Primary Site >> Colorectal Cancer
Gene >> EZH2
| 1. | |||||||||||
| Journal: | Mol Cancer Ther. 2003 Jan;2(1):113-21. | ||||||||||
| Title: | Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy. | ||||||||||
| Author: | Kirmizis, Antonis|Bartley, Stephanie M|Farnham, Peggy J | ||||||||||
| PMID: | 12533679 | ||||||||||
| 2. | |||||||||||
| Journal: | Genes Dev. 2004 Jul 1;18(13):1592-605. | ||||||||||
| Title: | Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. | ||||||||||
| Author: | Kirmizis, Antonis|Bartley, Stephanie M|Kuzmichev, Andrei|Margueron, Raphael|Reinberg, Danny|Green, Roland|Farnham, Peggy J | ||||||||||
| PMID: | 15231737 | ||||||||||
| 3. | |||||||||||
| Journal: | Eur J Surg Oncol. 2005 May;31(4):376-80. | ||||||||||
| Title: | Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases. | ||||||||||
| Author: | Mimori, K|Ogawa, K|Okamoto, M|Sudo, T|Inoue, H|Mori, M | ||||||||||
| PMID: | 15837043 | ||||||||||
| 4. | |||||||||||
| Journal: | PLoS Biol. 2008 Dec 2;6(12):2911-27. | ||||||||||
| Title: | PcG proteins, DNA methylation, and gene repression by chromatin looping. | ||||||||||
| Author: | Tiwari, Vijay K|McGarvey, Kelly M|Licchesi, Julien D F|Ohm, Joyce E|Herman, James G|Schubeler, Dirk|Baylin, Stephen B | ||||||||||
| PMID: | 19053175 | ||||||||||
| 5. | |||||||||||
| Journal: | Br J Cancer. 2009 Oct 20;101(8):1282-9. | ||||||||||
| Title: | Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. | ||||||||||
| Author: | Fluge, O|Gravdal, K|Carlsen, E|Vonen, B|Kjellevold, K|Refsum, S|Lilleng, R|Eide, T J|Halvorsen, T B|Tveit, K M|Otte, A P|Akslen, L A|Dahl, O | ||||||||||
| PMID: | 19773751 | ||||||||||
| 6. | |||||||||||
| Journal: | World J Gastroenterol. 2010 May 21;16(19):2421-7. | ||||||||||
| Title: | EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. | ||||||||||
| Author: | Wang, Cheng-Gang|Ye, Ying-Jiang|Yuan, Jing|Liu, Fang-Fang|Zhang, Hui|Wang, Shan | ||||||||||
| PMID: | 20480530 | ||||||||||
| 7. | |||||||||||
| Journal: | Carcinogenesis. 2010 Sep;31(9):1567-75. | ||||||||||
| Title: | The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer. | ||||||||||
| Author: | Kodach, Liudmila L|Jacobs, Rutger J|Heijmans, Jarom|van Noesel, Carel J M|Langers, Alexandra M J|Verspaget, Hein W|Hommes, Daniel W|Offerhaus, G Johan A|van den Brink, Gijs R|Hardwick, James C H | ||||||||||
| PMID: | 20631058 | ||||||||||
| 8. | |||||||||||
| Journal: | PLoS One. 2010 Dec 3;5(12):e14229. | ||||||||||
| Title: | Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome. | ||||||||||
| Author: | Pancione, Massimo|Sabatino, Lina|Fucci, Alessandra|Carafa, Vincenzo|Nebbioso, Angela|Forte, Nicola|Febbraro, Antonio|Parente, Domenico|Ambrosino, Concetta|Normanno, Nicola|Altucci, Lucia|Colantuoni, Vittorio | ||||||||||
| PMID: | 21151932 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Sci. 2011 Jul;102(7):1298-305. | ||||||||||
| Title: | Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. | ||||||||||
| Author: | Takawa, Masashi|Masuda, Ken|Kunizaki, Masaki|Daigo, Yataro|Takagi, Katsunori|Iwai, Yukiko|Cho, Hyun-Soo|Toyokawa, Gouji|Yamane, Yuka|Maejima, Kazuhiro|Field, Helen I|Kobayashi, Takaaki|Akasu, Takayuki|Sugiyama, Masanori|Tsuchiya, Eijyu|Atomi, Yutaka|Ponde | ||||||||||
| PMID: | 21539681 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2011;6(7):e21651. | ||||||||||
| Title: | EZH2 depletion blocks the proliferation of colon cancer cells. | ||||||||||
| Author: | Fussbroich, Bettina|Wagener, Nina|Macher-Goeppinger, Stephan|Benner, Axel|Falth, Maria|Sultmann, Holger|Holzer, Angela|Hoppe-Seyler, Karin|Hoppe-Seyler, Felix | ||||||||||
| PMID: | 21765901 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2011 Oct 15;71(20):6320-6. | ||||||||||
