Primary Site >> Liver Cancer

Gene >> EGFR

Journal: Shi Yan Sheng Wu Xue Bao. 1989 Dec;22(4):445-53.
Title: [EGFR expression and EGF stimulation of proliferation in human liver carcinoma cells].
Author: Xu, Y H|Jiang, W L|Peng, S F
PMID: 2560604
Journal: J Hepatol. 1992 Mar;14(2-3):377-80.
Title: c-erbB-2 oncogene expression in hepatocellular carcinoma and cholangiocarcinoma.
Author: Collier, J D|Guo, K|Mathew, J|May, F E|Bennett, M K|Corbett, I P|Bassendine, M F|Burt, A D
PMID: 1380026
Journal: Liver. 1993 Jun;13(3):151-5.
Title: Expression of transforming growth factor alpha in human hepatocellular carcinoma.
Author: Collier, J D|Guo, K|Gullick, W J|Bassendine, M F|Burt, A D
PMID: 8393123
Journal: J Gastroenterol. 1994 Oct;29(5):616-20.
Title: Serum levels of c-erbB-2 protein in digestive diseases.
Author: Motoo, Y|Sawabu, N|Yamaguchi, Y|Mouri, I|Yamakawa, O|Watanabe, H|Ohta, H|Okai, T|Makino, H
PMID: 7528080
Journal: Gan To Kagaku Ryoho. 1994 Jul;21(8):1245-53.
Title: [Clinical study of serum ErbB-2 protein using sandwich radioimmunometric assay (ErbB-2 IRMA 'Eiken')].
Author: Sugano, K|Kawai, T|Ishii, M|Koyama, H|Kitajima, M|Kasumi, F|Demura, R|Nakayama, T|Okabe, H|Mori, S
PMID: 7913312
Journal: Carcinogenesis. 1995 Jan;16(1):77-82.
Title: TGF alpha differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion.
Author: Miller, R T|Cattley, R C|Marsman, D S|Lyght, O|Popp, J A
PMID: 7530605
Journal: Hum Pathol. 1995 Oct;26(10):1126-32.
Title: Nodules of less-differentiated tumor within or adjacent to hepatocellular carcinoma: relative expression of transforming growth factor-alpha and its receptor in the different areas of tumor.
Author: Morimitsu, Y|Hsia, C C|Kojiro, M|Tabor, E
PMID: 7557946
Journal: Zhonghua Bing Li Xue Za Zhi. 1995 Apr;24(2):93-5.
Title: [Expression of c-erbB-2 protein and EGF receptor in hepatitis B, cirrhosis and hepatocellular carcinoma].
Author: Su, Q|Liu, Y
PMID: 7788735
Journal: Shi Yan Sheng Wu Xue Bao. 1995 Sep;28(3):241-6.
Title: [An EGFR antisense oligodeoxynucleotides and its phosphorothioate analogue inhibit the growth of human hepatocarcinoma BEL-7404 cells].
Author: Lin, J Q|Xu, Z S|Zhang, H Y|Yang, Z W|Xu, Y H
PMID: 8571707
Journal: Cancer Lett. 1996 Apr 19;102(1-2):65-71.
Title: Association of inhibition of cell growth by O-phospho-L-tyrosine with decreased tyrosine phosphorylation.
Author: Mishra, S|Hamburger, A W
PMID: 8603380
Journal: J Tongji Med Univ. 1996;16(1):6.
Title: The relationship between mast cell infiltration and the expression of PCNA and EGFr in experimental hepatocellular carcinoma of liver and squamous cell carcinoma of stomach in rats.
Author: Ruan, Y|Wu, Z|Ivankovic, S
PMID: 8758735
Journal: Hum Pathol. 1996 Aug;27(8):787-92.
Title: Detection of transforming growth factor-alpha protein and messenger RNA in hepatobiliary diseases by immunohistochemical and in situ hybridization techniques.
Author: Harada, K|Terada, T|Nakanuma, Y
PMID: 8760011
Journal: Cancer Lett. 1997 Jan 15;112(1):33-45.
Title: Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes.
Author: Masui, T|Nakanishi, H|Inada, K|Imai, T|Mizoguchi, Y|Yada, H|Futakuchi, M|Shirai, T|Tatematsu, M
PMID: 9029167
Journal: Cancer Res. 1997 Apr 15;57(8):1510-5.
Title: Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate.
Author: Reist, C J|Archer, G E|Wikstrand, C J|Bigner, D D|Zalutsky, M R
PMID: 9108453
Journal: Toxicol Pathol. 1997 May-Jun;25(3):275-83.
Title: Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver.
Author: Moser, G J|Wolf, D C|Goldsworthy, T L
PMID: 9210259
Journal: Liver. 1997 Aug;17(4):177-82.
Title: Expression of transforming growth factor alpha and epidermal growth factor receptor in human hepatocellular carcinoma.
Author: Kira, S|Nakanishi, T|Suemori, S|Kitamoto, M|Watanabe, Y|Kajiyama, G
PMID: 9298487
Journal: Clin Cancer Res. 1997 Jul;3(7):1059-66.
Title: Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas.
Author: Kiss, A|Wang, N J|Xie, J P|Thorgeirsson, S S
PMID: 9815784
Journal: Zhonghua Zhong Liu Za Zhi. 1997 May;19(3):170-2.
Title: [Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection].
Author: Wang, Q|Feng, X|Lin, Z
PMID: 10920888
Journal: Int J Oncol. 1999 Mar;14(3):453-60.
Title: Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: relationship to cell proliferation.
Author: Hisaka, T|Yano, H|Haramaki, M|Utsunomiya, I|Kojiro, M
PMID: 10024677
Journal: Liver. 1999 Aug;19(4):318-25.
Title: Transforming growth factor-alpha and epidermal growth factor receptor in chronic liver disease and hepatocellular carcinoma.
Author: Harada, K|Shiota, G|Kawasaki, H
PMID: 10459631
Journal: Int J Cancer. 2000 Feb 15;85(4):518-22.
Title: Malignant transformation and EGFR activation of immortalized mouse liver epithelial cells caused by HBV enhancer-X from a human hepatocellular carcinoma.
Author: Miyaki, M|Sato, C|Sakai, K|Konishi, M|Tanaka, K|Muraoka, M|Kikuchi-Yanoshita, R|Nadaoka, Y|Kanda, H|Kitagawa, T
PMID: 10699924
Journal: Toxicol Appl Pharmacol. 2000 Jun 1;165(2):115-26.
Title: EGF receptors of hepatocytes from rats treated with phenobarbital are sensitized to down-regulation by phenobarbital in culture.
Author: Dalton, S R|Jirtle, R L|Meyer, S A
PMID: 10828207
Journal: Br J Cancer. 2001 May 18;84(10):1377-83.
Title: Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma.
Author: Ito, Y|Takeda, T|Sakon, M|Tsujimoto, M|Higashiyama, S|Noda, K|Miyoshi, E|Monden, M|Matsuura, N
PMID: 11355950
Journal: Electrophoresis. 2001 Aug;22(14):3001-8.
Title: Proteome alterations in human hepatoma cells transfected with antisense epidermal growth factor receptor sequence.
Author: Yu, L R|Shao, X X|Jiang, W L|Xu, D|Chang, Y C|Xu, Y H|Xia, Q C
PMID: 11565794
Journal: J Cell Physiol. 2002 Dec;193(3):263-74.
Title: K vitamins, PTP antagonism, and cell growth arrest.
Author: Carr, Brian I|Wang, Ziqiu|Kar, Siddhartha
PMID: 12384979
Journal: J Clin Oncol. 2003 Feb 1;21(3):406-12.
Title: Thymidylate synthase expression in hepatic tumors is a predictor of survival and progression in patients with resectable metastatic colorectal cancer.
Author: Gonen, Mithat|Hummer, Amanda|Zervoudakis, Alice|Sullivan, Deidre|Fong, Yuman|Banerjee, Debabrata|Klimstra, David|Cordon-Cardo, Carlos|Bertino, Joseph|Kemeny, Nancy
PMID: 12560427
Journal: World J Gastroenterol. 2003 Mar;9(3):463-7.
Title: A novel HBV antisense RNA gene delivery system targeting hepatocellular carcinoma.
Author: Ma, Chun-Hong|Sun, Wen-Sheng|Tian, Pei-Kun|Gao, Li-Fen|Liu, Su-Xia|Wang, Xiao-Yan|Zhang, Li-Ning|Cao, Ying-Lin|Han, Li-Hui|Liang, Xiao-Hong
PMID: 12632498
Journal: Dig Liver Dis. 2003 May;35(5):332-8.
Title: Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours.
Author: Altimari, A|Fiorentino, M|Gabusi, E|Gruppioni, E|Corti, B|D'Errico, A|Grigioni, W F
PMID: 12846405
Journal: Toxicol Appl Pharmacol. 2003 Jul 15;190(2):135-45.
Title: Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice.
Author: Anna, Colleen H|Iida, Mari|Sills, Robert C|Devereux, Theodora R
PMID: 12878043
Journal: Beijing Da Xue Xue Bao Yi Xue Ban. 2003 Aug;35(4):340-7.
Title: [Identification and characterization of LAPTM4B encoded by a human hepatocellular carcinoma-associated novel gene].
Author: Liu, Xinrong|Zhou, Rouli|Zhang, Qingyun|Zhang, Ye|Shao, Genze|Jin, Yueying|Zhang, Sha|Lin, Ming|Rui, Jing'an|Ye, Daxiong
PMID: 12947545
Journal: Br J Cancer. 2004 Nov 29;91(11):1964-9.
Title: Laminin-5 offsets the efficacy of gefitinib ('Iressa') in hepatocellular carcinoma cells.
Author: Giannelli, G|Azzariti, A|Fransvea, E|Porcelli, L|Antonaci, S|Paradiso, A
PMID: 15545972
Journal: J Hepatol. 2005 Oct;43(4):661-9.
Title: Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics.
Author: Huether, Alexander|Hopfner, Michael|Sutter, Andreas P|Schuppan, Detlef|Scherubl, Hans
PMID: 16023762
Journal: Clin Exp Metastasis. 2005;22(2):137-47.
Title: Establishment and characterization of three novel human gastric cancer cell lines with differentiated intestinal phenotype derived from liver metastasis.
Author: Nakanishi, Hayao|Yasui, Kenzo|Ikehara, Yuzuru|Yokoyama, Hiroyuki|Munesue, Seiichi|Kodera, Yasuhiro|Tatematsu, Masae
PMID: 16086234
Journal: Biochem Pharmacol. 2006 Feb 14;71(4):479-85.
Title: ZD6474 inhibits proliferation and invasion of human hepatocellular carcinoma cells.
Author: Giannelli, Gianluigi|Azzariti, Amalia|Sgarra, Concetta|Porcelli, Letizia|Antonaci, Salvatore|Paradiso, Angelo
PMID: 16332356
Journal: Cancer Treat Rev. 2006 Feb;32(1):28-44.
Title: Cyclooxygenase-2 in hepatocellular carcinoma.
Author: Wu, Tong
PMID: 16337744
Journal: Oncogene. 2006 Jun 26;25(27):3787-800.
Title: Dysregulation of growth factor signaling in human hepatocellular carcinoma.
Author: Breuhahn, K|Longerich, T|Schirmacher, P
PMID: 16799620
Journal: APMIS. 2006 Jun;114(6):420-7.
Title: Immunohistochemical expression of CD95 (Fas), c-myc and epidermal growth factor receptor in hepatitis C virus infection, cirrhotic liver disease and hepatocellular carcinoma.
