Literatures

Primary Site >> Liver Cancer

Gene >> EPHB2

1.
Journal:	J Clin Invest. 1993 Nov;92(5):2419-26.
Title:	Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma.
Author:	Imai, H\|Chan, E K\|Kiyosawa, K\|Fu, X D\|Tan, E M
PMID:	8227358

2.
Journal:	Hepatology. 1998 Apr;27(4):951-8.
Title:	Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma.
Author:	Ito, Y\|Sasaki, Y\|Horimoto, M\|Wada, S\|Tanaka, Y\|Kasahara, A\|Ueki, T\|Hirano, T\|Yamamoto, H\|Fujimoto, J\|Okamoto, E\|Hayashi, N\|Hori, M
PMID:	9537433

3.
Journal:	Hepatology. 2000 Nov;32(5):958-61.
Title:	Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha.
Author:	Hayashi, J\|Aoki, H\|Kajino, K\|Moriyama, M\|Arakawa, Y\|Hino, O
PMID:	11050045

4.
Journal:	Arch Pharm Res. 2000 Dec;23(6):605-12.
Title:	Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death.
Author:	Chen, C\|Yu, R\|Owuor, E D\|Kong, A N
PMID:	11156183

5.
Journal:	Int J Oncol. 2001 Jun;18(6):1271-8.
Title:	Genetic and epigenetic events in human hepatocarcinogenesis.
Author:	Kondoh, N\|Wakatsuki, T\|Hada, A\|Shuda, M\|Tanaka, K\|Arai, M\|Yamamoto, M
PMID:	11351262

6.
Journal:	Cancer Res. 2001 Jul 1;61(13):5016-23.
Title:	Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?
Author:	Yang, S\|Lin, H Z\|Hwang, J\|Chacko, V P\|Diehl, A M
PMID:	11431335

7.
Journal:	Hum Mol Genet. 2001 Aug 15;10(17):1741-52.
Title:	Fumarylacetoacetate, the metabolite accumulating in hereditary tyrosinemia, activates the ERK pathway and induces mitotic abnormalities and genomic instability.
Author:	Jorquera, R\|Tanguay, R M
PMID:	11532983

8.
Journal:	J Biol Chem. 2001 Nov 2;276(44):40968-76.
Title:	High intensity ERK signal mediates hepatocyte growth factor-induced proliferation inhibition of the human hepatocellular carcinoma cell line HepG2.
Author:	Tsukada, Y\|Miyazawa, K\|Kitamura, N
PMID:	11533045

9.
Journal:	J Virol. 2001 Nov;75(21):10348-58.
Title:	Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.
Author:	Nijhara, R\|Jana, S S\|Goswami, S K\|Rana, A\|Majumdar, S S\|Kumar, V\|Sarkar, D P
PMID:	11581403

10.
Journal:	Cancer. 2002 Feb 15;94(4):934-9.
Title:	Coexpression of ephrin-Bs and their receptors in colon carcinoma.
Author:	Liu, Wenbiao\|Ahmad, Syed A\|Jung, Young D\|Reinmuth, Niels\|Fan, Fan\|Bucana, Corazon D\|Ellis, Lee M
PMID:	11920461

11.
Journal:	Cancer. 2002 Aug 15;95(4):896-906.
Title:	Beta 1-integrin protects hepatoma cells from chemotherapy induced apoptosis via a mitogen-activated protein kinase dependent pathway.
Author:	Zhang, Hao\|Ozaki, Iwata\|Mizuta, Toshihiko\|Matsuhashi, Sachiko\|Yoshimura, Tohru\|Hisatomi, Akitaka\|Tadano, Jutaro\|Sakai, Takahiro\|Yamamoto, Kyosuke
PMID:	12209735

12.
Journal:	Gut. 2003 May;52(5):706-12.
Title:	Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma.
Author:	Tannapfel, A\|Sommerer, F\|Benicke, M\|Katalinic, A\|Uhlmann, D\|Witzigmann, H\|Hauss, J\|Wittekind, C
PMID:	12692057

13.
Journal:	Biochem Biophys Res Commun. 2003 May 30;305(2):428-33.
Title:	An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells.
Author:	Hah, Nasun\|Lee, Seung-Taek
PMID:	12745093

14.
Journal:	J Hepatol. 2003 Jun;38(6):803-10.
Title:	Constitutive over-expression of the insulin receptor substrate-1 causes functional up-regulation of Fas receptor.
Author:	Wiedmann, Marcus\|Tamaki, Seishu\|Silberman, Rebecca\|de la Monte, Suzanne M\|Cousens, Leslie\|Wands, Jack R
PMID:	12763374

15.
Journal:	J Gastrointest Surg. 2003 Dec;7(8):1024-33.
Title:	Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis.
Author:	Schmidt, C Max\|Wang, Yufang\|Wiesenauer, Chad
PMID:	14675712

16.
Journal:	Clin Chem. 2004 Mar;50(3):490-9.
Title:	Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers.
Author:	Hafner, Christian\|Schmitz, Gerd\|Meyer, Stefanie\|Bataille, Frauke\|Hau, Peter\|Langmann, Thomas\|Dietmaier, Wolfgang\|Landthaler, Michael\|Vogt, Thomas
PMID:	14726470

17.
Journal:	J Am Coll Surg. 2004 Mar;198(3):410-21.
Title:	Multiple anticancer effects of blocking MEK-ERK signaling in hepatocellular carcinoma.
Author:	Wiesenauer, Chad A\|Yip-Schneider, Michele T\|Wang, Yufang\|Schmidt, C Max
PMID:	14992744

18.
Journal:	FASEB J. 2004 May;18(7):914-6.
Title:	Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.
Author:	Chen, Lixin\|Zeng, Ying\|Yang, Heping\|Lee, Taunia D\|French, Samuel W\|Corrales, Fernando J\|Garcia-Trevijano, Elena R\|Avila, Matias A\|Mato, Jose M\|Lu, Shelly C
PMID:	15033934

19.
Journal:	Mol Cancer Res. 2004 Mar;2(3):159-69.
Title:	Mitotic aberration coupled with centrosome amplification is induced by hepatitis B virus X oncoprotein via the Ras-mitogen-activated protein/extracellular signal-regulated kinase-mitogen-activated protein pathway.
Author:	Yun, Chawon\|Cho, Hyeseon\|Kim, Su-Jeong\|Lee, Jae-Ho\|Park, Sun Yi\|Chan, Gordon K\|Cho, Hyeseong
PMID:	15037655

20.
Journal:	FASEB J. 2004 Jul;18(10):1123-5.
Title:	Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential.
Author:	Chung, Tae-Wook\|Lee, Young-Choon\|Kim, Cheorl-Ho
PMID:	15132991

21.
Journal:	Mol Immunol. 2004 Jul;41(9):847-54.
Title:	Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells.
Author:	Schauber, Jurgen\|Iffland, Konrad\|Frisch, Susanne\|Kudlich, Theodor\|Schmausser, Bernd\|Eck, Matthias\|Menzel, Thomas\|Gostner, Andrea\|Luhrs, Hardi\|Scheppach, Wolfgang
PMID:	15261456

22.
Journal:	J Hepatol. 2004 Aug;41(2):274-83.
Title:	Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): a novel mechanism for tumor invasion.
Author:	Schmitt, Marcus\|Horbach, Axel\|Kubitz, Ralf\|Frilling, Andrea\|Haussinger, Dieter
PMID:	15288477

23.
Journal:	Cancer Sci. 2004 Aug;95(8):666-73.
Title:	Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines.
Author:	Cheng, Jidong\|Imanishi, Hiroyasu\|Liu, Weidong\|Nakamura, Hideji\|Morisaki, Takayuki\|Higashino, Kazuya\|Hada, Toshikazu
PMID:	15298730

24.
Journal:	Hepatology. 2004 Sep;40(3):618-28.
Title:	Negative regulation of hepatocellular carcinoma cell growth by signal regulatory protein alpha1.
Author:	Yan, He-Xin\|Wang, Hong-Yang\|Zhang, Rui\|Chen, Lei\|Li, Bao-An\|Liu, Shu-Qin\|Cao, Hui-Fang\|Qiu, Xiu-Hua\|Shan, Yun-Feng\|Yan, Zhong-Hua\|Wu, Hong-Ping\|Tan, Ye-Xiong\|Wu, Meng-Chao
PMID:	15349900

25.
Journal:	J Hepatol. 2004 Oct;41(4):538-44.
Title:	Up-regulation of the high-affinity pyrimidine-preferring nucleoside transporter concentrative nucleoside transporter 1 by tumor necrosis factor-alpha and interleukin-6 in liver parenchymal cells.
Author:	Fernandez-Veledo, Sonia\|Valdes, Raquel\|Wallenius, Ville\|Casado, F Javier\|Pastor-Anglada, Marcal
PMID:	15464233

26.
Journal:	Liver Int. 2004 Oct;24(5):432-6.
Title:	Overexpression of extracellular signal-regulated protein kinase and its correlation with proliferation in human hepatocellular carcinoma.
Author:	Tsuboi, Yasunori\|Ichida, Takafumi\|Sugitani, Soichi\|Genda, Takuya\|Inayoshi, Jun\|Takamura, Masaaki\|Matsuda, Yasunobu\|Nomoto, Minoru\|Aoyagi, Yutaka
PMID:	15482339

27.
Journal:	Int J Oncol. 2004 Dec;25(6):1839-47.
Title:	Extracellular signal-regulated kinase induces cyclin D1 and Cdk-2 expression and phosphorylation of retinoblastoma in hepatocellular carcinoma.
Author:	Huynh, H\|Do, P T\|Nguyen, T H\|Chow, P\|Tan, P H\|Quach, T H\|Van, T\|Soo, K C\|Tran, E
PMID:	15547725

28.
Journal:	J Biochem. 2004 Nov;136(5):701-9.
Title:	Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.
Author:	Tsukada, Yu-ichi\|Tanaka, Toshiaki\|Miyazawa, Keiji\|Kitamura, Naomi
PMID:	15632311

29.
Journal:	J Cell Physiol. 2005 Jun;203(3):510-9.
Title:	Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.
Author:	Wang, Ziqiu\|Wang, Meifang\|Carr, Brian I
PMID:	15534860

30.
Journal:	J Clin Oncol. 2005 Feb 10;23(5):965-72.
Title:	Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.
Author:	Strumberg, Dirk\|Richly, Heike\|Hilger, Ralf A\|Schleucher, Norbert\|Korfee, Sonke\|Tewes, Mitra\|Faghih, Markus\|Brendel, Erich\|Voliotis, Dimitris\|Haase, Claus G\|Schwartz, Brian\|Awada, Ahmad\|Voigtmann, Rudolf\|Scheulen, Max E\|Seeber, Siegfried
PMID:	15613696

31.
Journal:	Carcinogenesis. 2005 Apr;26(4):753-61.
Title:	Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells.
Author:	Mayoral, Rafael\|Fernandez-Martinez, Amalia\|Bosca, Lisardo\|Martin-Sanz, Paloma
PMID:	15661807

32.
Journal:	Arch Biochem Biophys. 2005 Apr 15;436(2):285-96.
Title:	Repression of 5-aminolevulinate synthase gene by the potent tumor promoter, TPA, involves multiple signal transduction pathways.
Author:	Guberman, Alejandra S\|Scassa, Maria E\|Canepa, Eduardo T
PMID:	15797241

33.
Journal:	Mol Cancer Ther. 2005 Apr;4(4):595-602.
Title:	Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.
Author:	Peyregne, Vincent P\|Kar, Siddhartha\|Ham, Seung W\|Wang, Meifang\|Wang, Ziqiu\|Carr, Brian I
PMID:	15827333

34.
Journal:	Life Sci. 2005 Jun 3;77(3):252-65.
Title:	Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells.
Author:	Li, Chyi-Hann\|Chen, Pei-Yu\|Chang, Ue-Min\|Kan, Lou-Sing\|Fang, Woei-Horng\|Tsai, Keh-Sung\|Lin, Shwu-Bin
PMID:	15878354

35.
Journal:	Arch Biochem Biophys. 2005 Jun 1;438(1):36-52.
Title:	Transcriptional activation of the Egr-1 gene mediated by tetradecanoylphorbol acetate and extracellular signal-regulated protein kinase.
Author:	Bauer, Inge\|Hohl, Mathias\|Al-Sarraj, Alia\|Vinson, Charles\|Thiel, Gerald
PMID:	15910736

36.
Journal:	J Biomed Sci. 2005;12(2):289-96.
Title:	Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2.
Author:	Wen-Sheng, Wu\|Jun-Ming, Huang
PMID:	15917995

37.
Journal:	Biochem Pharmacol. 2005 Jul 15;70(2):229-41.
Title:	Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway.
Author:	Su, Yu-Ting\|Chang, Huei-Ling\|Shyue, Song-Kun\|Hsu, Shih-Lan
PMID:	15941563

38.
Journal:	J Biol Chem. 2005 Sep 9;280(36):31548-56.
Title:	Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells.
Author:	Han, Junhong\|Tsukada, Yu-ichi\|Hara, Eiji\|Kitamura, Naomi\|Tanaka, Toshiaki
PMID:	16014626

39.
Journal:	Mol Cell. 2005 Jul 22;19(2):159-70.
Title:	Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Author:	Ding, Qingqing\|Xia, Weiya\|Liu, Jaw-Ching\|Yang, Jer-Yen\|Lee, Dung-Fang\|Xia, Jiahong\|Bartholomeusz, Geoffrey\|Li, Yan\|Pan, Yong\|Li, Zheng\|Bargou, Ralf C\|Qin, Jun\|Lai, Chien-Chen\|Tsai, Fuu-Jen\|Tsai, Chang-Hai\|Hung, Mien-Chie
PMID:	16039586

40.
Journal:	Cancer Biol Ther. 2005 Aug;4(8):874-82.
Title:	PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.
Author:	Tian, Fang\|Zhang, Xiongwen\|Tong, Yunguang\|Yi, Yanghua\|Zhang, Shilong\|Li, Ling\|Sun, Peng\|Lin, Liping\|Ding, Jian
PMID:	16082187

41.
Journal:	Ai Zheng. 2005 Aug;24(8):965-9.
Title:	[Effect of HBV X gene transfection on octreotide-inhibited growth of hepatocellular carcinoma cell line HepG2].
Author:	Xie, Yi\|Tang, Cheng-Wei\|Wang, Chun-Hui
PMID:	16086874

42.
Journal:	Cancer Lett. 2005 Dec 18;230(2):260-70.
Title:	DNA damage and G2/M arrest in Syrian hamster embryo cells during Malachite green exposure are associated with elevated phosphorylation of ERK1 and JNK1.
Author:	Bose, Bipasha\|Motiwale, Leena\|Rao, K V K
PMID:	16297712

43.
Journal:	Toxicol Appl Pharmacol. 2006 Jan 1;210(1-2):55-62.
Title:	Enhancement of esculetin on Taxol-induced apoptosis in human hepatoma HepG2 cells.
Author:	Kuo, Hsing-Chun\|Lee, Herng-Jiun\|Hu, Chao-Chin\|Shun, Han-I\|Tseng, Tsui-Hwa
PMID:	16051289

44.
Journal:	Food Chem Toxicol. 2006 Feb;44(2):227-35.
Title:	Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1).
Author:	Liu, Tsan-Zon\|Chen, Chung-Yi\|Yiin, Shuenn-Jiun\|Chen, Ching-Hsein\|Cheng, Jiin-Tsuey\|Shih, Ming-Kuei\|Wang, Yu-Shan\|Chern, Chi-Liang
PMID:	16112786

45.
Journal:	Cancer Lett. 2006 Jul 28;239(1):27-35.
Title:	Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
Author:	Wen-Sheng, Wu
PMID:	16169661

46.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G624-32.
Title:	Cell proliferation and drug resistance in hepatocellular carcinoma are modulated by Rho GTPase signals.
Author:	Sterpetti, Paola\|Marucci, Luca\|Candelaresi, Cinzia\|Toksoz, Deniz\|Alpini, Gianfranco\|Ugili, Laura\|Baroni, Gianluca Svegliati\|Macarri, Giampiero\|Benedetti, Antonio
PMID:	16322093

47.
Journal:	Int J Oncol. 2006 Jan;28(1):25-32.
Title:	Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma.
Author:	Fleischer, Binje\|Schulze-Bergkamen, Henning\|Schuchmann, Marcus\|Weber, Achim\|Biesterfeld, Stefan\|Muller, Martina\|Krammer, Peter H\|Galle, Peter R
PMID:	16327976

48.
Journal:	Chem Biol Interact. 2006 Mar 25;160(2):123-33.
Title:	Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways.
Author:	Lee, Wei-Jiunn\|Wu, Lan-Feng\|Chen, Wen-Kang\|Wang, Chau-Jong\|Tseng, Tsui-Hwa
PMID:	16458870

49.
Journal:	Cancer Lett. 2006 Oct 28;242(2):141-50.
Title:	Sprouty and cancer: the first terms report.
Author:	Lo, Ting Ling\|Fong, Chee Wai\|Yusoff, Permeen\|McKie, Arthur B\|Chua, Mei-Sze\|Leung, Hing Y\|Guy, Graeme R
PMID:	16469433

50.
Journal:	Neoplasia. 2006 Jan;8(1):1-8.
Title:	The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer.
Author:	Klein, Patrick J\|Schmidt, C Max\|Wiesenauer, Chad A\|Choi, Jennifer N\|Gage, Earl A\|Yip-Schneider, Michele T\|Wiebke, Eric A\|Wang, Yufang\|Omer, Charles\|Sebolt-Leopold, Judith S
PMID:	16533420

51.
Journal:	J Hepatol. 2006 May;44(5):971-83.
Title:	Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness.
Author:	de la Monte, Suzanne M\|Tamaki, Seishu\|Cantarini, M Chiara\|Ince, Nedim\|Wiedmann, Marcus\|Carter, Jade J\|Lahousse, Stephanie A\|Califano, Sophia\|Maeda, Takashi\|Ueno, Takato\|D'Errico, Antonia\|Trevisani, Franco\|Wands, Jack R
PMID:	16564107

52.
Journal:	Gut. 2006 Dec;55(12):1801-8.
Title:	Hepatitis C virus core protein promotes proliferation of human hepatoma cells through enhancement of transforming growth factor alpha expression via activation of nuclear factor-kappaB.
Author:	Sato, Y\|Kato, J\|Takimoto, R\|Takada, K\|Kawano, Y\|Miyanishi, K\|Kobune, M\|Sato, Y\|Takayama, T\|Matunaga, T\|Niitsu, Y
PMID:	16581947

53.
Journal:	Methods Enzymol. 2006;407:597-612.
Title:	Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature.
Author:	Adnane, Lila\|Trail, Pamela A\|Taylor, Ian\|Wilhelm, Scott M
PMID:	16757355

54.
Journal:	Gastroenterology. 2006 Jun;130(7):2130-44.
Title:	SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma.
Author:	Lai, Jin-Ping\|Yu, Chunrong\|Moser, Catherine D\|Aderca, Ileana\|Han, Tao\|Garvey, Thomas D\|Murphy, Linda M\|Garrity-Park, Megan M\|Shridhar, Viji\|Adjei, Alex A\|Roberts, Lewis R
PMID:	16762634

55.
Journal:	Nihon Rinsho. 2006 Jun;64(6):1033-42.
Title:	[Hepatocyte-specific Pten deficient mice].
Author:	Horie, Yasuo\|Ohshima, Shigetoshi\|Sato, Wataru\|Suzuki, Akira\|Watanabe, Sumio
PMID:	16768106

56.
Journal:	Arch Biochem Biophys. 2006 Aug 15;452(2):138-48.
Title:	The binding between p67 and eukaryotic initiation factor 2 plays important roles in the protection of eIF2alpha from phosphorylation by kinases.
Author:	Datta, Bansidhar\|Datta, Rekha\|Ghosh, Arnab\|Majumdar, Avijit
PMID:	16843428

57.
Journal:	Oncol Rep. 2006 Sep;16(3):451-6.
Title:	Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma.
Author:	Schuierer, Marion M\|Bataille, Frauke\|Weiss, Thomas S\|Hellerbrand, Claus\|Bosserhoff, Anja K
PMID:	16865242

58.
Journal:	Biochem Pharmacol. 2006 Nov 15;72(10):1217-27.
Title:	Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK.
Author:	Kar, Siddhartha\|Wang, Meifang\|Ham, Seung Wook\|Carr, Brian I
PMID:	16930563

59.
Journal:	Gastroenterology. 2006 Oct;131(4):1208-17.
Title:	Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells.
Author:	Lee, Han Chu\|Tian, Bo\|Sedivy, John M\|Wands, Jack R\|Kim, Miran
PMID:	17030190

60.
Journal:	Mol Cells. 2006 Dec 31;22(3):291-9.
Title:	Vitexin, an HIF-1alpha inhibitor, has anti-metastatic potential in PC12 cells.
Author:	Choi, Hwa Jung\|Eun, Jae Soon\|Kim, Bang Geul\|Kim, Sun Yeou\|Jeon, Hoon\|Soh, Yunjo
PMID:	17202857

61.
Journal:	J Cell Physiol. 2007 Mar;210(3):766-73.
Title:	Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells.
Author:	Yang, Heping\|Magilnick, Nathaniel\|Noureddin, Mazen\|Mato, Jose M\|Lu, Shelly C
PMID:	17154373

62.
Journal:	Liver Int. 2007 Mar;27(2):155-62.
Title:	Survival and apoptosis: a dysregulated balance in liver cancer.
Author:	Fabregat, Isabel\|Roncero, Cesar\|Fernandez, Margarita
PMID:	17311609

63.
Journal:	J Cell Physiol. 2007 Jun;211(3):699-707.
Title:	Thrombin-mediated hepatocellular carcinoma cell migration: cooperative action via proteinase-activated receptors 1 and 4.
Author:	Kaufmann, Roland\|Rahn, Stephanie\|Pollrich, Kristin\|Hertel, Julia\|Dittmar, Yves\|Hommann, Merten\|Henklein, Peter\|Biskup, Christoph\|Westermann, Martin\|Hollenberg, Morley D\|Settmacher, Utz
PMID:	17323377

64.
Journal:	J Cell Physiol. 2007 Aug;212(2):526-36.
Title:	MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells.
Author:	Bessard, Anne\|Fremin, Christophe\|Ezan, Frederic\|Coutant, Alexandre\|Baffet, Georges
PMID:	17427199

65.
Journal:	Mol Cells. 2007 Feb 28;23(1):30-8.
Title:	Opposing effects of ERK and p38 MAP kinases on HeLa cell apoptosis induced by dipyrithione.
Author:	Fan, Yumei\|Chen, Hui\|Qiao, Bo\|Luo, Lan\|Ma, Hsiaoyen\|Li, Heng\|Jiang, Jihong\|Niu, Dezhong\|Yin, Zhimin
PMID:	17464209

66.
Journal:	J Hepatol. 2007 Sep;47(3):325-37.
Title:	Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis.
Author:	Chin, Ruth\|Earnest-Silveira, Linda\|Koeberlein, Bernd\|Franz, Susanne\|Zentgraf, Hanswalter\|Dong, Xuebin\|Gowans, Eric\|Bock, C-Thomas\|Torresi, Joseph
PMID:	17512084

67.
Journal:	Cancer Biol Ther. 2007 Jul;6(7):1044-50.
Title:	Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells.
Author:	Xiao, Yu\|Yang, Feng-Qing\|Li, Shao-Ping\|Gao, Jian-Li\|Hu, Guang\|Lao, Sin-Cheng\|Conceicao, Emilia Leong\|Fung, Kwok-Pui\|Wangl, Yi-Tao\|Lee, Simon Ming-Yuen
PMID:	17611410

68.
Journal:	Food Chem Toxicol. 2007 Dec;45(12):2446-53.
Title:	MAPK inhibitors and pifithrin-alpha block cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells.
Author:	Wu, Shu-Jing\|Ng, Lean-Teik
PMID:	17673346

69.
Journal:	Hepatogastroenterology. 2007 Jul-Aug;54(77):1339-44.
Title:	Intestinal trefoil factor (TFF-3) and extracellular signal-regulated kinase (ERK) in cholangiocarcinoma.
Author:	Ailawadhi, Sikander\|Nagase, Hiroki\|Khoury, Thaer\|Yu, Jihnhee\|Tan, Dongfeng\|Black, Jennifer\|Brattain, Michael\|Javle, Milind
PMID:	17708250

70.
Journal:	J Clin Invest. 2007 Sep;117(9):2713-22.
Title:	Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma.
Author:	Calvisi, Diego F\|Ladu, Sara\|Gorden, Alexis\|Farina, Miriam\|Lee, Ju-Seog\|Conner, Elizabeth A\|Schroeder, Insa\|Factor, Valentina M\|Thorgeirsson, Snorri S
PMID:	17717605

71.
Journal:	Hepatology. 2007 Dec;46(6):1801-9.
Title:	Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins.
Author:	Bergamini, Carlo\|Sgarra, Concetta\|Trerotoli, Paolo\|Lupo, Luigi\|Azzariti, Amalia\|Antonaci, Salvatore\|Giannelli, Gianluigi
PMID:	17948258

72.
Journal:	Zhonghua Wai Ke Za Zhi. 2007 Jul 1;45(13):917-20.
Title:	[The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma].
Author:	Zhu, Hong\|Chen, Xiao-Ping\|Luo, Shun-Feng\|Guan, Jian\|Zhang, Wan-Guang\|Zhang, Bi-Xiang\|Mao, Cai-Ping
PMID:	17953842

73.
Journal:	Arch Biochem Biophys. 2007 Dec 1;468(1):100-6.
Title:	Fludarabine reduces survivability of HepG2 cells through VEGF under hypoxia.
Author:	Xue, Jing\|Bi, Xinsheng\|Wu, Guohao\|Meng, Dan\|Fang, Jing
PMID:	17961496

74.
Journal:	Curr Pharm Des. 2007;13(32):3279-87.
Title:	Molecular pathways and related target therapies in liver carcinoma.
Author:	Tommasi, S\|Pinto, R\|Pilato, B\|Paradiso, A
PMID:	18045179

75.
Journal:	Cancer Biol Ther. 2007 Sep;6(9):1461-8. Epub 2007 Jun 26.
Title:	Potentiation of the antitumor effects of both selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatic cancer cells by inhibition of the MEK/ERK pathway.
Author:	Cusimano, Antonella\|Fodera, Daniela\|D'Alessandro, Natale\|Lampiasi, Nadia\|Azzolina, Antonina\|Montalto, Giuseppe\|Cervello, Melchiorre
PMID:	18424914

76.
Journal:	J Surg Res. 2008 Jun 1;147(1):23-33.
Title:	Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway.
Author:	Moran, Dairmuid M\|Mattocks, M Adrian\|Cahill, Paul A\|Koniaris, Leonidas G\|McKillop, Iain H
PMID:	17574577

77.
Journal:	Oncogene. 2008 Jan 3;27(1):85-97.
Title:	Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
Author:	Desnoyers, L R\|Pai, R\|Ferrando, R E\|Hotzel, K\|Le, T\|Ross, J\|Carano, R\|D'Souza, A\|Qing, J\|Mohtashemi, I\|Ashkenazi, A\|French, D M
PMID:	17599042

78.
Journal:	J Cancer Res Clin Oncol. 2008 Apr;134(4):503-13.
Title:	siRNA mediated the type 1 insulin-like growth factor receptor and epidermal growth factor receptor silencing induces chemosensitization of liver cancer cells.
Author:	Niu, Jian\|Li, Xiang-Nong\|Qian, Haixin\|Han, Zeguang
PMID:	17901981

79.
Journal:	Virology. 2008 Feb 5;371(1):61-70.
Title:	NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways.
Author:	Lu, Lili\|Wei, Liang\|Peng, Guiqing\|Mu, Yongxin\|Wu, Kailang\|Kang, Lei\|Yan, Xiaohong\|Zhu, Ying\|Wu, Jianguo
PMID:	17964630

80.
Journal:	Drug Metab Dispos. 2008 Feb;36(2):217-22.
Title:	Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta.
Author:	Le Vee, Marc\|Gripon, Philippe\|Stieger, Bruno\|Fardel, Olivier
PMID:	17991769

81.
Journal:	Chem Biol Interact. 2008 Jan 10;171(1):1-14.
Title:	Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines.
Author:	Sa, Fei\|Gao, Jian-Li\|Fung, Kwok-Pui\|Zheng, Ying\|Lee, Simon Ming-Yuen\|Wang, Yi-Tao
PMID:	17996228

82.
Journal:	J Hepatol. 2008 Jan;48(1):83-90.
Title:	Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection.
Author:	Schmitz, Klaus Juergen\|Wohlschlaeger, Jeremias\|Lang, Hauke\|Sotiropoulos, Georgios Charalambos\|Malago, Massimo\|Steveling, Karen\|Reis, Henning\|Cicinnati, Vito Rosario\|Schmid, Kurt Werner\|Baba, Hideo Andreas
PMID:	17998146

83.
Journal:	J Cell Biochem. 2008 May 1;104(1):176-88.
Title:	Up-regulation of p21CIP1 expression mediated by ERK-dependent and -independent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hepatoma cell proliferation.
Author:	Shirako, Erika\|Hirayama, Naoki\|Tsukada, Yu-ichi\|Tanaka, Toshiaki\|Kitamura, Naomi
PMID:	18004740

84.
Journal:	J Exp Med. 2008 Jan 21;205(1):91-103.
Title:	Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3.
Author:	Riehle, Kimberly J\|Campbell, Jean S\|McMahan, Ryan S\|Johnson, Melissa M\|Beyer, Richard P\|Bammler, Theo K\|Fausto, Nelson
PMID:	18158318

85.
Journal:	Cancer Lett. 2008 Apr 8;262(1):10-8.
Title:	EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells.
Author:	Shimizu, Masahito\|Shirakami, Yohei\|Sakai, Hiroyasu\|Tatebe, Hideharu\|Nakagawa, Takayuki\|Hara, Yukihiko\|Weinstein, I Bernard\|Moriwaki, Hisataka
PMID:	18164805

86.
Journal:	Langenbecks Arch Surg. 2008 May;393(3):333-41.
Title:	Dual inhibition of Raf and VEGFR2 reduces growth and vascularization of hepatocellular carcinoma in an experimental model.
Author:	Lang, Sven Arke\|Brecht, Isabel\|Moser, Christian\|Obed, Aiman\|Batt, David\|Schlitt, Hans Juergen\|Geissler, Edward Kenneth\|Stoeltzing, Oliver
PMID:	18297306

87.
Journal:	Ann Hepatol. 2008 Jan-Mar;7(1):46-51.
Title:	Sorafenib, a systemic therapy for hepatocellular carcinoma.
Author:	Mendez-Sanchez, Nahum\|Vasquez-Fernandez, Francisco\|Zamora-Valdes, Daniel\|Uribe, Misael
PMID:	18376365

88.
Journal:	Clin Cancer Res. 2008 May 1;14(9):2806-12.
Title:	Synergistic growth inhibition by 9-cis-retinoic acid plus trastuzumab in human hepatocellular carcinoma cells.
Author:	Tatebe, Hideharu\|Shimizu, Masahito\|Shirakami, Yohei\|Tsurumi, Hisashi\|Moriwaki, Hisataka
PMID:	18451248

89.
Journal:	J Surg Res. 2008 Dec;150(2):219-26.
Title:	The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC.
Author:	Choi, Jennifer\|Yip-Schneider, Michele\|Albertin, Faith\|Wiesenauer, Chad\|Wang, Yufang\|Schmidt, C Max
PMID:	18468633

90.
Journal:	Antivir Ther. 2008;13(2):221-30.
Title:	Failure of lamivudine to reverse hepatitis B virus-associated changes in ERK, Akt and cell cycle regulatory proteins.
Author:	Chin, Ruth\|Earnest-Silveira, Linda\|Koeberlein, Bernd\|Franz, Susanne\|Zentgraf, Hanswalter\|Bowden, Scott\|Bock, C-Thomas\|Torresi, Joseph
PMID:	18505173

