Primary Site >> Colorectal Cancer
Gene >> EPHX1
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Ref: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. PMID: 10026993 |
Ref: Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer. PMID: 10408710 |
Ref: Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours. PMID: 11758809 |
Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. PMID: 12419832 |
Ref: Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. PMID: 15352038 |
Ref: Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma. PMID: 15668489 Ref: Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk. PMID: 15894702 Ref: Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study. PMID: 15924351 Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. PMID: 16006997 |
Ref: Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer. PMID: 16039674 Ref: Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics. PMID: 16369997 |
Ref: Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. PMID: 16926176 Ref: Chemomicin A, a new angucyclinone antibiotic produced by Nocardia mediterranei subsp. kanglensis 1747-64. PMID: 17446695 Ref: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. PMID: 17695473 Ref: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas. PMID: 18093316 |
Ref: Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis. PMID: 18095365 Ref: Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. PMID: 18768509 Ref: Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. PMID: 18990750 |
Ref: Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk. PMID: 20375710 Ref: Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. PMID: 20878130 Ref: Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis. PMID: 20886582 |
Ref: Putative EPHX1 enzyme activity is related with risk of lung and upper aerodigestive tract cancers: a comprehensive meta-analysis. PMID: 21445251 |
Ref: Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. PMID: 21618522 Ref: Investigation of a possible relationship between EPHX1 gene polymorphisms and colorectal cancer in Turkish society. PMID: 22352736 Ref: Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer. PMID: 22552404 Ref: Systematic review and meta-analysis of the relationship between EPHX1 polymorphisms and colorectal cancer risk. PMID: 22928041 |
Ref: Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study. PMID: 22415791 |
Ref: Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer. PMID: 25058500 |
Ref: CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms. PMID: 28018104 |
Ref: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer. PMID: 28672935 |