Literatures

Primary Site >> Pancreatic Cancer

Gene >> EPHB2

1.
Journal:	Oncogene. 1999 Apr 22;18(16):2579-88.
Title:	A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice.
Author:	Weisz, B\|Giehl, K\|Gana-Weisz, M\|Egozi, Y\|Ben-Baruch, G\|Marciano, D\|Gierschik, P\|Kloog, Y
PMID:	10353601

2.
Journal:	Int J Oncol. 1999 Aug;15(2):271-9.
Title:	Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression.
Author:	Yip-Schneider, M T\|Lin, A\|Barnard, D\|Sweeney, C J\|Marshall, M S
PMID:	10402237

3.
Journal:	J Gastroenterol. 2000;35(1):1-9.
Title:	Stress kinases and heat shock proteins in the pancreas: possible roles in normal function and disease.
Author:	Schafer, C\|Williams, J A
PMID:	10632533

4.
Journal:	Biochem Biophys Res Commun. 2000 Mar 24;269(3):704-8.
Title:	Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2.
Author:	Ehlers, R A\|Zhang, Y\|Hellmich, M R\|Evers, B M
PMID:	10720480

5.
Journal:	Oncogene. 2000 Sep 14;19(39):4531-41.
Title:	TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation.
Author:	Giehl, K\|Seidel, B\|Gierschik, P\|Adler, G\|Menke, A
PMID:	11002426

6.
Journal:	Genes Dev. 2001 Feb 1;15(3):286-93.
Title:	A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease.
Author:	Wagner, M\|Greten, F R\|Weber, C K\|Koschnick, S\|Mattfeldt, T\|Deppert, W\|Kern, H\|Adler, G\|Schmid, R M
PMID:	11159909

7.
Journal:	Biochem Biophys Res Commun. 2001 Feb 2;280(4):992-7.
Title:	Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.
Author:	Yip-Schneider, M T\|Lin, A\|Marshall, M S
PMID:	11162624

8.
Journal:	Biochem Biophys Res Commun. 2001 Mar 30;282(2):447-53.
Title:	MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1.
Author:	Ding, X Z\|Adrian, T E
PMID:	11401480

9.
Journal:	Biochem Biophys Res Commun. 2001 Jul 13;285(2):207-16.
Title:	cAMP protection of pancreatic cancer cells against apoptosis induced by ERK inhibition.
Author:	Boucher, M J\|Duchesne, C\|Laine, J\|Morisset, J\|Rivard, N
PMID:	11444827

10.
Journal:	Gastroenterology. 2001 Sep;121(3):657-67.
Title:	Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines.
Author:	Weber, C K\|Sommer, G\|Michl, P\|Fensterer, H\|Weimer, M\|Gansauge, F\|Leder, G\|Adler, G\|Gress, T M
PMID:	11522750

11.
Journal:	Pancreas. 2001 Oct;23(3):236-45.
Title:	Integrin-mediated differentiation of a pancreatic carcinoma cell line is independent of FAK or MAPK activation levels.
Author:	Stagge, V\|Seufferlein, T\|Duerschmied, D\|Menke, A\|Adler, G\|Beil, M
PMID:	11590318

12.
Journal:	Int J Cancer. 2001 Dec 1;94(5):630-6.
Title:	12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation.
Author:	Ding, X Z\|Tong, W G\|Adrian, T E
PMID:	11745456

13.
Journal:	Anticancer Res. 2002 Mar-Apr;22(2A):559-64.
Title:	Irofulven (6-hydroxymethylacylfulvene, MGI 114)-induced apoptosis in human pancreatic cancer cells is mediated by ERK and JNK kinases.
Author:	Wang, Weixin\|Waters, Stephen J\|MacDonald, John R\|Roth, Caleb\|Shentu, Shujun\|Freeman, James\|Von Hoff, Daniel D\|Miller, Alexander R
PMID:	12014623

14.
Journal:	FASEB J. 2002 Jul;16(9):975-82.
Title:	Heterotopic implantation alters the regulation of apoptosis and the cell cycle and generates a new metastatic site in a human pancreatic tumor xenograft model.
Author:	Farre, Lourdes\|Casanova, Isolda\|Guerrero, Silvia\|Trias, Manuel\|Capella, Gabriel\|Mangues, Ramon
PMID:	12087058

15.
Journal:	Oncogene. 2002 Aug 29;21(38):5923-8.
Title:	Dominant negative MEKK1 inhibits survival of pancreatic cancer cells.
Author:	Hirano, Tatsuya\|Shino, Yuji\|Saito, Takeshi\|Komoda, Fumitake\|Okutomi, Yoshiyuki\|Takeda, Akiko\|Ishihara, Takeshi\|Yamaguchi, Taketo\|Saisho, Hiromitsu\|Shirasawa, Hiroshi
PMID:	12185592

16.
Journal:	Int J Gastrointest Cancer. 2002;31(1-3):15-21.
Title:	Novel protein kinases in pancreatic cell growth and cancer.
Author:	Seufferlein, Thomas
PMID:	12622411

17.
Journal:	Int J Cancer. 2003 Jul 1;105(4):454-8.
Title:	Leucine-zipper protein, LDOC1, inhibits NF-kappaB activation and sensitizes pancreatic cancer cells to apoptosis.
Author:	Nagasaki, Koichi\|Schem, Christian\|von Kaisenberg, Constantin\|Biallek, Marco\|Rosel, Frank\|Jonat, Walter\|Maass, Nicolai
PMID:	12712434

18.
Journal:	Cancer Res. 2003 May 15;63(10):2379-87.
Title:	Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.
Author:	Guha, Sushovan\|Lunn, J Adrian\|Santiskulvong, Chintda\|Rozengurt, Enrique
PMID:	12750255

19.
Journal:	Am J Pathol. 2003 Jun;162(6):1807-15.
Title:	Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer.
Author:	Furukawa, Toru\|Sunamura, Makoto\|Motoi, Fuyuhiko\|Matsuno, Seiki\|Horii, Akira
PMID:	12759238

20.
Journal:	Br J Cancer. 2003 Jun 16;88(12):1971-8.
Title:	Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.
Author:	Tassone, P\|Tagliaferri, P\|Viscomi, C\|Palmieri, C\|Caraglia, M\|D'Alessandro, A\|Galea, E\|Goel, A\|Abbruzzese, A\|Boland, C R\|Venuta, S
PMID:	12799645

21.
Journal:	J Cell Sci. 2003 Sep 15;116(Pt 18):3835-46. Epub 2003 Aug 5.
Title:	Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.
Author:	Stahle, Martina\|Veit, Christine\|Bachfischer, Ulla\|Schierling, Karina\|Skripczynski, Bettina\|Hall, Alan\|Gierschik, Peter\|Giehl, Klaudia
PMID:	12902401

22.
Journal:	Cancer. 2003 Aug 15;98(4):720-9.
Title:	Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma.
Author:	Parikh, Alexander A\|Liu, Wen Biao\|Fan, Fan\|Stoeltzing, Oliver\|Reinmuth, Niels\|Bruns, Christiane J\|Bucana, Corazon D\|Evans, Douglas B\|Ellis, Lee M
PMID:	12910515

23.
Journal:	Semin Oncol. 2003 Oct;30(5 Suppl 16):105-16.
Title:	CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK).
Author:	Allen, Lee F\|Sebolt-Leopold, Judith\|Meyer, Mark B
PMID:	14613031

24.
Journal:	Mol Cancer. 2003 Nov 5;2:37.
Title:	p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.
Author:	Malicet, Cedric\|Lesavre, Nathalie\|Vasseur, Sophie\|Iovanna, Juan L
PMID:	14613582

25.
Journal:	Oncology. 2003;65(4):285-94.
Title:	Multiple signal pathways are involved in the mitogenic effect of 5(S)-HETE in human pancreatic cancer.
Author:	Ding, Xian-Zhong\|Tong, Wei-Gang\|Adrian, Thomas E
PMID:	14707447

26.
Journal:	Cancer Res Treat. 2003 Jun;35(3):207-12.
Title:	Invasion-Metastasis by Hepatocyte Growth Factor/c-Met Signaling Concomitant with Induction of Urokinase Plasminogen Activator in Human Pancreatic Cancer: Role as Therapeutic Target.
Author:	Lee, Kyung Hee\|Hyun, Myung Soo\|Kim, Jae Ryong
PMID:	26680937

27.
Journal:	Genes Chromosomes Cancer. 2004 Mar;39(3):224-35.
Title:	Expression profiling of the influence of RAS mutants on the TGFB1-induced phenotype of the pancreatic cancer cell line PANC-1.
Author:	Fensterer, Heiko\|Giehl, Klaudia\|Buchholz, Malte\|Ellenrieder, Volker\|Buck, Anita\|Kestler, Hans A\|Adler, Guido\|Gierschik, Peter\|Gress, Thomas M
PMID:	14732924

28.
Journal:	Biochem Biophys Res Commun. 2004 Mar 26;316(1):71-7.
Title:	Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells.
Author:	Habiro, Atsuya\|Tanno, Satoshi\|Koizumi, Kazuya\|Izawa, Tsutomu\|Nakano, Yasuhiro\|Osanai, Manabu\|Mizukami, Yusuke\|Okumura, Toshikatsu\|Kohgo, Yutaka
PMID:	15003513

29.
Journal:	Pancreas. 2004 Mar;28(2):153-9.
Title:	Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2.
Author:	Hashimoto, Koji\|Farrow, Buckminster J\|Evers, B Mark
PMID:	15028947

30.
Journal:	Clin Cancer Res. 2004 Apr 1;10(7):2299-306.
Title:	Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
Author:	Yokoi, Kenji\|Fidler, Isaiah J
PMID:	15073105

31.
Journal:	Gastroenterology. 2004 Aug;127(2):607-20.
Title:	KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells.
Author:	Ellenrieder, Volker\|Buck, Anita\|Harth, Ana\|Jungert, Kerstin\|Buchholz, Malte\|Adler, Guido\|Urrutia, Raul\|Gress, Thomas M
PMID:	15300592

32.
Journal:	Cancer Chemother Pharmacol. 2004 Sep;54 Suppl 1:S69-77.
Title:	Molecular targeting therapy for pancreatic cancer.
Author:	Xiong, Henry Q
PMID:	15316751

33.
Journal:	Cancer Res. 2005 Apr 1;65(7):2861-71.
Title:	Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
Author:	Venkatasubbarao, Kolaparthi\|Choudary, Ahsan\|Freeman, James W
PMID:	15805288

34.
Journal:	Mol Cancer. 2005 Jun 21;4(1):21.
Title:	Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1.
Author:	Lin, Min\|DiVito, Melinda M\|Merajver, Sofia D\|Boyanapalli, Madanamohan\|van Golen, Kenneth L
PMID:	15969750

35.
Journal:	Biochem Biophys Res Commun. 2005 Sep 30;335(3):949-56.
Title:	LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways.
Author:	Tong, Wei-Gang\|Ding, Xian-Zhong\|Talamonti, Mark S\|Bell, Richard H\|Adrian, Thomas E
PMID:	16105664

36.
Journal:	J Clin Pathol. 2005 Dec;58(12):1242-8.
Title:	Involvement of MMP-7 in invasion of pancreatic cancer cells through activation of the EGFR mediated MEK-ERK signal transduction pathway.
Author:	Tan, X\|Egami, H\|Abe, M\|Nozawa, F\|Hirota, M\|Ogawa, M
PMID:	16311341

37.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G729-36.
Title:	Galectin-1 induces chemokine production and proliferation in pancreatic stellate cells.
Author:	Masamune, Atsushi\|Satoh, Masahiro\|Hirabayashi, Jun\|Kasai, Kenichi\|Satoh, Kennichi\|Shimosegawa, Tooru
PMID:	16373424

38.
Journal:	Am J Pathol. 2006 Mar;168(3):962-72.
Title:	Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.
Author:	Trevino, Jose G\|Summy, Justin M\|Lesslie, Donald P\|Parikh, Nila U\|Hong, David S\|Lee, Francis Y\|Donato, Nicholas J\|Abbruzzese, James L\|Baker, Cheryl H\|Gallick, Gary E
PMID:	16507911

39.
Journal:	Int J Oncol. 2006 Jul;29(1):33-40.
Title:	MUC5AC mucin gene regulation in pancreatic cancer cells.
Author:	Kato, Shingo\|Hokari, Ryota\|Crawley, Suzanne\|Gum, James\|Ahn, Dae-Ho\|Kim, Jong-Woo\|Kwon, Sung-Won\|Miura, Soichiro\|Basbaum, Carol B\|Kim, Young S
PMID:	16773182

40.
Journal:	Ann Surg Oncol. 2006 Jul;13(7):933-9. Epub 2006 May 22.
Title:	Activated Akt and Erk expression and survival after surgery in pancreatic carcinoma.
Author:	Chadha, Krishdeep S\|Khoury, Thaer\|Yu, Jihnhee\|Black, Jennifer D\|Gibbs, John F\|Kuvshinoff, Boris W\|Tan, Dongfeng\|Brattain, Michael G\|Javle, Milind M
PMID:	16788754

41.
Journal:	World J Gastroenterol. 2006 Jul 28;12(28):4498-503.
Title:	Mechanism for Src activation by the CCK2 receptor: Patho-physiological functions of this receptor in pancreas.
Author:	Ferrand, Audrey\|Vatinel, Sebastien\|Kowalski-Chauvel, Aline\|Bertrand, Claudine\|Escrieut, Chantal\|Fourmy, Daniel\|Dufresne, Marlene\|Seva, Catherine
PMID:	16874861

42.
Journal:	Oncol Rep. 2006 Oct;16(4):907-13.
Title:	Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells.
Author:	Qiu, Lihua\|Zhou, Changlin\|Sun, Yun\|Di, Wen\|Scheffler, Erica\|Healey, Sarah\|Wanebo, Harold\|Kouttab, Nicola\|Chu, Wenming\|Wan, Yinsheng
PMID:	16969513

43.
Journal:	Int J Gastrointest Cancer. 2006;37(4):110-9.
Title:	Characterization of the CXCR4 signaling in pancreatic cancer cells.
Author:	Billadeau, Daniel D\|Chatterjee, Subrha\|Bramati, Patricia\|Sreekumar, Raghavakaimal\|Shah, Vijay\|Hedin, Karen\|Urrutia, Raul
PMID:	18175225

44.
Journal:	Cancer Lett. 2007 May 8;249(2):242-8.
Title:	BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas.
Author:	Schonleben, Frank\|Qiu, Wanglong\|Bruckman, Karl C\|Ciau, Nancy T\|Li, Xiaojun\|Lauerman, Margaret H\|Frucht, Harold\|Chabot, John A\|Allendorf, John D\|Remotti, Helen E\|Su, Gloria H
PMID:	17097223

45.
Journal:	Cancer. 2007 Mar 15;109(6):1030-9.
Title:	Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target.
Author:	Camp, E Ramsay\|Yang, Anthony\|Gray, Mike J\|Fan, Fan\|Hamilton, Stanley R\|Evans, Douglas B\|Hooper, Andrea T\|Pereira, Daniel S\|Hicklin, Daniel J\|Ellis, Lee M
PMID:	17311308

46.
Journal:	Cancer Biol Ther. 2007 Mar;6(3):367-76. Epub 2007 Mar 13.
Title:	Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.
Author:	Kusumawidjaja, Grace\|Kayed, Hany\|Giese, Nathalia\|Bauer, Andrea\|Erkan, Mert\|Giese, Thomas\|Hoheise, Jorg D\|Friess, Helmut\|Kleeff, Jorg
PMID:	17312387

47.
Journal:	Ann Surg Oncol. 2007 Jul;14(7):2150-8. Epub 2007 Apr 24.
Title:	Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response.
Author:	Tzeng, Ching-Wei D\|Frolov, Andrey\|Frolova, Natalya\|Jhala, Nirag C\|Howard, J Harrison\|Vickers, Selwyn M\|Buchsbaum, Donald J\|Heslin, Martin J\|Arnoletti, J Pablo
PMID:	17453292

48.
Journal:	Front Biosci. 2007 Sep 1;12:5039-51.
Title:	Epigallocatechin-3-gallate inhibits cell cycle and induces apoptosis in pancreatic cancer.
Author:	Shankar, Sharmila\|Suthakar, Ganapathy\|Srivastava, Rakesh K
PMID:	17569628

