Primary Site >> Colorectal Cancer

Gene >> EPHX1

Journal: Recent Results Cancer Res. 1998;154:47-85.
Title: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Author: Hengstler, J G|Arand, M|Herrero, M E|Oesch, F
PMID: 10026993
Journal: Br J Cancer. 1999 Jan;79(1):168-71.
Title: Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer.
Author: Harrison, D J|Hubbard, A L|MacMillan, J|Wyllie, A H|Smith, C A
PMID: 10408710
Journal: Histochem J. 2001 Jun;33(6):329-36.
Title: Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Author: Coller, J K|Fritz, P|Zanger, U M|Siegle, I|Eichelbaum, M|Kroemer, H K|Murdter, T E
PMID: 11758809
Journal: Carcinogenesis. 2002 Nov;23(11):1839-49.
Title: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Author: Sachse, Christoph|Smith, Gillian|Wilkie, Murray J V|Barrett, Jennifer H|Waxman, Robin|Sullivan, Frank|Forman, David|Bishop, D Timothy|Wolf, C Roland
PMID: 12419832
Journal: Int J Cancer. 2004 Nov 1;112(2):259-64.
Title: Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer.
Author: Turner, Faye|Smith, Gillian|Sachse, Christoph|Lightfoot, Tracy|Garner, R Colin|Wolf, C Roland|Forman, David|Bishop, D Timothy|Barrett, Jennifer H
PMID: 15352038
Journal: Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Moreno, Victor|Gioia-Patricola, Lydie|Chabrier, Amelie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 16006997
Journal: Mol Carcinog. 2005 Sep;44(1):21-30.
Title: Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Author: Tranah, Gregory J|Chan, Andrew T|Giovannucci, Edward|Ma, Jing|Fuchs, Charles|Hunter, David J
PMID: 15924351
Journal: Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1350-2.
Title: Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk.
Author: Robien, Kim|Curtin, Karen|Ulrich, Cornelia M|Bigler, Jeannette|Samowitz, Wade|Caan, Bette|Potter, John D|Slattery, Martha L
PMID: 15894702
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):152-7.
Title: Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Author: Huang, Wen-Yi|Chatterjee, Nilanjan|Chanock, Stephen|Dean, Michael|Yeager, Meredith|Schoen, Robert E|Hou, Li-Fang|Berndt, Sonja I|Yadavalli, Sunita|Johnson, Christine C|Hayes, Richard B
PMID: 15668489
Journal: Mutat Res. 2006 Jan 29;593(1-2):39-49. Epub 2005 Jul 21.
Title: Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.
Author: van der Logt, Elise M J|Bergevoet, Saskia M|Roelofs, Hennie M J|Te Morsche, Rene H M|Dijk, Yvo van|Wobbes, Theo|Nagengast, Fokko M|Peters, Wilbert H M
PMID: 16039674
Journal: Mol Carcinog. 2006 Mar;45(3):164-74.
Title: Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics.
Author: Veeriah, Selvaraju|Kautenburger, Tanja|Habermann, Nina|Sauer, Julia|Dietrich, Helmut|Will, Frank|Pool-Zobel, Beatrice Louise
PMID: 16369997
Journal: Carcinogenesis. 2007 Feb;28(2):328-41.
Title: Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.
Author: Goode, Ellen L|Potter, John D|Bamlet, William R|Rider, David N|Bigler, Jeannette
PMID: 16926176
Journal: J Antibiot (Tokyo). 2007 Mar;60(3):211-5.
Title: Chemomicin A, a new angucyclinone antibiotic produced by Nocardia mediterranei subsp. kanglensis 1747-64.
Author: Sun, Cheng-Hang|Wang, Yue|Wang, Zheng|Zhou, Jian-Qin|Jin, Wen-Zao|You, Xue-Fu|Gao, Hong|Zhao, Li-Xun|Si, Shu-Yi|Li, Xue
PMID: 17446695
Journal: Anticancer Res. 2007 Jul-Aug;27(4C):2931-7.
Title: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Author: Kiss, Istvan|Orsos, Zsuzsa|Gombos, Katalin|Bogner, Barna|Csejtei, Andras|Tibold, Antal|Varga, Zsuzsa|Pazsit, Emese|Magda, Ingrid|Zolyomi, Annamaria|Ember, Istvan
PMID: 17695473
Journal: BMC Cancer. 2007 Dec 19;7:228.
Title: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Author: Skjelbred, Camilla F|Saebo, Mona|Hjartaker, Anette|Grotmol, Tom|Hansteen, Inger-Lise|Tveit, Kjell M|Hoff, Geir|Kure, Elin H
PMID: 18093316
Journal: Proteomics. 2008 Jan;8(1):45-61.
Title: Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.
Author: Dihal, Ashwin A|van der Woude, Hester|Hendriksen, Peter J M|Charif, Halima|Dekker, Lennard J|Ijsselstijn, Linda|de Boer, Vincent C J|Alink, Gerrit M|Burgers, Peter C|Rietjens, Ivonne M C M|Woutersen, Ruud A|Stierum, Rob H
PMID: 18095365
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3098-107.
