Primary Site >> Colorectal Cancer
Gene >> EIF4EBP1
| 1. | |||||||||||
| Journal: | J Biol Chem. 2002 Aug 2;277(31):28127-34. Epub 2002 May 8. | ||||||||||
| Title: | Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture. | ||||||||||
| Author: | Zhang, Xiongwen|Shu, Lili|Hosoi, Hajime|Murti, K Gopal|Houghton, Peter J | ||||||||||
| PMID: | 12000755 | ||||||||||
| 2. | |||||||||||
| Journal: | Anticancer Drugs. 2005 Jun;16(5):533-41. | ||||||||||
| Title: | The patellazoles inhibit protein synthesis at nanomolar concentrations in human colon tumor cells. | ||||||||||
| Author: | Richardson, Adam D|Aalbersberg, William|Ireland, Chris M | ||||||||||
| PMID: | 15846119 | ||||||||||
| 3. | |||||||||||
| Journal: | Carcinogenesis. 2006 Jul;27(7):1323-33. Epub 2006 Mar 10. | ||||||||||
| Title: | Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis. | ||||||||||
| Author: | Provenzani, Alessandro|Fronza, Raffaele|Loreni, Fabrizio|Pascale, Alessia|Amadio, Marialaura|Quattrone, Alessandro | ||||||||||
| PMID: | 16531451 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2007 Apr 15;67(8):3569-73. | ||||||||||
| Title: | Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. | ||||||||||
| Author: | Hu, Jing|Straub, Jonathan|Xiao, Dong|Singh, Shivendra V|Yang, Hsin-Sheng|Sonenberg, Nahum|Vatsyayan, Jaya | ||||||||||
| PMID: | 17440067 | ||||||||||
| 5. | |||||||||||
| Journal: | J Clin Oncol. 2008 Apr 1;26(10):1603-10. | ||||||||||
| Title: | Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors. | ||||||||||
| Author: | Tabernero, Josep|Rojo, Federico|Calvo, Emiliano|Burris, Howard|Judson, Ian|Hazell, Katharine|Martinelli, Erika|Ramon y Cajal, Santiago|Jones, Suzanne|Vidal, Laura|Shand, Nicholas|Macarulla, Teresa|Ramos, Francisco Javier|Dimitrijevic, Sasa|Zoellner, Ulrik | ||||||||||
| PMID: | 18332469 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann Surg Oncol. 2009 Sep;16(9):2617-28. | ||||||||||
| Title: | mTOR signaling pathway is a target for the treatment of colorectal cancer. | ||||||||||
| Author: | Zhang, Yan-Jie|Dai, Qiang|Sun, Dan-Feng|Xiong, Hua|Tian, Xiao-Qing|Gao, Feng-Hou|Xu, Mang-Hua|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan | ||||||||||
| PMID: | 19517193 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cancer Ther. 2010 Dec;9(12):3158-63. | ||||||||||
| Title: | Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis. | ||||||||||
| Author: | Dumstorf, Chad A|Konicek, Bruce W|McNulty, Ann M|Parsons, Stephen H|Furic, Luc|Sonenberg, Nahum|Graff, Jeremy R | ||||||||||
| PMID: | 20971826 | ||||||||||
| 8. | |||||||||||
| Journal: | Ann Surg Oncol. 2011 Feb;18(2):580-8. | ||||||||||
| Title: | mTOR signaling is involved in indomethacin and nimesulide suppression of colorectal cancer cell growth via a COX-2 independent pathway. | ||||||||||
| Author: | Zhang, Yan-Jie|Bao, Yu-Jie|Dai, Qiang|Yang, Wen-Yan|Cheng, Peng|Zhu, Li-Ming|Wang, Bi-Jun|Jiang, Fo-Hu | ||||||||||
| PMID: | 20803081 | ||||||||||
| 9. | |||||||||||
| Journal: | Eur J Cancer. 2012 Feb;48(3):396-406. | ||||||||||
| Title: | The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy. | ||||||||||
| Author: | Hernlund, Emma|Olofsson, Maria Hagg|Fayad, Walid|Fryknas, Marten|Lesiak-Mieczkowska, Karolina|Zhang, Xiaonan|Brnjic, Slavica|Schmidt, Vivien|D'Arcy, Padraig|Sjoblom, Tobias|De Milito, Angelo|Larsson, Rolf|Linder, Stig | ||||||||||
| PMID: | 22154651 | ||||||||||
| 10. | |||||||||||
| Journal: | Cell Cycle. 2012 Feb 1;11(3):594-603. | ||||||||||
| Title: | mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors. | ||||||||||
| Author: | Zhang, Yanjie|Zheng, X F Steven | ||||||||||
| PMID: | 22262166 | ||||||||||
| 11. | |||||||||||
| Journal: | Br J Cancer. 2012 Apr 10;106(8):1386-94. | ||||||||||
| Title: | The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition. | ||||||||||
| Author: | Haagensen, E J|Kyle, S|Beale, G S|Maxwell, R J|Newell, D R | ||||||||||
| PMID: | 22415236 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Oncol. 2013 Jun;42(6):2134-40. | ||||||||||
| Title: | Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse. | ||||||||||
| Author: | Manne, Nandini D P K|Lima, M|Enos, R T|Wehner, P|Carson, J A|Blough, Eric | ||||||||||
| PMID: | 23589074 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2013 Dec 10;8(12):e81763. | ||||||||||
