Primary Site >> Colorectal Cancer

Gene >> EREG

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Ref: Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.
PMID: 11156386
Ref: Canonical WNT signaling pathway and human AREG.
PMID: 16685431
Ref: Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
PMID: 19738126
Ref: Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes.
PMID: 20570135
Ref: Amphiregulin and epiregulin expression in colorectal carcinoma and the correlation with clinicopathological characteristics.
PMID: 20631481
Ref: Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients.
PMID: 21283802
Ref: Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases.
PMID: 22409860
Ref: Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
PMID: 23374602
Ref: Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK.
PMID: 23549083
Ref: [Correlation between the presence of Kras mutation and the presence of the proteins epiregulin and amphiregulin in colon cancer tissue].
PMID: 23885463
Ref: The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
PMID: 24050852
Ref: Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan.
PMID: 23959273
Ref: Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer.
PMID: 24335920
Ref: Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.
PMID: 26867820
Ref: AREG and EREG as Predictive Biomarkers for RAS Wild-Type Colorectal Cancer Treated With Panitumumab: A Fresh Approach to an Old Puzzle.
PMID: 26869404
Ref: Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.
PMID: 26935861
Ref: Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.
PMID: 27270421
Ref: Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
PMID: 27272216
Ref: PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
PMID: 27296289
Ref: Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients.
PMID: 27344184
Ref: Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial.
PMID: 27681944
Ref: MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis.
PMID: 28686677
Ref: [Mechanism of cross talk between tissue factor/active coagulation factor VII and epidermal growth factor receptor signalings in colon cancer cells in culture].
PMID: 29263461
Ref: Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.
PMID: 29075780
Ref: microRNA-451a regulates colorectal cancer proliferation in response to radiation.
PMID: 29720118
Ref: Distinguishable Prognostic Signatures of Left- and Right-Sided Colon Cancer: a Study Based on Sequencing Data.
PMID: 30016783
Ref: Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
PMID: 30252132