Literatures

Primary Site >> Colorectal Cancer

Gene >> EIF2AK3

1.
Journal:	J Clin Oncol. 2004 Nov 15;22(22):4456-62. Epub 2004 Oct 13.
Title:	Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer.
Author:	Rinehart, John\|Adjei, Alex A\|Lorusso, Patricia M\|Waterhouse, David\|Hecht, J Randolph\|Natale, Ronald B\|Hamid, Oday\|Varterasian, Mary\|Asbury, Peggy\|Kaldjian, Eric P\|Gulyas, Stephen\|Mitchell, David Y\|Herrera, Roman\|Sebolt-Leopold, Judith S\|Meyer, Mark B
PMID:	15483017

2.
Journal:	Carcinogenesis. 2006 Sep;27(9):1812-27. Epub 2006 Mar 7.
Title:	Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.
Author:	Guichard, Cecile\|Pedruzzi, Eric\|Fay, Michele\|Marie, Jean-Claude\|Braut-Boucher, Francoise\|Daniel, Fanny\|Grodet, Alain\|Gougerot-Pocidalo, Marie-Anne\|Chastre, Eric\|Kotelevets, Larissa\|Lizard, Gerard\|Vandewalle, Alain\|Driss, Fathi\|Ogier-Denis, Eric
PMID:	16524888

3.
Journal:	Mod Pathol. 2006 Oct;19(10):1302-9. Epub 2006 Jun 9.
Title:	Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer.
Author:	Lugli, Alessandro\|Zlobec, Inti\|Gunthert, Ursula\|Minoo, Parham\|Baker, Kristi\|Tornillo, Luigi\|Terracciano, Luigi\|Jass, Jeremy R
PMID:	16763611

4.
Journal:	Hum Pathol. 2006 Aug;37(8):1022-31. Epub 2006 May 26.
Title:	Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer-a tissue microarray-based approach.
Author:	Lugli, Alessandro\|Zlobec, Inti\|Minoo, Parham\|Baker, Kristi\|Tornillo, Luigi\|Terracciano, Luigi\|Jass, Jeremy R
PMID:	16867865

5.
Journal:	Cancer Res. 2007 Feb 1;67(3):1262-9.
Title:	Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
Author:	Little, Joy L\|Wheeler, Frances B\|Fels, Diane R\|Koumenis, Constantinos\|Kridel, Steven J
PMID:	17283163

6.
Journal:	J Surg Res. 2007 Oct;142(2):239-45.
Title:	A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model.
Author:	Fichera, Alessandro\|Little, Nathaniel\|Dougherty, Urszula\|Mustafi, Reba\|Cerda, Sonia\|Li, Yan Chun\|Delgado, Jorge\|Arora, Amrita\|Campbell, Lucas K\|Joseph, Loren\|Hart, John\|Noffsinger, Amy\|Bissonnette, Marc
PMID:	17574271

7.
Journal:	Cancer Res. 2008 May 1;68(9):3260-8.
Title:	Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival.
Author:	Ranganathan, Aparna C\|Ojha, Shishir\|Kourtidis, Antonis\|Conklin, Douglas S\|Aguirre-Ghiso, Julio A
PMID:	18451152

8.
Journal:	Oncol Rep. 2008 Jul;20(1):3-11.
Title:	Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
Author:	Georgieva, Milka\|Krasteva, Maria\|Angelova, Elka\|Ralchev, Krassimir\|Dimitrov, Valentin\|Bozhimirov, Stanislav\|Georgieva, Elena\|Berger, Martin R
PMID:	18575712

9.
Journal:	PLoS One. 2009 May 27;4(5):e5717.
Title:	Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.
Author:	Jaiswal, Bijay S\|Janakiraman, Vasantharajan\|Kljavin, Noelyn M\|Eastham-Anderson, Jeffrey\|Cupp, James E\|Liang, Yuxin\|Davis, David P\|Hoeflich, Klaus P\|Seshagiri, Somasekar
PMID:	19492075

