Primary Site >> Colorectal Cancer

Gene >> EP300

Journal: Oncogene. 1996 Apr 4;12(7):1565-9.
Title: p300 gene alterations in colorectal and gastric carcinomas.
Author: Muraoka, M|Konishi, M|Kikuchi-Yanoshita, R|Tanaka, K|Shitara, N|Chong, J M|Iwama, T|Miyaki, M
PMID: 8622873
Journal: Trends Genet. 1998 May;14(5):178-83.
Title: Conjunction dysfunction: CBP/p300 in human disease.
Author: Giles, R H|Peters, D J|Breuning, M H
PMID: 9613201
Journal: Mol Cell Biol. 1998 Jul;18(7):4377-84.
Title: Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.
Author: Jin, S|Scotto, K W
PMID: 9632821
Journal: Nat Genet. 2000 Mar;24(3):300-3.
Title: Mutations truncating the EP300 acetylase in human cancers.
Author: Gayther, S A|Batley, S J|Linger, L|Bannister, A|Thorpe, K|Chin, S F|Daigo, Y|Russell, P|Wilson, A|Sowter, H M|Delhanty, J D|Ponder, B A|Kouzarides, T|Caldas, C
PMID: 10700188
Journal: Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12613-8.
Title: Regulation of beta -catenin transformation by the p300 transcriptional coactivator.
Author: Sun, Y|Kolligs, F T|Hottiger, M O|Mosavin, R|Fearon, E R|Nabel, G J
PMID: 11050151
Journal: EMBO J. 2001 Sep 3;20(17):4935-43.
Title: The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation.
Author: Barker, N|Hurlstone, A|Musisi, H|Miles, A|Bienz, M|Clevers, H
PMID: 11532957
Journal: J Virol. 2001 Oct;75(20):9844-56.
Title: Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.
Author: Chattopadhyay, D|Ghosh, M K|Mal, A|Harter, M L
PMID: 11559818
Journal: Gene Ther. 2002 Feb;9(4):270-81.
Title: Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway.
Author: Fuerer, C|Iggo, R
PMID: 11896466
Journal: Nucleic Acids Res. 2002 Aug 1;30(15):3312-22.
Title: Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism.
Author: Prochasson, Philippe|Delouis, Cecile|Brison, Olivier
PMID: 12140315
Journal: Int J Cancer. 2002 Nov 10;102(2):137-41.
Title: Mutation analysis of EP300 in colon, breast and ovarian carcinomas.
Author: Bryan, Emma J|Jokubaitis, Venta J|Chamberlain, Narelle L|Baxter, Simon W|Dawson, Elisabeth|Choong, David Y H|Campbell, Ian G
PMID: 12385008
Journal: Biol Pharm Bull. 2002 Oct;25(10):1298-302.
Title: Role of coactivators and corepressors in the induction of the RARbeta gene in human colon cancer cells.
Author: Lee, Mi-Ock|Kang, Hyo-Jin
PMID: 12392082
Journal: Cancer Sci. 2004 Jan;95(1):52-7.
Title: Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB.
Author: Yasuda, Jun|Yokoo, Hideki|Yamada, Tesshi|Kitabayashi, Issay|Sekiya, Takao|Ichikawa, Hitoshi
PMID: 14720327
Journal: Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1273-8. Epub 2004 Jan 19.
Title: A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability.
Author: Ionov, Yurij|Matsui, Sei-Ichi|Cowell, John K
PMID: 14732695
Journal: Oncogene. 2004 Jan 22;23(3):639-45.
Title: Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability.
Author: Ionov, Yurij|Nowak, Norma|Perucho, Manuel|Markowitz, Sanford|Cowell, John K
PMID: 14737099
Journal: J Biol Chem. 2004 Apr 30;279(18):18694-700. Epub 2004 Feb 19.
Title: Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells.
Author: Liu, Yongmin|Borchert, Gregory L|Phang, James M
PMID: 14976201
Journal: Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author: Campbell, Ian G|Choong, David|Chenevix-Trench, Georgia
PMID: 15217503
Journal: Oncogene. 2005 May 19;24(22):3619-31.
Title: Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression.
Author: Ma, Hong|Nguyen, Cu|Lee, Kyung-Soon|Kahn, Michael
PMID: 15782138
Journal: Endocr Rev. 2005 Dec;26(7):898-915. Epub 2005 Aug 26.
