Primary Site >> Colorectal Cancer

Gene >> ERBB4

Journal: Oncogene. 1997 Nov 27;15(22):2705-16.
Title: ErbB kinases and NDF signaling in human prostate cancer cells.
Author: Grasso, A W|Wen, D|Miller, C M|Rhim, J S|Pretlow, T G|Kung, H J
PMID: 9400997
Journal: Semin Oncol. 2001 Oct;28(5 Suppl 16):27-32.
Title: The role of HER2 in angiogenesis.
Author: Kumar, R|Yarmand-Bagheri, R
PMID: 11706393
Journal: Eur J Cancer. 2002 May;38(8):1065-71.
Title: Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery.
Author: Lee, J C|Wang, S-T|Chow, N-H|Yang, H-B
PMID: 12008194
Journal: Biochem Biophys Res Commun. 2004 Jun 18;319(1):1-11.
Title: The ErbB/HER receptor protein-tyrosine kinases and cancer.
Author: Roskoski, Robert Jr
PMID: 15158434
Journal:
Title: (99m)Tc-Cys-Gly-Gly-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641196
Journal:
Title: (111)In-Benzyl-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-ZHER2:342
Author: Leung, Kam
PMID: 20641264
Journal:
Title: BODIPY-FL-neutravidin-biotin-Cetuximab
Author: Leung, Kam
PMID: 20641313
Journal:
Title: Trastuzumab-manganese-doped iron oxide nanoparticles
Author: Leung, Kam
PMID: 20641351
Journal:
Title: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid- Affibody ZHER2:342-pep2
Author: Leung, Kam
PMID: 20641379
Journal:
Title: Cy5.5-Trastuzumab
Author: Leung, Kam
PMID: 20641392
Journal:
Title: (111)In-Diethylenetriamine pentaacetic acid-pertuzumab
Author: Leung, Kam
PMID: 20641430
Journal:
Title: (111)In-CHX-A"-diethylenepentaacetic acid-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641462
Journal:
Title: Trastuzumab-rhodamine green
Author: Leung, Kam
PMID: 20641468
Journal:
Title: (111)In-CHX-A"-Diethylenetriamine pentaacetic acid-(ZEGFR:955)2
Author: Leung, Kam
PMID: 20641502
Journal:
Title: (111)In-Benzyl-diethylenetriaminepentaacetic acid-ZHER2:342
Author: Leung, Kam
PMID: 20641524
Journal:
Title: [O-(11)C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline
Author: Leung, Kam
PMID: 20641571
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-cetuximab
Author: Leung, Kam
PMID: 20641633
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Epidermal growth factor
Author: Leung, Kam
PMID: 20641634
Journal:
Title: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-AB.Fab4D5
Author: Leung, Kam
PMID: 20641705
Journal:
Title: Quantum dot-trastuzumab
Author: Leung, Kam
PMID: 20641720
Journal:
Title: (99m)Tc-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641788
Journal:
Title: IRDye 800CW-Epidermal growth factor
Author: Leung, Kam
PMID: 20641801
Journal:
Title: (111)In-BZ-Diethylenetriaminepentaacetic acid-ZEGFR:1907
Author: Leung, Kam
PMID: 20641849
Journal:
Title: (177)Lu-Labeled humanized monoclonal antibody against human epidermal growth factor receptor 2
Author: Chopra, Arvind
PMID: 20641866
Journal:
Title: Cy5.5-Epidermal growth factor
Author: Leung, Kam
PMID: 20641899
Journal:
Title: (111)In-1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641906
Journal:
Title: (99m)Tc-Mercaptoacetyl-Ser-Ser-Ser-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641924
Journal:
Title: (99m)Tc-Mercaptoacetyl-Gly-Gly-Gly-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641926
Journal:
Title: (99m)Tc-Mercaptoacetyl-Glu-Glu-Glu-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641930
Journal:
Title: (125)I-Labeled anti-epidermal growth factor receptor human Fab antibody fragment
Author: Leung, Kam
PMID: 20642017
Journal:
Title: Alexa Fluor 750-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 20662137
Journal:
Title: DY-682-Albumin-binding domain-fused-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 20845546
Journal:
Title: IRDye 800-Anti-epidermal growth factor receptor Affibody
Author: Leung, Kam
PMID: 20845547
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-panitumumab
Author: Leung, Kam
PMID: 20945561
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2
Author: Leung, Kam
PMID: 21086574
Journal:
Title: (86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-cetuximab
Author: Leung, Kam
PMID: 21086575
Journal:
Title: Alexa Fluor 750-albumin-binding domain-fused-(ZHER2:342)2 Affibody
Author: Leung, Kam
PMID: 21491705