10.
Journal:	BMC Cell Biol. 2009 Sep 15;10:64.
Title:	Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis.
Author:	Sequeira, Sharon J\|Wen, Huei Chi\|Avivar-Valderas, Alvaro\|Farias, Eduardo F\|Aguirre-Ghiso, Julio A
PMID:	19754954

11.
Journal:	J Cell Physiol. 2010 Jul;224(1):33-40.
Title:	Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
Author:	Kim, Ju-Young\|Hwang, Ji-Hwan\|Cha, Mi-Ran\|Yoon, Mi-Young\|Son, Eun-Soon\|Tomida, Akihiro\|Ko, Bosung\|Song, Si-Whan\|Shin-ya, Kazuo\|Hwang, Yong-il\|Park, Hae-Ryong
PMID:	20232300

12.
Journal:	Histopathology. 2010 Aug;57(2):233-43.
Title:	Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.
Author:	Karamitopoulou, Eva\|Lugli, Alessandro\|Panayiotides, Ioannis\|Karakitsos, Petros\|Peros, George\|Rallis, George\|Patsouris, Efstratios S\|Terracciano, Luigi\|Zlobec, Inti
PMID:	20716165

13.
Journal:	Int J Oncol. 2010 Sep;37(3):707-18.
Title:	Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles.
Author:	Minoo, P\|Zlobec, I\|Peterson, M\|Terracciano, L\|Lugli, A
PMID:	20664940

14.
Journal:	Cancer. 2010 Oct 1;116(19):4474-86.
Title:	Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Author:	Karamitopoulou, Eva\|Zlobec, Inti\|Koumarianou, Anna\|Patsouris, Efstratios S\|Peros, George\|Lugli, Alessandro
PMID:	20572035

15.
Journal:	Carcinogenesis. 2010 Apr;31(4):703-11.
Title:	The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta).
Author:	Yang, Hyun\|Park, Seong Hwan\|Choi, Hye Jin\|Moon, Yuseok
PMID:	20130018

16.
Journal:	Gastroenterology. 2010 Jan;138(1):221-30.
Title:	Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.
Author:	Stolfi, Carmine\|Sarra, Massimiliano\|Caruso, Roberta\|Fantini, Massimo Claudio\|Fina, Daniele\|Pellegrini, Roberto\|Palmieri, Giampiero\|Macdonald, Thomas T\|Pallone, Francesco\|Monteleone, Giovanni
PMID:	19737563

17.
Journal:	Cancer Res. 2011 Feb 1;71(3):1071-80.
Title:	Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17.
Author:	Van Schaeybroeck, Sandra\|Kyula, Joan N\|Fenton, Audrey\|Fenning, Catherine S\|Sasazuki, Takehiko\|Shirasawa, Senji\|Longley, Daniel B\|Johnston, Patrick G
PMID:	21148749

18.
Journal:	Pathology. 2011 Feb;43(2):133-7.
Title:	Loss of E-cadherin independently predicts the lymph node status in colorectal cancer.
Author:	Karamitopoulou, E\|Zlobec, I\|Patsouris, Es\|Peros, G\|Lugli, A
PMID:	21233674

19.
Journal:	PLoS One. 2011;6(5):e19628.
Title:	Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa.
Author:	Aviello, Gabriella\|Canadanovic-Brunet, Jasna M\|Milic, Natasa\|Capasso, Raffaele\|Fattorusso, Ernesto\|Taglialatela-Scafati, Orazio\|Fasolino, Ines\|Izzo, Angelo A\|Borrelli, Francesca
PMID:	21625488

20.
Journal:	Hum Pathol. 2011 Dec;42(12):1888-96.
Title:	Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Author:	Karamitopoulou, Eva\|Zlobec, Inti\|Panayiotides, Ioannis\|Patsouris, Efstratios S\|Peros, George\|Rallis, George\|Lapas, Christos\|Karakitsos, Petros\|Terracciano, Luigi M\|Lugli, Alessandro
PMID:	21664646

21.
Journal:	Oncol Res. 2011;19(7):311-21.
Title:	5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.
Author:	Mohapatra, Purusottam\|Preet, Ranjan\|Choudhuri, Maitrayee\|Choudhuri, Tathagata\|Kundu, Chanakya Nath
PMID:	21936401

