Primary Site >> Colorectal Cancer
Gene >> EREG
| 1. | |||||||||||
| Journal: | Cancer Res. 2000 Dec 15;60(24):6886-9. | ||||||||||
| Title: | Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells. | ||||||||||
| Author: | Baba, I|Shirasawa, S|Iwamoto, R|Okumura, K|Tsunoda, T|Nishioka, M|Fukuyama, K|Yamamoto, K|Mekada, E|Sasazuki, T | ||||||||||
| PMID: | 11156386 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Mol Med. 2006 Jun;17(6):1163-6. | ||||||||||
| Title: | Canonical WNT signaling pathway and human AREG. | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 16685431 | ||||||||||
| 3. | |||||||||||
| Journal: | J Clin Oncol. 2009 Oct 20;27(30):5068-74. | ||||||||||
| Title: | Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab. | ||||||||||
| Author: | Jacobs, Bart|De Roock, Wendy|Piessevaux, Hubert|Van Oirbeek, Robin|Biesmans, Bart|De Schutter, Jef|Fieuws, Steffen|Vandesompele, Jo|Peeters, Marc|Van Laethem, Jean-Luc|Humblet, Yves|Penault-Llorca, Frederique|De Hertogh, Gert|Laurent-Puig, Pierre|Van Cuts | ||||||||||
| PMID: | 19738126 | ||||||||||
| 4. | |||||||||||
| Journal: | Eur J Cancer. 2010 Jul;46(11):2119-26. | ||||||||||
| Title: | Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes. | ||||||||||
| Author: | Watanabe, Toshiaki|Kobunai, Takashi|Yamamoto, Yoko|Kanazawa, Takamitsu|Konishi, Tsuyoshi|Tanaka, Toshiaki|Matsuda, Keiji|Ishihara, Soichiro|Nozawa, Keijiro|Eshima, Kiyoshi|Muto, Tetsuichiro|Nagawa, Hirokazu | ||||||||||
| PMID: | 20570135 | ||||||||||
| 5. | |||||||||||
| Journal: | Onkologie. 2010;33(7):353-8. | ||||||||||
| Title: | Amphiregulin and epiregulin expression in colorectal carcinoma and the correlation with clinicopathological characteristics. | ||||||||||
| Author: | Li, Xiao-Dong|Miao, Su-Yu|Wang, Guo-Liang|Yang, Li|Shu, Yong-Qian|Yin, Yong-Mei | ||||||||||
| PMID: | 20631481 | ||||||||||
| 6. | |||||||||||
| Journal: | PLoS One. 2011 Jan 20;6(1):e15980. | ||||||||||
| Title: | Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients. | ||||||||||
| Author: | Saridaki, Zacharenia|Tzardi, Maria|Papadaki, Chara|Sfakianaki, Maria|Pega, Fraga|Kalikaki, Aristea|Tsakalaki, Eleftheria|Trypaki, Maria|Messaritakis, Ippokratis|Stathopoulos, Efstathios|Mavroudis, Dimitris|Georgoulias, Vassilis|Souglakos, John | ||||||||||
| PMID: | 21283802 | ||||||||||
| 7. | |||||||||||
| Journal: | BMC Cancer. 2012 Mar 13;12:88. | ||||||||||
| Title: | Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases. | ||||||||||
| Author: | Kuramochi, Hidekazu|Nakajima, Go|Kaneko, Yuka|Nakamura, Ayako|Inoue, Yuji|Yamamoto, Masakazu|Hayashi, Kazuhiko | ||||||||||
| PMID: | 22409860 | ||||||||||
| 8. | |||||||||||
| Journal: | J Clin Invest. 2013 Apr;123(4):1428-43. | ||||||||||
| Title: | Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK. | ||||||||||
| Author: | Neufert, Clemens|Becker, Christoph|Tureci, Ozlem|Waldner, Maximilian J|Backert, Ingo|Floh, Katharina|Atreya, Imke|Leppkes, Moritz|Jefremow, Andre|Vieth, Michael|Schneider-Stock, Regine|Klinger, Patricia|Greten, Florian R|Threadgill, David W|Sahin, Ugur|Ne | ||||||||||
| PMID: | 23549083 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2. | ||||||||||
| Title: | The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab. | ||||||||||
| Author: | Strimpakos, Alexios|Pentheroudakis, George|Kotoula, Vassiliki|De Roock, Wendy|Kouvatseas, George|Papakostas, Pavlos|Makatsoris, Thomas|Papamichael, Demetris|Andreadou, Anna|Sgouros, Joseph|Zizi-Sermpetzoglou, Adamantia|Kominea, Athina|Televantou, Despina| | ||||||||||