Journal:
Title: (124)I-Labeled anti-HER2-specific C6.5 diabody
Author: Leung, Kam
PMID: 21834183
Journal:
Title: (86)Y-CHX-A''-diethylenetriamine pentaacetic acid-panitumumab
Author: Leung, Kam
PMID: 22171389
Journal:
Title: (18)F-1,4,7-Triazacyclononane-1,4,7-triacetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395
Author: Leung, Kam
PMID: 22479718
Journal:
Title: (89)Zr-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author: Leung, Kam
PMID: 22696779
Journal:
Title: (68)Ga-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author: Leung, Kam
PMID: 22696780
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787682
Journal:
Title: (64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly) -Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787683
Journal:
Title: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787684
Journal:
Title: IRDye 800CW-Anti-epidermal growth factor receptor nanobody 7D12
Author: Leung, Kam
PMID: 22787693
Journal:
Title: (99m)Tc(CO)3-Anti-epidermal growth factor receptor nanobody 8B6
Author: Leung, Kam
PMID: 22787694
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-epidermal growth factor receptor-binding fibronectin domain E13.4.3'
Author: Leung, Kam
PMID: 22896860
Journal:
Title: Cy5.5-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 22973578
Journal:
Title: [(111)In-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-10-maleimidoethylacetamide-Cys(61)]-Affibody ZHER2:2395
Author: Leung, Kam
PMID: 22993871
Journal:
Title: (111)In-2-(4,7,10-Tris(carboxymethyl)-1,4,7,10-tetracyclododecan-1-yl)pentanedioi c acid-Trastuzumab
Author: Leung, Kam
PMID: 22993872
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23035309
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidethylacetamide-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23035311
Journal:
Title: QD800-Polyethylene glycol-Cys-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 23101053
Journal:
Title: ZHER2:342 Affibody-polyethylene glycol-superparamagnetic iron oxide nanoparticles
Author: Leung, Kam
PMID: 23101054
Journal:
Title: N-[2-(4-[(18)F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23136679
Journal:
Title: (177)Lu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23166961
Journal:
Title: Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH2
Author: Leung, Kam
PMID: 23166962
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-HER2-specific Affibody ZHER2:2891
Author: Leung, Kam
PMID: 23256220
Journal:
Title: N(epsilon)-(3-[(131)I]Iodobenzoyl)-Lys(5)-N(alpha)-maleimido-Gly(1)-GEEEK-anti-HE R2 nanobody 5F7GGC
Author: Leung, Kam
PMID: 23556153
Journal:
Title: QD800-Anti-epidermal growth factor receptor monoclonal antibody nanoparticles
Author: Leung, Kam
PMID: 23586108
Journal:
Title: IRDye 800-albumin-binding domain-fused-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 23785735
Journal: Int J Cancer. 2006 Mar 15;118(6):1426-9.
Title: Somatic mutations of the ERBB4 kinase domain in human cancers.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Wang, Young Pil|Jo, Keon Hyun|Moon, Seok Whan|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 16187281
Journal: BMC Cancer. 2006 Feb 28;6:46.
Title: Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas.
Author: Kountourakis, Panteleimon|Pavlakis, Kitty|Psyrri, Amanda|Rontogianni, Dimitra|Xiros, Nikolaos|Patsouris, Efstratios|Pectasides, Dimitrios|Economopoulos, Theofanis
PMID: 16507107
Journal: Oncogene. 2007 Mar 29;26(14):2133-5. Epub 2006 Oct 2.
Title: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.
Author: Shao, R-X|Kato, N|Lin, L-J|Muroyama, R|Moriyama, M|Ikenoue, T|Watabe, H|Otsuka, M|Guleng, B|Ohta, M|Tanaka, Y|Kondo, S|Dharel, N|Chang, J-H|Yoshida, H|Kawabe, T|Omata, M
PMID: 17016444
Journal: Clin Cancer Res. 2007 Dec 15;13(24):7506-14.
Title: A novel polymorphism in the promoter region of ERBB4 is associated with breast and colorectal cancer risk.
Author: Rokavec, Matjaz|Justenhoven, Christina|Schroth, Werner|Istrate, Monica Adina|Haas, Susanne|Fischer, Hans-Peter|Vollmert, Caren|Illig, Thomas|Hamann, Ute|Ko, Yon-Dschun|Glavac, Damjan|Brauch, Hiltrud
PMID: 18094435
Journal: PLoS One. 2008 Jun 11;3(6):e2392.