| Title: | Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. | ||||||||||
| Author: | Kogo, Ryunosuke|Shimamura, Teppei|Mimori, Koshi|Kawahara, Kohichi|Imoto, Seiya|Sudo, Tomoya|Tanaka, Fumiaki|Shibata, Kohei|Suzuki, Akira|Komune, Shizuo|Miyano, Satoru|Mori, Masaki | ||||||||||
| PMID: | 21862635 | ||||||||||
| 12. | |||||||||||
| Journal: | Ann Oncol. 2012 May;23(5):1207-13. | ||||||||||
| Title: | An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. | ||||||||||
| Author: | Crea, F|Fornaro, L|Paolicchi, E|Masi, G|Frumento, P|Loupakis, F|Salvatore, L|Cremolini, C|Schirripa, M|Graziano, F|Ronzoni, M|Ricci, V|Farrar, W L|Falcone, A|Danesi, R | ||||||||||
| PMID: | 21926398 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biol Chem. 2012 Jan 20;287(4):2798-809. | ||||||||||
| Title: | TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer. | ||||||||||
| Author: | Lee, Chun-Chung|Chen, Wei-Shone|Chen, Chia-Chi|Chen, Li-Li|Lin, Yi-Shing|Fan, Chi-Shuan|Huang, Tze-Sing | ||||||||||
| PMID: | 22130667 | ||||||||||
| 14. | |||||||||||
| Journal: | Ann Oncol. 2012 May;23(5):1370-1. | ||||||||||
| Title: | EZH2 polymorphism and benefit from bevacizumab in colorectal cancer: another piece to the puzzle. | ||||||||||
| Author: | Fornaro, L|Crea, F|Masi, G|Paolicchi, E|Loupakis, F|Graziano, F|Salvatore, L|Ronzoni, M|Ricci, V|Cremolini, C|Schirripa, M|Danesi, R|Falcone, A | ||||||||||
| PMID: | 22383679 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2012;7(9):e44206. | ||||||||||
| Title: | MiR-214 targets beta-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. | ||||||||||
| Author: | Xia, Hongping|Ooi, London Lucien P J|Hui, Kam M | ||||||||||
| PMID: | 22962603 | ||||||||||
| 16. | |||||||||||
| Journal: | J Cell Physiol. 2013 Apr;228(4):764-72. | ||||||||||
| Title: | Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells. | ||||||||||
| Author: | Benoit, Yannick D|Laursen, Kristian B|Witherspoon, Mavee S|Lipkin, Steven M|Gudas, Lorraine J | ||||||||||
| PMID: | 23001792 | ||||||||||
| 17. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2013 Feb;45(2):243-54. | ||||||||||
| Title: | EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells. | ||||||||||
| Author: | Ferraro, Angelo|Mourtzoukou, Despoina|Kosmidou, Vivian|Avlonitis, Spiros|Kontogeorgos, George|Zografos, George|Pintzas, Alexander | ||||||||||
| PMID: | 23116973 | ||||||||||
| 18. | |||||||||||
| Journal: | J Pathol. 2013 Jul;230(3):277-90. | ||||||||||
| Title: | Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. | ||||||||||
| Author: | Lin, Yan-Wei|Ren, Lin-Lin|Xiong, Hua|Du, Wan|Yu, Ya-Nan|Sun, Tian-Tian|Weng, Yu-Rong|Wang, Zhen-Hua|Wang, Ji-Lin|Wang, Ying-Chao|Cui, Yun|Sun, Dan-Feng|Han, Ze-Guang|Shen, Nan|Zou, Weiping|Xu, Jie|Chen, Hao-Yan|Cao, Weibiao|Hong, Jie|Fang, Jing-Yuan | ||||||||||
| PMID: | 23424038 | ||||||||||
| 19. | |||||||||||
| Journal: | Eur J Surg Oncol. 2013 Jun;39(6):655-61. | ||||||||||
| Title: | Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancer. | ||||||||||
| Author: | Tamagawa, H|Oshima, T|Numata, M|Yamamoto, N|Shiozawa, M|Morinaga, S|Nakamura, Y|Yoshihara, M|Sakuma, Y|Kameda, Y|Akaike, M|Yukawa, N|Rino, Y|Masuda, M|Miyagi, Y | ||||||||||
| PMID: | 23523318 | ||||||||||
| 20. | |||||||||||
| Journal: | Exp Cell Res. 2013 Jun 10;319(10):1463-70. | ||||||||||
| Title: | Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells. | ||||||||||
| Author: | Benoit, Yannick D|Witherspoon, Mavee S|Laursen, Kristian B|Guezguez, Amel|Beausejour, Marco|Beaulieu, Jean-Francois|Lipkin, Steven M|Gudas, Lorraine J | ||||||||||
| PMID: | 23588203 | ||||||||||
| 21. | |||||||||||
| Journal: | Onco Targets Ther. 2013 Apr 4;6:321-4. | ||||||||||
