Primary Site >> Colorectal Cancer
Gene >> ERBB4
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Ref: ErbB kinases and NDF signaling in human prostate cancer cells. PMID: 9400997 |
Ref: The role of HER2 in angiogenesis. PMID: 11706393 |
Ref: Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery. PMID: 12008194 |
Ref: The ErbB/HER receptor protein-tyrosine kinases and cancer. PMID: 15158434 Ref: (99m)Tc-Cys-Gly-Gly-Affibody ZHER2:342 PMID: 20641196 Ref: (111)In-Benzyl-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-ZHER2:342 PMID: 20641264 Ref: BODIPY-FL-neutravidin-biotin-Cetuximab PMID: 20641313 Ref: Trastuzumab-manganese-doped iron oxide nanoparticles PMID: 20641351 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid- Affibody ZHER2:342-pep2 PMID: 20641379 Ref: Cy5.5-Trastuzumab PMID: 20641392 Ref: (111)In-Diethylenetriamine pentaacetic acid-pertuzumab PMID: 20641430 Ref: (111)In-CHX-A"-diethylenepentaacetic acid-Affibody ZHER2:2395-Cys PMID: 20641462 Ref: Trastuzumab-rhodamine green PMID: 20641468 Ref: (111)In-CHX-A"-Diethylenetriamine pentaacetic acid-(ZEGFR:955)2 PMID: 20641502 Ref: (111)In-Benzyl-diethylenetriaminepentaacetic acid-ZHER2:342 PMID: 20641524 Ref: [O-(11)C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline PMID: 20641571 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-cetuximab PMID: 20641633 Ref: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Epidermal growth factor PMID: 20641634 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-AB.Fab4D5 PMID: 20641705 Ref: Quantum dot-trastuzumab PMID: 20641720 Ref: (99m)Tc-Affibody ZHER2:2395-Cys PMID: 20641788 Ref: IRDye 800CW-Epidermal growth factor PMID: 20641801 Ref: (111)In-BZ-Diethylenetriaminepentaacetic acid-ZEGFR:1907 PMID: 20641849 Ref: (177)Lu-Labeled humanized monoclonal antibody against human epidermal growth factor receptor 2 PMID: 20641866 Ref: Cy5.5-Epidermal growth factor PMID: 20641899 Ref: (111)In-1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395-Cys PMID: 20641906 Ref: (99m)Tc-Mercaptoacetyl-Ser-Ser-Ser-Affibody ZHER2:342 PMID: 20641924 Ref: (99m)Tc-Mercaptoacetyl-Gly-Gly-Gly-Affibody ZHER2:342 PMID: 20641926 Ref: (99m)Tc-Mercaptoacetyl-Glu-Glu-Glu-Affibody ZHER2:342 PMID: 20641930 Ref: (125)I-Labeled anti-epidermal growth factor receptor human Fab antibody fragment PMID: 20642017 Ref: Alexa Fluor 750-ZHER2:342 Affibody PMID: 20662137 Ref: DY-682-Albumin-binding domain-fused-ZHER2:342 Affibody PMID: 20845546 Ref: IRDye 800-Anti-epidermal growth factor receptor Affibody PMID: 20845547 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-panitumumab PMID: 20945561 Ref: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2 PMID: 21086574 Ref: (86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-cetuximab PMID: 21086575 Ref: Alexa Fluor 750-albumin-binding domain-fused-(ZHER2:342)2 Affibody PMID: 21491705 Ref: (124)I-Labeled anti-HER2-specific C6.5 diabody PMID: 21834183 Ref: (86)Y-CHX-A''-diethylenetriamine pentaacetic acid-panitumumab PMID: 22171389 Ref: (18)F-1,4,7-Triazacyclononane-1,4,7-triacetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395 PMID: 22479718 Ref: (89)Zr-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12 PMID: 22696779 Ref: (68)Ga-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12 PMID: 22696780 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787682 Ref: (64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly) -Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787683 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787684 Ref: IRDye 800CW-Anti-epidermal growth factor receptor nanobody 7D12 PMID: 22787693 Ref: (99m)Tc(CO)3-Anti-epidermal growth factor receptor nanobody 8B6 PMID: 22787694 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-epidermal growth factor receptor-binding fibronectin domain E13.4.3' PMID: 22896860 Ref: Cy5.5-Ac-Cys-ZEGFR:1907 PMID: 22973578 Ref: [(111)In-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-10-maleimidoethylacetamide-Cys(61)]-Affibody ZHER2:2395 PMID: 22993871 Ref: (111)In-2-(4,7,10-Tris(carboxymethyl)-1,4,7,10-tetracyclododecan-1-yl)pentanedioi c acid-Trastuzumab PMID: 22993872 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907 PMID: 23035309 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidethylacetamide-Ac-Cys-ZEGFR:1907 PMID: 23035311 Ref: QD800-Polyethylene glycol-Cys-ZHER2:342 Affibody PMID: 23101053 Ref: ZHER2:342 