91.
Journal:	Apoptosis. 2008 Sep;13(9):1135-47.
Title:	Downregulation of hepatoma-derived growth factor activates the Bad-mediated apoptotic pathway in human cancer cells.
Author:	Tsang, Tsun Yee\|Tang, Wan Yee\|Tsang, Wing Pui\|Co, Ngai Na\|Kong, Siu Kai\|Kwok, Tim Tak
PMID:	18651222

92.
Journal:	BMC Cancer. 2008 Jul 23;8:206.
Title:	ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo.
Author:	Moser, Christian\|Lang, Sven A\|Mori, Akira\|Hellerbrand, Claus\|Schlitt, Hans J\|Geissler, Edward K\|Fogler, William E\|Stoeltzing, Oliver
PMID:	18651980

93.
Journal:	Int J Cancer. 2008 Nov 1;123(9):2057-64.
Title:	Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.
Author:	Calvisi, Diego F\|Pinna, Federico\|Pellegrino, Rossella\|Sanna, Valeria\|Sini, Marcella\|Daino, Lucia\|Simile, Maria M\|De Miglio, Maria R\|Frau, Maddalena\|Tomasi, Maria L\|Seddaiu, Maria A\|Muroni, Maria R\|Feo, Francesco\|Pascale, Rosa M
PMID:	18697198

94.
Journal:	Aliment Pharmacol Ther. 2008 Dec 1;28(11-12):1269-77.
Title:	Review article: pharmacological therapy for hepatocellular carcinoma with sorafenib and other oral agents.
Author:	Chaparro, M\|Gonzalez Moreno, L\|Trapero-Marugan, M\|Medina, J\|Moreno-Otero, R
PMID:	18808443

95.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(9):1684-7.
Title:	[Coadministration of sorafenib and cisplatin inhibits proliferation of hepatocellular carcinoma HepG2 cells in vitro].
Author:	Chen, Feng-sheng\|Cui, Yan-zhi\|Luo, Rong-cheng\|Wu, Jing\|Zhang, Hua
PMID:	18819900

96.
Journal:	Tumori. 2008 Jul-Aug;94(4):523-30.
Title:	Cellular mechanisms of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MAPK signaling in hepatocellular carcinoma.
Author:	Lee, Kyung Hee\|Choi, Eun Young\|Hyun, Myung Soo\|Eun, Jong Ryul\|Jang, Byung Ik\|Kim, Tae Nyeun\|Lee, Heon Ju\|Lee, Dong Shik\|Yun, Sung Su\|Kim, Hong Jin\|Kim, Jung Hye\|Kim, Jae-Ryong
PMID:	18822689

97.
Journal:	Cancer Invest. 2008 Dec;26(10):977-83.
Title:	Expression of CD147 mediates tumor cells invasion and multidrug resistance in hepatocellular carcinoma.
Author:	Jia, Li\|Xu, Henggui\|Zhao, Yongfu\|Jiang, Lili\|Yu, Jingda\|Zhang, Jianing
PMID:	19093255

98.
Journal:	J Biol Chem. 2009 Jan 2;284(1):495-504.
Title:	Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survival.
Author:	Haimerl, Florian\|Erhardt, Annette\|Sass, Gabriele\|Tiegs, Gisa
PMID:	19001362

99.
Journal:	Mol Carcinog. 2009 Jun;48(6):553-62.
Title:	Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis.
Author:	Huang, Xinqiang\|Yang, Chaofeng\|Jin, Chengliu\|Luo, Yongde\|Wang, Fen\|McKeehan, Wallace L
PMID:	19009564

100.
Journal:	Int J Mol Med. 2009 Feb;23(2):189-96.
Title:	Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line.
Author:	Auyeung, Kathy Ka-wai\|Law, Pui-ching\|Ko, Joshua Ka-shun
PMID:	19148542

101.
Journal:	J Cell Mol Med. 2009 Aug;13(8B):2673-83.
Title:	Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Author:	Huynh, Hung\|Ngo, Van Chanh\|Koong, Heng Nung\|Poon, Donald\|Choo, Su Pin\|Thng, Choon Hua\|Chow, Pierce\|Ong, Hock Soo\|Chung, Alexander\|Soo, Khee Chee
PMID:	19220580

102.
Journal:	J Pharmacol Exp Ther. 2009 Jun;329(3):1063-70.
Title:	Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
Author:	Yip-Schneider, Michele T\|Klein, Patrick J\|Wentz, Sabrina C\|Zeni, Amer\|Menze, Alex\|Schmidt, C Max
PMID:	19258520

103.
Journal:	Exp Mol Med. 2009 Mar 31;41(3):180-8.
Title:	Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor.
Author:	Lee, Kyung Hee\|Kim, Jae Ryong
PMID:	19293637

104.
Journal:	J Hepatol. 2009 Jun;50(6):1112-21.
Title:	Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo.
Author:	Lai, Jin-Ping\|Sandhu, Dalbir S\|Moser, Catherine D\|Cazanave, Sophie C\|Oseini, Abdul M\|Shire, Abdirashid M\|Shridhar, Viji\|Sanderson, Schuyler O\|Roberts, Lewis R
PMID:	19376607

105.
Journal:	World J Gastroenterol. 2009 Apr 28;15(16):1943-50.
Title:	Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice.
Author:	Cui, Wei\|Gu, Fan\|Hu, Ke-Qin
PMID:	19399925

106.
Journal:	Nat Prod Res. 2009;23(8):704-18.
Title:	Inhibitory effect of immature plum on PMA-induced MMP-9 expression in human hepatocellular carcinoma.
Author:	Yu, Mi Hee\|Gwon Im, Hyo\|Gyu Lee, Sung\|Kim, Dae-Ik\|Jeong Seo, Hwa\|Lee, In-Seon
PMID:	19418353

107.
Journal:	Int J Oncol. 2009 Jun;34(6):1749-57.
Title:	Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells.
Author:	Dai, Rongyang\|Chen, Run\|Li, Hong
PMID:	19424594

108.
Journal:	Exp Biol Med (Maywood). 2009 Jul;234(7):726-36.
Title:	Genetic and epigenetic control of molecular alterations in hepatocellular carcinoma.
Author:	Feo, Francesco\|Frau, Maddalena\|Tomasi, Maria L\|Brozzetti, Stefania\|Pascale, Rosa M
PMID:	19429855

109.
Journal:	J Exp Clin Cancer Res. 2009 May 18;28:65.
Title:	Expression of phospho-ERK1/2 and PI3-K in benign and malignant gallbladder lesions and its clinical and pathological correlations.
Author:	Li, Qinglong\|Yang, Zhulin
PMID:	19445727

110.
Journal:	IUBMB Life. 2009 Jun;61(6):685-92.
Title:	Tax1 enhances cancer cell proliferation via Ras-Raf-MEK-ERK signaling pathway.
Author:	Song, Chunjiao\|Wang, Weimin\|Li, Meng\|Liu, Yanxin\|Zheng, Dexian
PMID:	19472191

111.
Journal:	J Proteome Res. 2009 Aug;8(8):3987-94.
Title:	Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors.
Author:	Rignall, Benjamin\|Ittrich, Carina\|Krause, Eberhard\|Appel, Klaus E\|Buchmann, Albrecht\|Schwarz, Michael
PMID:	19476384

112.
Journal:	Cancer Lett. 2009 Nov 28;285(2):210-7.
Title:	Acyclic retinoid synergises with valproic acid to inhibit growth in human hepatocellular carcinoma cells.
Author:	Tatebe, Hideharu\|Shimizu, Masahito\|Shirakami, Yohei\|Sakai, Hiroyasu\|Yasuda, Yoichi\|Tsurumi, Hisashi\|Moriwaki, Hisataka
PMID:	19520494

113.
Journal:	Cancer Sci. 2009 Oct;100(10):1957-62.
Title:	(-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis.
Author:	Shirakami, Yohei\|Shimizu, Masahito\|Adachi, Seiji\|Sakai, Hiroyasu\|Nakagawa, Takayuki\|Yasuda, Yoichi\|Tsurumi, Hisashi\|Hara, Yukihiko\|Moriwaki, Hisataka
PMID:	19558547

114.
Journal:	Oncol Rep. 2009 Sep;22(3):599-604.
Title:	Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue.
Author:	Ide, Yasushi\|Zhang, Hao\|Hamajima, Hiroshi\|Kawaguchi, Yasunori\|Eguchi, Yuichiro\|Mizuta, Toshihiko\|Yamamoto, Kyosuke\|Fujimoto, Kazuma\|Ozaki, Iwata
PMID:	19639210

115.
Journal:	BMC Med. 2009 Aug 24;7:41.
Title:	Phosphorylated ERK is a potential predictor of sensitivity to sorafenib when treating hepatocellular carcinoma: evidence from an in vitro study.
Author:	Zhang, Zhe\|Zhou, Xiaoyun\|Shen, Hujia\|Wang, Dexing\|Wang, Yanhong
PMID:	19698189

116.
Journal:	Biomed Environ Sci. 2009 Jun;22(3):244-52.
Title:	Role of prosurvival molecules in the action of lidamycin toward human tumor cells.
Author:	Yang, A-Jing\|Shi, Wei-Wei\|Li, Yong\|Wang, Zhen\|Shao, Rong-Guang\|Li, Dian-Dong\|He, Qi-Yang
PMID:	19725468

117.
Journal:	Am J Chin Med. 2009;37(5):923-31.
Title:	Rhein lysinate suppresses the growth of tumor cells and increases the anti-tumor activity of Taxol in mice.
Author:	Lin, Ya-Jun\|Zhen, Yong-Zhan\|Shang, Bo-Yang\|Zhen, Yong-Su
PMID:	19885952

118.
Journal:	Cancer Chemother Pharmacol. 2010 Apr;65(5):903-11.
Title:	Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line.
Author:	Roy, Karnati R\|Reddy, Gorla V\|Maitreyi, Leela\|Agarwal, Smita\|Achari, Chandrani\|Vali, Shireen\|Reddanna, Pallu
PMID:	19685055

119.
Journal:	Virus Res. 2010 Jan;147(1):7-16.
Title:	Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus.
Author:	Chin, Ruth\|Nachbur, Ulrich\|Earnest-Silveira, Linda\|Bankovacki, Aleksandra\|Koeberlein, Bernd\|Zentgraf, Hanswalter\|Bock, C-Thomas\|Silke, John\|Torresi, Joseph
PMID:	19786052

120.
Journal:	J Hepatol. 2010 Jan;52(1):79-87.
Title:	AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC).
Author:	Huynh, Hung\|Ngo, Van Chanh\|Koong, Heng Nung\|Poon, Donald\|Choo, Su Pin\|Toh, Han Chong\|Thng, Choon Hua\|Chow, Pierce\|Ong, Hock Soo\|Chung, Alexander\|Goh, Boon Cher\|Smith, Paul D\|Soo, Khee Chee
PMID:	19910069

121.
Journal:	Liver Int. 2010 Jan;30(1):31-41.
Title:	Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells.
Author:	Sancho-Bru, Pau\|Juez, Elena\|Moreno, Montserrat\|Khurdayan, Valeria\|Morales-Ruiz, Manuel\|Colmenero, Jordi\|Arroyo, Vicente\|Brenner, David A\|Gines, Pere\|Bataller, Ramon
PMID:	19929904

122.
Journal:	Expert Opin Investig Drugs. 2010 Feb;19(2):265-74.
Title:	Targeted therapy of hepatocellular cancer.
Author:	Wysocki, Piotr Jan
PMID:	20074016

123.
Journal:	Cancer. 2010 Mar 1;116(5):1315-25.
Title:	AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma.
Author:	Huynh, Hung
PMID:	20101735

124.
Journal:	Virol J. 2010 Feb 20;7:45.
Title:	Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2.
Author:	Li, Weihua\|Miao, Xiaohui\|Qi, Zhongtian\|Zeng, Wenting\|Liang, Jianxin\|Liang, Zengwei
PMID:	20170530

125.
Journal:	Mol Aspects Med. 2010 Apr;31(2):179-93.
Title:	Prognostic markers and putative therapeutic targets for hepatocellular carcinoma.
Author:	Frau, Maddalena\|Biasi, Fiorella\|Feo, Francesco\|Pascale, Rosa M
PMID:	20176048

126.
Journal:	Am J Transl Res. 2010 Jan 23;2(1):105-18.
Title:	Molecular genetics of hepatocellular neoplasia.
Author:	Jain, Shilpa\|Singhal, Shashideep\|Lee, Peng\|Xu, Ruliang
PMID:	20182587

127.
Journal:	Eur J Gastroenterol Hepatol. 2010 Sep;22(9):1106-10.
Title:	Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib.
Author:	Ozenne, Violaine\|Paradis, Valerie\|Pernot, Simon\|Castelnau, Corinne\|Vullierme, Marie-Pierre\|Bouattour, Mohamed\|Valla, Dominique\|Farges, Olivier\|Degos, Francoise
PMID:	20300004

128.
Journal:	Cancer Sci. 2010 Jun;101(6):1501-10.
Title:	Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma.
Author:	Deng, Ying-Bing\|Nagae, Genta\|Midorikawa, Yutaka\|Yagi, Koichi\|Tsutsumi, Shuichi\|Yamamoto, Shogo\|Hasegawa, Kiyoshi\|Kokudo, Norihiro\|Aburatani, Hiroyuki\|Kaneda, Atsushi
PMID:	20345479

129.
Journal:	J Agric Food Chem. 2010 May 12;58(9):5806-14.
Title:	Polyphenol-rich extracts from Solanum nigrum attenuated PKC alpha-mediated migration and invasion of hepatocellular carcinoma cells.
Author:	Yang, Mon-Yuan\|Hsu, Li-Sung\|Peng, Chiung-Huei\|Shi, Yuan-Shong\|Wu, Cheng-Hsun\|Wang, Chau-Jong
PMID:	20349911

130.
Journal:	Biochem Pharmacol. 2010 Sep 1;80(5):550-60.
Title:	Molecularly targeted therapy in hepatocellular carcinoma.
Author:	Huynh, Hung
PMID:	20371362

131.
Journal:	J Biol Inorg Chem. 2010 Sep;15(7):1087-97.
Title:	Vanadium compounds discriminate hepatoma and normal hepatic cells by differential regulation of reactive oxygen species.
Author:	Wang, Qin\|Liu, Tong-Tong\|Fu, Ying\|Wang, Kui\|Yang, Xiao-Gai
PMID:	20443032

132.
Journal:	J Biomed Sci. 2010 May 6;17:35.
Title:	PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells.
Author:	Chiang, Chao-Wei\|Huang, Yi\|Leong, Ka-Wai\|Chen, Lih-Chyang\|Chen, Hua-Chien\|Chen, Shu-Jen\|Chou, Chen-Kung
PMID:	20444294

133.
Journal:	Mol Cancer. 2010 Jun 12;9:146.
Title:	Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old.
Author:	Colak, Dilek\|Chishti, Muhammad A\|Al-Bakheet, Al-Bandary\|Al-Qahtani, Ahmed\|Shoukri, Mohamed M\|Goyns, Malcolm H\|Ozand, Pinar T\|Quackenbush, John\|Park, Ben H\|Kaya, Namik
PMID:	20540791

134.
Journal:	Biol Chem. 2010 Jul;391(7):791-801.
Title:	miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27(Kip1)- and MEK/ERK-mediated cell cycle regulation.
Author:	Dai, Rongyang\|Li, Juan\|Liu, Youping\|Yan, Dongmei\|Chen, Shaokun\|Duan, Chunyan\|Liu, Xiaoyan\|He, Tao\|Li, Hong
PMID:	20624000

135.
Journal:	Biochemistry. 2010 Sep 14;49(36):7811-20.
Title:	3'-Sulfo-Le(x) is important for regulation of integrin subunit alphaV.
Author:	Zhang, Chun-Yi\|Hu, Ping\|Fu, Da\|Wu, Wei\|Jia, Cheng-You\|Zhu, Xu Chao\|Wu, Xing Zhong
PMID:	20695481

136.
Journal:	J Hepatol. 2010 Nov;53(5):872-9.
Title:	PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection.
Author:	Xu, Yong-Feng\|Yi, Yong\|Qiu, Shuang-Jian\|Gao, Qiang\|Li, Yi-Wei\|Dai, Chen-Xin\|Cai, Ming-Yan\|Ju, Min-Jie\|Zhou, Jian\|Zhang, Bo-Heng\|Fan, Jia
PMID:	20739083

137.
Journal:	Neurosci Lett. 2010 Nov 5;484(3):210-4.
Title:	Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells.
Author:	Dong, Lin\|Qi, Nan\|Ge, Rui-Min\|Cao, Cui-Li\|Lan, Feng\|Shen, Li
PMID:	20800650

138.
Journal:	Cytotechnology. 2010 Oct;62(5):449-60.
Title:	Perifosine induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cell lines by blockade of Akt phosphorylation.
Author:	Fei, Hong-Rong\|Chen, Geng\|Wang, Jian-Mei\|Wang, Feng-Ze
PMID:	20842425

139.
Journal:	Eur J Pharmacol. 2010 Dec 15;649(1-3):74-83.
Title:	C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line.
Author:	Nishanth, Reddy P\|Ramakrishna, B S\|Jyotsna, Radhika G\|Roy, Karnati R\|Reddy, Gorla V\|Reddy, Pratap K\|Reddanna, Pallu
PMID:	20858479

140.
Journal:	Cell Mol Biol (Noisy-le-grand). 2010 Sep 11;56 Suppl:OL1366-72.
Title:	Cisplatin induces programmed death-1-ligand 1(PD-L1) over-expression in hepatoma H22 cells via Erk /MAPK signaling pathway.
Author:	Qin, X\|Liu, C\|Zhou, Y\|Wang, G
PMID:	20937224

141.
Journal:	Anticancer Res. 2010 Dec;30(12):4951-8.
Title:	PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways.
Author:	Gedaly, Roberto\|Angulo, Paul\|Hundley, Jonathan\|Daily, Michael F\|Chen, Changguo\|Koch, Alvaro\|Evers, B Mark
PMID:	21187475

142.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2010 Dec;18(12):909-14.
Title:	[Cross-talk between PI3K/Akt and MEK/ERK pathways regulates human hepatocellular carcinoma cell cycle progression under endoplasmic reticulum stress].
Author:	Yan, Dong-mei\|Dai, Rong-yang\|Duan, Chun-yan\|Chen, Shao-kun\|Liu, You-ping\|Chen, Chuan-ning\|Li, Hong
PMID:	21205476

143.
Journal:	Oncol Res. 2010;19(2):67-76.
Title:	Hepatoma-derived growth factor regulates the bad-mediated apoptotic pathway and induction of vascular endothelial growth factor in stomach cancer cells.
Author:	Lee, Kyung Hee\|Choi, Eun Young\|Kim, Min Kyoung\|Lee, Si Hyung\|Jang, Byung Ik\|Kim, Tae Nyeun\|Kim, Se Won\|Kim, Sang Woon\|Song, Sun Kyo\|Kim, Jae-Ryong\|Jung, Bo Chan
PMID:	21302807

144.
Journal:	Exp Toxicol Pathol. 2011 Jan;63(1-2):167-73.
Title:	Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells.
Author:	Parekh, Palak\|Motiwale, Leena\|Naik, Nishigandha\|Rao, K V K
PMID:	20133117

145.
Journal:	Cancer Gene Ther. 2011 Jan;18(1):20-5.
Title:	Effects of siRNA-targeting BMP-2 on the abilities of migration and invasion of human liver cancer SMMC7721 cells and its mechanism.
Author:	Wu, J-B\|Fu, H-Q\|Huang, L-Z\|Liu, A-W\|Zhang, J-X
PMID:	20885449

146.
Journal:	Semin Cancer Biol. 2011 Feb;21(1):10-20.
Title:	Mitogen-activated protein kinases in hepatocellular carcinoma development.
Author:	Min, Lihua\|He, Baokun\|Hui, Lijian
PMID:	20969960

147.
Journal:	Cancer Prev Res (Phila). 2011 Jan;4(1):128-36.
Title:	Acyclic retinoid inhibits diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BLKS/J- +(db)/+Lepr(db) mice.
Author:	Shimizu, Masahito\|Sakai, Hiroyasu\|Shirakami, Yohei\|Iwasa, Junpei\|Yasuda, Yoichi\|Kubota, Masaya\|Takai, Koji\|Tsurumi, Hisashi\|Tanaka, Takuji\|Moriwaki, Hisataka
PMID:	21071580

148.
Journal:	Int J Cancer. 2011 Sep 15;129(6):1519-31.
Title:	Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma.
Author:	Liu, Chaoyang\|Gong, Ke\|Mao, Xin\|Li, Wenhua
PMID:	21128229

149.
Journal:	J Hepatol. 2011 May;54(5):939-47.
Title:	Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis.
Author:	Um, Tae-Hee\|Kim, Haeryoung\|Oh, Bong-Kyeong\|Kim, Myoung Soo\|Kim, Kyung Sik\|Jung, Guhung\|Park, Young Nyun
PMID:	21145824

150.
Journal:	J Biol Chem. 2011 Feb 18;286(7):5913-20.
Title:	Growth suppression of human hepatocellular carcinoma xenografts by a monoclonal antibody CH12 directed to epidermal growth factor receptor variant III.
Author:	Jiang, Hua\|Wang, Huamao\|Tan, Zhonghua\|Hu, Suwen\|Wang, Hai\|Shi, Bizhi\|Yang, Lin\|Li, Peiyong\|Gu, Jianren\|Wang, Hongyang\|Li, Zonghai
PMID:	21163950

151.
Journal:	Cancer Biol Ther. 2011 Mar 1;11(5):524-34. Epub 2011 Mar 1.
Title:	Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.
Author:	Beljanski, Vladimir\|Lewis, Clayton S\|Smith, Charles D
PMID:	21258214

152.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2011 Jan;19(1):48-51.
Title:	[Relative analysis of OPN and its related signal molecules in hepatocellular carcinoma].
Author:	Zhang, Lan\|Li, Hai-yu\|Yin, Xiao-lu\|Xu, Yan-ping\|Chen, Yi\|Xie, Xiao-ying\|Shen, Yue-fang\|Ye, Qing-hai\|Ren, Zheng-gang
PMID:	21272459

153.
Journal:	Hepatology. 2011 Feb;53(2):577-86.
Title:	Effect of sorafenib on murine liver regeneration.
Author:	Hora, Caroline\|Romanque, Pamela\|Dufour, Jean-Francois F
PMID:	21274878

154.
Journal:	Biochem Pharmacol. 2011 Apr 1;81(7):917-24.
Title:	The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-beta-induced apoptosis of liver tumor cells.
Author:	Sancho, Patricia\|Fabregat, Isabel
PMID:	21276422

155.
Journal:	Cancer Prev Res (Phila). 2011 Mar;4(3):396-403.
Title:	Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.
Author:	Shimizu, Masahito\|Sakai, Hiroyasu\|Shirakami, Yohei\|Yasuda, Yoichi\|Kubota, Masaya\|Terakura, Daishi\|Baba, Atsushi\|Ohno, Tomohiko\|Hara, Yukihiko\|Tanaka, Takuji\|Moriwaki, Hisataka
PMID:	21372039

156.
Journal:	Hepatology. 2011 Jun;53(6):1932-42.
Title:	RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathway.
Author:	Wang, Suihai\|Huang, Xiang\|Li, Yue\|Lao, Haimiao\|Zhang, Ying\|Dong, Huimin\|Xu, Weiwen\|Li, Ji-Liang\|Li, Ming
PMID:	21391225

157.
Journal:	Clin Sci (Lond). 2011 Aug;121(4):159-68.
Title:	Hepatic stellate cells stimulate HCC cell migration via laminin-5 production.
Author:	Santamato, Angela\|Fransvea, Emilia\|Dituri, Francesco\|Caligiuri, Alessandra\|Quaranta, Michele\|Niimi, Tomoaki\|Pinzani, Massimo\|Antonaci, Salvatore\|Giannelli, Gianluigi
PMID:	21413933

158.
Journal:	Apoptosis. 2011 Jul;16(7):683-95.
Title:	Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment.
Author:	Zhang, Chris Z Y\|Zhang, H T\|Chen, George G\|Lai, Paul B S
PMID:	21468663

159.
Journal:	BMC Cancer. 2011 Apr 22;11:150.
Title:	Isomalto oligosaccharide sulfate inhibits tumor growth and metastasis of hepatocellular carcinoma in nude mice.
Author:	Xiao, Chun-Li\|Tao, Zhong-Hua\|Guo, Lin\|Li, Wei-Wei\|Wan, Jin-Liang\|Sun, Hui-Chuan\|Wang, Lu\|Tang, Zhao-You\|Fan, Jia\|Wu, Wei-Zhong
PMID:	21513518

160.
Journal:	Mol Med Rep. 2011 Jul-Aug;4(4):719-22.
Title:	Blockade of IGF-IR exerts anticancer effects in hepatocellular carcinoma.
Author:	Yao, Wei-Feng\|Liu, Jun-Wei\|Sheng, Guo-Liang\|Huang, Dong-Sheng
PMID:	21567089

161.
Journal:	Biochem Biophys Res Commun. 2011 Jun 17;409(4):752-7.
Title:	ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways.
Author:	Yang, Lifang\|Ling, Yong\|Zhang, Zhenzhen\|Zhao, Qian\|Tang, Jianxin\|Ji, Hui\|Zhang, Yihua
PMID:	21621522

162.
Journal:	Yakugaku Zasshi. 2011;131(6):993-1000.
Title:	Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
Author:	Wang, Ze-Jian\|Song, Li\|Guo, Lin-Chen\|Yin, Min\|Sun, Yong Ning
PMID:	21628989

163.
Journal:	J Agric Food Chem. 2011 Jul 13;59(13):7104-13.
Title:	Hispolon induces apoptosis and cell cycle arrest of human hepatocellular carcinoma Hep3B cells by modulating ERK phosphorylation.
Author:	Huang, Guan-Jhong\|Deng, Jeng-Shyan\|Huang, Shyh-Shyun\|Hu, Miao-Lin
PMID:	21630638

164.
Journal:	J Gen Virol. 2011 Oct;92(Pt 10):2237-48.
Title:	Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly.
Author:	Pei, Rongjuan\|Chen, Honghe\|Lu, Lu\|Zhu, Wandi\|Beckebaum, Susanne\|Cicinnati, Vito\|Lu, Mengji\|Chen, Xinwen
PMID:	21653755

165.
Journal:	Cancer Gene Ther. 2011 Jul;18(7):520-30.
Title:	DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma.
Author:	Singhal, G\|Akhter, M Z\|Stern, D F\|Gupta, S D\|Ahuja, A\|Sharma, U\|Jagannathan, N R\|Rajeswari, M R
PMID:	21660063

166.
Journal:	Biochem Biophys Res Commun. 2011 Jul 15;410(4):803-8.
Title:	Regulation of human hepatocellular carcinoma cells by Spred2 and correlative studies on its mechanism.
Author:	Ma, Xiao-Ni\|Liu, Xiao-Yun\|Yang, Yue-Feng\|Xiao, Feng-Jun\|Li, Qing-Fang\|Yan, Jun\|Zhang, Qun-Wei\|Wang, Li-Sheng\|Li, Xue-Yan\|Wang, Hua
PMID:	21703232

167.
Journal:	J Pineal Res. 2011 Nov;51(4):463-71.
Title:	Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor.
Author:	Carbajo-Pescador, Sara\|Garcia-Palomo, Andres\|Martin-Renedo, Javier\|Piva, Maiara\|Gonzalez-Gallego, Javier\|Mauriz, Jose L
PMID:	21718361

168.
Journal:	Dis Model Mech. 2011 Nov;4(6):801-13.
Title:	A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish.
Author:	Nguyen, Anh Tuan\|Emelyanov, Alexander\|Koh, Chor Hui Vivien\|Spitsbergen, Jan M\|Lam, Siew Hong\|Mathavan, Sinnakaruppan\|Parinov, Serguei\|Gong, Zhiyuan
PMID:	21729876

169.
Journal:	J Cell Biochem. 2011 Nov;112(11):3430-9.
Title:	Suppression by heat shock protein 20 of hepatocellular carcinoma cell proliferation via inhibition of the mitogen-activated protein kinases and AKT pathways.
Author:	Matsushima-Nishiwaki, Rie\|Adachi, Seiji\|Yoshioka, Takashi\|Yasuda, Eisuke\|Yamagishi, Yasumasa\|Matsuura, Junya\|Muko, Masato\|Iwamura, Rutsu\|Noda, Takahiro\|Toyoda, Hidenori\|Kaneoka, Yuji\|Okano, Yukio\|Kumada, Takashi\|Kozawa, Osamu
PMID:	21769911

170.
Journal:	J Agric Food Chem. 2011 Aug 24;59(16):9032-8.
Title:	Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, p38, and uPA signaling multiple pathways.
Author:	Ma, Chia-Yu\|Ji, Wei-Ting\|Chueh, Fu-Shin\|Yang, Jai-Sing\|Chen, Po-Yuan\|Yu, Chien-Chih\|Chung, Jing-Gung
PMID:	21770460

171.
Journal:	Alcohol Clin Exp Res. 2011 Dec;35(12):2216-25.
Title:	Alcohol induces liver neoplasia in a novel alcohol-preferring rat model.
Author:	Yip-Schneider, Michele T\|Doyle, Courtney J\|McKillop, Iain H\|Wentz, Sabrina C\|Brandon-Warner, Elizabeth\|Matos, Jesus M\|Sandrasegaran, Kumaresan\|Saxena, Romil\|Hennig, Matthew E\|Wu, Huangbing\|Waters, Joshua A\|Klein, Patrick J\|Froehlich, Janice C\|Schmidt, C M
PMID:	21790668

172.
Journal:	Med Chem. 2011 Sep;7(5):432-42.
Title:	Chebulagic acid synergizes the cytotoxicity of doxorubicin in human hepatocellular carcinoma through COX-2 dependant modulation of MDR-1.
Author:	Achari, Chandrani\|Reddy, Gorla V\|Reddy, T C M\|Reddanna, Pallu
PMID:	21801152

173.
Journal:	Exp Mol Pathol. 2011 Dec;91(3):653-9.
Title:	The role of innate immunity in the pathogenesis of preneoplasia in drug-induced chronic hepatitis based on a mouse model.
Author:	French, S W\|Bardag-Gorce, F\|French, B A\|Li, J\|Oliva, J
PMID:	21820428

174.
Journal:	PLoS One. 2011;6(8):e21980.
Title:	Survivin inhibition is critical for Bcl-2 inhibitor-induced apoptosis in hepatocellular carcinoma cells.
Author:	Zhao, Xiangxuan\|Ogunwobi, Olorunseun O\|Liu, Chen
PMID:	21829603

175.
Journal:	Clin Exp Metastasis. 2011 Dec;28(8):851-63.
Title:	Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2.
Author:	Hu, Chi-Tan\|Wu, Jia-Ru\|Cheng, Chuan-Chu\|Wang, Sindy\|Wang, Hsiao-Ting\|Lee, Ming-Che\|Wang, Ling-Jung\|Pan, Siou-Mei\|Chang, Tsu-Yao\|Wu, Wen-Sheng
PMID:	21842414

176.
Journal:	Zhonghua Zhong Liu Za Zhi. 2011 May;33(5):358-62.
Title:	[Expression of Raf kinase inhibitor protein and its significance in invasion and metastasis of hepatocellular carcinoma].
Author:	Wu, Xiao-hui\|Wang, Shun-xiang\|Yang, Yong-jiang\|Li, Jian-kun\|Xu, Zhuo\|Tang, Rui-feng
PMID:	21875465

177.
Journal:	Immunol Lett. 2011 Dec 30;141(1):74-82.
Title:	Effective inhibition of a Strongylocentrotus nudus eggs polysaccharide against hepatocellular carcinoma is mediated via immunoregulation in vivo.
Author:	Wang, Mengyu\|Wang, Hui\|Tang, Ying\|Kang, Di\|Gao, Yu\|Ke, Mengyun\|Dou, Jie\|Xi, Tao\|Zhou, Changlin
PMID:	21893096