Title: Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays.
Author: Soreq, Lilach|Gilboa-Geffen, Adi|Berrih-Aknin, Sonia|Lacoste, Paul|Darvasi, Ariel|Soreq, Eyal|Bergman, Hagai|Soreq, Hermona
PMID: 18545673
Journal: Int J Colorectal Dis. 2009 Sep;24(9):1059-68.
Title: ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery.
Author: Baiocchi, Glauco|Lopes, Ademar|Coudry, Renata A|Rossi, Benedito M|Soares, Fernando A|Aguiar, Samuel|Guimaraes, Gustavo C|Ferreira, Fabio O|Nakagawa, Wilson T
PMID: 19390858
Journal: Anticancer Res. 2009 May;29(5):1489-94.
Title: ErbB 1-4 expression alterations in primary colorectal cancers and their corresponding metastases.
Author: Ljuslinder, Ingrid|Malmer, Beatrice|Isaksson-Mettavainio, Martin|Oberg, Ake|Henriksson, Roger|Stenling, Roger|Palmqvist, Richard
PMID: 19443355
Journal: J Clin Invest. 2009 Sep;119(9):2702-13.
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Author: Lee, Daekee|Yu, Ming|Lee, Eunjung|Kim, Hyunok|Yang, Yanan|Kim, Kyoungmi|Pannicia, Christina|Kurie, Jonathan M|Threadgill, David W
PMID: 19690388
Journal: Invest New Drugs. 2010 Jun;28(3):350-2.
Title: Acute left ventricular dysfunction induced by a panHER and VEGFR tyrosine kinase inhibitor in a phase I trial.
Author: Bahleda, Rastislav|Massard, Christophe|Soria, Jean-Charles|Izzedine, Hassan|Cohen, Ariel|Ederhy, Stephane
PMID: 19396400
Journal: Exp Cell Res. 2010 Apr 15;316(7):1083-100.
Title: Mechanisms of resistance to HER family targeting antibodies.
Author: Kruser, Tim J|Wheeler, Deric L
PMID: 20064507
Journal: Mol Cancer. 2010 Oct 14;9:273.
Title: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.
Author: Rigo, Antonella|Gottardi, Michele|Zamo, Alberto|Mauri, Pierluigi|Bonifacio, Massimiliano|Krampera, Mauro|Damiani, Ernesto|Pizzolo, Giovanni|Vinante, Fabrizio
PMID: 20946648
Journal: Cancer Biomark. 2010-2011;8(2):61-5.
Title: The EGFR R521K polymorphism influences the risk to develop colorectal cancer.
Author: Martinelli, Marcella|Ugolini, Giampaolo|Scapoli, Luca|Rivetti, Stefano|Lauriola, Mattia|Mattei, Gabriella|Rosati, Giancarlo|Montroni, Isacco|Manaresi, Alessio|Zattoni, Davide|Taffurelli, Mario|Solmi, Rossella
PMID: 21896992
Journal: Biochem Biophys Res Commun. 2011 Aug 12;411(4):751-6.
Title: Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
Author: Yu, Zhiwei|Cui, Binbin|Jin, Yinghu|Chen, Haipeng|Wang, Xishan
PMID: 21782788
Journal: Mol Med Rep. 2011 Nov-Dec;4(6):1151-5.
Title: The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma.
Author: Ebi, Masahide|Kataoka, Hiromi|Shimura, Takaya|Hirata, Yoshikazu|Mizushima, Takashi|Mizoshita, Tsutomu|Tanaka, Mamoru|Tsukamoto, Hironobu|Ozeki, Keiji|Tanida, Satoshi|Kamiya, Takeshi|Inagaki, Hiroshi|Joh, Takashi
PMID: 21805036
Journal: Jpn J Clin Oncol. 2012 Apr;42(4):278-86.
Title: Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study.
Author: Ito, Yoshinori|Suenaga, Mitsukuni|Hatake, Kiyohiko|Takahashi, Shunji|Yokoyama, Masahiro|Onozawa, Yusuke|Yamazaki, Kentaro|Hironaka, Shuichi|Hashigami, Kiyoshi|Hasegawa, Hirotaka|Takenaka, Nobuko|Boku, Narikazu
PMID: 22371427
Journal: Expert Opin Investig Drugs. 2013 Mar;22(3):341-56.
Title: Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers.