Affibody-polyethylene glycol-superparamagnetic iron oxide nanoparticles PMID: 23101054 Ref: N-[2-(4-[(18)F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907 PMID: 23136679 Ref: (177)Lu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907 PMID: 23166961 Ref: Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH2 PMID: 23166962 Ref: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-HER2-specific Affibody ZHER2:2891 PMID: 23256220 Ref: N(epsilon)-(3-[(131)I]Iodobenzoyl)-Lys(5)-N(alpha)-maleimido-Gly(1)-GEEEK-anti-HE R2 nanobody 5F7GGC PMID: 23556153 Ref: QD800-Anti-epidermal growth factor receptor monoclonal antibody nanoparticles PMID: 23586108 Ref: IRDye 800-albumin-binding domain-fused-ZHER2:342 Affibody PMID: 23785735 |
Ref: Somatic mutations of the ERBB4 kinase domain in human cancers. PMID: 16187281 Ref: Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas. PMID: 16507107 |
Ref: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients. PMID: 17016444 Ref: A novel polymorphism in the promoter region of ERBB4 is associated with breast and colorectal cancer risk. PMID: 18094435 |
Ref: Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays. PMID: 18545673 |
Ref: ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery. PMID: 19390858 Ref: ErbB 1-4 expression alterations in primary colorectal cancers and their corresponding metastases. PMID: 19443355 Ref: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium. PMID: 19690388 |
Ref: Acute left ventricular dysfunction induced by a panHER and VEGFR tyrosine kinase inhibitor in a phase I trial. PMID: 19396400 Ref: Mechanisms of resistance to HER family targeting antibodies. PMID: 20064507 Ref: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. PMID: 20946648 Ref: The EGFR R521K polymorphism influences the risk to develop colorectal cancer. PMID: 21896992 |
Ref: Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway. PMID: 21782788 Ref: The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma. PMID: 21805036 |
Ref: Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study. PMID: 22371427 |
Ref: Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers. PMID: 23316969 Ref: The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab. PMID: 24050852 Ref: Afatinib for the treatment of patients with EGFR-positive non-small cell lung cancer. PMID: 24086949 |
Ref: The ErbB/HER family of protein-tyrosine kinases and cancer. PMID: 24269963 Ref: A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer. PMID: 24643470 Ref: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells. PMID: 24893630 Ref: Genetic variation of ErbB4 confers risk of colorectal cancer in a Chinese Han population. PMID: 25335735 Ref: Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer. PMID: 25416285 |
Ref: Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer. PMID: 25366420 Ref: HER3 expression in primary colorectal cancer including corresponding metastases in lymph node and liver. PMID: 25601452 Ref: Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis. PMID: 25623536 Ref: ERBB4 is over-expressed in human colon cancer and enhances cellular transformation. PMID: 25916654 Ref: Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells. PMID: 25973297 |
Ref: Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss. PMID: 26527747 Ref: Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases. PMID: 26797410 Ref: HER3 expression is correlated to distally located and low-grade colon cancer. PMID: 26863446 Ref: Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer. PMID: 27373506 Ref: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing. PMID: 27568332 Ref: Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer. PMID: 27610130 Ref: Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer. PMID: 27633443 |
Ref: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation. PMID: 27648936 Ref: A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer. PMID: 29179520 |
Ref: miR1273g3p promotes proliferation, migration and invasion of LoVo cells via cannabinoid receptor 1 through activation of ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. PMID: 29328379 Ref: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer. PMID: 29361822 Ref: HER4 isoform CYT2 and its ligand NRG1III are expressed at high levels in human colorectal cancer. PMID: 29616125 Ref: Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations. PMID: 29945573 |