu, Qian|Jin, Li
PMID: 29312625
Journal: Histopathology. 2018 Feb;72(3):414-422.
Title: From large to small: the immunohistochemical panel in the diagnosis of early hepatocellular carcinoma.
Author: Vasuri, Francesco|Malvi, Deborah|Bonora, Sonia|Fittipaldi, Silvia|Renzulli, Matteo|Tovoli, Francesco|Golfieri, Rita|Bolondi, Luigi|D'Errico, Antonia
PMID: 28881044
Journal: Gut. 2018 May;67(5):931-944.
Title: Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.
Author: Zhou, Jingying|Liu, Man|Sun, Hanyong|Feng, Yu|Xu, Liangliang|Chan, Anthony W H|Tong, Joanna H|Wong, John|Chong, Charing Ching Ning|Lai, Paul B S|Wang, Hector Kwong-Sang|Tsang, Shun-Wa|Goodwin, Tyler|Liu, Rihe|Huang, Leaf|Chen, Zhiwei|Sung, Joseph Jy|Chow,
PMID: 28939663
Journal: Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G559-G565.
Title: lncRNA MIAT promotes proliferation and invasion of HCC cells via sponging miR-214.
Author: Huang, Xinli|Gao, Yun|Qin, Jianjie|Lu, Sen
PMID: 29097358
Journal: Mol Carcinog. 2018 Mar;57(3):408-418.
Title: LncAPC drives Wnt/beta-catenin activation and liver TIC self-renewal through EZH2 mediated APC transcriptional inhibition.
Author: Fu, Xiaomin|Lin, Jizhen|Qin, Fujun|Yang, Zihe|Ding, Yuechao|Zhang, Yong|Han, Lu|Zhu, Xiaoyan|Zhang, Qinxian
PMID: 29144570
Journal: Biochem Biophys Res Commun. 2018 Jan 22;495(4):2622-2629.
Title: Long noncoding RNA PCAT-1 acts as an oncogene in osteosarcoma by reducing p21 levels.
Author: Huang, Jiang|Deng, Gaorong|Liu, Tianmi|Chen, Wenzhao|Zhou, Yang
PMID: 29291409
Journal: J Exp Clin Cancer Res. 2018 Jan 9;37(1):3.
Title: EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis.
Author: Chen, Shaofei|Pu, Jiarui|Bai, Jie|Yin, Yuping|Wu, Ke|Wang, Jiliang|Shuai, Xiaoming|Gao, Jinbo|Tao, Kaixiong|Wang, Guobin|Li, Hang
PMID: 29316949
Journal: Pharmacol Ther. 2018 Jun;186:138-151.
Title: CCRK is a novel signalling hub exploitable in cancer immunotherapy.
Author: Mok, Myth T|Zhou, Jingying|Tang, Wenshu|Zeng, Xuezhen|Oliver, Antony W|Ward, Simon E|Cheng, Alfred S
PMID: 29360538
Journal: Oncol Lett. 2018 Mar;15(3):2953-2961.
Title: Expression of EZH2 is associated with poor outcome in colorectal cancer.
Author: Chen, Zhuanpeng|Yang, Ping|Li, Wanglin|He, Feng|Wei, Jianchang|Zhang, Tong|Zhong, Junbin|Chen, Huacui|Cao, Jie
PMID: 29435024
Journal: Clin Lab. 2018 Jan 1;64(1):85-91.
Title: Association between EZH2 Genetic Variants and Hepatocellular Carcinoma in a Chinese Han Population.
Author: Li, Siyao|Sun, Shilong|Yu, Shilong|Dong, Zhuo|Jiang, Kuo|Xiang, Linlin|Li, Haiying
PMID: 29479874
Journal: Molecules. 2018 Mar 2;23(3). pii: molecules23030567.
Title: Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.
Author: Ding, Hong|Lu, Wen Chao|Hu, Jun Chi|Liu, Yu-Chih|Zhang, Chen Hua|Lian, Fu Lin|Zhang, Nai Xia|Meng, Fan Wang|Luo, Cheng|Chen, Kai Xian
PMID: 29498708
Journal: Mol Med Rep. 2018 May;17(5):7460.
Title: [Corrigendum] MicroRNA-137 has a suppressive role in liver cancer via targeting EZH2.
Author: Cui, Shichang|Sun, Yanlei|Liu, Yang|Liu, Chengbiao|Wang, Jinbao|Hao, Guang|Sun, Qidong
PMID: 29568886
Journal: J Cell Physiol. 2018 Sep;233(9):6508-6517.
Title: The role of enhancer of zeste homolog 2: From viral epigenetics to the carcinogenesis of hepatocellular carcinoma.
Author: Sanna, Luca|Marchesi, Irene|Melone, Mariarosa A B|Bagella, Luigi
PMID: 29574790
Journal: Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3509-E3518.