| PMID: | 24050852 | ||||||||||
| 10. | |||||||||||
| Journal: | Harefuah. 2013 Jun;152(6):326-9, 369. | ||||||||||
| Title: | [Correlation between the presence of Kras mutation and the presence of the proteins epiregulin and amphiregulin in colon cancer tissue]. | ||||||||||
| Author: | Levi, Yosef|Barshack, Iris|Avivi, Kamila|Bar-ILan, Dalia|Gutman, Mordechai|Aderka, Dan|Berger, Raanan|Yacobi, Rinat | ||||||||||
| PMID: | 23885463 | ||||||||||
| 11. | |||||||||||
| Journal: | BMC Cancer. 2013 Feb 2;13:49. | ||||||||||
| Title: | Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes. | ||||||||||
| Author: | Pentheroudakis, George|Kotoula, Vassiliki|De Roock, Wendy|Kouvatseas, George|Papakostas, Pavlos|Makatsoris, Thomas|Papamichael, Demetris|Xanthakis, Ioannis|Sgouros, Joseph|Televantou, Despina|Kafiri, Georgia|Tsamandas, Athanassios C|Razis, Evangelia|Galan | ||||||||||
| PMID: | 23374602 | ||||||||||
| 12. | |||||||||||
| Journal: | Pharmacogenomics J. 2014 Jun;14(3):256-62. | ||||||||||
| Title: | Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan. | ||||||||||
| Author: | Sebio, A|Paez, D|Salazar, J|Berenguer-Llergo, A|Pare-Brunet, L|Lasa, A|Del Rio, E|Tobena, M|Martin-Richard, M|Baiget, M|Barnadas, A | ||||||||||
| PMID: | 23959273 | ||||||||||
| 13. | |||||||||||
| Journal: | Br J Cancer. 2014 Feb 4;110(3):648-55. | ||||||||||
| Title: | Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer. | ||||||||||
| Author: | Jonker, D J|Karapetis, C S|Harbison, C|O'Callaghan, C J|Tu, D|Simes, R J|Malone, D P|Langer, C|Tebbutt, N|Price, T J|Shapiro, J|Siu, L L|Wong, R P W|Bjarnason, G|Moore, M J|Zalcberg, J R|Khambata-Ford, S | ||||||||||
| PMID: | 24335920 | ||||||||||
| 14. | |||||||||||
| Journal: | JAMA Oncol. 2016 Feb 11. pii: 2490542. | ||||||||||
| Title: | Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer. | ||||||||||
| Author: | Seligmann, Jenny F|Elliott, Faye|Richman, Susan D|Jacobs, Bart|Hemmings, Gemma|Brown, Sarah|Barrett, Jennifer H|Tejpar, Sabine|Quirke, Philip|Seymour, Matthew T | ||||||||||
| PMID: | 26867820 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 23;7(34):55890-55899. | ||||||||||
| Title: | Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients. | ||||||||||
| Author: | Jing, Chen|Jin, Yang Han|You, Zhai|Qiong, Qian|Jun, Zhou | ||||||||||
| PMID: | 27344184 | ||||||||||
| 16. | |||||||||||
| Journal: | BMC Cancer. 2016 Jun 13;16:366. | ||||||||||
| Title: | PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study. | ||||||||||
| Author: | Kuramochi, Hidekazu|Nakamura, Ayako|Nakajima, Go|Kaneko, Yuka|Araida, Tatsuo|Yamamoto, Masakazu|Hayashi, Kazuhiko | ||||||||||
| PMID: | 27296289 | ||||||||||
| 17. | |||||||||||
| Journal: | Br J Cancer. 2016 Jun 14;114(12):1352-61. | ||||||||||
| Title: | Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer. | ||||||||||
| Author: | Lee, Michael S|McGuffey, Elizabeth J|Morris, Jeffrey S|Manyam, Ganiraju|Baladandayuthapani, Veerabahdran|Wei, Wei|Morris, Van K|Overman, Michael J|Maru, Dipen M|Jiang, Zhi-Qin|Hamilton, Stanley R|Kopetz, Scott | ||||||||||
| PMID: | 27272216 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncogene. 2016 Dec 15;35(50):6403-6415. | ||||||||||
| Title: | Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter. | ||||||||||
| Author: | Qu, X|Sandmann, T|Frierson, H Jr|Fu, L|Fuentes, E|Walter, K|Okrah, K|Rumpel, C|Moskaluk, C|Lu, S|Wang, Y|Bourgon, R|Penuel, E|Pirzkall, A|Amler, L|Lackner, M R|Tabernero, J|Hampton, G M|Kabbarah, O | ||||||||||