Author: El-Bassiouni, A|Nosseir, M|Zoheiry, M|El-Ahwany, E|Ghali, A|El-Bassiouni, N
PMID: 16856963
Journal: World J Gastroenterol. 2006 Aug 28;12(32):5160-7.
Title: Signaling pathways involved in the inhibition of epidermal growth factor receptor by erlotinib in hepatocellular cancer.
Author: Huether, Alexander|Hopfner, Michael|Sutter, Andreas P|Baradari, Viola|Schuppan, Detlef|Scherubl, Hans
PMID: 16937526
Journal: Hum Pathol. 2006 Oct;37(10):1324-32.
Title: Expression of betacellulin and epidermal growth factor receptor in hepatocellular carcinoma: implications for angiogenesis.
Author: Moon, Woo Sung|Park, Ho Sung|Yu, Ki Hoon|Park, Min Young|Kim, Kyung Ryoul|Jang, Kyu Yun|Kim, Jong Suk|Cho, Baik Hwan
PMID: 16949929
Journal: BMC Cancer. 2006 Dec 6;6:278.
Title: A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma.
Author: Bekaii-Saab, Tanios|Williams, Nita|Plass, Christoph|Calero, Miguel Villalona|Eng, Charis
PMID: 17150109
Journal: J Cancer Res Clin Oncol. 2007 Mar;133(3):145-52.
Title: Roles of EGFR-Stat3 signal pathway in carcinogenesis of experimental hepatoma in rats.
Author: Yu, Xiao Tang|Zhu, Shi Neng|Xu, Zu De|Hu, Xi Qi|Zhu, Teng Fang|Chen, Jie Qing|Lu, Shi Lun
PMID: 17031671
Journal: Ann Surg Oncol. 2007 Feb;14(2):752-8.
Title: COX-2 expression in hepatocellular carcinoma is an initiation event; while EGF receptor expression with downstream pathway activation is a prognostic predictor of survival.
Author: Foster, Jason|Black, Jennifer|LeVea, Charles|Khoury, Thaer|Kuvshinoff, Boris|Javle, Miland|Gibbs, John F
PMID: 17146741
Journal: J Gastroenterol Hepatol. 2007 Mar;22(3):436-43.
Title: Cimetidine inhibits epidermal growth factor-induced cell signaling.
Author: Fujikawa, Tatsuya|Shiraha, Hidenori|Nakanishi, Yutaka|Takaoka, Nobuyuki|Ueda, Naoki|Suzuki, Mayumi|Shiratori, Yasushi
PMID: 17295779
Journal: Liver Int. 2007 Mar;27(2):174-85.
Title: New molecular targets for hepatocellular carcinoma: the ErbB1 signaling system.
Author: Berasain, Carmen|Castillo, Josefa|Prieto, Jesus|Avila, Matias A
PMID: 17311611
Journal: Oncol Rep. 2007 Jul;18(1):279-85.
Title: Anti-tumor effects of immunotherapeutic peptide on the treatment of hepatocellular carcinoma with HBc carrier.
Author: Kong, Jing|Diao, Zhenyu|Deng, Xiaozhao|Zhong, Hui|Yao, Wenjuan|Hu, Xuefang
PMID: 17549380
Journal: Hepatol Res. 2007 Nov;37(11):957-65.
Title: Expression of Rab5a in hepatocellular carcinoma: Possible involvement in epidermal growth factor signaling.
Author: Fukui, Koji|Tamura, Shinji|Wada, Akira|Kamada, Yoshihiro|Igura, Takumi|Kiso, Shinichi|Hayashi, Norio
PMID: 17581187
Journal: Gastroenterol Hepatol. 2007 Jun-Jul;30(6):360-9.
Title: [Cell biology and genetics in liver cancer].
Author: Tovar, Victoria|Villanueva, Augusto|Llovet, Josep M
PMID: 17662221
Journal: Hepatogastroenterology. 2007 Jul-Aug;54(77):1339-44.
Title: Intestinal trefoil factor (TFF-3) and extracellular signal-regulated kinase (ERK) in cholangiocarcinoma.
Author: Ailawadhi, Sikander|Nagase, Hiroki|Khoury, Thaer|Yu, Jihnhee|Tan, Dongfeng|Black, Jennifer|Brattain, Michael|Javle, Milind
PMID: 17708250
Journal: Curr Pharm Des. 2007;13(32):3301-4.
Title: Tyrosine kinase inhibitors: a potential approach to the treatment of hepatocellular carcinoma.
Author: Giannelli, G|Napoli, N|Antonaci, S
PMID: 18045182
Journal: Transplantation. 2007 Nov 27;84(10):1262-71.
Title: Angiogenesis soluble factors as hepatocellular carcinoma noninvasive markers for monitoring hepatitis C virus cirrhotic patients awaiting liver transplantation.
Author: Mas, Valeria R|Maluf, Daniel G|Archer, Kellie J|Yanek, Kenneth C|Fisher, Robert A
PMID: 18049111
Journal: Gastrointest Cancer Res. 2007;1(4 Suppl 2):S13-21.
Title: Liver stem cells and molecular signaling pathways in hepatocellular carcinoma.
Author: Kitisin, Krit|Pishvaian, Michael J|Johnson, Lynt B|Mishra, Lopa
PMID: 19360142
Journal: J Cancer Res Clin Oncol. 2008 Apr;134(4):503-13.
Title: siRNA mediated the type 1 insulin-like growth factor receptor and epidermal growth factor receptor silencing induces chemosensitization of liver cancer cells.
Author: Niu, Jian|Li, Xiang-Nong|Qian, Haixin|Han, Zeguang
PMID: 17901981
Journal: J Hepatol. 2008 Jan;48(1):83-90.
Title: Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection.
Author: Schmitz, Klaus Juergen|Wohlschlaeger, Jeremias|Lang, Hauke|Sotiropoulos, Georgios Charalambos|Malago, Massimo|Steveling, Karen|Reis, Henning|Cicinnati, Vito Rosario|Schmid, Kurt Werner|Baba, Hideo Andreas
PMID: 17998146
Journal: Bull Cancer. 2008 Jan;95(1):117-20.
Title: [News in digestive oncology].
Author: Michel, Pierre|Di Fiore, Frederic
PMID: 18230577
Journal: Cancer Lett. 2008 Apr 18;262(2):257-64.
Title: EGFR and VEGFR as potential target for biological therapies in HCC cells.
Author: Giannelli, Gianluigi|Sgarra, Concetta|Porcelli, Letizia|Azzariti, Amalia|Antonaci, Salvatore|Paradiso, Angelo
PMID: 18248788
Journal: Cancer. 2008 Jun 15;112(12):2733-9.
Title: Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: results of a multicenter phase 2 study.
Author: Asnacios, Amani|Fartoux, Laetitia|Romano, Olivier|Tesmoingt, Chloe|Louafi S, Samy|Mansoubakht, Touraj|Artru, Pascal|Poynard, Thierry|Rosmorduc, Olivier|Hebbar, Mohamed|Taieb, Julien
PMID: 18412149
Journal: Hepatol Res. 2008 Aug;38(8):838-41.
Title: Lack of somatic ErbB2 tyrosine kinase domain mutations in hepatocellular carcinoma.
Author: Wong, Chiung-Ing|Yap, Hui-Ling|Lim, Seng-Gee|Guo, Jia-Yi|Goh, Boon-Cher|Lee, Soo-Chin
PMID: 18462377
Journal: Hepatol Int. 2008 Jun;2(2):213-21.
Title: Clinical impact of serum transforming growth factor-alpha mRNA as a predictive biomarker for the prognosis of fulminant hepatitis.
Author: Miura, Norimasa|Kabashima, Hiroko|Shimizu, Mika|Sato, Reina|Tsukamoto, Tomoe|Harada, Tomomi|Takahashi, Shunsaku|Endo, Ryujin|Nakayama, Nobuaki|Takikawa, Yasuhiro|Mochida, Satoshi|Suzuki, Kazuyuki|Hasegawa, Junichi|Shiota, Goshi
PMID: 19669307
Journal: Cancer Chemother Pharmacol. 2009 Sep;64(4):777-83.
Title: A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer.
Author: Ramanathan, Ramesh K|Belani, Chandra P|Singh, Deepti A|Tanaka, Michael|Lenz, Heinz-Josef|Yen, Yun|Kindler, Hedy L|Iqbal, Syma|Longmate, Jeff|Mack, Philip C|Lurje, Georg|Gandour-Edwards, Regina|Dancey, Janet|Gandara, David R
PMID: 19169683
Journal: Cancer Lett. 2009 Jun 28;279(1):30-8.
Title: Epidermal growth factor receptor vIII enhances tumorigenicity and resistance to 5-fluorouracil in human hepatocellular carcinoma.
Author: Wang, Huamao|Jiang, Hua|Zhou, Min|Xu, Zhibing|Liu, Shiguo|Shi, Bizhi|Yao, Xiao|Yao, Ming|Gu, JianRen|Li, Zonghai
PMID: 19217205
Journal: Nat Biotechnol. 2009 Mar;27(3):264-74.
Title: A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.
Author: Keng, Vincent W|Villanueva, Augusto|Chiang, Derek Y|Dupuy, Adam J|Ryan, Barbara J|Matise, Ilze|Silverstein, Kevin A T|Sarver, Aaron|Starr, Timothy K|Akagi, Keiko|Tessarollo, Lino|Collier, Lara S|Powers, Scott|Lowe, Scott W|Jenkins, Nancy A|Copeland, Neal
PMID: 19234449
Journal: J Hematol Oncol. 2009 Feb 23;2:9.
Title: Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.
Author: Javle, Milind|Hsueh, Chung-Tsen
PMID: 19236713
Journal: Ann N Y Acad Sci. 2009 Feb;1155:187-93.
Title: Aromatase in nontumoral and malignant human liver tissues and cells.
Author: Carruba, Giuseppe
PMID: 19250204
Journal: Rev Med Interne. 2009 May;30(5):416-24.
Title: [Targeted therapies and their indications in solid neoplasias].
Author: Dreyer, C|Raymond, E|Faivre, S
PMID: 19299048
Journal: Cancer Res. 2009 May 1;69(9):4059-66.
Title: Identification of potential driver genes in human liver carcinoma by genomewide screening.
Author: Woo, Hyun Goo|Park, Eun Sung|Lee, Ju-Seog|Lee, Yun-Han|Ishikawa, Tsuyoshi|Kim, Yoon Jun|Thorgeirsson, Snorri S
PMID: 19366792
Journal: Bull Cancer. 2009 May;96(5):553-61.
Title: [Targeted therapies in hepatocellular carcinomas: recent results and future development].
Author: Marijon, H|Faivre, S|Raymond, E
PMID: 19467986
Journal: Ecotoxicology. 2009 Aug;18(6):715-21.
Title: Transcriptional toxicity of the Yangtze River source water on mouse (Mus musculus) detected by cDNA microarray.
Author: Wu, Bing|Cheng, Shupei|Li, Yiqiang|Kong, Jie|Zhao, Dayong|Zhang, Yan|Zhang, Xuxiang
PMID: 19499331
Journal: Gan To Kagaku Ryoho. 2009 Jun;36(6):1003-6.
Title: [Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
Author: Yoda, Yusuke|Yoshino, Takayuki|Kadowaki, Shigenori|Bando, Hideaki|Okano, Susumu|Fukushima, Hiraku|Fuse, Nozomu|Tahara, Makoto|Doi, Toshihiko|Ohtsu, Atsushi
PMID: 19542725
Journal: Clin Cancer Res. 2009 Sep 15;15(18):5895-901.