| Title: | The enhanced in vivo activity of the combination of a MEK and a PI3K inhibitor correlates with [18F]-FLT PET in human colorectal cancer xenograft tumour-bearing mice. | ||||||||||
| Author: | Haagensen, Emma J|Thomas, Huw D|Wilson, Ian|Harnor, Suzannah J|Payne, Sara L|Rennison, Tommy|Smith, Kate M|Maxwell, Ross J|Newell, David R | ||||||||||
| PMID: | 24339963 | ||||||||||
| 14. | |||||||||||
| Journal: | Eur J Cancer. 2013 Oct;49(15):3311-9. | ||||||||||
| Title: | Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression. | ||||||||||
| Author: | Saxena, Ashish|Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K | ||||||||||
| PMID: | 23827854 | ||||||||||
| 15. | |||||||||||
| Journal: | Tumour Biol. 2013 Apr;34(2):683-93. | ||||||||||
| Title: | Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells. | ||||||||||
| Author: | Ding, Zhen-Yu|Liu, Gui-Hong|Olsson, Birgit|Sun, Xiao-Feng | ||||||||||
| PMID: | 23188704 | ||||||||||
| 16. | |||||||||||
| Journal: | BMC Cancer. 2014 Mar 6;14:160. | ||||||||||
| Title: | Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells. | ||||||||||
| Author: | Park, Ji-Won|Kim, Seung Cheol|Kim, Won Ki|Hong, Jun Pyu|Kim, Kyung-Hee|Yeo, Hyun Yang|Lee, Jae Yong|Kim, M Sun|Kim, Jong Heon|Yang, Se Young|Kim, Dae Yong|Oh, Jae Hwan|Cho, Jae Youl|Yoo, Byong Chul | ||||||||||
| PMID: | 24602180 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2014 Mar 25;9(3):e92966. | ||||||||||
| Title: | Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation. | ||||||||||
| Author: | Tsoli, Maria|Schweiger, Martina|Vanniasinghe, Anne S|Painter, Arran|Zechner, Rudolf|Clarke, Stephen|Robertson, Graham | ||||||||||
| PMID: | 24667661 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Cell Microenviron. 2014;1(5). | ||||||||||
| Title: | New insights into 4E-BP1-regulated translation in cancer progression and metastasis. | ||||||||||
| Author: | Wang, Jun|Ye, Qing|She, Qing-Bai | ||||||||||
| PMID: | 26005705 | ||||||||||
| 19. | |||||||||||
| Journal: | Nature. 2015 Jan 22;517(7535):497-500. | ||||||||||
| Title: | mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. | ||||||||||
| Author: | Faller, William J|Jackson, Thomas J|Knight, John Rp|Ridgway, Rachel A|Jamieson, Thomas|Karim, Saadia A|Jones, Carolyn|Radulescu, Sorina|Huels, David J|Myant, Kevin B|Dudek, Kate M|Casey, Helen A|Scopelliti, Alessandro|Cordero, Julia B|Vidal, Marcos|Pende, | ||||||||||
| PMID: | 25383520 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncogene. 2016 Jun 9;35(23):3004-15. | ||||||||||
| Title: | PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. | ||||||||||
| Author: | Fan, S-J|Snell, C|Turley, H|Li, J-L|McCormick, R|Perera, S M W|Heublein, S|Kazi, S|Azad, A|Wilson, C|Harris, A L|Goberdhan, D C I | ||||||||||
| PMID: | 26434594 | ||||||||||
| 21. | |||||||||||
| Journal: | Sci Signal. 2016 Oct 11;9(449):rs11. | ||||||||||
| Title: | Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks. | ||||||||||
| Author: | Simmons, Alan J|Scurrah, Cherie R|McKinley, Eliot T|Herring, Charles A|Irish, Jonathan M|Washington, M Kay|Coffey, Robert J|Lau, Ken S | ||||||||||
| PMID: | 27729552 | ||||||||||
| 22. | |||||||||||
| Journal: | J Cell Biol. 2017 Jun 5;216(6):1567-1577. | ||||||||||
| Title: | Oncogenic beta-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. | ||||||||||
| Author: | Riemer, Pamela|Rydenfelt, Mattias|Marks, Matthias|van Eunen, Karen|Thedieck, Kathrin|Herrmann, Bernhard G|Bluthgen, Nils|Sers, Christine|Morkel, Markus | ||||||||||
| PMID: | 28442534 | ||||||||||
| 23. | |||||||||||
| Journal: | Neoplasma. 2017;64(5):787-794. | ||||||||||
| Title: | Phosphorylated 4E-BP1 is associated with tumor progression and adverse prognosis in colorectal cancer. | ||||||||||
| Author: | Chen, Y|Wang, J|Fan, H|Xie, J|Xu, L|Zhou, B | ||||||||||
| PMID: | 28592131 | ||||||||||
| 24. | |||||||||||
| Journal: | J Gastrointest Cancer. 2017 Nov 7. pii: 10.1007/s12029-017-0024-9. | ||||||||||
| Title: | A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer. | ||||||||||
| Author: | Zhang, Tao|Ma, Yuanping|Fang, Jiansong|Liu, Chang|Chen, Liangrong | ||||||||||
| PMID: | 29110225 | ||||||||||
| 25. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Sep 10. pii: 1541-7786.MCR-18-0650. | ||||||||||
| Title: | Repurposing of mTOR Complex inhibitors Attenuates MCL-1 and sensitizes to PARP inhibition. | ||||||||||
| Author: | Mattoo, Abid R|Joun, Alex|Jessup, J Milburn | ||||||||||
| PMID: | 30201826 | ||||||||||