| Title: | Update of research on the role of EZH2 in cancer progression. | ||||||||||
| Author: | Shen, Liang|Cui, Jing|Liang, Shumei|Pang, Yingxin|Liu, Peishu | ||||||||||
| PMID: | 23589697 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Cell. 2013 Oct 24;52(2):193-205. | ||||||||||
| Title: | PAF and EZH2 induce Wnt/beta-catenin signaling hyperactivation. | ||||||||||
| Author: | Jung, Hae-Yun|Jun, Sohee|Lee, Moonsup|Kim, Han-Cheon|Wang, Xin|Ji, Hong|McCrea, Pierre D|Park, Jae-Il | ||||||||||
| PMID: | 24055345 | ||||||||||
| 23. | |||||||||||
| Journal: | Mol Cell. 2013 Oct 24;52(2):157-8. | ||||||||||
| Title: | PAF makes it EZ(H2) for beta-catenin transactivation. | ||||||||||
| Author: | Zhang, Xinjun|He, Xi | ||||||||||
| PMID: | 24210173 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2014 Dec 1;135(11):2528-36. | ||||||||||
| Title: | Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. | ||||||||||
| Author: | Ishikawa, S|Hayashi, H|Kinoshita, K|Abe, M|Kuroki, H|Tokunaga, R|Tomiyasu, S|Tanaka, H|Sugita, H|Arita, T|Yagi, Y|Watanabe, M|Hirota, M|Baba, H | ||||||||||
| PMID: | 24346863 | ||||||||||
| 25. | |||||||||||
| Journal: | Med Oncol. 2014 Mar;31(3):874. | ||||||||||
| Title: | Association between EZH2 polymorphisms and colorectal cancer risk in Han Chinese population. | ||||||||||
| Author: | Wang, Jian|Ma, Zhen-Bin|Li, Kun|Guo, Guang-Hong | ||||||||||
| PMID: | 24488618 | ||||||||||
| 26. | |||||||||||
| Journal: | Carcinogenesis. 2014 Jun;35(6):1389-98. | ||||||||||
| Title: | Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, beta-catenin and EZH2. | ||||||||||
| Author: | Weng, Yu-Rong|Yu, Ya-Nan|Ren, Lin-Lin|Cui, Yun|Lu, You-Yong|Chen, Hao-Yan|Ma, Xiong|Qin, Wen-Xin|Cao, Weibiao|Hong, Jie|Fang, Jing-Yuan | ||||||||||
| PMID: | 24608043 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Death Dis. 2014 Jul 17;5:e1324. | ||||||||||
| Title: | Integrative epigenome analysis identifies a Polycomb-targeted differentiation program as a tumor-suppressor event epigenetically inactivated in colorectal cancer. | ||||||||||
| Author: | Tan, J|Yang, X|Jiang, X|Zhou, J|Li, Z|Lee, P L|Li, B|Robson, P|Yu, Q | ||||||||||
| PMID: | 25032847 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Med. 2014 Dec;3(6):1544-52. | ||||||||||
| Title: | Low expression levels of microRNA-124-5p correlated with poor prognosis in colorectal cancer via targeting of SMC4. | ||||||||||
| Author: | Jinushi, Takafumi|Shibayama, Yoshihiko|Kinoshita, Ichiro|Oizumi, Satoshi|Jinushi, Masahisa|Aota, Tadahiro|Takahashi, Toshiyuki|Horita, Shoichi|Dosaka-Akita, Hirotoshi|Iseki, Ken | ||||||||||
| PMID: | 25081869 | ||||||||||
| 29. | |||||||||||
| Journal: | Radiat Oncol. 2014 Aug 27;9:188. | ||||||||||
| Title: | The prognostic role of EZH2 expression in rectal cancer patients treated with neoadjuvant chemoradiotherapy. | ||||||||||
| Author: | Meng, Xiangjiao|Huang, Zhaoqin|Wang, Renben|Jiao, Yuhong|Li, Huijuan|Xu, Xiaoqing|Feng, Rui|Zhu, Kunli|Jiang, Shumei|Yan, Hongjiang|Yu, Jinming | ||||||||||
| PMID: | 25159232 | ||||||||||
| 30. | |||||||||||
| Journal: | PLoS One. 2014 Sep 17;9(9):e107905. | ||||||||||
| Title: | Epigenetic mechanisms underlying the dynamic expression of cancer-testis genes, PAGE2, -2B and SPANX-B, during mesenchymal-to-epithelial transition. | ||||||||||
| Author: | Yilmaz-Ozcan, Sinem|Sade, Asli|Kucukkaraduman, Baris|Kaygusuz, Yasemin|Senses, Kerem Mert|Banerjee, Sreeparna|Gure, Ali Osmay | ||||||||||
| PMID: | 25229454 | ||||||||||
| 31. | |||||||||||
| Journal: | PLoS One. 2014 Sep 22;9(9):e108265. | ||||||||||
| Title: | Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer. | ||||||||||