| PMID: | 27270421 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Med Rep. 2016 Apr;13(4):3514-20. | ||||||||||
| Title: | Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer. | ||||||||||
| Author: | Nagaoka, Tomoko|Kitaura, Kazutaka|Miyata, Yukinaga|Kumagai, Kenichi|Kaneda, Goro|Kanazawa, Hideki|Suzuki, Satsuki|Hamada, Yoshiki|Suzuki, Ryuji | ||||||||||
| PMID: | 26935861 | ||||||||||
| 20. | |||||||||||
| Journal: | JAMA Oncol. 2016 Feb 11. pii: 2490539. | ||||||||||
| Title: | AREG and EREG as Predictive Biomarkers for RAS Wild-Type Colorectal Cancer Treated With Panitumumab: A Fresh Approach to an Old Puzzle. | ||||||||||
| Author: | Smyth, Elizabeth C|Khan, Khurum|Cunningham, David | ||||||||||
| PMID: | 26869404 | ||||||||||
| 21. | |||||||||||
| Journal: | Int J Cancer. 2017 Jan 15;140(2):431-439. | ||||||||||
| Title: | Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial. | ||||||||||
| Author: | Sclafani, Francesco|Kim, Tae Y|Cunningham, David|Kim, Tae W|Tabernero, Josep|Schmoll, Hans J|Roh, Jae K|Kim, Sun Y|Park, Young S|Guren, Tormod K|Hawkes, Eliza|Clarke, Stephen J|Ferry, David|Frodin, Jan-Erik|Ayers, Mark|Nebozhyn, Michael|Peckitt, Clare|Lob | ||||||||||
| PMID: | 27681944 | ||||||||||
| 22. | |||||||||||
| Journal: | PLoS One. 2017 Jul 7;12(7):e0180834. | ||||||||||
| Title: | MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis. | ||||||||||
| Author: | Hennenberg, Eva Maria|Eyking, Annette|Reis, Henning|Cario, Elke | ||||||||||
| PMID: | 28686677 | ||||||||||
| 23. | |||||||||||
| Journal: | Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Dec 18;49(6):931-936. | ||||||||||
| Title: | [Mechanism of cross talk between tissue factor/active coagulation factor VII and epidermal growth factor receptor signalings in colon cancer cells in culture]. | ||||||||||
| Author: | Chen, H K|Dai, Y|Wu, T|Wang, X|Wan, Y L|Tang, J Q | ||||||||||
| PMID: | 29263461 | ||||||||||
| 24. | |||||||||||
| Journal: | JAMA Oncol. 2018 Apr 1;4(4):564-568. | ||||||||||
| Title: | Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. | ||||||||||
| Author: | Seligmann, Jenny F|Hatch, Ace J|Richman, Susan D|Elliott, Faye|Jacobs, Bart|Brown, Sarah|Hurwitz, Herbert|Barrett, Jennifer H|Quirke, Philip|Nixon, Andrew B|Seymour, Matthew T | ||||||||||
| PMID: | 29075780 | ||||||||||
| 25. | |||||||||||
| Journal: | BMC Cancer. 2018 May 3;18(1):517. | ||||||||||
| Title: | microRNA-451a regulates colorectal cancer proliferation in response to radiation. | ||||||||||
| Author: | Ruhl, Rebecca|Rana, Shushan|Kelley, Katherine|Espinosa-Diez, Cristina|Hudson, Clayton|Lanciault, Christian|Thomas, Charles R Jr|Liana Tsikitis, V|Anand, Sudarshan | ||||||||||
| PMID: | 29720118 | ||||||||||
| 26. | |||||||||||
| Journal: | Cell Physiol Biochem. 2018;48(2):475-490. | ||||||||||
| Title: | Distinguishable Prognostic Signatures of Left- and Right-Sided Colon Cancer: a Study Based on Sequencing Data. | ||||||||||
| Author: | Liang, Liang|Zeng, Jiang-Hui|Qin, Xin-Gan|Chen, Jun-Qiang|Luo, Dian-Zhong|Chen, Gang | ||||||||||
| PMID: | 30016783 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2018 Sep 25. | ||||||||||
| Title: | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer. | ||||||||||
| Author: | Bormann, Felix|Stinzing, Sebastian|Tierling, Sascha|Morkel, Markus|Rivera Markelova, Maria|Walter, Jorn|Weichert, Wilko|Rossner, Florian|Kuhn, Natalia|Perner, Juliane|Dietz, Johanna|Ispasanie, Sylvia|Dietel, Manfred|Schafer, Reinhold|Heinemann, Volker|Ser | ||||||||||
| PMID: | 30252132 | ||||||||||