Title: A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas.
Author: Bekaii-Saab, Tanios|Markowitz, Joseph|Prescott, Nichole|Sadee, Wolfgang|Heerema, Nyla|Wei, Lai|Dai, Zunyan|Papp, Audrey|Campbell, Angela|Culler, Kristy|Balint, Catherine|O'Neil, Bert|Lee, Ruey-Min|Zalupski, Mark|Dancey, Janet|Chen, Helen|Grever, Michael|E
PMID: 19737952
Journal: Pathobiology. 2009;76(5):267-73.
Title: Antisense phosphorothioate oligodeoxynucleic acid for CD10 suppresses liver metastasis of colorectal cancer.
Author: Luo, Yi|Fujii, Kiyomu|Ohmori, Hitoshi|Sasahira, Tomonori|Moriwaka, Yukiko|Isobe, Mamoru|Kuniyasu, Hiroki
PMID: 19816087
Journal: J Mater Sci Mater Med. 2010 Feb;21(2):551-6.
Title: Preparation of EGFR monoclonal antibody conjugated nanoparticles and targeting to hepatocellular carcinoma.
Author: Liu, Peifeng|Li, Zonghai|Zhu, Mingjie|Sun, Ying|Li, Yaogang|Wang, Hongzhi|Duan, Yourong
PMID: 19921404
Journal: Oncol Rep. 2010 Jan;23(1):151-7.
Title: The mitogenic effectors of isoproterenol in human hepatocellular carcinoma cells.
Author: Yuan, Aihua|Li, Zongfang|Li, Xinqiu|Yi, Shanyong|Wang, Shukui|Cai, Yongdong|Cao, Hongyong
PMID: 19956875
Journal: J Endocrinol. 2010 Mar;204(3):299-309.
Title: GH modulates hepatic epidermal growth factor signaling in the mouse.
Author: Gonzalez, Lorena|Diaz, Ma Eugenia|Miquet, Johanna G|Sotelo, Ana I|Fernandez, Diego|Dominici, Fernando P|Bartke, Andrzej|Turyn, Daniel
PMID: 20032199
Journal: Bioorg Med Chem. 2010 Feb;18(3):1117-23.
Title: Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents.
Author: Lv, Peng-Cheng|Wang, Kai-Rui|Li, Qing-Shan|Chen, Jin|Sun, Juan|Zhu, Hai-Liang
PMID: 20056425
Journal: Arch Toxicol. 2010 Feb;84(2):155-64.
Title: Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.
Author: Kawai, Masaomi|Saegusa, Yukie|Dewa, Yasuaki|Nishimura, Jihei|Kemmochi, Sayaka|Harada, Tomoaki|Ishii, Yuji|Umemura, Takashi|Shibutani, Makoto|Mitsumori, Kunitoshi
PMID: 20101389
Journal: Am J Transl Res. 2010 Jan 23;2(1):105-18.
Title: Molecular genetics of hepatocellular neoplasia.
Author: Jain, Shilpa|Singhal, Shashideep|Lee, Peng|Xu, Ruliang
PMID: 20182587
Journal: Eur J Med Chem. 2010 Jul;45(7):3184-90.
Title: Synthesis and antiproliferative activity of indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line.
Author: Shen, Yong-Miao|Lv, Peng-Cheng|Chen, Wu|Liu, Peng-Gang|Zhang, Ming-Zhu|Zhu, Hai-Liang
PMID: 20304535
Journal: Expert Opin Investig Drugs. 2010 May;19(5):663-72.
Title: Beyond sorafenib: novel targeted therapies for advanced hepatocellular carcinoma.
Author: Zhu, Andrew X
PMID: 20367287
Journal: Onkologie. 2010;33(5):263-9.
Title: Hepatoid adenocarcinoma - review of the literature illustrated by a rare case originating in the peritoneal cavity.
Author: Metzgeroth, Georgia|Strobel, Philipp|Baumbusch, Tobias|Reiter, Andreas|Hastka, Jan
PMID: 20502062
Journal: Oncol Rep. 2010 Aug;24(2):441-8.
Title: Gastrin-releasing peptide promotes the growth of HepG2 cells via EGFR-independent ERK1/2 activation.
Author: Li, Xinqiu|Lv, Yunfu|Yuan, Aihua|Yi, Shanyong|Ma, Yong|Li, Zongfang
PMID: 20596631
Journal: Hepatology. 2010 Sep;52(3):975-86.
Title: Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy.
Author: Zhang, Zichen|Oyesanya, Regina A|Campbell, Deanna J W|Almenara, Jorge A|Dewitt, Jennifer L|Sirica, Alphonse E
PMID: 20607690
Journal: BMC Gastroenterol. 2010 Jul 9;10:79.
Title: Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor.
Author: Fujii, Tsutomu|Fuchs, Bryan C|Yamada, Suguru|Lauwers, Gregory Y|Kulu, Yakup|Goodwin, Jonathan M|Lanuti, Michael|Tanabe, Kenneth K
PMID: 20618941
Journal: Cancer Lett. 2011 Feb 1;301(1):47-56.
Title: Inhibition of poly (ADP-ribose) polymerase-1 enhances doxorubicin activity against liver cancer cells.
Author: Munoz-Gamez, J A|Quiles-Perez, R|Ruiz-Extremera, A|Martin-Alvarez, A B|Sanjuan-Nunez, Laura|Carazo, A|Leon, Josefa|Oliver, F J|Salmeron, J
PMID: 21093979
Journal: Front Biosci (Schol Ed). 2011 Jan 1;3:16-22.
Title: Targeting EGFR in bilio-pancreatic and liver carcinoma.
Author: Fratto, Maria Elisabetta|Santini, Daniele|Vincenzi, Bruno|Silvestris, Nicola|Azzariti, Amalia|Tommasi, Stefania|Zoccoli, Alice|Galluzzo, Sara|Maiello, Evaristo|Colucci, Giuseppe|Tonini, Giuseppe
PMID: 21196353
Journal: Eur J Pharm Sci. 2011 Mar 18;42(4):387-91.
Title: Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT.
Author: Hu, Yurong|Shen, Yingying|Ji, Baofang|Wang, Lei|Zhang, Zhenzhong|Zhang, Yun
PMID: 21238587
Journal: Biochem Pharmacol. 2011 Apr 1;81(7):917-24.
Title: The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-beta-induced apoptosis of liver tumor cells.
Author: Sancho, Patricia|Fabregat, Isabel
PMID: 21276422
Journal: Alcohol Clin Exp Res. 2011 May;35(5):821-5.
Title: Molecular pathogenesis of hepatocellular carcinoma.
Author: Cornella, Helena|Alsinet, Clara|Villanueva, Augusto
PMID: 21303380
Journal: J Cell Physiol. 2011 Jul;226(7):1934-9.
Title: Oncosuppressor methylation: a possible key role in colon metastatic progression.
Author: Tommasi, Stefania|Pinto, Rosamaria|Petriella, Daniela|Pilato, Brunella|Lacalamita, Rosanna|Santini, Daniele|Zito, Francesco|Colucci, Giuseppe|Paradiso, Angelo|Silvestris, Nicola
PMID: 21506124
Journal: Cancer Res. 2011 Jun 1;71(11):4028-39.
Title: EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis.
Author: Cheng, Alfred S L|Lau, Suki S|Chen, Yangchao|Kondo, Yutaka|Li, May S|Feng, Hai|Ching, Arthur K|Cheung, Kin F|Wong, Hoi K|Tong, Joanna H|Jin, Hongchuan|Choy, Kwong W|Yu, Jun|To, Ka F|Wong, Nathalie|Huang, Tim H-M|Sung, Joseph J Y
PMID: 21512140
Journal: Semin Liver Dis. 2011 May;31(2):173-87.
Title: Genetics of hepatobiliary carcinogenesis.
Author: Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 21538283
Journal: Hepatology. 2011 Sep 2;54(3):1031-42.
Title: Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.
Author: Marquardt, Jens U|Raggi, Chiara|Andersen, Jesper B|Seo, Daekwan|Avital, Itzhak|Geller, David|Lee, Yun-Han|Kitade, Mitsuteru|Holczbauer, Agnes|Gillen, Matthew C|Conner, Elizabeth A|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 21618577
Journal: Biochem J. 2011 Sep 1;438(2):349-58.
Title: Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
Author: Liu, Zi-Miao|Tseng, Joseph T|Hong, Duang-Yang|Huang, Huei-Sheng
PMID: 21649584
Journal: Pathobiology. 2011;78(2):76-89.
Title: Changing pathology with changing drugs: tumors of the gastrointestinal tract.
Author: Cervera, Pascale|Flejou, Jean-Francois
PMID: 21677471
Journal: Liver Transpl. 2011 Nov;17(11):1292-8.
Title: Renal function in patients undergoing transplantation for nonalcoholic steatohepatitis cirrhosis: time to reconsider immunosuppression regimens?
Author: Houlihan, Diarmaid D|Armstrong, Matthew J|Davidov, Yana|Hodson, James|Nightingale, Peter|Rowe, Ian A|Paris, Sue|Gunson, Bridget K|Bramhall, Simon B|Mutimer, David J|Neuberger, James M|Newsome, Philip N
PMID: 21761549
Journal: Dig Dis. 2011;29(3):273-7.
Title: Molecular targeted therapy for hepatocellular carcinoma: bench to bedside.
Author: Kudo, Masatoshi
PMID: 21829017
Journal: Biochem Pharmacol. 2011 Dec 1;82(11):1583-92.
Title: The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.
Author: Caja, Laia|Sancho, Patricia|Bertran, Esther|Ortiz, Conrad|Campbell, Jean S|Fausto, Nelson|Fabregat, Isabel
PMID: 21864510
Journal: Cancer Cell Int. 2011 Nov 17;11:40.
Title: Involvement of the epidermal growth factor receptor in the modulation of multidrug resistance in human hepatocellular carcinoma cells in vitro.
Author: Hoffmann, Katrin|Xiao, Zhi|Franz, Clemens|Mohr, Elvira|Serba, Susanne|Buchler, Markus W|Schemmer, Peter
PMID: 22088142
Journal: Anticancer Res. 2011 Nov;31(11):3883-90.
Title: Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Author: Hoffmann, Katrin|Shibo, Lin|Xiao, Zhi|Longerich, Thomas|Buchler, Markus W|Schemmer, Peter
PMID: 22110214
Journal: Gan To Kagaku Ryoho. 2011 Nov;38(12):2244-6.
Title: [Three cases of patients in their eighties who received anti-EGFR antibody mono-therapy as first-line treatment for metastatic colorectal cancer].
Author: Katsumoto, Yoshihiro|Aritake, Noriko|Endoh, Akira|Ueda, Naoki|Inami, Naokuni
PMID: 22202343
Journal: Biomaterials. 2012 Jan;33(1):270-82.
Title: EGFR-specific PEGylated immunoliposomes for active siRNA delivery in hepatocellular carcinoma.
Author: Gao, Jie|Yu, Yongsheng|Zhang, Yingying|Song, Jinjing|Chen, Huaiwen|Li, Wei|Qian, Weizhu|Deng, Li|Kou, Geng|Chen, Jianming|Guo, Yajun
PMID: 21963149
Journal: Arch Toxicol. 2012 Mar;86(3):497-507.
Title: Mechanistic study on liver tumor promoting effects of flutamide in rats.
