Primary Site >> Colorectal Cancer

Gene >> EGLN2

Journal: Cancer Res. 2003 Dec 15;63(24):8777-83.
Title: Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
Author: Erez, Neta|Milyavsky, Michael|Eilam, Raya|Shats, Igor|Goldfinger, Naomi|Rotter, Varda
PMID: 14695194
Journal: Gastroenterology. 2010 Feb;138(2):606-15.
Title: Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity.
Author: Xue, Jing|Li, Xuebing|Jiao, Shi|Wei, Ye|Wu, Guohao|Fang, Jing
PMID: 19786027
Journal: Biochem Biophys Res Commun. 2011 Jun 3;409(2):315-20.
Title: Prolyl hydroxylase domain protein 3 targets Pax2 for destruction.
Author: Yan, Bing|Jiao, Shi|Zhang, Hai-sheng|Lv, Dan-dan|Xue, Jing|Fan, Li|Wu, Guo-hao|Fang, Jing
PMID: 21575608
Journal: Exp Biol Med (Maywood). 2012 Jul;237(7):860-6.
Title: Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer.
Author: Xie, Ganfeng|Zheng, Lei|Ou, Juanjuan|Huang, Haihui|He, Jinxia|Li, Jianjun|Pan, Feng|Liang, Houjie
PMID: 22802519
Journal: BMC Cancer. 2013 Nov 6;13:526.
Title: Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.
Author: Rawluszko, Agnieszka A|Bujnicka, Katarzyna E|Horbacka, Karolina|Krokowicz, Piotr|Jagodzinski, Pawel P
PMID: 24195777
Journal: EMBO Mol Med. 2015 Oct;7(10):1350-65.
Title: PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Author: Deschoemaeker, Sofie|Di Conza, Giusy|Lilla, Sergio|Martin-Perez, Rosa|Mennerich, Daniela|Boon, Lise|Hendrikx, Stefanie|Maddocks, Oliver D K|Marx, Christian|Radhakrishnan, Praveen|Prenen, Hans|Schneider, Martin|Myllyharju, Johanna|Kietzmann, Thomas|Vousden
PMID: 26290450
Journal: Cancer Res. 2016 Apr 15;76(8):2219-30.
Title: Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells.
Author: Radhakrishnan, Praveenkumar|Ruh, Nadine|Harnoss, Jonathan M|Kiss, Judit|Mollenhauer, Martin|Scherr, Anna-Lena|Platzer, Lisa K|Schmidt, Thomas|Podar, Klaus|Opferman, Joseph T|Weitz, Juergen|Schulze-Bergkamen, Henning|Koehler, Bruno C|Ulrich, Alexis|Schneid
PMID: 26921340
Journal: Int J Biol Markers. 2017 Jul 24;32(3):e274-e277.
Title: An insertion/deletion polymorphism within the promoter of EGLN2 is associated with susceptibility to colorectal cancer.
Author: Li, Chaoyang|Feng, Lanjun|Niu, Luwei|Teng Li, Teng|Zhang, Bin|Wan, Huiping|Zhu, Zhansheng|Liu, Hao|Wang, Kai|Fu, Haixiao|Fu, Wei
PMID: 28218358
Journal: Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):540-546.
Title: Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.
Author: Xie, Yinghui|Yuan, Tanglong|Qin, Yanqing|Weng, Zhonghui|Fang, Jing
PMID: 29688249