49.
Journal:	Cancer Lett. 2007 Oct 8;255(2):241-54. Epub 2007 Jun 21.
Title:	Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies.
Author:	Katzav, Shulamit
PMID:	17590270

50.
Journal:	Carcinogenesis. 2007 Nov;28(11):2321-7. Epub 2007 Jul 17.
Title:	RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells.
Author:	Chow, Jimmy Y C\|Quach, Khai T\|Cabrera, Betty L\|Cabral, Jennifer A\|Beck, Stayce E\|Carethers, John M
PMID:	17638924

51.
Journal:	Cell Oncol. 2007;29(4):315-26.
Title:	Neurotensin is a versatile modulator of in vitro human pancreatic ductal adenocarcinoma cell (PDAC) migration.
Author:	Mijatovic, Tatjana\|Gailly, Philippe\|Mathieu, Veronique\|De Neve, Nancy\|Yeaton, Paul\|Kiss, Robert\|Decaestecker, Christine
PMID:	17641415

52.
Journal:	Cancer Res. 2007 Aug 1;67(15):7266-74.
Title:	Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.
Author:	Rengifo-Cam, William\|Umar, Shahid\|Sarkar, Shubhashish\|Singh, Pomila
PMID:	17671195

53.
Journal:	Int J Oncol. 2007 Oct;31(4):693-703.
Title:	Expression of connective tissue growth factor in pancreatic cancer cell lines.
Author:	Kwon, Sungwon\|Munroe, Xander\|Crawley, Suzanne C\|Lee, Hwa Young\|Spong, Suzanne\|Bradham, Douglass\|Gum, James R Jr\|Sleisenger, Marvin H\|Kim, Young S
PMID:	17786299

54.
Journal:	Ann Surg Oncol. 2007 Dec;14(12):3527-33.
Title:	Epithelial-mesenchymal transition (EMT) and activated extracellular signal-regulated kinase (p-Erk) in surgically resected pancreatic cancer.
Author:	Javle, M M\|Gibbs, J F\|Iwata, K K\|Pak, Y\|Rutledge, P\|Yu, J\|Black, J D\|Tan, D\|Khoury, T
PMID:	17879119

55.
Journal:	Cancer Res. 2007 Oct 15;67(20):9704-12.
Title:	Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
Author:	Takehara, Akio\|Hosokawa, Masayo\|Eguchi, Hidetoshi\|Ohigashi, Hiroaki\|Ishikawa, Osamu\|Nakamura, Yusuke\|Nakagawa, Hidewaki
PMID:	17942900

56.
Journal:	J Surg Res. 2007 Nov;143(1):20-6.
Title:	EGFR genomic gain and aberrant pathway signaling in pancreatic cancer patients.
Author:	Tzeng, Ching-Wei D\|Frolov, Andrey\|Frolova, Natalya\|Jhala, Nirag C\|Howard, J Harrison\|Vickers, Selwyn M\|Buchsbaum, Donald J\|Heslin, Martin J\|Arnoletti, J Pablo
PMID:	17950068

57.
Journal:	Cancer Lett. 2007 Dec 18;258(2):291-300.
Title:	Regulation of cyclooxygenase-2 (COX-2) expression in human pancreatic carcinoma cells by the insulin-like growth factor-I receptor (IGF-IR) system.
Author:	Stoeltzing, Oliver\|Liu, Wenbiao\|Fan, Fan\|Wagner, Christine\|Stengel, Kathrin\|Somcio, Ray J\|Reinmuth, Niels\|Parikh, Alexander A\|Hicklin, Daniel J\|Ellis, Lee M
PMID:	17950526

58.
Journal:	Clin Cancer Res. 2007 Nov 1;13(21):6459-68.
Title:	Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotop
Author:	Lang, Sven A\|Moser, Christian\|Gaumann, Andreas\|Klein, Dagmar\|Glockzin, Gabriel\|Popp, Felix C\|Dahlke, Marc H\|Piso, Pompiliu\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	17975158

59.
Journal:	J Cell Commun Signal. 2007 Sep;1(2):85-90.
Title:	Analysis of CCN2 promoter activity in PANC-1 cells: regulation by ras/MEK/ERK.
Author:	Pickles, Melissa\|Leask, Andrew
PMID:	18481199

60.
Journal:	Front Biosci. 2008 Jan 1;13:440-52.
Title:	EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.
Author:	Shankar, Sharmila\|Ganapathy, Suthakar\|Hingorani, Sunil R\|Srivastava, Rakesh K
PMID:	17981559

61.
Journal:	Cancer. 2008 Feb 15;112(4):767-78.
Title:	GABA B receptor is a novel drug target for pancreatic cancer.
Author:	Schuller, Hildegard M\|Al-Wadei, Hussein A N\|Majidi, Mourad
PMID:	18098271

62.
Journal:	BMC Cancer. 2008 Feb 6;8:43.
Title:	Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis.
Author:	Pham, Nhu-An\|Schwock, Joerg\|Iakovlev, Vladimir\|Pond, Greg\|Hedley, David W\|Tsao, Ming-Sound
PMID:	18254976

63.
Journal:
Title:	Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer.
Author:
PMID:	18307536

64.
Journal:	Ann Clin Lab Sci. 2008 Winter;38(1):47-56.
Title:	Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase.
Author:	Adler, Victor\|Bowne, Wilbur\|Michl, Josef\|Sookraj, Kelley A\|Ikram, Kamran\|Pestka, Sidney\|Izotova, Lara\|Zenilman, Michael\|Friedman, Fred K\|Qu, Yongxia\|Pincus, Matthew R
PMID:	18316782

65.
Journal:	Langenbecks Arch Surg. 2008 May;393(3):289-96.
Title:	PIK3CA, KRAS, and BRAF mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/C) of the pancreas.
Author:	Schonleben, Frank\|Qiu, Wanglong\|Remotti, Helen E\|Hohenberger, Werner\|Su, Gloria H
PMID:	18343945

66.
Journal:	Blood. 2008 May 15;111(10):5054-63.
Title:	Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3.
Author:	Chang, Yung-Chi\|Chen, Tse-Ching\|Lee, Chun-Ting\|Yang, Chih-Ya\|Wang, Hsei-Wei\|Wang, Chao-Ching\|Hsieh, Shie-Liang
PMID:	18349319

67.
Journal:	Methods Enzymol. 2008;439:451-65.
Title:	Ras-driven transformation of human nestin-positive pancreatic epithelial cells.
Author:	Campbell, Paul M\|Lee, Kwang M\|Ouellette, Michel M\|Kim, Hong Jin\|Groehler, Angela L\|Khazak, Vladimir\|Der, Channing J
PMID:	18374182

68.
Journal:	Curr Med Chem. 2008;15(10):978-90.
Title:	ANTI-ADHESION evolves to a promising therapeutic concept in oncology.
Author:	Schmidmaier, R\|Baumann, P
PMID:	18393855

69.
Journal:	Eur J Cancer. 2008 Jul;44(11):1577-86.
Title:	Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis.
Author:	Moser, Christian\|Schachtschneider, Philipp\|Lang, Sven A\|Gaumann, Andreas\|Mori, Akira\|Zimmermann, Johann\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	18445520

70.
Journal:	Int J Radiat Oncol Biol Phys. 2008 Jul 1;71(3):873-9.
Title:	SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation.
Author:	Cuneo, Kyle C\|Geng, Ling\|Fu, Allie\|Orton, Darren\|Hallahan, Dennis E\|Chakravarthy, Anuradha Bapsi
PMID:	18514780

71.
Journal:	Am J Physiol Cell Physiol. 2008 Aug;295(2):C394-405.
Title:	Erythropoietin enhancement of rat pancreatic tumor cell proliferation requires the activation of ERK and JNK signals.
Author:	Bose, Chhanda\|Udupa, Kodetthoor B
PMID:	18550701

72.
Journal:	BMC Cancer. 2008 Oct 10;8:294.
Title:	Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis.
Author:	Shi, Yan\|Sahu, Ravi P\|Srivastava, Sanjay K
PMID:	18847491

73.
Journal:	Mol Cancer Ther. 2008 Nov;7(11):3509-18.
Title:	Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes.
Author:	Lang, Sven A\|Schachtschneider, Philipp\|Moser, Christian\|Mori, Akira\|Hackl, Christina\|Gaumann, Andreas\|Batt, David\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	19001434

74.
Journal:	Expert Rev Gastroenterol Hepatol. 2008 Oct;2(5):673-96.
Title:	New treatment options for advanced pancreatic cancer.
Author:	Middleton, Gary\|Ghaneh, Paula\|Costello, Eithne\|Greenhalf, William\|Neoptolemos, John P
PMID:	19072345

75.
Journal:	Cancer Lett. 2009 Jan 18;273(2):292-9.
Title:	Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling.
Author:	Zhou, Hui\|Huang, Liqun\|Sun, Yu\|Rigas, Basil
PMID:	18805632

76.
Journal:	J Cell Commun Signal. 2009 Jun;3(2):159-60.
Title:	Death of a tumor: targeting CCN in pancreatic cancer.
Author:	Leask, Andrew
PMID:	19267221

77.
Journal:	Biochem Biophys Res Commun. 2009 Mar 13;380(3):614-9.
Title:	Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells.
Author:	Kumei, Shima\|Motomura, Wataru\|Yoshizaki, Takayuki\|Takakusaki, Kaoru\|Okumura, Toshikatsu
PMID:	19285010

78.
Journal:	J Cell Physiol. 2009 Jul;220(1):214-21.
Title:	Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
Author:	Ulivi, Paola\|Arienti, Chiara\|Amadori, Dino\|Fabbri, Francesco\|Carloni, Silvia\|Tesei, Anna\|Vannini, Ivan\|Silvestrini, Rosella\|Zoli, Wainer
PMID:	19288493

79.
Journal:	Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1731-8.
Title:	Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling.
Author:	Xue, Aiqun\|Xue, Meilang\|Jackson, Christopher\|Smith, Ross C
PMID:	19433314

80.
Journal:	J Cancer Res Clin Oncol. 2009 Dec;135(12):1655-63.
Title:	Depleting MEKK1 expression inhibits the ability of invasion and migration of human pancreatic cancer cells.
Author:	Su, Fuqin\|Li, Hongyan\|Yan, Chaoqi\|Jia, Baoqing\|Zhang, Yi\|Chen, Xiaoguang
PMID:	19513748

81.
Journal:	Anticancer Agents Med Chem. 2009 Oct;9(8):877-81.
Title:	A novel strategy for advanced pancreatic cancer - progression of molecular targeting therapy.
Author:	Osada, Shinji\|Yoshida, Kazuhiro
PMID:	19538163

82.
Journal:	Carcinogenesis. 2009 Oct;30(10):1744-53.
Title:	Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.
Author:	Sahu, Ravi P\|Zhang, Ruifen\|Batra, Sanjay\|Shi, Yan\|Srivastava, Sanjay K
PMID:	19549704

83.
Journal:	Yao Xue Xue Bao. 2009 May;44(5):456-61.
Title:	[Effect of icogenin on and its mechanism in anti-metastasis of pancreatic cancer BxPC3 cells].
Author:	Su, Fu-qin\|Li, Hong-yan\|Zhang, Yi\|Hou, Shu-jie\|Lei, Ping-sheng\|Chen, Xiao-guang
PMID:	19618718

84.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1390-8.
Title:	Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha.
Author:	Mori, Akira\|Moser, Christian\|Lang, Sven A\|Hackl, Christina\|Gottfried, Eva\|Kreutz, Marina\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	19671674

85.
Journal:	Cancer Biol Ther. 2009 Oct;8(20):1893-901. Epub 2009 Oct 6.
Title:	Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models.
Author:	Chang, Qing\|Chen, Eric\|Hedley, David W
PMID:	20009539

86.
Journal:	Zhonghua Zhong Liu Za Zhi. 2009 Oct;31(10):732-7.
Title:	[Over-expression of caveolin-1 inhibits proliferation and invasion of pancreatic carcinoma cells in vitro].
Author:	Han, Fei\|Zhu, Hong-guang
PMID:	20021823

87.
Journal:	Pancreas. 2010 Jan;39(1):81-7.
Title:	Chemokine receptor CXCR4 enhances proliferation in pancreatic cancer cells through AKT and ERK dependent pathways.
Author:	Shen, Xiaoming\|Artinyan, Avo\|Jackson, Desmond\|Thomas, Ryan M\|Lowy, Andrew M\|Kim, Joseph
PMID:	19820417

88.
Journal:	Pancreas. 2010 Apr;39(3):332-9.
Title:	Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors.
Author:	Pham, Hung\|Chen, Monica\|Li, Aihua\|King, Jonathan\|Angst, Eliane\|Dawson, David W\|Park, Jenny\|Reber, Howard A\|Hines, O Joe\|Eibl, Guido
PMID:	19820419

89.
Journal:	J Surg Res. 2010 Mar;159(1):443-50.
Title:	Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells.
Author:	Han, Fei\|Zhu, Hong-Guang
PMID:	20031158

90.
Journal:	Oncogene. 2010 May 27;29(21):3146-52.
Title:	Activation of EGFR by proteasome inhibition requires HB-EGF in pancreatic cancer cells.
Author:	Sloss, C M\|Wang, F\|Palladino, M A\|Cusack, J C Jr
PMID:	20208558

91.
Journal:	J Cell Physiol. 2010 Jul;224(1):112-9.
Title:	Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.
Author:	Wei, Gang\|Wang, Meifang\|Carr, Brian I
PMID:	20301194

92.
Journal:	Cancer Sci. 2010 May;101(5):1226-33.
Title:	Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis.
Author:	Li, Wei\|Xie, Li\|Chen, Zheng\|Zhu, Yi\|Sun, Yujie\|Miao, Yi\|Xu, Zekuan\|Han, Xiao
PMID:	20331621

93.
Journal:	World J Gastroenterol. 2010 Apr 28;16(16):1970-8.
Title:	Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells.
Author:	Emonds, Elisabeth\|Fitzner, Brit\|Jaster, Robert
PMID:	20419833

94.
Journal:	Curr Cancer Drug Targets. 2010 Sep;10(6):600-10.
Title:	In vitro and in vivo antitumor efficacy of docetaxel and sorafenib combination in human pancreatic cancer cells.
Author:	Ulivi, P\|Arienti, C\|Zoli, W\|Scarsella, M\|Carloni, S\|Fabbri, F\|Tesei, A\|Chiadini, E\|Orlandi, A\|Passeri, D\|Zupi, G\|Milandri, C\|Silvestrini, R\|Amadori, D\|Leonetti, C
PMID:	20491617

95.
Journal:	Ann Surg Oncol. 2010 Oct;17(10):2619-27.
Title:	Higher expression of the heterogeneous nuclear ribonucleoprotein k in melanoma.
Author:	Wen, Fushi\|Shen, Alex\|Shanas, Renee\|Bhattacharyya, Achyut\|Lian, Fangru\|Hostetter, Galen\|Shi, Jiaqi
PMID:	20499280

96.
Journal:	Oncogene. 2010 Sep 16;29(37):5146-58.
Title:	AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-beta-mediated ERK signaling.
Author:	Kong, B\|Michalski, C W\|Hong, X\|Valkovskaya, N\|Rieder, S\|Abiatari, I\|Streit, S\|Erkan, M\|Esposito, I\|Friess, H\|Kleeff, J
PMID:	20581862

97.
Journal:	BMC Cancer. 2010 Jul 14;10:368.
Title:	Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.
Author:	Javle, Milind M\|Shroff, Rachna T\|Xiong, Henry\|Varadhachary, Gauri A\|Fogelman, David\|Reddy, Shrikanth A\|Davis, Darren\|Zhang, Yujian\|Wolff, Robert A\|Abbruzzese, James L
PMID:	20630061

98.
Journal:	Gynecol Oncol. 2010 Oct;119(1):146-50.
Title:	Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.
Author:	Chiappinelli, Katherine B\|Rimel, B J\|Massad, L Stewart\|Goodfellow, Paul J
PMID:	20638106

99.
Journal:	J Mol Signal. 2010 Jul 19;5:10.
Title:	Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.
Author:	Roy, Sanjit K\|Srivastava, Rakesh K\|Shankar, Sharmila
PMID:	20642839

100.
Journal:	Mol Pharm. 2010 Oct 4;7(5):1576-84.
Title:	MEK inhibition potentiates the activity of Hsp90 inhibitor 17-AAG against pancreatic cancer cells.
Author:	Zhang, Tao\|Li, Yanyan\|Zhu, Zhenkun\|Gu, Mancang\|Newman, Bryan\|Sun, Duxin
PMID:	20669973

