Primary Site >> Liver Cancer
Gene >> EHMT2
| 1. | |||||||||||
| Journal: | Hepatol Res. 2007 Nov;37(11):974-83. | ||||||||||
| Title: | Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas. | ||||||||||
| Author: | Kondo, Yutaka|Shen, Lanlan|Suzuki, Seiji|Kurokawa, Tsuyoshi|Masuko, Kazuo|Tanaka, Yasuhito|Kato, Hideaki|Mizuno, Yoshiki|Yokoe, Masamichi|Sugauchi, Fuminaka|Hirashima, Noboru|Orito, Etsuro|Osada, Hirotaka|Ueda, Ryuzo|Guo, Yi|Chen, Xinli|Issa, Jean-Pierre | ||||||||||
| PMID: | 17584191 | ||||||||||
| 2. | |||||||||||
| Journal: | J Appl Toxicol. 2013 Sep;33(9):951-8. | ||||||||||
| Title: | Long-term arsenic exposure induces histone H3 Lys9 dimethylation without altering DNA methylation in the promoter region of p16(INK4a) and down-regulates its expression in the liver of mice. | ||||||||||
| Author: | Suzuki, Takehiro|Nohara, Keiko | ||||||||||
| PMID: | 22733434 | ||||||||||
| 3. | |||||||||||
| Journal: | Hum Mol Genet. 2013 Oct 15;22(20):4233-8. | ||||||||||
| Title: | A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. | ||||||||||
| Author: | Kim, Yoon Jun|Kim, Hwi Young|Lee, Jeong-Hoon|Yu, Su Jong|Yoon, Jung-Hwan|Lee, Hyo-Suk|Kim, Chung Yong|Cheong, Jae Youn|Cho, Sung Won|Park, Neung Hwa|Park, Byung Lae|Namgoong, Seok|Kim, Lyoung Hyo|Cheong, Hyun Sub|Shin, Hyoung Doo | ||||||||||
| PMID: | 23760081 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2014 Apr 15;7(5):2496-507. eCollection 2014. | ||||||||||
| Title: | Histone-modifying genes as biomarkers in hepatocellular carcinoma. | ||||||||||
| Author: | Hung, Shih-Ya|Lin, Hui-Hua|Yeh, Kun-Tu|Chang, Jan-Gowth | ||||||||||
| PMID: | 24966962 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cells. 2015 Jun;38(6):528-34. | ||||||||||
| Title: | The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1alpha Stability and Angiogenesis. | ||||||||||
| Author: | Oh, Su Young|Seok, Ji Yoon|Choi, Young Sun|Lee, Sung Hee|Bae, Jong-Sup|Lee, You Mie | ||||||||||
| PMID: | 26013382 | ||||||||||
| 6. | |||||||||||
| Journal: | J Med Virol. 2016 Mar;88(3):371-9. | ||||||||||
| Title: | Host genetic variants influencing the clinical course of hepatitis B virus infection. | ||||||||||
| Author: | Matsuura, Kentaro|Isogawa, Masanori|Tanaka, Yasuhito | ||||||||||
| PMID: | 26255971 | ||||||||||
| 7. | |||||||||||
| Journal: | Medicine (Baltimore). 2016 Jan;95(2):e2493. | ||||||||||
| Title: | Association of Histone Methyltransferase G9a and Overall Survival After Liver Resection of Patients With Hepatocellular Carcinoma With a Median Observation of 40 Months. | ||||||||||
| Author: | Bai, Kai|Cao, Yi|Huang, Chao|Chen, Jianwei|Zhang, Xiaojin|Jiang, Yi | ||||||||||
| PMID: | 26765460 | ||||||||||
| 8. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2016 Aug 1;304:42-7. | ||||||||||
| Title: | Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a. | ||||||||||
| Author: | Zhang, Xi|Wu, Jianguo|Choiniere, Jonathan|Yang, Zhihong|Huang, Yi|Bennett, Jason|Wang, Li | ||||||||||
| PMID: | 27217333 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 28;8(13):21315-21326. | ||||||||||
| Title: | Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma. | ||||||||||
