Primary Site >> Colorectal Cancer

Gene >> EPHB3

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Ref: Coexpression of ephrin-Bs and their receptors in colon carcinoma.
PMID: 11920461
Ref: Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.
PMID: 12408869
Ref: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
PMID: 17906625
Ref: The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers.
PMID: 18281782
Ref: Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.
PMID: 19483190
Ref: The role of Eph receptors and ephrin ligands in colorectal cancer.
PMID: 20039322
Ref: Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.
PMID: 20479215
Ref: EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration.
PMID: 21266352
Ref: A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer.
PMID: 21352556
Ref: Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer.
PMID: 21393996
Ref: Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.
PMID: 24707046
Ref: SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
PMID: 25277775
Ref: Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.
PMID: 26807725
Ref: Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
PMID: 27184401
Ref: TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3.
PMID: 27333864
Ref: EphB3-targeted regulation of miR-149 in the migration and invasion of human colonic carcinoma HCT116 and SW620 cells.
PMID: 28370854
Ref: SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.
PMID: 29155818
Ref: Formononetin inhibits colon carcinoma cell growth and invasion by microRNA149mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
PMID: 29620230