101.
Journal:	Chemotherapy. 2010;56(4):303-12.
Title:	Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells.
Author:	Ricciardi, Simona\|Mey, Valentina\|Nannizzi, Sara\|Pasqualetti, Giuseppe\|Crea, Francesco\|Del Tacca, Mario\|Danesi, Romano
PMID:	20714148

102.
Journal:	J Cell Biochem. 2010 Dec 1;111(5):1160-8.
Title:	Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Author:	Min, Chengyin\|Zhao, Yingshe\|Romagnoli, Mathilde\|Trackman, Philip C\|Sonenshein, Gail E\|Kirsch, Kathrin H
PMID:	20717927

103.
Journal:	Cancer Sci. 2010 Nov;101(11):2351-60.
Title:	Amphiregulin regulates the activation of ERK and Akt through epidermal growth factor receptor and HER3 signals involved in the progression of pancreatic cancer.
Author:	Yotsumoto, Fusanori\|Fukami, Tatsuya\|Yagi, Hiroshi\|Funakoshi, Akihiro\|Yoshizato, Toshiyuki\|Kuroki, Masahide\|Miyamoto, Shingo
PMID:	20726858

104.
Journal:	PLoS One. 2010 Sep 8;5(9):e12653.
Title:	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.
Author:	Corbo, Vincenzo\|Ritelli, Rossana\|Barbi, Stefano\|Funel, Niccola\|Campani, Daniela\|Bardelli, Alberto\|Scarpa, Aldo
PMID:	20838624

105.
Journal:	Mol Cancer. 2010 Sep 21;9:253.
Title:	Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway.
Author:	Cubas, Rafael\|Zhang, Sheng\|Li, Min\|Chen, Changyi\|Yao, Qizhi
PMID:	20858281

106.
Journal:	Cancer Biol Ther. 2010 Nov 15;10(10):1056-66.
Title:	The induction of S100p expression by the Prostaglandin E(2) (PGE(2))/EP4 receptor signaling pathway in colon cancer cells.
Author:	Chandramouli, Anupama\|Mercado-Pimentel, Melania E\|Hutchinson, Anthony\|Gibadulinova, Adriana\|Olson, Erik R\|Dickinson, Sally\|Shanas, Renee\|Davenport, Jennifer\|Owens, Janae\|Bhattacharyya, Achyut K\|Regan, John W\|Pastorekova, Silvia\|Arumugam, Thiruvengadam\|Log
PMID:	20890108

107.
Journal:	BMC Cancer. 2010 Sep 28;10:515.
Title:	Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts.
Author:	Chang, Qing\|Chapman, Mark S\|Miner, Jeffrey N\|Hedley, David W
PMID:	20920162

108.
Journal:	Gut. 2010 Nov;59(11):1535-44.
Title:	PRSS3 promotes tumour growth and metastasis of human pancreatic cancer.
Author:	Jiang, Guozhong\|Cao, Fengyu\|Ren, Guoping\|Gao, Dongling\|Bhakta, Vipul\|Zhang, Yunhan\|Cao, Hua\|Dong, Ziming\|Zang, Weidong\|Zhang, Shuijun\|Wong, Han Hsi\|Hiley, Crispin\|Crnogorac-Jurcevic, Tatjana\|Lemoine, Nick R\|Wang, Yaohe
PMID:	20947888

109.
Journal:	J Mol Signal. 2010 Nov 2;5:18.
Title:	TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling.
Author:	Campbell, Paul M\|Boufaied, Nadia\|Fiordalisi, James J\|Cox, Adrienne D\|Falardeau, Pierre\|Der, Channing J\|Gourdeau, Henriette
PMID:	21044336

110.
Journal:	Br J Cancer. 2010 Nov 23;103(11):1671-9.
Title:	CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy.
Author:	Singh, S\|Srivastava, S K\|Bhardwaj, A\|Owen, L B\|Singh, A P
PMID:	21045835

111.
Journal:	Cancer Chemother Pharmacol. 2011 Aug;68(2):477-87.
Title:	Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells.
Author:	Messner, Maria C\|Cabot, Myles C
PMID:	21072519

112.
Journal:	Exp Mol Med. 2011 Feb 28;43(2):82-90.
Title:	Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of beta-catenin, leading to a rapid proliferation of pancreatic cells.
Author:	Cho, Il-Rae\|Koh, Sang Seok\|Min, Hye-Jin\|Kim, Su Jin\|Lee, Yangsoon\|Park, Eun-Hee\|Ratakorn, Srisuttee\|Jhun, Byung Hak\|Oh, Sangtaek\|Johnston, Randal N\|Chung, Young-Hwa
PMID:	21196815

113.
Journal:	Biochem Biophys Res Commun. 2011 Feb 18;405(3):377-81.
Title:	Anti-MUC1 antibody inhibits EGF receptor signaling in cancer cells.
Author:	Hisatsune, Akinori\|Nakayama, Hideki\|Kawasaki, Mitsuru\|Horie, Ichiro\|Miyata, Takeshi\|Isohama, Yoichiro\|Kim, Kwang Chul\|Katsuki, Hiroshi
PMID:	21219855

114.
Journal:	Clin Cancer Res. 2011 Feb 1;17(3):483-93.
Title:	Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth.
Author:	Nagaraj, Nagathihalli S\|Washington, M Kay\|Merchant, Nipun B
PMID:	21266529

115.
Journal:	J Biol Chem. 2011 Mar 25;286(12):10495-504.
Title:	Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion.
Author:	Shields, Mario A\|Dangi-Garimella, Surabhi\|Krantz, Seth B\|Bentrem, David J\|Munshi, Hidayatullah G
PMID:	21288898

116.
Journal:	Biomed Pharmacother. 2011 Mar;65(2):123-31.
Title:	Promoted cancer growth by stimulating cell proliferation and decreasing apoptosis using a lentivirus-based EphB2 RNAi in pancreatic carcinoma CFPAC-1 cells.
Author:	Hua, Yong-qiang\|Ouyang, Hua-qiang\|Chen, Zhen\|Meng, Zhi-qiang\|Luo, Jian-min\|Lin, Jun-hua\|Zhou, Zhen-hua\|Chen, Hao\|Wang, Kun\|Liu, Lu-ming
PMID:	21292437

117.
Journal:	J Mol Med (Berl). 2011 Sep;89(9):877-89.
Title:	Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K-mTOR pathway in pancreatic adenocarcinoma.
Author:	Mirzoeva, Olga K\|Hann, Byron\|Hom, Yun K\|Debnath, Jayanta\|Aftab, Dana\|Shokat, Kevan\|Korn, W Michael
PMID:	21678117

118.
Journal:	Free Radic Biol Med. 2011 Sep 15;51(6):1164-74.
Title:	Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway.
Author:	Shin-Kang, Sonyo\|Ramsauer, Victoria P\|Lightner, Janet\|Chakraborty, Kanishka\|Stone, William\|Campbell, Sharon\|Reddy, Shrikanth A G\|Krishnan, Koyamangalath
PMID:	21723941

119.
Journal:	Cancer Biol Ther. 2011 Oct 1;12(7):574-85. Epub 2011 Oct 1.
Title:	Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Author:	Jiang, Yixing\|DiVittore, Nicole A\|Kaiser, James M\|Shanmugavelandy, Sriram S\|Fritz, Jennifer L\|Heakal, Yasser\|Tagaram, Hephzibah Rani S\|Cheng, Hua\|Cabot, Myles C\|Staveley-O'Carroll, Kevin F\|Tran, Melissa A\|Fox, Todd E\|Barth, Brian M\|Kester, Mark
PMID:	21795855

120.
Journal:	PLoS One. 2011;6(9):e25166.
Title:	Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.
Author:	Roy, Sanjit K\|Chen, Qinghe\|Fu, Junsheng\|Shankar, Sharmila\|Srivastava, Rakesh K
PMID:	21980390

121.
Journal:	World J Gastroenterol. 2011 Sep 7;17(33):3810-7.
Title:	Dickkopf3 overexpression inhibits pancreatic cancer cell growth in vitro.
Author:	Gu, Yu-Mei\|Ma, Yi-Hui\|Zhao, Wu-Gan\|Chen, Jie
PMID:	21987623

122.
Journal:	PLoS One. 2011;6(10):e26815.
Title:	DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance.
Author:	Danilov, Alexey V\|Neupane, Divas\|Nagaraja, Archana Sidalaghatta\|Feofanova, Elena V\|Humphries, Leigh Ann\|DiRenzo, James\|Korc, Murray
PMID:	22053213

123.
Journal:	Anticancer Res. 2011 Nov;31(11):3747-56.
Title:	Mechanisms underlying gemcitabine resistance in pancreatic cancer and sensitisation by the iMiD lenalidomide.
Author:	Fryer, Rosemary A\|Barlett, Blake\|Galustian, Christine\|Dalgleish, Angus G
PMID:	22110196

124.
Journal:	Cancer Epidemiol. 2012 Apr;36(2):206-11.
Title:	Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.
Author:	Dong, Xiaoqun\|Li, Yanan\|Tang, Hongwei\|Chang, Ping\|Hess, Kenneth R\|Abbruzzese, James L\|Li, Donghui
PMID:	21852217

125.
Journal:	J Gastroenterol. 2012 Feb;47(2):203-13.
Title:	Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression.
Author:	Mohri, Dai\|Asaoka, Yoshinari\|Ijichi, Hideaki\|Miyabayashi, Koji\|Kudo, Yotaro\|Seto, Motoko\|Ohta, Miki\|Tada, Motohisa\|Tanaka, Yasuo\|Ikenoue, Tsuneo\|Tateishi, Keisuke\|Isayama, Hiroyuki\|Kanai, Fumihiko\|Fukushima, Noriyoshi\|Tada, Minoru\|Kawabe, Takao\|Omata, Mas
PMID:	22041919

126.
Journal:	Carcinogenesis. 2012 Jan;33(1):191-6.
Title:	Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention.
Author:	Schuller, Hildegard M\|Al-Wadei, Hussein A N\|Ullah, Mohammad F\|Plummer, Howard K 3rd
PMID:	22072614

127.
Journal:	Mol Cancer Res. 2012 Feb;10(2):239-49.
Title:	Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3, alpha5, and alpha7.
Author:	Al-Wadei, Mohammed H\|Al-Wadei, Hussein A N\|Schuller, Hildegard M
PMID:	22188668

128.
Journal:	Ann Surg Oncol. 2012 Aug;19(8):2733-43.
Title:	VEGF-A/VEGFR-2 signaling plays an important role for the motility of pancreas cancer cells.
Author:	Doi, Yosuke\|Yashiro, Masakazu\|Yamada, Nobuya\|Amano, Ryosuke\|Noda, Satoru\|Hirakawa, Kosei
PMID:	22207048

129.
Journal:	Biochem Biophys Res Commun. 2012 Jan 20;417(3):1074-9.
Title:	RAS oncogenic signal upregulates EZH2 in pancreatic cancer.
Author:	Fujii, Satoshi\|Fukamachi, Katsumi\|Tsuda, Hiroyuki\|Ito, Kosei\|Ito, Yoshiaki\|Ochiai, Atsushi
PMID:	22222375

130.
Journal:	Mod Pathol. 2012 May;25(5):758-66.
Title:	Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma.
Author:	Chung, Yeon Tae\|Matkowskyj, Kristina A\|Li, Haonan\|Bai, Han\|Zhang, Wanying\|Tsao, Ming-Sound\|Liao, Jie\|Yang, Guang-Yu
PMID:	22222635

131.
Journal:	Int J Cancer. 2012 Oct 15;131(8):1951-62.
Title:	Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
Author:	Mohammed, Altaf\|Qian, Li\|Janakiram, Naveena B\|Lightfoot, Stan\|Steele, Vernon E\|Rao, Chinthalapally V
PMID:	22287227

132.
Journal:	Hepatogastroenterology. 2012 Mar-Apr;59(114):584-8.
Title:	Beta-adrenoceptor action on pancreatic cancer cell proliferation and tumor growth in mice.
Author:	Lin, Xueping\|Luo, Kai\|Lv, Zhongwei\|Huang, Jian
PMID:	22353526

133.
Journal:	Bioorg Med Chem. 2012 Apr 15;20(8):2520-6.
Title:	Growth inhibition and mechanism of action of p-dodecylaminophenol against refractory human pancreatic cancer and cholangiocarcinoma.
Author:	Imai, Masahiko\|Takahashi, Noriko
PMID:	22440084

134.
Journal:	Mol Cancer. 2012 Apr 26;11:24.
Title:	Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades.
Author:	Kunigal, Sateesh\|Ponnusamy, Moorthy P\|Momi, Navneet\|Batra, Surinder K\|Chellappan, Srikumar P
PMID:	22537161

135.
Journal:	Oncol Rep. 2012 Aug;28(2):519-26.
Title:	Combined effects of EGFR and Hedgehog signaling pathway inhibition on the proliferation and apoptosis of pancreatic cancer cells.
Author:	Qin, Chang-Fu\|Hao, Kun\|Tian, Xiao-Dong\|Xie, Xue-Hai\|Yang, Yin-Mo
PMID:	22581058

136.
Journal:	Front Biosci (Landmark Ed). 2012 Jun 1;17:2541-9.
Title:	BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Author:	Liu, Jun\|Ben, Qi-Wen\|Yao, Wei-Yan\|Zhang, Jian-Jun\|Chen, Da-Fan\|He, Xiang-Yi\|Li, Lei\|Yuan, Yao-Zong
PMID:	22652796

137.
Journal:	PLoS One. 2012;7(6):e39684.
Title:	Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer.
Author:	Deharvengt, Sophie\|Marmarelis, Melina\|Korc, Murray
PMID:	22761868

138.
Journal:	Br J Cancer. 2012 Jul 24;107(3):501-7.
Title:	Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation.
Author:	Sadanandam, A\|Sidhu, S S\|Wullschleger, S\|Singh, S\|Varney, M L\|Yang, C-S\|Ashour, A E\|Batra, S K\|Singh, R K
PMID:	22782341

139.
Journal:	Oncol Lett. 2012 Jun;3(6):1207-1212.
Title:	Overexpression of the B-type Eph and ephrin genes correlates with progression and pain in human pancreatic cancer.
Author:	Lu, Zhenhui\|Zhang, Yong\|Li, Zhaoyu\|Yu, Songning\|Zhao, Guozhong\|Li, Minghao\|Wang, Zuozhen\|Wang, Qi\|Yang, Yinxue
PMID:	22783419

140.
Journal:	Carcinogenesis. 2012 Sep;33(9):1745-53.
Title:	Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters.
Author:	Al-Wadei, Mohammed H\|Al-Wadei, Hussein A N\|Schuller, Hildegard M
PMID:	22791813

141.
Journal:	JOP. 2012 Jul 10;13(4):345-8.
Title:	Novel agents and new combination treatments on phase I studies on solid tumors and pancreatic cancer.
Author:	Strimpakos, Alexios S\|Syrigos, Kostas N\|Saif, Muhammad W
PMID:	22797386

142.
Journal:	Mol Cancer Res. 2012 Dec;10(12):1607-19.
Title:	Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
Author:	Gysin, Stephan\|Paquette, Jesse\|McMahon, Martin
PMID:	22833572

143.
Journal:	PLoS One. 2012;7(8):e42699.
Title:	Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling.
Author:	Song, Shumei\|Ji, Baoan\|Ramachandran, Vijaya\|Wang, Huamin\|Hafley, Margarete\|Logsdon, Craig\|Bresalier, Robert S
PMID:	22900040

144.
Journal:	Anat Rec (Hoboken). 2012 Dec;295(12):2122-8.
Title:	Reversal of multidrug resistance by gefitinib via RAF1/ERK pathway in pancreatic cancer cell line.
Author:	Xiao, Zhi\|Ding, Nianhua\|Xiao, Guiqing\|Wang, Shouman\|Wu, Yuhui\|Tang, Lili
PMID:	22907845

145.
Journal:	PLoS One. 2012;7(8):e43376.
Title:	Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice.
Author:	Al-Wadei, Hussein A N\|Al-Wadei, Mohammed H\|Ullah, Mohammad F\|Schuller, Hildegard M
PMID:	22916251