| Author: | Yokoyama, Masayuki|Chiba, Tetsuhiro|Zen, Yoh|Oshima, Motohiko|Kusakabe, Yuko|Noguchi, Yoshiko|Yuki, Kaori|Koide, Shuhei|Tara, Shiro|Saraya, Atsunori|Aoyama, Kazumasa|Mimura, Naoya|Miyagi, Satoru|Inoue, Masanori|Wakamatsu, Toru|Saito, Tomoko|Ogasawara, Sad | ||||||||||
| PMID: | 28423509 | ||||||||||
| 10. | |||||||||||
| Journal: | J Hepatol. 2017 Oct;67(4):758-769. | ||||||||||
| Title: | Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3. | ||||||||||
| Author: | Wei, Lai|Chiu, David Kung-Chun|Tsang, Felice Ho-Ching|Law, Cheuk-Ting|Cheng, Carol Lai-Hung|Au, Sandy Leung-Kuen|Lee, Joyce Man-Fong|Wong, Carmen Chak-Lui|Ng, Irene Oi-Lin|Wong, Chun-Ming | ||||||||||
| PMID: | 28532996 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 28;8(38):63187-63207. | ||||||||||
| Title: | Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors. | ||||||||||
| Author: | Zang, Lanlan|Kondengaden, Shukkoor M|Zhang, Qing|Li, Xiaobo|Sigalapalli, Dilep K|Kondengadan, Shameer M|Huang, Kenneth|Li, Keqin Kathy|Li, Shanshan|Xiao, Zhongying|Wen, Liuqing|Zhu, Hailiang|Babu, Bathini N|Wang, Lijuan|Che, Fengyuan|Wang, Peng George | ||||||||||
| PMID: | 28968981 | ||||||||||
| 12. | |||||||||||
| Journal: | Genes Immun. 2017 Dec 14. pii: 10.1038/s41435-017-0004-x. | ||||||||||
| Title: | Identification of additional EHMT2 variant associated with the risk of chronic hepatitis B by GWAS follow-up study. | ||||||||||
| Author: | Shin, Joong-Gon|Cheong, Hyun Sub|Kim, Jason Yongha|Lee, Jeong-Hoon|Yu, Su Jong|Yoon, Jung-Hwan|Cheong, Jae Youn|Cho, Sung Won|Park, Neung Hwa|Namgoong, Suhg|Kim, Lyoung Hyo|Kim, Yoon Jun|Shin, Hyoung Doo | ||||||||||
| PMID: | 29238036 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Biol Macromol. 2018 Feb;107(Pt B):2171-2179. | ||||||||||
| Title: | Basil polysaccharide attenuates hepatocellular carcinoma metastasis in rat by suppressing H3K9me2 histone methylation under hepatic artery ligation-induced hypoxia. | ||||||||||
| Author: | Feng, Bing|Zhu, Ying|Su, Zuqing|Tang, Lipeng|Sun, Chaoyue|Li, Caiyun|Zheng, Guangjuan | ||||||||||
| PMID: | 29042275 | ||||||||||
| 14. | |||||||||||
| Journal: | Molecules. 2018 Mar 2;23(3). pii: molecules23030567. | ||||||||||
| Title: | Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search. | ||||||||||
| Author: | Ding, Hong|Lu, Wen Chao|Hu, Jun Chi|Liu, Yu-Chih|Zhang, Chen Hua|Lian, Fu Lin|Zhang, Nai Xia|Meng, Fan Wang|Luo, Cheng|Chen, Kai Xian | ||||||||||
| PMID: | 29498708 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncol Lett. 2018 Jun;15(6):9757-9765. | ||||||||||
| Title: | Increased expression of G9A contributes to carcinogenesis and indicates poor prognosis in hepatocellular carcinoma. | ||||||||||
| Author: | Qin, Jian|Li, Qingyun|Zeng, Zhi|Wu, Ping|Jiang, Yanping|Luo, Tao|Ji, Xiang|Zhang, Qiuping|Hao, Yarong|Chen, Lang | ||||||||||
| PMID: | 29928350 | ||||||||||
| 16. | |||||||||||
| Journal: | Hepatology. 2018 Jul 16. | ||||||||||
| Title: | Dual targeting of histone methyltransferase G9a and DNA-methyltransferase 1 for the treatment of experimental hepatocellular carcinoma. | ||||||||||
| Author: | Barcena-Varela, Marina|Caruso, Stefano|Llerena, Susana|Alvarez-Sola, Gloria|Uriarte, Iker|Latasa, M Ujue|Urtasun, Raquel|Rebouissou, Sandra|Alvarez, Laura|Jimenez, Maddalen|Santamaria, Eva|Rodriguez-Ortigosa, Carlos|Mazza, Giuseppe|Rombouts, Krista|Jose-E | ||||||||||
| PMID: | 30014490 | ||||||||||