Title: Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?
Author: Mulholland, David J|Dedhar, Shoukat|Coetzee, Gerhard A|Nelson, Colleen C
PMID: 16126938
Journal: Mol Cancer Ther. 2005 Oct;4(10):1521-32.
Title: Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity.
Author: Stimson, Lindsay|Rowlands, Martin G|Newbatt, Yvette M|Smith, Nicola F|Raynaud, Florence I|Rogers, Paul|Bavetsias, Vassilios|Gorsuch, Stephen|Jarman, Michael|Bannister, Andrew|Kouzarides, Tony|McDonald, Edward|Workman, Paul|Aherne, G Wynne
PMID: 16227401
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4287-92.
Title: Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma.
Author: Giannini, Romina|Cavallini, Aldo
PMID: 16309230
Journal: Int J Mol Med. 2006 Apr;17(4):681-5.
Title: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16525728
Journal: Br J Cancer. 2006 May 8;94(9):1326-32.
Title: Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition.
Author: Krubasik, D|Iyer, N G|English, W R|Ahmed, A A|Vias, M|Roskelley, C|Brenton, J D|Caldas, C|Murphy, G
PMID: 16622451
Journal: Int J Cancer. 2006 Nov 1;119(9):2098-104.
Title: The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas.
Author: Pena, Cristina|Garcia, Jose Miguel|Garcia, Vanesa|Silva, Javier|Dominguez, Gemma|Rodriguez, Rufo|Maximiano, Constanza|Garcia de Herreros, Antonio|Munoz, Alberto|Bonilla, Felix
PMID: 16804902
Journal: Cancer Res. 2006 Aug 1;66(15):7606-14.
Title: Metabolic consequences of p300 gene deletion in human colon cancer cells.
Author: Bundy, Jacob G|Iyer, N Gopalakrishna|Gentile, Michelle S|Hu, De-En|Kettunen, Mikko|Maia, Ana-Teresa|Thorne, Natalie P|Brenton, James D|Caldas, Carlos|Brindle, Kevin M
PMID: 16885360
Journal: J Pathol. 2006 Dec;210(4):390-7.
Title: The presence of an intronic deletion in p73 and high levels of ZEB1 alter the TAp73/DeltaTAp73 ratio in colorectal carcinomas.
Author: Dominguez, G|Pena, C|Silva, J|Garcia, J M|Garcia, V|Rodriguez, R|Cantos, B|Citores, M J|Espana, P|Bonilla, F
PMID: 17029218
Journal: J Pathol. 2006 Dec;210(4):385-9.
Title: Regulating p73 isoforms in human tumours.
Author: Coates, P J
PMID: 17044134
Journal: Steroids. 2007 Feb;72(2):221-30. Epub 2007 Feb 7.
Title: The functional significance of nuclear receptor acetylation.
Author: Popov, Vladimir M|Wang, Chenguang|Shirley, L Andrew|Rosenberg, Anne|Li, Shengwen|Nevalainen, Marja|Fu, Maofu|Pestell, Richard G
PMID: 17291555
Journal: EMBO J. 2007 May 2;26(9):2284-94. Epub 2007 Apr 5.
Title: CBP/p300 are bimodal regulators of Wnt signaling.
Author: Li, Jiong|Sutter, Chris|Parker, David S|Blauwkamp, Timothy|Fang, Ming|Cadigan, Ken M
PMID: 17410209
Journal: J Clin Pathol. 2007 Nov;60(11):1205-10. Epub 2007 Aug 24.
Title: Expression of HDAC1 and CBP/p300 in human colorectal carcinomas.
Author: Ishihama, Katsuyoshi|Yamakawa, Mitsunori|Semba, Shuho|Takeda, Hiroaki|Kawata, Sumio|Kimura, Seishi|Kimura, Wataru
PMID: 17720775
Journal: J Biol Chem. 2007 Nov 23;282(47):33994-4002.
Title: Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Author: Evans, Paul M|Zhang, Wen|Chen, Xi|Yang, Jun|Bhakat, Kishor K|Liu, Chunming
PMID: 17908689
Journal: FEBS Lett. 2007 Dec 22;581(30):5904-10. Epub 2007 Dec 3.
Title: A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion.
Author: Bai, Longchuan|Merchant, Juanita L
PMID: 18054336
Journal: J Nutr Sci Vitaminol (Tokyo). 2008 Aug;54(4):298-302.
