Primary Site >> Colorectal Cancer

Gene >> EPHB3

Journal: Cell. 2002 Oct 18;111(2):251-63.
Title: Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.
Author: Batlle, Eduard|Henderson, Jeffrey T|Beghtel, Harry|van den Born, Maaike M W|Sancho, Elena|Huls, Gerwin|Meeldijk, Jan|Robertson, Jennifer|van de Wetering, Marc|Pawson, Tony|Clevers, Hans
PMID: 12408869
Journal: Cancer. 2002 Feb 15;94(4):934-9.
Title: Coexpression of ephrin-Bs and their receptors in colon carcinoma.
Author: Liu, Wenbiao|Ahmad, Syed A|Jung, Young D|Reinmuth, Niels|Fan, Fan|Bucana, Corazon D|Ellis, Lee M
PMID: 11920461
Journal: Nat Genet. 2007 Nov;39(11):1376-83. Epub 2007 Sep 30.
Title: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
Author: Cortina, Carme|Palomo-Ponce, Sergio|Iglesias, Mar|Fernandez-Masip, Juan Luis|Vivancos, Ana|Whissell, Gavin|Huma, Mireia|Peiro, Nerea|Gallego, Lourdes|Jonkheer, Suzanne|Davy, Alice|Lloreta, Josep|Sancho, Elena|Batlle, Eduard
PMID: 17906625
Journal: Epigenetics. 2007 Oct-Dec;2(4):237-43. Epub 2007 Dec 9.
Title: The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers.
Author: Wu, Qinghua|Lind, Guro E|Aasheim, Hans-Christian|Micci, Francesca|Silins, Ilvars|Trope, Claes G|Nesland, Jahn M|Lothe, Ragnhild A|Suo, Zhenhe
PMID: 18281782
Journal: Carcinogenesis. 2009 Sep;30(9):1475-86.
Title: Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.
Author: Chiu, Sou-Tyau|Chang, King-Jen|Ting, Chen-Hung|Shen, Hsi-Che|Li, Hung|Hsieh, Fon-Jou
PMID: 19483190
Journal: Int J Cancer. 2010 May 1;126(9):2003-11.
Title: The role of Eph receptors and ephrin ligands in colorectal cancer.
Author: Herath, Nirmitha I|Boyd, Andrew W
PMID: 20039322
Journal: Gut. 2010 Sep;59(9):1236-44.
Title: Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.
Author: Stange, D E|Engel, F|Longerich, T|Koo, B K|Koch, M|Delhomme, N|Aigner, M|Toedt, G|Schirmacher, P|Lichter, P|Weitz, J|Radlwimmer, B
PMID: 20479215
Journal: Epigenetics. 2011 May;6(5):610-22. Epub 2011 May 1.
Title: Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer.
Author: Ronsch, Kerstin|Jager, Marcel|Schopflin, Anja|Danciu, Mihai|Lassmann, Silke|Hecht, Andreas
PMID: 21393996
Journal: BMC Syst Biol. 2011 Feb 26;5:35.
Title: A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer.
Author: Nagaraj, Shivashankar H|Reverter, Antonio
PMID: 21352556
Journal: Cancer Res. 2011 Feb 1;71(3):1156-66.
Title: EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration.
Author: Ji, Xiao-Dan|Li, Guo|Feng, Yu-Xiong|Zhao, Jiang-Sha|Li, Jing-Jing|Sun, Zhi-Jian|Shi, Shuo|Deng, Yue-Zhen|Xu, Jun-Feng|Zhu, Yin-Qiu|Koeffler, H Phillip|Tong, Xiang-Jun|Xie, Dong
PMID: 21266352
Journal: Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4886-91.
Title: Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.
Author: Jagle, Sabine|Ronsch, Kerstin|Timme, Sylvia|Andrlova, Hana|Bertrand, Miriam|Jager, Marcel|Proske, Amelie|Schrempp, Monika|Yousaf, Afsheen|Michoel, Tom|Zeiser, Robert|Werner, Martin|Lassmann, Silke|Hecht, Andreas
PMID: 24707046
Journal: Mol Oncol. 2015 Feb;9(2):335-54.
Title: SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
Author: Ronsch, Kerstin|Jagle, Sabine|Rose, Katja|Seidl, Maximilian|Baumgartner, Francis|Freihen, Vivien|Yousaf, Afsheen|Metzger, Eric|Lassmann, Silke|Schule, Roland|Zeiser, Robert|Michoel, Tom|Hecht, Andreas
PMID: 25277775
Journal: PLoS One. 2016 Jan 25;11(1):e0147886.
Title: Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.
Author: Kuan, Chee Sian|See Too, Wei Cun|Few, Ling Ling
PMID: 26807725
Journal: Cell Stem Cell. 2016 Aug 4;19(2):205-216.
Title: Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
Author: Dominguez-Brauer, Carmen|Hao, Zhenyue|Elia, Andrew J|Fortin, Jerome M|Nechanitzky, Robert|Brauer, Patrick M|Sheng, Yi|Mana, Miyeko D|Chio, Iok In Christine|Haight, Jillian|Pollett, Aaron|Cairns, Robert|Tworzyanski, Leanne|Inoue, Satoshi|Reardon, Colin|Mar
PMID: 27184401
Journal: Sci Rep. 2016 Jun 23;6:28299.
Title: TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3.
Author: Murphy, Matthew|Chatterjee, Sujash S|Jain, Sidharth|Katari, Manpreet|DasGupta, Ramanuj
PMID: 27333864
Journal: Cancer Sci. 2017 Mar;108(3):408-418.
Title: EphB3-targeted regulation of miR-149 in the migration and invasion of human colonic carcinoma HCT116 and SW620 cells.
Author: Zhang, Guodong|Liu, Xiaozhu|Li, Yinfeng|Wang, Yan|Liang, Huankun|Li, Kangyan|Li, Laiqing|Chen, Cuicui|Sun, Wenqiao|Ren, Shoulei|Zhu, Pengfei|Zhang, Licheng
PMID: 28370854
Journal: PLoS Genet. 2017 Nov 20;13(11):e1007109.
Title: SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.
Author: Jagle, Sabine|Busch, Hauke|Freihen, Vivien|Beyes, Sven|Schrempp, Monika|Boerries, Melanie|Hecht, Andreas
PMID: 29155818
Journal: Mol Med Rep. 2018 Jun;17(6):7721-7729.
Title: Formononetin inhibits colon carcinoma cell growth and invasion by microRNA149mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Author: Wang, Ai-Lei|Li, Yong|Zhao, Qun|Fan, Li-Qiao
PMID: 29620230