Primary Site >> Colorectal Cancer

Gene >> EHMT2

Journal: Mol Cell Biol. 2008 May;28(10):3219-35.
Title: Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.
Author: Wu, Li-Peng|Wang, Xi|Li, Lian|Zhao, Ying|Lu, Shaoli|Yu, Yu|Zhou, Wen|Liu, Xiangyu|Yang, Jing|Zheng, Zhixin|Zhang, Hui|Feng, Jingnan|Yang, Yang|Wang, Haiying|Zhu, Wei-Guo
PMID: 18332107
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3086-96.
Title: Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer.
Author: de Vogel, Stefan|Wouters, Kim A D|Gottschalk, Ralph W H|van Schooten, Frederik J|de Goeij, Anton F P M|de Bruine, Adriaan P|Goldbohm, Royle A|van den Brandt, Piet A|Weijenberg, Matty P|van Engeland, Manon
PMID: 19843671
Journal: Autophagy. 2013 Dec;9(12):2126-39.
Title: BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.
Author: Kim, Yunha|Kim, Yong-Sook|Kim, Dong Eun|Lee, Jee Suk|Song, Ji Hoon|Kim, Ha-Gyeong|Cho, Dong-Hyung|Jeong, Seong-Yun|Jin, Dong-Hoon|Jang, Se Jin|Seol, Hyang-Sook|Suh, Young-Ah|Lee, Seung Jin|Kim, Choung-Soo|Koh, Jae-Young|Hwang, Jung Jin
PMID: 24322755
Journal: Oncotarget. 2015 Feb 20;6(5):2917-27.
Title: Down-regulation of G9a triggers DNA damage response and inhibits colorectal cancer cells proliferation.
Author: Zhang, Jie|He, Pengxing|Xi, Yong|Geng, Meiyu|Chen, Yi|Ding, Jian
PMID: 25595900
Journal: J Immunol. 2015 Aug 15;195(4):1868-82.
Title: H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.
Author: Paschall, Amy V|Yang, Dafeng|Lu, Chunwan|Choi, Jeong-Hyeon|Li, Xia|Liu, Feiyan|Figueroa, Mario|Oberlies, Nicholas H|Pearce, Cedric|Bollag, Wendy B|Nayak-Kapoor, Asha|Liu, Kebin
PMID: 26136424
Journal: Oncogene. 2016 Feb 11;35(6):793-9.
Title: H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.
Author: Olcina, M M|Leszczynska, K B|Senra, J M|Isa, N F|Harada, H|Hammond, E M
PMID: 25961932
Journal: Oncotarget. 2016 Jun 28;7(26):40594-40620.
Title: Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells.
Author: Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Kang, Hee Kyoung|Chang, Weon Young|Keum, Young Sam|Hyun, Jin Won
PMID: 27259240
Journal: Nat Cell Biol. 2016 Sep;18(9):993-1005.
Title: G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/beta-catenin pathway.
Author: Cha, Shih-Ting|Tan, Ching-Ting|Chang, Cheng-Chi|Chu, Chia-Yu|Lee, Wei-Jiunn|Lin, Been-Zen|Lin, Ming-Tsan|Kuo, Min-Liang
PMID: 27525719
Journal: Nat Cell Biol. 2016 Dec 23;19(1):76.
Title: Retraction: G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/beta-catenin pathway.
Author: Cha, Shih-Ting|Tan, Ching-Ting|Chang, Cheng-Chi|Chu, Chia-Yu|Lee, Wei-Jiunn|Lin, Been-Zen|Lin, Ming-Tsan|Kuo, Min-Liang
PMID: 28008183
Journal: Radiother Oncol. 2017 Sep;124(3):395-402.
Title: G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response.
Author: Luo, Chi-Wen|Wang, Jaw-Yuan|Hung, Wen-Chun|Peng, Guang|Tsai, Ya-Li|Chang, Tsung-Ming|Chai, Chee-Yin|Lin, Chih-Hung|Pan, Mei-Ren
PMID: 28351524
Journal: Theranostics. 2018 Apr 15;8(10):2884-2895.
Title: G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1.
Author: Zhang, Jie|Wang, Yafang|Shen, Yanyan|He, Pengxing|Ding, Jian|Chen, Yi
PMID: 29774081
Journal: Oncol Lett. 2018 Jun;15(6):8611-8619.
Title: Clinicopathological significance of G9A expression in colorectal carcinoma.
Author: Qin, Jian|Zeng, Zhi|Luo, Tao|Li, Qingyun|Hao, Yarong|Chen, Lang
PMID: 29805595
Journal: J Exp Clin Cancer Res. 2018 Oct 30;37(1):265.
Title: Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme.
Author: Li, Qi|Dong, Chengya|Cui, Jiayue|Wang, Yubo|Hong, Xinyu
PMID: 30376874