Primary Site >> Biliary tract Cancer

Gene >> EPHA2

Journal: PLoS One. 2011 Jan 6;6(1):e15640.
Title: Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.
Author: Gu, Ting-Lei|Deng, Xiaxing|Huang, Feizhou|Tucker, Meghan|Crosby, Katherine|Rimkunas, Victoria|Wang, Yi|Deng, Gang|Zhu, Lei|Tan, Zhiping|Hu, Yerong|Wu, Chunlin|Nardone, Julie|MacNeill, Joan|Ren, Jianmin|Reeves, Cynthia|Innocenti, Gregory|Norris, Brett|Yuan
PMID: 21253578
Journal: Hepatology. 2013 Jun;57(6):2248-60.
Title: Activation of mammalian target of rapamycin complex 1 (mTORC1) and Raf/Pyk2 by growth factor-mediated Eph receptor 2 (EphA2) is required for cholangiocarcinoma growth and metastasis.
Author: Cui, Xiang-Dan|Lee, Mi-Jin|Kim, Jong-Hyun|Hao, Pei-Pei|Liu, Lan|Yu, Goung-Ran|Kim, Dae-Ghon
PMID: 23315987
Journal: Int J Oncol. 2013 Jun;42(6):2103-15.
Title: Contribution of the PI3K/MMPs/Ln-5gamma2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Author: Lu, Xin-Sui|Sun, Wei|Ge, Chun-Yan|Zhang, Wen-Zhong|Fan, Yue-Zu
PMID: 23588386
Journal: PLoS One. 2014 May 8;9(5):e96982.
Title: Inhibition of tumor vasculogenic mimicry and prolongation of host survival in highly aggressive gallbladder cancers by norcantharidin via blocking the ephrin type a receptor 2/focal adhesion kinase/paxillin signaling pathway.
Author: Wang, Hui|Sun, Wei|Zhang, Wen-Zhong|Ge, Chun-Yan|Zhang, Jing-Tao|Liu, Zhong-Yan|Fan, Yue-Zu
PMID: 24811250