22.
Journal:	Cancer Biol Ther. 2011 Nov 15;12(10):896-907.
Title:	Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis.
Author:	Tian, Maolin\|Wan, Yuanlian\|Tang, Jianqiang\|Li, Hui\|Yu, Ge\|Zhu, Jing\|Ji, Shiqi\|Guo, Hui\|Zhang, Nan\|Li, Weiren\|Gai, Junwei\|Wang, Lei\|Dai, Lifang\|Liu, Die\|Lei, Liandi\|Zhu, Shigong
PMID:	22052255

23.
Journal:	J Gastrointest Cancer. 2012 Sep;43(3):444-55.
Title:	Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.
Author:	Wang, Jayson\|Hollingshead, James\|El-Masry, Nabil\|Horncastle, Donna\|Talbot, Ian\|Tomlinson, Ian\|Alison, Malcolm R\|El-Bahrawy, Mona
PMID:	21989899

24.
Journal:	Biochim Biophys Acta. 2012 Nov;1822(11):1762-72.
Title:	DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines.
Author:	Fasano, Elena\|Serini, Simona\|Piccioni, Elisabetta\|Toesca, Amelia\|Monego, Giovanni\|Cittadini, Achille R\|Ranelletti, Franco O\|Calviello, Gabriella
PMID:	22898250

25.
Journal:	Int J Oncol. 2012 Aug;41(2):583-8.
Title:	Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases.
Author:	Jin, Ketao\|Lan, Huanrong\|Cao, Feilin\|Han, Na\|Xu, Zhenzhen\|Li, Guangliang\|He, Kuifeng\|Teng, Lisong
PMID:	22581265

26.
Journal:	Mol Cancer Ther. 2012 Apr;11(4):930-41.
Title:	CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity.
Author:	James, Joyce\|Ruggeri, Bruce\|Armstrong, Robert C\|Rowbottom, Martin W\|Jones-Bolin, Susan\|Gunawardane, Ruwanthi N\|Dobrzanski, Pawel\|Gardner, Michael F\|Zhao, Hugh\|Cramer, Merryl D\|Hunter, Kathryn\|Nepomuceno, Ronald R\|Cheng, Mangeng\|Gitnick, Dana\|Yazdanian, Me
PMID:	22319199

27.
Journal:	Biochem J. 2012 Apr 15;443(2):379-86.
Title:	The non-steroidal anti-inflammatory drug indomethacin activates the eIF2alpha kinase PKR, causing a translational block in human colorectal cancer cells.
Author:	Brunelli, Claudia\|Amici, Carla\|Angelini, Mara\|Fracassi, Chiara\|Belardo, Giuseppe\|Santoro, M Gabriella
PMID:	22268531

28.
Journal:	World J Surg Oncol. 2012 Feb 29;10:47.
Title:	ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics.
Author:	Levidou, Georgia\|Saetta, Angelica A\|Gigelou, Fanie\|Karlou, Maria\|Papanastasiou, Polyanthi\|Stamatelli, Angeliki\|Kavantzas, Nikolaos\|Michalopoulos, Nikolaos V\|Agrogiannis, George\|Patsouris, Efstratios\|Korkolopoulou, Penelope
PMID:	22376079

29.
Journal:	Cell Death Dis. 2013 Oct 10;4:e851.
Title:	Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Author:	Matassa, D S\|Amoroso, M R\|Agliarulo, I\|Maddalena, F\|Sisinni, L\|Paladino, S\|Romano, S\|Romano, M F\|Sagar, V\|Loreni, F\|Landriscina, M\|Esposito, F
PMID:	24113185

30.
Journal:	Cancer Prev Res (Phila). 2013 Dec;6(12):1337-47.
Title:	The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid.
Author:	Zhang, Xiaobo\|Lee, Seong-Ho\|Min, Kyung-Won\|McEntee, Michael F\|Jeong, Jin Boo\|Li, Qingwang\|Baek, Seung Joon
PMID:	24104354

31.
Journal:	Med Oncol. 2013 Dec;30(4):724.
Title:	High level of p37delta-mRNA relative to p110delta-mRNA in neuroblastoma tumors correlates with poor patient survival.
Author:	Fransson, Susanne\|Ejeskar, Katarina
PMID:	24026661