Author: Tawfeeq, Mohammad Monir|Hayashi, Hitomi|Shimamoto, Keisuke|Suzuki, Kazuhiko|Shibutani, Makoto|Inokuma, Hisashi|Mitsumori, Kunitoshi
PMID: 22076107
Journal: Carcinogenesis. 2012 Jan;33(1):203-8.
Title: Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer.
Author: Mabrok, Hoda B|Klopfleisch, Robert|Ghanem, Kadry Z|Clavel, Thomas|Blaut, Michael|Loh, Gunnar
PMID: 22080573
Journal: Oncologist. 2012;17(1):13.
Title: Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Author: Chiorean, E Gabriela|Ramasubbaiah, Rashmi|Yu, Menggang|Picus, Joel|Bufill, Jose A|Tong, Yan|Coleman, Nicki|Johnston, Erica L|Currie, Colleen|Loehrer, Patrick J
PMID: 22210086
Journal: Biochem J. 2012 May 1;443(3):691-700.
Title: Cross-talk between TGFbeta1 and EGFR signalling pathways induces TM4SF5 expression and epithelial-mesenchymal transition.
Author: Kang, Minkyung|Choi, Suyong|Jeong, Soo-Jin|Lee, Sin-Ae|Kwak, Tae Kyoung|Kim, Hyeonjung|Jung, Oisun|Lee, Mi-Sook|Ko, Youra|Ryu, Jihye|Choi, Yoon-Ju|Jeong, Doyoung|Lee, Hyo Jeong|Ye, Sang-Kyu|Kim, Sung-Hoon|Lee, Jung Weon
PMID: 22292774
Journal: BMC Cancer. 2012 Mar 13;12:88.
Title: Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases.
Author: Kuramochi, Hidekazu|Nakajima, Go|Kaneko, Yuka|Nakamura, Ayako|Inoue, Yuji|Yamamoto, Masakazu|Hayashi, Kazuhiko
PMID: 22409860
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Feb;33(2):215-9.
Title: [Association of genetic polymorphisms of key molecules in JAK/STAT signaling pathway with susceptibility of hepatocellular carcinoma].
Author: Xie, Jia-xin|Yin, Jian-hua|Zhang, Qi|Pu, Rui|Zhang, Yu-wei|Lu, Wen-ying|Cao, Guang-wen
PMID: 22575147
Journal: EMBO Mol Med. 2012 Aug;4(8):743-60.
Title: DIAPH3 governs the cellular transition to the amoeboid tumour phenotype.
Author: Hager, Martin H|Morley, Samantha|Bielenberg, Diane R|Gao, Sizhen|Morello, Matteo|Holcomb, Ilona N|Liu, Wennuan|Mouneimne, Ghassan|Demichelis, Francesca|Kim, Jayoung|Solomon, Keith R|Adam, Rosalyn M|Isaacs, William B|Higgs, Henry N|Vessella, Robert L|Di Vi
PMID: 22593025
Journal: Curr Med Chem. 2012;19(22):3722-9.
Title: Hepatocellular carcinoma: important biomarkers and their significance in molecular diagnostics and therapy.
Author: Sengupta, B|Siddiqi, S A
PMID: 22680921
Journal: Expert Opin Investig Drugs. 2012 Sep;21(9):1417-26.
Title: Sorafenib in non-small cell lung cancer.
Author: Zhang, Jianjun|Gold, Kathryn A|Kim, Edward
PMID: 22725255
Journal: Glycoconj J. 2012 Aug;29(5-6):411-24.
Title: Surface glycoproteomic analysis of hepatocellular carcinoma cells by affinity enrichment and mass spectrometric identification.
Author: Mi, Wei|Jia, Wei|Zheng, Zhaobin|Wang, Jinglan|Cai, Yun|Ying, Wantao|Qian, Xiaohong
PMID: 22752401
Journal: PLoS One. 2012;7(6):e39981.
Title: Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling.
Author: Koga, Hironori|Tsedensodnom, Orkhontuya|Tomimaru, Yoshito|Walker, Evan J|Lee, Han Chu|Kim, Kang Mo|Yano, Hirohisa|Wands, Jack R|Kim, Miran
PMID: 22768190
Journal: PLoS One. 2012;7(7):e40638.
Title: The transcription factor c-Jun protects against liver damage following activated beta-Catenin signaling.
Author: Trierweiler, Claudia|Blum, Hubert E|Hasselblatt, Peter
PMID: 22792392
Journal: Asian Pac J Cancer Prev. 2012;13(4):1457-61.
Title: HGFK1 is associated with a better prognosis and reverses inhibition by gefitinib in NSCLC cases.
Author: Zhou, Xiao-Hui|Tang, Li-Na|Yue, Lu|Min, Da-Liu|Yang, Yi|Huang, Jian-An|Shen, Zan
PMID: 22799348
Journal: Asian Pac J Cancer Prev. 2012;13(5):2009-14.
Title: Tas13D inhibits growth of SMMC-7721 cell via suppression VEGF and EGF expression.
Author: He, Huai-Zhen|Wang, Nan|Zhang, Jie|Zheng, Lei|Zhang, Yan-Min
PMID: 22901163
Journal: Bioorg Med Chem. 2012 Oct 15;20(20):6144-53.
Title: Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity.
Author: Chen, Kuen-Feng|Pao, Kuan-Chuan|Su, Jung-Chen|Chou, Yi-Chieh|Liu, Chun-Yu|Chen, Hui-Ju|Huang, Jui-Wen|Kim, InKi|Shiau, Chung-Wai
PMID: 22980218
Journal: Biol Chem. 2012 Oct;393(10):1183-91.
Title: Dual-specificity phosphatases are targets of the Wnt/beta-catenin pathway and candidate mediators of beta-catenin/Ras signaling interactions.
Author: Zeller, Eva|Mock, Katharina|Horn, Moritz|Colnot, Sabine|Schwarz, Michael|Braeuning, Albert
PMID: 23089536
Journal: Asian Pac J Cancer Prev. 2012;13(8):3967-71.
Title: Multivariate analysis of molecular indicators for postoperative liver metastasis in colorectal cancer cases.
Author: Qian, Li-Yuan|Li, Ping|Li, Xiao-Rong|Chen, Dao-Jin|Zhu, Shai-Hong
PMID: 23098501
Journal: Pathol Oncol Res. 2013 Jan;19(1):63-70.
Title: Molecular characteristics of fibrolamellar hepatocellular carcinoma.
Author: Patonai, Attila|Erdelyi-Belle, Boglarka|Korompay, Anna|Somoracz, Aron|Torzsok, Peter|Kovalszky, Ilona|Barbai, Tamas|Raso, Erzsebet|Lotz, Gabor|Schaff, Zsuzsa|Kiss, Andras
PMID: 22872444
Journal: Hepatology. 2013 Jan;57(1):120-30.
Title: Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.
Author: Keng, Vincent W|Sia, Daniela|Sarver, Aaron L|Tschida, Barbara R|Fan, Danhua|Alsinet, Clara|Sole, Manel|Lee, Wai L|Kuka, Timothy P|Moriarity, Branden S|Villanueva, Augusto|Dupuy, Adam J|Riordan, Jesse D|Bell, Jason B|Silverstein, Kevin A T|Llovet, Josep M|
PMID: 22899566
Journal: Biochim Biophys Acta. 2013 Mar;1833(3):629-42.
Title: The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation.
Author: Jung, Oisun|Choi, Yoon-Ju|Kwak, Tae Kyoung|Kang, Minkyung|Lee, Mi-Sook|Ryu, Jihye|Kim, Hye-Jin|Lee, Jung Weon
PMID: 23220047
Journal: Yonsei Med J. 2013 Jan 1;54(1):1-14.
Title: The role of pharmacoethnicity in the development of cytotoxic and molecular targeted drugs in oncology.
Author: Saijo, Nagahiro
PMID: 23225792
Journal: World J Gastroenterol. 2013 Feb 7;19(5):654-64.
Title: Clinical impact of hepatitis B and C virus envelope glycoproteins.
Author: Jeulin, Helene|Velay, Aurelie|Murray, John|Schvoerer, Evelyne
PMID: 23429668
Journal: Int J Oncol. 2013 May;42(5):1833-41.
Title: Prostaglandin E(2) receptor EP1-mediated phosphorylation of focal adhesion kinase enhances cell adhesion and migration in hepatocellular carcinoma cells.
Author: Bai, Xiaoming|Wang, Jie|Zhang, Li|Ma, Juan|Zhang, Hai|Xia, Shukai|Zhang, Min|Ma, Xiuping|Guo, Yan|Rong, Rong|Cheng, Shanyu|Shu, Wei|Wang, Yipin|Leng, Jing
PMID: 23525457
Journal: Am J Pathol. 2013 May;182(5):1648-58.
Title: Role and regulation of PDGFRalpha signaling in liver development and regeneration.
Author: Awuah, Prince K|Nejak-Bowen, Kari N|Monga, Satdarshan P S
PMID: 23529017
Journal: Oncol Rep. 2013 Jun;29(6):2211-8.
Title: Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.
Author: Xu, Kedong|Gao, Jie|Yang, Xue|Yao, Yingmin|Liu, Qingguang
PMID: 23545718
Journal: Environ Sci Pollut Res Int. 2013 Sep;20(9):6468-81.
Title: Signal transduction disturbance related to hepatocarcinogenesis in mouse by prolonged exposure to Nanjing drinking water.
Author: Zhang, Rui|Sun, Jie|Zhang, Yan|Cheng, Shupei|Zhang, Xiaowei
PMID: 23591932
Journal: BMC Cancer. 2013 May 30;13:267.
Title: Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.
Author: Chang, Alex Y|Wang, Miao
PMID: 23721490
Journal: PLoS One. 2013 Jun 13;8(6):e64260.
Title: Actionable gene expression-based patient stratification for molecular targeted therapy in hepatocellular carcinoma.
Author: Kwon, Jung-Hee|Lee, Namgyu|Park, Jin Young|Yu, Yun Suk|Kim, Jin Pyo|Shin, Ji Hye|Kim, Dong-Sik|Joh, Jae Won|Kim, Dae Shick|Choi, Kwan Yong|Kang, Koo-Jeong|Kim, Gundo|Moon, Young Ho|Wang, Hee Jung
PMID: 23785399
Journal: Genet Test Mol Biomarkers. 2013 Aug;17(8):595-600.
Title: Association of epidermal growth factor and epidermal growth factor receptor polymorphisms with the risk of hepatitis B virus-related hepatocellular carcinoma in the population of North China.
Author: Wu, Jia|Zhang, Wei|Xu, Aiqiang|Zhang, Li|Yan, Tao|Li, Zhuo|Wu, Xiaopan|Zhu, Xilin|Ma, Juan|Li, Ke|Li, Hui|Liu, Ying
PMID: 23790025
Journal: Cancer Biol Ther. 2013 Aug;14(8):703-10.
Title: Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer.
Author: Al-Marrawi, Mhd Yaser|Saroya, Bikramajit Singh|Brennan, Matthew C|Yang, Zhaohai|Dykes, Thomas M|El-Deiry, Wafik S
PMID: 23792568
Journal: J BUON. 2013 Apr-Jun;18(2):477-85.
Title: Triterpenoid pristimerin induced HepG2 cells apoptosis through ROS-mediated mitochondrial dysfunction.
Author: Guo, Yan|Zhang, Wei|Yan, Yan-Yan|Ma, Cun-Gen|Wang, Xia|Wang, Chen|Zhao, Jia-Li
PMID: 23818365
Journal: Med Oncol. 2013;30(3):673.
Title: Epidermal growth factor, its receptor and transforming growth factor-beta1 in the diagnosis of HCV-induced hepatocellular carcinoma.