146.
Journal:	Zhonghua Yi Xue Za Zhi. 2012 Jul 10;92(26):1849-53.
Title:	[Effects and mechanisms of combined suppression of epidermal growth factor receptor and hedgehog signaling on proliferation in pancreatic cancer cells].
Author:	Qin, Chang-fu\|Tian, Xiao-dong\|Hao, Kun\|Yang, Yin-mo
PMID:	22944238

147.
Journal:	J Biol Chem. 2012 Nov 9;287(46):39115-24.
Title:	CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor kappaB: implications for bidirectional tumor-stromal interactions.
Author:	Singh, Ajay P\|Arora, Sumit\|Bhardwaj, Arun\|Srivastava, Sanjeev K\|Kadakia, Madhavi P\|Wang, Bin\|Grizzle, William E\|Owen, Laurie B\|Singh, Seema
PMID:	22995914

148.
Journal:	Biochim Biophys Acta. 2012 Dec;1823(12):2120-9.
Title:	Novel involvement of leukotriene B(4) receptor 2 through ERK activation by PP2A down-regulation in leukotriene B(4)-induced keratin phosphorylation and reorganization of pancreatic cancer cells.
Author:	Park, Mi Kyung\|Park, Youngran\|Shim, Jaegal\|Lee, Hye Ja\|Kim, Sanghee\|Lee, Chang Hoon
PMID:	23017243

149.
Journal:	Oncol Lett. 2012 Oct;4(4):783-791.
Title:	MACC1: A potential molecule associated with pancreatic cancer metastasis and chemoresistance.
Author:	Wang, Gang\|Kang, Mu-Xing\|Lu, Wen-Jie\|Chen, Ying\|Zhang, Bo\|Wu, Yu-Lian
PMID:	23205101

150.
Journal:	Mol Cell Biochem. 2013 Jan;372(1-2):83-94.
Title:	EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.
Author:	Shankar, Sharmila\|Marsh, Luke\|Srivastava, Rakesh K
PMID:	22971992

151.
Journal:	Cancer Lett. 2013 May 1;331(2):250-61.
Title:	Synergistic anticancer activity of HS-173, a novel PI3K inhibitor in combination with Sorafenib against pancreatic cancer cells.
Author:	Yun, Sun-Mi\|Jung, Kyung Hee\|Lee, Hyunseung\|Son, Mi Kwon\|Seo, Ju-Hyeon\|Yan, Hong Hua\|Park, Byung Hee\|Hong, Sungwoo\|Hong, Soon-Sun
PMID:	23340175

152.
Journal:	PLoS One. 2013;8(2):e52526.
Title:	Vitamin E delta-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism.
Author:	Hodul, Pamela J\|Dong, Yanbin\|Husain, Kazim\|Pimiento, Jose M\|Chen, Jiandong\|Zhang, Anying\|Francois, Rony\|Pledger, Warren J\|Coppola, Domenico\|Sebti, Said M\|Chen, Dung-Tsa\|Malafa, Mokenge P
PMID:	23393547

153.
Journal:	PLoS One. 2013;8(2):e57289.
Title:	Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.
Author:	Soares, Heloisa P\|Ni, Yang\|Kisfalvi, Krisztina\|Sinnett-Smith, James\|Rozengurt, Enrique
PMID:	23437362

154.
Journal:	Pancreas. 2013 Jul;42(5):781-5.
Title:	Metformin inhibits the growth of human pancreatic cancer xenografts.
Author:	Kisfalvi, Krisztina\|Moro, Aune\|Sinnett-Smith, James\|Eibl, Guido\|Rozengurt, Enrique
PMID:	23462329

155.
Journal:	J Exp Clin Cancer Res. 2013 Mar 6;32:12.
Title:	Enhancing sorafenib-mediated sensitization to gemcitabine in experimental pancreatic cancer through EMAP II.
Author:	Awasthi, Niranjan\|Zhang, Changhua\|Hinz, Stefan\|Schwarz, Margaret A\|Schwarz, Roderich E
PMID:	23497499

156.
Journal:	Int J Med Sci. 2013;10(5):634-40.
Title:	Proliferation enhanced by NGF-NTRK1 signaling makes pancreatic cancer cells more sensitive to 2DG-induced apoptosis.
Author:	Cheng, Yao\|Diao, Dong-mei\|Zhang, Hao\|Song, Yong-Chun\|Dang, Cheng-Xue
PMID:	23569426

157.
Journal:	Cell Biol Int. 2013 May;37(5):478-84.
Title:	Direct TGF-beta1 signaling between activated platelets and pancreatic cancer cells primes cisplatin insensitivity.
Author:	Chen, Hongxu\|Lan, Xiang\|Liu, Menggang\|Zhou, Bo\|Wang, Baoling\|Chen, Ping
PMID:	23584798

158.
Journal:	Lab Invest. 2013 Jun;93(6):720-32.
Title:	Transforming growth factor-alpha activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation.
Author:	Tahara, Hiroki\|Sato, Ken\|Yamazaki, Yuichi\|Ohyama, Tatsuya\|Horiguchi, Norio\|Hashizume, Hiroaki\|Kakizaki, Satoru\|Takagi, Hitoshi\|Ozaki, Iwata\|Arai, Hideo\|Hirato, Junko\|Jesenofsky, Ralf\|Masamune, Atsushi\|Mori, Masatomo
PMID:	23608755

159.
Journal:	PLoS One. 2013 May 8;8(5):e63969.
Title:	Low concentrations of metformin selectively inhibit CD133(+) cell proliferation in pancreatic cancer and have anticancer action.
Author:	Gou, Shanmiao\|Cui, Pengfei\|Li, Xiangsheng\|Shi, Pengfei\|Liu, Tao\|Wang, Chunyou
PMID:	23667692

160.
Journal:	PLoS One. 2013 Jun 10;8(6):e65403.
Title:	Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
Author:	Gotschel, Frank\|Berg, Daniela\|Gruber, Wolfgang\|Bender, Christian\|Eberl, Markus\|Friedel, Myriam\|Sonntag, Johanna\|Rungeler, Elena\|Hache, Hendrik\|Wierling, Christoph\|Nietfeld, Wilfried\|Lehrach, Hans\|Frischauf, Annemarie\|Schwartz-Albiez, Reinhard\|Aberger, Fri
PMID:	23762360

161.
Journal:	Biochem Biophys Res Commun. 2013 Aug 2;437(3):433-9.
Title:	miR-210 regulates the interaction between pancreatic cancer cells and stellate cells.
Author:	Takikawa, Tetsuya\|Masamune, Atsushi\|Hamada, Shin\|Nakano, Eriko\|Yoshida, Naoki\|Shimosegawa, Tooru
PMID:	23831622

162.
Journal:	Oncol Lett. 2013 Jun;5(6):1958-1964.
Title:	alpha-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells.
Author:	Yuan, Jiangtao\|Wu, Yaolu\|Lu, Guifang
PMID:	23833675

163.
Journal:	PLoS One. 2013 Jul 29;8(7):e69992.
Title:	Ron knockdown and Ron monoclonal antibody IMC-RON8 sensitize pancreatic cancer to histone deacetylase inhibitors (HDACi).
Author:	Zou, Yi\|Howell, Gillian M\|Humphrey, Lisa E\|Wang, Jing\|Brattain, Michael G
PMID:	23922886

164.
Journal:	Mol Cancer. 2013 Sep 11;12(1):104.
Title:	Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer.
Author:	Venkatasubbarao, Kolaparthi\|Peterson, Lindsay\|Zhao, Shujie\|Hill, Ping\|Cao, Lin\|Zhou, Qing\|Nawrocki, Steffan T\|Freeman, James W
PMID:	24025152

165.
Journal:	Bioorg Med Chem. 2013 Nov 1;21(21):6414-26.
Title:	Quinazolino linked 4beta-amidopodophyllotoxin conjugates regulate angiogenic pathway and control breast cancer cell proliferation.
Author:	Kamal, Ahmed\|Tamboli, Jaki R\|Ramaiah, M Janaki\|Adil, S F\|Pushpavalli, S N C V L\|Ganesh, Raksha\|Sarma, Pranjal\|Bhadra, Utpal\|Pal-Bhadra, Manika
PMID:	24055291

166.
Journal:	Cancer Res. 2013 Oct 15;73(20):6359-74.
Title:	Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Author:	Zhang, Yaqing\|Yan, Wei\|Collins, Meredith A\|Bednar, Filip\|Rakshit, Sabita\|Zetter, Bruce R\|Stanger, Ben Z\|Chung, Ivy\|Rhim, Andrew D\|di Magliano, Marina Pasca
PMID:	24097820

167.
Journal:	J Transl Med. 2013 Dec 14;11:311.
Title:	Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC).
Author:	Karamitopoulou, Eva\|Zlobec, Inti\|Gloor, Beat\|Kondi-Pafiti, Agathi\|Lugli, Alessandro\|Perren, Aurel
PMID:	24330423

168.
Journal:	PLoS One. 2013 Dec 31;8(12):e85502.
Title:	The MEK/ERK pathway promotes NOTCH signalling in pancreatic cancer cells.
Author:	Tremblay, Isabelle\|Pare, Emanuel\|Arsenault, Dominique\|Douziech, Melanie\|Boucher, Marie-Josee
PMID:	24392017

169.
Journal:	Mol Carcinog. 2014 Oct;53(10):787-92.
Title:	Up-regulated cten by FGF2 contributes to FGF2-mediated cell migration.
Author:	Hung, Shih-Ya\|Shih, Yi-Ping\|Chen, Michelle\|Lo, Su Hao
PMID:	23625726

170.
Journal:	Oncogene. 2014 Sep 18;33(38):4664-74.
Title:	microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-beta actions.
Author:	Ouyang, H\|Gore, J\|Deitz, S\|Korc, M
PMID:	24096486

171.
Journal:	Phytomedicine. 2014 Mar 15;21(4):491-6.
Title:	Novel synthetic oleanane triterpenoid AMR-MeOAc inhibits K-Ras through ERK, Akt and survivin in pancreatic cancer cells.
Author:	Rabi, Thangaiyan\|Venkatanarashiman, Mathuram
PMID:	24215674

172.
Journal:	J Cell Physiol. 2014 Jul;229(7):887-97.
Title:	Overexpression of calreticulin contributes to the development and progression of pancreatic cancer.
Author:	Sheng, Weiwei\|Chen, Chuanping\|Dong, Ming\|Zhou, Jianping\|Liu, Qingfeng\|Dong, Qi\|Li, Feng
PMID:	24264800

173.
Journal:	Oncol Rep. 2014 Feb;31(2):975-82.
Title:	Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK.
Author:	Bu, He-Qi\|Liu, Dian-Lei\|Wei, Wei-Tian\|Chen, Liang\|Huang, Hai\|Li, Ye\|Cui, Jun-Hui
PMID:	24297112

174.
Journal:	Cancer Res. 2014 Feb 15;74(4):1190-9.
Title:	Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.
Author:	Barcelo, Carles\|Paco, Noelia\|Morell, Mireia\|Alvarez-Moya, Blanca\|Bota-Rabassedas, Neus\|Jaumot, Montserrat\|Vilardell, Felip\|Capella, Gabriel\|Agell, Neus
PMID:	24371225

175.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Jan;30(1):23-7.
Title:	[Mechanism underlying pancreatic cancer cell resistance to mTOR inhibitor RAD001 via c-Raf/ERK1/2 activation].
Author:	Wei, Feng\|Zhang, Ping\|Qi, Jun\|Wang, Meng\|Wang, Guangyi
PMID:	24405594

176.
Journal:	Cancer Chemother Pharmacol. 2014 Apr;73(4):711-9.
Title:	Perifosine inhibits S6K1-Gli1 signaling and enhances gemcitabine-induced anti-pancreatic cancer efficiency.
Author:	Xin, Ying\|Shen, Xiang-di\|Cheng, Long\|Hong, De-fei\|Chen, Bin
PMID:	24519751

177.
Journal:	Mol Cancer. 2014 Feb 25;13:38.
Title:	Targeting the prohibitin scaffold-CRAF kinase interaction in RAS-ERK-driven pancreatic ductal adenocarcinoma.
Author:	Luan, Zhou\|He, Ying\|Alattar, Mohamed\|Chen, Zhishui\|He, Fan
PMID:	24568222

178.
Journal:	Clin Cancer Res. 2014 May 15;20(10):2793-804.
Title:	A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.
Author:	Tabernero, Josep\|Elez, Maria Elena\|Herranz, Maria\|Rico, Isabel\|Prudkin, Ludmila\|Andreu, Jordi\|Mateos, Jose\|Carreras, Maria Josep\|Han, May\|Gifford, James\|Credi, Marc\|Yin, Wei\|Agarwal, Shefali\|Komarnitsky, Philip\|Baselga, Jose
PMID:	24634378

179.
Journal:	Curr Cancer Drug Targets. 2014;14(4):348-56.
Title:	Hyperglycemia regulates TXNIP/TRX/ROS axis via p38 MAPK and ERK pathways in pancreatic cancer.
Author:	Li, Wei\|Wu, Zheng\|Ma, Qingyong\|Liu, Jiangbo\|Xu, Qinhong\|Han, Liang\|Duan, Wanxing\|Lv, Yunfu\|Wang, Fengfei\|Reindl, Katie M\|Wu, Erxi
PMID:	24720336

180.
Journal:	Curr Cancer Drug Targets. 2014;14(5):446-57.
Title:	The Activation of beta1-integrin by Type I Collagen Coupling with the Hedgehog Pathway Promotes the Epithelial-Mesenchymal Transition in Pancreatic Cancer.
Author:	Duan, Wanxing\|Ma, Jiguang\|Ma, Qingyong\|Xu, Qinhong\|Lei, Jianjun\|Han, Liang\|Li, Xuqi\|Wang, Zheng\|Wu, Zheng\|Lv, Shifang\|Ma, Zhenhua\|Liu, Mouzhu\|Wang, Fengfei\|Wu, Erxi
PMID:	24720337

181.
Journal:	Oncol Rep. 2014 Jun;31(6):2792-6.
Title:	Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.
Author:	Fontanil, Tania\|Mohamedi, Yamina\|Esteban, Manuel M\|Obaya, Alvaro J\|Cal, Santiago
PMID:	24756697

182.
Journal:	Mol Cancer Ther. 2014 Jul;13(7):1758-71.
Title:	Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.
Author:	Balic, Anamaria\|Sorensen, Morten Draeby\|Trabulo, Sara Maria\|Sainz, Bruno Jr\|Cioffi, Michele\|Vieira, Catarina R\|Miranda-Lorenzo, Irene\|Hidalgo, Manuel\|Kleeff, Joerg\|Erkan, Mert\|Heeschen, Christopher
PMID:	24785258

183.
Journal:	PLoS One. 2014 May 1;9(5):e96060.
Title:	PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling.
Author:	Ono, Hiroaki\|Basson, Marc D\|Ito, Hiromichi
PMID:	24788754

184.
Journal:	Int J Oncol. 2014 Jul;45(1):311-21.
Title:	HS-104, a PI3K inhibitor, enhances the anticancer efficacy of gemcitabine in pancreatic cancer.
Author:	Jung, Kyung Hee\|Yan, Hong Hua\|Fang, Zhenghuan\|Son, Mi Kwon\|Lee, Hyunseung\|Hong, Sungwoo\|Hong, Soon-Sun
PMID:	24819705

185.
Journal:	Cell Death Dis. 2014 May 22;5:e1241.
Title:	Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice.
Author:	Xiao, Z\|Li, L\|Li, Y\|Zhou, W\|Cheng, J\|Liu, F\|Zheng, P\|Zhang, Y\|Che, Y
PMID:	24853419

186.
Journal:	Oncol Lett. 2014 Jul;8(1):17-24.
Title:	High expression of erythropoietin-producing hepatoma cell line-B2 (EphB2) predicts the efficiency of the Qingyihuaji formula treatment in pancreatic cancer CFPAC-1 cells through the EphrinB1-EphB2 pathway.
Author:	Hua, Yong-Qiang\|Chen, Zhen\|Meng, Zhi-Qiang\|Chen, Hao\|Shen, Jian-Gang\|Wang, Kun\|Peng, Wang\|Shen, Ye-Hua\|Liu, Lu-Ming
PMID:	24959213

187.
Journal:	Cancer Sci. 2014 Sep;105(9):1212-9.
Title:	Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer.
Author:	Matsuda, Yoko\|Yoshimura, Hisashi\|Suzuki, Taeko\|Uchida, Eiji\|Naito, Zenya\|Ishiwata, Toshiyuki
PMID:	24975163