Title: PPAR alpha and PPAR delta transactivity and p300 binding activity induced by arachidonic acid in colorectal cancer cell line Caco-2.
Author: Mochizuki, Kazuki|Suzuki, Takuji|Goda, Toshinao
PMID: 18797151
Journal: J Biol Chem. 2008 Nov 14;283(46):31341-7.
Title: Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells.
Author: Zuo, Xiangsheng|Morris, Jeffrey S|Shureiqi, Imad
PMID: 18799463
Journal: Biochem Biophys Res Commun. 2008 Dec 26;377(4):1304-8.
Title: Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.
Author: Ryu, Min-Jung|Cho, Munju|Song, Jie-Young|Yun, Yeon-Sook|Choi, Il-Whan|Kim, Dong-Eun|Park, Byeoung-Soo|Oh, Sangtaek
PMID: 19000900
Journal: J Biol Chem. 2009 May 8;284(19):13033-44.
Title: The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.
Author: Kimbrel, Erin A|Kung, Andrew L
PMID: 19297328
Journal: Cancer Res. 2009 May 1;69(9):3736-45.
Title: Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Author: Kumar, S Ram|Scehnet, Jeffrey S|Ley, Eric J|Singh, Jasbir|Krasnoperov, Valery|Liu, Ren|Manchanda, Parmeet K|Ladner, Robert D|Hawes, Debra|Weaver, Fred A|Beart, Robert W|Singh, Gagandeep|Nguyen, Cu|Kahn, Michael|Gill, Parkash S
PMID: 19366806
Journal: Mol Cell Biol. 2010 Jan;30(2):372-81.
Title: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.
Author: Evans, Paul M|Chen, Xi|Zhang, Wen|Liu, Chunming
PMID: 19901072
Journal: Cancer Res. 2010 May 15;70(10):4054-63.
Title: Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells.
Author: Kim, Sun-Hee|Xia, Dianren|Kim, Sang-Wook|Holla, Vijaykumar|Menter, David G|Dubois, Raymond N
PMID: 20442290
Journal: Nutr Cancer. 2010;62(7):919-30.
Title: Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
Author: Goel, Ajay|Aggarwal, Bharat B
PMID: 20924967
Journal: PLoS Biol. 2010 Nov 16;8(11):e1000539.
Title: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis.
Author: Mahmoudi, Tokameh|Boj, Sylvia F|Hatzis, Pantelis|Li, Vivian S W|Taouatas, Nadia|Vries, Robert G J|Teunissen, Hans|Begthel, Harry|Korving, Jeroen|Mohammed, Shabaz|Heck, Albert J R|Clevers, Hans
PMID: 21103407
Journal: PLoS One. 2010 Dec 31;5(12):e16012.
Title: Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability.
Author: Williams, David S|Bird, Matthew J|Jorissen, Robert N|Yu, Yen Lin|Walker, Francesca|Zhang, Hui Hua|Nice, Edouard C|Burgess, Antony W
PMID: 21209843
Journal: J Gastroenterol. 2011 Mar;46(3):339-49.
Title: CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid.
Author: Yoshida, Tsutomu|Sekine, Tsukasa|Aisaki, Ken-ichi|Mikami, Tetuo|Kanno, Jun|Okayasu, Isao
PMID: 21165656
Journal: PLoS One. 2011;6(8):e23754.
Title: PTTG1 attenuates drug-induced cellular senescence.
Author: Tong, Yunguang|Zhao, Weijiang|Zhou, Cuiqi|Wawrowsky, Kolja|Melmed, Shlomo
PMID: 21858218
Journal: J Agric Food Chem. 2012 Apr 4;60(13):3441-51.
Title: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.
Author: Chiou, Yi-Shiou|Ma, Nianhan Jia-Lin|Sang, Shengmin|Ho, Chi-Tang|Wang, Ying-Jan|Pan, Min-Hsiung
PMID: 22409325
Journal: Rev Med Chir Soc Med Nat Iasi. 2012 Oct-Dec;116(4):1106-11.
Title: Colon cancer at the molecular level--usefulness of epithelial-mesenchymal transition analysis.
Author: Todosi, Ana-Maria|Gavrilescu, Mihaela-Madalina|Anitei, Gabriela-Maria|Filip, B|Scripcariu, V
PMID: 23700897
Journal: J Pineal Res. 2013 May;54(4):406-16.