Author: Shehata, Fatma|Abdel Monem, Nihad|Sakr, Mohamed|Kasem, Samar|Balbaa, Mahmoud
PMID: 23912699
Journal: Gastroenterology. 2013 Dec;145(6):1436-48.e1-12.
Title: MUC15 inhibits dimerization of EGFR and PI3K-AKT signaling and is associated with aggressive hepatocellular carcinomas in patients.
Author: Wang, Ruo-Yu|Chen, Lei|Chen, Hai-Yang|Hu, Liang|Li, Liang|Sun, Han-Yong|Jiang, Feng|Zhao, Jing|Liu, Gao-Mi-Yang|Tang, Jing|Chen, Cai-Yang|Yang, Ying-Cheng|Chang, Yan-Xin|Liu, Hui|Zhang, Jin|Yang, Yuan|Huang, Gang|Shen, Feng|Wu, Meng-Chao|Zhou, Wei-Ping|Wa
PMID: 23933603
Journal: Biomaterials. 2013 Dec;34(38):10084-98.
Title: Inhibition of hepatocellular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA.
Author: Gao, Jie|Chen, Huaiwen|Yu, Yongsheng|Song, Jinjing|Song, Hao|Su, Xiao|Li, Wei|Tong, Xin|Qian, Weizhu|Wang, Hao|Dai, Jianxin|Guo, Yajun
PMID: 24060417
Journal: BMC Cancer. 2013 Oct 2;13:448.
Title: MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells.
Author: Wang, Lumin|Yao, Jiayi|Shi, Xin|Hu, Lili|Li, Zongfang|Song, Tusheng|Huang, Chen
PMID: 24083596
Journal: Biochem Pharmacol. 2013 Dec 15;86(12):1721-30.
Title: Novel compound PS-101 exhibits selective inhibition in non-small-cell lung cancer cell by blocking the EGFR-driven antiapoptotic pathway.
Author: Zhang, Guo-Hai|Cai, Le-Jing|Wang, Yan-Fei|Zhou, Yuan-Hua|An, Yun-Feng|Liu, Yan-Cheng|Peng, Yan|Chen, Zhen-Feng|Liang, Hong
PMID: 24161785
Journal: PLoS One. 2013 Nov 4;8(11):e78624.
Title: iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Author: Ozdemir, Bahadir|Abd-Almageed, Wael|Roessler, Stephanie|Wang, Xin Wei
PMID: 24223834
Journal: Liver Cancer. 2013 Aug;2(3-4):345-64.
Title: Clinical trials in hepatocellular carcinoma: an update.
Author: Shen, Ying-Chun|Lin, Zhong-Zhe|Hsu, Chih-Hung|Hsu, Chiun|Shao, Yu-Yun|Cheng, Ann-Lii
PMID: 24400222
Journal: J Carcinog. 2013 Dec 31;12:22.
Title: Targeted therapies in development for non-small cell lung cancer.
Author: Reungwetwattana, Thanyanan|Dy, Grace Kho
PMID: 24574860
Journal: Nanomedicine (Lond). 2014 Feb;9(2):279-93.
Title: Polymer-lipid hybrid nanoparticles conjugated with anti-EGF receptor antibody for targeted drug delivery to hepatocellular carcinoma.
Author: Gao, Jie|Xia, Yu|Chen, Huaiwen|Yu, Yongsheng|Song, Jinjing|Li, Wei|Qian, Weizhu|Wang, Hao|Dai, Jianxin|Guo, Yajun
PMID: 23721168
Journal: Cancer Lett. 2014 Jan 1;342(1):113-20.
Title: The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III.
Author: Jiang, Hua|Dong, Qiongna|Luo, Xiaoying|Shi, Bizhi|Wang, Huamao|Gao, Huiping|Kong, Juan|Zhang, Jiqin|Li, Zonghai
PMID: 24007863
Journal: J Cell Mol Med. 2014 Feb;18(2):218-30.
Title: The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment.
Author: Huang, Peixin|Xu, Xiaojing|Wang, Lingyan|Zhu, Bijun|Wang, Xiangdong|Xia, Jingling
PMID: 24268047
Journal: J Gastroenterol. 2014 Jan;49(1):9-23.
Title: The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis.
Author: Berasain, Carmen|Avila, Matias A
PMID: 24318021
Journal: Technol Cancer Res Treat. 2014 Aug;13(4):377-85.
Title: Combination of cetuximab and rapamycin enhances the therapeutic efficacy in hepatocellular carcinoma.
Author: Geng, J|Li, X|Lang, X|Qiao, C|Hu, M|Yang, J|Feng, J|Lv, M
PMID: 24325131
Journal: Matrix Biol. 2014 Apr;35:194-205.
Title: Decorin deficiency promotes hepatic carcinogenesis.
Author: Horvath, Zsolt|Kovalszky, Ilona|Fullar, Alexandra|Kiss, Katalin|Schaff, Zsuzsa|Iozzo, Renato V|Baghy, Kornelia
PMID: 24361483
Journal: Int J Oncol. 2014 Mar;44(3):769-80.
Title: Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression.
Author: Zhang, Hai|Cheng, Shanyu|Zhang, Min|Ma, Xiuping|Zhang, Li|Wang, Yipin|Rong, Rong|Ma, Juan|Xia, Shukai|Du, Mingzhan|Shi, Feng|Wang, Jie|Yang, Qinyi|Bai, Xiaoming|Leng, Jing
PMID: 24378923
Journal: J Hepatol. 2014 Jun;60(6):1225-34.
Title: Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling.
Author: Li, Jun|Yang, Xiao-Mei|Wang, Ya-Hui|Feng, Ming-Xuan|Liu, Xiao-Jin|Zhang, Yan-Li|Huang, Shuo|Wu, Zheng|Xue, Feng|Qin, Wen-Xin|Gu, Jian-Ren|Xia, Qiang|Zhang, Zhi-Gang
PMID: 24607627
Journal: Oncol Rep. 2014 May;31(5):2099-106.
Title: Prostaglandin E(2) receptor EP2 mediates Snail expression in hepatocellular carcinoma cells.
Author: Cheng, Shan-Yu|Zhang, Hai|Zhang, Min|Xia, Shu-Kai|Bai, Xiao-Ming|Zhang, Li|Ma, Juan|Rong, Rong|Wang, Yi-Pin|Du, Ming-Zhan|Wang, Jie|Chen, Meng|Shi, Feng|Yang, Qin-Yi|Leng, Jing
PMID: 24626807
Journal: Nanomedicine. 2014 Aug;10(6):1121-30.
Title: Gold nanoparticles and radiofrequency in experimental models for hepatocellular carcinoma.
Author: Raoof, Mustafa|Corr, Stuart J|Zhu, Cihui|Cisneros, Brandon T|Kaluarachchi, Warna D|Phounsavath, Sophia|Wilson, Lon J|Curley, Steven A
PMID: 24650884
Journal: Hepatology. 2014 Apr;59(4):1577-90.
Title: Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma.
Author: Fuchs, Bryan C|Hoshida, Yujin|Fujii, Tsutomu|Wei, Lan|Yamada, Suguru|Lauwers, Gregory Y|McGinn, Christopher M|DePeralta, Danielle K|Chen, Xintong|Kuroda, Toshihiko|Lanuti, Michael|Schmitt, Anthony D|Gupta, Supriya|Crenshaw, Andrew|Onofrio, Robert|Taylor,
PMID: 24677197
Journal: PLoS One. 2014 Apr 1;9(4):e93469.
Title: Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3beta pathways in vivo.
Author: Fullar, Alexandra|Baghy, Kornelia|Deak, Ferenc|Peterfia, Balint|Zsak, Yvonne|Tatrai, Peter|Schaff, Zsuzsa|Dudas, Jozsef|Kiss, Ibolya|Kovalszky, Ilona
PMID: 24691449
Journal: Cancer Sci. 2014 Jun;105(6):646-50.
Title: Impact of epidermal growth factor single-nucleotide polymorphism on recurrence of hepatocellular carcinoma after hepatectomy in patients with chronic hepatitis C virus infection.
Author: Yoshiya, Shohei|Fujimoto, Yukiko|Bekki, Yuki|Konishi, Hideyuki|Yamashita, Yo-Ichi|Ikegami, Toru|Yoshizumi, Tomoharu|Shirabe, Ken|Oda, Yoshinao|Maehara, Yoshihiko
PMID: 24703510
Journal: Asian Pac J Cancer Prev. 2014;15(5):1961-70.
Title: PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation.
Author: Fan, Fang-Tian|Shen, Cun-Si|Tao, Li|Tian, Chao|Liu, Zhao-Guo|Zhu, Zhi-Jie|Liu, Yu-Ping|Pei, Chang-Song|Wu, Hong-Yan|Zhang, Lei|Wang, Ai-Yun|Zheng, Shi-Zhong|Huang, Shi-Le|Lu, Yin
PMID: 24716919
Journal: Cancer Growth Metastasis. 2014 Mar 23;7:1-8.
Title: TGF-beta Mediated Crosstalk Between Malignant Hepatocyte and Tumor Microenvironment in Hepatocellular Carcinoma.
Author: Gupta, Devendra Kumar|Singh, Neetu|Sahu, Dinesh Kumar
PMID: 24741325
Journal: Tumour Biol. 2014 Jul;35(7):7135-45.
Title: Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells.
Author: Zhang, Min|Zhang, Hai|Cheng, Shanyu|Zhang, Dengcai|Xu, Yan|Bai, Xiaoming|Xia, Shukai|Zhang, Li|Ma, Juan|Du, Mingzhan|Wang, Yipin|Wang, Jie|Chen, Meng|Leng, Jing
PMID: 24760275
Journal: Asian Pac J Cancer Prev. 2014;15(7):3045-50.
Title: Targeting EGFL7 expression through RNA interference suppresses renal cell carcinoma growth by inhibiting angiogenesis.
Author: Xu, Han-Feng|Chen, Lei|Liu, Xian-Dong|Zhan, Yun-Hong|Zhang, Hui-Hui|Li, Qing|Wu, Bin
PMID: 24815445
Journal: Cancer Biomark. 2014;14(2-3):177-84.
Title: The prognostic value of the Na(+)/ H(+) exchanger regulatory factor 1 (NHERF1) protein in cancer.
Author: Saponaro, Concetta|Malfettone, Andrea|Dell'Endice, Teresa Stefania|Brunetti, Anna Elisabetta|Achimas-Cadariu, Patriciu|Paradiso, Angelo|Mangia, Anita
PMID: 24878819
Journal: Tumour Biol. 2014 Sep;35(9):8893-901.
Title: Activated macrophages down-regulate expression of E-cadherin in hepatocellular carcinoma cells via NF-kappaB/Slug pathway.
Author: Wang, Xianteng|Wang, Hao|Li, Guosheng|Song, Yonghong|Wang, Shurong|Zhu, Faliang|Guo, Chun|Zhang, Lining|Shi, Yongyu
PMID: 24894673
Journal: Biomed Res Int. 2014;2014:384121.
Title: Synergistic effect of MiR-146a mimic and cetuximab on hepatocellular carcinoma cells.
Author: Huang, Suning|He, Rongquan|Rong, Minhua|Dang, Yiwu|Chen, Gang
PMID: 24895573
Journal: Expert Rev Gastroenterol Hepatol. 2014 Nov;8(8):875-85.
Title: The role of targeted therapy for gastrointestinal tumors.