| Author: | Benard, Anne|Goossens-Beumer, Ines J|van Hoesel, Anneke Q|Horati, Hamed|Putter, Hein|Zeestraten, Eliane C M|van de Velde, Cornelis J H|Kuppen, Peter J K | ||||||||||
| PMID: | 25243792 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncotarget. 2014 Sep 30;5(18):8123-35. | ||||||||||
| Title: | Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer. | ||||||||||
| Author: | Gaedcke, Jochen|Leha, Andreas|Claus, Rainer|Weichenhan, Dieter|Jung, Klaus|Kitz, Julia|Grade, Marian|Wolff, Hendrik A|Jo, Peter|Doyen, Jerome|Gerard, Jean-Pierre|Johnsen, Steven A|Plass, Christoph|Beissbarth, Tim|Ghadimi, Michael | ||||||||||
| PMID: | 25261372 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Biol Ther. 2014;15(12):1677-87. | ||||||||||
| Title: | EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells. | ||||||||||
| Author: | Katona, Bryson W|Liu, Yuanyuan|Ma, Anqi|Jin, Jian|Hua, Xianxin | ||||||||||
| PMID: | 25535899 | ||||||||||
| 34. | |||||||||||
| Journal: | PLoS One. 2014 Dec 26;9(12):e115684. | ||||||||||
| Title: | JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines. | ||||||||||
| Author: | Tange, Shoichiro|Oktyabri, Dulamsuren|Terashima, Minoru|Ishimura, Akihiko|Suzuki, Takeshi | ||||||||||
| PMID: | 25542019 | ||||||||||
| 35. | |||||||||||
| Journal: | PLoS One. 2014 Dec 30;9(12):e115276. | ||||||||||
| Title: | EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene. | ||||||||||
| Author: | Ferraro, Angelo|Boni, Themis|Pintzas, Alexander | ||||||||||
| PMID: | 25549357 | ||||||||||
| 36. | |||||||||||
| Journal: | Exp Biol Med (Maywood). 2015 Apr;240(4):458-66. | ||||||||||
| Title: | Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro. | ||||||||||
| Author: | He, Song-Bing|Zhou, Hao|Zhou, Jian|Zhou, Guo-Qiang|Han, Tuo|Wan, Dai-Wei|Gu, Wen|Gao, Lin|Zhang, Yi|Xue, Xiao-Feng|Zhang, Li-Feng|Fei, Min|Hu, Shui-Qing|Yang, Xiao-Dong|Zhu, Xin-Guo|Wang, Liang|Li, De-Chun | ||||||||||
| PMID: | 25005166 | ||||||||||
| 37. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2015 Apr;141(4):661-9. | ||||||||||
| Title: | Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer. | ||||||||||
| Author: | Liu, Yan-Long|Gao, Xu|Jiang, Yang|Zhang, Gan|Sun, Zi-Cheng|Cui, Bin-Bin|Yang, Yan-Mei | ||||||||||
| PMID: | 25326896 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncogene. 2015 Aug 20;34(34):4519-30. | ||||||||||
| Title: | Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2. | ||||||||||
| Author: | Roy, B C|Subramaniam, D|Ahmed, I|Jala, V R|Hester, C M|Greiner, K A|Haribabu, B|Anant, S|Umar, S | ||||||||||
| PMID: | 25486432 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Lett. 2015 Apr 10;359(2):198-205. | ||||||||||
| Title: | DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression. | ||||||||||
| Author: | Ning, Xianghong|Shi, Zhendong|Liu, Xi|Zhang, Anling|Han, Lei|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu | ||||||||||
| PMID: | 25595591 | ||||||||||
| 40. | |||||||||||
| Journal: | Cell Death Dis. 2015 Jan 22;6:e1614. | ||||||||||
| Title: | Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer. | ||||||||||
| Author: | Vishnubalaji, R|Hamam, R|Abdulla, M-H|Mohammed, M A V|Kassem, M|Al-Obeed, O|Aldahmash, A|Alajez, N M | ||||||||||
| PMID: | 25611389 | ||||||||||
| 41. | |||||||||||
| Journal: | Carcinogenesis. 2015 Mar;36(3):355-67. | ||||||||||
| Title: | Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. | ||||||||||
| Author: | Toden, Shusuke|Okugawa, Yoshinaga|Jascur, Thomas|Wodarz, Dominik|Komarova, Natalia L|Buhrmann, Constanze|Shakibaei, Mehdi|Boland, C Richard|Goel, Ajay | ||||||||||
| PMID: | 25653233 | ||||||||||
| 42. | |||||||||||
| Journal: | Mol Med Rep. 2015 Jul;12(1):728-36. | ||||||||||
| Title: | Regulation of the expression of claudin 23 by the enhancer of zeste 2 polycomb group protein in colorectal cancer. | ||||||||||