32.
Journal:	Cancer Chemother Pharmacol. 2013 Oct;72(4):767-75.
Title:	Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells.
Author:	Zhang, Guanzhong\|Xie, Xiaodong\|Liu, Tianyi\|Yang, Jihua\|Jiao, Shunchang
PMID:	23959460

33.
Journal:	Oncol Rep. 2013 Apr;29(4):1365-70.
Title:	20-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells.
Author:	Zhang, Rui\|Chung, Young\|Kim, Hee Sun\|Kim, Dong Hyun\|Kim, Hye Sun\|Chang, Weon Young\|Hyun, Jin Won
PMID:	23381572

34.
Journal:	Invest New Drugs. 2013 Feb;31(1):1-13.
Title:	Circulating vascular endothelial growth factor receptor 2/pAkt-positive cells as a functional pharmacodynamic marker in metastatic colorectal cancers treated with antiangiogenic agent.
Author:	Shin, Sang Joon\|Hwang, Jee Won\|Ahn, Joong Bae\|Rha, Sun Young\|Roh, Jae Kyung\|Chung, Hyun Cheol
PMID:	22539090

35.
Journal:	Mol Carcinog. 2013 Jan;52(1):1-17.
Title:	Cladosporol a stimulates G1-phase arrest of the cell cycle by up-regulation of p21(waf1/cip1) expression in human colon carcinoma HT-29 cells.
Author:	Zurlo, Diana\|Leone, Cinzia\|Assante, Gemma\|Salzano, Salvatore\|Renzone, Giovanni\|Scaloni, Andrea\|Foresta, Caterina\|Colantuoni, Vittorio\|Lupo, Angelo
PMID:	22025467

36.
Journal:	Mol Pharmacol. 2014 Mar;85(3):451-9.
Title:	Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.
Author:	Trondl, Robert\|Flocke, Lea S\|Kowol, Christian R\|Heffeter, Petra\|Jungwirth, Ute\|Mair, Georg E\|Steinborn, Ralf\|Enyedy, Eva A\|Jakupec, Michael A\|Berger, Walter\|Keppler, Bernhard K
PMID:	24378333

37.
Journal:	Biochem Biophys Res Commun. 2014 Mar 7;445(2):320-6.
Title:	Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells.
Author:	Liu, Jia\|Edagawa, Makoto\|Goshima, Hiroto\|Inoue, Makoto\|Yagita, Hideo\|Liu, Zhonghui\|Kitajima, Shigetaka
PMID:	24530917

38.
Journal:	J Biol Chem. 2014 Aug 1;289(31):21544-61.
Title:	Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-re
Author:	Edagawa, Makoto\|Kawauchi, Junya\|Hirata, Manabu\|Goshima, Hiroto\|Inoue, Makoto\|Okamoto, Tatsuro\|Murakami, Akira\|Maehara, Yoshihiko\|Kitajima, Shigetaka
PMID:	24939851

39.
Journal:	Biochim Biophys Acta. 2014 Sep;1841(9):1308-17.
Title:	DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.
Author:	Skender, Belma\|Hofmanova, Jirina\|Slavik, Josef\|Jelinkova, Iva\|Machala, Miroslav\|Moyer, Mary Pat\|Kozubik, Alois\|Hyrslova Vaculova, Alena
PMID:	24953781

40.
Journal:	Mol Cancer Ther. 2014 Dec;13(12):2876-85.
Title:	Therapeutic silencing of KRAS using systemically delivered siRNAs.
Author:	Pecot, Chad V\|Wu, Sherry Y\|Bellister, Seth\|Filant, Justyna\|Rupaimoole, Rajesha\|Hisamatsu, Takeshi\|Bhattacharya, Rajat\|Maharaj, Anshumaan\|Azam, Salma\|Rodriguez-Aguayo, Cristian\|Nagaraja, Archana S\|Morelli, Maria Pia\|Gharpure, Kshipra M\|Waugh, Trent A\|Gonza
PMID:	25281617

