Primary Site >> Colorectal Cancer
Gene >> EGLN2
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|
|
Ref: Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth. PMID: 14695194 |
Ref: Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity. PMID: 19786027 |
Ref: Prolyl hydroxylase domain protein 3 targets Pax2 for destruction. PMID: 21575608 |
Ref: Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer. PMID: 22802519 |
Ref: Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer. PMID: 24195777 |
Ref: PHD1 regulates p53-mediated colorectal cancer chemoresistance. PMID: 26290450 |
Ref: Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. PMID: 26921340 |
Ref: An insertion/deletion polymorphism within the promoter of EGLN2 is associated with susceptibility to colorectal cancer. PMID: 28218358 |
Ref: Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice. PMID: 29688249 |