| Author: | Maryan, Natalia|Statkiewicz, Malgorzata|Mikula, Michal|Goryca, Krzysztof|Paziewska, Agnieszka|Strzalkowska, Adriana|Dabrowska, Michalina|Bujko, Mateusz|Ostrowski, Jerzy | ||||||||||
| PMID: | 25695204 | ||||||||||
| 43. | |||||||||||
| Journal: | Exp Biol Med (Maywood). 2015 Apr;240(4):546-55. | ||||||||||
| Title: | Inhibition of EZH2 expression is associated with the proliferation, apoptosis and migration of SW620 colorectal cancer cells in vitro. | ||||||||||
| Author: | Song-Bing, He|Hao, Zhou|Jian, Zhou|Guo-Qiang, Zhou|Tuo, Han|Dai-Wei, Wan|Wen, Gu|Lin, Gao|Yi, Zhang|Xiao-Feng, Xue|Li-Feng, Zhang|Min, Fei|Shui-Qing, Hi|Xiao-Dong, Yang|Xin-Guo, Zhu|Liang, Wang|De-Chun, Li | ||||||||||
| PMID: | 25724194 | ||||||||||
| 44. | |||||||||||
| Journal: | J Pathol. 2015 Dec;237(4):508-19. | ||||||||||
| Title: | Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis. | ||||||||||
| Author: | McCleland, Mark L|Soukup, Tim M|Liu, Scot D|Esensten, Jonathan H|de Sousa e Melo, Felipe|Yaylaoglu, Murat|Warming, Soren|Roose-Girma, Merone|Firestein, Ron | ||||||||||
| PMID: | 26235356 | ||||||||||
| 45. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2015 Dec;54(12):776-87. | ||||||||||
| Title: | Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer. | ||||||||||
| Author: | Joensuu, Emmi I|Nieminen, Taina T|Lotsari, Johanna E|Pavicic, Walter|Abdel-Rahman, Wael M|Peltomaki, Paivi | ||||||||||
| PMID: | 26305882 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 29;6(29):27427-39. | ||||||||||
| Title: | The positive feedback between Snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer. | ||||||||||
| Author: | Wang, Jianmei|Zhu, Xiaohui|Hu, Jinlong|He, Guoyang|Li, Xiaomei|Wu, Pingxiang|Ren, Xiaoli|Wang, Feifei|Liao, Wenting|Liang, Li|Ding, Yanqing | ||||||||||
| PMID: | 26336990 | ||||||||||
| 47. | |||||||||||
| Journal: | Exp Cell Res. 2015 Nov 1;338(2):214-21. | ||||||||||
| Title: | Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells. | ||||||||||
| Author: | Wang, Haibo|Ge, Shengfang|Qian, Guanxiang|Li, Wei|Cui, Jiuwei|Wang, Guanjun|Hoffman, Andrew R|Hu, Ji-Fan | ||||||||||
| PMID: | 26407907 | ||||||||||
| 48. | |||||||||||
| Journal: | Oncotarget. 2015 Oct 20;6(32):32586-601. | ||||||||||
| Title: | MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2. | ||||||||||
| Author: | Zhang, Yi|Lin, Changwei|Liao, Guoqing|Liu, Sheng|Ding, Jie|Tang, Fang|Wang, Zhenran|Liang, Xingsi|Li, Bo|Wei, Yangchao|Huang, Qi|Li, Xuan|Tang, Bo | ||||||||||
| PMID: | 26452129 | ||||||||||
| 49. | |||||||||||
| Journal: | Oncotarget. 2015 Nov 10;6(35):37257-68. | ||||||||||
| Title: | Wnt2 complements Wnt/beta-catenin signaling in colorectal cancer. | ||||||||||
| Author: | Jung, Youn-Sang|Jun, Sohee|Lee, Sun Hye|Sharma, Amrish|Park, Jae-Il | ||||||||||
| PMID: | 26484565 | ||||||||||
| 50. | |||||||||||
| Journal: | BMC Cancer. 2015 Nov 9;15:874. | ||||||||||
| Title: | Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer. | ||||||||||
| Author: | Fornaro, Lorenzo|Faviana, Pinuccia|De Gregorio, Veronica|Vivaldi, Caterina|Paolicchi, Elisa|Masi, Gianluca|Loupakis, Fotios|Sensi, Elisa|Lupi, Cristiana|Fontanini, Gabriella|Wang, Yuzhuo|Danesi, Romano|Falcone, Alfredo|Crea, Francesco | ||||||||||
| PMID: | 26553291 | ||||||||||
| 51. | |||||||||||
| Journal: | Acta Pharm Sin B. 2015 May;5(3):188-93. | ||||||||||
| Title: | DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis. | ||||||||||
| Author: | Sha, Mingquan|Mao, Genxiang|Wang, Guofu|Chen, Yufeng|Wu, Xiaojian|Wang, Zhen | ||||||||||
| PMID: | 26579445 | ||||||||||
| 52. | |||||||||||
| Journal: | Int J Clin Exp Med. 2015 Sep 15;8(9):16043-9. eCollection 2015. | ||||||||||