178.
Journal:	J Immunol. 2011 Nov 1;187(9):4844-60.
Title:	Hepatitis B virus induces a novel inflammation network involving three inflammatory factors, IL-29, IL-8, and cyclooxygenase-2.
Author:	Yu, Yi\|Gong, Rui\|Mu, Yongxin\|Chen, Yanni\|Zhu, Chengliang\|Sun, Zhichen\|Chen, Mingzhou\|Liu, Yingle\|Zhu, Ying\|Wu, Jianguo
PMID:	21957142

179.
Journal:	For Immunopathol Dis Therap. 2011;2(2):195-204.
Title:	Role of Raf Kinase Inhibitor Protein in Hepatocellular Carcinoma.
Author:	Walker, Evan J\|Rosenberg, Stephen A\|Wands, Jack R\|Kim, Miran
PMID:	21984963

180.
Journal:	Cancer Cell Int. 2011 Nov 17;11:40.
Title:	Involvement of the epidermal growth factor receptor in the modulation of multidrug resistance in human hepatocellular carcinoma cells in vitro.
Author:	Hoffmann, Katrin\|Xiao, Zhi\|Franz, Clemens\|Mohr, Elvira\|Serba, Susanne\|Buchler, Markus W\|Schemmer, Peter
PMID:	22088142

181.
Journal:	Anticancer Res. 2011 Nov;31(11):3883-90.
Title:	Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Author:	Hoffmann, Katrin\|Shibo, Lin\|Xiao, Zhi\|Longerich, Thomas\|Buchler, Markus W\|Schemmer, Peter
PMID:	22110214

182.
Journal:	J Korean Med Sci. 2011 Dec;26(12):1563-8.
Title:	Novel EGFR-TK inhibitor EKB-569 inhibits hepatocellular carcinoma cell proliferation by AKT and MAPK pathways.
Author:	Kim, Heesue\|Lim, Ho Yeong
PMID:	22147992

183.
Journal:	PLoS One. 2011;6(12):e28977.
Title:	Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells.
Author:	Hung, Jui-Hsiang\|Teng, Yen-Ni\|Wang, Lily Hui-Ching\|Su, Ih-Jen\|Wang, Clay C C\|Huang, Wenya\|Lee, Kuan-Han\|Lu, Kuan-Ying\|Wang, Lyu-Han
PMID:	22216150

184.
Journal:	J Cell Mol Med. 2012 Mar;16(3):496-506.
Title:	Regulatory mechanisms of interleukin-8 production induced by tumour necrosis factor-alpha in human hepatocellular carcinoma cells.
Author:	Wang, Yaohui\|Wang, Weimin\|Wang, Lingyan\|Wang, Xiangdong\|Xia, Jinglin
PMID:	21545687

185.
Journal:	Mol Biol Rep. 2012 Feb;39(2):1683-9.
Title:	Bufalin enhances the anti-proliferative effect of sorafenib on human hepatocellular carcinoma cells through downregulation of ERK.
Author:	Gao, Yang\|Li, Hua-Xing\|Xu, Li-Tao\|Wang, Peng\|Xu, Li-Yan\|Cohen, Lorenzo\|Yang, Pei-Ying\|Gu, Ke\|Meng, Zhi-Qiang
PMID:	21617941

186.
Journal:	J Hepatol. 2012 Feb;56(2):419-25.
Title:	Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish.
Author:	Li, Zhen\|Huang, Xiaoqian\|Zhan, Huiqing\|Zeng, Zhiqiang\|Li, Caixia\|Spitsbergen, Jan M\|Meierjohann, Svenja\|Schartl, Manfred\|Gong, Zhiyuan
PMID:	21888874

187.
Journal:	Dis Model Mech. 2012 Jan;5(1):63-72.
Title:	An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.
Author:	Nguyen, Anh Tuan\|Emelyanov, Alexander\|Koh, Chor Hui Vivien\|Spitsbergen, Jan M\|Parinov, Serguei\|Gong, Zhiyuan
PMID:	21903676

188.
Journal:	Exp Mol Pathol. 2012 Feb;92(1):74-81.
Title:	BMP activated Smad signaling strongly promotes migration and invasion of hepatocellular carcinoma cells.
Author:	Maegdefrau, Ulrike\|Bosserhoff, Anja-Katrin
PMID:	22024355

189.
Journal:	J Surg Res. 2012 Aug;176(2):542-8.
Title:	PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.
Author:	Gedaly, Roberto\|Angulo, Paul\|Hundley, Jonathan\|Daily, Michael F\|Chen, Changguo\|Evers, B Mark
PMID:	22261591

190.
Journal:	Eur J Pharmacol. 2012 Mar 15;679(1-3):24-33.
Title:	Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells.
Author:	Yoon, Ji-Hae\|Choi, Yeo-Jin\|Lee, Seong-Gene
PMID:	22314224

191.
Journal:	Int J Mol Med. 2012 May;29(5):855-63.
Title:	Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression.
Author:	Yan, Meng-Yi\|Chien, Su-Yu\|Kuo, Shou-Jen\|Chen, Dar-Ren\|Su, Chin-Cheng
PMID:	22322382

192.
Journal:	Phytomedicine. 2012 May 15;19(7):603-8.
Title:	Ardipusilloside inhibits survival, invasion and metastasis of human hepatocellular carcinoma cells.
Author:	Lou, Lianqing\|Ye, Weiwei\|Chen, Yongxin\|Wu, Shuang\|Jin, Linzheng\|He, Jinke\|Tao, Xingfei\|Zhu, Jinghong\|Chen, Xiangyi\|Deng, Anmei\|Wang, Jinhe
PMID:	22349030

193.
Journal:	J Hepatol. 2012 Jul;57(1):77-83.
Title:	Diacylglycerol kinase alpha enhances hepatocellular carcinoma progression by activation of Ras-Raf-MEK-ERK pathway.
Author:	Takeishi, Kazuki\|Taketomi, Akinobu\|Shirabe, Ken\|Toshima, Takeo\|Motomura, Takashi\|Ikegami, Toru\|Yoshizumi, Tomoharu\|Sakane, Fumio\|Maehara, Yoshihiko
PMID:	22425622

194.
Journal:	PLoS One. 2012;7(3):e33379.
Title:	Activation of PI3K/AKT and MAPK pathway through a PDGFRbeta-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma.
Author:	Li, Quan-Lin\|Gu, Fang-Ming\|Wang, Zheng\|Jiang, Jia-Hao\|Yao, Li-Qing\|Tan, Chang-Jun\|Huang, Xiao-Yong\|Ke, Ai-Wu\|Dai, Zhi\|Fan, Jia\|Zhou, Jian
PMID:	22428038

195.
Journal:	Hepatobiliary Pancreat Dis Int. 2012 Apr;11(2):177-84.
Title:	Prognostic significance and clinical relevance of Sprouty 2 protein expression in human hepatocellular carcinoma.
Author:	Song, Kang\|Gao, Qiang\|Zhou, Jian\|Qiu, Shuang-Jian\|Huang, Xiao-Wu\|Wang, Xiao-Ying\|Fan, Jia
PMID:	22484587

196.
Journal:	Int J Biochem Cell Biol. 2012 Aug;44(8):1351-60.
Title:	In vitro and in vivo anticarcinogenic effects of RNase MC2, a ribonuclease isolated from dietary bitter gourd, toward human liver cancer cells.
Author:	Fang, Evandro Fei\|Zhang, Chris Zhi Yi\|Zhang, Lin\|Fong, Wing Ping\|Ng, Tzi Bun
PMID:	22554586

197.
Journal:	Apoptosis. 2012 Aug;17(8):784-96.
Title:	Release of overexpressed CypB activates ERK signaling through CD147 binding for hepatoma cell resistance to oxidative stress.
Author:	Kim, Kiyoon\|Kim, Hunsung\|Jeong, Kwon\|Jung, Min Hyung\|Hahn, Bum-Soo\|Yoon, Kyung-Sik\|Jin, Byung Kwan\|Jahng, Geon-Ho\|Kang, Insug\|Ha, Joohun\|Choe, Wonchae
PMID:	22555451

198.
Journal:	Cancer Lett. 2012 Oct 28;323(2):215-22.
Title:	Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.
Author:	Ohno, Tomohiko\|Shirakami, Yohei\|Shimizu, Masahito\|Kubota, Masaya\|Sakai, Hiroyasu\|Yasuda, Yoichi\|Kochi, Takahiro\|Tsurumi, Hisashi\|Moriwaki, Hisataka
PMID:	22579649

199.
Journal:	Free Radic Biol Med. 2012 Jul 1;53(1):1-11.
Title:	Inhibition of hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells.
Author:	Shearn, Colin T\|Reigan, Philip\|Petersen, Dennis R
PMID:	22580126

200.
Journal:	EMBO Mol Med. 2012 Aug;4(8):743-60.
Title:	DIAPH3 governs the cellular transition to the amoeboid tumour phenotype.
Author:	Hager, Martin H\|Morley, Samantha\|Bielenberg, Diane R\|Gao, Sizhen\|Morello, Matteo\|Holcomb, Ilona N\|Liu, Wennuan\|Mouneimne, Ghassan\|Demichelis, Francesca\|Kim, Jayoung\|Solomon, Keith R\|Adam, Rosalyn M\|Isaacs, William B\|Higgs, Henry N\|Vessella, Robert L\|Di Vi
PMID:	22593025

201.
Journal:	Br J Cancer. 2012 Jun 5;106(12):1997-2003.
Title:	Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma.
Author:	Hagiwara, S\|Kudo, M\|Nagai, T\|Inoue, T\|Ueshima, K\|Nishida, N\|Watanabe, T\|Sakurai, T
PMID:	22596232

202.
Journal:	Chin Med J (Engl). 2012 Mar;125(6):1095-103.
Title:	Effect of environmental factors on chemoresistance of HepG2 cells by regulating hypoxia-inducible factor-1alpha.
Author:	Zhu, Hong\|Luo, Shun-feng\|Wang, Ji\|Li, Xin\|Wang, Hui\|Pu, Wang-yang\|Zhang, Hong\|Zhuang, Zhi-xiang
PMID:	22613537

203.
Journal:	Oncol Rep. 2012 Aug;28(2):511-8.
Title:	DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma.
Author:	El-Sitt, Sally\|Khalil, Bassem D\|Hanna, Samer\|El-Sabban, Marwan\|Fakhreddine, Najla\|El-Sibai, Mirvat
PMID:	22614672

204.
Journal:	Braz J Med Biol Res. 2012 Aug;45(8):721-9. Epub 2012 May 24.
Title:	Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation.
Author:	Ionta, M\|Rosa, M C\|Almeida, R B\|Freitas, V M\|Rezende-Teixeira, P\|Machado-Santelli, G M
PMID:	22618858

205.
Journal:	Biochem Biophys Res Commun. 2012 Jun 15;422(4):687-92.
Title:	Combined anti-tumor effects of IFN-alpha and sorafenib on hepatocellular carcinoma in vitro and in vivo.
Author:	Wang, Lijing\|Jia, Dongwei\|Duan, Fangfang\|Sun, Zhichao\|Liu, Xiaojuan\|Zhou, Lei\|Sun, Linlin\|Ren, Shifang\|Ruan, Yuanyuan\|Gu, Jianxin
PMID:	22634008

206.
Journal:	J Hepatol. 2012 Sep;57(3):592-9.
Title:	Erlotinib and sorafenib in an orthotopic rat model of hepatocellular carcinoma.
Author:	Sieghart, Wolfgang\|Pinter, Matthias\|Dauser, Bernhard\|Rohr-Udilova, Natalya\|Piguet, Anne-Christine\|Prager, Gerald\|Hayden, Hubert\|Dienes, Hans-Peter\|Dufour, Jean-Francois\|Peck-Radosavljevic, Markus
PMID:	22634341

207.
Journal:	Int J Oncol. 2012 Sep;41(3):969-78.
Title:	Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling.
Author:	Liang, Rong-Rui\|Zhang, Shu\|Qi, Jun-An\|Wang, Zhi-Dong\|Li, Jun\|Liu, Pei-Jun\|Huang, Chen\|Le, Xiao-Feng\|Yang, Jun\|Li, Zong-Fang
PMID:	22684543

208.
Journal:	Gastroenterology. 2012 Sep;143(3):787-798.e13.
Title:	Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
Author:	Martinez-Lopez, Nuria\|Garcia-Rodriguez, Juan L\|Varela-Rey, Marta\|Gutierrez, Virginia\|Fernandez-Ramos, David\|Beraza, Naiara\|Aransay, Ana M\|Schlangen, Karin\|Lozano, Juan Jose\|Aspichueta, Patricia\|Luka, Zigmund\|Wagner, Conrad\|Evert, Matthias\|Calvisi, Diego F
PMID:	22687285

209.
Journal:	Anticancer Res. 2012 Jul;32(7):2531-6.
Title:	The role of PI3K/mTOR inhibition in combination with sorafenib in hepatocellular carcinoma treatment.
Author:	Gedaly, Roberto\|Angulo, Paul\|Chen, Changguo\|Creasy, Kate Townsend\|Spear, Brett T\|Hundley, Jonathan\|Daily, Michael F\|Shah, Malay\|Evers, B Mark
PMID:	22753710

210.
Journal:	PLoS One. 2012;7(6):e39870.
Title:	Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo.
Author:	Zhang, Chris Zhiyi\|Pan, Yinghua\|Cao, Yun\|Lai, Paul B S\|Liu, Lili\|Chen, George Gong\|Yun, Jingping
PMID:	22761917

211.
Journal:	Asian Pac J Cancer Prev. 2012;13(4):1183-6.
Title:	Effect of insulin-like growth factor-1 on bone morphogenetic protein-2 expression in hepatic carcinoma SMMC7721 cells through the p38 MAPK signaling pathway.
Author:	Xu, Guan-Jun\|Cai, Sheng\|Wu, Jian-Bing
PMID:	22799302

212.
Journal:	Asian Pac J Cancer Prev. 2012;13(4):1457-61.
Title:	HGFK1 is associated with a better prognosis and reverses inhibition by gefitinib in NSCLC cases.
Author:	Zhou, Xiao-Hui\|Tang, Li-Na\|Yue, Lu\|Min, Da-Liu\|Yang, Yi\|Huang, Jian-An\|Shen, Zan
PMID:	22799348

213.
Journal:	Mar Drugs. 2012 Jun;10(6):1345-59.
Title:	SD118-xanthocillin X (1), a novel marine agent extracted from Penicillium commune, induces autophagy through the inhibition of the MEK/ERK pathway.
Author:	Zhao, Ying\|Chen, Huan\|Shang, Zhuo\|Jiao, Binghua\|Yuan, Bin\|Sun, Weizhang\|Wang, Bingui\|Miao, Mingyong\|Huang, Caiguo
PMID:	22822377

214.
Journal:	J Biol Chem. 2012 Oct 12;287(42):35576-88.
Title:	Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma.
Author:	Gong, Ke\|Chen, Chao\|Zhan, Yao\|Chen, Yan\|Huang, Zebo\|Li, Wenhua
PMID:	22927446

215.
Journal:	Int J Biochem Cell Biol. 2012 Dec;44(12):2212-22.
Title:	CIL-102 induces matrix metalloproteinase-2 (MMP-2)/MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability.
Author:	Liu, Wen-Hsin\|Chen, Yeh-Long\|Chang, Long-Sen
PMID:	22964005

216.
Journal:	Anticancer Res. 2012 Nov;32(11):4865-70.
Title:	Dissimilar immunohistochemical expression of ERK and AKT between paired biopsy and hepatectomy tissues of hepatocellular carcinoma.
Author:	Shao, Yu-Yun\|Chen, Chi-Long\|Ho, Ming-Chih\|Huang, Chien-Chung\|Tu, Hui-Ching\|Hsu, Chih-Hung\|Cheng, Ann-Lii
PMID:	23155253

217.
Journal:	PLoS One. 2012;7(12):e51916.
Title:	The silencing of Pokemon attenuates the proliferation of hepatocellular carcinoma cells in vitro and in vivo by inhibiting the PI3K/Akt pathway.
Author:	Lin, Chan-Chan\|Zhou, Jing-Ping\|Liu, Yun-Peng\|Liu, Jing-Jing\|Yang, Xiao-Ning\|Jazag, Amarsanaa\|Zhang, Zhi-Ping\|Guleng, Bayasi\|Ren, Jian-Lin
PMID:	23300578

218.
Journal:	Biochim Biophys Acta. 2012 Aug;1826(1):215-37.
Title:	Deregulation of signalling pathways in prognostic subtypes of hepatocellular carcinoma: novel insights from interspecies comparison.
Author:	Calvisi, Diego F\|Frau, Maddalena\|Tomasi, Maria L\|Feo, Francesco\|Pascale, Rosa M
PMID:	23393659

219.
Journal:	Age (Dordr). 2013 Jun;35(3):719-32.
Title:	Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver.
Author:	Chishti, Muhammad A\|Kaya, Namik\|Binbakheet, Al-Bandary\|Al-Mohanna, Falah\|Goyns, Malcolm H\|Colak, Dilek
PMID:	22477361

220.
Journal:	Gut. 2013 Mar;62(3):440-51.
Title:	HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas.
Author:	Xiao, Qianyi\|Qu, Kai\|Wang, Chenji\|Kong, Yahui\|Liu, Chao\|Jiang, Deke\|Saiyin, Hexige\|Jia, Fan\|Ni, Canrong\|Chen, Taoyang\|Zhang, Yuanyuan\|Zhang, Pingzhao\|Qin, Wenxin\|Sun, Qingwen\|Wang, Hongyang\|Yi, Qing\|Liu, Jun\|Huang, Haojie\|Yu, Long
PMID:	22490522

221.
Journal:	J Nutr Biochem. 2013 Feb;24(2):496-504.
Title:	The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation.
Author:	Androutsopoulos, Vasilis P\|Spandidos, Demetrios A
PMID:	22749133

222.
Journal:	J Cell Physiol. 2013 Feb;228(2):292-7.
Title:	Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: growth inhibition, quiescence, and recovery.
Author:	Carr, Brian I\|Cavallini, Aldo\|Lippolis, Catia\|D'Alessandro, Rosalba\|Messa, Caterina\|Refolo, Maria G\|Tafaro, Angela
PMID:	22777740

223.
Journal:	Curr Cancer Drug Targets. 2013 Mar;13(3):300-12.
Title:	Targeting tyrosine kinase receptors in hepatocellular carcinoma.
Author:	Muntane, Jordi\|De la Rosa, Angel J\|Docobo, Fernando\|Garcia-Carbonero, Rocio\|Padillo, Francisco J
PMID:	23016985

224.
Journal:	Carcinogenesis. 2013 Jan;34(1):38-47.
Title:	MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells.
Author:	Guegan, Jean-Philippe\|Ezan, Frederic\|Theret, Nathalie\|Langouet, Sophie\|Baffet, Georges
PMID:	23042098

225.
Journal:	Oncogene. 2013 Oct 10;32(41):4873-82.
Title:	Claudin-1 induces epithelial-mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells.
Author:	Suh, Y\|Yoon, C-H\|Kim, R-K\|Lim, E-J\|Oh, Y S\|Hwang, S-G\|An, S\|Yoon, G\|Gye, M C\|Yi, J-M\|Kim, M-J\|Lee, S-J
PMID:	23160379

226.
Journal:	Int J Oncol. 2013 Feb;42(2):556-64.
Title:	Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition.
Author:	Tanahashi, Toshiyuki\|Osada, Shinji\|Yamada, Atsuko\|Kato, Junko\|Yawata, Kazunori\|Mori, Ryutaro\|Imai, Hisashi\|Sasaki, Yoshiyuki\|Saito, Shiro\|Tanaka, Yoshihiro\|Nonaka, Kenichi\|Yoshida, Kazuhiro
PMID:	23229794

227.
Journal:	Cell Oncol (Dordr). 2013 Apr;36(2):121-9.
Title:	Restoration of klotho expression induces apoptosis and autophagy in hepatocellular carcinoma cells.
Author:	Shu, Guoshun\|Xie, Biao\|Ren, Feng\|Liu, Dong-cai\|Zhou, Jiapeng\|Li, Qinglong\|Chen, Jinhui\|Yuan, Lianwen\|Zhou, Jianping
PMID:	23248036

228.
Journal:	Oncogene. 2013 Oct 10;32(41):4871-2.
Title:	Claudin-1 as a promoter of EMT in hepatocellular carcinoma.
Author:	Stebbing, J\|Filipovic, A\|Giamas, G
PMID:	23318416

229.
Journal:	Cancer Cell Int. 2013 Jan 15;13(1):3.
Title:	MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma.
Author:	Lin, Shibo\|Hoffmann, Katrin\|Xiao, Zhi\|Jin, Nan\|Galli, Uwe\|Mohr, Elvira\|Buchler, Markus W\|Schemmer, Peter
PMID:	23320839

230.
Journal:	J Clin Invest. 2013 Feb;123(2):630-45.
Title:	Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Author:	Xu, Xiaojie\|Fan, Zhongyi\|Kang, Lei\|Han, Juqiang\|Jiang, Chengying\|Zheng, Xiaofei\|Zhu, Ziman\|Jiao, Huabo\|Lin, Jing\|Jiang, Kai\|Ding, Lihua\|Zhang, Hao\|Cheng, Long\|Fu, Hanjiang\|Song, Yi\|Jiang, Ying\|Liu, Jiahong\|Wang, Rongfu\|Du, Nan\|Ye, Qinong
PMID:	23321675

231.
Journal:	PLoS One. 2013;8(1):e53992.
Title:	Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model.
Author:	Ochoa-Callejero, Laura\|Perez-Martinez, Laura\|Rubio-Mediavilla, Susana\|Oteo, Jose A\|Martinez, Alfredo\|Blanco, Jose R
PMID:	23326556

232.
Journal:	Cell Death Dis. 2013 Feb 7;4:e489.
Title:	The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells.
Author:	Cheng, P\|Ni, Z\|Dai, X\|Wang, B\|Ding, W\|Rae Smith, A\|Xu, L\|Wu, D\|He, F\|Lian, J
PMID:	23392177

233.
Journal:	Mol Cell Proteomics. 2013 May;12(5):1335-49.
Title:	Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma.
Author:	Liu, Chia-Hung\|Chen, Tzu-Chi\|Chau, Gar-Yang\|Jan, Yi-Hua\|Chen, Chun-Houh\|Hsu, Chun-Nan\|Lin, Kuan-Ting\|Juang, Yue-Li\|Lu, Pei-Jung\|Cheng, Hui-Chuan\|Chen, Ming-Huang\|Chang, Chia-Fen\|Ting, Yu-Shan\|Kao, Cheng-Yan\|Hsiao, Michael\|Huang, Chi-Ying F
PMID:	23397142

234.
Journal:	Hepatology. 2013 Jul;58(1):205-17.
Title:	MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor beta receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma.
Author:	Yang, Hao\|Fang, Feng\|Chang, Ruimin\|Yang, Lianyue
PMID:	23401231

235.
Journal:	Carcinogenesis. 2013 Jun;34(6):1323-30.
Title:	Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
Author:	Wang, Xin\|Bai, Hua\|Zhang, Xiaodi\|Liu, Jiangzheng\|Cao, Peipei\|Liao, Nai\|Zhang, Wei\|Wang, Zhao\|Hai, Chunxu
PMID:	23404993

236.
Journal:	PLoS One. 2013;8(2):e55945.
Title:	Suppression of natural killer cells by sorafenib contributes to prometastatic effects in hepatocellular carcinoma.
Author:	Zhang, Qiang-Bo\|Sun, Hui-Chuan\|Zhang, Ke-Zhi\|Jia, Qing-An\|Bu, Yang\|Wang, Miao\|Chai, Zong-Tao\|Zhang, Quan-Bao\|Wang, Wen-Quan\|Kong, Ling-Qun\|Zhu, Xiao-dong\|Lu, Lu\|Wu, Wei-Zhong\|Wang, Lu\|Tang, Zhao-You
PMID:	23409093

237.
Journal:	J Agric Food Chem. 2013 Mar 20;61(11):2811-9.
Title:	P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo.
Author:	Chen, Li-Ching\|Lee, Wen-Sen
PMID:	23448150

238.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S517-26.
Title:	PTK787/ZK222584 combined with interferon alpha and 5-fluorouracil synergistically inhibits VEGF signaling pathway in hepatocellular carcinoma.
Author:	Katsura, Yoshiteru\|Wada, Hiroshi\|Murakami, Masahiro\|Akita, Hirofumi\|Hama, Naoki\|Kawamoto, Koichi\|Kobayashi, Shogo\|Marubashi, Shigeru\|Eguchi, Hidetoshi\|Tanemura, Masahiro\|Umeshita, Koji\|Doki, Yuichiro\|Mori, Masaki\|Nagano, Hiroaki
PMID:	23508585

239.
Journal:	Phytomedicine. 2013 Jun 15;20(8-9):743-52.
Title:	Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells.
Author:	Shi, Ming-Der\|Liao, Yi-Chen\|Shih, Yuan-Wei\|Tsai, Li-Yu
PMID:	23537747

240.
Journal:	Biochem Biophys Res Commun. 2013 Apr 26;434(1):35-41.
Title:	The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells.
Author:	Zhang, Caixia\|He, Hongwei\|Zhang, Hao\|Yu, Dongke\|Zhao, Wuli\|Chen, Yi\|Shao, Rongguang
PMID:	23545258

241.
Journal:	J Cancer Res Clin Oncol. 2013 Jul;139(7):1169-78.
Title:	Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Author:	Chen, Qiang\|Chen, Lei\|Zhao, Ren\|Yang, Xiao-dong\|Imran, Khan\|Xing, Chun-gen
PMID:	23563852

242.
Journal:	Metallomics. 2013 Jun;5(7):813-20.
Title:	Bis(acetylacetonato)-oxovanadium(iv), bis(maltolato)-oxovanadium(iv) and sodium metavanadate induce antilipolytic effects by regulating hormone-sensitive lipase and perilipin via activation of Akt.
Author:	Liu, Jing-Cheng\|Yu, You\|Wang, Gang\|Wang, Kui\|Yang, Xiao-Gai
PMID:	23576171

243.
Journal:	Cancer Sci. 2013 Jul;104(7):844-55.
Title:	Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors.
Author:	Svejda, Bernhard\|Kidd, Mark\|Timberlake, Andrew\|Harry, Kathy\|Kazberouk, Alexander\|Schimmack, Simon\|Lawrence, Ben\|Pfragner, Roswitha\|Modlin, Irvin M
PMID:	23578138

244.
Journal:	J Hepatol. 2013 Oct;59(4):830-41.
Title:	Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Author:	Frau, Maddalena\|Feo, Francesco\|Pascale, Rosa M
PMID:	23665184

245.
Journal:	BMC Cancer. 2013 May 30;13:267.
Title:	Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.
Author:	Chang, Alex Y\|Wang, Miao
PMID:	23721490

246.
Journal:	Oncol Rep. 2013 Aug;30(2):986-92.
Title:	MDA-7/IL-24 suppresses tumor adhesion and invasive potential in hepatocellular carcinoma cell lines.
Author:	Huo, Wei\|Li, Zhi-Min\|Zhu, Xiao-Min\|Bao, Yong-Ming\|An, Li-Jia
PMID:	23722307

247.
Journal:	Cell Cycle. 2013 Jul 1;12(13):1999-2010.
Title:	Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer.
Author:	Wang, Chunmei\|Cigliano, Antonio\|Delogu, Salvatore\|Armbruster, Julia\|Dombrowski, Frank\|Evert, Matthias\|Chen, Xin\|Calvisi, Diego F
PMID:	23759595

248.
Journal:	PLoS One. 2013 Jun 7;8(6):e65256.
Title:	A feedback inhibition between miRNA-127 and TGFbeta/c-Jun cascade in HCC cell migration via MMP13.
Author:	Yang, Zhihong\|Zhang, Yuxia\|Wang, Li
PMID:	23762330

249.
Journal:	Dig Dis Sci. 2013 Aug;58(8):2223-36.
Title:	Lipopolysaccharide-induced toll-like receptor 4 signaling in cancer cells promotes cell survival and proliferation in hepatocellular carcinoma.
Author:	Wang, Lili\|Zhu, Rong\|Huang, Zhiquan\|Li, Haigang\|Zhu, Hongguang
PMID:	23828139

250.
Journal:	Eur J Surg Oncol. 2013 Sep;39(9):974-80.
Title:	Prognostic impact of pERK in advanced hepatocellular carcinoma patients treated with sorafenib.
Author:	Chen, D\|Zhao, P\|Li, S Q\|Xiao, W K\|Yin, X Y\|Peng, B G\|Liang, L J
PMID:	23845703

251.
Journal:	Pharm Biol. 2013 Dec;51(12):1508-14.
Title:	Cleome arabica leaf extract has anticancer properties in human cancer cells.
Author:	Tigrine, Chafia\|Bulzomi, Pamela\|Leone, Stefano\|Bouriche, Hamama\|Kameli, Abdelkarim\|Marino, Maria
PMID:	23862683

252.
Journal:	PLoS One. 2013 Jul 17;8(7):e68981.
Title:	Silencing of Pokemon enhances caspase-dependent apoptosis via fas- and mitochondria-mediated pathways in hepatocellular carcinoma cells.
Author:	Zhang, Yu-Qin\|Xiao, Chuan-Xing\|Lin, Bi-Yun\|Shi, Ying\|Liu, Yun-Peng\|Liu, Jing-Jing\|Guleng, Bayasi\|Ren, Jian-Lin
PMID:	23874836

253.
Journal:	BMC Cancer. 2013 Jul 29;13:363.
Title:	Schedule-dependent antitumor effects of 5-fluorouracil combined with sorafenib in hepatocellular carcinoma.
Author:	Deng, Lifen\|Ren, Zhenggang\|Jia, Qingan\|Wu, Weizhong\|Shen, Hujia\|Wang, Yanhong
PMID:	23895220

254.
Journal:	Bioorg Med Chem. 2013 Sep 15;21(18):5694-706.
Title:	Exploration of N-(2-aminoethyl)piperidine-4-carboxamide as a potential scaffold for development of VEGFR-2, ERK-2 and Abl-1 multikinase inhibitor.
Author:	Jin, Feng\|Gao, Dan\|Wu, Qin\|Liu, Feng\|Chen, Yuzong\|Tan, Chunyan\|Jiang, Yuyang
PMID:	23932071

255.
Journal:	Int J Biochem Cell Biol. 2013 Nov;45(11):2501-11.
Title:	Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma.
Author:	Castro-Sanchez, Luis\|Agra, Noelia\|Llorente Izquierdo, Cristina\|Motino, Omar\|Casado, Marta\|Bosca, Lisardo\|Martin-Sanz, Paloma
PMID:	23954207

256.
Journal:	Toxicol Appl Pharmacol. 2013 Nov 1;272(3):568-78.
Title:	Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1.
Author:	Hernandez-Breijo, Borja\|Monserrat, Jorge\|Roman, Irene D\|Gonzalez-Rodriguez, Agueda\|Fernandez-Moreno, Ma Dolores\|Lobo, M Val T\|Valverde, Angela M\|Gisbert, Javier P\|Guijarro, Luis G
PMID:	23958494

257.
Journal:	Cancer Biol Ther. 2013 Nov;14(11):1059-67.
Title:	Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer.
Author:	Ai, Xi\|Wu, Yanhui\|Zhang, Wei\|Zhang, Zhanguo\|Jin, Guannan\|Zhao, Jianping\|Yu, Jingjing\|Lin, Youzhi\|Zhang, Wanguang\|Liang, Huifang\|Datta, Pran K\|Zhang, Mingzhi\|Zhang, Bixiang\|Chen, Xiaoping
PMID:	24025354

258.
Journal:	PLoS One. 2013 Sep 6;8(9):e72927.
Title:	Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway.
Author:	Chen, Kunlun\|Zhang, Shu\|Ji, Yuanyuan\|Li, Jun\|An, Peng\|Ren, Hongtao\|Liang, Rongrui\|Yang, Jun\|Li, Zongfang
PMID:	24039823