Title: Melatonin potentiates the antiproliferative and pro-apoptotic effects of ursolic acid in colon cancer cells by modulating multiple signaling pathways.
Author: Wang, Jingshu|Guo, Wei|Chen, Wangbing|Yu, Wendan|Tian, Yun|Fu, Lingyi|Shi, Dingbo|Tong, Bing|Xiao, Xiangsheng|Huang, Wenlin|Deng, Wuguo
PMID: 23330808
Journal: Clin Cancer Res. 2013 Mar 1;19(5):1071-82.
Title: ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.
Author: Sanchez-Tillo, Ester|de Barrios, Oriol|Siles, Laura|Amendola, Pier G|Darling, Douglas S|Cuatrecasas, Miriam|Castells, Antoni|Postigo, Antonio
PMID: 23340304
Journal: Cell Death Dis. 2013 Apr 25;4:e605.
Title: The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis.
Author: Sampurno, S|Bijenhof, A|Cheasley, D|Xu, H|Robine, S|Hilton, D|Alexander, W S|Pereira, L|Mantamadiotis, T|Malaterre, J|Ramsay, R G
PMID: 23618903
Journal: PLoS One. 2013 May 30;8(5):e63872.
Title: Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
Author: Wang, Jingshu|Liu, Liqun|Qiu, Huijuan|Zhang, Xiaohong|Guo, Wei|Chen, Wangbing|Tian, Yun|Fu, Lingyi|Shi, Dingbo|Cheng, Jianding|Huang, Wenlin|Deng, Wuguo
PMID: 23737956
Journal: Hum Pathol. 2013 Oct;44(10):2064-70.
Title: Frameshift mutations of tumor suppressor gene EP300 in gastric and colorectal cancers with high microsatellite instability.
Author: Kim, Min Sung|Lee, Sung Hak|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 23759652
Journal: J Cancer. 2013 Jul 18;4(6):491-501.
Title: p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells.
Author: Lazarova, Darina L|Wong, Terrence|Chiaro, Christopher|Drago, Eric|Bordonaro, Michael
PMID: 23901349
Journal: J Surg Oncol. 2013 Nov;108(6):374-7.
Title: Prognostic impact of p300 expression in patients with colorectal cancer.
Author: Huh, Jung Wook|Kim, Hee Cheol|Kim, Seok Hyung|Park, Yoon Ah|Cho, Yong Beom|Yun, Seong Hyeon|Lee, Woo Yong|Chun, Ho-Kyung
PMID: 24142575
Journal: Biochem Biophys Res Commun. 2014 Feb 14;444(3):387-90.
Title: P300 binds to and acetylates MTA2 to promote colorectal cancer cells growth.
Author: Zhou, Jun|Zhan, Songhua|Tan, Wenli|Cheng, Ruixin|Gong, Hangjun|Zhu, Qiong
PMID: 24468085
Journal: J Biol Chem. 2014 Mar 28;289(13):8881-90.
Title: Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.
Author: Xu, Xuehe|Yu, Tianxin|Shi, Jiandang|Chen, Xi|Zhang, Wen|Lin, Ting|Liu, Zhihong|Wang, Yadong|Zeng, Zheng|Wang, Chi|Li, Mingsong|Liu, Chunming
PMID: 24532795
Journal: J Cancer. 2014 Feb 14;5(3):203-13.
Title: Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells.
Author: Lazarova, Darina|Lee, Andrew|Wong, Terrence|Marian, Brigitte|Chiaro, Christopher|Rainey, Christian|Bordonaro, Michael
PMID: 24563675
Journal: Mol Carcinog. 2014 Nov;53(11):926-37.
Title: PPARdelta deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells.
Author: Jeong, Eunshil|Koo, Jung Eun|Yeon, Sang Hyeon|Kwak, Mi-Kyoung|Hwang, Daniel H|Lee, Joo Young
PMID: 24610641
Journal: Cancer Res. 2014 Jun 15;74(12):3238-47.
Title: Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Author: Mouradov, Dmitri|Sloggett, Clare|Jorissen, Robert N|Love, Christopher G|Li, Shan|Burgess, Antony W|Arango, Diego|Strausberg, Robert L|Buchanan, Daniel|Wormald, Samuel|O'Connor, Liam|Wilding, Jennifer L|Bicknell, David|Tomlinson, Ian P M|Bodmer, Walter F|M
PMID: 24755471
Journal: J Nat Prod. 2014 May 23;77(5):1130-4.