Author: Rolfo, Christian|Bronte, Giuseppe|Sortino, Giovanni|Papadimitriou, Konstantinos|Passiglia, Francesco|Fiorentino, Eugenio|Marogy, Ghada|Russo, Antonio|Peeters, Marc
PMID: 24957206
Journal: J BUON. 2014 Apr-Jun;19(2):412-8.
Title: Celastrol enhanced the anticancer effect of lapatinib in human hepatocellular carcinoma cells in vitro.
Author: Yan, Yan-yan|Guo, Yan|Zhang, Wei|Ma, Cun-gen|Zhang, Yan-xia|Wang, Chen|Wang, Hai-xia
PMID: 24965400
Journal: Bioorg Med Chem Lett. 2014 Sep 15;24(18):4472-4476.
Title: Design, synthesis and molecular modeling of biquinoline-pyridine hybrids as a new class of potential EGFR and HER-2 kinase inhibitors.
Author: Sangani, Chetan B|Makawana, Jigar A|Duan, Yong-Tao|Yin, Yong|Teraiya, Shashikant B|Thumar, Nilesh J|Zhu, Hai-Liang
PMID: 25172421
Journal: Asian Pac J Cancer Prev. 2014;15(19):8069-73.
Title: Crosstalk between EGFR and p53 in hepatocellular carcinoma.
Author: Cioca, Andreea|Cimpean, Anca|Ceausu, Raluca|Fit, Ana-Maria|Zaharie, Teodor|Al-Hajjar, Nadim|Puia, Vlad|Raica, Marius
PMID: 25338986
Journal: Front Endocrinol (Lausanne). 2014 Dec 18;5:218.
Title: Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice.
Author: Fan, Yong|Fang, Xin|Tajima, Asako|Geng, Xuehui|Ranganathan, Sarangarajan|Dong, Henry|Trucco, Massimo|Sperling, Mark A
PMID: 25566190
Journal: Liver Int. 2015 Apr;35(4):1416-29.
Title: Mannose-mediated inhibitory effects of PA-MSHA on invasion and metastasis of hepatocellular carcinoma via EGFR/Akt/IkappaBbeta/NF-kappaB pathway.
Author: Li, Tao|Dong, Zhao-Ru|Guo, Zong-Yi|Wang, Cheng-Hao|Zhi, Xu-Ting|Zhou, Jian-Wei|Li, Deng-Ke|Chen, Ze-Ting|Chen, Zhi-Qiang|Hu, San-Yuan
PMID: 25066210
Journal: Hepatology. 2015 Feb;61(2):613-26.
Title: Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.
Author: Stiedl, Patricia|McMahon, Robert|Blaas, Leander|Stanek, Victoria|Svinka, Jasmin|Grabner, Beatrice|Zollner, Gernot|Kessler, Sonja M|Claudel, Thierry|Muller, Mathias|Mikulits, Wolfgang|Bilban, Martin|Esterbauer, Harald|Eferl, Robert|Haybaeck, Johannes|Traun
PMID: 25179284
Journal: Invest New Drugs. 2015 Feb;33(1):128-37.
Title: A phase I and pharmacokinetic study of ganetespib (STA-9090) in advanced hepatocellular carcinoma.
Author: Goyal, Lipika|Wadlow, Raymond C|Blaszkowsky, Lawrence S|Wolpin, Brian M|Abrams, Thomas A|McCleary, Nadine Jackson|Sheehan, Susan|Sundaram, Eamala|Karol, Michael D|Chen, John|Zhu, Andrew X
PMID: 25248753
Journal: Mol Med Rep. 2015 Jan;11(1):712-8.
Title: Reactive oxygen species-mediated activation of the Src-epidermal growth factor receptor-Akt signaling cascade prevents bortezomib-induced apoptosis in hepatocellular carcinoma cells.
Author: Hou, Jinlin|Cui, Anguo|Song, Peiying|Hua, Hui|Luo, Ting|Jiang, Yangfu
PMID: 25338626
Journal: Oncotarget. 2015 Feb 10;6(4):2180-92.
Title: gamma-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1alpha/VEGF pathways under hypoxic condition.
Author: Xiao, Heng|Tong, Rongliang|Ding, Chaofeng|Lv, Zhen|Du, Chengli|Peng, Chuanhui|Cheng, Shaobing|Xie, Haiyang|Zhou, Lin|Wu, Jian|Zheng, Shusen
PMID: 25537504
Journal: Am J Cancer Res. 2014 Dec 15;5(1):396-410. eCollection 2015.
Title: Epidermal growth factor receptor pathway polymorphisms and the prognosis of hepatocellular carcinoma.
Author: Wang, Wenjia|Ma, Xiao-Pin|Shi, Zhuqing|Zhang, Pengyin|Ding, Dong-Lin|Huang, Hui-Xing|Saiyin, Hexi Ge|Chen, Tao-Yang|Lu, Pei-Xin|Wang, Neng-Jin|Yu, Hongjie|Sun, Jielin|Zheng, S Lilly|Yu, Long|Xu, Jianfeng|Jiang, De-Ke
PMID: 25628948
Journal: Discov Med. 2015 Jan;19(102):7-14.
Title: Novel molecular targets for diagnosis and treatment of hepatocellular carcinoma.
Author: Ma, Lifang|Ji, Lijuan|Yu, Yongchun|Wang, Jiayi
PMID: 25636956
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Oncotarget. 2015 Mar 20;6(8):5650-65.
Title: Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling.
Author: Huang, Miao-Juei|Hu, Rey-Heng|Chou, Chih-Hsing|Hsu, Chia-Lang|Liu, Ya-Wen|Huang, John|Hung, Ji-Shiang|Lai, I-Rue|Juan, Hsueh-Fen|Yu, Sung-Liang|Wu, Yao-Ming|Huang, Min-Chuan
PMID: 25730904
Journal: Sci Rep. 2015 Mar 6;5:8812.
Title: Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis.
Author: McKee, Chad|Sigala, Barbara|Soeda, Junpei|Mouralidarane, Angelina|Morgan, Maelle|Mazzoccoli, Gianluigi|Rappa, Francesca|Cappello, Francesco|Cabibi, Daniela|Pazienza, Valerio|Selden, Claire|Roskams, Tania|Vinciguerra, Manlio|Oben, Jude A
PMID: 25744849
Journal: Mol Med Rep. 2015 Jul;12(1):1421-8.
Title: Enoyl-coenzyme A hydratase short chain 1 silencing attenuates the proliferation of hepatocellular carcinoma by inhibiting epidermal growth factor signaling in vitro and in vivo.
Author: Lin, Bi-Yun|Xiao, Chuan-Xing|Zhao, Wen-Xiu|Xiao, Li|Chen, Xu|Li, Ping|Wang, Xiao-Min
PMID: 25760819
Journal: BMC Genomics. 2015 Feb 25;16:124.
Title: Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events.
Author: Borlak, Jurgen|Singh, Prashant|Gazzana, Giuseppe
PMID: 25872475
Journal: J Gen Virol. 2015 Aug;96(8):2133-44.
Title: Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction.
Author: Igloi, Zsofia|Kazlauskas, Arunas|Saksela, Kalle|Macdonald, Andrew|Mankouri, Jamel|Harris, Mark
PMID: 25872741
Journal: BMC Cancer. 2015 May 10;15:389.
Title: The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated alpha2M.
Author: Zhao, Song|Li, Hongdan|Wang, Qingjun|Su, Chang|Wang, Guan|Song, Huijuan|Zhao, Liang|Luan, Zhidong|Su, Rongjian
PMID: 25958313
Journal: Best Pract Res Clin Gastroenterol. 2015 Apr;29(2):345-53.
Title: Systemic therapy of cholangiocarcinoma: From chemotherapy to targeted therapies.
Author: Schweitzer, N|Vogel, A
PMID: 25966433
Journal: Am J Cancer Res. 2015 Jan 15;5(2):702-13. eCollection 2015.
Title: Dynamin2 downregulation delays EGFR endocytic trafficking and promotes EGFR signaling and invasion in hepatocellular carcinoma.
Author: Gong, Chaojie|Zhang, Jubo|Zhang, Lan|Wang, Yingcong|Ma, Hui|Wu, Weizhong|Cui, Jiefeng|Wang, Yanhong|Ren, Zhenggang
PMID: 25973308
Journal: Oncotarget. 2015 Jun 30;6(18):16507-16.
Title: Nuclear EGFR impairs ASPP2-p53 complex-induced apoptosis by inducing SOS1 expression in hepatocellular carcinoma.
Author: Liu, Kai|Jiang, Tao|Ouyang, Yabo|Shi, Ying|Zang, Yunjin|Li, Ning|Lu, Shichun|Chen, Dexi
PMID: 25980493
Journal: PLoS One. 2015 May 22;10(5):e0128159.
Title: The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma.
Author: Steinway, Steven N|Dang, Hien|You, Hanning|Rountree, C Bart|Ding, Wei
PMID: 26000702
Journal: Genomics. 2015 Aug;106(2):71-5.
Title: Discrepancies between the K-ras mutational status of primary colorectal cancers and corresponding liver metastases are found in codon 13.
Author: Kawamata, Hiroshi|Yamashita, Keishi|Kojo, Ken|Ushiku, Hideki|Ooki, Akira|Watanabe, Masahiko
PMID: 26026309
Journal: Discov Med. 2015 May;19(106):333-41.
Title: Lower serum soluble-EGFR is a potential biomarker for metastasis of HCC demonstrated by N-glycoproteomic analysis.
Author: Hu, Heng|Gao, Lingling|Wang, Cun|Li, Yan|Ma, Huiying|Chen, Long|Qin, Jie|Liu, Binbin|Liu, Yinkun|Liang, Chunmin
PMID: 26105696
Journal: Cancer Sci. 2015 Sep;106(9):1143-52.
Title: Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.
Author: Okada, Hikari|Honda, Masao|Campbell, Jean S|Takegoshi, Kai|Sakai, Yoshio|Yamashita, Taro|Shirasaki, Takayoshi|Takabatake, Riuta|Nakamura, Mikiko|Tanaka, Takuji|Kaneko, Shuichi
PMID: 26122702
Journal: Nanomedicine (Lond). 2015 Jul;10(12):1863-79.
Title: The promotion of salinomycin delivery to hepatocellular carcinoma cells through EGFR and CD133 aptamers conjugation by PLGA nanoparticles.
Author: Jiang, Jianxin|Chen, Huaiwen|Yu, Chao|Zhang, Yingying|Chen, Meiyuan|Tian, She|Sun, Chengyi
PMID: 26139123
Journal: PLoS One. 2015 Jul 6;10(7):e0132319.
Title: Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes.
Author: Li, Zhen|Zheng, Weiling|Li, Hankun|Li, Caixia|Gong, Zhiyuan
PMID: 26147004
Journal: Pathol Res Pract. 2015 Sep;211(9):665-70.
Title: Morphological aspects of the hepatic response to neoadjuvant therapy.
Author: Fernandez-Acenero, M J|Cortes-Guiral, D|Munoz, L Estrada|Martinez-Useros, J|Pastor-Idoate, C
PMID: 26163186
Journal: PLoS One. 2015 Jul 29;10(7):e0133081.
Title: BAI1-Associated Protein 2-Like 1 (BAIAP2L1) Is a Potential Biomarker in Ovarian Cancer.
Author: Chao, Angel|Tsai, Chia-Lung|Jung, Shih-Ming|Chuang, Wei-Chi|Kao, Chieh|Hsu, An|Chen, Shun-Hua|Lin, Chiao-Yun|Lee, Yi-Chao|Lee, Yun-Shien|Wang, Tzu-Hao|Wang, Hsin-Shih|Lai, Chyong-Huey
PMID: 26222696
Journal: Anticancer Drugs. 2015 Oct;26(9):1004-7.