| Title: | Prognostic significance of EZH2 expression in patients with digestive cancers: a meta-analysis. | ||||||||||
| Author: | Wang, Wei|Wang, Feng|Zong, Guangquan|Liu, Renmin|Zhang, Yufei|Luan, Yang|Xu, Lin|Xuan, Ji | ||||||||||
| PMID: | 26629110 | ||||||||||
| 53. | |||||||||||
| Journal: | Autophagy. 2015;11(12):2309-22. | ||||||||||
| Title: | Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway. | ||||||||||
| Author: | Wei, Fu-Zheng|Cao, Ziyang|Wang, Xi|Wang, Hui|Cai, Mu-Yan|Li, Tingting|Hattori, Naoko|Wang, Donglai|Du, Yipeng|Song, Boyan|Cao, Lin-Lin|Shen, Changchun|Wang, Lina|Wang, Haiying|Yang, Yang|Xie, Dan|Wang, Fan|Ushijima, Toshikazu|Zhao, Ying|Zhu, Wei-Guo | ||||||||||
| PMID: | 26735435 | ||||||||||
| 54. | |||||||||||
| Journal: | Cancer Res. 2016 Jan 15;76(2):275-82. | ||||||||||
| Title: | PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. | ||||||||||
| Author: | Nagarsheth, Nisha|Peng, Dongjun|Kryczek, Ilona|Wu, Ke|Li, Wei|Zhao, Ende|Zhao, Lili|Wei, Shuang|Frankel, Timothy|Vatan, Linda|Szeliga, Wojciech|Dou, Yali|Owens, Scott|Marquez, Victor|Tao, Kaixiong|Huang, Emina|Wang, Guobin|Zou, Weiping | ||||||||||
| PMID: | 26567139 | ||||||||||
| 55. | |||||||||||
| Journal: | Carcinogenesis. 2016 Apr;37(4):385-96. | ||||||||||
| Title: | An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis. | ||||||||||
| Author: | Ahmed, Ishfaq|Roy, Badal C|Subramaniam, Dharmalingam|Ganie, Showkat Ahmad|Kwatra, Deep|Dixon, Dan|Anant, Shrikant|Zargar, Mohammad Afzal|Umar, Shahid | ||||||||||
| PMID: | 26785732 | ||||||||||
| 56. | |||||||||||
| Journal: | J Cell Mol Med. 2016 May;20(5):836-41. | ||||||||||
| Title: | Prognostic significance of EZH2 expression in patients with oesophageal cancer: a meta-analysis. | ||||||||||
| Author: | Wang, Yawei|Gao, Fang|Zhao, Meng|Li, Bing|Xing, Dan|Wang, Jie|Yang, Yang | ||||||||||
| PMID: | 26859127 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 15;7(11):12704-17. | ||||||||||
| Title: | The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway. | ||||||||||
| Author: | Kurihara, Hiroyoshi|Maruyama, Reo|Ishiguro, Kazuya|Kanno, Shinichi|Yamamoto, Itaru|Ishigami, Keisuke|Mitsuhashi, Kei|Igarashi, Hisayoshi|Ito, Miki|Tanuma, Tokuma|Sukawa, Yasutaka|Okita, Kenji|Hasegawa, Tadashi|Imai, Kohzoh|Yamamoto, Hiroyuki|Shinomura, Ya | ||||||||||
| PMID: | 26871294 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 29;7(13):16158-71. | ||||||||||
| Title: | Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer. | ||||||||||
| Author: | Toden, Shusuke|Tran, Hanh-My|Tovar-Camargo, Oscar A|Okugawa, Yoshinaga|Goel, Ajay | ||||||||||
| PMID: | 26930714 | ||||||||||
| 59. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 5;7(27):41540-41558. | ||||||||||
| Title: | EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/beta-catenin signaling. | ||||||||||
| Author: | Chen, Jian-Fang|Luo, Xi|Xiang, Li-Sha|Li, Hong-Tao|Zha, Lin|Li, Ni|He, Jian-Ming|Xie, Gan-Feng|Xie, Xiong|Liang, Hou-Jie | ||||||||||
| PMID: | 27172794 | ||||||||||
| 60. | |||||||||||
| Journal: | Gene. 2016 Oct 30;592(1):172-178. | ||||||||||
| Title: | Long noncoding RNA HULC promotes colorectal carcinoma progression through epigenetically repressing NKD2 expression. | ||||||||||
| Author: | Yang, Xiao-Jun|Huang, Chao-Qun|Peng, Chun-Wei|Hou, Jin-Xuan|Liu, Jiu-Yang | ||||||||||
| PMID: | 27496341 | ||||||||||
| 61. | |||||||||||
| Journal: | Oncotarget. 2016 Oct 25;7(43):69816-69828. | ||||||||||
| Title: | Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition. | ||||||||||
| Author: | Koppens, Martijn A J|Bounova, Gergana|Cornelissen-Steijger, Paulien|de Vries, Nienke|Sansom, Owen J|Wessels, Lodewyk F A|van Lohuizen, Maarten | ||||||||||
