Primary Site >> Colorectal Cancer
Gene >> EGLN1
| 1. | |||||||||||
| Journal: | Br J Cancer. 2009 Nov 17;101(10):1749-57. | ||||||||||
| Title: | Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. | ||||||||||
| Author: | Jubb, A M|Turley, H|Moeller, H C|Steers, G|Han, C|Li, J-L|Leek, R|Tan, E Y|Singh, B|Mortensen, N J|Noguera-Troise, I|Pezzella, F|Gatter, K C|Thurston, G|Fox, S B|Harris, A L | ||||||||||
| PMID: | 19844231 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterology. 2010 Feb;138(2):606-15. | ||||||||||
| Title: | Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity. | ||||||||||
| Author: | Xue, Jing|Li, Xuebing|Jiao, Shi|Wei, Ye|Wu, Guohao|Fang, Jing | ||||||||||
| PMID: | 19786027 | ||||||||||
| 3. | |||||||||||
| Journal: | Target Oncol. 2011 Sep;6(3):155-62. | ||||||||||
| Title: | LDH-A influences hypoxia-inducible factor 1alpha (HIF1 alpha) and is critical for growth of HT29 colon carcinoma cells in vivo. | ||||||||||
| Author: | Langhammer, Stefan|Najjar, Maher|Hess-Stumpp, Holger|Thierauch, Karl-Heinz | ||||||||||
| PMID: | 21660559 | ||||||||||
| 4. | |||||||||||
| Journal: | Exp Biol Med (Maywood). 2012 Jul;237(7):860-6. | ||||||||||
| Title: | Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer. | ||||||||||
| Author: | Xie, Ganfeng|Zheng, Lei|Ou, Juanjuan|Huang, Haihui|He, Jinxia|Li, Jianjun|Pan, Feng|Liang, Houjie | ||||||||||
| PMID: | 22802519 | ||||||||||
| 5. | |||||||||||
| Journal: | BMC Cancer. 2012 Jul 17;12:293. | ||||||||||
| Title: | Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition. | ||||||||||
| Author: | Chintala, Sreenivasulu|Najrana, Tanbir|Toth, Karoly|Cao, Shousong|Durrani, Farukh A|Pili, Roberto|Rustum, Youcef M | ||||||||||
| PMID: | 22804960 | ||||||||||
| 6. | |||||||||||
| Journal: | Biosci Rep. 2012 Dec;32(6):587-95. | ||||||||||
| Title: | Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. | ||||||||||
| Author: | Zhdanov, Alexander V|Dmitriev, Ruslan I|Papkovsky, Dmitri B | ||||||||||
| PMID: | 22943412 | ||||||||||
| 7. | |||||||||||
| Journal: | Chem Res Toxicol. 2012 Oct 15;25(10):2194-202. | ||||||||||
| Title: | Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1alpha stabilization in colon carcinoma cells. | ||||||||||
| Author: | Chowdhury, Rajdeep|Godoy, Luiz C|Thiantanawat, Apinya|Trudel, Laura J|Deen, William M|Wogan, Gerald N | ||||||||||
| PMID: | 22971010 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Radiat Biol. 2013 Jan;89(1):9-15. | ||||||||||
| Title: | Investigation of possible endogenous hypoxia markers in colorectal cancer. | ||||||||||
| Author: | Verstraete, Maud|Debucquoy, Annelies|Devos, Ellen|Sagaert, Xavier|Penninckx, Freddy|Begg, Adrian|Haustermans, Karin | ||||||||||
| PMID: | 22852555 | ||||||||||
| 9. | |||||||||||
| Journal: | BMC Cancer. 2013 Nov 6;13:526. | ||||||||||
| Title: | Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer. | ||||||||||
| Author: | Rawluszko, Agnieszka A|Bujnicka, Katarzyna E|Horbacka, Karolina|Krokowicz, Piotr|Jagodzinski, Pawel P | ||||||||||
| PMID: | 24195777 | ||||||||||
| 10. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2014 Jan 17;443(3):1008-13. | ||||||||||
| Title: | N-(2-Mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant. | ||||||||||
| Author: | Yum, Soohwan|Park, Huijeong|Hong, Sungchae|Jeong, Seongkeun|Kim, Wooseong|Jung, Yunjin | ||||||||||
| PMID: | 24361888 | ||||||||||
| 11. | |||||||||||
| Journal: | Fitoterapia. 2015 Jun;103:55-62. | ||||||||||
| Title: | HIF-prolyl hydroxylase is a potential molecular target for esculetin-mediated anti-colitic effects. | ||||||||||
| Author: | Yum, Soohwan|Jeong, Seongkeun|Lee, Sunyoung|Kim, Wooseong|Nam, Joon|Jung, Yunjin | ||||||||||
| PMID: | 25797536 | ||||||||||
| 12. | |||||||||||
| Journal: | EMBO Mol Med. 2015 Oct;7(10):1350-65. | ||||||||||
| Title: | PHD1 regulates p53-mediated colorectal cancer chemoresistance. | ||||||||||
| Author: | Deschoemaeker, Sofie|Di Conza, Giusy|Lilla, Sergio|Martin-Perez, Rosa|Mennerich, Daniela|Boon, Lise|Hendrikx, Stefanie|Maddocks, Oliver D K|Marx, Christian|Radhakrishnan, Praveen|Prenen, Hans|Schneider, Martin|Myllyharju, Johanna|Kietzmann, Thomas|Vousden | ||||||||||
| PMID: | 26290450 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Rep. 2017 Feb 14;18(7):1699-1712. | ||||||||||
| Title: | The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1alpha Levels and Colorectal Cancer Cell Survival under Hypoxia. | ||||||||||
| Author: | Di Conza, Giusy|Trusso Cafarello, Sarah|Loroch, Stefan|Mennerich, Daniela|Deschoemaeker, Sofie|Di Matteo, Mario|Ehling, Manuel|Gevaert, Kris|Prenen, Hans|Zahedi, Rene Peiman|Sickmann, Albert|Kietzmann, Thomas|Moretti, Fabiola|Mazzone, Massimiliano | ||||||||||
| PMID: | 28199842 | ||||||||||
| 14. | |||||||||||
| Journal: | Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1154-H1162. | ||||||||||
| Title: | Increased hypoxia-inducible factor-1alpha in striated muscle of tumor-bearing mice. | ||||||||||
| Author: | Devine, Raymond D|Bicer, Sabahattin|Reiser, Peter J|Wold, Loren E | ||||||||||
| PMID: | 28341633 | ||||||||||
| 15. | |||||||||||
| Journal: | Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):540-546. | ||||||||||
| Title: | Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice. | ||||||||||
| Author: | Xie, Yinghui|Yuan, Tanglong|Qin, Yanqing|Weng, Zhonghui|Fang, Jing | ||||||||||
| PMID: | 29688249 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Lett. 2018 Oct 17;440-441:145-155. | ||||||||||
| Title: | A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53. | ||||||||||
| Author: | Vidimar, Vania|Licona, Cynthia|Ceron-Camacho, Ricardo|Guerin, Eric|Coliat, Pierre|Venkatasamy, Aina|Ali, Moussa|Guenot, Dominique|Le Lagadec, Ronan|Jung, Alain C|Freund, Jean-Noel|Pfeffer, Michel|Mellitzer, Georg|Sava, Gianni|Gaiddon, Christian | ||||||||||
| PMID: | 30339780 | ||||||||||