Title: Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells.
Author: Bugide, Suresh|Green, Michael R|Wajapeyee, Narendra
PMID: 29581297
Journal: Cancer Lett. 2018 Jul 10;426:98-108.
Title: MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma.
Author: Zhang, Xiang|Zhang, Xiao|Wang, Ting|Wang, Lei|Tan, Zhijun|Wei, Wei|Yan, Bo|Zhao, Jing|Wu, Kaichun|Yang, Angang|Zhang, Rui|Jia, Lintao
PMID: 29653269
Journal: Cell Physiol Biochem. 2018;46(3):1122-1133.
Title: Upregulation of LncDQ is Associated with Poor Prognosis and Promotes Tumor Progression via Epigenetic Regulation of the EMT Pathway in HCC.
Author: Zeng, Bing|Lin, Zewei|Ye, Huilin|Cheng, Di|Zhang, Guangtao|Zhou, Jindu|Huang, Zhifeng|Wang, Meng|Cai, Canfeng|Zeng, Jun|Tang, Chaoming|Liu, Jikui
PMID: 29669339
Journal: Biomed Pharmacother. 2018 Aug;104:137-144.
Title: LncRNA SOX21-AS1 is associated with progression of hepatocellular carcinoma and predicts prognosis through epigenetically silencing p21.
Author: Wei, Congxin|Wang, Hong|Xu, Fei|Liu, Zeng|Jiang, Runde
PMID: 29772433
Journal: Mol Ther Nucleic Acids. 2018 Jun 1;11:23-33.
Title: Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors.
Author: Wang, Hong|Guo, Rui|Du, Zhonghua|Bai, Ling|Li, Lingyu|Cui, Jiuwei|Li, Wei|Hoffman, Andrew R|Hu, Ji-Fan
PMID: 29858058
Journal: Nucleic Acids Res. 2018 Sep 28;46(17):8832-8847.
Title: Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis.
Author: Lee, Ying-Ying|Mok, Myth Ts|Kang, Wei|Yang, Weiqin|Tang, Wenshu|Wu, Feng|Xu, Liangliang|Yan, Mingfei|Yu, Zhuo|Lee, Sau-Dan|Tong, Joanna H M|Cheung, Yue-Sun|Lai, Paul B S|Yu, Dae-Yeul|Wang, Qianben|Wong, Grace L H|Chan, Andrew M|Yip, Kevin Y|To, Ka-Fai|Che
PMID: 29992318
Journal: Cancer Cell Int. 2018 Jul 11;18:98.
Title: Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2.
Author: Guo, Jianping|Hao, Chong|Wang, Congcong|Li, Luo
PMID: 30008615
Journal: Front Physiol. 2018 Jul 27;9:1019.
Title: Dysfunction of Sister Chromatids Separation Promotes Progression of Hepatocellular Carcinoma According to Analysis of Gene Expression Profiling.
Author: Sun, Baozhen|Lin, Guibo|Ji, Degang|Li, Shuo|Chi, Guonan|Jin, Xingyi
PMID: 30100882
Journal: EBioMedicine. 2018 Sep;35:155-166.
Title: Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/beta-catenin signaling.
Author: Song, Haibin|Yu, Zhuo|Sun, Xuehua|Feng, Jun|Yu, Qi|Khan, Hanif|Zhu, Xiaojun|Huang, Lingying|Li, Man|Mok, Myth T S|Cheng, Alfred S L|Gao, Yueqiu|Feng, Hai
PMID: 30150059
Journal: EBioMedicine. 2018 Sep 5. pii: S2352-3964(18)30348-7.
Title: LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation.
Author: Cheng, Di|Deng, Junge|Zhang, Bin|He, Xiaoyu|Meng, Zhe|Li, Guolin|Ye, Huilin|Zheng, Shangyou|Wei, Lusheng|Deng, Xiaogeng|Chen, Rufu|Zhou, Jiajia
PMID: 30195653
Journal: Pathol Res Pract. 2018 Aug 8. pii: S0344-0338(18)30139-0.
Title: MiR-137 suppresses migration and invasion by targeting EZH2-STAT3 signaling in human hepatocellular carcinoma.
Author: Huang, Bin|Huang, Manping|Li, Qin
PMID: 30274685
Journal: Biochem Biophys Res Commun. 2018 Oct 17. pii: S0006-291X(18)32184-3.
Title: HANR promotes hepatocellular carcinoma progression via miR-214/EZH2/TGF-beta axis.
Author: Shi, Yang|Yang, Xiaohua|Xue, Xiaofeng|Sun, Ding|Cai, Peng|Song, Qingwei|Zhang, Bin|Qin, Lei
PMID: 30342849