| PMID: | 27634879 | ||||||||||
| 62. | |||||||||||
| Journal: | Am J Cancer Res. 2016 Aug 1;6(8):1661-80. eCollection 2016. | ||||||||||
| Title: | EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. | ||||||||||
| Author: | Hsieh, Yao-Yu|Lo, Hsiang-Ling|Yang, Pei-Ming | ||||||||||
| PMID: | 27648357 | ||||||||||
| 63. | |||||||||||
| Journal: | Cell Rep. 2016 Sep 20;16(12):3297-3310. | ||||||||||
| Title: | Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKClambda/iota. | ||||||||||
| Author: | Nakanishi, Yuki|Reina-Campos, Miguel|Nakanishi, Naoko|Llado, Victoria|Elmen, Lisa|Peterson, Scott|Campos, Alex|De, Surya K|Leitges, Michael|Ikeuchi, Hiroki|Pellecchia, Maurizio|Blumberg, Richard S|Diaz-Meco, Maria T|Moscat, Jorge | ||||||||||
| PMID: | 27653691 | ||||||||||
| 64. | |||||||||||
| Journal: | Genes (Basel). 2016 Oct 3;7(10). pii: genes7100083. | ||||||||||
| Title: | Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells. | ||||||||||
| Author: | Yao, Yizhou|Hu, Hao|Yang, Yong|Zhou, Guoqiang|Shang, Zengfu|Yang, Xiaodong|Sun, Kang|Zhan, Shenghua|Yu, Zhengyuan|Li, Peiyao|Pan, Guofeng|Sun, Liang|Zhu, Xinguo|He, Songbing | ||||||||||
| PMID: | 27706111 | ||||||||||
| 65. | |||||||||||
| Journal: | Genet Mol Res. 2016 Sep 30;15(3). pii: gmr007_retraction. | ||||||||||
| Title: | RETRACTION of articles with plagiarism in common with other publications. | ||||||||||
| Author: | |||||||||||
| PMID: | 27706792 | ||||||||||
| 66. | |||||||||||
| Journal: | Cell Death Dis. 2016 Nov 24;7(11):e2486. | ||||||||||
| Title: | EZH2 mediates lidamycin-induced cellular senescence through regulating p21 expression in human colon cancer cells. | ||||||||||
| Author: | Sha, Ming-Quan|Zhao, Xiao-Li|Li, Liang|Li, Li-Hui|Li, Yi|Dong, Tian-Geng|Niu, Wei-Xin|Jia, Li-Jun|Shao, Rong-Guang|Zhen, Yong-Su|Wang, Zhen | ||||||||||
| PMID: | 27882937 | ||||||||||
| 67. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):38227-38238. | ||||||||||
| Title: | Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. | ||||||||||
| Author: | Nie, Fengqi|Yu, Xiang|Huang, Mingde|Wang, Yunfei|Xie, Min|Ma, Hongwei|Wang, Zhaoxia|De, Wei|Sun, Ming | ||||||||||
| PMID: | 27246976 | ||||||||||
| 68. | |||||||||||
| Journal: | Cancer Biomark. 2017;18(1):95-104. | ||||||||||
| Title: | LncRNA-ANCR down-regulation suppresses invasion and migration of colorectal cancer cells by regulating EZH2 expression. | ||||||||||
| Author: | Yang, Zhao-Yang|Yang, Fang|Zhang, Ying-Li|Liu, Bao|Wang, Meng|Hong, Xuan|Yu, Yan|Zhou, Yao-Hui|Zeng, Hai | ||||||||||
| PMID: | 27983539 | ||||||||||
| 69. | |||||||||||
| Journal: | Mol Med Rep. 2017 Feb;15(2):957-962. | ||||||||||
| Title: | Methyl jasmonate induces the apoptosis of human colorectal cancer cells via downregulation of EZH2 expression by microRNA101. | ||||||||||
| Author: | Peng, Zheng|Zhang, Yong | ||||||||||
| PMID: | 28000868 | ||||||||||
| 70. | |||||||||||
| Journal: | Mol Cancer Ther. 2017 Apr;16(4):739-751. | ||||||||||
| Title: | MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2. | ||||||||||
| Author: | Li, Peilong|Zhang, Xin|Wang, Haiyan|Wang, Lili|Liu, Tong|Du, Lutao|Yang, Yongmei|Wang, Chuanxin | ||||||||||
| PMID: | 28069878 | ||||||||||
| 71. | |||||||||||
| Journal: | Oncogenesis. 2017 Jan 23;6(1):e288. | ||||||||||
| Title: | Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. | ||||||||||
| Author: | Ding, J|Xie, M|Lian, Y|Zhu, Y|Peng, P|Wang, J|Wang, L|Wang, K | ||||||||||
| PMID: | 28112720 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 14;8(11):17810-17818. | ||||||||||
| Title: | EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics. | ||||||||||