41.
Journal:	PLoS One. 2015 Dec 17;10(12):e0144708.
Title:	Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author:	Briffa, Romina\|Um, Inhwa\|Faratian, Dana\|Zhou, Ying\|Turnbull, Arran K\|Langdon, Simon P\|Harrison, David J
PMID:	26678268

42.
Journal:	Anticancer Drugs. 2015 Apr;26(4):371-8.
Title:	Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
Author:	Gamba, Sebastian\|Camaj, Peter\|Heinemann, Volker\|Laubender, Rudiger P\|Wang, Yan\|Zhao, Yue\|Stintzing, Sebastian\|Giessen, Clemens\|Boeck, Stefan\|Haertl, Christoph\|Bruns, Christiane J\|Modest, Dominik P
PMID:	25514114

43.
Journal:	Sci Rep. 2015 Nov 30;5:17348.
Title:	Mulberry fruit prevents LPS-induced NF-kappaB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice.
Author:	Qian, Zhengjiang\|Wu, Zhiqin\|Huang, Lian\|Qiu, Huiling\|Wang, Liyan\|Li, Li\|Yao, Lijun\|Kang, Kang\|Qu, Junle\|Wu, Yonghou\|Luo, Jun\|Liu, Johnson J\|Yang, Yi\|Yang, Wancai\|Gou, Deming
PMID:	26615818

44.
Journal:	Oncotarget. 2015 Nov 17;6(36):39247-61.
Title:	Depletion of the thiol oxidoreductase ERp57 in tumor cells inhibits proliferation and increases sensitivity to ionizing radiation and chemotherapeutics.
Author:	Hussmann, Melanie\|Janke, Kirsten\|Kranz, Philip\|Neumann, Fabian\|Mersch, Evgenija\|Baumann, Melanie\|Goepelt, Kirsten\|Brockmeier, Ulf\|Metzen, Eric
PMID:	26513173

45.
Journal:	BMC Cancer. 2015 Apr 17;15:301.
Title:	Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Author:	Chen, Kuen-Feng\|Yen, Chueh-Chuan\|Lin, Jen-Kou\|Chen, Wei-Shone\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Lan, Yuan-Tzu\|Lin, Chun-Chi\|Yu, Hui-Chuan\|Hsu, Hui-Mei\|Lin, Wen-Ling\|Teng, Hao-Wei
PMID:	25896895

46.
Journal:	Oncol Rep. 2015 Jun;33(6):2761-70.
Title:	Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells.
Author:	Coker-Gurkan, Ajda\|Arisan, Elif Damla\|Obakan, Pinar\|Akalin, Kubra\|Ozbey, Utku\|Palavan-Unsal, Narcin
PMID:	25901510

47.
Journal:	Br J Cancer. 2015 Jan 6;112(1):24-31.
Title:	A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours.
Author:	Wilky, B A\|Rudek, M A\|Ahmed, S\|Laheru, D A\|Cosgrove, D\|Donehower, R C\|Nelkin, B\|Ball, D\|Doyle, L A\|Chen, H\|Ye, X\|Bigley, G\|Womack, C\|Azad, N S
PMID:	25268371

48.
Journal:	Cancer Res Treat. 2016 Jan;48(1):355-64.
Title:	Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells.
Author:	Kang, Mi Hyun\|Moon, Sung Ung\|Sung, Ji Hea\|Kim, Jin Won\|Lee, Keun Wook\|Lee, Hye Seung\|Lee, Jong Seok\|Kim, Jee Hyun
PMID:	25761479

49.
Journal:	Hypoxia (Auckl). 2016 Dec 8;4:163-174.
Title:	Combination effects of sorafenib with PI3K inhibitors under hypoxia in colorectal cancer.
Author:	Bhatia, Dimple R\|Thiagarajan, Padma
PMID:	27995152

50.
Journal:	Oncotarget. 2016 Nov 1;7(44):71400-71416.
Title:	STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways.
Author:	Chen, Bing\|Zeng, Xiao\|He, Yu\|Wang, Xixi\|Liang, Ziwei\|Liu, Jingjing\|Zhang, Peng\|Zhu, Hongxia\|Xu, Ningzhi\|Liang, Shufang
PMID:	27662663