Title: A significant response to sorafenib in a woman with advanced lung adenocarcinoma and a BRAF non-V600 mutation.
Author: Sereno, Maria|Moreno, Victor|Moreno Rubio, Juan|Gomez-Raposo, Cesar|Garcia Sanchez, Sagrario|Hernandez Jusdado, Rebeca|Falagan, Sandra|Zambrana Tebar, Francisco|Casado Saenz, Enrique
PMID: 26237499
Journal: Cancer Lett. 2015 Nov 1;368(1):126-34.
Title: Matrine derivative WM130 inhibits hepatocellular carcinoma by suppressing EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author: Qian, Liqiang|Liu, Yan|Xu, Yang|Ji, Weidan|Wu, Qiuye|Liu, Yongjing|Gao, Quangen|Su, Changqing
PMID: 26259512
Journal: Asian Pac J Trop Med. 2015 Jul;8(7):560-4.
Title: Anti-tumor effect of LTA combined with 5-FU on H22 tumor bearing mice.
Author: Wang, Bin|Lei, Chang-Jiang|Wu, Rong|Li, Lei|Deng, Chun-Mei|Chen, Wen-Xia|Hu, Fu-Rong|Long, Hao-Cheng|Tao, Ze-Zhang|Zeng, Cheng|Huang, Jian-Bin|Chen, Chun-Zhou|Ren, De-Fa
PMID: 26276288
Journal: APMIS. 2015 Oct;123(10):823-31.
Title: Impact of epidermal growth factor receptor and transforming growth factor-alpha on hepatitis C virus-induced hepatocarcinogenesis.
Author: Badawy, Afkar Abdel-Ghany|El-Hindawi, Ali|Hammam, Olfat|Moussa, Mona|Gabal, Samia|Said, Noha
PMID: 26279457
Journal: Chem Biol Interact. 2015 Dec 5;242:107-22.
Title: Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells.
Author: Bhullar, Khushwant S|Jha, Amitabh|Rupasinghe, H P Vasantha
PMID: 26409325
Journal: Am J Physiol Gastrointest Liver Physiol. 2015 Dec 15;309(12):G942-54.
Title: Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.
Author: Scheving, Lawrence A|Zhang, Xiuqi|Stevenson, Mary C|Weintraub, Michael A|Abbasi, Annam|Clarke, Andrea M|Threadgill, David W|Russell, William E
PMID: 26492920
Journal: PLoS One. 2015 Dec 4;10(12):e0143830.
Title: Additive Anti-Tumor Effects of Lovastatin and Everolimus In Vitro through Simultaneous Inhibition of Signaling Pathways.
Author: Nolting, Svenja|Maurer, Julian|Spottl, Gerald|Aristizabal Prada, Elke Tatjana|Reuther, Clemens|Young, Karen|Korbonits, Marta|Goke, Burkhard|Grossman, Ashley|Auernhammer, Christoph J
PMID: 26636335
Journal: Rinsho Byori. 2015 Sep;63(9):1091-102.
Title: [Alternative Splicing Detection as a Biomarker for Cancer Diagnosis: A Novel Progressive Mechanism of Acute Lymphoblastic Leukemia with Alternative Splicing as a Biomarker Candidate].
Author: Kitamura, Kouichi|Matsushita, Kazuyuki|Kobayashi, Souhei|Ishige, Takayuki|Semba, Toshihisa|Kimura, Asako|Kazami, Takahiro|Ohyama, Masayuki|Itoga, Sakae|Beppu, Minako|Nishimura, Motoi|Satoh, Mamoru|Nomura, Fumio
PMID: 26731899
Journal: ACS Infect Dis. 2015 Sep 11;1(9):420-7.
Title: Targeting Viral Entry for Treatment of Hepatitis B and C Virus Infections.
Author: Colpitts, Che C|Verrier, Eloi R|Baumert, Thomas F
PMID: 27617925
Journal: Mol Carcinog. 2016 Jul;55(7):1138-49.
Title: Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model.
Author: Sur, Subhayan|Pal, Debolina|Banerjee, Kaustav|Mandal, Suvra|Das, Ashes|Roy, Anup|Panda, Chinmay Kumar
PMID: 26154024
Journal: Tumour Biol. 2016 Jan;37(1):1079-89.
Title: The long noncoding RNA, EGFR-AS1, a target of GHR, increases the expression of EGFR in hepatocellular carcinoma.
Author: Qi, Hao-Long|Li, Chang-Sheng|Qian, Chong-Wei|Xiao, Yu-Sha|Yuan, Yu-Feng|Liu, Quan-Yan|Liu, Zhi-Su
PMID: 26271667
Journal: Tumour Biol. 2016 Feb;37(2):2527-35.
Title: Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma.
Author: Dang, Zheng|Shangguan, Jianying|Zhang, Chao|Hu, Peng|Ren, Yanshun|Lv, Zhicheng|Xiang, Hongjun|Wang, Xianghui
PMID: 26386721
Journal: J Nutr Biochem. 2016 Jan;27:32-42.
Title: Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways.
Author: Sur, Subhayan|Pal, Debolina|Mandal, Syamsundar|Roy, Anup|Panda, Chinmay Kumar
PMID: 26386739
Journal: Oncotarget. 2016 Jan 5;7(1):266-78.
Title: MicroRNA-107: a novel promoter of tumor progression that targets the CPEB3/EGFR axis in human hepatocellular carcinoma.
Author: Zou, Chen-Dan|Zhao, Wei-Ming|Wang, Xiao-Na|Li, Qiang|Huang, Hui|Cheng, Wan-Peng|Jin, Jian-Feng|Zhang, He|Wu, Ming-Juan|Tai, Sheng|Zou, Chao-Xia|Gao, Xu
PMID: 26497556
Journal: J Surg Oncol. 2016 Jan;113(1):55-61.
Title: Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options.
Author: Ang, Celina|Miura, John T|Gamblin, T Clark|He, Ruth|Xiu, Joanne|Millis, Sherri Z|Gatalica, Zoran|Reddy, Sandeep K|Yee, Nelson S|Abou-Alfa, Ghassan K
PMID: 26661118
Journal: Tumour Biol. 2016 Jul;37(7):9691-8.
Title: Tumour-suppressive role of PTPN13 in hepatocellular carcinoma and its clinical significance.
Author: Zhan, Hao|Jiang, Jiahao|Luo, Chubin|Sun, Qiman|Ke, Aiwu|Sun, Chao|Hu, Jinwu|Hu, Zhiqiang|Hu, Bo|Zhu, Kai|Fan, Jia|Zhou, Jian|Huang, Xiaowu
PMID: 26801674
Journal: J Cancer. 2016 Mar 20;7(6):671-80.
Title: Sex Difference of Egfr Expression and Molecular Pathway in the Liver: Impact on Drug Design and Cancer Treatments?
Author: Wang, Lishi|Xiao, Jianqi|Gu, Weikuan|Chen, Hong
PMID: 27076848
Journal: Am J Transl Res. 2016 Apr 15;8(4):1799-812. eCollection 2016.
Title: Genome-wide association study identified PLCE1- rs2797992 and EGFR- rs6950826 were associated with TP53 expression in the HBV-related hepatocellular carcinoma of Chinese patients in Guangxi.
Author: Liao, Xiwen|Han, Chuangye|Qin, Wei|Liu, Xiaoguang|Yu, Long|Lu, Sicong|Chen, Zhiwei|Zhu, Guangzhi|Su, Hao|Mo, Zengnan|Qin, Xue|Peng, Tao
PMID: 27186304
Journal: Oncotarget. 2016 Jun 28;7(26):39931-39944.
Title: Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
Author: Gale, Molly|Sayegh, Joyce|Cao, Jian|Norcia, Michael|Gareiss, Peter|Hoyer, Denton|Merkel, Jane S|Yan, Qin
PMID: 27224921
Journal: Oncotarget. 2016 Jul 19;7(29):45302-45316.
Title: EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway.
Author: Wang, Lumin|Sun, Hongfei|Wang, Xiaofei|Hou, Ni|Zhao, Lingyu|Tong, Dongdong|He, Kang|Yang, Yang|Song, Tusheng|Yang, Jun|Huang, Chen
PMID: 27244890
Journal: Cancer Res. 2016 Aug 15;76(16):4887-96.
Title: (Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression.
Author: Nguyen, Charles B|Kotturi, Hari|Waris, Gulam|Mohammed, Altaf|Chandrakesan, Parthasarathy|May, Randal|Sureban, Sripathi|Weygant, Nathaniel|Qu, Dongfeng|Rao, Chinthalapally V|Dhanasekaran, Danny N|Bronze, Michael S|Houchen, Courtney W|Ali, Naushad
PMID: 27287718
Journal: ACS Appl Mater Interfaces. 2016 Aug 3;8(30):19228-37.
Title: iRGD-Decorated Polymeric Nanoparticles for the Efficient Delivery of Vandetanib to Hepatocellular Carcinoma: Preparation and in Vitro and in Vivo Evaluation.
Author: Wang, Jianguo|Wang, Hangxiang|Li, Jie|Liu, Zhikun|Xie, Haiyang|Wei, Xuyong|Lu, Di|Zhuang, Runzhou|Xu, Xiao|Zheng, Shusen
PMID: 27381493
Journal: Cell Biol Toxicol. 2016 Dec;32(6):499-511.
Title: Actinidia chinensis Planch root extract (acRoots) inhibits hepatocellular carcinoma progression by inhibiting EP3 expression.
Author: Fang, Tingting|Hou, Jiayun|He, Mingyan|Wang, Lingyan|Zheng, Minghuan|Wang, Xiangdong|Xia, Jinglin
PMID: 27475644
Journal: Sci Rep. 2016 Aug 9;6:31237.
Title: EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma.
Author: Han, Chuangye|Liao, Xiwen|Qin, Wei|Yu, Long|Liu, Xiaoguang|Chen, Gang|Liu, Zhengtao|Lu, Sicong|Chen, Zhiwei|Su, Hao|Zhu, Guangzhi|Lu, Zili|Liu, Zhiming|Qin, Xue|Gui, Ying|Mo, Zengnan|Li, Lequn|Peng, Tao
PMID: 27502069
Journal: J Agric Food Chem. 2016 Sep 21;64(37):7002-13.
Title: Repression of Human Hepatocellular Carcinoma Growth by Regulating Met/EGFR/VEGFR-Akt/NF-kappaB Pathways with Theanine and Its Derivative, (R)-2-(6,8-Dibromo-2-oxo-2H-chromene-3-carboxamido)-5-(ethylamino)-5-oxopentanoic Ethyl Ester (DTBrC).
Author: Zhang, Guoying|Li, Zheng|Wan, Xiaochun|Zhang, Ying|Zhu, Rongqin|Liu, Zhenzhen|Ji, Dexin|Zhang, Huarong|Wu, Fei|Tian, Huihui|Liu, Kun|Wu, Benhao
PMID: 27569455
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: Biomed Opt Express. 2016 Aug 1;7(9):3163-3169.
Title: In vivo fluorescence imaging of hepatocellular carcinoma xenograft using near-infrared labeled epidermal growth factor receptor (EGFR) peptide.
Author: Li, Z|Zhou, Q|Zhou, J|Duan, X|Zhu, J|Wang, T D
PMID: 27699089
Journal: Photoacoustics. 2016 Apr 22;4(2):43-54.