| Author: | Yamamoto, Itaru|Nosho, Katsuhiko|Kanno, Shinichi|Igarashi, Hisayoshi|Kurihara, Hiroyoshi|Ishigami, Keisuke|Ishiguro, Kazuya|Mitsuhashi, Kei|Maruyama, Reo|Koide, Hideyuki|Okuda, Hiroyuki|Hasegawa, Tadashi|Sukawa, Yasutaka|Okita, Kenji|Takemasa, Ichiro|Yama | ||||||||||
| PMID: | 28147317 | ||||||||||
| 73. | |||||||||||
| Journal: | Anal Chem. 2017 Mar 7;89(5):2773-2781. | ||||||||||
| Title: | Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis To Evaluate Epigenetic Drugs. | ||||||||||
| Author: | Feist, Peter E|Sidoli, Simone|Liu, Xin|Schroll, Monica M|Rahmy, Sharif|Fujiwara, Rina|Garcia, Benjamin A|Hummon, Amanda B | ||||||||||
| PMID: | 28194967 | ||||||||||
| 74. | |||||||||||
| Journal: | Cell Death Dis. 2017 Mar 9;8(3):e2665. | ||||||||||
| Title: | Long noncoding RNA BLACAT1 indicates a poor prognosis of colorectal cancer and affects cell proliferation by epigenetically silencing of p15. | ||||||||||
| Author: | Su, Jun|Zhang, Erbao|Han, Liang|Yin, Dandan|Liu, Zhili|He, Xuezhi|Zhang, Yuhong|Lin, Feng|Lin, Qingfeng|Mao, Peiyao|Mao, Weidong|Shen, Dong | ||||||||||
| PMID: | 28277544 | ||||||||||
| 75. | |||||||||||
| Journal: | Therap Adv Gastroenterol. 2017 Jan;10(1):114-131. | ||||||||||
| Title: | Targeting histone methylation for colorectal cancer. | ||||||||||
| Author: | Huang, Tao|Lin, Chengyuan|Zhong, Linda L D|Zhao, Ling|Zhang, Ge|Lu, Aiping|Wu, Jiang|Bian, Zhaoxiang | ||||||||||
| PMID: | 28286564 | ||||||||||
| 76. | |||||||||||
| Journal: | Tumour Biol. 2017 Apr;39(4):1010428317699122. | ||||||||||
| Title: | The expression pattern of long non-coding RNA PVT1 in tumor tissues and in extracellular vesicles of colorectal cancer correlates with cancer progression. | ||||||||||
| Author: | Guo, Kai|Yao, Jie|Yu, Qiang|Li, Zijian|Huang, Hu|Cheng, Jianguo|Wang, Zhigang|Zhu, Yunfeng | ||||||||||
| PMID: | 28381186 | ||||||||||
| 77. | |||||||||||
| Journal: | Biomed Pharmacother. 2017 Jul;91:1160-1166. | ||||||||||
| Title: | Upregulation of CCAT2 promotes cell proliferation by repressing the P15 in breast cancer. | ||||||||||
| Author: | Deng, Xin|Zhao, Yi|Wu, Xin|Song, Guoqing | ||||||||||
| PMID: | 28531944 | ||||||||||
| 78. | |||||||||||
| Journal: | Evid Based Complement Alternat Med. 2017;2017:8753815. | ||||||||||
| Title: | The Significant Pathways and Genes Underlying the Colon Cancer Treatment by the Traditional Chinese Medicine PHY906. | ||||||||||
| Author: | Su, Ziyuan|Zhou, Changyu|Qin, Shaoyou|Jia, Erna|Wu, Zhenting | ||||||||||
| PMID: | 28588641 | ||||||||||
| 79. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. | ||||||||||
| Title: | The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K | ||||||||||
| PMID: | 28675510 | ||||||||||
| 80. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2017 Nov;143(11):2211-2219. | ||||||||||
| Title: | EZH2 is involved in silencing of WNT5A during epithelial-mesenchymal transition of colon cancer cell line. | ||||||||||
| Author: | Tao, Jianxin|Shi, Liping|Huang, Longchang|Shi, Haoze|Chen, Hang|Wang, Yixin|Wang, Tong | ||||||||||
| PMID: | 28748258 | ||||||||||
| 81. | |||||||||||
| Journal: | Cell Death Dis. 2017 Aug 10;8(8):e2997. | ||||||||||
| Title: | Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression. | ||||||||||
| Author: | Ding, Jie|Li, Juan|Wang, HaiYan|Tian, Yun|Xie, Min|He, XueZhi|Ji, Hao|Ma, Zhonghua|Hui, Bingqing|Wang, Keming|Ji, Guozhong | ||||||||||
| PMID: | 28796262 | ||||||||||
| 82. | |||||||||||
| Journal: | Cancer Res. 2017 Oct 15;77(20):5464-5478. | ||||||||||
| Title: | STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. | ||||||||||
| Author: | Jin, Lin|Vu, Trung|Yuan, Guandou|Datta, Pran K | ||||||||||
| PMID: | 28827371 | ||||||||||
| 83. | |||||||||||
| Journal: | Mol Ther Nucleic Acids. 2017 Sep 15;8:356-369. | ||||||||||
| Title: | |||||||||||