Title: Plumbagin downregulates Wnt signaling independent of p53 in human colorectal cancer cells.
Author: Raghu, Dinesh|Karunagaran, Devarajan
PMID: 24828199
Journal: Eur J Med Chem. 2014 Jun 10;80:569-78.
Title: Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: enzyme and cellular studies.
Author: Carradori, Simone|Rotili, Dante|De Monte, Celeste|Lenoci, Alessia|D'Ascenzio, Melissa|Rodriguez, Veronica|Filetici, Patrizia|Miceli, Marco|Nebbioso, Angela|Altucci, Lucia|Secci, Daniela|Mai, Antonello
PMID: 24835815
Journal: FASEB J. 2014 Oct;28(10):4265-79.
Title: Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators.
Author: Yang, Hui|Salz, Tal|Zajac-Kaye, Maria|Liao, Daiqing|Huang, Suming|Qiu, Yi
PMID: 24948597
Journal: Nat Commun. 2014 Aug 26;5:4735.
Title: ArhGAP30 promotes p53 acetylation and function in colorectal cancer.
Author: Wang, Jilin|Qian, Jin|Hu, Ye|Kong, Xuan|Chen, Haoyan|Shi, Qinghua|Jiang, Long|Wu, Chenming|Zou, Weiping|Chen, Yingxuan|Xu, Jie|Fang, Jing-Yuan
PMID: 25156493
Journal: Eur J Pharmacol. 2014 Nov 5;742:55-64.
Title: Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620.
Author: Pooja, Thacker|Karunagaran, Devarajan
PMID: 25205133
Journal: Nucleic Acids Res. 2014 Oct;42(18):11447-61.
Title: Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.
Author: Jeon, Bu-Nam|Kim, Min-Kyeong|Yoon, Jae-Hyeon|Kim, Min-Young|An, Haemin|Noh, Hee-Jin|Choi, Won-Il|Koh, Dong-In|Hur, Man-Wook
PMID: 25245946
Journal: Cell Death Dis. 2014 Oct 16;5:e1476.
Title: HDAC8 and STAT3 repress BMF gene activity in colon cancer cells.
Author: Kang, Y|Nian, H|Rajendran, P|Kim, E|Dashwood, W M|Pinto, J T|Boardman, L A|Thibodeau, S N|Limburg, P J|Lohr, C V|Bisson, W H|Williams, D E|Ho, E|Dashwood, R H
PMID: 25321483
Journal: Mol Oncol. 2015 Feb;9(2):335-54.
Title: SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
Author: Ronsch, Kerstin|Jagle, Sabine|Rose, Katja|Seidl, Maximilian|Baumgartner, Francis|Freihen, Vivien|Yousaf, Afsheen|Metzger, Eric|Lassmann, Silke|Schule, Roland|Zeiser, Robert|Michoel, Tom|Hecht, Andreas
PMID: 25277775
Journal: Oncogene. 2015 Nov 19;34(47):5781-95.
Title: The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.
Author: Wang, J|Tang, X|Weng, W|Qiao, Y|Lin, J|Liu, W|Liu, R|Ma, L|Yu, W|Yu, Y|Pan, Q|Sun, F
PMID: 25728681
Journal: Cancer Immunol Res. 2015 Jul;3(7):795-805.
Title: IFNgamma Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer.
Author: Bardhan, Kankana|Paschall, Amy V|Yang, Dafeng|Chen, May R|Simon, Priscilla S|Bhutia, Yangzom D|Martin, Pamela M|Thangaraju, Muthusamy|Browning, Darren D|Ganapathy, Vadivel|Heaton, Christopher M|Gu, Keni|Lee, Jeffrey R|Liu, Kebin
PMID: 25735954
Journal: Cell Stem Cell. 2015 Jul 2;17(1):47-59.
Title: TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells.
Author: Wu, ZhengMing|Wei, Dong|Gao, WenChao|Xu, YuTing|Hu, ZhiQian|Ma, ZhenYu|Gao, ChunFang|Zhu, XiaoYan|Li, QingQuan
PMID: 26140605
Journal: Nucleic Acids Res. 2015 Sep 18;43(16):7878-87.