Author: Desai, Monica Dandona|Saroya, Bikramajit Singh|Lockhart, Albert Craig
PMID: 23316969
Journal: Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2.
Title: The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
Author: Strimpakos, Alexios|Pentheroudakis, George|Kotoula, Vassiliki|De Roock, Wendy|Kouvatseas, George|Papakostas, Pavlos|Makatsoris, Thomas|Papamichael, Demetris|Andreadou, Anna|Sgouros, Joseph|Zizi-Sermpetzoglou, Adamantia|Kominea, Athina|Televantou, Despina|
PMID: 24050852
Journal: Drugs Today (Barc). 2013 Sep;49(9):523-35.
Title: Afatinib for the treatment of patients with EGFR-positive non-small cell lung cancer.
Author: Bowles, D W|Weickhardt, A|Jimeno, A
PMID: 24086949
Journal: Pharmacol Res. 2014 Jan;79:34-74.
Title: The ErbB/HER family of protein-tyrosine kinases and cancer.
Author: Roskoski, Robert Jr
PMID: 24269963
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun;387(6):505-21.
Title: A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.
Author: Modjtahedi, Helmout|Cho, Byoung Chul|Michel, Martin C|Solca, Flavio
PMID: 24643470
Journal: Clin Cancer Res. 2014 Aug 1;20(15):4115-28.
Title: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells.
Author: Bae, Jeong A|Yoon, Somy|Park, So-Yeon|Lee, Jae Hyuk|Hwang, Jun-Eul|Kim, Hangun|Seo, Young-Woo|Cha, Yoon Jin|Hong, Sung Pil|Kim, Hoguen|Chung, Ik Joo|Kim, Kyung Keun
PMID: 24893630
Journal: Cancer Biomark. 2014;14(6):435-9.
Title: Genetic variation of ErbB4 confers risk of colorectal cancer in a Chinese Han population.
Author: Gao, Xueren|Zhang, Shulong|Zhu, Zhansheng
PMID: 25335735
Journal: BMC Cancer. 2014 Nov 22;14:863.
Title: Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer.
Author: Mitsui, Keigo|Yonezawa, Masaoki|Tatsuguchi, Atsushi|Shinji, Seiichi|Gudis, Katya|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu
PMID: 25416285
Journal: J Appl Genet. 2015 May;56(2):185-92.
Title: Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.
Author: Szmida, Elzbieta|Karpinski, Pawel|Leszczynski, Przemyslaw|Sedziak, Tomasz|Kielan, Wojciech|Ostasiewicz, Pawel|Sasiadek, Maria M
PMID: 25366420
Journal: Acta Oncol. 2015 Apr;54(4):480-6.
Title: HER3 expression in primary colorectal cancer including corresponding metastases in lymph node and liver.
Author: Ledel, Frida|Stenstedt, Kristina|Hallstrom, Marja|Ragnhammar, Peter|Edler, David
PMID: 25601452
Journal: Biochem Biophys Res Commun. 2015 Feb 27;458(1):52-6.
Title: Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.
Author: Kogita, Akihiro|Yoshioka, Yasumasa|Sakai, Kazuko|Togashi, Yosuke|Sogabe, Shunsuke|Nakai, Takuya|Okuno, Kiyotaka|Nishio, Kazuto
PMID: 25623536
Journal: Carcinogenesis. 2015 Jul;36(7):710-8.
Title: ERBB4 is over-expressed in human colon cancer and enhances cellular transformation.
Author: Williams, Christopher S|Bernard, Jessica K|Demory Beckler, Michelle|Almohazey, Dana|Washington, Mary Kay|Smith, Jesse J|Frey, Mark R
PMID: 25916654
Journal: Am J Cancer Res. 2015 Jan 15;5(2):560-74. eCollection 2015.
Title: Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells.
Author: Grunt, Thomas W|Hebar, Alexandra|Laffer, Sylvia|Wagner, Renate|Peter, Barbara|Herrmann, Harald|Graf, Alexandra|Bilban, Martin|Posch, Martin|Hoermann, Gregor|Mayerhofer, Matthias|Eisenwort, Gregor|Zielinski, Christoph C|Selzer, Edgar|Valent, Peter
PMID: 25973297
Journal: Clin Cancer Res. 2016 Mar 1;22(5):1284-94.
Title: Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss.