259.
Journal:	BMC Cancer. 2013 Oct 8;13:465.
Title:	Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells.
Author:	Baba, Atsushi\|Shimizu, Masahito\|Ohno, Tomohiko\|Shirakami, Yohei\|Kubota, Masaya\|Kochi, Takahiro\|Terakura, Daishi\|Tsurumi, Hisashi\|Moriwaki, Hisataka
PMID:	24103747

260.
Journal:	J Clin Endocrinol Metab. 2013 Dec;98(12):E1909-17.
Title:	Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Author:	Yang, Qi\|Ji, Meiju\|Guan, Haixia\|Shi, Bingyin\|Hou, Peng
PMID:	24106286

261.
Journal:	BMC Cancer. 2013 Oct 10;13:468.
Title:	FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801.
Author:	Yamaguchi, Fuminori\|Hirata, Yuko\|Akram, Hossain\|Kamitori, Kazuyo\|Dong, Youyi\|Sui, Li\|Tokuda, Masaaki
PMID:	24112473

262.
Journal:	PLoS One. 2013 Oct 9;8(10):e76951.
Title:	Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish.
Author:	Lu, Jeng-Wei\|Yang, Wan-Yu\|Tsai, Su-Mei\|Lin, Yueh-Min\|Chang, Pen-Heng\|Chen, Jim-Ray\|Wang, Horng-Dar\|Wu, Jen-Leih\|Jin, Shiow-Lian Catherine\|Yuh, Chiou-Hwa
PMID:	24130815

263.
Journal:	Acta Pharmacol Sin. 2013 Dec;34(12):1554-9.
Title:	Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro.
Author:	Wen, Wei-wei\|Xie, Shao\|Xin, Xian-liang\|Geng, Mei-yu\|Ding, Jian\|Chen, Yi
PMID:	24141568

264.
Journal:	J Transl Med. 2013 Oct 29;11:273.
Title:	Insufficient radiofrequency ablation promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through Akt and ERK signaling pathways.
Author:	Dong, Shuying\|Kong, Jian\|Kong, Fandong\|Kong, Jinge\|Gao, Jun\|Ke, Shan\|Wang, Shaohong\|Ding, Xuemei\|Sun, Wenbing\|Zheng, Lemin
PMID:	24168056

265.
Journal:	Mol Cancer Res. 2013 Nov;11(11):1437-47.
Title:	ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression.
Author:	Li, Xiaoran\|Bian, Ying\|Takizawa, Yuri\|Hashimoto, Tomio\|Ikoma, Toshiyuki\|Tanaka, Junzo\|Kitamura, Naomi\|Inagaki, Yutaka\|Komada, Masayuki\|Tanaka, Toshiaki
PMID:	24177224

266.
Journal:	Cell Mol Biol (Noisy-le-grand). 2013 Nov 3;Suppl 59:OL1876-81.
Title:	MECP2 promotes cell proliferation by activating ERK1/2 and inhibiting p38 activity in human hepatocellular carcinoma HEPG2 cells.
Author:	Zhao, L Y\|Zhang, J\|Guo, B\|Yang, J\|Han, J\|Zhao, X G\|Wang, X F\|Liu, L Y\|Li, Z F\|Song, T S\|Huang, C
PMID:	24199952

267.
Journal:	Eur J Med Res. 2013 Dec 4;18:52.
Title:	RNA interference targeting human integrin alpha6 suppresses the metastasis potential of hepatocellular carcinoma cells.
Author:	Lv, Guannan\|Lv, Tianjing\|Qiao, Shifeng\|Li, Wei\|Gao, Weiran\|Zhao, Xiaohui\|Wang, Jikun
PMID:	24304619

268.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2013 Nov;21(11):845-9.
Title:	[Anti-proliferation effect of sorafenib in combination with 5-FU for hepatocellular carcinoma in vitro: antagonistic performance and mechanism].
Author:	Deng, Li-fen\|Wang, Yan-hong\|Jia, Qing-an\|Ren, Zheng-gang\|Shen, Hu-jia\|Sun, Xiao-jing\|Li, Jing-huan
PMID:	24331695

269.
Journal:	Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014;158(1):39-43.
Title:	Valproate activates ERK signaling pathway in primary human hepatocytes.
Author:	Bitman, Michal\|Vrzal, Radim\|Dvorak, Zdenek\|Pavek, Petr
PMID:	23073524

270.
Journal:	Oncogene. 2014 May 22;33(21):2717-27.
Title:	Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models.
Author:	Chew, T W\|Liu, X J\|Liu, L\|Spitsbergen, J M\|Gong, Z\|Low, B C
PMID:	23812423

271.
Journal:	Hepatology. 2014 Mar;59(3):947-57.
Title:	Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis.
Author:	Chen, Wan-Ting\|Tseng, Chun-Chih\|Pfaffenbach, Kyle\|Kanel, Gary\|Luo, Biquan\|Stiles, Bangyan L\|Lee, Amy S
PMID:	24027047

272.
Journal:	Carcinogenesis. 2014 Feb;35(2):282-91.
Title:	SDF-1/CXCR4 axis promotes directional migration of colorectal cancer cells through upregulation of integrin alphavbeta6.
Author:	Wang, Ben\|Wang, Wenke\|Niu, Weibo\|Liu, Enyu\|Liu, Xiangjuan\|Wang, Jiayong\|Peng, Cheng\|Liu, Song\|Xu, Ling\|Wang, Lei\|Niu, Jun
PMID:	24085800

273.
Journal:	Scand J Gastroenterol. 2014 Jan;49(1):99-108.
Title:	The effect of hepatic progenitor cells on experimental hepatocellular carcinoma in the regenerating liver.
Author:	Shi, Ji-Hua\|Scholz, Hanne\|Huitfeldt, Henrik S\|Line, Pal-Dag
PMID:	24188385

274.
Journal:	J Cell Mol Med. 2014 Feb;18(2):218-30.
Title:	The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment.
Author:	Huang, Peixin\|Xu, Xiaojing\|Wang, Lingyan\|Zhu, Bijun\|Wang, Xiangdong\|Xia, Jingling
PMID:	24268047

275.
Journal:	J Cell Mol Med. 2014 Jan;18(1):49-58.
Title:	Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
Author:	He, Lu\|Zhou, Xinke\|Qu, Chen\|Hu, Lijuan\|Tang, Yunqiang\|Zhang, Qiong\|Liang, Min\|Hong, Jian
PMID:	24305552

276.
Journal:	Metallomics. 2014 Mar;6(3):518-31.
Title:	Interaction between 8-hydroxyquinoline ruthenium(II) complexes and basic fibroblast growth factors (bFGF): inhibiting angiogenesis and tumor growth through ERK and AKT signaling pathways.
Author:	Yang, Licong\|Zhang, Jingnan\|Wang, Chuan\|Qin, Xiuying\|Yu, Qianqian\|Zhou, Yanhui\|Liu, Jie
PMID:	24336978

277.
Journal:	Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1090-5.
Title:	Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Author:	Nakagawa, Hayato\|Hikiba, Yohko\|Hirata, Yoshihiro\|Font-Burgada, Joan\|Sakamoto, Kei\|Hayakawa, Yoku\|Taniguchi, Koji\|Umemura, Atsushi\|Kinoshita, Hiroto\|Sakitani, Kosuke\|Nishikawa, Yuji\|Hirano, Kenji\|Ikenoue, Tsuneo\|Ijichi, Hideaki\|Dhar, Debanjan\|Shibata, Wata
PMID:	24395807

278.
Journal:	BMC Cancer. 2014 Jan 27;14:43.
Title:	Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro.
Author:	Carr, Brian I\|Cavallini, Aldo\|D'Alessandro, Rosalba\|Refolo, Maria Grazia\|Lippolis, Catia\|Mazzocca, Antonio\|Messa, Caterina
PMID:	24468103

279.
Journal:	Hepatology. 2014 Jun;59(6):2238-50.
Title:	Functional genomics identified a novel protein tyrosine phosphatase receptor type F-mediated growth inhibition in hepatocarcinogenesis.
Author:	Bera, Rabindranath\|Chiou, Chih-Yung\|Yu, Ming-Chin\|Peng, Jei-Ming\|He, Chung-Ru\|Hsu, Chih-Yun\|Huang, Hsiao-Ling\|Ho, Uda Y\|Lin, Shi-Ming\|Lin, Yu-Jr\|Hsieh, Sen-Yung
PMID:	24470239

280.
Journal:	Molecules. 2014 Jan 27;19(2):1592-602.
Title:	Resveratrol-4-O-D-(2'-galloyl)-glucopyranoside isolated from Polygonum cuspidatum exhibits anti-hepatocellular carcinoma viability by inducing apoptosis via the JNK and ERK pathway.
Author:	Xie, Qichao\|Yang, Yupeng\|Wang, Zhiyi\|Chen, Fanglin\|Zhang, Anmei\|Liu, Chengcheng
PMID:	24473215

281.
Journal:	Cell Signal. 2014 May;26(5):1030-9.
Title:	Upregulation of HIF-2alpha induced by sorafenib contributes to the resistance by activating the TGF-alpha/EGFR pathway in hepatocellular carcinoma cells.
Author:	Zhao, Dali\|Zhai, Bo\|He, Changjun\|Tan, Gang\|Jiang, Xian\|Pan, Shangha\|Dong, Xuesong\|Wei, Zheng\|Ma, Lixin\|Qiao, Haiquan\|Jiang, Hongchi\|Sun, Xueying
PMID:	24486412

282.
Journal:	Clin Cancer Res. 2014 Mar 1;20(5):1274-1287.
Title:	Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo.
Author:	Chen, Chun-Han\|Chen, Mei-Chuan\|Wang, Jing-Chi\|Tsai, An-Chi\|Chen, Ching-Shih\|Liou, Jing-Ping\|Pan, Shiow-Lin\|Teng, Che-Ming
PMID:	24520095

283.
Journal:	Mol Pharm. 2014 Apr 7;11(4):1282-93.
Title:	Synergistic induction of apoptosis by methylseleninic acid and cisplatin, the role of ROS-ERK/AKT-p53 pathway.
Author:	Zhang, Yibo\|Zheng, Shanyuan\|Zheng, Jun-Sheng\|Wong, Ka-Hing\|Huang, Zhi\|Ngai, Sai-Ming\|Zheng, Wenjie\|Wong, Yum-Shing\|Chen, Tianfeng
PMID:	24555485

284.
Journal:	Oncol Rep. 2014 Apr;31(4):1669-76.
Title:	Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Author:	Zheng, Ying\|Wang, Xuemei\|Wang, Haidong\|Yan, Wei\|Zhang, Quan\|Chang, Xin
PMID:	24573150

285.
Journal:	Clin Cancer Res. 2014 May 1;20(9):2410-23.
Title:	BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma.
Author:	Breunig, Christian\|Mueller, Bernadett J\|Umansky, Ludmila\|Wahl, Kristin\|Hoffmann, Katrin\|Lehner, Frank\|Manns, Michael P\|Bantel, Heike\|Falk, Christine S
PMID:	24573550

286.
Journal:	Int J Mol Sci. 2014 Feb 26;15(3):3507-18.
Title:	HBx protein promotes oval cell proliferation by up-regulation of cyclin D1 via activation of the MEK/ERK and PI3K/Akt pathways.
Author:	Wang, Heng-Yi\|Yang, Sheng-Li\|Liang, Hui-Fang\|Li, Chang-Hai
PMID:	24577313

287.
Journal:	Cell Signal. 2014 Jun;26(6):1347-54.
Title:	MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells.
Author:	Zhou, Peng\|Huang, Gang\|Zhao, Yuanyin\|Zhong, Dan\|Xu, Zhizhen\|Zeng, Yijun\|Zhang, Yan\|Li, Song\|He, Fengtian
PMID:	24631531

288.
Journal:	Clin Cancer Res. 2014 May 15;20(10):2793-804.
Title:	A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.
Author:	Tabernero, Josep\|Elez, Maria Elena\|Herranz, Maria\|Rico, Isabel\|Prudkin, Ludmila\|Andreu, Jordi\|Mateos, Jose\|Carreras, Maria Josep\|Han, May\|Gifford, James\|Credi, Marc\|Yin, Wei\|Agarwal, Shefali\|Komarnitsky, Philip\|Baselga, Jose
PMID:	24634378

289.
Journal:	Oncol Rep. 2014 May;31(5):2377-84.
Title:	Isoquercitrin inhibits the progression of liver cancer in vivo and in vitro via the MAPK signalling pathway.
Author:	Huang, Guihong\|Tang, Bo\|Tang, Kun\|Dong, Xiaomin\|Deng, Jungang\|Liao, Luqin\|Liao, Zengzhen\|Yang, Hua\|He, Songqing
PMID:	24676882

290.
Journal:	Int J Clin Exp Pathol. 2014 Feb 15;7(3):1085-92. eCollection 2014.
Title:	RNAi screening with shRNAs against histone methylation-related genes reveals determinants of sorafenib sensitivity in hepatocellular carcinoma cells.
Author:	Li, Guang-Ming\|Wang, Yu-Gang\|Pan, Qin\|Wang, Jun\|Fan, Jian-Gao\|Sun, Chao
PMID:	24696725

291.
Journal:	Chin Med J (Engl). 2014;127(7):1211-7.
Title:	Higher intratumor than peritumor expression of DUSP6/MKP-3 is associated with recurrence after curative resection of hepatocellular carcinoma.
Author:	Yang, Bo\|Tan, Yunshan\|Sun, Huichuan\|Fan, Jia\|Tang, Zhaoyou\|Ji, Yuan
PMID:	24709168

292.
Journal:	Protein Cell. 2014 Jul;5(7):532-43.
Title:	FXYD6: a novel therapeutic target toward hepatocellular carcinoma.
Author:	Gao, Qian\|Chen, Xiongfei\|Duan, Hongxia\|Wang, Zhaoqing\|Feng, Jing\|Yang, Dongling\|Song, Lina\|Zhou, Ningxin\|Yan, Xiyun
PMID:	24715268

293.
Journal:	Asian Pac J Cancer Prev. 2014;15(6):2619-23.
Title:	EGF reverses multi-drug resistance via the p-ERK pathway in HepG2/ADM and SMMC7721/ADM hepatocellular carcinoma models.
Author:	Yan, Feng\|Bai, Li-Ping\|Gao, Hua\|Zhu, Chang-Ming\|Lin, Li\|Kang, Xiang-Peng
PMID:	24761873

294.
Journal:	Mol Cancer. 2014 Apr 30;13:98.
Title:	The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells.
Author:	Wang, Bin\|Ni, Zhenhong\|Dai, Xufang\|Qin, Liyan\|Li, Xinzhe\|Xu, Liang\|Lian, Jiqin\|He, Fengtian
PMID:	24779770

295.
Journal:	Biochimie. 2014 Aug;103:118-25.
Title:	CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition.
Author:	Wang, Feng-Ze\|Chang, Zheng-Yao\|Fei, Hong-Rong\|Yang, Ming-Feng\|Yang, Xiao-Yi\|Sun, Bao-Liang
PMID:	24793486

296.
Journal:	Oncotarget. 2014 May 15;5(9):2853-63.
Title:	Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling.
Author:	Fan, Cundong\|Zheng, Wenjie\|Fu, Xiaoyan\|Li, Xiaoling\|Wong, Yum-Shing\|Chen, Tianfeng
PMID:	24797310

297.
Journal:	Int J Oncol. 2014 Jul;45(1):177-88.
Title:	Sorafenib increases efficacy of vorinostat against human hepatocellular carcinoma through transduction inhibition of vorinostat-induced ERK/NF-kappaB signaling.
Author:	Hsu, Fei-Ting\|Liu, Yu-Chang\|Chiang, I-Tsang\|Liu, Ren-Shyan\|Wang, Hsin-Ell\|Lin, Wuu-Jyh\|Hwang, Jeng-Jong
PMID:	24807012

298.
Journal:	Oncol Rep. 2014 Jul;32(1):411-8.
Title:	Downregulation of galectin-3 causes a decrease in uPAR levels and inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells.
Author:	Zheng, Datong\|Hu, Zhenzhen\|He, Fan\|Gao, Caijie\|Xu, Lijian\|Zou, Han\|Wu, Zhiwei\|Jiang, Xiuqin\|Wang, Jianjun
PMID:	24807674

299.
Journal:	Int J Oncol. 2014 Aug;45(2):629-40.
Title:	MST4 promotes hepatocellular carcinoma epithelial-mesenchymal transition and metastasis via activation of the p-ERK pathway.
Author:	Lin, Zhen-Hai\|Wang, Liying\|Zhang, Ju-Bo\|Liu, Yanfeng\|Li, Xiao-Qiang\|Guo, Lei\|Zhang, Bo\|Zhu, Wen-Wei\|Ye, Qing-Hai
PMID:	24859810

300.
Journal:	BMC Cancer. 2014 May 21;14:351.
Title:	Antagonism of sorafenib and regorafenib actions by platelet factors in hepatocellular carcinoma cell lines.
Author:	D'Alessandro, Rosalba\|Refolo, Maria G\|Lippolis, Catia\|Giannuzzi, Grazia\|Carella, Nicola\|Messa, Caterina\|Cavallini, Aldo\|Carr, Brian I
PMID:	24885890

301.
Journal:	Eur J Pharmacol. 2014 Sep 5;738:142-52.
Title:	Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma.
Author:	Gong, Ke\|Zhang, Zhenxing\|Chen, Yicheng\|Shu, Hong-Bing\|Li, Wenhua
PMID:	24886888

302.
Journal:	Mol Med Rep. 2014 Aug;10(2):839-47.
Title:	Activated deltaopioid receptors inhibit hydrogen peroxideinduced apoptosis in liver cancer cells through the PKC/ERK signaling pathway.
Author:	Jia, Kaiqi\|Sun, Deguang\|Ling, Sunbin\|Tian, Yu\|Yang, Xuejun\|Sui, Jidong\|Tang, Bo\|Wang, Liming
PMID:	24912447

303.
Journal:	Biomaterials. 2014 Aug;35(26):7479-87.
Title:	Therapeutic effect of a multi-targeted imidazolium compound in hepatocellular carcinoma.
Author:	Gopalan, Began\|Narayanan, Karthikeyan\|Ke, Zhiyuan\|Lu, Ting\|Zhang, Yugen\|Zhuo, Lang
PMID:	24912819

304.
Journal:	FEBS Open Bio. 2014 Apr 1;4:353-61.
Title:	Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling.
Author:	Santhekadur, Prasanna K\|Akiel, Maaged\|Emdad, Luni\|Gredler, Rachel\|Srivastava, Jyoti\|Rajasekaran, Devaraja\|Robertson, Chadia L\|Mukhopadhyay, Nitai D\|Fisher, Paul B\|Sarkar, Devanand
PMID:	24918049

305.
Journal:	Oncol Lett. 2014 Jul;8(1):17-24.
Title:	High expression of erythropoietin-producing hepatoma cell line-B2 (EphB2) predicts the efficiency of the Qingyihuaji formula treatment in pancreatic cancer CFPAC-1 cells through the EphrinB1-EphB2 pathway.
Author:	Hua, Yong-Qiang\|Chen, Zhen\|Meng, Zhi-Qiang\|Chen, Hao\|Shen, Jian-Gang\|Wang, Kun\|Peng, Wang\|Shen, Ye-Hua\|Liu, Lu-Ming
PMID:	24959213

306.
Journal:	Mol Cancer. 2014 Jul 1;13:162.
Title:	Thyroid hormone enhanced human hepatoma cell motility involves brain-specific serine protease 4 activation via ERK signaling.
Author:	Chen, Cheng-Yi\|Chung, I-Hsiao\|Tsai, Ming-Ming\|Tseng, Yi-Hsin\|Chi, Hsiang-Cheng\|Tsai, Chung-Ying\|Lin, Yang-Hsiang\|Wang, You-Ching\|Chen, Chie-Pein\|Wu, Tzu-I\|Yeh, Chau-Ting\|Tai, Dar-In\|Lin, Kwang-Huei
PMID:	24980078

307.
Journal:	J Transl Med. 2014 Jul 4;12:190.
Title:	Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma.
Author:	Wu, Jiao\|Hao, Zhi-Wei\|Zhao, You-Xu\|Yang, Xiang-Min\|Tang, Hao\|Zhang, Xin\|Song, Fei\|Sun, Xiu-Xuan\|Wang, Bin\|Nan, Gang\|Chen, Zhi-Nan\|Bian, Huijie
PMID:	24996644

308.
Journal:	Zhongguo Zhong Yao Za Zhi. 2014 Apr;39(7):1276-9.
Title:	[Role of ERK/FoxO3a signal axis in inhibitory effect of vitexin 1 (VB-1) in HepG2 cell proliferation].
Author:	Zheng, Xing-Xing\|Zhang, Ren-Shuo\|Zhou, Ying-Jun\|Wang, Jian-Gang
PMID:	25011268

309.
Journal:	Int J Biol Sci. 2014 Jun 10;10(7):664-76.
Title:	Long non-coding RNA URHC regulates cell proliferation and apoptosis via ZAK through the ERK/MAPK signaling pathway in hepatocellular carcinoma.
Author:	Xu, Wei-Hua\|Zhang, Jian-Bin\|Dang, Zheng\|Li, Xiao\|Zhou, Ti\|Liu, Jie\|Wang, De-Sheng\|Song, Wen-Jie\|Dou, Ke-Feng
PMID:	25013376

310.
Journal:	Oncotarget. 2014 Jul 30;5(14):5570-80.
Title:	Small interfering RNA (siRNA)-mediated knockdown of macrophage migration inhibitory factor (MIF) suppressed cyclin D1 expression and hepatocellular carcinoma cell proliferation.
Author:	Huang, Xiao-Hui\|Jian, Wei-Hua\|Wu, Zhao-Feng\|Zhao, Jie\|Wang, Hua\|Li, Wen\|Xia, Jin-Tang
PMID:	25015194

311.
Journal:	J Biol Chem. 2014 Aug 29;289(35):24665-79.
Title:	A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation.
Author:	Shan, Jixiu\|Balasubramanian, Mukundh N\|Donelan, William\|Fu, Lingchen\|Hayner, Jaclyn\|Lopez, Maria-Cecilia\|Baker, Henry V\|Kilberg, Michael S
PMID:	25028509

312.
Journal:	Oncotarget. 2014 Jul 30;5(14):5819-31.
Title:	Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts.
Author:	Wei, Wei\|Wu, Song\|Wang, Xiaolin\|Sun, Chris Kin-Wai\|Yang, Xiaoyang\|Yan, Xinrui\|Chua, Mei-Sze\|So, Samuel
PMID:	25051375

313.
Journal:	PLoS One. 2014 Jul 31;9(7):e103828.
Title:	Endoplasmic reticulum stress activates the hepatic activator protein 1 complex via mitogen activated protein kinase-dependent signaling pathways.
Author:	Olivares, Shantel\|Green, Richard M\|Henkel, Anne S
PMID:	25077945

314.
Journal:	BMC Cancer. 2014 Aug 1;14:556.
Title:	Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling.
Author:	Tsai, Cheng-Fang\|Hsieh, Tsung-Hua\|Lee, Jau-Nan\|Hsu, Chia-Yi\|Wang, Yu-Chih\|Lai, Feng-Jie\|Kuo, Kung-Kai\|Wu, Hua-Lin\|Tsai, Eing-Mei\|Kuo, Po-Lin
PMID:	25081364

315.
Journal:	Tumour Biol. 2014 Nov;35(11):11005-11.
Title:	Inhibition of fibroblast growth factor receptor signaling impairs metastasis of hepatocellular carcinoma.
Author:	Wang, Jiajun\|Su, Hongying\|Han, Xiangjun\|Xu, Ke
PMID:	25091573

316.
Journal:	Cancer Res. 2014 Aug 15;74(16):4364-77.
Title:	AEG-1 regulates retinoid X receptor and inhibits retinoid signaling.
Author:	Srivastava, Jyoti\|Robertson, Chadia L\|Rajasekaran, Devaraja\|Gredler, Rachel\|Siddiq, Ayesha\|Emdad, Luni\|Mukhopadhyay, Nitai D\|Ghosh, Shobha\|Hylemon, Phillip B\|Gil, Gregorio\|Shah, Khalid\|Bhere, Deepak\|Subler, Mark A\|Windle, Jolene J\|Fisher, Paul B\|Sarkar, D
PMID:	25125681

317.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G749-59.
Title:	PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors.
Author:	Liu, Chunsheng\|Li, Jiachu\|Xiang, Xiaoyu\|Guo, Luyang\|Tu, Kangsheng\|Liu, Qinghua\|Shah, Vijay H\|Kang, Ningling
PMID:	25169976

318.
Journal:	Cancer Res. 2014 Nov 1;74(21):6184-93.
Title:	Genetic deletion of AEG-1 prevents hepatocarcinogenesis.
Author:	Robertson, Chadia L\|Srivastava, Jyoti\|Siddiq, Ayesha\|Gredler, Rachel\|Emdad, Luni\|Rajasekaran, Devaraja\|Akiel, Maaged\|Shen, Xue-Ning\|Guo, Chunqing\|Giashuddin, Shah\|Wang, Xiang-Yang\|Ghosh, Shobha\|Subler, Mark A\|Windle, Jolene J\|Fisher, Paul B\|Sarkar, Devana
PMID:	25193383

319.
Journal:	Yao Xue Xue Bao. 2014 Jun;49(6):861-8.
Title:	[Anti-tumor activity and mechanism of T03 in vitro and in vivo].
Author:	Tang, Ke\|Yang, Han-Ze\|Li, Yan\|Tian, Kang\|Li, Chao\|Zhou, Wan-Qi\|Niu, Fei\|Feng, Zhi-Qiang\|Chen, Xiao-Guang
PMID:	25212033

320.
Journal:	Nat Med. 2014 Oct;20(10):1138-46.
Title:	In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Author:	Rudalska, Ramona\|Dauch, Daniel\|Longerich, Thomas\|McJunkin, Katherine\|Wuestefeld, Torsten\|Kang, Tae-Won\|Hohmeyer, Anja\|Pesic, Marina\|Leibold, Josef\|von Thun, Anne\|Schirmacher, Peter\|Zuber, Johannes\|Weiss, Karl-Heinz\|Powers, Scott\|Malek, Nisar P\|Eilers, Mar
PMID:	25216638

321.
Journal:	Mol Cancer. 2014 Sep 14;13:216.
Title:	Small nucleolar RNA 113-1 suppresses tumorigenesis in hepatocellular carcinoma.
Author:	Xu, Gang\|Yang, Fang\|Ding, Cui-Ling\|Zhao, Lan-Juan\|Ren, Hao\|Zhao, Ping\|Wang, Wen\|Qi, Zhong-Tian
PMID:	25217841

322.
Journal:	Biochem Biophys Res Commun. 2014 Sep 26;452(3):801-7.
Title:	Activation of RAS/ERK alone is insufficient to inhibit RXRalpha function and deplete retinoic acid in hepatocytes.
Author:	Wang, Ai-Guo\|Song, Ya-Nan\|Chen, Jun\|Li, Hui-Ling\|Dong, Jian-Yi\|Cui, Hai-Peng\|Yao, Liang\|Li, Xue-Feng\|Gao, Wen-Ting\|Qiu, Ze-Wen\|Wang, Fu-Jin\|Wang, Jing-Yu
PMID:	25218146

323.
Journal:	Neoplasia. 2014 Aug;16(8):617-26.
Title:	Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice.
Author:	Chen, Wan-Ting\|Ha, Dat\|Kanel, Gary\|Lee, Amy S
PMID:	25220589

324.
Journal:	Oncol Lett. 2014 Nov;8(5):2333-2339.
Title:	Reversing multidrug resistance in hepatocellular carcinoma cells by inhibiting extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activity.
Author:	Chen, Siyuan\|Wang, Yali\|Ruan, Wenwen\|Wang, Xiaomin\|Pan, Chao
PMID:	25295120

325.
Journal:	Oncol Rep. 2014 Dec;32(6):2687-95.
Title:	Identification of PAQR3 as a new candidate tumor suppressor in hepatocellular carcinoma.
Author:	Wu, Hong Ge\|Zhang, Wen Jie\|Ding, Qian\|Peng, Gang\|Zou, Zhen Wei\|Liu, Ting\|Cao, Ru Bo\|Fei, Shi Jiang\|Li, Peng Cheng\|Yang, Kun Yu\|Hu, Jian Li\|Dai, Xiang Fang\|Wu, Gang\|Li, Pin Dong
PMID:	25310770

326.
Journal:	Environ Toxicol Pharmacol. 2014 Nov;38(3):959-67.
Title:	Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.
Author:	Jayasooriya, Rajapaksha Gedara Prasad Tharanga\|Choi, Yung Hyun\|Hyun, Jin Won\|Kim, Gi-Young
PMID:	25461556

327.
Journal:	Zhong Yao Cai. 2014 Nov;37(11):1938-46.
Title:	[Study on synergistic effect of sodium cantharidinate combined with chemotherapeutic drugs on hepatic carcinoma and its effective mechanism].
Author:	Zhao, Ruo-lin\|Chen, Mei-juan\|Zhao, Feng-ming\|Xu, Dong-qing\|Zhang, Xu\|Zhou, Kun-fu
PMID:	26027111

328.
Journal:	J Viral Hepat. 2015 Feb;22(2):201-11.
Title:	PCDH20 functions as a tumour-suppressor gene through antagonizing the Wnt/beta-catenin signalling pathway in hepatocellular carcinoma.
Author:	Lv, J\|Zhu, P\|Yang, Z\|Li, M\|Zhang, X\|Cheng, J\|Chen, X\|Lu, F
PMID:	24910204

329.
Journal:	Int J Cancer. 2015 Feb 15;136(4):E3-13.
Title:	Fatty liver creates a pro-metastatic microenvironment for hepatocellular carcinoma through activation of hepatic stellate cells.
Author:	Mikuriya, Yoshihiro\|Tashiro, Hirotaka\|Kuroda, Shintaro\|Nambu, Junko\|Kobayashi, Tsuyoshi\|Amano, Hironobu\|Tanaka, Yuka\|Ohdan, Hideki
PMID:	25053237

330.
Journal:	Hepatology. 2015 Jan;61(1):214-26.
Title:	FAK is required for c-Met/beta-catenin-driven hepatocarcinogenesis.
Author:	Shang, Na\|Arteaga, Maribel\|Zaidi, Ali\|Stauffer, Jimmy\|Cotler, Scott J\|Zeleznik-Le, Nancy J\|Zhang, Jiwang\|Qiu, Wei
PMID:	25163657

331.
Journal:	Mol Carcinog. 2015 Dec;54(12):1554-66.
Title:	The collagen triple helix repeat containing 1 facilitates hepatitis B virus-associated hepatocellular carcinoma progression by regulating multiple cellular factors and signal cascades.
Author:	Zhang, Rui\|Cao, Yanhua\|Bai, Lan\|Zhu, Chengliang\|Li, Rui\|He, Hui\|Liu, Yingle\|Wu, Kailang\|Liu, Fang\|Wu, Jianguo
PMID:	25263696

332.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):470-8.
Title:	Hepatitis C virus NS3 protein enhances cancer cell invasion by activating matrix metalloproteinase-9 and cyclooxygenase-2 through ERK/p38/NF-kappaB signal cascade.
Author:	Lu, Lili\|Zhang, Qi\|Wu, Kailang\|Chen, Xi\|Zheng, Yi\|Zhu, Chengliang\|Wu, Jianguo
PMID:	25305454

333.
Journal:	Int J Cancer. 2015 Jul 1;137(1):104-15.
Title:	Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling.
Author:	Ciou, Shih-Ci\|Chou, Yu-Ting\|Liu, Yu-Ling\|Nieh, Yu-Chin\|Lu, Jeng-Wei\|Huang, Shiu-Feng\|Chou, Yu-Ting\|Cheng, Li-Hao\|Lo, Jeng-Fan\|Chen, Ming-Jen\|Yang, Ming-Chi\|Yuh, Chiou-Hwa\|Wang, Horng-Dar
PMID:	25429733