188.
Journal:	Neoplasia. 2014 Jul;16(7):562-71.
Title:	Co-treatment with panitumumab and trastuzumab augments response to the MEK inhibitor trametinib in a patient-derived xenograft model of pancreatic cancer.
Author:	Lindberg, James M\|Newhook, Timothy E\|Adair, Sara J\|Walters, Dustin M\|Kim, Alison J\|Stelow, Edward B\|Parsons, J Thomas\|Bauer, Todd W
PMID:	25117978

189.
Journal:	Gastroenterology. 2014 Nov;147(5):1119-33.e4.
Title:	Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Author:	Hermann, Patrick C\|Sancho, Patricia\|Canamero, Marta\|Martinelli, Paola\|Madriles, Francesc\|Michl, Patrick\|Gress, Thomas\|de Pascual, Ricardo\|Gandia, Luis\|Guerra, Carmen\|Barbacid, Mariano\|Wagner, Martin\|Vieira, Catarina R\|Aicher, Alexandra\|Real, Francisco X\|S
PMID:	25127677

190.
Journal:	Oncotarget. 2014 Oct 15;5(19):9150-68.
Title:	Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer.
Author:	Yan, Hong Hua\|Jung, Kyung Hee\|Son, Mi Kwon\|Fang, Zhenghuan\|Kim, Soo Jung\|Ryu, Ye-Lim\|Kim, Juyoung\|Kim, Mi-Hyun\|Hong, Soon-Sun
PMID:	25193856

191.
Journal:	Sci China Life Sci. 2014 Oct;57(10):1011-7.
Title:	Recombinant expression of different mutant K-ras gene in pancreatic cancer Bxpc-3 cells and its effects on chemotherapy sensitivity.
Author:	Shao, TengFei\|Zheng, YuanTing\|Zhao, Bei\|Li, Tao\|Cheng, KeGuang\|Cai, WeiMin
PMID:	25216706

192.
Journal:	Oncotarget. 2014 Sep 30;5(18):8778-89.
Title:	p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-kappaB pathway.
Author:	Tyagi, Nikhil\|Bhardwaj, Arun\|Singh, Ajay P\|McClellan, Steven\|Carter, James E\|Singh, Seema
PMID:	25238288

193.
Journal:	BMC Cancer. 2014 Sep 27;14:725.
Title:	Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro.
Author:	Banerjee, Jheelam\|Al-Wadei, Hussein An\|Al-Wadei, Mohammed H\|Dagnon, Koami\|Schuller, Hildegard M
PMID:	25260978

194.
Journal:	Cancer Lett. 2014 Dec 28;355(2):273-80.
Title:	Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway.
Author:	Zhang, Wanying\|Li, Haonan\|Yang, Yihe\|Liao, Jie\|Yang, Guang-Yu
PMID:	25304374

195.
Journal:	Curr Mol Med. 2014;14(9):1126-38.
Title:	Cholinergic receptors as target for cancer therapy in a systems medicine perspective.
Author:	Russo, P\|Del Bufalo, A\|Milic, M\|Salinaro, G\|Fini, M\|Cesario, A
PMID:	25324001

196.
Journal:	Cell Death Dis. 2014 Oct 23;5:e1480.
Title:	RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
Author:	Kang, R\|Hou, W\|Zhang, Q\|Chen, R\|Lee, Y J\|Bartlett, D L\|Lotze, M T\|Tang, D\|Zeh, H J
PMID:	25341034

197.
Journal:	BMC Cancer. 2014 Nov 6;14:814.
Title:	Effects of insulin on human pancreatic cancer progression modeled in vitro.
Author:	Chan, Michelle T\|Lim, Gareth E\|Skovso, Sos\|Yang, Yu Hsuan Carol\|Albrecht, Tobias\|Alejandro, Emilyn U\|Hoesli, Corinne A\|Piret, James M\|Warnock, Garth L\|Johnson, James D
PMID:	25373319

198.
Journal:	Hormones (Athens). 2014 Oct-Dec;13(4):498-508.
Title:	Anticancer effects of metformin on neuroendocrine tumor cells in vitro.
Author:	Vlotides, George\|Tanyeri, Ayse\|Spampatti, Matilde\|Zitzmann, Kathrin\|Chourdakis, Michael\|Spttl, Chourdakis\|Maurer, Julian\|Nolting, Svenja\|Goke, Burkhard\|Auernhammer, Christoph J
PMID:	25402373

199.
Journal:	Acta Histochem. 2014 Oct;116(8):1434-42.
Title:	Dynamic distribution of ERK, p38 and JNK during the development of pancreatic ductal adenocarcinoma.
Author:	Amsterdam, Abraham\|Shpigner, Lotem\|Raanan, Calanit\|Schreiber, Letizia\|Melzer, Ehud\|Seger, Rony
PMID:	25440531

200.
Journal:	PLoS One. 2014 Dec 10;9(12):e114573.
Title:	Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells.
Author:	Ming, Ming\|Sinnett-Smith, James\|Wang, Jia\|Soares, Heloisa P\|Young, Steven H\|Eibl, Guido\|Rozengurt, Enrique
PMID:	25493642

201.
Journal:	Int J Clin Exp Pathol. 2014 Oct 15;7(11):7536-44. eCollection 2014.
Title:	Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.
Author:	Qin, Yong\|Ye, Guan-Xiong\|Wu, Cheng-Jun\|Wang, Shi\|Pan, De-Biao\|Jiang, Jin-Yan\|Fu, Jing\|Xu, Sheng-Qian
PMID:	25550789

202.
Journal:	Oncogene. 2015 May 21;34(21):2801-6.
Title:	Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey.
Author:	Park, J T\|Johnson, N\|Liu, S\|Levesque, M\|Wang, Y J\|Ho, H\|Huso, D\|Maitra, A\|Parsons, M J\|Prescott, J D\|Leach, S D
PMID:	25065594

203.
Journal:	Tumour Biol. 2015 Feb;36(2):1015-22.
Title:	CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer.
Author:	Fu, Lin\|Dong, Qianze\|Xie, Chengyao\|Wang, Yan\|Li, Qingchang
PMID:	25318601

204.
Journal:	Biochim Biophys Acta. 2015 Jan;1853(1):157-65.
Title:	Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1alpha and beta-catenin via a p-21 activated kinase 1-dependent pathway.
Author:	Huynh, Nhi\|Beutler, John A\|Shulkes, Arthur\|Baldwin, Graham S\|He, Hong
PMID:	25409929

205.
Journal:	Naunyn Schmiedebergs Arch Pharmacol. 2015 Mar;388(3):295-304.
Title:	Lupeol inhibits proliferation and induces apoptosis of human pancreatic cancer PCNA-1 cells through AKT/ERK pathways.
Author:	Liu, Yan\|Bi, Tingting\|Wang, Gang\|Dai, Wei\|Wu, Guoliang\|Qian, Liqiang\|Gao, Quangen\|Shen, Genhai
PMID:	25418891

206.
Journal:	Biochem Biophys Res Commun. 2015 Jan 16;456(3):821-6.
Title:	The glucosylceramide synthase inhibitor PDMP sensitizes pancreatic cancer cells to MEK/ERK inhibitor AZD-6244.
Author:	Wang, Ting\|Wei, Jue\|Wang, Na\|Ma, Jia-Li\|Hui, Ping-Ping
PMID:	25498501

207.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):407-18.
Title:	A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer.
Author:	Pan, Youli\|Zheng, Mingwu\|Zhong, Lei\|Yang, Jiao\|Zhou, Shu\|Qin, Ya\|Xiang, Rong\|Chen, Yuzong\|Yang, Sheng-Yong
PMID:	25519702

208.
Journal:	Acta Pharmacol Sin. 2015 Mar;36(3):291-7.
Title:	The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer.
Author:	Guin, Sunny\|Theodorescu, Dan
PMID:	25557115

209.
Journal:	Br J Cancer. 2015 Feb 3;112(3):514-22.
Title:	Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1alpha pathway to predict survival in resectable pancreatic cancer.
Author:	Qin, R\|Smyrk, T C\|Reed, N R\|Schmidt, R L\|Schnelldorfer, T\|Chari, S T\|Petersen, G M\|Tang, A H
PMID:	25584484

210.
Journal:	Oncotarget. 2015 Mar 10;6(7):4829-44.
Title:	Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: involvement of protein kinase C-theta activation.
Author:	Takahashi, Tetsuyuki\|Uehara, Hisanori\|Ogawa, Hirohisa\|Umemoto, Hitomi\|Bando, Yoshimi\|Izumi, Keisuke
PMID:	25638159

211.
Journal:	IUBMB Life. 2015 Jan;67(1):42-53.
Title:	MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer.
Author:	Guo, Rende\|Gu, Jianhua\|Zhang, Zhibin\|Wang, Yi\|Gu, Chuan
PMID:	25646808

212.
Journal:	Mol Cancer Ther. 2015 Apr;14(4):1014-23.
Title:	Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
Author:	Soares, Heloisa P\|Ming, Ming\|Mellon, Michelle\|Young, Steven H\|Han, Liang\|Sinnet-Smith, James\|Rozengurt, Enrique
PMID:	25673820

213.
Journal:	Apoptosis. 2015 Jun;20(6):843-57.
Title:	Tenascin-C induces resistance to apoptosis in pancreatic cancer cell through activation of ERK/NF-kappaB pathway.
Author:	Shi, Meiyan\|He, Xiaodan\|Wei, Wei\|Wang, Juan\|Zhang, Ti\|Shen, Xiaohong
PMID:	25690319

214.
Journal:	Mol Cancer Res. 2015 May;13(5):863-9.
Title:	Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method.
Author:	von Burstin, Johannes\|Diersch, Sandra\|Schneider, Gunter\|Reichert, Maximilian\|Rustgi, Anil K\|Schmid, Roland M
PMID:	25724428

215.
Journal:	Cell Res. 2015 May;25(5):561-73.
Title:	ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Author:	Ji, Shunrong\|Qin, Yi\|Shi, Si\|Liu, Xiangyuan\|Hu, Hongli\|Zhou, Hu\|Gao, Jing\|Zhang, Bo\|Xu, Wenyan\|Liu, Jiang\|Liang, Dingkong\|Liu, Liang\|Liu, Chen\|Long, Jiang\|Zhou, Haijun\|Chiao, Paul J\|Xu, Jin\|Ni, Quanxing\|Gao, Daming\|Yu, Xianjun
PMID:	25753158

216.
Journal:	Bioorg Med Chem. 2015 Apr 1;23(7):1386-94.
Title:	Dual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitor.
Author:	Van Dort, Marcian E\|Galban, Stefanie\|Wang, Hanxiao\|Sebolt-Leopold, Judith\|Whitehead, Christopher\|Hong, Hao\|Rehemtulla, Alnawaz\|Ross, Brian D
PMID:	25766633

217.
Journal:	Int J Oncol. 2015;46(6):2613-20.
Title:	Superoxide dismutase promotes the epithelial-mesenchymal transition of pancreatic cancer cells via activation of the H2O2/ERK/NF-kappaB axis.
Author:	Li, Wei\|Cao, Lei\|Han, Liang\|Xu, Qinhong\|Ma, Qingyong
PMID:	25825208

218.
Journal:	BMC Cancer. 2015 Apr 4;15:223.
Title:	Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors.
Author:	Urtasun, Nerea\|Vidal-Pla, Anna\|Perez-Torras, Sandra\|Mazo, Adela
PMID:	25886138

219.
Journal:	Oncotarget. 2015 Jun 20;6(17):15297-310.
Title:	A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion.
Author:	Butler, Amanda M\|Scotti Buzhardt, Michele L\|Erdogan, Eda\|Li, Shuhua\|Inman, Kristin S\|Fields, Alan P\|Murray, Nicole R
PMID:	25915428

220.
Journal:	Cancer Lett. 2015 Aug 1;364(1):17-24.
Title:	LIM-only protein FHL2 critically determines survival and radioresistance of pancreatic cancer cells.
Author:	Zienert, Elisa\|Eke, Iris\|Aust, Daniela\|Cordes, Nils
PMID:	25917075

221.
Journal:	Oncotarget. 2015 Aug 28;6(25):21085-99.
Title:	Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells.
Author:	Lakshmanan, Imayavaramban\|Seshacharyulu, Parthasarathy\|Haridas, Dhanya\|Rachagani, Satyanarayana\|Gupta, Suprit\|Joshi, Suhasini\|Guda, Chittibabu\|Yan, Ying\|Jain, Maneesh\|Ganti, Apar K\|Ponnusamy, Moorthy P\|Batra, Surinder K
PMID:	26035354

222.
Journal:	Biochem Biophys Res Commun. 2015 Aug 7;463(4):612-7.
Title:	Up-regulation of fatty acid synthase induced by EGFR/ERK activation promotes tumor growth in pancreatic cancer.
Author:	Bian, Yong\|Yu, Yun\|Wang, Shanshan\|Li, Lin
PMID:	26043686

223.
Journal:	Sci Rep. 2015 Jul 2;5:11836.
Title:	Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.
Author:	Shen, Meng\|Wu, Meng-Yao\|Chen, Long-Pei\|Zhi, Qiaoming\|Gong, Fei-Ran\|Chen, Kai\|Li, Dao-Ming\|Wu, Yadi\|Tao, Min\|Li, Wei
PMID:	26135631

224.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5563-77.
Title:	The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).
Author:	Vena, Francesca\|Li Causi, Eleonora\|Rodriguez-Justo, Manuel\|Goodstal, Samantha\|Hagemann, Thorsten\|Hartley, John A\|Hochhauser, Daniel
PMID:	26228206

225.
Journal:	Adv Biol Regul. 2015 Sep;59:65-81.
Title:	Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells.
Author:	Fitzgerald, Timothy L\|Lertpiriyapong, Kvin\|Cocco, Lucio\|Martelli, Alberto M\|Libra, Massimo\|Candido, Saverio\|Montalto, Giuseppe\|Cervello, Melchiorre\|Steelman, Linda\|Abrams, Stephen L\|McCubrey, James A
PMID:	26257206

226.
Journal:	BMC Cancer. 2015 Aug 11;15:581.
Title:	Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation.
Author:	Yadav, Vikas\|Varshney, Pallavi\|Sultana, Sarwat\|Yadav, Jyoti\|Saini, Neeru
PMID:	26260159

227.
Journal:	Int J Clin Exp Pathol. 2015 Jun 1;8(6):6724-31. eCollection 2015.
Title:	Expression of CD44 in pancreatic cancer and its significance.
Author:	Li, Xiao-Ping\|Zhang, Xiao-Wei\|Zheng, Lei-Zhen\|Guo, Wei-Jian
PMID:	26261555

228.
Journal:	DNA Cell Biol. 2015 Oct;34(10):610-7.
Title:	The Antipancreatic Cancer Activity of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2.
Author:	Chen, Bo\|Xu, Ming\|Zhang, Hui\|Xu, Ming-zheng\|Wang, Xu-jing\|Tang, Qing-he\|Tang, Jian-ying
PMID:	26284306

229.
Journal:	Oncotarget. 2015 Nov 24;6(37):39521-37.
Title:	Novel agents for advanced pancreatic cancer.
Author:	Akinleye, Akintunde\|Iragavarapu, Chaitanya\|Furqan, Muhammad\|Cang, Shundong\|Liu, Delong
PMID:	26369833

230.
Journal:	Sci Rep. 2015 Sep 22;5:14404.
Title:	Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling.
Author:	Chai, Xinqun\|Chu, Hongpeng\|Yang, Xuan\|Meng, Yuanpu\|Shi, Pengfei\|Gou, Shanmiao
PMID:	26391180

231.
Journal:	Oncol Rep. 2015 Dec;34(6):3304-10.
Title:	The flavonoid p-hydroxycinnamic acid exhibits anticancer effects in human pancreatic cancer MIA PaCa-2 cells in vitro: Comparison with gemcitabine.
Author:	Yamaguchi, Masayoshi\|Murata, Tomiyasu\|El-Rayes, Bassel F\|Shoji, Mamoru
PMID:	26397991

232.
Journal:	Oncotarget. 2015 Oct 13;6(31):31119-33.
Title:	Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer.
Author:	Li, Wei\|Ma, Zhenhua\|Ma, Jiguang\|Li, Xuqi\|Xu, Qinhong\|Duan, Wanxing\|Chen, Xin\|Lv, Yunfu\|Zhou, Shuang\|Wu, Erxi\|Ma, Qingyong\|Huo, Xiongwei
PMID:	26439801