51.
Journal:	Oncol Rep. 2016 Oct;36(4):2268-74.
Title:	Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells.
Author:	Ruwan Kumara, Madduma Hewage Susara\|Piao, Mei Jing\|Kang, Kyoung Ah\|Ryu, Yea Seong\|Park, Jeong Eon\|Shilnikova, Kristina\|Jo, Jin Oh\|Mok, Young Sun\|Shin, Jennifer H\|Park, Yeonsoo\|Kim, Seong Bong\|Yoo, Suk Jae\|Hyun, Jin Won
PMID:	27573888

52.
Journal:	Oncotarget. 2016 Jul 5;7(27):41432-41444.
Title:	Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment.
Author:	Banerjee, Aditi\|Ahmed, Hafiz\|Yang, Peixin\|Czinn, Steven J\|Blanchard, Thomas G
PMID:	27166181

53.
Journal:	PLoS One. 2016 Apr 14;11(4):e0153627.
Title:	Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells.
Author:	Lai, Ming-Chih\|Chang, Chiao-May\|Sun, H Sunny
PMID:	27078027

54.
Journal:	Hum Pathol. 2016 Aug;54:37-46.
Title:	Localization of active, dually phosphorylated extracellular signal-regulated kinase 1 and 2 in colorectal cancer with or without activating BRAF and KRAS mutations.
Author:	Holck, Susanne\|Bonde, Jesper\|Pedersen, Helle\|Petersen, Anja Alex\|Chaube, Amita\|Nielsen, Hans Jorgen\|Larsson, Lars-Inge
PMID:	27036313

55.
Journal:	Invest New Drugs. 2016 Jun;34(3):261-8.
Title:	Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines.
Author:	Flocke, Lea S\|Trondl, Robert\|Jakupec, Michael A\|Keppler, Bernhard K
PMID:	26988975

56.
Journal:	Cell Death Dis. 2016 Feb 25;7:e2108.
Title:	The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells.
Author:	Colangelo, T\|Polcaro, G\|Ziccardi, P\|Muccillo, L\|Galgani, M\|Pucci, B\|Milone, M Rita\|Budillon, A\|Santopaolo, M\|Mazzoccoli, G\|Matarese, G\|Sabatino, L\|Colantuoni, V
PMID:	26913599

57.
Journal:	Tumour Biol. 2016 May;37(5):6501-10.
Title:	FAM172A is a tumor suppressor in colorectal carcinoma.
Author:	Cui, Chunhui\|Ye, Lili\|Huang, Zonghai\|Huang, Shuxin\|Liu, Hao\|Yu, Jinlong
PMID:	26637224

58.
Journal:	J Cell Biochem. 2016 May;117(5):1078-91.
Title:	TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways.
Author:	Lee, Dae-Hee\|Sung, Ki Sa\|Guo, Zong Sheng\|Kwon, William Taehyung\|Bartlett, David L\|Oh, Sang Cheul\|Kwon, Yong Tae\|Lee, Yong J
PMID:	26212606

59.
Journal:	Oncotarget. 2017 Aug 2;8(59):99451-99469.
Title:	Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species.
Author:	Roberts, Jane L\|Poklepovic, Andrew\|Booth, Laurence
PMID:	29245915

60.
Journal:	Cell Death Dis. 2017 Aug 10;8(8):e2986.
Title:	PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR).
Author:	Kranz, Philip\|Neumann, Fabian\|Wolf, Alexandra\|Classen, Fabian\|Pompsch, Mosche\|Ocklenburg, Tobias\|Baumann, Jennifer\|Janke, Kirsten\|Baumann, Melanie\|Goepelt, Kirsten\|Riffkin, Helena\|Metzen, Eric\|Brockmeier, Ulf
PMID:	28796255

61.
Journal:	Dev Reprod. 2017 Jun;21(2):139-150.
Title:	Metformin Synergistically Potentiates the Antitumor Effects of Imatinib in Colorectal Cancer Cells.
Author:	Lee, Jaeryun\|Park, Deokbae\|Lee, Youngki
PMID:	28785735