Title: Acetylation-dependent function of human single-stranded DNA binding protein 1.
Author: Wu, Yuanzhong|Chen, Hongxia|Lu, Jinping|Zhang, Meifang|Zhang, Ruhua|Duan, Tingmei|Wang, Xin|Huang, Jun|Kang, Tiebang
PMID: 26170237
Journal: Epigenetics Chromatin. 2015 Feb 24;8:9.
Title: Altering cancer transcriptomes using epigenomic inhibitors.
Author: Gaddis, Malaina|Gerrard, Diana|Frietze, Seth|Farnham, Peggy J
PMID: 26191083
Journal: World J Gastroenterol. 2015 Jul 21;21(27):8238-48.
Title: CREB-binding protein, p300, butyrate, and Wnt signaling in colorectal cancer.
Author: Bordonaro, Michael|Lazarova, Darina L
PMID: 26217075
Journal: Oncogene. 2015 Nov 12;34(46):5760-70.
Title: ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression.
Author: Sanchez-Tillo, E|de Barrios, O|Valls, E|Darling, D S|Castells, A|Postigo, A
PMID: 26387539
Journal: Cell Death Differ. 2016 Apr;23(4):707-22.
Title: DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.
Author: Alam, S K|Yadav, V K|Bajaj, S|Datta, A|Dutta, S K|Bhattacharyya, M|Bhattacharya, S|Debnath, S|Roy, S|Boardman, L A|Smyrk, T C|Molina, J R|Chakrabarti, S|Chowdhury, S|Mukhopadhyay, D|Roychoudhury, S
PMID: 26494468
Journal: Gastroenterology. 2016 Apr;150(4):931-43.
Title: Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Author: Robles, Ana I|Traverso, Giovanni|Zhang, Ming|Roberts, Nicholas J|Khan, Mohammed A|Joseph, Christine|Lauwers, Gregory Y|Selaru, Florin M|Popoli, Maria|Pittman, Meredith E|Ke, Xiquan|Hruban, Ralph H|Meltzer, Stephen J|Kinzler, Kenneth W|Vogelstein, Bert|Har
PMID: 26764183
Journal: Mol Cancer Res. 2016 Apr;14(4):385-96.
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Author: Ghaleb, Amr M|Elkarim, Enas A|Bialkowska, Agnieszka B|Yang, Vincent W
PMID: 26839262
Journal: Front Med. 2016 Jun;10(2):178-82.
Title: Bioinformatic exploration of MTA1-regulated gene networks in colon cancer.
Author: Li, Chunxiao|Wang, Haijuan|Lin, Feng|Li, Hui|Wen, Tao|Qian, Haili|Zhan, Qimin
PMID: 27052252
Journal: J Nat Prod. 2016 May 27;79(5):1267-75.
Title: Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1alpha/p300 Interaction.
Author: Goey, Andrew K L|Chau, Cindy H|Sissung, Tristan M|Cook, Kristina M|Venzon, David J|Castro, Amaya|Ransom, Tanya R|Henrich, Curtis J|McKee, Tawnya C|McMahon, James B|Grkovic, Tanja|Cadelis, Melissa M|Copp, Brent R|Gustafson, Kirk R|Figg, William D
PMID: 27140429
Journal: JMIR Res Protoc. 2016 May 13;5(2):e66.
Title: Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells.
Author: Bordonaro, Michael|Lazarova, Darina Lazarova
PMID: 27177606
Journal: Oncotarget. 2016 Jul 5;7(27):42513-42526.
Title: Wnt/beta-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling.
Author: Guo, Yan-Hua|Wang, Lu-Qin|Li, Bin|Xu, Hui|Yang, Jian-Hua|Zheng, Li-Si|Yu, Peng|Zhou, Ai-Dong|Zhang, Yin|Xie, Shu-Juan|Liang, Zi-Rui|Zhang, Chen-Min|Zhou, Hui|Qu, Liang-Hu
PMID: 27285761
Journal: Mol Cell. 2016 Nov 17;64(4):803-814.
Title: TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.
Author: Zhang, Xian|Li, Chien-Feng|Zhang, Ling|Wu, Ching-Yuan|Han, Lixia|Jin, Guoxiang|Rezaeian, Abdol Hossein|Han, Fei|Liu, Chunfang|Xu, Chuan|Xu, Xiaohong|Huang, Chih-Yang|Tsai, Fuu-Jen|Tsai, Chang-Hai|Watabe, Kounosuke|Lin, Hui-Kuan
PMID: 27818144
Journal: PLoS One. 2017 Jan 9;12(1):e0168989.