334.
Journal:	Biochem Biophys Res Commun. 2015 Jan 2;456(1):86-91.
Title:	Inhibition of MEK/ERK activation attenuates autophagy and potentiates pemetrexed-induced activity against HepG2 hepatocellular carcinoma cells.
Author:	Tong, Yongxi\|Huang, Haijun\|Pan, Hongying
PMID:	25446102

335.
Journal:	Exp Cell Res. 2015 Feb 1;331(1):97-104.
Title:	Anti-tumor activity of sorafenib in a model of a pediatric hepatocellular carcinoma.
Author:	Nagel, Carmen\|Armeanu-Ebinger, Sorin\|Dewerth, Alexander\|Warmann, Steven W\|Fuchs, Jorg
PMID:	25447203

336.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):713-20.
Title:	Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin.
Author:	Song, Jin\|Ge, Zhouhong\|Yang, Xinrong\|Luo, Qin\|Wang, Cun\|You, Haiyan\|Ge, Tianxiang\|Deng, Yun\|Lin, Hechun\|Cui, Yongqi\|Chu, Wei\|Yao, Ming\|Zhang, Zhigang\|Gu, Jianren\|Fan, Jia\|Qin, Wenxin
PMID:	25449435

337.
Journal:	Biochem Pharmacol. 2015 Jan 1;93(1):110-24.
Title:	Oncogenic c-Myc and prothymosin-alpha protect hepatocellular carcinoma cells against sorafenib-induced apoptosis.
Author:	Lin, Yi-Te\|Lu, Hsing-Pang\|Chao, Chuck C-K
PMID:	25451688

338.
Journal:	Chem Biol Interact. 2015 Jun 5;234:274-81.
Title:	Down-regulation of aldo-keto reductase AKR1B10 gene expression by a phorbol ester via the ERK/c-Jun signaling pathway.
Author:	Nishinaka, Toru\|Miura, Takeshi\|Sakou, Mihoko\|Hidaka, Chiemi\|Sasaoka, Chisato\|Okamura, Asuka\|Okamoto, Atsushi\|Terada, Tomoyuki
PMID:	25463304

339.
Journal:	Ann Surg Oncol. 2015 Sep;22(9):3121-9.
Title:	TREM-1, an inflammatory modulator, is expressed in hepatocellular carcinoma cells and significantly promotes tumor progression.
Author:	Duan, Meng\|Wang, Zhi-Chao\|Wang, Xiao-Ying\|Shi, Jie-Yi\|Yang, Liu-Xiao\|Ding, Zhen-Bing\|Gao, Qiang\|Zhou, Jian\|Fan, Jia
PMID:	25465376

340.
Journal:	J Gen Virol. 2015 Mar;96(Pt 3):614-25.
Title:	C-terminal-truncated hepatitis B virus X protein enhances the development of diethylnitrosamine-induced hepatocellular carcinogenesis.
Author:	Quetier, Ivan\|Brezillon, Nicolas\|Revaud, Julien\|Ahodantin, James\|DaSilva, Lucie\|Soussan, Patrick\|Kremsdorf, Dina
PMID:	25519169

341.
Journal:	Biochim Biophys Acta. 2015 Mar;1853(3):539-48.
Title:	MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.
Author:	Shan, Jixiu\|Donelan, William\|Hayner, Jaclyn N\|Zhang, Fan\|Dudenhausen, Elizabeth E\|Kilberg, Michael S
PMID:	25523140

342.
Journal:	Carcinogenesis. 2015 Mar;36(3):378-89.
Title:	Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors.
Author:	Bopp, Anita\|Wartlick, Friedrich\|Henninger, Christian\|Schwarz, Michael\|Kaina, Bernd\|Fritz, Gerhard
PMID:	25556150

343.
Journal:	Mol Med Rep. 2015 May;11(5):3842-7.
Title:	Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor.
Author:	Shi, Shanshan\|Yuan, Chenxing\|Zhuang, Kaizan\|Liang, Guikai\|Yao, Zhangting\|Wang, Duoduo\|Weng, Qinjie\|Cao, Ji\|Luo, Peihua\|Zhu, Hong\|Ding, Ling\|Ma, Shenglin
PMID:	25607114

344.
Journal:	PLoS One. 2015 Jan 21;10(1):e0114495.
Title:	Preclinical trials for prevention of tumor progression of hepatocellular carcinoma by LZ-8 targeting c-Met dependent and independent pathways.
Author:	Wu, Jia-Ru\|Hu, Chi-Tan\|You, Ren-In\|Ma, Pei-Ling\|Pan, Siou-Mei\|Lee, Ming-Che\|Wu, Wen-Sheng
PMID:	25607934

345.
Journal:	J Hepatol. 2015 Jun;62(6):1287-95.
Title:	ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma.
Author:	Chen, Jianxiang\|Xia, Hongping\|Zhang, Xiaoqian\|Karthik, Sekar\|Pratap, Seshachalam Veerabrahma\|Ooi, London Lucien\|Hong, Wanjin\|Hui, Kam M
PMID:	25617497

346.
Journal:	Discov Med. 2015 Jan;19(102):7-14.
Title:	Novel molecular targets for diagnosis and treatment of hepatocellular carcinoma.
Author:	Ma, Lifang\|Ji, Lijuan\|Yu, Yongchun\|Wang, Jiayi
PMID:	25636956

347.
Journal:	Chem Asian J. 2015 Mar;10(3):642-52.
Title:	Rational design of selenadiazole derivatives to antagonize hyperglycemia-induced drug resistance in cancer cells.
Author:	Liu, Yuedan\|Luo, Yi\|Li, Xiaoling\|Zheng, Wenjie\|Chen, Tianfeng
PMID:	25641920

348.
Journal:	Cancer Sci. 2015 May;106(5):559-66.
Title:	Sirtuin 6 promotes transforming growth factor-beta1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence.
Author:	Feng, Xin-Xia\|Luo, Jing\|Liu, Mei\|Yan, Wei\|Zhou, Zhen-Zhen\|Xia, Yu-Jia\|Tu, Wei\|Li, Pei-Yuan\|Feng, Zuo-Hua\|Tian, De-An
PMID:	25683165

349.
Journal:	Biochim Biophys Acta. 2015 May;1853(5):929-39.
Title:	Dependence of fibroblast infiltration in tumor stroma on type IV collagen-initiated integrin signal through induction of platelet-derived growth factor.
Author:	Chen, Sheng-Yi\|Lin, Jo-Shi\|Lin, Huan-Ching\|Shan, Yan-Shen\|Cheng, Yu-Jung\|Yang, Bei-Chang
PMID:	25686533

350.
Journal:	Med Oncol. 2015 Mar;32(3):75.
Title:	The involvement of cell surface nucleolin in the initiation of CCR6 signaling in human hepatocellular carcinoma.
Author:	Qiu, Wei\|Wang, Guangyi\|Sun, Xiaodong\|Ye, Junfeng\|Wei, Feng\|Shi, Xiaoju\|Lv, Guoyue
PMID:	25698534

351.
Journal:	J Cell Physiol. 2015 Sep;230(9):2281-98.
Title:	Nexavar/Stivarga and viagra interact to kill tumor cells.
Author:	Tavallai, Mehrad\|Hamed, Hossein A\|Roberts, Jane L\|Cruickshanks, Nichola\|Chuckalovcak, John\|Poklepovic, Andrew\|Booth, Laurence\|Dent, Paul
PMID:	25704960

352.
Journal:	Cancer Prev Res (Phila). 2015 May;8(5):455-63.
Title:	Hepatitis B Virus X Protein Stabilizes Cyclin D1 and Increases Cyclin D1 Nuclear Accumulation through ERK-Mediated Inactivation of GSK-3beta.
Author:	Chen, Xiangmei\|Zhang, Ling\|Zheng, Sujun\|Zhang, Ting\|Li, Meng\|Zhang, Xiaolei\|Zeng, Zhenzhen\|McCrae, Malcolm A\|Zhao, Jingmin\|Zhuang, Hui\|Lu, Fengmin
PMID:	25712050

353.
Journal:	Anticancer Drugs. 2015 Jun;26(5):540-6.
Title:	Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases.
Author:	Yan, Yuan\|Li, Jie\|Han, Jia\|Hou, Ni\|Song, Ying\|Dong, Lei
PMID:	25714249

354.
Journal:	Eur J Pharmacol. 2015 May 5;754:105-14.
Title:	Hydroxysafflor yellow A inhibits angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-kappaB signaling pathway in H22 tumor-bearing mice.
Author:	Yang, Fangfang\|Li, Jingmin\|Zhu, Jinhui\|Wang, Dong\|Chen, Shaoshui\|Bai, Xianyong
PMID:	25720342

355.
Journal:	FEBS Lett. 2015 Apr 2;589(8):897-903.
Title:	Msi1 confers resistance to TRAIL by activating ERK in liver cancer cells.
Author:	Liu, Nianli\|Chen, Tianran\|Wang, Xiaohong\|Yang, Darong\|Xue, Binbin\|Zhu, Haizhen
PMID:	25747387

356.
Journal:	Int J Cancer. 2015 Sep 15;137(6):1341-51.
Title:	Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications.
Author:	Liao, Yi-Jen\|Fang, Cheng-Chieh\|Yen, Chia-Hung\|Hsu, Shih-Ming\|Wang, Chung-Kwe\|Huang, Shiu-Feng\|Liang, Yu-Chih\|Lin, Ying-Yu\|Chu, Yu-Tseng\|Arthur Chen, Yi-Ming
PMID:	25754535

357.
Journal:	Oncotarget. 2015 Apr 10;6(10):7899-917.
Title:	Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway.
Author:	Wang, Feng\|Ying, Hou-Qun\|He, Bang-Shun\|Pan, Yu-Qin\|Deng, Qi-Wen\|Sun, Hui-Ling\|Chen, Jie\|Liu, Xian\|Wang, Shu-Kui
PMID:	25760077

358.
Journal:	Cell Signal. 2015 Jul;27(7):1544-55.
Title:	PKCepsilon-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2.
Author:	Hu, Chi-Tan\|Cheng, Chuan-Chu\|Wu, Jia-Ru\|Pan, Siou-Mei\|Wu, Wen-Sheng
PMID:	25778903

359.
Journal:	Tumour Biol. 2015 Aug;36(8):6173-9.
Title:	Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells.
Author:	Sui, Zhenghui\|Zhou, Jiahua\|Cheng, Zhangjun\|Lu, Penhua
PMID:	25787749

360.
Journal:	Oncotarget. 2015 Mar 20;6(8):6406-21.
Title:	Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP.
Author:	Chen, Yong\|Liu, Ju Mei\|Xiong, Xin Xin\|Qiu, Xin Yao\|Pan, Feng\|Liu, Di\|Lan, Shu Jue\|Jin, Si\|Yu, Shang Bin\|Chen, Xiao Qian
PMID:	25788268

361.
Journal:	Am J Pathol. 2015 Apr;185(4):1135-44.
Title:	Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
Author:	Peng, Hui\|Li, Tony W H\|Yang, Heping\|Moyer, Mary P\|Mato, Jose M\|Lu, Shelly C
PMID:	25794709

362.
Journal:	Tumour Biol. 2015 Aug;36(8):6507-13.
Title:	Aflatoxin B1 induces Src phosphorylation and stimulates lung cancer cell migration.
Author:	Cui, Anguo\|Hua, Hui\|Shao, Ting\|Song, Peiying\|Kong, Qingbin\|Luo, Ting\|Jiang, Yangfu
PMID:	25820822

363.
Journal:	PLoS One. 2015 Mar 30;10(3):e0119512.
Title:	Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.
Author:	Tahtouh, Roula\|Azzi, Anne-Sophie\|Alaaeddine, Nada\|Chamat, Soulaima\|Bouharoun-Tayoun, Hasnaa\|Wardi, Layal\|Raad, Issam\|Sarkis, Riad\|Antoun, Najibe Abou\|Hilal, George
PMID:	25822740

364.
Journal:	Oncotarget. 2015 Apr 20;6(11):9355-69.
Title:	Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development.
Author:	Deng, Rong\|Zhao, Xian\|Qu, YingYing\|Chen, Cheng\|Zhu, Changhong\|Zhang, Hailong\|Yuan, Haihua\|Jin, Hui\|Liu, Xin\|Wang, Yanli\|Chen, Qin\|Huang, Jian\|Yu, Jianxiu
PMID:	25823821

365.
Journal:	Oncotarget. 2015 Apr 30;6(12):10102-15.
Title:	Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver.
Author:	Li, Xiaolei\|Tao, Junyan\|Cigliano, Antonio\|Sini, Marcella\|Calderaro, Julien\|Azoulay, Daniel\|Wang, Chunmei\|Liu, Yan\|Jiang, Lijie\|Evert, Katja\|Demartis, Maria I\|Ribback, Silvia\|Utpatel, Kirsten\|Dombrowski, Frank\|Evert, Matthias\|Calvisi, Diego F\|Chen, Xin
PMID:	25826091

366.
Journal:	Oncotarget. 2015 May 10;6(13):11627-39.
Title:	psi-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.
Author:	Ding, Jin\|Wen, Wen\|Xiang, Daimin\|Yin, Peipei\|Liu, Yanfang\|Liu, Chang\|He, Guoping\|Cheng, Zhuo\|Yin, Jianpeng\|Sheng, Chunquan\|Zhang, Wen\|Nan, Fajun\|Ye, Wencai\|Zhang, Xiuli\|Wang, Hongyang
PMID:	25890498

367.
Journal:	Biochem Biophys Res Commun. 2015 Jun 5;461(3):513-8.
Title:	Differences in antiproliferative effect of STAT3 inhibition in HCC cells with versus without HBV expression.
Author:	Hong, Yun\|Zhou, Lin\|Xie, Haiyang\|Wang, Weilin\|Zheng, Shusen
PMID:	25899746

368.
Journal:	J Agric Food Chem. 2015 May 13;63(18):4561-9.
Title:	Antcin K, an Active Triterpenoid from the Fruiting Bodies of Basswood-Cultivated Antrodia cinnamomea, Inhibits Metastasis via Suppression of Integrin-Mediated Adhesion, Migration, and Invasion in Human Hepatoma Cells.
Author:	Huang, Ya-Ling\|Chu, Yung-Lin\|Ho, Chi-Tang\|Chung, Jing-Gung\|Lai, Chiao-I\|Su, Yu-Cheng\|Kuo, Yueh-Hsiung\|Sheen, Lee-Yan
PMID:	25911944

369.
Journal:	Nutr Cancer. 2015;67(5):748-60.
Title:	Tetrahydro Iso-Alpha Acids and Hexahydro Iso-Alpha Acids from Hops Inhibit Proliferation of Human Hepatocarcinoma Cell Lines and Reduce Diethylnitrosamine Induced Liver Tumor Formation in Rats.
Author:	Starkel, Peter\|De Saeger, Christine\|Delire, Benedicte\|Magat, Julie\|Jordan, Benedicte\|Konda, Veera R\|Tripp, Mathew L\|Borbath, Ivan
PMID:	25941903

370.
Journal:	Oncotarget. 2015 Jun 20;6(17):15209-21.
Title:	Accelerated hepatocellular carcinoma development in CUL4B transgenic mice.
Author:	Yuan, Jupeng\|Jiang, Baichun\|Zhang, Aizhen\|Qian, Yanyan\|Tan, Haining\|Gao, Jiangang\|Shao, Changshun\|Gong, Yaoqin
PMID:	25945838

371.
Journal:	Oncotarget. 2015 Aug 7;6(22):19055-69.
Title:	Galpha12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4alpha inactivation, which causes c-Met induction.
Author:	Yang, Yoon Mee\|Lee, Chan Gyu\|Koo, Ja Hyun\|Kim, Tae Hyun\|Lee, Jung Min\|An, Jihyun\|Kim, Kang Mo\|Kim, Sang Geon
PMID:	25965999

372.
Journal:	J Hepatol. 2015 Oct;63(4):863-73.
Title:	EDIL3 is a novel regulator of epithelial-mesenchymal transition controlling early recurrence of hepatocellular carcinoma.
Author:	Xia, Hongping\|Chen, Jianxiang\|Shi, Ming\|Gao, Hengjun\|Sekar, Karthik\|Seshachalam, Veerabrahma Pratap\|Ooi, London Lucien P J\|Hui, Kam M
PMID:	25980764

373.
Journal:	Cell Signal. 2015 Sep;27(9):1694-702.
Title:	CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and betaTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells.
Author:	Tang, Xun\|Chen, Xianzhen\|Xu, Yanfeng\|Qiao, Yongxia\|Zhang, Xiao\|Wang, Yulan\|Guan, Yu\|Sun, Fenyong\|Wang, Jiayi
PMID:	26004137

374.
Journal:	Mol Med Rep. 2015 Sep;12(3):3890-3894.
Title:	Splicing factor 2/alternative splicing factor contributes to extracellular signalregulated kinase activation in hepatocellular carcinoma cells.
Author:	Zhao, Yawei\|Zhu, Ting\|Zhang, Xueying\|Wang, Qingyang\|Zhang, Jiyan\|Ji, Wenbin\|Ma, Yuanfang
PMID:	26018840

375.
Journal:	Liver Cancer. 2015 Mar;4(2):115-25.
Title:	Phase I trial of sorafenib following liver transplantation in patients with high-risk hepatocellular carcinoma.
Author:	Siegel, Abby B\|El-Khoueiry, Anthony B\|Finn, Richard S\|Guthrie, Katherine A\|Goyal, Abhishek\|Venook, Alan P\|Blanke, Charles D\|Verna, Elizabeth C\|Dove, Lorna\|Emond, Jean\|Kato, Tomoaki\|Samstein, Benjamin\|Busuttil, Ronald\|Remotti, Helen\|Coffey, Amy\|Brown, Robe
PMID:	26020033

376.
Journal:	Dig Dis Sci. 2015 Aug;60(8):2360-72.
Title:	TPX2 Level Correlates with Hepatocellular Carcinoma Cell Proliferation, Apoptosis, and EMT.
Author:	Liang, Bo\|Jia, Chunhong\|Huang, Yu\|He, Hua\|Li, Jialu\|Liao, Hui\|Liu, Xiao\|Liu, Xincheng\|Bai, Xiaochun\|Yang, Dinghua
PMID:	26025609

377.
Journal:	Oncotarget. 2015 Aug 28;6(25):20964-76.
Title:	Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma.
Author:	Chan, Lo-Kong\|Chiu, Yung-Tuen\|Sze, Karen Man-Fong\|Ng, Irene Oi-Lin
PMID:	26035355

378.
Journal:	World J Hepatol. 2015 May 18;7(8):1105-11.
Title:	Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin.
Author:	Ampuero, Javier\|Romero-Gomez, Manuel
PMID:	26052399

379.
Journal:	Clin Cancer Res. 2015 Oct 1;21(19):4420-30.
Title:	Hepatitis B Virus X Protein (HBx) Is Responsible for Resistance to Targeted Therapies in Hepatocellular Carcinoma: Ex Vivo Culture Evidence.
Author:	Huang, Pinbo\|Zhuang, Baoxiong\|Zhang, Heyun\|Yan, Haiyan\|Xiao, Zhiyu\|Li, Wenbin\|Zhang, Jianlong\|Tang, Qibin\|Hu, Kaishun\|Koeffler, H Phillip\|Wang, Jie\|Yin, Dong
PMID:	26059188

380.
Journal:	Mol Cell Biochem. 2015 Sep;407(1-2):223-37.
Title:	Myricetin induces apoptosis by inhibiting P21 activated kinase 1 (PAK1) signaling cascade in hepatocellular carcinoma.
Author:	Iyer, Soumya C\|Gopal, Ashidha\|Halagowder, Devaraj
PMID:	26104578

381.
Journal:	ACS Appl Mater Interfaces. 2015 Jul 15;7(27):14933-45.
Title:	Functionalized Multiwalled Carbon Nanotubes as Carriers of Ruthenium Complexes to Antagonize Cancer Multidrug Resistance and Radioresistance.
Author:	Wang, Ni\|Feng, Yanxian\|Zeng, Lilan\|Zhao, Zhennan\|Chen, Tianfeng
PMID:	26107995

382.
Journal:	Food Funct. 2015 Aug;6(8):2588-97.
Title:	Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells.
Author:	Zhang, Tian-Tian\|Yang, Li\|Jiang, Jian-Guo
PMID:	26119846

383.
Journal:	J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2):297-306.
Title:	INHIBITORY EFFECT OF TETRAMETHYLPYRAZINE ON HEPATOCELLULAR CARCINOMA: POSSIBLE ROLE OF APOPTOSIS AND CELL CYCLE ARREST.
Author:	Cao, J\|Miao, Q\|Zhang, J\|Miao, S\|Bi, L\|Zhang, S\|Yang, Q\|Zhou, X\|Zhang, M\|Xie, Y\|Wang, S
PMID:	26122217

384.
Journal:	J Breast Cancer. 2015 Jun;18(2):112-8.
Title:	Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells.
Author:	Zhang, Xuenong\|Luo, Weiwei\|Zhao, Wenwen\|Lu, Jinjian\|Chen, Xiuping
PMID:	26155286

385.
Journal:	Tumour Biol. 2015 Dec;36(12):9779-88.
Title:	MicroRNA-133a functions as a tumor suppressor by targeting IGF-1R in hepatocellular carcinoma.
Author:	Zhang, Wei\|Liu, Kai\|Liu, Songyang\|Ji, Bai\|Wang, Yingchao\|Liu, Yahui
PMID:	26156803

386.
Journal:	Evid Based Complement Alternat Med. 2015;2015:171356.
Title:	Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Author:	Zhang, Chengshuo\|Zhang, Jialin\|Li, Xin\|Sun, Ning\|Yu, Rui\|Zhao, Bochao\|Yu, Dongyang\|Cheng, Ying\|Liu, Yongfeng
PMID:	26229542

387.
Journal:	PLoS One. 2015 Jul 31;10(7):e0133264.
Title:	HCV NS5A Up-Regulates COX-2 Expression via IL-8-Mediated Activation of the ERK/JNK MAPK Pathway.
Author:	Chen, Wei-Chun\|Tseng, Chin-Kai\|Chen, Yen-Hsu\|Lin, Chun-Kuang\|Hsu, Shih-Hsien\|Wang, Shen-Nien\|Lee, Jin-Ching
PMID:	26231035

388.
Journal:	World J Hepatol. 2015 Jul 28;7(15):1964-70.
Title:	Mechanisms of hepatocellular carcinoma and challenges and opportunities for molecular targeted therapy.
Author:	Chen, Chuan\|Wang, Ge
PMID:	26244070

389.
Journal:	Cancer Lett. 2015 Nov 1;368(1):126-34.
Title:	Matrine derivative WM130 inhibits hepatocellular carcinoma by suppressing EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author:	Qian, Liqiang\|Liu, Yan\|Xu, Yang\|Ji, Weidan\|Wu, Qiuye\|Liu, Yongjing\|Gao, Quangen\|Su, Changqing
PMID:	26259512

390.
Journal:	Oncotarget. 2015 Sep 29;6(29):27252-66.
Title:	TLR3 agonist and Sorafenib combinatorial therapy promotes immune activation and controls hepatocellular carcinoma progression.
Author:	Ho, Victor\|Lim, Tong Seng\|Lee, Justin\|Steinberg, Jeffrey\|Szmyd, Radoslaw\|Tham, Muly\|Yaligar, Jadegoud\|Kaldis, Philipp\|Abastado, Jean-Pierre\|Chew, Valerie
PMID:	26287667

391.
Journal:	J Proteomics. 2015 Oct 14;128:262-71.
Title:	Comparative analysis of primary hepatocellular carcinoma with single and multiple lesions by iTRAQ-based quantitative proteomics.
Author:	Xing, Xiaohua\|Huang, Yao\|Wang, Sen\|Chi, Minhui\|Zeng, Yongyi\|Chen, Lihong\|Li, Ling\|Zeng, Jinhua\|Lin, Minjie\|Han, Xiao\|Liu, Xiaolong\|Liu, Jingfeng
PMID:	26300425

392.
Journal:	Cell Physiol Biochem. 2015;37(1):361-74.
Title:	8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.
Author:	Yang, Huan\|Xiong, Jing\|Luo, Wenjing\|Yang, Jian\|Xi, Tao
PMID:	26316083

393.
Journal:	Oncol Rep. 2015 Nov;34(5):2602-8.
Title:	Hexane extract from Sargassum serratifolium inhibits the cell proliferation and metastatic ability of human glioblastoma U87MG cells.
Author:	Kang, Chang-Won\|Park, Min-Seok\|Kim, Nan-Hee\|Lee, Ji-Hyun\|Oh, Chul-Woong\|Kim, Hyeung-Rak\|Kim, Gun-Do
PMID:	26323587

394.
Journal:	J Exp Clin Cancer Res. 2015 Sep 11;34:101.
Title:	DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1.
Author:	Xie, Binhui\|Lin, Weihao\|Ye, Junming\|Wang, Xiaonong\|Zhang, Bing\|Xiong, Shiqiu\|Li, Heping\|Tan, Guosheng
PMID:	26362312

395.
Journal:	Oncotarget. 2015 Oct 20;6(32):33658-74.
Title:	GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma.
Author:	Gu, Yan-jiao\|Li, Hong-dan\|Zhao, Liang\|Zhao, Song\|He, Wu-bin\|Rui, Li\|Su, Chang\|Zheng, Hua-chuan\|Su, Rong-jian
PMID:	26378040

396.
Journal:	Mar Drugs. 2015 Sep 24;13(10):6064-81.
Title:	Astaxanthin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells via Inhibition of Nf-Kappab P65 and Wnt/Beta-Catenin in Vitro.
Author:	Li, Jingjing\|Dai, Weiqi\|Xia, Yujing\|Chen, Kan\|Li, Sainan\|Liu, Tong\|Zhang, Rong\|Wang, Jianrong\|Lu, Wenxia\|Zhou, Yuqing\|Yin, Qin\|Abudumijiti, Huerxidan\|Chen, Rongxia\|Zheng, Yuanyuan\|Wang, Fan\|Lu, Jie\|Zhou, Yingqun\|Guo, Chuanyong
PMID:	26404320

397.
Journal:	Oncotarget. 2015 Dec 8;6(39):42040-52.
Title:	Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma.
Author:	Zhang, Jiangbo\|Cheng, Jin\|Zeng, Zhenzhen\|Wang, Yongfeng\|Li, Xiaojun\|Xie, Qing\|Jia, Junqiao\|Yan, Ying\|Guo, Zhengyang\|Gao, Jian\|Yao, Mingjie\|Chen, Xiangmei\|Lu, Fengmin
PMID:	26547929

398.
Journal:	J Exp Clin Cancer Res. 2015 Nov 11;34:138.
Title:	Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice.
Author:	Li, Xinli\|Liu, Chun\|Ip, Blanche C\|Hu, Kang-Quan\|Smith, Donald E\|Greenberg, Andrew S\|Wang, Xiang-Dong
PMID:	26560698

399.
Journal:	World J Gastroenterol. 2015 Nov 14;21(42):12059-70.
Title:	Sorafenib-based combined molecule targeting in treatment of hepatocellular carcinoma.
Author:	Gao, Jian-Jun\|Shi, Zhen-Yan\|Xia, Ju-Feng\|Inagaki, Yoshinori\|Tang, Wei
PMID:	26576091

400.
Journal:	J Agric Food Chem. 2015 Dec 9;63(48):10388-98.
Title:	Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma.
Author:	Tsai, Cheng-Fang\|Hsieh, Tsung-Hua\|Lee, Jau-Nan\|Hsu, Chia-Yi\|Wang, Yu-Chih\|Kuo, Kung-Kai\|Wu, Hua-Lin\|Chiu, Chien-Chih\|Tsai, Eing-Mei\|Kuo, Po-Lin
PMID:	26585812

401.
Journal:	PLoS One. 2015 Dec 4;10(12):e0143830.
Title:	Additive Anti-Tumor Effects of Lovastatin and Everolimus In Vitro through Simultaneous Inhibition of Signaling Pathways.
Author:	Nolting, Svenja\|Maurer, Julian\|Spottl, Gerald\|Aristizabal Prada, Elke Tatjana\|Reuther, Clemens\|Young, Karen\|Korbonits, Marta\|Goke, Burkhard\|Grossman, Ashley\|Auernhammer, Christoph J
PMID:	26636335

402.
Journal:	PLoS One. 2015 Dec 11;10(12):e0144433.
Title:	Urotensin-II-Mediated Reactive Oxygen Species Generation via NADPH Oxidase Pathway Contributes to Hepatic Oval Cell Proliferation.
Author:	Yu, XiaoTong\|Wang, PengYan\|Shi, ZhengMing\|Dong, Kun\|Feng, Ping\|Wang, HongXia\|Wang, XueJiang
PMID:	26658815

403.
Journal:	Food Nutr Res. 2015 Dec 22;59:29884.
Title:	Raf/ERK/Nrf2 signaling pathway and MMP-7 expression involvement in the trigonelline-mediated inhibition of hepatocarcinoma cell migration.
Author:	Liao, Jung Chun\|Lee, Kun Tsung\|You, Bang Jau\|Lee, Chia Lin\|Chang, Wen Te\|Wu, Yang Chang\|Lee, Hong-Zin
PMID:	26699938

404.
Journal:	Onco Targets Ther. 2015 Dec 15;8:3731-42.
Title:	GIT1 is a novel prognostic biomarker and facilitates tumor progression via activating ERK/MMP9 signaling in hepatocellular carcinoma.
Author:	Chen, Junyi\|Yang, Pinghua\|Yang, Jue\|Wen, Zhijian\|Zhang, Baohua\|Zheng, Xin
PMID:	26719701

405.
Journal:	Hepat Oncol. 2015;2(3):303-312.
Title:	The role of AEG-1 in the development of liver cancer.
Author:	Robertson, Chadia L\|Srivastava, Jyoti\|Rajasekaran, Devaraja\|Gredler, Rachel\|Akiel, Maaged A\|Jariwala, Nidhi\|Siddiq, Ayesha\|Emdad, Luni\|Fisher, Paul B\|Sarkar, Devanand
PMID:	26798451

406.
Journal:	Int J Clin Exp Pathol. 2015 Dec 1;8(12):15863-70. eCollection 2015.
Title:	Effect of halofuginone on the inhibition of proliferation and invasion of hepatocellular carcinoma HepG2 cell line.
Author:	Huo, Sibo\|Yu, Huiqiu\|Li, Chusheng\|Zhang, Jiayu\|Liu, Tongjun
PMID:	26884857

407.
Journal:	Cell Death Discov. 2015 Nov 30;1:15051.
Title:	Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling.
Author:	Tsai, M-C\|Chen, K-D\|Wang, C-C\|Huang, K-T\|Wu, C-H\|Kuo, I-Y\|Chen, L-Y\|Hu, T-H\|Goto, S\|Nakano, T\|Dorling, A\|McVey, J H\|Chen, C-L\|Lin, C-C
PMID:	27551480

408.
Journal:	Tumour Biol. 2016 Feb;37(2):2023-35.
Title:	Effect of silencing NEK2 on biological behaviors of HepG2 in human hepatoma cells and MAPK signal pathway.
Author:	Zhang, Mei-Xia\|Xu, Xi-Ming\|Zhang, Peng\|Han, Na-Na\|Deng, Jun-Jian\|Yu, Ting-Ting\|Gan, Yuan-Yuan\|He, Xiao-Qin\|Long, Zhi-Xiong
PMID:	26337275

409.
Journal:	Tumour Biol. 2016 Feb;37(2):2527-35.
Title:	Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma.
Author:	Dang, Zheng\|Shangguan, Jianying\|Zhang, Chao\|Hu, Peng\|Ren, Yanshun\|Lv, Zhicheng\|Xiang, Hongjun\|Wang, Xianghui
PMID:	26386721