62.
Journal:	Cell Death Dis. 2017 Jul 27;8(7):e2957.
Title:	Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress.
Author:	Xia, Dan\|Ji, Wanli\|Xu, Chentong\|Lin, Xin\|Wang, Xiaokun\|Xia, Yan\|Lv, Ping\|Song, Quansheng\|Ma, Dalong\|Chen, Yingyu
PMID:	28749466

63.
Journal:	Anticancer Res. 2017 Jun;37(6):2975-2984.
Title:	Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Author:	Yun, Seungpil\|Han, Yong-Seok\|Lee, Jun Hee\|Kim, Sangmin\|Lee, Sang Hun
PMID:	28551635

64.
Journal:	Am J Cancer Res. 2017 Feb 1;7(2):275-288. eCollection 2017.
Title:	Curcumin derivative WZ35 efficiently suppresses colon cancer progression through inducing ROS production and ER stress-dependent apoptosis.
Author:	Zhang, Junru\|Feng, Zhiguo\|Wang, Chunhua\|Zhou, Huiping\|Liu, Weidong\|Kanchana, Karvannan\|Dai, Xuanxuan\|Zou, Peng\|Gu, Junlian\|Cai, Lu\|Liang, Guang
PMID:	28337376

65.
Journal:	Cell Death Dis. 2017 Mar 16;8(3):e2681.
Title:	Smad7 knockdown activates protein kinase RNA-associated eIF2alpha pathway leading to colon cancer cell death.
Author:	De Simone, Veronica\|Bevivino, Gerolamo\|Sedda, Silvia\|Izzo, Roberta\|Laudisi, Federica\|Dinallo, Vincenzo\|Franze, Eleonora\|Colantoni, Alfredo\|Ortenzi, Angela\|Salvatori, Silvia\|Rossi, Piero\|Sica, Giuseppe S\|Fantini, Massimo C\|Stolfi, Carmine\|Monteleone, Giova
PMID:	28300830

66.
Journal:	Arch Pharm Res. 2017 May;40(5):579-591.
Title:	TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy.
Author:	Zhang, Dandan\|Gao, Cuixia\|Li, Ruyi\|Zhang, Lin\|Tian, Jingkui
PMID:	28211011

67.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2017 Mar 1;49(3):228-237.
Title:	Salubrinal protects against Clostridium difficile toxin B-induced CT26 cell death.
Author:	Chen, Shuyi\|Sun, Chunli\|Gu, Huawei\|Wang, Haiying\|Li, Shan\|Ma, Yi\|Wang, Jufang
PMID:	28119311

68.
Journal:	Biomed Pharmacother. 2017 Apr;88:151-161.
Title:	3',5-dihydroxy-3,4',7-trimethoxyflavone-induces ER-stress-associated HCT-116 programmed cell death via redox signaling.
Author:	Singh, Mahendra Pal\|Han, Jaehong\|Kang, Sun Chul
PMID:	28103509

69.
Journal:	Oncotarget. 2017 Jan 3;8(1):988-998.
Title:	Preclinical study of cinobufagin as a promising anti-colorectal cancer agent.
Author:	Lu, Xing-Sheng\|Qiao, Yin-Biao\|Li, Ya\|Yang, Bo\|Chen, Min-Bin\|Xing, Chun-Gen
PMID:	27894091

70.
Journal:	Oncogene. 2017 Jul 27;36(30):4336-4348.
Title:	TGFbeta engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.
Author:	Principe, D R\|Diaz, A M\|Torres, C\|Mangan, R J\|DeCant, B\|McKinney, R\|Tsao, M-S\|Lowy, A\|Munshi, H G\|Jung, B\|Grippo, P J
PMID:	28368414

71.
Journal:	Med Sci Monit. 2018 Sep 10;24:6331-6339.
Title:	Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells.
Author:	Cheng, Chunsheng\|Dong, Weiguo
PMID:	30199885