233.
Journal:	Biochim Biophys Acta. 2015 Dec;1849(12):1375-84.
Title:	The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-kappaB and RalB signaling pathways.
Author:	Vasseur, Romain\|Skrypek, Nicolas\|Duchene, Belinda\|Renaud, Florence\|Martinez-Maqueda, Daniel\|Vincent, Audrey\|Porchet, Nicole\|Van Seuningen, Isabelle\|Jonckheere, Nicolas
PMID:	26477488

234.
Journal:	Hepatobiliary Pancreat Dis Int. 2015 Dec;14(6):642-50.
Title:	Trametinib and dactolisib but not regorafenib exert antiproliferative effects on rat pancreatic stellate cells.
Author:	Witteck, Laura\|Jaster, Robert
PMID:	26663013

235.
Journal:	Tumour Biol. 2016 Feb;37(2):2519-26.
Title:	Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.
Author:	Tveteraas, Ingun Heiene\|Aasrum, Monica\|Brusevold, Ingvild Johnsen\|Odegard, John\|Christoffersen, Thoralf\|Sandnes, Dagny
PMID:	26386720

236.
Journal:	Tumour Biol. 2016 Apr;37(4):5117-31.
Title:	Integrin beta6 acts as an unfavorable prognostic indicator and promotes cellular malignant behaviors via ERK-ETS1 pathway in pancreatic ductal adenocarcinoma (PDAC).
Author:	Li, Zequn\|Lin, Pengfei\|Gao, Chao\|Peng, Cheng\|Liu, Song\|Gao, Huijie\|Wang, Ben\|Wang, Jiayong\|Niu, Jun\|Niu, Weibo
PMID:	26547582

237.
Journal:	Cancer Res. 2016 Jan 15;76(2):418-28.
Title:	Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology.
Author:	Dutta, Samikshan\|Roy, Sohini\|Polavaram, Navatha S\|Stanton, Marissa J\|Zhang, Heyu\|Bhola, Tanvi\|Honscheid, Pia\|Donohue, Terrence M Jr\|Band, Hamid\|Batra, Surinder K\|Muders, Michael H\|Datta, Kaustubh
PMID:	26560516

238.
Journal:	Cancer Lett. 2016 Feb 28;371(2):187-93.
Title:	Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM.
Author:	Liao, Jie\|Hwang, Sung Hee\|Li, Haonan\|Yang, Yihe\|Yang, Jun\|Wecksler, Aaron T\|Liu, Jun-Yan\|Hammock, Bruce D\|Yang, Guang-Yu
PMID:	26683769

239.
Journal:	Cancer Cell. 2016 Jan 11;29(1):75-89.
Title:	Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.
Author:	Hayes, Tikvah K\|Neel, Nicole F\|Hu, Chaoxin\|Gautam, Prson\|Chenard, Melissa\|Long, Brian\|Aziz, Meraj\|Kassner, Michelle\|Bryant, Kirsten L\|Pierobon, Mariaelena\|Marayati, Raoud\|Kher, Swapnil\|George, Samuel D\|Xu, Mai\|Wang-Gillam, Andrea\|Samatar, Ahmed A\|Maitra,
PMID:	26725216

240.
Journal:	Cell Cycle. 2016;15(3):381-93.
Title:	Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-kappaB pathway dependent repression of PP2Ac.
Author:	Tao, Min\|Liu, Lu\|Shen, Meng\|Zhi, Qiaoming\|Gong, Fei-Ran\|Zhou, Binhua P\|Wu, Yadi\|Liu, Haiyan\|Chen, Kai\|Shen, Bairong\|Wu, Meng-Yao\|Shou, Liu-Mei\|Li, Wei
PMID:	26761431

241.
Journal:	Cancer Biol Ther. 2016;17(2):188-98.
Title:	Hypoxia regulates ABCG2 activity through the activivation of ERK1/2/HIF-1alpha and contributes to chemoresistance in pancreatic cancer cells.
Author:	He, Xiaodan\|Wang, Juan\|Wei, Wei\|Shi, Meiyan\|Xin, Beibei\|Zhang, Ti\|Shen, Xiaohong
PMID:	26785721

242.
Journal:	Sci Rep. 2016 Jan 25;6:19819.
Title:	Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition.
Author:	Subramani, Ramadevi\|Gonzalez, Elizabeth\|Arumugam, Arunkumar\|Nandy, Sushmita\|Gonzalez, Viviana\|Medel, Joshua\|Camacho, Fernando\|Ortega, Andrew\|Bonkoungou, Sandrine\|Narayan, Mahesh\|Dwivedi, Alok kumar\|Lakshmanaswamy, Rajkumar
PMID:	26804739

243.
Journal:	Ann Surg Oncol. 2016 Jun;23(6):1993-2000.
Title:	Adjuvant Trametinib Delays the Outgrowth of Occult Pancreatic Cancer in a Mouse Model of Patient-Derived Liver Metastasis.
Author:	Newhook, Timothy E\|Lindberg, James M\|Adair, Sara J\|Kim, Alison J\|Stelow, Edward B\|Rahma, Osama E\|Parsons, J Thomas\|Bauer, Todd W
PMID:	26847682

244.
Journal:	Cancer Res. 2016 Apr 15;76(8):2243-2253.
Title:	PR55alpha Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling.
Author:	Hein, Ashley L\|Seshacharyulu, Parthasarathy\|Rachagani, Satyanarayana\|Sheinin, Yuri M\|Ouellette, Michel M\|Ponnusamy, Moorthy P\|Mumby, Marc C\|Batra, Surinder K\|Yan, Ying
PMID:	26893480

245.
Journal:	Cancer Res. 2016 May 1;76(9):2612-25.
Title:	Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma.
Author:	Hijiya, Naoki\|Tsukamoto, Yoshiyuki\|Nakada, Chisato\|Tung Nguyen, Lam\|Kai, Tomoki\|Matsuura, Keiko\|Shibata, Kohei\|Inomata, Masafumi\|Uchida, Tomohisa\|Tokunaga, Akinori\|Amada, Kohei\|Shirao, Kuniaki\|Yamada, Yasunari\|Mori, Hiromu\|Takeuchi, Ichiro\|Seto, Masao\|Aok
PMID:	26941286

246.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G1124-37.
Title:	Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
Author:	Vorvis, Christina\|Hatziapostolou, Maria\|Mahurkar-Joshi, Swapna\|Koutsioumpa, Marina\|Williams, Jennifer\|Donahue, Timothy R\|Poultsides, George A\|Eibl, Guido\|Iliopoulos, Dimitrios
PMID:	27151939

247.
Journal:	Nat Genet. 2016 Jul;48(7):747-57.
Title:	Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Author:	Zheng, Jian\|Huang, Xudong\|Tan, Wen\|Yu, Dianke\|Du, Zhongli\|Chang, Jiang\|Wei, Lixuan\|Han, Yaling\|Wang, Chengfeng\|Che, Xu\|Zhou, Yifeng\|Miao, Xiaoping\|Jiang, Guoliang\|Yu, Xianjun\|Yang, Xianghong\|Cao, Guangwen\|Zuo, Chaohui\|Li, Zhaoshen\|Wang, Chunyou\|Cheung, Si
PMID:	27213290

248.
Journal:	Oncotarget. 2016 Jun 28;7(26):39996-40011.
Title:	Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis.
Author:	Hanson, Ryan L\|Brown, Roger B\|Steele, Maria M\|Grandgenett, Paul M\|Grunkemeyer, James A\|Hollingsworth, Michael A
PMID:	27220889

249.
Journal:	Oncotarget. 2016 Jun 28;7(26):40148-40159.
Title:	Periostin promotes tumor angiogenesis in pancreatic cancer via Erk/VEGF signaling.
Author:	Liu, Yang\|Li, Fan\|Gao, Feng\|Xing, Lingxi\|Qin, Peng\|Liang, Xingxin\|Zhang, Jiajie\|Qiao, Xiaohui\|Lin, Lizhou\|Zhao, Qian\|Du, Lianfang
PMID:	27223086

250.
Journal:	Biochem Biophys Res Commun. 2016 Aug 5;476(4):260-266.
Title:	The preclinical evaluation of TIC10/ONC201 as an anti-pancreatic cancer agent.
Author:	Zhang, Qiangbo\|Wang, Hong\|Ran, Lin\|Zhang, Zongli\|Jiang, Runde
PMID:	27233611

251.
Journal:	Int J Oncol. 2016 Aug;49(2):735-43.
Title:	Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Author:	Cao, Lei\|Chen, Xin\|Xiao, Xue\|Ma, Qingyong\|Li, Wei
PMID:	27278736

252.
Journal:	Toxicon. 2016 Sep 1;119:203-17.
Title:	Isolation, characterization and screening of the in vitro cytotoxic activity of a novel L-amino acid oxidase (LAAOcdt) from Crotalus durissus terrificus venom on human cancer cell lines.
Author:	Teixeira, Tuila Leveghim\|Oliveira Silva, Viviane Aline\|da Cunha, Daniel Batista\|Polettini, Flavia Lino\|Thomaz, Camila Daniele\|Pianca, Ariana Aparecida\|Zambom, Fabiana Leticia\|da Silva Leitao Mazzi, Denise Pimenta\|Reis, Rui Manuel\|Mazzi, Mauricio Ventura
PMID:	27317870

253.
Journal:	Cancer Lett. 2016 Sep 28;380(1):87-97.
Title:	Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis.
Author:	Lu, Yun-Xin\|Ju, Huai-Qiang\|Wang, Feng\|Chen, Le-Zong\|Wu, Qi-Nian\|Sheng, Hui\|Mo, Hai-Yu\|Pan, Zhi-Zhong\|Xie, Dan\|Kang, Tie-Bang\|Chen, Gong\|Yun, Jing-Ping\|Zeng, Zhao-Lei\|Xu, Rui-Hua
PMID:	27322737

254.
Journal:	Cancer Lett. 2016 Sep 28;380(1):98-105.
Title:	The hepatitis B virus X protein promotes pancreatic cancer through modulation of the PI3K/AKT signaling pathway.
Author:	Chen, Yiwen\|Bai, Xueli\|Zhang, Qi\|Wen, Liang\|Su, Wei\|Fu, Qihan\|Sun, Xu\|Lou, Yu\|Yang, Jiaqi\|Zhang, Jingying\|Chen, Qi\|Wang, Jianxin\|Liang, Tingbo
PMID:	27339327

255.
Journal:	Pharmacol Res. 2016 Sep;111:757-766.
Title:	Selective GPR55 antagonism reduces chemoresistance in cancer cells.
Author:	Singh, Nagendra S\|Bernier, Michel\|Wainer, Irving W
PMID:	27423937

256.
Journal:	Cell Biol Int. 2016 Oct;40(10):1050-61.
Title:	Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin.
Author:	Gamperl, Hans\|Plattfaut, Corinna\|Freund, Annika\|Quecke, Tabea\|Theophil, Friederike\|Gieseler, Frank
PMID:	27435911

257.
Journal:	Oncotarget. 2016 Sep 20;7(38):61469-61484.
Title:	Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.
Author:	Yamamoto, Keisuke\|Tateishi, Keisuke\|Kudo, Yotaro\|Hoshikawa, Mayumi\|Tanaka, Mariko\|Nakatsuka, Takuma\|Fujiwara, Hiroaki\|Miyabayashi, Koji\|Takahashi, Ryota\|Tanaka, Yasuo\|Ijichi, Hideaki\|Nakai, Yousuke\|Isayama, Hiroyuki\|Morishita, Yasuyuki\|Aoki, Taku\|Sakamoto
PMID:	27528027

258.
Journal:	Pharmacol Ther. 2016 Dec;168:29-42.
Title:	KRAS-related proteins in pancreatic cancer.
Author:	Mann, Karen M\|Ying, Haoqiang\|Juan, Joseph\|Jenkins, Nancy A\|Copeland, Neal G
PMID:	27595930

259.
Journal:	Sci Rep. 2016 Sep 9;6:32809.
Title:	Paeoniflorin Potentiates the Inhibitory Effects of Erlotinib in Pancreatic Cancer Cell Lines by Reducing ErbB3 Phosphorylation.
Author:	Hao, Jian\|Yang, Xue\|Ding, Xiu-Li\|Guo, Lei-Ming\|Zhu, Cui-Hong\|Ji, Wei\|Zhou, Tong\|Wu, Xiong-Zhi
PMID:	27609096

260.
Journal:	J Biol Inorg Chem. 2016 Dec;21(8):919-929.
Title:	Bis(acetylacetonato)-oxidovanadium(IV) and sodium metavanadate inhibit cell proliferation via ROS-induced sustained MAPK/ERK activation but with elevated AKT activity in human pancreatic cancer AsPC-1 cells.
Author:	Wu, Jing-Xuan\|Hong, Yi-Hua\|Yang, Xiao-Gai
PMID:	27614430

261.
Journal:	Oncotarget. 2016 Oct 18;7(42):68412-68433.
Title:	Dual oxidase 2 and pancreatic adenocarcinoma: IFN-gamma-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1alpha and VEGF-A.
Author:	Wu, Yongzhong\|Meitzler, Jennifer L\|Antony, Smitha\|Juhasz, Agnes\|Lu, Jiamo\|Jiang, Guojian\|Liu, Han\|Hollingshead, Melinda\|Haines, Diana C\|Butcher, Donna\|Panter, Michaela S\|Roy, Krishnendu\|Doroshow, James H
PMID:	27637085

262.
Journal:	Pancreatology. 2016 Nov - Dec;16(6):1005-1014.
Title:	Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer.
Author:	Xin, Beibei\|He, Xiaodan\|Wang, Juan\|Cai, Jun\|Wei, Wei\|Zhang, Ti\|Shen, Xiaohong
PMID:	27654574

263.
Journal:	Oncol Rep. 2016 Nov;36(5):2861-2867.
Title:	Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-kappaB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer.
Author:	Li, Weimin\|Wu, Jiansheng\|Li, Zhiyin\|Zhou, Zhibo\|Zheng, Chao\|Lin, Le\|Tan, Binbin\|Huang, Min\|Fan, Mengdi
PMID:	27666165

264.
Journal:	Exp Mol Med. 2016 Sep 30;48(9):e261.
Title:	CTHRC1 promotes angiogenesis by recruiting Tie2-expressing monocytes to pancreatic tumors.
Author:	Lee, Jaemin\|Song, Jinhoi\|Kwon, Eun-Soo\|Jo, Seongyea\|Kang, Min Kyung\|Kim, Yeon Jeong\|Hwang, Yeonsil\|Bae, Hosung\|Kang, Tae Heung\|Chang, Suhwan\|Cho, Hee Jun\|Kim, Song Cheol\|Kim, Seokho\|Koh, Sang Seok
PMID:	27686285

265.
Journal:	Oncol Rep. 2016 Dec;36(6):3413-3420.
Title:	c-Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma.
Author:	You, Lei\|Ren, Xiaoxia\|Du, Yongxing\|Zhao, Wenjing\|Cui, Ming\|Chen, Ge\|Zhao, Yupei
PMID:	27748943

266.
Journal:	Oncotarget. 2016 Nov 22;7(47):77916-77925.
Title:	Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling.
Author:	Cheng, Xi\|Wang, Bingrui\|Jin, Zhijian\|Ma, Ding\|Yang, Weiping\|Zhao, Ren\|Jing, Xiaoqian\|Shen, Baiyong\|Peng, Chenghong\|Qiu, Weihua
PMID:	27788491

267.
Journal:	Clin Cancer Res. 2017 Jan 15;23(2):489-502.
Title:	IL-21 Enhances Natural Killer Cell Response to Cetuximab-Coated Pancreatic Tumor Cells.
Author:	McMichael, Elizabeth L\|Jaime-Ramirez, Alena Cristina\|Guenterberg, Kristan D\|Luedke, Eric\|Atwal, Lakhvir S\|Campbell, Amanda R\|Hu, Zhiwei\|Tatum, Armika S\|Kondadasula, Sri Vidya\|Mo, Xiaokui\|Tridandapani, Susheela\|Bloomston, Mark\|Ellison, E Christopher\|Willia
PMID:	27435400

268.
Journal:	Semin Cancer Biol. 2017 Feb;42:70-80.
Title:	Smyd3-associated regulatory pathways in cancer.
Author:	Giakountis, Antonis\|Moulos, Panagiotis\|Sarris, Michalis E\|Hatzis, Pantelis\|Talianidis, Iannis
PMID:	27554136