410.
Journal:	Cancer Lett. 2016 Jan 1;370(1):1-9.
Title:	Activation of signal transduction pathways during hepatic oncogenesis.
Author:	Chung, Waihong\|Kim, Miran\|de la Monte, Suzanne\|Longato, Lisa\|Carlson, Rolf\|Slagle, Betty L\|Dong, Xiaoqun\|Wands, Jack R
PMID:	26433160

411.
Journal:	Toxicol Mech Methods. 2016;26(1):11-21.
Title:	ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line.
Author:	Zhou, Yan\|Zhang, Shen\|Deng, Sijun\|Dai, Chongshan\|Tang, Shusheng\|Yang, Xiayun\|Li, Daowen\|Zhao, Kena\|Xiao, Xilong
PMID:	26446980

412.
Journal:	Oncotarget. 2016 Jan 19;7(3):2646-59.
Title:	pERK/pAkt phenotyping in circulating tumor cells as a biomarker for sorafenib efficacy in patients with advanced hepatocellular carcinoma.
Author:	Li, Jun\|Shi, Lehua\|Zhang, Xiaofeng\|Sun, Bin\|Yang, Yefa\|Ge, Naijian\|Liu, Huiying\|Yang, Xia\|Chen, Lei\|Qian, Haihua\|Wu, Mengchao\|Yin, Zhengfeng
PMID:	26544731

413.
Journal:	Int J Oncol. 2016 Jan;48(1):358-66.
Title:	Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression.
Author:	Duan, Yan\|Wong, Winnie\|Chua, Sonja Courtney\|Wee, Hwee Lin\|Lim, Seng Gee\|Chua, Boon Tin\|Ho, Han Kiat
PMID:	26573872

414.
Journal:	Toxicol In Vitro. 2016 Mar;31:86-92.
Title:	Alkaloids derived from flowers of Senna spectabilis, (-)-cassine and (-)-spectaline, have antiproliferative activity on HepG2 cells for inducing cell cycle arrest in G1/S transition through ERK inactivation and downregulation of cyclin D1 expression.
Author:	Pereira, Rodrigo Machado\|Ferreira-Silva, Guilherme Alvaro\|Pivatto, Marcos\|Santos, Luciana de Avila\|Bolzani, Vanderlan da Silva\|Chagas de Paula, Daniela Aparecida\|Oliveira, Jaqueline Carvalho de\|Viegas Junior, Claudio\|Ionta, Marisa
PMID:	26616281

415.
Journal:	Cancer Lett. 2016 Feb 1;371(1):107-16.
Title:	Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.
Author:	Zhang, Qi\|Wei, Liang\|Yang, Hongchuan\|Yang, Wanqi\|Yang, Qingyu\|Zhang, Zhuofan\|Wu, Kailang\|Wu, Jianguo
PMID:	26620707

416.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2368-76.
Title:	A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Author:	Adjei, Alex A\|Richards, Donald A\|El-Khoueiry, Anthony\|Braiteh, Fadi\|Becerra, Carlos H R\|Stephenson, Joe J Jr\|Hezel, Aram F\|Sherman, Morris\|Garbo, Lawrence\|Leffingwell, Diane P\|Iverson, Cory\|Miner, Jeffrey N\|Shen, Zancong\|Yeh, Li-Tain\|Gunawan, Sonny\|Wilson
PMID:	26644411

417.
Journal:	Cancer Lett. 2016 Feb 28;371(2):171-81.
Title:	MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways.
Author:	Xu, Yanmin\|Huang, Ji\|Ma, Leina\|Shan, Juanjuan\|Shen, Junjie\|Yang, Zhi\|Liu, Limei\|Luo, Yongli\|Yao, Chao\|Qian, Cheng
PMID:	26655273

418.
Journal:	Oncotarget. 2016 Jan 12;7(2):2009-21.
Title:	Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis.
Author:	Kato, Hiroyuki\|Naiki-Ito, Aya\|Naiki, Taku\|Suzuki, Shugo\|Yamashita, Yoriko\|Sato, Shinya\|Sagawa, Hiroyuki\|Kato, Akihisa\|Kuno, Toshiya\|Takahashi, Satoru
PMID:	26655499

419.
Journal:	Life Sci. 2016 Jan 1;144:121-8.
Title:	Identification of intracellular pathways through which TGF-beta1 upregulates URG-4/URGCP gene expression in hepatoma cells.
Author:	Tokay, Esra\|Kockar, Feray
PMID:	26657209

420.
Journal:	Tumour Biol. 2016 Jun;37(6):7589-97.
Title:	Oxymatrine synergistically enhances the inhibitory effect of 5-fluorouracil on hepatocellular carcinoma in vitro and in vivo.
Author:	Liu, Yan\|Bi, Tingting\|Dai, Wei\|Wang, Gang\|Qian, Liqiang\|Gao, Quangen\|Shen, Genhai
PMID:	26687645

421.
Journal:	Int J Oncol. 2016 Mar;48(3):1125-34.
Title:	AP-2alpha inhibits hepatocellular carcinoma cell growth and migration.
Author:	Huang, Wenhuan\|Chen, Cheng\|Liang, Zhongheng\|Qiu, Junlu\|Li, Xinxin\|Hu, Xiang\|Xiang, Shuanglin\|Ding, Xiaofeng\|Zhang, Jian
PMID:	26780928

422.
Journal:	Cell Cycle. 2016;15(4):573-83.
Title:	A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells.
Author:	Augello, Giuseppa\|Puleio, Roberto\|Emma, Maria Rita\|Cusimano, Antonella\|Loria, Guido R\|McCubrey, James A\|Montalto, Giuseppe\|Cervello, Melchiorre
PMID:	26794644

423.
Journal:	Oncotarget. 2016 Mar 1;7(9):9832-43.
Title:	RB/PLK1-dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation.
Author:	Bouhlal, Hicham\|Ouled-Haddou, Hakim\|Debuysscher, Veronique\|Singh, Amrathlal Rabbind\|Ossart, Christele\|Reignier, Aline\|Hocini, Hakim\|Fouquet, Gregory\|Al Baghami, Mohammed\|Eugenio, Melanie Simoes\|Nguyen-Khac, Eric\|Regimbeau, Jean-Marc\|Marcq, Ingrid
PMID:	26799423

424.
Journal:	Tumour Biol. 2016 Jul;37(7):9691-8.
Title:	Tumour-suppressive role of PTPN13 in hepatocellular carcinoma and its clinical significance.
Author:	Zhan, Hao\|Jiang, Jiahao\|Luo, Chubin\|Sun, Qiman\|Ke, Aiwu\|Sun, Chao\|Hu, Jinwu\|Hu, Zhiqiang\|Hu, Bo\|Zhu, Kai\|Fan, Jia\|Zhou, Jian\|Huang, Xiaowu
PMID:	26801674

425.
Journal:	Sci Signal. 2016 Feb 2;9(413):ra13.
Title:	Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.
Author:	Iwamoto, Nao\|D'Alessandro, Lorenza A\|Depner, Sofia\|Hahn, Bettina\|Kramer, Bernhard A\|Lucarelli, Philippe\|Vlasov, Artyom\|Stepath, Markus\|Bohm, Martin E\|Deharde, Daniela\|Damm, Georg\|Seehofer, Daniel\|Lehmann, Wolf D\|Klingmuller, Ursula\|Schilling, Marcel
PMID:	26838549

426.
Journal:	BMC Complement Altern Med. 2016 Feb 9;16:58.
Title:	Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways.
Author:	Zhang, Chao\|Jia, Xuejing\|Bao, Jiaolin\|Chen, Shenghui\|Wang, Kai\|Zhang, Yulin\|Li, Peng\|Wan, Jian-Bo\|Su, Huanxing\|Wang, Yitao\|Mei, Zhinan\|He, Chengwei
PMID:	26861252

427.
Journal:	Oncotarget. 2016 Mar 8;7(10):11595-608.
Title:	MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis.
Author:	Sun, Wei\|Zhang, Zhuochao\|Wang, Jianlin\|Shang, Runze\|Zhou, Liang\|Wang, Xing\|Duan, Juanli\|Ruan, Bai\|Gao, Yuan\|Dai, Bin\|Qu, Shibin\|Liu, Wei\|Ding, Rui\|Wang, Lin\|Wang, Desheng\|Dou, Kefeng
PMID:	26871477

428.
Journal:	World J Gastroenterol. 2016 Feb 14;22(6):2071-80.
Title:	Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice.
Author:	Ding, Ning\|Che, Li\|Li, Xiao-Lei\|Liu, Yan\|Jiang, Li-Jie\|Fan, Biao\|Tao, Jun-Yan\|Chen, Xin\|Ji, Jia-Fu
PMID:	26877611

429.
Journal:	Sci Rep. 2016 Feb 16;6:21260.
Title:	Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Author:	Liu, Feng\|Zhang, Wen\|Yang, Fusheng\|Feng, Tingting\|Zhou, Meng\|Yu, Yuan\|Yu, Xiuping\|Zhao, Weiming\|Yi, Fan\|Tang, Wei\|Lu, Yi
PMID:	26879559

430.
Journal:	Phytomedicine. 2016 Jan 15;23(1):42-51.
Title:	Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
Author:	Durmaz, Irem\|Guven, Ebru Bilget\|Ersahin, Tulin\|Ozturk, Mehmet\|Calis, Ihsan\|Cetin-Atalay, Rengul
PMID:	26902406

431.
Journal:	Oncotarget. 2016 Mar 29;7(13):16349-61.
Title:	AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Author:	Gao, Mei\|Kong, Qingbin\|Hua, Hui\|Yin, Yancun\|Wang, Jiao\|Luo, Ting\|Jiang, Yangfu
PMID:	26918349

432.
Journal:	PLoS One. 2016 Mar 16;11(3):e0151455.
Title:	Estradiol and Estrogen Receptor Agonists Oppose Oncogenic Actions of Leptin in HepG2 Cells.
Author:	Shen, Minqian\|Shi, Haifei
PMID:	26982332

433.
Journal:	Oncotarget. 2016 Apr 19;7(16):22674-86.
Title:	MicroRNA-630 suppresses tumor metastasis through the TGF-beta- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma.
Author:	Chen, Wei-Xun\|Zhang, Zhan-Guo\|Ding, Ze-Yang\|Liang, Hui-Fang\|Song, Jia\|Tan, Xiao-Long\|Wu, Jing-Jing\|Li, Guang-Zhen\|Zeng, Zhuo\|Zhang, Bi-Xiang\|Chen, Xiao-Ping
PMID:	26993767

434.
Journal:	Cell Oncol (Dordr). 2016 Aug;39(4):333-42.
Title:	Giganteaside D induces ROS-mediated apoptosis in human hepatocellular carcinoma cells through the MAPK pathway.
Author:	Liu, Junshan\|Wei, Xiduan\|Wu, Yafeng\|Wang, Yanni\|Qiu, Yuwen\|Shi, Junmin\|Zhou, Hongling\|Lu, Zibin\|Shao, Meng\|Yu, Linzhong\|Tong, Li
PMID:	27016209

435.
Journal:	Pharmaceuticals (Basel). 2016 Mar 24;9(2). pii: ph9020018.
Title:	A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.
Author:	Tagaram, Hephzibah Rani S\|Desai, Dhimant\|Li, Guangfu\|Liu, Dai\|Rountree, C Bart\|Gowda, Kavitha\|Berg, Arthur\|Amin, Shantu\|Staveley-O'Carroll, Kevin F\|Kimchi, Eric T
PMID:	27023566

436.
Journal:	Oncotarget. 2016 May 3;7(18):26027-41.
Title:	Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3.
Author:	Xu, Ling\|Dai, Weiqi\|Li, JingJing\|He, Lei\|Wang, Fan\|Xia, Yujing\|Chen, Kan\|Li, Sainan\|Liu, Tong\|Lu, Jie\|Zhou, Yingqun\|Wang, Yugang\|Guo, Chuanyong
PMID:	27029030

437.
Journal:	Med Oncol. 2016 May;33(5):46.
Title:	FGFR3 promotes angiogenesis-dependent metastasis of hepatocellular carcinoma via facilitating MCP-1-mediated vascular formation.
Author:	Liu, Xinyu\|Jing, Xiaoqian\|Cheng, Xi\|Ma, Ding\|Jin, Zhijian\|Yang, Weiping\|Qiu, Weihua
PMID:	27044356

438.
Journal:	Onco Targets Ther. 2016 Mar 21;9:1697-706.
Title:	Up-regulated expression of phospholipase C, beta1 is associated with tumor cell proliferation and poor prognosis in hepatocellular carcinoma.
Author:	Li, Junxiang\|Zhao, Xuya\|Wang, Dazhi\|He, Wei\|Zhang, Shuai\|Cao, Wei\|Huang, Yu\|Wang, Ling\|Zhou, Shi\|Luo, Kaijian
PMID:	27051304

439.
Journal:	Oncoimmunology. 2015 Aug 24;5(2):e1078055.
Title:	Formylpeptide receptor 1 mediates the tumorigenicity of human hepatocellular carcinoma cells.
Author:	Zhang, Liang\|Wang, Huanyu\|Yang, Tianshu\|Su, Zhifeng\|Fang, Dan\|Wang, Yafeng\|Fang, Jiazhu\|Hou, Xinwei\|Le, Yingying\|Chen, Keqiang\|Wang, Ji Ming\|Su, Shao Bo\|Lin, Qing\|Zhou, Qi
PMID:	27057451

440.
Journal:	Biochem Biophys Res Commun. 2016 May 27;474(2):330-337.
Title:	MEK-ERK inhibition potentiates WAY-600-induced anti-cancer efficiency in preclinical hepatocellular carcinoma (HCC) models.
Author:	Wang, Kaifeng\|Fan, Yaohua\|Chen, Gongying\|Wang, Zhengrong\|Kong, Dexin\|Zhang, Peng
PMID:	27107695

441.
Journal:	Oncotarget. 2016 Jul 5;7(27):41274-41284.
Title:	Sorafenib-resistant hepatocellular carcinoma stratified by phosphorylated ERK activates PD-1 immune checkpoint.
Author:	Chen, Jiang\|Ji, Tong\|Zhao, Jie\|Li, Gaofeng\|Zhang, Jian\|Jin, Renan\|Liu, Jinghua\|Liu, Xiaolong\|Liang, Xiao\|Huang, Diyu\|Xie, Anyong\|Lin, Hui\|Cang, Yong\|Cai, Xiujun
PMID:	27129180

442.
Journal:	Oncotarget. 2016 Jun 14;7(24):36767-36782.
Title:	Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways.
Author:	Cui, Shu-Xiang\|Shi, Wen-Na\|Song, Zhi-Yu\|Wang, Shu-Qing\|Yu, Xin-Feng\|Gao, Zu-Hua\|Qu, Xian-Jun
PMID:	27167344

443.
Journal:	Oncol Rep. 2016 Jul;36(1):10-22.
Title:	Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma.
Author:	Xu, Song\|Yi, Xiao-Ming\|Tang, Chao-Peng\|Ge, Jing-Ping\|Zhang, Zheng-Yu\|Zhou, Wen-Quan
PMID:	27176634

444.
Journal:	Am J Cancer Res. 2016 Jan 15;6(2):509-21. eCollection 2016.
Title:	Over expression of hyaluronan promotes progression of HCC via CD44-mediated pyruvate kinase M2 nuclear translocation.
Author:	Li, Jing-Huan\|Wang, Ying-Cong\|Qin, Cheng-Dong\|Yao, Rong-Rong\|Zhang, Rui\|Wang, Yan\|Xie, Xiao-Ying\|Zhang, Lan\|Wang, Yan-Hong\|Ren, Zheng-Gang
PMID:	27186420

445.
Journal:	Mol Cancer Ther. 2016 Jun;15(6):1227-37.
Title:	Preclinical Evaluation of AMG 337, a Highly Selective Small Molecule MET Inhibitor, in Hepatocellular Carcinoma.
Author:	Du, Zhiqiang\|Caenepeel, Sean\|Shen, Yuqing\|Rex, Karen\|Zhang, Yanni\|He, Ying\|Tang, En-Tzu\|Wang, Ouhong\|Zhong, Wenge\|Zhou, Hui\|Huang, Jacqueline\|Huang, Eric\|Hu, Liaoyuan\|Coxon, Angela\|Zhang, Mingqiang
PMID:	27196749

446.
Journal:	Oncotarget. 2016 Jul 19;7(29):45302-45316.
Title:	EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway.
Author:	Wang, Lumin\|Sun, Hongfei\|Wang, Xiaofei\|Hou, Ni\|Zhao, Lingyu\|Tong, Dongdong\|He, Kang\|Yang, Yang\|Song, Tusheng\|Yang, Jun\|Huang, Chen
PMID:	27244890

447.
Journal:	Cancer Res. 2016 Jul 15;76(14):4205-15.
Title:	Phenotypic and Signaling Consequences of a Novel Aberrantly Spliced Transcript FGF Receptor-3 in Hepatocellular Carcinoma.
Author:	Li, Ke\|Shen, Baiyong\|Cheng, Xi\|Ma, Ding\|Jing, Xiaoqian\|Liu, Xinyu\|Yang, Weiping\|Peng, Chenghong\|Qiu, Weihua
PMID:	27267910

448.
Journal:	Cell Biochem Funct. 2016 Jun;34(4):274-85.
Title:	Hepatoma-derived growth factor promotes growth and metastasis of hepatocellular carcinoma cells.
Author:	Yang, Guang-Yun\|Zhang, Ai-Qun\|Wang, Jing\|Li, Chong-Hui\|Wang, Xian-Qiang\|Pan, Ke\|Zhou, Cheng\|Dong, Jia-Hong
PMID:	27273265

449.
Journal:	Oncol Rep. 2016 Aug;36(2):961-7.
Title:	Emodin induces hepatocellular carcinoma cell apoptosis through MAPK and PI3K/AKT signaling pathways in vitro and in vivo.
Author:	Lin, Wanfu\|Zhong, Maofeng\|Yin, Huixia\|Chen, Yongan\|Cao, Qingxin\|Wang, Chen\|Ling, Changquan
PMID:	27278720

450.
Journal:	J Cancer. 2016 Jun 6;7(9):1142-51.
Title:	Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin.
Author:	Xin, Hong-Wu\|Ambe, Chenwi M\|Miller, Tyler C\|Chen, Jin-Qiu\|Wiegand, Gordon W\|Anderson, Andrew J\|Ray, Satyajit\|Mullinax, John E\|Hari, Danielle M\|Koizumi, Tomotake\|Godbout, Jessica D\|Goldsmith, Paul K\|Stojadinovic, Alexander\|Rudloff, Udo\|Thorgeirsson, Snorri
PMID:	27326258

451.
Journal:	Cell Death Dis. 2016 Jun 23;7(6):e2269.
Title:	NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance.
Author:	Emma, M R\|Iovanna, J L\|Bachvarov, D\|Puleio, R\|Loria, G R\|Augello, G\|Candido, S\|Libra, M\|Gulino, A\|Cancila, V\|McCubrey, J A\|Montalto, G\|Cervello, M
PMID:	27336713

452.
Journal:	Crit Rev Oncol Hematol. 2016 Sep;105:65-72.
Title:	Hepatocellular carcinoma: Exploring the impact of ethnicity on molecular biology.
Author:	Lamarca, Angela\|Mendiola, Marta\|Barriuso, Jorge
PMID:	27372199

453.
Journal:	Biomed Pharmacother. 2016 Oct;83:450-455.
Title:	Long noncoding RNA CCHE1 indicates a poor prognosis of hepatocellular carcinoma and promotes carcinogenesis via activation of the ERK/MAPK pathway.
Author:	Peng, Wei\|Fan, Hong
PMID:	27427851

454.
Journal:	J Exp Clin Cancer Res. 2016 Jul 18;35(1):114.
Title:	Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury.
Author:	Dong, Yinying\|Shen, Xiaoyun\|He, Mingyan\|Wu, Zhifeng\|Zheng, Qiongdan\|Wang, Yaohui\|Chen, Yuhan\|Wu, Sifan\|Cui, Jiefeng\|Zeng, Zhaochong
PMID:	27431384

455.
Journal:	J Korean Med Sci. 2016 Aug;31(8):1215-23.
Title:	OTX1 Contributes to Hepatocellular Carcinoma Progression by Regulation of ERK/MAPK Pathway.
Author:	Li, Hua\|Miao, Qian\|Xu, Chun-Wei\|Huang, Jian-Hui\|Zhou, Yue-Fen\|Wu, Mei-Juan
PMID:	27478331

456.
Journal:	Oncotarget. 2016 Oct 18;7(42):68044-68056.
Title:	Peroxiredoxin I is important for cancer-cell survival in Ras-induced hepatic tumorigenesis.
Author:	Han, Bing\|Shin, Hye-Jun\|Bak, In Seon\|Bak, Yesol\|Jeong, Ye-Lin\|Kwon, Taeho\|Park, Young-Ho\|Sun, Hu-Nan\|Kim, Cheol-Hee\|Yu, Dae-Yeul
PMID:	27517622

457.
Journal:	Biochem Biophys Res Commun. 2016 Sep 16;478(2):964-9.
Title:	Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops.
Author:	Ma, Yang\|Han, Chen-Chen\|Li, Yifan\|Wang, Yang\|Wei, Wei
PMID:	27521890

458.
Journal:	Hepatology. 2016 Nov;64(5):1637-1651.
Title:	Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma.
Author:	Chen, Hsin-An\|Kuo, Tsang-Chih\|Tseng, Chi-Feng\|Ma, Jui-Ti\|Yang, Shu-Ting\|Yen, Chia-Jui\|Yang, Ching-Yao\|Sung, Shian-Ying\|Su, Jen-Liang
PMID:	27530187

459.
Journal:	Oncotarget. 2016 Oct 11;7(41):66635-66646.
Title:	Distinct role of interleukin-6 and tumor necrosis factor receptor-1 in oval cell- mediated liver regeneration and inflammation-associated hepatocarcinogenesis.
Author:	Ji, Tong\|Li, Gaofeng\|Chen, Jiang\|Zhao, Jie\|Li, Xi\|Lin, Hui\|Cai, Xiujun\|Cang, Yong
PMID:	27556180

460.
Journal:	Sci Rep. 2016 Sep 15;6:33205.
Title:	STYK1 promotes epithelial-mesenchymal transition and tumor metastasis in human hepatocellular carcinoma through MEK/ERK and PI3K/AKT signaling.
Author:	Wang, Zhaowen\|Qu, Lei\|Deng, Biao\|Sun, Xing\|Wu, Shaohan\|Liao, Jianhua\|Fan, Junwei\|Peng, Zhihai
PMID:	27628214

461.
Journal:	BMC Cancer. 2016 Sep 21;16(1):742.
Title:	Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways.
Author:	Wang, Yu\|Nie, Hao\|Zhao, Xin\|Qin, Yong\|Gong, Xingguo
PMID:	27654866

462.
Journal:	Biomed Pharmacother. 2016 Dec;84:237-243.
Title:	Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma.
Author:	Liu, Yongdong\|Sun, Liling\|Su, Xingwang\|Guo, Sien
PMID:	27662474

463.
Journal:	EBioMedicine. 2016 Oct;12:55-67.
Title:	The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals.
Author:	Xu, Junjie\|Lin, Hui\|Li, Gonghui\|Sun, Yin\|Chen, Jiang\|Shi, Liang\|Cai, Xiujun\|Chang, Chawnshang
PMID:	27688096

464.
Journal:	Food Funct. 2016 Oct 12;7(10):4170-4174.
Title:	delta and gamma tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.
Author:	Burdeos, Gregor Carpentero\|Ito, Junya\|Eitsuka, Takahiro\|Nakagawa, Kiyotaka\|Kimura, Fumiko\|Miyazawa, Teruo
PMID:	27713963

465.
Journal:	Med Oncol. 2016 Nov;33(11):123.
Title:	Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.
Author:	Higashi, Takaaki\|Hayashi, Hiromitsu\|Kitano, Yuki\|Yamamura, Kensuke\|Kaida, Takayoshi\|Arima, Kota\|Taki, Katsunobu\|Nakagawa, Shigeki\|Okabe, Hirohisa\|Nitta, Hidetoshi\|Imai, Katsunori\|Hashimoto, Daisuke\|Chikamoto, Akira\|Beppu, Toru\|Baba, Hideo
PMID:	27734263

466.
Journal:	Oncotarget. 2016 Nov 22;7(47):76984-76994.
Title:	Phosphorylation of PPARgamma at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4.
Author:	Shu, Yuxin\|Lu, Yan\|Pang, Xiaojuan\|Zheng, Wei\|Huang, Yahong\|Li, Jiahong\|Ji, Jianguo\|Zhang, Can\|Shen, Pingping
PMID:	27769068

467.
Journal:	Am J Transl Res. 2016 Oct 15;8(10):4250-4264. eCollection 2016.
Title:	Glycosylation patterns and PHA-E-associated glycoprotein profiling associated with early hepatic encephalopathy in Chinese hepatocellular carcinoma patients.
Author:	Liu, Tian-Hua\|Liu, Deng-He\|Mo, Cui-Ju\|Sun, Lu\|Liu, Xiao-Xia\|Li, Wei\|Zhang, Shu\|Liu, Yin-Kun\|Guo, Kun
PMID:	27830009

468.
Journal:	Oncotarget. 2016 Dec 6;7(49):81223-81240.
Title:	Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into beta-arrestin-dependent ERK signaling.
Author:	Liu, Hongda\|Zhang, Qun\|Li, Kangshuai\|Gong, Zheng\|Liu, Zhaochen\|Xu, Yunfei\|Swaney, Mary Hannah\|Xiao, Kunhong\|Chen, Yuxin
PMID:	27835898

469.
Journal:	Cancer Cell. 2016 Nov 14;30(5):723-736.
Title:	ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.
Author:	Sun, Hui-Lung\|Cui, Ri\|Zhou, JianKang\|Teng, Kun-Yu\|Hsiao, Yung-Hsuan\|Nakanishi, Kotaro\|Fassan, Matteo\|Luo, Zhenghua\|Shi, Guqin\|Tili, Esmerina\|Kutay, Huban\|Lovat, Francesca\|Vicentini, Caterina\|Huang, Han-Li\|Wang, Shih-Wei\|Kim, Taewan\|Zanesi, Nicola\|Jeon, Yo
PMID:	27846390

470.
Journal:	Korean J Physiol Pharmacol. 2016 Nov;20(6):595-603.
Title:	The p90rsk-mediated signaling of ethanol-induced cell proliferation in HepG2 cell line.
Author:	Kim, Han Sang\|Kim, Su-Jin\|Bae, Jinhyung\|Wang, Yiyi\|Park, Sun Young\|Min, Young Sil\|Je, Hyun Dong\|Sohn, Uy Dong
PMID:	27847436

471.
Journal:	Oncoimmunology. 2016 Sep 20;5(10):e1226718.
Title:	Endothelial progenitor cell number and ERK phosphorylation serve as predictive and prognostic biomarkers in advanced hepatocellular carcinoma patients treated with sorafenib.
Author:	Kalathil, Suresh Gopi\|Lugade, Amit Anand\|Iyer, Renuka\|Miller, Austin\|Thanavala, Yasmin
PMID:	27853648

472.
Journal:	Sci Rep. 2016 Nov 25;6:37499.
Title:	Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Author:	Zuo, Wei-Han\|Zeng, Peng\|Chen, Xi\|Lu, Yan-Jun\|Li, An\|Wu, Jian-Bin
PMID:	27886213

473.
Journal:	World J Gastroenterol. 2016 Dec 7;22(45):10053-10063.
Title:	Smoc2 potentiates proliferation of hepatocellular carcinoma cells via promotion of cell cycle progression.
Author:	Su, Jing-Ran\|Kuai, Jing-Hua\|Li, Yan-Qing
PMID:	28018113

474.
Journal:	Front Pharmacol. 2016 Dec 21;7:490.
Title:	Grape Seed Extract Attenuates Hepatitis C Virus Replication and Virus-Induced Inflammation.
Author:	Chen, Wei-Chun\|Tseng, Chin-Kai\|Chen, Bing-Hung\|Lin, Chun-Kuang\|Lee, Jin-Ching
PMID:	28066241

475.
Journal:	Semin Cancer Biol. 2017 Feb;42:70-80.
Title:	Smyd3-associated regulatory pathways in cancer.
Author:	Giakountis, Antonis\|Moulos, Panagiotis\|Sarris, Michalis E\|Hatzis, Pantelis\|Talianidis, Iannis
PMID:	27554136

476.
Journal:	J Pineal Res. 2017 Jan;62(1).
Title:	Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma.
Author:	Sanchez, Diana I\|Gonzalez-Fernandez, Barbara\|San-Miguel, Beatriz\|de Urbina, Juan Ortiz\|Crespo, Irene\|Gonzalez-Gallego, Javier\|Tunon, Maria J
PMID:	27696512

477.
Journal:	Curr Pharm Des. 2017;23(1):170-175.
Title:	Targeting Signalling Pathways in Hepatocellular Carcinoma.
Author:	Blagotinsek, Kaja\|Rozman, Damjana
PMID:	27719638

478.
Journal:	Oncogene. 2017 Apr 6;36(14):1978-1990.
Title:	Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury.
Author:	Liao, P-H\|Hsu, H-H\|Chen, T-S\|Chen, M-C\|Day, C-H\|Tu, C-C\|Lin, Y-M\|Tsai, F-J\|Kuo, W-W\|Huang, C-Y
PMID:	27748761

479.
Journal:	Appl Microbiol Biotechnol. 2017 Feb;101(4):1535-1546.
Title:	C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells.
Author:	Jiang, Shanshan\|Wang, Qian\|Feng, Meiqing\|Li, Jiyang\|Guan, Zhongbin\|An, Duopeng\|Dong, Mengxue\|Peng, Yuzhe\|Kuerban, Kudelaidi\|Ye, Li
PMID:	27807662

480.
Journal:	Chem Biol Interact. 2017 Jan 5;261:118-126.
Title:	Didymin induces apoptosis through mitochondrial dysfunction and up-regulation of RKIP in human hepatoma cells.
Author:	Wei, Jinbin\|Huang, Quanfang\|Bai, Facheng\|Lin, Jun\|Nie, Jinlan\|Lu, Shengjuan\|Lu, Chunyuang\|Huang, Renbin\|Lu, Zhongpeng\|Lin, Xing
PMID:	27899290

481.
Journal:	Anticancer Res. 2017 Jan;37(1):87-93.
Title:	Validation of VX2 as a Hepatocellular Carcinoma Model: Comparison of the Molecular Reaction of VX2 and HepG2 Tumor Cells to Sorafenib In Vitro.
Author:	Nass, Norbert\|Streit, Sebastian\|Wybranski, Christian\|Jurgens, Julian\|Brauner, Jan\|Schulz, Nadine\|Powerski, Maciej\|Ricke, Jens\|Kalinski, Thomas\|Dudeck, Oliver\|Seidensticker, Max
PMID:	28011478

482.
Journal:	Biochem Pharmacol. 2017 Mar 1;127:90-100.
Title:	Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.
Author:	Sun, Wei-Jian\|Huang, He\|He, Bin\|Hu, Dan-Hong\|Li, Pi-Hong\|Yu, Yao-Jun\|Zhou, Xiao-Hu\|Lv, Zhen\|Zhou, Lei\|Hu, Tian-Ye\|Yao, Zhi-Chao\|Lu, Ming-Dong\|Shen, Xian\|Zheng, Zhi-Qiang
PMID:	28012958

483.
Journal:	Cancer Med. 2017 Feb;6(2):374-381.
Title:	Alendronate-anchored PEGylation of ceria nanoparticles promotes human hepatoma cell proliferation via AKT/ERK signaling pathways.
Author:	Cheng, Heng\|Liao, Zhong-Li\|Ning, Lin-Hong\|Chen, Hong-Yan\|Wei, Shan-Shan\|Yang, Xiao-Chao\|Guo, Hong
PMID:	28070935