Title: Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
Author: Cotterchio, Michelle|Boucher, Beatrice A|Manno, Michael|Gallinger, Steven|Okey, Allan B|Harper, Patricia A
PMID: 18990750
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2393-401.
Title: Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.
Author: Pande, Mala|Amos, Christopher I|Osterwisch, Daniel R|Chen, Jinyun|Lynch, Patrick M|Broaddus, Russell|Frazier, Marsha L
PMID: 18768509
Journal: Pharmacogenet Genomics. 2010 May;20(5):315-26.
Title: Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk.
Author: Northwood, Emma L|Elliott, Faye|Forman, David|Barrett, Jennifer H|Wilkie, Murray J V|Carey, Francis A|Steele, Robert J C|Wolf, Roland|Bishop, Timothy|Smith, Gillian
PMID: 20375710
Journal: Oncol Rep. 2010 Nov;24(5):1347-53.
Title: Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
Author: Hlavata, Ivona|Vrana, David|Smerhovsky, Zdenek|Pardini, Barbara|Naccarati, Alessio|Vodicka, Pavel|Novotny, Jan|Mohelnikova-Duchonova, Beatrice|Soucek, Pavel
PMID: 20878130
Journal: Mol Carcinog. 2010 Nov;49(11):974-80.
Title: Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis.
Author: Pande, Mala|Amos, Christopher I|Eng, Cathy|Frazier, Marsha L
PMID: 20886582
Journal: PLoS One. 2011 Mar 18;6(3):e14749.
Title: Putative EPHX1 enzyme activity is related with risk of lung and upper aerodigestive tract cancers: a comprehensive meta-analysis.
Author: Li, Xiang|Hu, Zheng|Qu, Xinshun|Zhu, Jiadong|Li, Lin|Ring, Brian Z|Su, Li
PMID: 21445251
Journal: Int J Cancer. 2012 Apr 15;130(8):1898-907.
Title: Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
Author: Wang, Jun|Joshi, Amit D|Corral, Roman|Siegmund, Kimberly D|Marchand, Loic Le|Martinez, Maria Elena|Haile, Robert W|Ahnen, Dennis J|Sandler, Robert S|Lance, Peter|Stern, Mariana C
PMID: 21618522
Journal: Genet Test Mol Biomarkers. 2012 May;16(5):423-8.
Title: Investigation of a possible relationship between EPHX1 gene polymorphisms and colorectal cancer in Turkish society.
Author: Sahin, Onder|Arikan, Soykan|Oltulu, Yasemin Musteri|Coskunpinar, Ender|Eren, Ayse|Cacina, Canan|Guler, Erkan|Yaylim, Ilhan
PMID: 22352736
Journal: Carcinogenesis. 2012 Jul;33(7):1332-9.
Title: Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer.
Author: Gilsing, Anne M J|Berndt, Sonja I|Ruder, Elizabeth H|Graubard, Barry I|Ferrucci, Leah M|Burdett, Laura|Weissfeld, Joel L|Cross, Amanda J|Sinha, Rashmi
PMID: 22552404
Journal: PLoS One. 2012;7(8):e43821.
Title: Systematic review and meta-analysis of the relationship between EPHX1 polymorphisms and colorectal cancer risk.
Author: Liu, Fei|Yuan, Ding|Wei, Yonggang|Wang, Wentao|Yan, Lvnan|Wen, Tianfu|Xu, Mingqing|Yang, Jiayin|Li, Bo
PMID: 22928041
Journal: Mol Carcinog. 2013 Aug;52(8):619-26.
Title: Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Author: Nisa, Hoirun|Budhathoki, Sanjeev|Morita, Makiko|Toyomura, Kengo|Nagano, Jun|Ohnaka, Keizo|Kono, Suminori|Ueki, Takashi|Tanaka, Masao|Kakeji, Yoshihiro|Maehara, Yoshihiko|Okamura, Takeshi|Ikejiri, Koji|Futami, Kitaroh|Maekawa, Takafumi|Yasunami, Yohichi|Ta
PMID: 22415791
Journal: Genet Med. 2015 Feb;17(2):131-42.
Title: Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
Author: Esteban-Jurado, Clara|Vila-Casadesus, Maria|Garre, Pilar|Lozano, Juan Jose|Pristoupilova, Anna|Beltran, Sergi|Munoz, Jenifer|Ocana, Teresa|Balaguer, Francesc|Lopez-Ceron, Maria|Cuatrecasas, Miriam|Franch-Exposito, Sebastia|Pique, Josep M|Castells, Antoni|
PMID: 25058500
Journal: World J Gastroenterol. 2016 Dec 7;22(45):9974-9983.
Title: CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms.
Author: Fernandes, Glaucia Maria M|Russo, Anelise|Proenca, Marcela Alcantara|Gazola, Nathalia Fernanda|Rodrigues, Gabriela Helena|Biselli-Chicote, Patricia Matos|Silva, Ana Elizabete|Netinho, Joao Gomes|Pavarino, Erika Cristina|Goloni-Bertollo, Eny Maria
PMID: 28018104
Journal: Exp Ther Med. 2017 Jul;14(1):338-343.
Title: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Author: Xie, Ni|Yao, Yujiang|Wan, Lili|Zhu, Ting|Liu, Litao|Yuan, Jianhui
PMID: 28672935