269.
Journal:	Mol Carcinog. 2017 Apr;56(4):1344-1360.
Title:	Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells.
Author:	Quinn, Sierra N\|Graves, Sarai H\|Dains-McGahee, Clayton\|Friedman, Emilee M\|Hassan, Humma\|Witkowski, Piotr\|Sabbatini, Maria E
PMID:	27891679

270.
Journal:	Cancer Lett. 2017 Mar 1;388:303-311.
Title:	ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Author:	Liang, Chen\|Qin, Yi\|Zhang, Bo\|Ji, Shunrong\|Shi, Si\|Xu, Wenyan\|Liu, Jiang\|Xiang, Jinfeng\|Liang, Dingkong\|Hu, Qiangsheng\|Ni, Quanxing\|Yu, Xianjun\|Xu, Jin
PMID:	28025100

271.
Journal:	PLoS One. 2017 Jan 4;12(1):e0169335.
Title:	The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways.
Author:	Youns, Msmall a, Cyrillichmoud\|Abdel Halim Hegazy, Wael
PMID:	28052097

272.
Journal:	Cancer Cell Int. 2017 Jan 10;17:12.
Title:	HNRNPA2B1 regulates the epithelial-mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway.
Author:	Dai, Shengjie\|Zhang, Jie\|Huang, Shihao\|Lou, Bin\|Fang, Binbo\|Ye, Tingting\|Huang, Xince\|Chen, Bicheng\|Zhou, Mengtao
PMID:	28077929

273.
Journal:	Mol Cancer Res. 2017 Feb;15(2):201-212.
Title:	Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Author:	Liang, Chen\|Qin, Yi\|Zhang, Bo\|Ji, Shunrong\|Shi, Si\|Xu, Wenyan\|Liu, Jiang\|Xiang, Jinfeng\|Liang, Dingkong\|Hu, Qiangsheng\|Ni, Quanxing\|Xu, Jin\|Yu, Xianjun
PMID:	28108627

274.
Journal:	PLoS One. 2017 Jan 23;12(1):e0170390.
Title:	The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation.
Author:	Jahny, Elisabeth\|Yang, Hai\|Liu, Bin\|Jahnke, Beatrix\|Lademann, Franziska\|Knosel, Thomas\|Rummele, Petra\|Grutzmann, Robert\|Aust, Daniela E\|Pilarsky, Christian\|Denz, Axel
PMID:	28114355

275.
Journal:	Cancer Sci. 2017 May;108(5):1049-1057.
Title:	Novel small molecule inhibiting CDCP1-PKCdelta pathway reduces tumor metastasis and proliferation.
Author:	Nakashima, Katsuhiko\|Uekita, Takamasa\|Yano, Shigenobu\|Kikuchi, Jun-Ichi\|Nakanishi, Ruri\|Sakamoto, Nozomi\|Fukumoto, Keisuke\|Nomoto, Akihiro\|Kawamoto, Keisuke\|Shibahara, Takashi\|Yamaguchi, Hideki\|Sakai, Ryuichi
PMID:	28256037

276.
Journal:	Mol Carcinog. 2017 Aug;56(8):1884-1895.
Title:	Loss of desmoglein 2 promotes tumorigenic behavior in pancreatic cancer cells.
Author:	Hutz, Katharina\|Zeiler, Julian\|Sachs, Lena\|Ormanns, Steffen\|Spindler, Volker
PMID:	28277619

277.
Journal:	Int J Oncol. 2017 May;50(5):1792-1800.
Title:	A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
Author:	Liu, Wensheng\|Zhang, Bo\|Hu, Qiangsheng\|Qin, Yi\|Xu, Wenyan\|Shi, Si\|Liang, Chen\|Meng, Qingcai\|Xiang, Jinfeng\|Liang, Dingkong\|Ji, Shunrong\|Liu, Jiang\|Hu, Pengfei\|Liu, Liang\|Liu, Chen\|Long, Jiang\|Ni, Quanxing\|Yu, Xianjun\|Xu, Jin
PMID:	28350132

278.
Journal:	PLoS One. 2017 May 5;12(5):e0176844.
Title:	LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Author:	Ma, Lixiang\|Saiyin, Hexige
PMID:	28475592

279.
Journal:	Cancers (Basel). 2017 May 17;9(5). pii: cancers9050052.
Title:	Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways.
Author:	Wee, Ping\|Wang, Zhixiang
PMID:	28513565

280.
Journal:	DNA Cell Biol. 2017 Aug;36(8):619-626.
Title:	miR-144-3p Induces Cell Cycle Arrest and Apoptosis in Pancreatic Cancer Cells by Targeting Proline-Rich Protein 11 Expression via the Mitogen-Activated Protein Kinase Signaling Pathway.
Author:	Li, Jian\|Sun, Peisheng\|Yue, Zhongyi\|Zhang, Dezhong\|You, Kun\|Wang, Jianguo
PMID:	28574724

281.
Journal:	Oncotarget. 2017 Jul 4;8(27):44295-44311.
Title:	Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.
Author:	Ning, Changwen\|Liang, Min\|Liu, Shuang\|Wang, Guan\|Edwards, Holly\|Xia, Yang\|Polin, Lisa\|Dyson, Gregory\|Taub, Jeffrey W\|Mohammad, Ramzi M\|Azmi, Asfar S\|Zhao, Lijing\|Ge, Yubin
PMID:	28574828

282.
Journal:	Br J Cancer. 2017 Jul 11;117(2):245-255.
Title:	KIF15 promotes pancreatic cancer proliferation via the MEK-ERK signalling pathway.
Author:	Wang, Jie\|Guo, Xingjun\|Xie, Chencheng\|Jiang, Jianxin
PMID:	28595260

283.
Journal:	Mol Cancer Ther. 2017 Sep;16(9):1729-1738.
Title:	Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma.
Author:	Sahu, Nisebita\|Chan, Emily\|Chu, Felix\|Pham, Thinh\|Koeppen, Hartmut\|Forrest, William\|Merchant, Mark\|Settleman, Jeff
PMID:	28619758

284.
Journal:	Small GTPases. 2017 Jun 28:1-8.
Title:	Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition.
Author:	Kent, Oliver A\|Sandi, Maria-Jose\|Rottapel, Robert
PMID:	28656876

285.
Journal:	J Exp Clin Cancer Res. 2017 Jul 3;36(1):91.
Title:	In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer.
Author:	Fujita, Megumi\|Hasegawa, Ai\|Yamamori, Motohiro\|Okamura, Noboru
PMID:	28673319

286.
Journal:	Clin Cancer Res. 2017 Oct 1;23(19):5892-5911.
Title:	Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral env RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth.
Author:	Li, Ming\|Radvanyi, Laszlo\|Yin, Bingnan\|Li, Jia\|Chivukula, Raghavender\|Lin, Kevin\|Lu, Yue\|Shen, JianJun\|Chang, David Z\|Li, Donghui\|Johanning, Gary L\|Wang-Johanning, Feng
PMID:	28679769

287.
Journal:	Mol Cell Biol. 2017 Jul 10. pii: MCB.00132-17.
Title:	Phosphorylation of the C-Raf N-region promotes Raf dimerization.
Author:	Takahashi, Maho\|Li, Yanping\|Dillon, Tara J\|Kariya, Yumi\|Stork, Philip J S
PMID:	28694330

288.
Journal:	Biomacromolecules. 2017 Aug 14;18(8):2247-2257.
Title:	Chloroquine-Modified Hydroxyethyl Starch as a Polymeric Drug for Cancer Therapy.
Author:	Sleightholm, Richard\|Yang, Bin\|Yu, Fei\|Xie, Ying\|Oupicky, David
PMID:	28708385

289.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Jul;33(7):920-925.
Title:	[Expressions of stem cell factor and hypoxia inducible factor 1 alpha in pancreatic cancer cells and related mechanism].
Author:	Zhang, Min\|Wang, Yunjian\|Li, Qiong\|Li, Qingjun\|Yang, Nanmu\|You, Guohua\|Wang, Li
PMID:	28712399

290.
Journal:	Cancer Res. 2017 Aug 15;77(16):4328-4341.
Title:	Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction.
Author:	Jin, Xin\|Pan, Yunqian\|Wang, Liguo\|Ma, Tao\|Zhang, Lizhi\|Tang, Amy H\|Billadeau, Daniel D\|Wu, Heshui\|Huang, Haojie
PMID:	28720574

291.
Journal:	BMC Cancer. 2017 Jul 21;17(1):495.
Title:	Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer.
Author:	Quadri, Humair S\|Aiken, Taylor J\|Allgaeuer, Michael\|Moravec, Radim\|Altekruse, Sean\|Hussain, S Perwez\|Miettinen, Markku M\|Hewitt, Stephen M\|Rudloff, Udo
PMID:	28732488

292.
Journal:	Int J Cancer. 2017 Nov 15;141(10):2131-2142.
Title:	GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.
Author:	Bernier, Michel\|Catazaro, Jonathan\|Singh, Nagendra S\|Wnorowski, Artur\|Boguszewska-Czubara, Anna\|Jozwiak, Krzysztof\|Powers, Robert\|Wainer, Irving W
PMID:	28741686

293.
Journal:	Cell Rep. 2017 Jul 25;20(4):999-1015.
Title:	A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Author:	Anderson, Grace R\|Winter, Peter S\|Lin, Kevin H\|Nussbaum, Daniel P\|Cakir, Merve\|Stein, Elizabeth M\|Soderquist, Ryan S\|Crawford, Lorin\|Leeds, Jim C\|Newcomb, Rachel\|Stepp, Priya\|Yip, Catherine\|Wardell, Suzanne E\|Tingley, Jennifer P\|Ali, Moiez\|Xu, Mengmeng\|Ry
PMID:	28746882

294.
Journal:	Biochem Biophys Res Commun. 2017 Nov 4;493(1):592-597.
Title:	RAGE maintains high levels of NFkappaB and oncogenic Kras activity in pancreatic cancer.
Author:	Azizan, Nancy\|Suter, Melissa A\|Liu, Yan\|Logsdon, Craig D
PMID:	28867179

295.
Journal:	J Exp Clin Cancer Res. 2017 Sep 11;36(1):124.
Title:	Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells.
Author:	Xu, Zihang\|Zhang, Fei\|Bai, Chao\|Yao, Chao\|Zhong, Hairong\|Zou, Chunpu\|Chen, Xiao
PMID:	28893319

296.
Journal:	J Biol Chem. 2017 Oct 27;292(43):17681-17702.
Title:	The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells.
Author:	Tsuboi, Makiko\|Taniuchi, Keisuke\|Shimizu, Takahiro\|Saito, Motoaki\|Saibara, Toshiji
PMID:	28912272

297.
Journal:	Oncotarget. 2017 Apr 7;8(34):56351-56363.
Title:	Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways.
Author:	Zhou, Rong-Tao\|He, Mei\|Yu, Ze\|Liang, Yang\|Nie, Yuzhe\|Tai, Sheng\|Teng, Chun-Bo
PMID:	28915595

298.
Journal:	Cancer Lett. 2017 Dec 28;411:44-56.
Title:	NEMO peptide inhibits the growth of pancreatic ductal adenocarcinoma by blocking NF-kappaB activation.
Author:	Zhuang, Zhuonan\|Li, Hao\|Lee, Harold\|Aguilar, Mitzi\|Gocho, Takashi\|Ju, Huaiqiang\|Iida, Tomonori\|Ling, Jianhua\|Fu, Jie\|Wu, Min\|Sun, Yichen\|Lu, Yu\|Chiao, Paul J
PMID:	28951128

299.
Journal:	Ann Clin Lab Sci. 2017 Sep;47(5):572-580.
Title:	Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line.
Author:	Chowdhury, Parimal
PMID:	29066484

300.
Journal:	Oncotarget. 2017 May 11;8(42):71672-71684.
Title:	Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells.
Author:	Tjomsland, Vegard\|Aasrum, Monica\|Christoffersen, Thoralf\|Gladhaug, Ivar P
PMID:	29069737

301.
Journal:	Cell Death Dis. 2017 Oct 26;8(10):e3147.
Title:	Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Author:	Sheng, Weiwei\|Chen, Chuanping\|Dong, Ming\|Wang, Guosen\|Zhou, Jianping\|Song, He\|Li, Yang\|Zhang, Jian\|Ding, Shuangning
PMID:	29072694

302.
Journal:	J Radiat Res. 2017 Nov 1;58(6):816-826.
Title:	The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells.
Author:	Tsubouchi, Kento\|Minami, Kazumasa\|Hayashi, Naoki\|Yokoyama, Yuhki\|Mori, Seiji\|Yamamoto, Hirofumi\|Koizumi, Masahiko
PMID:	29106581

303.
Journal:	Oncotarget. 2016 Aug 23;8(52):89552-89565.
Title:	Role of microenvironmental periostin in pancreatic cancer progression.
Author:	Liu, Yang\|Li, Fan\|Gao, Feng\|Xing, Lingxi\|Qin, Peng\|Liang, Xingxin\|Zhang, Jiajie\|Qiao, Xiaohui\|Lin, Lizhou\|Zhao, Qian\|Du, Lianfang
PMID:	29163770

304.
Journal:	Oncotarget. 2017 Oct 4;8(54):92667-92681.
Title:	Thioredoxin system-mediated regulation of mutant Kras associated pancreatic neoplasia and cancer.
Author:	Schultz, Michelle A\|Diaz, Andrew M\|Smite, Sharon\|Lay, Anna R\|DeCant, Brian\|McKinney, Ronald\|Mascarinas, Windel E\|Xia, Yinglin\|Neumann, Carola\|Bentrem, David\|Dawson, David W\|Grippo, Paul J
PMID:	29190947

305.
Journal:	Sci Rep. 2017 Dec 11;7(1):17313.
Title:	Negative regulation of TGF-beta1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b.
Author:	Witte, David\|Otterbein, Hannah\|Forster, Maria\|Giehl, Klaudia\|Zeiser, Robert\|Lehnert, Hendrik\|Ungefroren, Hendrik
PMID:	29229918

306.
Journal:	Oncotarget. 2017 Sep 22;8(59):99693-99706.
Title:	Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression.
Author:	Peng, Meiyu\|Zhang, Qi\|Cheng, Yingnan\|Fu, Shuyu\|Yang, Huipeng\|Guo, Xiangdong\|Zhang, Jieyou\|Wang, Lina\|Zhang, Lijuan\|Xue, Zhenyi\|Li, Yan\|Da, Yurong\|Yao, Zhi\|Qiao, Liang\|Zhang, Rongxin
PMID:	29245934

307.
Journal:	Oncotarget. 2017 Oct 9;8(61):103167-103181.
Title:	Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.
Author:	Zhou, Jingkai\|Zhao, Tiangang\|Ma, Linfeng\|Liang, Min\|Guo, Ying-Jie\|Zhao, Li-Mei
PMID:	29262554

308.
Journal:	Postepy Dermatol Alergol. 2017 Oct;34(5):418-428.
Title:	The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors.
Author:	Owczarek, Witold\|Slowinska, Monika\|Lesiak, Aleksandra\|Ciazynska, Magdalena\|Maciag, Aldona\|Paluchowska, Elwira\|Marek-Jozefowicz, Luiza\|Czajkowski, Rafal
PMID:	29507555

309.
Journal:	Clin Cancer Res. 2018 Jan 15;24(2):433-444.
Title:	Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.
Author:	Bartolome, Ruben A\|Aizpurua, Carmen\|Jaen, Marta\|Torres, Sofia\|Calvino, Eva\|Imbaud, Juan I\|Casal, J Ignacio
PMID:	28916526

310.
Journal:	Biochem Biophys Res Commun. 2018 Jan 1;495(1):71-77.
Title:	Exosomes derived from pancreatic cancer cells induce activation and profibrogenic activities in pancreatic stellate cells.
Author:	Masamune, Atsushi\|Yoshida, Naoki\|Hamada, Shin\|Takikawa, Tetsuya\|Nabeshima, Tatsuhide\|Shimosegawa, Tooru
PMID:	29111329

311.
Journal:	Int J Cancer. 2018 Jun 1;142(11):2323-2334.
Title:	KRAS promotes tumor metastasis and chemoresistance by repressing RKIP via the MAPK-ERK pathway in pancreatic cancer.
Author:	Yang, Kege\|Li, Yaqing\|Lian, Guoda\|Lin, Haoming\|Shang, Changzhen\|Zeng, Linjuan\|Chen, Shaojie\|Li, Jiajia\|Huang, Chumei\|Huang, Kaihong\|Chen, Yinting
PMID:	29315556