484.
Journal:	Hepatology. 2017 Jun;65(6):1948-1962.
Title:	Polymeric immunoglobulin receptor promotes tumor growth in hepatocellular carcinoma.
Author:	Yue, Xihua\|Ai, Jing\|Xu, Yang\|Chen, Yi\|Huang, Min\|Yang, Xinying\|Hu, Bo\|Zhang, Haotian\|He, Changxi\|Yang, Xinrong\|Tang, Weiguo\|Peng, Xia\|Dong, Liwei\|Wang, Hongyang\|Fan, Jia\|Ding, Jian\|Geng, Meiyu
PMID:	28073159

485.
Journal:	Oncotarget. 2017 Feb 14;8(7):12174-12185.
Title:	NMI promotes hepatocellular carcinoma progression via BDKRB2 and MAPK/ERK pathway.
Author:	Zhao, Jing\|Dong, Qiong-Zhu\|Zhong, Fan\|Cai, Li-Li\|Qin, Zhao-Yu\|Liu, Yang\|Lin, Cheng-Zhao\|Qin, Lun-Xiu\|He, Fu-Chu
PMID:	28077802

486.
Journal:	J Cell Biochem. 2017 Aug;118(8):2357-2370.
Title:	ERK1 Directly Interacts With JNK1 Leading to Regulation of JNK1/c-Jun Activity and Cell Transformation.
Author:	Kang, Bong Seok\|Hwang, Yoon Jin\|Dong, Zigang
PMID:	28106280

487.
Journal:	Cancer Lett. 2017 Apr 28;392:1-8.
Title:	Mathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells.
Author:	Saidak, Zuzana\|Giacobbi, Anne-Sophie\|Louandre, Christophe\|Sauzay, Chloe\|Mammeri, Youcef\|Galmiche, Antoine
PMID:	28161506

488.
Journal:	Mol Oncol. 2017 Mar;11(3):320-334.
Title:	Dual inhibition of Akt and c-Met as a second-line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells.
Author:	Han, Peng\|Li, Hali\|Jiang, Xian\|Zhai, Bo\|Tan, Gang\|Zhao, Dali\|Qiao, Haiquan\|Liu, Bing\|Jiang, Hongchi\|Sun, Xueying
PMID:	28164434

489.
Journal:	Prostate. 2017 May;77(7):718-728.
Title:	Elevation of SHARPIN Protein Levels in Prostate Adenocarcinomas Promotes Metastasis and Impairs Patient Survivals.
Author:	Huang, Hai\|Du, Tao\|Zhang, Yiming\|Lai, Yiming\|Li, Kaiwen\|Fan, Xinxing\|Zhu, Dingjun\|Lin, Tianxin\|Xu, Kewei\|Huang, Jian\|Liu, Leyuan\|Guo, Zhenghui
PMID:	28230260

490.
Journal:	Discov Med. 2017 Jan;23(124):7-17.
Title:	Reduced N-acetylglucosaminyltransferase III expression via Smad3 and Erk signaling in TGF-beta1-induced HCC EMT model.
Author:	Mo, Cuiju\|Liu, Tianhua\|Zhang, Shu\|Guo, Kun\|Li, Meng\|Qin, Xue\|Liu, Yinkun
PMID:	28245423

491.
Journal:	Sci Rep. 2017 Mar 9;7:44123.
Title:	Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors.
Author:	Chen, Yunching\|Liu, Ya-Chi\|Sung, Yun-Chieh\|Ramjiawan, Rakesh R\|Lin, Ts-Ting\|Chang, Chih-Chun\|Jeng, Kuo-Shyang\|Chang, Chiung-Fang\|Liu, Chun-Hung\|Gao, Dong-Yu\|Hsu, Fu-Fei\|Duyverman, Annique M\|Kitahara, Shuji\|Huang, Peigen\|Dima, Simona\|Popescu, Irinel\|Flaher
PMID:	28276530

492.
Journal:	J Hepatol. 2017 Aug;67(2):360-369.
Title:	Mice lacking liver-specific beta-catenin develop steatohepatitis and fibrosis after iron overload.
Author:	Preziosi, Morgan E\|Singh, Sucha\|Valore, Erika V\|Jung, Grace\|Popovic, Branimir\|Poddar, Minakshi\|Nagarajan, Shanmugam\|Ganz, Tomas\|Monga, Satdarshan P
PMID:	28341391

493.
Journal:	Int J Oncol. 2017 Mar 13.
Title:	Molecular mechanism of C-reaction protein in promoting migration and invasion of hepatocellular carcinoma cells in vitro.
Author:	Shen, Shasha\|Gong, Jiaojiao\|Yang, Yixuan\|Qin, Si\|Huang, Lifan\|She, Sha\|Yang, Min\|Ren, Hong\|Hu, Huaidong
PMID:	28350119

494.
Journal:	Biomed Pharmacother. 2017 Jun;90:222-228.
Title:	Emodin targets mitochondrial cyclophilin D to induce apoptosis in HepG2 cells.
Author:	Zhang, Ling\|He, Dian\|Li, Kun\|Liu, Hongli\|Wang, Baitao\|Zheng, Lifang\|Li, Jiazhong
PMID:	28363167

495.
Journal:	PLoS Pathog. 2017 Apr 10;13(4):e1006321.
Title:	GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Author:	Zhang, Xuewu\|Zhu, Chengliang\|Wang, Tianci\|Jiang, Hui\|Ren, Yahui\|Zhang, Qi\|Wu, Kailang\|Liu, Fang\|Liu, Yingle\|Wu, Jianguo
PMID:	28394926

496.
Journal:	BMC Microbiol. 2017 Apr 13;17(1):92.
Title:	The expression of fibronectin is significantly suppressed in macrophages to exert a protective effect against Staphylococcus aureus infection.
Author:	Chen, Hong-Yi\|Lin, Mei-Hui\|Chen, Chien-Cheng\|Shu, Jwu-Ching
PMID:	28407745

497.
Journal:	Oncotarget. 2017 Apr 25;8(17):28385-28394.
Title:	Identification of DNA-PKcs as a primary resistance factor of TIC10 in hepatocellular carcinoma cells.
Author:	Cheng, Long\|Liu, Yuan-Yuan\|Lu, Pei-Hua\|Peng, Yi\|Yuan, Qiang\|Gu, Xin-Shi\|Jin, Yong\|Chen, Min-Bin\|Bai, Xu-Ming
PMID:	28415690

498.
Journal:	Oncotarget. 2017 Jul 18;8(29):47121-47135.
Title:	HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma.
Author:	Wang, Wei-Min\|Xu, Yang\|Wang, Yao-Hui\|Sun, Hai-Xiang\|Sun, Yun-Fan\|He, Yi-Feng\|Zhu, Qing-Feng\|Hu, Bo\|Zhang, Xin\|Xia, Jing-Lin\|Qiu, Shuang-Jian\|Zhou, Jian\|Yang, Xin-Rong\|Fan, Jia
PMID:	28454092

499.
Journal:	Pharmacol Res. 2017 Jul;121:145-157.
Title:	Metabotropic glutamate receptor 5 mediates the suppressive effect of 6-OHDA-induced model of Parkinson's disease on liver cancer.
Author:	Xi, Shao-Song\|Bai, Xiao-Xu\|Gu, Li\|Bao, Li-Hui\|Yang, Hui-Min\|An, Wei\|Wang, Xiao-Min\|Zhang, Hong
PMID:	28455267

500.
Journal:	Oncotarget. 2017 Apr 18;8(16):26515-26531.
Title:	The cell polarity protein Scrib functions as a tumor suppressor in liver cancer.
Author:	Kapil, Shweta\|Sharma, Bal Krishan\|Patil, Mallikarjun\|Elattar, Sawsan\|Yuan, Jinling\|Hou, Steven X\|Kolhe, Ravindra\|Satyanarayana, Ande
PMID:	28460446

501.
Journal:	Oncotarget. 2017 Apr 18;8(16):27263-27276.
Title:	SHP2 is induced by the HBx-NF-kappaB pathway and contributes to fibrosis during human early hepatocellular carcinoma development.
Author:	Kang, Hyo Jeong\|Chung, Dal-Hee\|Sung, Chang Ohk\|Yoo, Su Hyun\|Yu, Eunsil\|Kim, Nayoung\|Lee, Sy-Hye\|Song, Ji-Young\|Kim, Chong Jai\|Choi, Jene
PMID:	28460481

502.
Journal:	Oncol Res. 2017 Nov 2;25(9):1607-1616.
Title:	Inhibition of ERK1/2 Signaling Impairs the Promoting Effects of TGF-beta1 on Hepatocellular Carcinoma Cell Invasion and Epithelial-Mesenchymal Transition.
Author:	Liu, Ling\|Li, Nianfeng\|Zhang, Qi\|Zhou, Jixiang\|Lin, Ling\|He, Xinxin
PMID:	28492136

503.
Journal:	Exp Mol Pathol. 2017 Jun;102(3):492-499.
Title:	Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.
Author:	Li, Zixuan\|Qu, Lianyue\|Luo, Wenting\|Tian, Yulong\|Zhai, Huan\|Xu, Ke\|Zhong, Hongshan
PMID:	28506767

504.
Journal:	Mol Cell Proteomics. 2017 Aug;16(8):1475-1490.
Title:	Differential Proteomic Analysis of Gender-dependent Hepatic Tumorigenesis in Hras12V Transgenic Mice.
Author:	Rong, Zhuona\|Fan, Tingting\|Li, Huiling\|Li, Juan\|Wang, Kangwei\|Wang, Xinxin\|Dong, Jianyi\|Chen, Jun\|Wang, Fujin\|Wang, Jingyu\|Wang, Aiguo
PMID:	28512230

505.
Journal:	Int J Mol Sci. 2017 May 19;18(5). pii: ijms18051095.
Title:	Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.
Author:	Lee, Hanwool\|Baek, Seung Ho\|Lee, Jong Hyun\|Kim, Chulwon\|Ko, Jeong-Hyeon\|Lee, Seok-Geun\|Chinnathambi, Arunachalam\|Alharbi, Sulaiman Ali\|Yang, Woong Mo\|Um, Jae-Young\|Sethi, Gautam\|Ahn, Kwang Seok
PMID:	28534824

506.
Journal:	Oncotarget. 2017 Jul 18;8(29):47412-47424.
Title:	Effects and related mechanisms of serotonin on malignant biological behavior of hepatocellular carcinoma via regulation of Yap.
Author:	Liu, Sushun\|Miao, Runchen\|Zhai, Mimi\|Pang, Qing\|Deng, Yan\|Liu, Sinan\|Qu, Kai\|Liu, Chang\|Zhang, Jingyao
PMID:	28537892

507.
Journal:	Parasit Vectors. 2017 May 25;10(1):262.
Title:	Clonorchis sinensis granulin: identification, immunolocalization, and function in promoting the metastasis of cholangiocarcinoma and hepatocellular carcinoma.
Author:	Wang, Caiqin\|Lei, Huali\|Tian, Yanli\|Shang, Mei\|Wu, Yinjuan\|Li, Ye\|Zhao, Lu\|Shi, Mengchen\|Tang, Xin\|Chen, Tingjin\|Lv, Zhiyue\|Huang, Yan\|Tang, Xiaoping\|Yu, Xinbing\|Li, Xuerong
PMID:	28545547

508.
Journal:	Int J Oncol. 2017 Jul;51(1):128-144.
Title:	Sorafenib induces variations of the DNA methylome in HA22T/VGH human hepatocellular carcinoma-derived cells.
Author:	Abeni, Edoardo\|Salvi, Alessandro\|Marchina, Eleonora\|Traversa, Michele\|Arici, Bruna\|De Petro, Giuseppina
PMID:	28560380

509.
Journal:	Life Sci. 2017 Aug 15;183:60-68.
Title:	Pentoxifylline induces apoptosis of HepG2 cells by reducing reactive oxygen species production and activating the MAPK signaling.
Author:	Wang, Yan\|Dong, Lei\|Li, Jing\|Luo, Miaosha\|Shang, Boxin
PMID:	28583366

510.
Journal:	Immunol Lett. 2017 Aug;188:116-123.
Title:	ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma.
Author:	Xie, Yu-Xiao\|Liao, Rui\|Pan, Long\|Du, Cheng-You
PMID:	28668554

511.
Journal:	Cancer Res. 2017 Sep 1;77(17):4602-4612.
Title:	TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma.
Author:	Ng, Kai-Yu\|Chan, Lok-Hei\|Chai, Stella\|Tong, Man\|Guan, Xin-Yuan\|Lee, Nikki P\|Yuan, Yunfei\|Xie, Dan\|Lee, Terence K\|Dusetti, Nelson J\|Carrier, Alice\|Ma, Stephanie
PMID:	28674078

512.
Journal:	Int J Oncol. 2017 Sep;51(3):791-800.
Title:	Modulation of IGF2BP1 by long non-coding RNA HCG11 suppresses apoptosis of hepatocellular carcinoma cells via MAPK signaling transduction.
Author:	Xu, Yantian\|Zheng, Yuanwen\|Liu, Hongyan\|Li, Tao
PMID:	28677801

513.
Journal:	Sci Rep. 2017 Jul 11;7(1):5134.
Title:	Hydrogen sulfide acts as a double-edged sword in human hepatocellular carcinoma cells through EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author:	Wu, Dongdong\|Li, Mengling\|Tian, Wenke\|Wang, Shuaiwei\|Cui, Longzhen\|Li, Hui\|Wang, Huijuan\|Ji, Ailing\|Li, Yanzhang
PMID:	28698660

514.
Journal:	Cancer Sci. 2017 Sep;108(9):1778-1786.
Title:	Increased matrix stiffness promotes tumor progression of residual hepatocellular carcinoma after insufficient heat treatment.
Author:	Zhang, Rui\|Ma, Min\|Dong, Gang\|Yao, Rong-Rong\|Li, Jing-Huan\|Zheng, Qiong-Dan\|Dong, Yin-Ying\|Ma, Hui\|Gao, Dong-Mei\|Cui, Jie-Feng\|Ren, Zheng-Gang\|Chen, Rong-Xin
PMID:	28699238

515.
Journal:	Environ Toxicol. 2017 Nov;32(11):2360-2370.
Title:	beta-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways.
Author:	Huang, Chien-Feng\|Teng, Ying-Hock\|Lu, Fung-Jou\|Hsu, Wen-Hung\|Lin, Chia-Liang\|Hung, Chia-Chen\|Tung, Jai-Nien\|Hsieh, Yi-Hsien\|Liu, Chung-Jung
PMID:	28722351

516.
Journal:	Biomed Pharmacother. 2017 Sep;93:1025-1032.
Title:	MicroRNA-30a suppresses tumor progression by blocking Ras/Raf/MEK/ERK signaling pathway in hepatocellular carcinoma.
Author:	Zhou, Kun\|Luo, Xiaoyu\|Wang, Yu\|Cao, Dachun\|Sun, Gang
PMID:	28732393

517.
Journal:	Oncol Res. 2017 Jul 21.
Title:	MicroRNA-374a Promotes Hepatocellular Carcinoma Cell Proliferation by Targeting Mitogen-Inducible Gene-6 (MIG-6).
Author:	Li, Hui\|Chen, Huicheng\|Wang, Haibin\|Dong, Yilong\|Yin, Min\|Zhang, Liang\|Wei, Jia
PMID:	28734040

518.
Journal:	Oncogene. 2017 Nov 30;36(48):6691-6700.
Title:	Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway.
Author:	Ding, D\|Huang, H\|Jiang, W\|Yu, W\|Zhu, H\|Liu, J\|Saiyin, H\|Wu, J\|Huang, H\|Jiang, S\|Yu, L
PMID:	28745317

519.
Journal:	FASEB J. 2017 Dec;31(12):5530-5542.
Title:	Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways.
Author:	Cheng, Jianghong\|Zhong, Yanhong\|Chen, Shuai\|Sun, Yan\|Huang, Lantang\|Kang, Yujia\|Chen, Baozhen\|Chen, Gang\|Wang, Fengli\|Tian, Yingpu\|Liu, Wenjie\|Feng, Gen-Sheng\|Lu, Zhongxian
PMID:	28842424

520.
Journal:	Am J Transl Res. 2017 Aug 15;9(8):3853-3866. eCollection 2017.
Title:	The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.
Author:	Cai, Nan\|Zhou, Wei\|Ye, Lan-Lan\|Chen, Jun\|Liang, Qiu-Ni\|Chang, Gang\|Chen, Jia-Jie
PMID:	28861175

521.
Journal:	Apoptosis. 2017 Nov;22(11):1404-1418.
Title:	20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells.
Author:	Ai, Hui-Han\|Zhou, Zi-Long\|Sun, Lu-Guo\|Yang, Mei-Ting\|Li, Wei\|Yu, Chun-Lei\|Song, Zhen-Bo\|Huang, Yan-Xin\|Wu, Yin\|Liu, Lei\|Yang, Xiao-Guang\|Zhao, Yu-Qing\|Bao, Yong-Li\|Li, Yu-Xin
PMID:	28864870

522.
Journal:	Int J Biochem Cell Biol. 2017 Oct;91(Pt A):53-59.
Title:	miR-107-mediated decrease of HMGCS2 indicates poor outcomes and promotes cell migration in hepatocellular carcinoma.
Author:	Su, Shu-Guang\|Yang, Mei\|Zhang, Mei-Fang\|Peng, Quan-Zhou\|Li, Ming-Yue\|Liu, Li-Ping\|Bao, Shi-Yun
PMID:	28867541

523.
Journal:	Sci Rep. 2017 Sep 5;7(1):10499.
Title:	Cell Spheroids with Enhanced Aggressiveness to Mimic Human Liver Cancer In Vitro and In Vivo.
Author:	Jung, Hong-Ryul\|Kang, Hyun Mi\|Ryu, Jea-Woon\|Kim, Dae-Soo\|Noh, Kyung Hee\|Kim, Eun-Su\|Lee, Ho-Joon\|Chung, Kyung-Sook\|Cho, Hyun-Soo\|Kim, Nam-Soon\|Im, Dong-Soo\|Lim, Jung Hwa\|Jung, Cho-Rok
PMID:	28874716

524.
Journal:	Mol Med Rep. 2017 Nov;16(5):6299-6305.
Title:	Antitumor activity of 2[(2E)3,7dimethyl2,6octadienyl]6methyl2,5cyclohexadiene1,4dione isolated from the aerial part of Atractylodes macrocephala in hepatocellular carcinoma.
Author:	Li, Lei\|Zhao, Rui\|Li, Ying\|Wang, Wen-Hui
PMID:	28901513

525.
Journal:	Int J Oncol. 2017 Oct;51(4):1291-1299.
Title:	Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo.
Author:	Liu, Xiaoni\|Xu, Jianji\|Wang, Shuang\|Yu, Xiaoxiao\|Kou, Boxin\|Chai, Mengyin\|Zang, Yunjin\|Chen, Dexi
PMID:	28902369

526.
Journal:	Oncotarget. 2017 Jul 5;8(33):55084-55093.
Title:	Tumor-specific hepatic stellate cells (tHSCs) induces DIgR2 expression in dendritic cells to inhibit T cells.
Author:	Xia, Yun-Hong\|Lu, Zhen\|Zhao, Min\|Dai, Wen-Ting\|Ding, Lu\|Hu, Li-Xia\|Jiang, Guo-Lin
PMID:	28903404

527.
Journal:	Cancer Res. 2017 Nov 1;77(21):5831-5845.
Title:	ANGPTL1 Interacts with Integrin alpha1beta1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Author:	Yan, Qian\|Jiang, Lingxi\|Liu, Ming\|Yu, Dandan\|Zhang, Yu\|Li, Yan\|Fang, Shuo\|Li, Yan\|Zhu, Ying-Hui\|Yuan, Yun-Fei\|Guan, Xin-Yuan
PMID:	28904065

528.
Journal:	Sci Rep. 2017 Sep 14;7(1):11563.
Title:	Inhibition of fucosylation by 2-fluorofucose suppresses human liver cancer HepG2 cell proliferation and migration as well as tumor formation.
Author:	Zhou, Ying\|Fukuda, Tomohiko\|Hang, Qinglei\|Hou, Sicong\|Isaji, Tomoya\|Kameyama, Akihiko\|Gu, Jianguo
PMID:	28912543

529.
Journal:	Oncol Lett. 2017 Sep;14(3):2831-2837.
Title:	Long non-coding RNA Igf2as controls hepatocellular carcinoma progression through the ERK/MAPK signaling pathway.
Author:	Bao, Han\|Guo, Chun-Guang\|Qiu, Peng-Cheng\|Zhang, Xin-Lei\|Dong, Qi\|Wang, Yu-Kun
PMID:	28928822

530.
Journal:	Sci Rep. 2017 Sep 28;7(1):12362.
Title:	Up-regulation of chemokine receptor CCR4 is associated with Human Hepatocellular Carcinoma malignant behavior.
Author:	Cheng, Xi\|Wu, Huo\|Jin, Zhi-Jian\|Ma, Ding\|Yuen, Stanley\|Jing, Xiao-Qian\|Shi, Min-Min\|Shen, Bai-Yong\|Peng, Cheng-Hong\|Zhao, Ren\|Qiu, Wei-Hua
PMID:	28959024

531.
Journal:	Cancer Lett. 2017 Dec 28;411:117-129.
Title:	BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma.
Author:	Ma, Junli\|Zeng, Shan\|Zhang, Yan\|Deng, Ganlu\|Qu, Yanling\|Guo, Cao\|Yin, Ling\|Han, Ying\|Cai, Changjing\|Li, Yiyi\|Wang, Guqi\|Bonkovsky, Herbert L\|Shen, Hong
PMID:	28987388

532.
Journal:	Sci Rep. 2017 Oct 9;7(1):12803.
Title:	N-terminal gelsolin fragment potentiates TRAIL mediated death in resistant hepatoma cells.
Author:	Meyer, Keith\|Kwon, Young-Chan\|Ray, Ratna B\|Ray, Ranjit
PMID:	28993697

533.
Journal:	Cancer Med. 2017 Dec;6(12):2787-2795.
Title:	Phosphorylated ERK is a potential prognostic biomarker for Sorafenib response in hepatocellular carcinoma.
Author:	Liang, Yuelong\|Chen, Jiang\|Yu, Qingsong\|Ji, Tong\|Zhang, Bin\|Xu, Junjie\|Dai, Yi\|Xie, Yangyang\|Lin, Hui\|Liang, Xiao\|Cai, Xiujun
PMID:	29030911

534.
Journal:	Sci Rep. 2017 Oct 16;7(1):13201.
Title:	Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas.
Author:	Lee, Hyun Min\|Joh, Jae Won\|Seo, Se-Ri\|Kim, Won-Tae\|Kim, Min Kyu\|Choi, Hong Seo\|Kim, So Young\|Jang, Young-Joo\|Sinn, Dong Hyun\|Choi, Gyu Seong\|Kim, Jong Man\|Kwon, Choon Hyuck David\|Chang, Hee Jin\|Kim, Dae Shick\|Ryu, Chun Jeih
PMID:	29038587

535.
Journal:	Int J Oncol. 2017 Nov;51(5):1449-1459.
Title:	Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
Author:	Liao, Bo\|Zhou, Honghao\|Liang, Huifang\|Li, Changhai
PMID:	29048612

536.
Journal:	Ann Clin Lab Sci. 2017 Sep;47(5):572-580.
Title:	Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line.
Author:	Chowdhury, Parimal
PMID:	29066484

537.
Journal:	Nutr Cancer. 2017 Nov-Dec;69(8):1272-1280.
Title:	Silibinin Reduces the Impact of Obesity on Invasive Liver Cancer.
Author:	Miethe, C\|Nix, H\|Martin, R\|Hernandez, A R\|Price, R S
PMID:	29068700

538.
Journal:	Clin Epigenetics. 2017 Oct 23;9:116.
Title:	Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Author:	Guo, Yulin\|Peng, Yaojun\|Gao, Dan\|Zhang, Meiying\|Yang, Weili\|Linghu, Enqiang\|Herman, James G\|Fuks, Francois\|Dong, Guanglong\|Guo, Mingzhou
PMID:	29075359

539.
Journal:	World J Gastroenterol. 2017 Sep 28;23(36):6639-6649.
Title:	Attenuation of MET-mediated migration and invasion in hepatocellular carcinoma cells by SOCS1.
Author:	Gui, Yirui\|Khan, Md Gulam Musawwir\|Bobbala, Diwakar\|Dubois, Claire\|Ramanathan, Sheela\|Saucier, Caroline\|Ilangumaran, Subburaj
PMID:	29085209

540.
Journal:	Oncotarget. 2017 Jul 17;8(44):76223-76230.
Title:	Overexpression of SIRT6 attenuates the tumorigenicity of hepatocellular carcinoma cells.
Author:	Wang, Yadong\|Pan, Teng\|Wang, Haiyu\|Li, Li\|Li, Jiangmin\|Zhang, Ding\|Yang, Haiyan
PMID:	29100306

541.
Journal:	Oncotarget. 2017 Aug 18;8(44):77096-77109.
Title:	Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish.
Author:	Yan, Chuan\|Yang, Qiqi\|Shen, Han-Ming\|Spitsbergen, Jan M\|Gong, Zhiyuan
PMID:	29100373

542.
Journal:	Oncotarget. 2017 Sep 15;8(44):77915-77927.
Title:	Effect of TALEN-mediated IL-6 knockout on cell proliferation, apoptosis, invasion and anti-cancer therapy in hepatocellular carcinoma (HCC-LM3) cells.
Author:	Zhuang, Peng-Yuan\|Zhang, Ke-Wei\|Wang, Jian-Dong\|Zhou, Xue-Ping\|Liu, Ying-Bin\|Quan, Zhi-Wei\|Shen, Jun
PMID:	29100435

543.
Journal:	Oncotarget. 2017 Jul 6;8(46):80429-80442.
Title:	Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10.
Author:	Cheng, Wei\|Huang, Po-Chun\|Chao, Hsiao-Mei\|Jeng, Yung-Ming\|Hsu, Hey-Chi\|Pan, Hung-Wei\|Hwu, Wuh-Liang\|Lee, Yu-May
PMID:	29113314

544.
Journal:	Nat Med. 2017 Dec;23(12):1424-1435.
Title:	Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Author:	Broutier, Laura\|Mastrogiovanni, Gianmarco\|Verstegen, Monique Ma\|Francies, Hayley E\|Gavarro, Lena Morrill\|Bradshaw, Charles R\|Allen, George E\|Arnes-Benito, Robert\|Sidorova, Olga\|Gaspersz, Marcia P\|Georgakopoulos, Nikitas\|Koo, Bon-Kyoung\|Dietmann, Sabine\|Da
PMID:	29131160

545.
Journal:	Oncotarget. 2016 Oct 18;8(48):83469-83479.
Title:	AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-kappaB signaling pathways.
Author:	Chow, Raymond Kwok Kei\|Tsz-Kwan Sin, Sarah\|Liu, Ming\|Li, Yan\|Man Chan, Tim Hon\|Song, Yangyang\|Chen, Leilei\|Lai-Wan Kwong, Dora\|Guan, Xin-Yuan
PMID:	29137357

546.
Journal:	Oncotarget. 2017 Sep 23;8(50):87737-87749.
Title:	microRNA-526b servers as a prognostic factor and exhibits tumor suppressive property by targeting Sirtuin 7 in hepatocellular carcinoma.
Author:	Liu, Xin\|Yang, Liu\|Tu, Jianfeng\|Cai, Wenwei\|Zhang, Meiqi\|Shou, Zhangxuan\|Yao, Yingmin\|Xu, Qiuran
PMID:	29152116

547.
Journal:	Oncotarget. 2017 May 9;8(49):84958-84973.
Title:	Interaction of microRNA-21/145 and Smad3 domain-specific phosphorylation in hepatocellular carcinoma.
Author:	Wang, Ji Yu\|Fang, Meng\|Boye, Alex\|Wu, Chao\|Wu, Jia Jun\|Ma, Ying\|Hou, Shu\|Kan, Yue\|Yang, Yan
PMID:	29156696

548.
Journal:	Sci Rep. 2017 Dec 20;7(1):17943.
Title:	Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.
Author:	Kuppusamy, Panjamurthy\|Nagalingam, Arumugam\|Muniraj, Nethaji\|Saxena, Neeraj K\|Sharma, Dipali
PMID:	29263422

549.
Journal:	Oncoimmunology. 2017 Oct 26;7(1):e1368603.
Title:	The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.
Author:	Lenk, Lennart\|Pein, Maren\|Will, Olga\|Gomez, Beatriz\|Viol, Fabrice\|Hauser, Charlotte\|Egberts, Jan-Hendrik\|Gundlach, Jan-Paul\|Helm, Ole\|Tiwari, Sanjay\|Weiskirchen, Ralf\|Rose-John, Stefan\|Rocken, Christoph\|Mikulits, Wolfgang\|Wenzel, Patrick\|Schneider, Gunter
PMID:	29296518

550.
Journal:	J BUON. 2017 Nov-Dec;22(6):1517-1524.
Title:	Genetically engineered bone marrow-derived mesenchymal stem cells co-expressing IFN-gamma and IL-10 inhibit hepatocellular carcinoma by modulating MAPK pathway.
Author:	Wang, Hao\|Wang, Jun\|Shi, Xiaolei\|Ding, Yitao
PMID:	29332347

551.
Journal:	ACS Omega. 2017 Apr 30;2(4):1489-1504.
Title:	Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells.
Author:	Fageria, Leena\|Pareek, Vikram\|Dilip, R Venkataramana\|Bhargava, Arpit\|Pasha, Sheik Saleem\|Laskar, Inamur Rahaman\|Saini, Heena\|Dash, Subhra\|Chowdhury, Rajdeep\|Panwar, Jitendra
PMID:	30023637

552.
Journal:	Eur J Nutr. 2018 Apr;57(3):1215-1224.
Title:	Attenuation of liver cancer development by oral glycerol supplementation in the rat.
Author:	Capiglioni, Alejo M\|Lorenzetti, Florencia\|Quiroga, Ariel D\|Parody, Juan P\|Ronco, Maria T\|Pisani, Gerardo B\|Carrillo, Maria C\|Ceballos, Maria P\|Alvarez, Maria de Lujan
PMID:	28255652

553.
Journal:	Int J Hyperthermia. 2018 Sep;34(6):812-823.
Title:	Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma.
Author:	Thompson, Scott M\|Jondal, Danielle E\|Butters, Kim A\|Knudsen, Bruce E\|Anderson, Jill L\|Stokes, Matthew P\|Jia, Xiaoying\|Grande, Joseph P\|Roberts, Lewis R\|Callstrom, Matthew R\|Woodrum, David A
PMID:	28954551

554.
Journal:	Cell Biol Int. 2018 Feb;42(2):194-204.
Title:	OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.
Author:	Ren, Jie\|Liu, Yu\|Li, Lixia\|Zhao, Yuexin\|Li, Zhongyu\|Wu, Chao\|Chen, Lin\|Hu, Kun
PMID:	29052919

555.
Journal:	Int J Oncol. 2018 Jan;52(1):189-200.
Title:	Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins.
Author:	De Araujo, Raimundo F Jr\|Pessoa, Jonas B\|Cruz, Luis J\|Chan, Alan B\|De Castro Miguel, Emilio\|Cavalcante, Romulo S\|Brito, Gerly Anne C\|Silva, Heloiza Fernada O\|Gasparotto, Luiz H S\|Guedes, Paulo M M\|Araujo, Aurigena A
PMID:	29115423

556.
Journal:	Life Sci. 2018 Jan 1;192:286-292.
Title:	Dihydroartemisinin induced caspase-dependent apoptosis through inhibiting the specificity protein 1 pathway in hepatocellular carcinoma SK-Hep-1 cells.
Author:	Im, Eunji\|Yeo, Changhwan\|Lee, Hyo-Jeong\|Lee, Eun-Ok
PMID:	29128513