Author: Bae, Jeong A|Kho, Dhong Hyo|Sun, Eun Gene|Ko, Yoo-Seung|Yoon, Somy|Lee, Kyung Hwa|Ahn, Kyu Youn|Lee, Jae Hyuk|Joo, Young Eun|Chung, Ik Joo|Lee, Sug Hyung|Kim, Hangun|Kim, Kyung Keun
PMID: 26527747
Journal: J Clin Pathol. 2016 Sep;69(9):767-71.
Title: Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author: Malapelle, Umberto|Pisapia, Pasquale|Sgariglia, Roberta|Vigliar, Elena|Biglietto, Maria|Carlomagno, Chiara|Giuffre, Giuseppe|Bellevicine, Claudio|Troncone, Giancarlo
PMID: 26797410
Journal: Acta Oncol. 2016 Jul;55(7):875-80.
Title: HER3 expression is correlated to distally located and low-grade colon cancer.
Author: Ledel, Frida|Stenstedt, Kristina|Hallstrom, Marja|Ragnhammar, Peter|Edler, David
PMID: 26863446
Journal: Pharmacol Ther. 2016 Oct;166:71-83.
Title: Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer.
Author: De Pauw, I|Wouters, A|Van den Bossche, J|Peeters, M|Pauwels, P|Deschoolmeester, V|Vermorken, J B|Lardon, F
PMID: 27373506
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: Gastroenterol Res Pract. 2016;2016:3481578.
Title: Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer.
Author: Kripp, Melanie|Merx, Kirsten|Wirtz, Ralph Markus|Gaiser, Timo|Eidt, Sebastian|Schwaab, Juliana|Post, Stefan|Wenz, Frederik|Hochhaus, Andreas|Hofheinz, Ralf-Dieter|Erben, Philipp
PMID: 27610130
Journal: Mol Ther. 2016 Dec;24(12):2064-2077.
Title: Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer.
Author: Yue, Ben|Cai, Donglan|Liu, Chenchen|Fang, Changyi|Yan, Dongwang
PMID: 27633443
Journal: Mol Carcinog. 2017 Mar;56(3):1068-1081.
Title: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation.
Author: Sun, Eun Gene|Lee, Kyung Hwa|Ko, Yoo-Seung|Choi, Hui Jeong|Yang, Jung-In|Lee, Jae Hyuk|Chung, Ik Joo|Paek, Yun-Woong|Kim, Hangun|Bae, Jeong A|Kim, Kyung Keun
PMID: 27648936
Journal: Oncotarget. 2017 Jun 13;8(51):89284-89306.
Title: A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer.
Author: Mota, Jose Mauricio|Collier, Katharine Ann|Barros Costa, Ricardo Lima|Taxter, Timothy|Kalyan, Aparna|Leite, Caio A|Chae, Young Kwang|Giles, Francis J|Carneiro, Benedito A
PMID: 29179520
Journal: Mol Med Rep. 2018 Mar;17(3):4619-4626.
Title: miR1273g3p promotes proliferation, migration and invasion of LoVo cells via cannabinoid receptor 1 through activation of ERBB4/PIK3R3/mTOR/S6K2 signaling pathway.
Author: Li, Min|Qian, Xiaoping|Zhu, Mingzhen|Li, Aiyi|Fang, Mingzhi|Zhu, Yong|Zhang, Jingyu
PMID: 29328379
Journal: Cancer Res Treat. 2018 Jan 17. pii: crt.2017.487.
Title: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.
Author: Yun, Sumi|Kwak, Yoonjin|Nam, Soo Kyung|Seo, An Na|Oh, Heung-Kwon|Kim, Duck-Woo|Kang, Sung-Bum|Lee, Hye Seung
PMID: 29361822
Journal: Oncol Lett. 2018 May;15(5):6629-6635.
Title: HER4 isoform CYT2 and its ligand NRG1III are expressed at high levels in human colorectal cancer.
Author: Guo, Yan|Duan, Zhihui|Jia, Yitao|Ren, Chaoying|Lv, Jian|Guo, Peng|Zhao, Wujie|Wang, Bin|Zhang, Suqiao|Li, Yaxing|Li, Zhongxin
PMID: 29616125
Journal: BMC Cancer. 2018 Jun 27;18(1):695.
Title: Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author: Molnar, Bela|Galamb, Orsolya|Peterfia, Balint|Wichmann, Barnabas|Csabai, Istvan|Bodor, Andras|Kalmar, Alexandra|Szigeti, Krisztina Andrea|Bartak, Barbara Kinga|Nagy, Zsofia Brigitta|Valcz, Gabor|Patai, Arpad V|Igaz, Peter|Tulassay, Zsolt
PMID: 29945573