72.
Journal:	Expert Rev Gastroenterol Hepatol. 2018 Sep 26:1-18.
Title:	An update on dietary consideration in inflammatory bowel disease: anthocyanins and more.
Author:	Farzaei, Mohammad Hosein\|El-Senduny, Fardous F\|Momtaz, Saeideh\|Parvizi, Fatemeh\|Iranpanah, Amin\|Tewari, Devesh\|Naseri, Rozita\|Abdolghaffari, Amir Hossein\|Rezaei, Nima
PMID:	30136591

73.
Journal:	Oncol Lett. 2018 Sep;16(3):3901-3906.
Title:	Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways.
Author:	Tan, Bo\|Jia, Renfeng\|Wang, Gang\|Yang, Jinhui
PMID:	30128005

74.
Journal:	PLoS One. 2018 Aug 17;13(8):e0200836.
Title:	Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.
Author:	Pal, Rekha\|Wei, Ning\|Song, Nan\|Wu, Shaoyu\|Kim, Rim S\|Wang, Ying\|Gavin, Patrick G\|Lucas, Peter C\|Srinivasan, Ashok\|Allegra, Carmen J\|Jacobs, Samuel A\|Paik, Soonmyung\|Schmitz, John C\|Pogue-Geile, Katherine L
PMID:	30118499

75.
Journal:	Biomol Ther (Seoul). 2018 Jun 21. pii: biomolther.2018.047.
Title:	Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways.
Author:	Han, Xia\|Kang, Kyoung Ah\|Piao, Mei Jing\|Zhen, Ao Xuan\|Hyun, Yu Jae\|Kim, Hyun Min\|Ryu, Yea Seong\|Hyun, Jin Won
PMID:	29925224

76.
Journal:	Mol Carcinog. 2018 Oct;57(10):1383-1395.
Title:	A452, an HDAC6-selective inhibitor, synergistically enhances the anticancer activity of chemotherapeutic agents in colorectal cancer cells.
Author:	Won, Hye-Rim\|Ryu, Hyun-Wook\|Shin, Dong-Hee\|Yeon, Soo-Keun\|Lee, Dong Hoon\|Kwon, So Hee
PMID:	29917295

77.
Journal:	Oncol Rep. 2018 Aug;40(2):704-714.
Title:	Fibroblast growth factor 18 promotes the growth, migration and invasion of MDAMB231 cells.
Author:	Yu, Ziyi\|Lou, Longquan\|Zhao, Yi
PMID:	29901199

78.
Journal:	Chem Biol Interact. 2018 Aug 1;291:16-28.
Title:	Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer.
Author:	Sharma, Sharada H\|Rajamanickam, Vinothkumar\|Nagarajan, Sangeetha
PMID:	29879413

79.
Journal:	Nat Mater. 2018 Apr;17(4):361-368.
Title:	Quantitative self-assembly prediction yields targeted nanomedicines.
Author:	Shamay, Yosi\|Shah, Janki\|Isik, Mehtap\|Mizrachi, Aviram\|Leibold, Josef\|Tschaharganeh, Darjus F\|Roxbury, Daniel\|Budhathoki-Uprety, Januka\|Nawaly, Karla\|Sugarman, James L\|Baut, Emily\|Neiman, Michelle R\|Dacek, Megan\|Ganesh, Kripa S\|Johnson, Darren C\|Sridharan
PMID:	29403054

80.
Journal:	Int J Mol Med. 2018 Apr;41(4):1887-1898.
Title:	Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway.
Author:	Wang, Qiuyu\|Wang, Peng\|Xiao, Zhigang
PMID:	29393371

81.
Journal:	Mol Med Rep. 2018 Jan;17(1):542-548.
Title:	GOLPH3 expression promotes the resistance of HT29 cells to 5fluorouracil by activating multiple signaling pathways.
Author:	Wang, Ming-Zhen\|Qiu, Cheng-Zhi\|Yu, Wai-Shi\|Guo, Yan-Ta\|Wang, Chun-Xiao\|Chen, Zhi-Xiong
PMID:	29115442

82.
Journal:	Biochem Cell Biol. 2018 Jun;96(3):332-341.
Title:	Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response.
Author:	Liang, Guodong\|Fang, Xuedong\|Yang, Yubo\|Song, Yan
PMID:	29024602