557.
Journal:	Biomed Pharmacother. 2018 Jan;97:1282-1288.
Title:	Synergistic anticancer activity of 20(S)-Ginsenoside Rg3 and Sorafenib in hepatocellular carcinoma by modulating PTEN/Akt signaling pathway.
Author:	Lu, Mingxia\|Fei, Zhenghua\|Zhang, Ganlu
PMID:	29156516

558.
Journal:	Environ Toxicol. 2018 Mar;33(3):261-268.
Title:	Cantharidic acid induces apoptosis through the p38 MAPK signaling pathway in human hepatocellular carcinoma.
Author:	Feng, I-Che\|Hsieh, Ming-Ju\|Chen, Pei-Ni\|Hsieh, Yi-Hsien\|Ho, Hsin-Yu\|Yang, Shun-Fa\|Yeh, Chao-Bin
PMID:	29159945

559.
Journal:	Biochem Biophys Res Commun. 2018 Jan 1;495(1):1136-1143.
Title:	Downregulation of Nedd4L predicts poor prognosis, promotes tumor growth and inhibits MAPK/ERK signal pathway in hepatocellular carcinoma.
Author:	Zhao, Fengbo\|Gong, Xiu\|Liu, Aifen\|Lv, Xiufang\|Hu, Baoying\|Zhang, Haijian
PMID:	29175326

560.
Journal:	Acta Pharmacol Sin. 2018 Mar;39(3):438-448.
Title:	Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling.
Author:	Zhang, Su-Shan\|Ni, Yu-Hao\|Zhao, Chen-Ru\|Qiao, Zhen\|Yu, Hong-Xia\|Wang, Lu-Yao\|Sun, Jin-Yan\|Du, Chen\|Zhang, Jia-Hao\|Dong, Li-Ying\|Wang, KeWei\|Gao, Jian-Jun
PMID:	29188798

561.
Journal:	J Biomater Appl. 2018 Feb;32(7):945-956.
Title:	Localized delivery of chemokine for in vitro manipulation of hepatocellular carcinoma cell behaviors during the epithelial-mesenchymal transition.
Author:	Liu, Xi-Qiu\|Tang, Rui-Zhi
PMID:	29199892

562.
Journal:	Int J Cancer. 2018 Apr 15;142(8):1712-1722.
Title:	Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.
Author:	Kaji, Kosuke\|Nishimura, Norihisa\|Seki, Kenichiro\|Sato, Shinya\|Saikawa, Soichiro\|Nakanishi, Keisuke\|Furukawa, Masanori\|Kawaratani, Hideto\|Kitade, Mitsuteru\|Moriya, Kei\|Namisaki, Tadashi\|Yoshiji, Hitoshi
PMID:	29205334

563.
Journal:	Oncol Rep. 2018 Feb;39(2):843-850.
Title:	Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib.
Author:	Yokoi, Kenta\|Kobayashi, Akira\|Motoyama, Hiroaki\|Kitazawa, Masato\|Shimizu, Akira\|Notake, Tsuyoshi\|Yokoyama, Takahide\|Matsumura, Tomio\|Takeoka, Michiko\|Miyagawa, Shin-Ichi
PMID:	29251327

564.
Journal:	Int J Biochem Cell Biol. 2018 Mar;96:9-19.
Title:	Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells.
Author:	Liu, Chang\|Shen, Gui-Nan\|Luo, Ying-Hua\|Piao, Xian-Ji\|Jiang, Xue-Yuan\|Meng, Ling-Qi\|Wang, Yue\|Zhang, Yi\|Wang, Jia-Ru\|Wang, Hao\|Xu, Wan-Ting\|Li, Jin-Qian\|Liu, Yang\|Wu, Yi-Qin\|Sun, Hu-Nan\|Han, Ying-Hao\|Jin, Mei-Hua\|Cui, Yu-Dong\|Fang, Nan-Zhu\|Jin, Cheng-Hao
PMID:	29326072

565.
Journal:	Cancer Res. 2018 May 1;78(9):2219-2232.
Title:	Demethylation-Induced Overexpression of Shc3 Drives c-Raf-Independent Activation of MEK/ERK in HCC.
Author:	Liu, Yun\|Zhang, Xinran\|Yang, Baicai\|Zhuang, Hao\|Guo, Hua\|Wei, Wen\|Li, Yuan\|Chen, Ruibing\|Li, Yongmei\|Zhang, Ning
PMID:	29330146

566.
Journal:	J Exp Clin Cancer Res. 2018 Jan 22;37(1):10.
Title:	MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence.
Author:	Liu, Mingyu\|Hu, Qiaoting\|Tu, Mengxian\|Wang, Xinyi\|Yang, Zike\|Yang, Guoxiong\|Luo, Rongcheng
PMID:	29357919

567.
Journal:	Cancer Sci. 2018 Apr;109(4):1088-1100.
Title:	Tunicamycin inhibits cell proliferation and migration in hepatocellular carcinoma through suppression of CD44s and the ERK1/2 pathway.
Author:	Hou, Helei\|Ge, Chao\|Sun, Hefen\|Li, Hong\|Li, Jinjun\|Tian, Hua
PMID:	29377347

568.
Journal:	World J Hepatol. 2018 Jan 27;10(1):155-165.
Title:	Epigenetic basis of hepatocellular carcinoma: A network-based integrative meta-analysis.
Author:	Bhat, Venkat\|Srinathan, Sujitha\|Pasini, Elisa\|Angeli, Marc\|Chen, Emily\|Baciu, Cristina\|Bhat, Mamatha
PMID:	29399289

569.
Journal:	Biochem Biophys Res Commun. 2018 Feb 26;497(1):32-38.
Title:	GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.
Author:	Schmid, Christian David\|Schledzewski, Kai\|Mogler, Carolin\|Waldburger, Nina\|Kalna, Viktoria\|Marx, Alexander\|Randi, Anna Maria\|Geraud, Cyrill\|Goerdt, Sergij\|Koch, Philipp-Sebastian
PMID:	29408502

570.
Journal:	Gene Expr. 2018 May 18;18(2):135-147.
Title:	The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, beta-Catenin-Mutated Mouse Model.
Author:	Zhan, Na\|Michael, Adeola Adebayo\|Wu, Kaiyuan\|Zeng, Gang\|Bell, Aaron\|Tao, Junyan\|Monga, Satdarshan P
PMID:	29409568

571.
Journal:	Am J Cancer Res. 2018 Jan 1;8(1):154-164. eCollection 2018.
Title:	Isocorydine suppresses doxorubicin-induced epithelial-mesenchymal transition via inhibition of ERK signaling pathways in hepatocellular carcinoma.
Author:	Pan, Jie-Xue\|Chen, Gang\|Li, Jun-Jian\|Zhu, Qian-Dong\|Li, Jing-Jie\|Chen, Zong-Jing\|Yu, Zheng-Ping\|Ye, Long-Yun
PMID:	29416928

572.
Journal:	Oncotarget. 2017 Dec 11;9(3):3605-3618.
Title:	Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option.
Author:	Dietrich, Peter\|Freese, Kim\|Mahli, Abdo\|Thasler, Wolfgang Erwin\|Hellerbrand, Claus\|Bosserhoff, Anja Katrin
PMID:	29423069

573.
Journal:	Int J Mol Med. 2018 May;41(5):2893-2900.
Title:	Downregulation of secreted clusterin potentiates the lethality of sorafenib in hepatocellular carcinoma in association with the inhibition of ERK1/2 signals.
Author:	Zhong, Jingtao\|Yu, Xiaoming\|Dong, Xiaofeng\|Lu, Hong\|Zhou, Wuyuan\|Li, Lei\|Li, Zhongchao\|Sun, Pengfei\|Shi, Xuetao
PMID:	29436591

574.
Journal:	Cancer Med. 2018 Mar;7(3):869-882.
Title:	PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma.
Author:	Jiang, Hai\|Zhu, Yue\|Zhou, Zhenyu\|Xu, Junyang\|Jin, Shaowen\|Xu, Kang\|Zhang, Heyun\|Sun, Qing\|Wang, Jie\|Xu, Junyao
PMID:	29441724

575.
Journal:	Cell Death Differ. 2018 Sep;25(9):1612-1624.
Title:	Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma.
Author:	Li, Jiao\|Pu, Wenchen\|Sun, Hui-Lung\|Zhou, Jian-Kang\|Fan, Xin\|Zheng, Yuanyuan\|He, Juan\|Liu, Xuesha\|Xia, Zhichu\|Liu, Lunxu\|Wei, Yu-Quan\|Peng, Yong
PMID:	29445125

576.
Journal:	Theranostics. 2018 Jan 1;8(4):894-905.
Title:	Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development.
Author:	Sung, Yun-Chieh\|Liu, Ya-Chi\|Chao, Po-Han\|Chang, Chih-Chun\|Jin, Pei-Ru\|Lin, Ts-Ting\|Lin, Ja-An\|Cheng, Hui-Teng\|Wang, Jane\|Lai, Charles P\|Chen, Ling-Hsuan\|Wu, Anthony Y\|Ho, Ting-Lun\|Chiang, Tsaiyu\|Gao, Dong-Yu\|Duda, Dan G\|Chen, Yunching
PMID:	29463989

577.
Journal:	Steroids. 2018 Jun;134:78-87.
Title:	The ER-alpha36/EGFR signaling loop promotes growth of hepatocellular carcinoma cells.
Author:	You, Hui\|Meng, Kun\|Wang, Zhao-Yi
PMID:	29481815

578.
Journal:	Phytomedicine. 2018 Feb 1;40:98-105.
Title:	Early LC3 lipidation induced by d-limonene does not rely on mTOR inhibition, ERK activation and ROS production and it is associated with reduced clonogenic capacity of SH-SY5Y neuroblastoma cells.
Author:	Berliocchi, Laura\|Chiappini, Carlotta\|Adornetto, Annagrazia\|Gentile, Debora\|Cerri, Silvia\|Russo, Rossella\|Bagetta, Giacinto\|Corasaniti, Maria Tiziana
PMID:	29496180

579.
Journal:	J Hepatol. 2018 Jul;69(1):79-88.
Title:	Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic beta-Catenin, PIK3CA and MET.
Author:	Liu, Jacey J\|Li, Yanjie\|Chen, Wendy S\|Liang, Yan\|Wang, Gaowei\|Zong, Min\|Kaneko, Kota\|Xu, Ruiyun\|Karin, Michael\|Feng, Gen-Sheng
PMID:	29505847

580.
Journal:	J Exp Clin Cancer Res. 2018 Mar 5;37(1):45.
Title:	Downregulation of castor zinc finger 1 predicts poor prognosis and facilitates hepatocellular carcinoma progression via MAPK/ERK signaling.
Author:	Wang, Ji-Long\|Yang, Meng-Yuan\|Xiao, Shuai\|Sun, Bo\|Li, Yi-Ming\|Yang, Lian-Yue
PMID:	29506567

581.
Journal:	Life Sci. 2018 Apr 15;199:48-59.
Title:	Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
Author:	Rodenak-Kladniew, Boris\|Castro, Agustina\|Starkel, Peter\|De Saeger, Christine\|Garcia de Bravo, Margarita\|Crespo, Rosana
PMID:	29510199

582.
Journal:	World J Gastroenterol. 2018 Mar 14;24(10):1120-1133.
Title:	Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma.
Author:	Sun, Liang\|Li, Pi-Bao\|Yao, Yan-Fen\|Xiu, Ai-Yuan\|Peng, Zhi\|Bai, Yu-Huan\|Gao, Yan-Jing
PMID:	29563756

583.
Journal:	Anticancer Drugs. 2018 Jul;29(6):513-519.
Title:	Inhibition of anaplastic lymphoma kinase promotes apoptosis and suppresses proliferation in human hepatocellular carcinoma.
Author:	Yu, Zhen\|Zhao, Ronglei
PMID:	29570100

584.
Journal:	Med Sci Monit. 2018 Mar 26;24:1759-1767.
Title:	MAP Kinase-Interacting Kinase 1 Promotes Proliferation and Invasion of Hepatocellular Carcinoma and Is an Unfavorable Prognostic Biomarker.
Author:	Wang, Xujing\|Wang, Yongkun\|Zhang, Qiqi\|Zhuang, Huiren\|Chen, Bo
PMID:	29576605

585.
Journal:	Anticancer Res. 2018 Apr;38(4):2119-2125.
Title:	Amentoflavone Enhances the Therapeutic Efficacy of Sorafenib by Inhibiting Anti-apoptotic Potential and Potentiating Apoptosis in Hepatocellular Carcinoma In Vivo.
Author:	Tsai, Jai-Jen\|Hsu, Fei-Ting\|Pan, Po-Jung\|Chen, Chia-Wen\|Kuo, Yu-Cheng
PMID:	29599330

586.
Journal:	Biomed Pharmacother. 2018 May;101:910-919.
Title:	Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway.
Author:	Fang, Yu\|Liu, Guoxing\|Xie, Chengzhi\|Qian, Ke\|Lei, Xiaohua\|Liu, Qiang\|Liu, Gao\|Cao, Zhenyu\|Fu, Jie\|Du, Huihui\|Liu, Sushun\|Huang, Shengfu\|Hu, Jixiong\|Xu, Xundi
PMID:	29635900

587.
Journal:	Biomed Pharmacother. 2018 Jul;103:272-283.
Title:	Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARgamma.
Author:	Han, Mei\|Gao, Hui\|Ju, Ping\|Gao, Ming-Quan\|Yuan, Yin-Ping\|Chen, Xue-Hong\|Liu, Kai-Li\|Han, Yan-Tao\|Han, Zhi-Wu
PMID:	29656183

588.
Journal:	Cell Death Dis. 2018 May 1;9(5):482.
Title:	The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Author:	Li, Wenjuan\|Cui, Kaisa\|Prochownik, Edward V\|Li, Youjun
PMID:	29706623

589.
Journal:	Genomics Proteomics Bioinformatics. 2018 Apr;16(2):120-126.
Title:	The Role of Exportin-5 in MicroRNA Biogenesis and Cancer.
Author:	Wu, Ke\|He, Juan\|Pu, Wenchen\|Peng, Yong
PMID:	29723684

590.
Journal:	Cell Death Dis. 2018 May 1;9(5):513.
Title:	HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway.
Author:	Chen, Lu\|Guo, Piao\|He, Yuchao\|Chen, Ziye\|Chen, Liwei\|Luo, Yi\|Qi, Lisha\|Liu, Yuanyuan\|Wu, Qiang\|Cui, Yunlong\|Fang, Feng\|Zhang, Xiaofang\|Song, Tianqiang\|Guo, Hua
PMID:	29725020

591.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2018 Apr 20;38(4):477-482.
Title:	[Glycyrrhetinic acid selectively inhibits proliferation of hepatocellular carcinoma cells in vitro].
Author:	Zhang, Yun-Qi\|Cai, Yun\|Liu, Yuan\|Zhao, Bo-Xin\|Li, Guo-Feng
PMID:	29735451

592.
Journal:	Cell Death Dis. 2018 May 1;9(5):549.
Title:	MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1alpha-mediated Warburg effect.
Author:	Chen, Zhiqiang\|Zuo, Xueliang\|Zhang, Yao\|Han, Guoyong\|Zhang, Long\|Wu, Jindao\|Wang, Xuehao
PMID:	29748591

593.
Journal:	Mol Carcinog. 2018 Sep;57(9):1201-1212.
Title:	A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.
Author:	Wang, Ruizhi\|Jin, Yi\|Yao, Xue-Hua\|Fan, Wenzhe\|Zhang, Jiang\|Cao, Yihai\|Li, Jiaping
PMID:	29749642

594.
Journal:	Cell Physiol Biochem. 2018;47(1):39-53.
Title:	Serum from Chronic Hepatitis B Patients Promotes Growth and Proliferation via the IGF-II/IGF-IR/MEK/ERK Signaling Pathway in Hepatocellular Carcinoma Cells.
Author:	Ji, Yuanyuan\|Wang, Zhidong\|Chen, Haiyan\|Zhang, Lei\|Zhuo, Fei\|Yang, Qingqing
PMID:	29763915

595.
Journal:	Oncotarget. 2018 Apr 20;9(30):21429-21443.
Title:	MTBP inhibits the Erk1/2-Elk-1 signaling in hepatocellular carcinoma.
Author:	Ranjan, Atul\|Iyer, Swathi V\|Ward, Christopher\|Link, Tim\|Diaz, Francisco J\|Dhar, Animesh\|Tawfik, Ossama W\|Weinman, Steven A\|Azuma, Yoshiaki\|Izumi, Tadahide\|Iwakuma, Tomoo
PMID:	29765550

596.
Journal:	Eur J Pharmacol. 2018 Aug 5;832:39-49.
Title:	Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT.
Author:	Mao, Jie\|Yang, Hongbao\|Cui, Tingting\|Pan, Pan\|Kabir, Nadia\|Chen, Duo\|Ma, Jinyan\|Chen, Xingyi\|Chen, Yijun\|Yang, Yong
PMID:	29782854

597.
Journal:	Biosci Trends. 2018 Jul 17;12(3):291-297.
Title:	Cinobufacini inhibits epithelial-mesenchymal transition of human hepatocellular carcinoma cells through c-Met/ERK signaling pathway.
Author:	Qi, Fanghua\|Wang, Jinjing\|Zhao, Lin\|Cai, Pingping\|Tang, Wei\|Wang, Zhixue
PMID:	29794405

598.
Journal:	Biochem Biophys Res Commun. 2018 Jul 12;502(2):194-201.
Title:	Effect of long non-coding RNA H19 on oxidative stress and chemotherapy resistance of CD133+ cancer stem cells via the MAPK/ERK signaling pathway in hepatocellular carcinoma.
Author:	Ding, Kai\|Liao, Yannian\|Gong, Dinghao\|Zhao, Xin\|Ji, Wu
PMID:	29800569

599.
Journal:	Bioorg Chem. 2018 Sep;79:355-362.
Title:	Pyran-2-one derivatives from Croton crassifolius as potent apoptosis inducers in HepG2 cells via p53-mediated Ras/Raf/ERK pathway.
Author:	Tian, Jin-Long\|Yao, Guo-Dong\|Zhang, Ying-Ying\|Lin, Bin\|Zhang, Yan\|Li, Ling-Zhi\|Huang, Xiao-Xiao\|Song, Shao-Jiang
PMID:	29852310

600.
Journal:	J Cancer Res Clin Oncol. 2018 Aug;144(8):1487-1501.
Title:	Downregulation of Raf-1 kinase inhibitory protein as a sorafenib resistance mechanism in hepatocellular carcinoma cell lines.
Author:	Kim, Jin Sun\|Choi, Gwang Hyeon\|Jung, Yusun\|Kim, Kang Mo\|Jang, Se-Jin\|Yu, Eun Sil\|Lee, Han Chu
PMID:	29858683

601.
Journal:	Oxid Med Cell Longev. 2018 May 10;2018:5287971.
Title:	Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition.
Author:	He, Qiang\|Li, Hui\|Meng, Fanzhi\|Sun, Xiangjun\|Feng, Xu\|Chen, Jiang\|Li, Libo\|Liu, Jinghua
PMID:	29861830

602.
Journal:	J Exp Clin Cancer Res. 2018 Jun 4;37(1):113.
Title:	Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1alpha/VEGFA signalling in hepatocellular carcinoma.
Author:	Lin, Jinduan\|Cao, Shunwang\|Wang, Yu\|Hu, Yanwei\|Liu, Hongwei\|Li, Jiehua\|Chen, Jing\|Li, Pan\|Liu, Jumei\|Wang, Qian\|Zheng, Lei
PMID:	29866133

603.
Journal:	Mar Drugs. 2018 Jun 7;16(6). pii: md16060200.
Title:	Tachypleus tridentatus Lectin Enhances Oncolytic Vaccinia Virus Replication to Suppress In Vivo Hepatocellular Carcinoma Growth.
Author:	Li, Gongchu\|Cheng, Jianhong\|Mei, Shengsheng\|Wu, Tao\|Ye, Ting
PMID:	29880736

604.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Jun;22(11):3386-3393.
Title:	Correlation between HSD17B4 expression in rat liver cancer tissues and inflammation or proliferation.
Author:	Pan, L-C\|Xiao, H-Y\|Yin, W-J\|Lin, Z
PMID:	29917219

605.
Journal:	J Exp Clin Cancer Res. 2018 Jun 28;37(1):128.
Title:	Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway.
Author:	Chen, Xueran\|Zhang, Shangrong\|Wang, Zhen\|Wang, Fengsong\|Cao, Xinwang\|Wu, Quan\|Zhao, Chenggang\|Ma, Huihui\|Ye, Fang\|Wang, Hongzhi\|Fang, Zhiyou
PMID:	29954442

606.
Journal:	Environ Toxicol. 2018 Sep;33(9):946-954.
Title:	Coronarin D induces apoptotic cell death through the JNK pathway in human hepatocellular carcinoma.
Author:	Lin, Hui-Wen\|Hsieh, Ming-Ju\|Yeh, Chao-Bin\|Hsueh, Kuan-Chun\|Hsieh, Yi-Hsien\|Yang, Shun-Fa
PMID:	29968959

607.
Journal:	Integr Cancer Ther. 2018 Jul 1:1534735418785999.
Title:	Antitumor Efficacy of Huqizhengxiao (HQZX) Decoction Based on Inhibition of Telomerase Activity in Nude Mice of Hepatocarcinoma Xenograft.
Author:	Yu, XiaoXiao\|Lin, Xue-Jun\|Wang, Shuang\|Liu, XiuHong\|Li, WeiHua\|Kou, Bu-Xin\|Chai, MengYin\|Chen, DeXi\|Liu, XiaoNi\|Wang, XiaoJun
PMID:	29978739

608.
Journal:	Biochem Pharmacol. 2018 Sep;155:305-315.
Title:	HCV-induced EGFR-ERK signaling promotes a pro-inflammatory and pro-angiogenic signature contributing to liver cancer pathogenesis.
Author:	Benkheil, Mohammed\|Paeshuyse, Jan\|Neyts, Johan\|Van Haele, Matthias\|Roskams, Tania\|Liekens, Sandra
PMID:	30012461

609.
Journal:	Sci Rep. 2018 Jul 19;8(1):10923.
Title:	Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells.
Author:	Wang, Jing\|Sun, Peng\|Chen, Yijun\|Yao, Hequan\|Wang, Shuzhen
PMID:	30026540

610.
Journal:	Hepatology. 2018 Jul 20.
Title:	A CCDC50 splice variant is modulated by SRSF3 and promotes hepatocellular carcinoma via the Ras signaling pathway.
Author:	Hong, Wang\|Zhang, Chris Zhiyi\|Lu, Shi-Xun\|Zhang, Mei-Fang\|Liu, Li-Li\|Luo, Rong-Zhen\|Yang, Xia\|Wang, Chun-Hua\|Chen, Shi-Lu\|He, Yang-Fan\|Xie, Dan\|Xu, Rui-Hua\|Yun, Jing-Ping
PMID:	30028541

611.
Journal:	J Hepatol. 2018 Jul 18. pii: S0168-8278(18)32184-6.
Title:	Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer.
Author:	Wang, Cun\|Jin, Haojie\|Gao, Dongmei\|Lieftink, Cor\|Evers, Bastiaan\|Jin, Guangzhi\|Xue, Zheng\|Wang, Liqin\|Beijersbergen, Roderick L\|Qin, Wenxin\|Bernards, Rene
PMID:	30030148

612.
Journal:	Transl Gastroenterol Hepatol. 2018 Jun 29;3:36.
Title:	Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma.
Author:	Pascale, Rosa M\|Feo, Claudio F\|Calvisi, Diego F\|Feo, Francesco
PMID:	30050996

613.
Journal:	Int J Mol Med. 2018 Nov;42(5):2551-2559.
Title:	Synergistic effect of ursodeoxycholic acid on the antitumor activity of sorafenib in hepatocellular carcinoma cells via modulation of STAT3 and ERK.
Author:	Lee, Seulki\|Cho, Young Youn\|Cho, Eun Ju\|Yu, Su Jong\|Lee, Jeong-Hoon\|Yoon, Jung-Hwan\|Kim, Yoon Jun
PMID:	30106087

614.
Journal:	Hepatobiliary Pancreat Dis Int. 2018 Aug;17(4):336-344.
Title:	MicroRNA-449a suppresses hepatocellular carcinoma cell growth via G1 phase arrest and the HGF/MET c-Met pathway.
Author:	Cheng, Jun\|Wu, Li-Ming\|Deng, Xue-Song\|Wu, Jian\|Lv, Zhen\|Zhao, Hang-Fen\|Yang, Zhang\|Ni, Yong
PMID:	30108016

615.
Journal:	Biomed Pharmacother. 2018 Nov;107:824-833.
Title:	LncRNA DBH-AS1 facilitates the tumorigenesis of hepatocellular carcinoma by targeting miR-138 via FAK/Src/ERK pathway.
Author:	Bao, Jie\|Chen, Xiaoqi\|Hou, Yuge\|Kang, Gailing\|Li, Qiaoli\|Xu, Yun
PMID:	30142544

616.
Journal:	Biochem Biophys Res Commun. 2018 Sep 18;503(4):3093-3099.
Title:	Anlotinib induces hepatocellular carcinoma apoptosis and inhibits proliferation via Erk and Akt pathway.
Author:	He, Chao\|Wu, Tingting\|Hao, Yongqiang
PMID:	30146257

617.
Journal:	Mol Carcinog. 2018 Sep 4.
Title:	Celecoxib alleviates AKT/c-Met-triggered rapid hepatocarcinogenesis by suppressing a novel COX-2/AKT/FASN cascade.
Author:	Qiu, Zhenpeng\|Zhang, Cong\|Zhou, Junxuan\|Hu, Junjie\|Sheng, Lei\|Li, Xin\|Chen, Liang\|Li, Xiang\|Deng, Xukun\|Zheng, Guohua
PMID:	30182439

618.
Journal:	Toxicol In Vitro. 2018 Sep 6;53:222-232.
Title:	Alpha-mangostin, an active compound in Garcinia mangostana, abrogates anoikis-resistance in human hepatocellular carcinoma cells.
Author:	Wudtiwai, Benjawan\|Pitchakarn, Pornsiri\|Banjerdpongchai, Ratana
PMID:	30195041

619.
Journal:	Lab Invest. 2018 Sep 11. pii: 10.1038/s41374-018-0127-3.
Title:	The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis.
Author:	Wang, Zhuo\|Li, Jia'an\|Xiao, Wen'ang\|Long, Jiafu\|Zhang, Hongmin
PMID:	30206312

620.
Journal:	Oncoimmunology. 2018 Apr 9;7(8):e1450713.
Title:	delta-Catenin peptide vaccines repress hepatocellular carcinoma growth via CD8(+) T cell activation.
Author:	Huang, Fei\|Chen, Junying\|Lan, Ruilong\|Wang, Zeng\|Chen, Ruiqing\|Lin, Jingan\|Zhang, Lurong\|Fu, Lengxi
PMID:	30221043

621.
Journal:	Stem Cells Int. 2018 Aug 27;2018:8058979.
Title:	Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats.
Author:	Alzahrani, Faisal A\|El-Magd, Mohammed A\|Abdelfattah-Hassan, Ahmed\|Saleh, Ayman A\|Saadeldin, Islam M\|El-Shetry, Eman S\|Badawy, Abdelnaser A\|Alkarim, Saleh
PMID:	30224923

622.
Journal:	BMC Cancer. 2018 Sep 18;18(1):901.
Title:	Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment.
Author:	Zhang, Rui\|Ma, Min\|Lin, Xia-Hui\|Liu, Hua-Hua\|Chen, Jie\|Chen, Jun\|Gao, Dong-Mei\|Cui, Jie-Feng\|Ren, Zheng-Gang\|Chen, Rong-Xin
PMID:	30227844

623.
Journal:	J Exp Clin Cancer Res. 2018 Sep 19;37(1):231.
Title:	HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways.
Author:	Li, Qing\|Wang, Cong\|Wang, Yufeng\|Sun, Liankang\|Liu, Zhikui\|Wang, Liang\|Song, Tao\|Yao, Yingmin\|Liu, Qingguang\|Tu, Kangsheng
PMID:	30231922

624.
Journal:	Theranostics. 2018 Sep 9;8(17):4649-4663.
Title:	Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma.
Author:	Liu, Zhikui\|Wang, Yufeng\|Dou, Changwei\|Xu, Meng\|Sun, Liankang\|Wang, Liang\|Yao, Bowen\|Li, Qing\|Yang, Wei\|Tu, Kangsheng\|Liu, Qingguang
PMID:	30279729

625.
Journal:	Clin Exp Med. 2018 Oct 10. pii: 10.1007/s10238-018-0528-z.
Title:	mTOR and ERK regulate VKORC1 expression in both hepatoma cells and hepatocytes which influence blood coagulation.
Author:	Liu, Yaofu\|Li, Huiling\|Dong, Jianyi\|Ma, Lei\|Liao, Aijun\|Rong, Zhuona\|Zhou, Zhi\|Cao, Liang\|Wang, Fujin\|Wang, Jingyu\|Wang, Aiguo
PMID:	30306378

626.
Journal:	J Cell Physiol. 2018 Oct 14.
Title:	LINC00707 promotes hepatocellular carcinoma progression through activating ERK/JNK/AKT pathway signaling pathway.
Author:	Wang, Jianchu\|Luo, Zongjiang\|Yao, Tianwei\|Li, Wenchuan\|Pu, Jian
PMID:	30317590

627.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2018 Aug 20;26(8):601-606.
Title:	[Mechanism of angiotensin II (Ang II) on the proliferation of human hepatoma cell line HepG2 cells].
Author:	Qi, R\|Lei, C G\|Bai, Y X\|Xing, X
PMID:	30317792

628.
Journal:	Cell Rep. 2018 Oct 16;25(3):690-701.e8.
Title:	PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation.
Author:	Chan, Lok Hei\|Zhou, Lei\|Ng, Kai Yu\|Wong, Tin Lok\|Lee, Terence K\|Sharma, Rakesh\|Loong, Jane H\|Ching, Yick Pang\|Yuan, Yun-Fei\|Xie, Dan\|Lo, Chung Mau\|Man, Kwan\|Artegiani, Benedetta\|Clevers, Hans\|Yan, Helen H\|Leung, Suet Yi\|Richard, Stephane\|Guan, Xin-Yuan\|Hu
PMID:	30332648

629.
Journal:	Biofactors. 2018 Sep;44(5):453-464.
Title:	SPARC acts as a mediator of TGF-beta1 in promoting epithelial-to-mesenchymal transition in A549 and H1299 lung cancer cells.
Author:	Sun, Weichao\|Feng, Jianguo\|Yi, Qian\|Xu, Xichao\|Chen, Ying\|Tang, Liling
PMID:	30346081

630.
Journal:	Mol Carcinog. 2018 Oct 26.
Title:	lncRNA DRHC inhibits proliferation and invasion in hepatocellular carcinoma via c-Myb-regulated MEK/ERK signaling.
Author:	Zhuang, Runzhou\|Zhang, Xuanyu\|Lu, Di\|Wang, Jianguo\|Zhuo, Jianyong\|Wei, Xuyong\|Ling, Qi\|Xie, Haiyang\|Zheng, Shusen\|Xu, Xiao
PMID:	30362626

631.
Journal:	Oncol Rep. 2018 Oct 25.
Title:	PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway.
Author:	Tang, Bo\|Liang, Wenjin\|Liao, Yong\|Li, Zeming\|Wang, Yan\|Yan, Chao
PMID:	30365128

632.
Journal:	Int J Mol Sci. 2018 Oct 31;19(11). pii: ijms19113419.
Title:	Evodiamine Induces Apoptosis in SMMC-7721 and HepG2 Cells by Suppressing NOD1 Signal Pathway.
Author:	Guo, Xing-Xian\|Li, Xiao-Peng\|Zhou, Peng\|Li, Dan-Yang\|Lyu, Xiao-Ting\|Chen, Yi\|Lyu, Yan-Wei\|Tian, Kuan\|Yuan, De-Zhi\|Ran, Jian-Hua\|Chen, Di-Long\|Jiang, Rong\|Li, Jing
PMID:	30384473