Title: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author: Huang, Wen-Shih|Kuo, Yi-Hung|Kuo, Hsing-Chun|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Lee, Ko-Chao|Lee, Kam-Fai|Shen, Chien-Heng|Tung, Shui-Yi|Teng, Chih-Chuan
PMID: 28068431
Journal: Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title: Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author: Lee, Sung Hak|Jung, Seung Hyun|Kim, Tae-Min|Rhee, Je-Keun|Park, Hyeon-Chun|Kim, Min Sung|Kim, Sung Soo|An, Chang Hyeok|Lee, Sug Hyung|Chung, Yeun-Jun
PMID: 28179590
Journal: Breast Cancer Res Treat. 2017 Jun;163(3):461-474.
Title: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Author: Asaduzzaman, Muhammad|Constantinou, Stephanie|Min, Haoxiang|Gallon, John|Lin, Meng-Lay|Singh, Poonam|Raguz, Selina|Ali, Simak|Shousha, Sami|Coombes, R Charles|Lam, Eric W-F|Hu, Yunhui|Yague, Ernesto
PMID: 28341962
Journal: Cancer Lett. 2017 Aug 1;400:183-193.
Title: 5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.
Author: Du, Changzheng|Huang, Dandan|Peng, Yifan|Yao, Yunfeng|Zhao, Ying|Yang, Yang|Wang, Haiying|Cao, Linlin|Zhu, Wei-Guo|Gu, Jin
PMID: 28465257
Journal: Oncol Rep. 2017 Jul;38(1):201-210.
Title: Expression of the EP300, TP53 and BAX genes in colorectal cancer: Correlations with clinicopathological parameters and survival.
Author: Kowalczyk, Anna E|Krazinski, Bartlomiej E|Godlewski, Janusz|Kiewisz, Jolanta|Kwiatkowski, Przemyslaw|Sliwinska-Jewsiewicka, Agnieszka|Kiezun, Jacek|Sulik, Marian|Kmiec, Zbigniew
PMID: 28586030
Journal: J Cancer. 2017 May 12;8(8):1453-1459.
Title: ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC.
Author: Lazarova, Darina|Bordonaro, Michael
PMID: 28638460
Journal: Cancer Res. 2017 Aug 15;77(16):4342-4354.
Title: Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity.
Author: Zheng, Shunsheng|Koh, Xin Yu|Goh, Hui Chin|Rahmat, Siti Aishah B|Hwang, Le-Ann|Lane, David P
PMID: 28655792
Journal: Cell Death Differ. 2017 Oct;24(10):1811-1820.
Title: Blocking endothelin-1-receptor/beta-catenin circuit sensitizes to chemotherapy in colorectal cancer.
Author: Cianfrocca, Roberta|Rosano, Laura|Tocci, Piera|Sestito, Rosanna|Caprara, Valentina|Di Castro, Valeriana|De Maria, Ruggero|Bagnato, Anna
PMID: 28708138
Journal: World J Gastroenterol. 2017 Jul 7;23(25):4480-4490.
Title: Expression and role of nuclear receptor coregulators in colorectal cancer.
Author: Triki, Mouna|Lapierre, Marion|Cavailles, Vincent|Mokdad-Gargouri, Raja
PMID: 28740336
Journal: Gene. 2017 Sep 20;629:16-28.
Title: Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia.
Author: Bhan, Arunoday|Deb, Paromita|Shihabeddin, Nadine|Ansari, Khairul I|Brotto, Marco|Mandal, Subhrangsu S
PMID: 28756022
Journal: Sci Rep. 2017 Sep 15;7(1):11678.
Title: Inhibition of Wnt/beta-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer.
Author: Proto, Maria Chiara|Fiore, Donatella|Piscopo, Chiara|Franceschelli, Silvia|Bizzarro, Valentina|Laezza, Chiara|Lauro, Gianluigi|Feoli, Alessandra|Tosco, Alessandra|Bifulco, Giuseppe|Sbardella, Gianluca|Bifulco, Maurizio|Gazzerro, Patrizia
PMID: 28916833
Journal: PLoS One. 2017 Oct 19;12(10):e0186900.
