Primary Site >> Colorectal Cancer
Gene >> EIF2AK2
| 1. | |||||||||||
| Journal: | Mol Cell Biol. 1999 Feb;19(2):1116-25. | ||||||||||
| Title: | Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18. | ||||||||||
| Author: | Kumar, K U|Srivastava, S P|Kaufman, R J | ||||||||||
| PMID: | 9891046 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2002 Dec 12;21(57):8741-8. | ||||||||||
| Title: | Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR. | ||||||||||
| Author: | Kim, Steve H|Gunnery, Shobha|Choe, Jin K|Mathews, Michael B | ||||||||||
| PMID: | 12483527 | ||||||||||
| 3. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2005 Sep;35(9):545-50. | ||||||||||
| Title: | Expression of double-stranded RNA-activated protein kinase (PKR) and its prognostic significance in lymph node negative rectal cancer. | ||||||||||
| Author: | Kwon, Hyuk-Chan|Moon, Chang Hoon|Kim, Sung-Hyun|Choi, Hong-Jo|Lee, Hyung-Sik|Roh, Mee Sook|Hwang, Tae-Ho|Kim, Jae-Seok|Kim, Hyo-Jin | ||||||||||
| PMID: | 16148023 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Gene Ther. 2008 Sep;15(9):616-24. | ||||||||||
| Title: | JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase. | ||||||||||
| Author: | Hu, W|Hofstetter, W|Guo, W|Li, H|Pataer, A|Peng, H H|Guo, Z S|Bartlett, D L|Lin, A|Swisher, S G|Fang, B | ||||||||||
| PMID: | 18535619 | ||||||||||
| 5. | |||||||||||
| Journal: | J Natl Cancer Inst. 2008 Sep 3;100(17):1233-46. | ||||||||||
| Title: | Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide. | ||||||||||
| Author: | Trisciuoglio, Daniela|Uranchimeg, Badarch|Cardellina, John H|Meragelman, Tamara L|Matsunaga, Shigeki|Fusetani, Nobuhiru|Del Bufalo, Donatella|Shoemaker, Robert H|Melillo, Giovanni | ||||||||||
| PMID: | 18728285 | ||||||||||
| 6. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2009 May 12;106(19):7852-7. | ||||||||||
| Title: | PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53. | ||||||||||
| Author: | Yoon, Cheol-Hee|Lee, Eun-Soo|Lim, Dae-Seog|Bae, Yong-Soo | ||||||||||
| PMID: | 19416861 | ||||||||||
| 7. | |||||||||||
| Journal: | Gene Ther. 2009 Jul;16(7):905-15. | ||||||||||
| Title: | Herpes simplex virus delivery to orthotopic rectal carcinoma results in an efficient and selective antitumor effect. | ||||||||||
| Author: | Kolodkin-Gal, D|Edden, Y|Hartshtark, Z|Ilan, L|Khalaileh, A|Pikarsky, A J|Pikarsky, E|Rabkin, S D|Panet, A|Zamir, G | ||||||||||
| PMID: | 19440231 | ||||||||||
| 8. | |||||||||||
| Journal: | Carcinogenesis. 2010 Apr;31(4):703-11. | ||||||||||
| Title: | The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta). | ||||||||||
| Author: | Yang, Hyun|Park, Seong Hwan|Choi, Hye Jin|Moon, Yuseok | ||||||||||
| PMID: | 20130018 | ||||||||||
| 9. | |||||||||||
| Journal: | Biochem J. 2012 Apr 15;443(2):379-86. | ||||||||||
| Title: | The non-steroidal anti-inflammatory drug indomethacin activates the eIF2alpha kinase PKR, causing a translational block in human colorectal cancer cells. | ||||||||||
| Author: | Brunelli, Claudia|Amici, Carla|Angelini, Mara|Fracassi, Chiara|Belardo, Giuseppe|Santoro, M Gabriella | ||||||||||
| PMID: | 22268531 | ||||||||||
| 10. | |||||||||||
| Journal: | Drug Des Devel Ther. 2013 Oct 29;7:1301-13. | ||||||||||
| Title: | Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNalpha triggering apoptosis, autophagy and senescence. | ||||||||||
| Author: | Marchal, Juan Antonio|Carrasco, Esther|Ramirez, Alberto|Jimenez, Gema|Olmedo, Carmen|Peran, Macarena|Agil, Ahmad|Conejo-Garcia, Ana|Cruz-Lopez, Olga|Campos, Joaquin Maria|Garcia, Maria Angel | ||||||||||
| PMID: | 24194639 | ||||||||||
| 11. | |||||||||||
| Journal: | Cell Microbiol. 2015 Sep;17(9):1391-404. | ||||||||||
| Title: | Inhibition of viral protein translation by indomethacin in vesicular stomatitis virus infection: role of eIF2alpha kinase PKR. | ||||||||||
| Author: | Amici, Carla|La Frazia, Simone|Brunelli, Claudia|Balsamo, Mirna|Angelini, Mara|Santoro, M Gabriella | ||||||||||
| PMID: | 25856684 | ||||||||||
| 12. | |||||||||||
| Journal: | DNA Cell Biol. 2015 Aug;34(8):541-9. | ||||||||||
| Title: | The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways. | ||||||||||
| Author: | Hernandez, Jonathan M|Elahi, Abul|Clark, Whalen|Humphries, Leigh Ann|Wang, Jian|Achille, Alex|Seto, Ed|Shibata, David | ||||||||||
| PMID: | 26061044 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Death Dis. 2017 Mar 16;8(3):e2681. | ||||||||||
| Title: | Smad7 knockdown activates protein kinase RNA-associated eIF2alpha pathway leading to colon cancer cell death. | ||||||||||
| Author: | De Simone, Veronica|Bevivino, Gerolamo|Sedda, Silvia|Izzo, Roberta|Laudisi, Federica|Dinallo, Vincenzo|Franze, Eleonora|Colantoni, Alfredo|Ortenzi, Angela|Salvatori, Silvia|Rossi, Piero|Sica, Giuseppe S|Fantini, Massimo C|Stolfi, Carmine|Monteleone, Giova | ||||||||||
| PMID: | 28300830 | ||||||||||
| 14. | |||||||||||
| Journal: | World J Stem Cells. 2017 May 26;9(5):77-88. | ||||||||||
| Title: | Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue. | ||||||||||
| Author: | Ishikawa, Tetsuya | ||||||||||
| PMID: | 28596815 | ||||||||||
| 15. | |||||||||||
| Journal: | Elife. 2017 Aug 18;6. | ||||||||||
| Title: | Blockade of the LRP16-PKR-NF-kappaB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy. | ||||||||||
| Author: | Li, Xiaolei|Wu, Zhiqiang|An, Xiaojing|Mei, Qian|Bai, Miaomiao|Hanski, Leena|Li, Xiang|Ahola, Tero|Han, Weidong | ||||||||||
| PMID: | 28820388 | ||||||||||
| 16. | |||||||||||
| Journal: | Anticancer Res. 2018 Oct;38(10):5791-5798. | ||||||||||
| Title: | Kisspeptin Inhibits Colorectal Cancer Cell Invasiveness by Activating PKR and PP2A. | ||||||||||
| Author: | Kim, Jeong Nam|Kim, Tae Hun|Yoon, Ji-Hye|Cho, Sung-Gook | ||||||||||
| PMID: | 30275201 | ||||||||||