312.
Journal:	Mol Cell Proteomics. 2018 Apr;17(4):655-671.
Title:	Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-Scale, Ion-Current-Based Quantitative Proteomics (IonStar).
Author:	Wang, Xue\|Niu, Jin\|Li, Jun\|Shen, Xiaomeng\|Shen, Shichen\|Straubinger, Robert M\|Qu, Jun
PMID:	29358341

313.
Journal:	J Cell Commun Signal. 2018 Jan 29. pii: 10.1007/s12079-017-0444-0.
Title:	p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines.
Author:	Aasrum, Monica\|Thoresen, G Hege\|Christoffersen, Thoralf\|Brusevold, Ingvild J
PMID:	29380233

314.
Journal:	J Biol Chem. 2018 Mar 23;293(12):4334-4349.
Title:	The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling.
Author:	Maity, Gargi\|Haque, Inamul\|Ghosh, Arnab\|Dhar, Gopal\|Gupta, Vijayalaxmi\|Sarkar, Sandipto\|Azeem, Imaan\|McGregor, Douglas\|Choudhary, Abhishek\|Campbell, Donald R\|Kambhampati, Suman\|Banerjee, Sushanta K\|Banerjee, Snigdha
PMID:	29414775

315.
Journal:	Oncotarget. 2017 Dec 25;9(4):5274-5286.
Title:	Inhibition of the MEK/ERK pathway augments nab-paclitaxel-based chemotherapy effects in preclinical models of pancreatic cancer.
Author:	Awasthi, Niranjan\|Monahan, Sheena\|Stefaniak, Alexis\|Schwarz, Margaret A\|Schwarz, Roderich E
PMID:	29435178

316.
Journal:	Int J Oncol. 2018 Apr;52(4):1105-1116.
Title:	RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling.
Author:	Qi, Zi-Hao\|Xu, Hua-Xiang\|Zhang, Shi-Rong\|Xu, Jin-Zhi\|Li, Shuo\|Gao, He-Li\|Jin, Wei\|Wang, Wen-Quan\|Wu, Chun-Tao\|Ni, Quan-Xing\|Yu, Xian-Jun\|Liu, Liang
PMID:	29436617

317.
Journal:	Anal Biochem. 2018 May 1;548:44-52.
Title:	High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.
Author:	Burns, Michael C\|Howes, Jennifer E\|Sun, Qi\|Little, Andrew J\|Camper, DeMarco V\|Abbott, Jason R\|Phan, Jason\|Lee, Taekyu\|Waterson, Alex G\|Rossanese, Olivia W\|Fesik, Stephen W
PMID:	29444450

318.
Journal:	Oncotarget. 2018 Jan 8;9(6):6938-6951.
Title:	Spiclomazine displays a preferential anti-tumor activity in mutant KRas-driven pancreatic cancer.
Author:	Guo, Xiaoyu\|Zhao, Wenjing\|Liu, Zuojia\|Wang, Jin
PMID:	29467941

319.
Journal:	Cell Signal. 2018 Jul;47:101-108.
Title:	alpha-cyano-4-hydroxycinnamate impairs pancreatic cancer cells by stimulating the p38 signaling pathway.
Author:	Schonrogge, Maria\|Kerndl, Hagen\|Zhang, Xianbin\|Kumstel, Simone\|Vollmar, Brigitte\|Zechner, Dietmar
PMID:	29609037

320.
Journal:	Mol Carcinog. 2018 Sep;57(9):1130-1143.
Title:	A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras.
Author:	Mallangada, Naveen A\|Vargas, Joselin M\|Thomas, Swaroopa\|DiGiovanni, Matthew G\|Vaeth, Brandon M\|Nemesure, Matthew D\|Wang, Ruixue\|LaComb, Joseph F\|Williams, Jennie L\|Golub, Lorne M\|Johnson, Francis\|Mackenzie, Gerardo G
PMID:	29683208

321.
Journal:	Biochem Biophys Res Commun. 2018 Jun 12;500(4):873-878.
Title:	ROS mediated EGFR/MEK/ERK/HIF-1alpha Loop Regulates Glucose metabolism in pancreatic cancer.
Author:	Wang, Gang\|Li, Yifeng\|Yang, Zeyu\|Xu, Weina\|Yang, Yifan\|Tan, Xiaodong
PMID:	29702094

322.
Journal:	Cancer Lett. 2018 Sep 28;432:237-250.
Title:	Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer.
Author:	Li, Zhonghu\|Yanfang, Wu\|Li, Jie\|Jiang, Peng\|Peng, Tao\|Chen, Kai\|Zhao, Xin\|Zhang, Yujun\|Zhen, Ping\|Zhu, Jin\|Li, Xiaowu
PMID:	29709702

323.
Journal:	Int J Oncol. 2018 Jul;53(1):349-357.
Title:	Inhibition of interleukin 8/CX-C chemokine receptor 1,/2 signaling reduces malignant features in human pancreatic cancer cells.
Author:	Fu, Shengling\|Chen, Xiang\|Lin, Huey-Jen\|Lin, Jiayuh
PMID:	29749433

324.
Journal:	Cancers (Basel). 2018 May 14;10(5). pii: cancers10050142.
Title:	A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology.
Author:	Van Sciver, Robert E\|Lee, Michael P\|Lee, Caroline Dasom\|Lafever, Alex C\|Svyatova, Elizaveta\|Kanda, Kevin\|Colliver, Amber L\|Siewertsz van Reesema, Lauren L\|Tang-Tan, Angela M\|Zheleva, Vasilena\|Bwayi, Monicah N\|Bian, Minglei\|Schmidt, Rebecca L\|Matrisian, Ly
PMID:	29757973

325.
Journal:	Pol Przegl Chir. 2018 Apr 30;90(2):45-53.
Title:	Surgical treatment of pancreatic cancer.
Author:	Masiak-Segit, Wioletta\|Rawicz-Pruszynski, Karol\|Skorzewska, Magdalena\|Polkowski, Wojciech P
PMID:	29773761

326.
Journal:	Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2538-2549.
Title:	Axed MUC4 (MUC4/X) aggravates pancreatic malignant phenotype by activating integrin-beta1/FAK/ERK pathway.
Author:	Jahan, Rahat\|Macha, Muzafar A\|Rachagani, Satyanarayana\|Das, Srustidhar\|Smith, Lynette M\|Kaur, Sukhwinder\|Batra, Surinder K
PMID:	29777904

327.
Journal:	Nat Commun. 2018 May 25;9(1):2081.
Title:	In vivo reprogramming drives Kras-induced cancer development.
Author:	Shibata, Hirofumi\|Komura, Shingo\|Yamada, Yosuke\|Sankoda, Nao\|Tanaka, Akito\|Ukai, Tomoyo\|Kabata, Mio\|Sakurai, Satoko\|Kuze, Bunya\|Woltjen, Knut\|Haga, Hironori\|Ito, Yatsuji\|Kawaguchi, Yoshiya\|Yamamoto, Takuya\|Yamada, Yasuhiro
PMID:	29802314

328.
Journal:	Theranostics. 2018 Apr 30;8(11):3074-3086.
Title:	MMP1/PAR1/SP/NK1R paracrine loop modulates early perineural invasion of pancreatic cancer cells.
Author:	Huang, Chumei\|Li, Yaqing\|Guo, Yubo\|Zhang, Zuoquan\|Lian, Guoda\|Chen, Yinting\|Li, Jian\|Su, Yonghui\|Li, Jiajia\|Yang, Kege\|Chen, Shaojie\|Su, Hong\|Huang, Kaihong\|Zeng, Linjuan
PMID:	29896303

329.
Journal:	Cancer Lett. 2018 Oct 1;433:76-85.
Title:	Loss of Linc01060 induces pancreatic cancer progression through vinculin-mediated focal adhesion turnover.
Author:	Shi, Xiuhui\|Guo, Xingjun\|Li, Xu\|Wang, Min\|Qin, Renyi
PMID:	29913236

330.
Journal:	Theranostics. 2018 May 23;8(12):3366-3379.
Title:	Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine.
Author:	Huang, Xudong\|Zheng, Jian\|Li, Jun\|Che, Xu\|Tan, Wenle\|Tan, Wen\|Shao, Mingming\|Cheng, Xinxin\|Du, Zhongli\|Zhao, Yanjie\|Wang, Chengfeng\|Wu, Chen\|Lin, Dongxin
PMID:	29930735

331.
Journal:	Yonsei Med J. 2018 Aug;59(6):727-735.
Title:	Synergistic Anti-Cancer Effects of AKT and SRC Inhibition in Human Pancreatic Cancer Cells.
Author:	Ahn, Kang\|O, Young Moon\|Ji, Young Geon\|Cho, Han Jun\|Lee, Dong Hyeon
PMID:	29978609

332.
Journal:	Int J Mol Sci. 2018 Jul 9;19(7). pii: ijms19072004.
Title:	A Novel Monoclonal Antibody Targets Mucin1 and Attenuates Growth in Pancreatic Cancer Model.
Author:	Wu, Guang\|Maharjan, Sony\|Kim, Dongbum\|Kim, Jung Nam\|Park, Byoung Kwon\|Koh, Heeju\|Moon, Kyungduk\|Lee, Younghee\|Kwon, Hyung-Joo
PMID:	29987260

333.
Journal:	Endocr Relat Cancer. 2018 Jul 18. pii: ERC-18-0222.
Title:	The IGF pathway is activated in insulinomas but downregulated in metastatic disease.
Author:	Henfling, Mieke\|Perren, Aurel\|Schmitt, Anja Maria\|Saddig, Christiane M\|Starke, Achim A\|Riedl, Robert G\|Versleijen-Jonkers, Yvonne M H\|Sprij-Mooij, Diane M\|Ramaekers, Frans C S\|Hofland, Leo\|Speel, Ernst-Jan M
PMID:	30021864

334.
Journal:	Immunohorizons. 2018 Apr 1;2(4):107-118.
Title:	Diacylglycerol kinase zeta (DGKzeta) and Casitas b-lineage proto-oncogene b-deficient mice have similar functional outcomes in T cells but DGKzeta-deficient mice have increased T cell activation and tumor clearance.
Author:	Wesley, Erin M\|Xin, Gang\|McAllister, Donna\|Malarkannan, Subramaniam\|Newman, Debra K\|Dwinell, Michael B\|Cui, Weiguo\|Johnson, Bryon D\|Riese, Matthew J
PMID:	30027154

335.
Journal:	Cell Death Dis. 2018 Jul 23;9(8):804.
Title:	Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis.
Author:	Akimoto, Miho\|Maruyama, Riruke\|Kawabata, Yasunari\|Tajima, Yoshitsugu\|Takenaga, Keizo
PMID:	30038429

336.
Journal:	J Exp Clin Cancer Res. 2018 Jul 24;37(1):166.
Title:	Transgelin-2 is a novel target of KRAS-ERK signaling involved in the development of pancreatic cancer.
Author:	Sun, Yan\|Peng, Wenfang\|He, Weiwei\|Luo, Man\|Chang, Guilin\|Shen, Jiping\|Zhao, Xiaoping\|Hu, Yu
PMID:	30041673

337.
Journal:	Cell Death Dis. 2018 Jul 24;9(8):807.
Title:	MiR-361-3p regulates ERK1/2-induced EMT via DUSP2 mRNA degradation in pancreatic ductal adenocarcinoma.
Author:	Hu, Jisheng\|Li, Le\|Chen, Hongze\|Zhang, Guangquan\|Liu, Huan\|Kong, Rui\|Chen, Hua\|Wang, Yongwei\|Li, Yilong\|Tian, Fengyu\|Lv, Xinjian\|Li, Guanqun\|Sun, Bei
PMID:	30042387

338.
Journal:	Pancreatology. 2018 Sep;18(6):678-688.
Title:	Knockdown of AGR2 induces cell apoptosis and reduces chemotherapy resistance of pancreatic cancer cells with the involvement of ERK/AKT axis.
Author:	Liu, Qing-Guo\|Li, Yan-Ju\|Yao, Lan
PMID:	30055941

339.
Journal:	Mol Cancer Ther. 2018 Jul 31. pii: 1535-7163.MCT-17-1142.
Title:	Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models.
Author:	Jiang, Hongmei\|Xu, Mai\|Li, Lin\|Grierson, Patrick\|Dodhiawala, Paarth\|Highkin, Maureen\|Zhang, Daoxiang\|Li, Qiong\|Wang-Gillam, Andrea\|Lim, Kian-Huat
PMID:	30065098

340.
Journal:	Cancer Biol Ther. 2018 Aug 24:1-13.
Title:	Prior exposure of pancreatic tumors to [sorafenib + vorinostat] enhances the efficacy of an anti-PD-1 antibody.
Author:	Booth, Laurence\|Roberts, Jane Lisa\|Poklepovic, Andrew\|Dent, Paul
PMID:	30142009

341.
Journal:	Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0634.
Title:	Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
Author:	Nagathihalli, Nagaraj S\|Castellanos, Jason\|Lamichhane, Purushottam\|Messaggio, Fanuel\|Shi, Chanjuan\|Dai, Xizi\|Rai, Priyamvada\|Chen, Xi\|VanSaun, Michael N\|Merchant, Nipun B
PMID:	30154150

342.
Journal:	J Exp Clin Cancer Res. 2018 Sep 10;37(1):224.
Title:	FBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma.
Author:	Wang, Bo\|Fan, Ping\|Zhao, Jingyuan\|Wu, Heyu\|Jin, Xin\|Wu, Heshui
PMID:	30201002

343.
Journal:	Pancreatology. 2018 Aug 24. pii: S1424-3903(18)30645-8.
Title:	The radiotherapy-sensitization effect of cantharidin: Mechanisms involving cell cycle regulation, enhanced DNA damage, and inhibited DNA damage repair.
Author:	Xu, Meng-Dan\|Liu, Shu-Ling\|Zheng, Bei-Bei\|Wu, Jing\|Wu, Meng-Yao\|Zhang, Yan\|Gong, Fei-Ran\|Tao, Min\|Zhang, Junning\|Li, Wei
PMID:	30201439

344.
Journal:	Cancer Lett. 2018 Sep 11;438:174-186.
Title:	KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer.
Author:	Kang, Yeo Wool\|Lee, Ji Eun\|Jung, Kyung Hee\|Son, Mi Kwon\|Shin, Seung-Min\|Kim, Soo Jung\|Fang, Zhenghuan\|Yan, Hong Hua\|Park, Jung Hee\|Han, Boreum\|Cheon, Min Ji\|Woo, Min Gyu\|Lim, Joo Han\|Kim, Yong-Sung\|Hong, Soon-Sun
PMID:	30217561

345.
Journal:	Oncol Rep. 2018 Nov;40(5):3102-3111.
Title:	Tanshinone IIA can inhibit MiaPaCa2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways.
Author:	Su, Chin-Cheng
PMID:	30226540

346.
Journal:	Mol Ther Nucleic Acids. 2018 Aug 22;13:121-132.
Title:	miR-7 Suppresses Tumor Progression by Directly Targeting MAP3K9 in Pancreatic Cancer.
Author:	Xia, Jun\|Cao, Tong\|Ma, Cong\|Shi, Ying\|Sun, Yu\|Wang, Z Peter\|Ma, Jia
PMID:	30290304

347.
Journal:	Mol Cell Biochem. 2018 Oct 11. pii: 10.1007/s11010-018-3455-0.
Title:	C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Author:	Li, Xin\|Dong, Ming\|Zhou, Jianping\|Zhu, Dehua\|Zhao, Jinbo\|Sheng, Weiwei
PMID:	30311108

348.
Journal:	Cancer Res. 2018 Oct 24. pii: 0008-5472.CAN-18-1968.
Title:	PIN1 maintains redox balance via the c-Myc/NRF2 axis to counteract Kras-induced mitochondrial respiratory injury in pancreatic cancer cells.
Author:	Liang, Chen\|Shi, Si\|Liu, Mingyang\|Qin, Yi\|Meng, Qingcai\|Hua, Jie\|Ji, Shunrong\|Zhang, Yuqing\|Yang, Jingxuan\|Xu, Jin\|Ni, Quanxing\|Li, Min\|Yu, Xianjun
PMID:	30355620