Title: XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Author: Zhang, Zhifeng|Zheng, Fufu|Yu, Zhenlong|Hao, Jiajiao|Chen, Miao|Yu, Wendan|Guo, Wei|Chen, Yiming|Huang, Wenlin|Duan, Zhijun|Deng, Wuguo
PMID: 29049411
Journal: Oncotarget. 2017 Aug 18;8(42):72773-72787.
Title: Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300.
Author: Ling, Feng|Tang, Yi|Li, Ming|Li, Qing-Shu|Li, Xian|Yang, Lian|Zhao, Wei|Jin, Cong-Cong|Zeng, Zhen|Liu, Chang|Wu, Cheng-Fang|Chen, Wen-Wen|Lin, Xiao|Wang, Ya-Lan|Threadgill, Michael D
PMID: 29069825
Journal: J Cancer. 2017 Sep 20;8(17):3405-3409.
Title: p300 Knockout Promotes Butyrate Resistance.
Author: Lazarova, Darina L|Bordonaro, Michael
PMID: 29151923
Journal: Front Pharmacol. 2018 Jan 4;8:949.
Title: Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids.
Author: Fiore, Donatella|Ramesh, Prashanthi|Proto, Maria C|Piscopo, Chiara|Franceschelli, Silvia|Anzelmo, Serena|Medema, Jan P|Bifulco, Maurizio|Gazzerro, Patrizia
PMID: 29354056
Journal: Am J Med Genet A. 2018 Mar;176(3):597-608.
Title: Benign and malignant tumors in Rubinstein-Taybi syndrome.
Author: Boot, Max V|van Belzen, Martine J|Overbeek, Lucy I|Hijmering, Nathalie|Mendeville, Matias|Waisfisz, Quinten|Wesseling, Pieter|Hennekam, Raoul C|de Jong, Daphne
PMID: 29359884
Journal: Gastroenterology. 2018 Jun;154(8):2209-2221.e14.
Title: P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Author: Dou, Changwei|Liu, Zhikui|Tu, Kangsheng|Zhang, Hongbin|Chen, Chen|Yaqoob, Usman|Wang, Yuanguo|Wen, Jialing|van Deursen, Jan|Sicard, Delphine|Tschumperlin, Daniel|Zou, Hongzhi|Huang, Wei-Chien|Urrutia, Raul|Shah, Vijay H|Kang, Ningling
PMID: 29454793
Journal: Oncogene. 2018 Jun;37(26):3485-3500.
Title: CREPT facilitates colorectal cancer growth through inducing Wnt/beta-catenin pathway by enhancing p300-mediated beta-catenin acetylation.
Author: Zhang, Yanquan|Wang, Shiyan|Kang, Wei|Liu, Chunxiao|Dong, Yujuan|Ren, Fangli|Wang, Yinyin|Zhang, Jinglin|Wang, Guoping|To, Ka Fai|Zhang, Xueji|Sung, Joseph Jy|Chang, Zhijie|Yu, Jun
PMID: 29563608
Journal: Clin Epigenetics. 2018 Apr 4;10:44.
Title: KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.
Author: Cocco, Elisa|Leo, Manuela|Canzonetta, Claudia|Di Vito, Serena|Mai, Antonello|Rotili, Dante|Di Napoli, Arianna|Vecchione, Andrea|De Nunzio, Cosimo|Filetici, Patrizia|Stoppacciaro, Antonella
PMID: 29632619
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: J Biol Chem. 2018 Aug 24;293(34):13234-13246.
Title: Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
Author: Rahnamoun, Homa|Hong, Juyeong|Sun, Zhengxi|Lee, Jihoon|Lu, Hanbin|Lauberth, Shannon M
PMID: 29954944
Journal: Theranostics. 2018 Aug 7;8(16):4447-4461.
Title: Aspirin cooperates with p300 to activate the acetylation of H3K9 and promote FasL-mediated apoptosis of cancer stem-like cells in colorectal cancer.
Author: Chen, Zhigang|Li, Wenlu|Qiu, Fuming|Huang, Qi|Jiang, Zhou|Ye, Jun|Cheng, Pu|Low, Cho|Guo, Yikun|Yi, Xinchi|Chen, Wenteng|Yu, Yongpin|Han, YueHua|Wu, Jun|Jin, Shenghang|Kong, Dong|Huang, Jian
PMID: 30214631