Title: In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft.
Author: Zhou, Quan|Li, Zhao|Zhou, Juan|Joshi, Bishnu P|Li, Gaoming|Duan, Xiyu|Kuick, Rork|Owens, Scott R|Wang, Thomas D
PMID: 27766208
Journal: Am J Transl Res. 2016 Nov 15;8(11):4670-4681. eCollection 2016.
Title: eIF5A2 is an alternative pathway for cell proliferation in cetuximab-treated epithelial hepatocellular carcinoma.
Author: Xue, Fei|Liu, Yanhui|Chu, Haoyuan|Wen, Yu|Yan, Lei|Tang, Qiang|Xiao, Erhui|Zhang, Dongyi|Zhang, Hongwei
PMID: 27904670
Journal: Abdom Radiol (NY). 2017 Feb;42(2):451-459.
Title: Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90.
Author: Magnetta, Michael J|Ghodadra, Anish|Lahti, Steven J|Xing, Minzhi|Zhang, Di|Kim, Hyun S
PMID: 27600383
Journal: Cancer Res. 2017 Jan 15;77(2):579-589.
Title: SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor.
Author: Zheng, Li-Sheng|Yang, Jun-Ping|Cao, Yun|Peng, Li-Xia|Sun, Rui|Xie, Ping|Wang, Meng-Yao|Meng, Dong-Fang|Luo, Dong-Hua|Zou, Xiong|Chen, Ming-Yuan|Mai, Hai-Qiang|Guo, Ling|Guo, Xiang|Shao, Jian-Yong|Huang, Bi-Jun|Zhang, Wei|Qian, Chao-Nan
PMID: 27671677
Journal: Aliment Pharmacol Ther. 2017 Jan;45(1):150-159.
Title: Do directly acting antiviral agents for HCV increase the risk of hepatic decompensation and decline in renal function? Results from ERCHIVES.
Author: Butt, A A|Ren, Y|Marks, K|Shaikh, O S|Sherman, K E
PMID: 27813162
Journal: Mol Carcinog. 2017 Apr;56(4):1302-1311.
Title: TGFbeta signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells.
Author: Ungerleider, Nathan|Han, Chang|Zhang, Jinqiang|Yao, Lu|Wu, Tong
PMID: 27862334
Journal: Oncotarget. 2017 Jan 3;8(1):915-932.
Title: Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways.
Author: Yang, Jianhong|Pei, Heying|Luo, Hong|Fu, Afu|Yang, Hansuo|Hu, Jia|Zhao, Chengjian|Chai, LuLu|Chen, Xiang|Shao, Ximing|Wang, Chunyu|Wu, Wenshuang|Wan, Li|Ye, Haoyu|Qiu, Qiang|Peng, Aihua|Wei, Yuquan|Yang, Li|Chen, Lijuan
PMID: 27906672
Journal: Cancer Lett. 2017 Mar 1;388:73-84.
Title: Neurotensin regulation induces overexpression and activation of EGFR in HCC and restores response to erlotinib and sorafenib.
Author: Wu, Zherui|Galmiche, Antoine|Liu, Jin|Stadler, Nicolas|Wendum, Dominique|Segal-Bendirdjian, Evelyne|Paradis, Valerie|Forgez, Patricia
PMID: 27914862
Journal: Cancer Lett. 2017 Mar 28;389:1-10.
Title: CD133 confers cancer stem-like cell properties by stabilizing EGFR-AKT signaling in hepatocellular carcinoma.
Author: Jang, Jae-Woo|Song, Yeonhwa|Kim, Se-Hyuk|Kim, Jin-Sun|Kim, Kang Mo|Choi, Eun Kyung|Kim, Joon|Seo, Haeng Ran
PMID: 28034805
Journal: J Biol Chem. 2017 Feb 24;292(8):3186-3200.
Title: Loss of N-Acetylgalactosaminyltransferase-4 Orchestrates Oncogenic MicroRNA-9 in Hepatocellular Carcinoma.
Author: Liu, Yidong|Liu, Haiou|Yang, Liu|Wu, Qian|Liu, Weisi|Fu, Qiang|Zhang, Weijuan|Zhang, Haijian|Xu, Jiejie|Gu, Jianxin
PMID: 28062574
Journal: Oncotarget. 2017 Feb 21;8(8):13909-13916.
Title: Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach.
Author: Zhen, Cheng|Zhu, Caizhong|Chen, Haoyang|Xiong, Yiru|Tan, Junyuan|Chen, Dong|Li, Jin
PMID: 28108733
Journal: Oncogene. 2017 Jun 15;36(24):3464-3476.
Title: The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
Author: Hermanns, C|Hampl, V|Holzer, K|Aigner, A|Penkava, J|Frank, N|Martin, D E|Maier, K C|Waldburger, N|Roessler, S|Goppelt-Struebe, M|Akrap, I|Thavamani, A|Singer, S|Nordheim, A|Gudermann, T|Muehlich, S
PMID: 28114277
Journal: Dig Liver Dis. 2017 May;49(5):530-534.
Title: Long-term efficacy and safety of switching from lamivudine+adefovir to tenofovir disoproxil fumarate in virologically suppressed patients.
Author: Fasano, Massimo|Maggi, Paolo|Leone, Armando|Volpe, Anna|Fiore, Jose Ramon|Angarano, Gioacchino|Santantonio, Teresa Antonia
PMID: 28179096
Journal: Neoplasma. 2017;64(3):358-366.
Title: MicroRNA-1285 inhibits malignant biological behaviors of human pancreatic cancer cells by negative regulation of YAP1.
Author: Huang, H|Xiong, G|Shen, P|Cao, Z|Zheng, L|Zhang, T|Zhao, Y
PMID: 28253715
Journal: Anticancer Agents Med Chem. 2017;17(10):1389-1400.
Title: Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
Author: Bakr, Rania B|Mehany, Ahmed B M|Abdellatif, Khaled R A
PMID: 28270084
Journal: Eur J Med Chem. 2017 Apr 21;130:393-405.
Title: Design, synthesis, and biological evaluation of novel 4-anilinoquinazoline derivatives bearing amino acid moiety as potential EGFR kinase inhibitors.
Author: Zheng, You-Guang|Su, Jun|Gao, Cai-Yun|Jiang, Ping|An, Lin|Xue, Yun-Sheng|Gao, Jian|Liu, Yi
PMID: 28279846
Journal: J Cancer Res Clin Oncol. 2017 Jul;143(7):1337-1346.
Title: Incidence and outcomes of acute kidney injury in patients with hepatocellular carcinoma after liver transplantation.
Author: Chen, Xiaohong|Ding, Xiaoqiang|Shen, Bo|Teng, Jie|Zou, Jianzhou|Wang, Ting|Zhou, Jian|Chen, Nan|Zhang, Boheng
PMID: 28289896
Journal: Oncotarget. 2017 Mar 21;8(12):19354-19364.
Title: Secreted GRP78 activates EGFR-SRC-STAT3 signaling and confers the resistance to sorafeinib in HCC cells.
Author: Li, Rui|Yanjiao, Gu|Wubin, He|Yue, Wang|Jianhua, Huang|Huachuan, Zheng|Rongjian, Su|Zhidong, Luan
PMID: 28423613
Journal: Med Oncol. 2017 Jun;34(6):101.
Title: The identification of key genes and pathways in hepatocellular carcinoma by bioinformatics analysis of high-throughput data.
Author: Zhang, Chaoyang|Peng, Li|Zhang, Yaqin|Liu, Zhaoyang|Li, Wenling|Chen, Shilian|Li, Guancheng
PMID: 28432618
Journal: Oncotarget. 2017 Apr 18;8(16):27263-27276.
Title: SHP2 is induced by the HBx-NF-kappaB pathway and contributes to fibrosis during human early hepatocellular carcinoma development.
Author: Kang, Hyo Jeong|Chung, Dal-Hee|Sung, Chang Ohk|Yoo, Su Hyun|Yu, Eunsil|Kim, Nayoung|Lee, Sy-Hye|Song, Ji-Young|Kim, Chong Jai|Choi, Jene
PMID: 28460481
Journal: PLoS One. 2017 May 9;12(5):e0176562.
Title: Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation.
Author: Sorenson, Eric C|Khanin, Raya|Bamboat, Zubin M|Cavnar, Michael J|Kim, Teresa S|Sadot, Eran|Zeng, Shan|Greer, Jonathan B|Seifert, Adrian M|Cohen, Noah A|Crawley, Megan H|Green, Benjamin L|Klimstra, David S|DeMatteo, Ronald P
PMID: 28486549
Journal: Bioorg Med Chem. 2017 Jun 15;25(12):2956-2970.
Title: Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma.
Author: Elshaier, Yaseen A M M|Shaaban, Mohamed A|Abd El Hamid, Mohammed K|Abdelrahman, Mostafa H|Abou-Salim, Mahrous A|Elgazwi, Sara M|Halaweish, Fathi
PMID: 28487127
Journal: Sci Rep. 2017 Jul 11;7(1):5134.
Title: Hydrogen sulfide acts as a double-edged sword in human hepatocellular carcinoma cells through EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author: Wu, Dongdong|Li, Mengling|Tian, Wenke|Wang, Shuaiwei|Cui, Longzhen|Li, Hui|Wang, Huijuan|Ji, Ailing|Li, Yanzhang
PMID: 28698660
Journal: Sci Rep. 2017 Jul 19;7(1):5851.
Title: Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase.
Author: Srivastava, Jitendra Kumar|Pillai, Girinath G|Bhat, Hans Raj|Verma, Amita|Singh, Udaya Pratap
PMID: 28724908
Journal: Oncol Res. 2017 Jul 21.
Title: MicroRNA-374a Promotes Hepatocellular Carcinoma Cell Proliferation by Targeting Mitogen-Inducible Gene-6 (MIG-6).
Author: Li, Hui|Chen, Huicheng|Wang, Haibin|Dong, Yilong|Yin, Min|Zhang, Liang|Wei, Jia
PMID: 28734040
Journal: Biomaterials. 2017 Oct;143:1-16.
Title: Simultaneous inhibition of growth and metastasis of hepatocellular carcinoma by co-delivery of ursolic acid and sorafenib using lactobionic acid modified and pH-sensitive chitosan-conjugated mesoporous silica nanocomplex.
Author: Zhao, Ruirui|Li, Tao|Zheng, Guirong|Jiang, Kai|Fan, Lulu|Shao, Jingwei
PMID: 28755539
Journal: J Virol. 2017 Sep 27;91(20). pii: JVI.00467-17.
Title: HRAS, EGFR, MET, and RON Genes Are Recurrently Activated by Provirus Insertion in Liver Tumors Induced by the Retrovirus Myeloblastosis-Associated Virus 2.
Author: Pecenka, Vladimir|Pajer, Petr|Karafiat, Vit|Kasparova, Petra|Dudlova, Jana|Dvorak, Michal
PMID: 28768863
Journal: Cancer Med. 2017 Sep;6(9):2042-2051.
Title: INST OX-05-024: first line gemcitabine, oxaliplatin, and erlotinib for primary hepatocellular carcinoma and bile duct cancers: a multicenter Phase II trial.
Author: Patt, Yehuda Z|Murad, Waheed|Fekrazad, Mohammed H|Baron, Ari D|Bansal, Pranshu|Boumber, Yanis|Steinberg, Kim|Lee, Sang-Joon|Bedrick, Ed|Du, Ruofei|Lee, Fa Chyi
PMID: 28801995
Journal: Mol Cancer. 2017 Sep 11;16(1):152.
Title: Cell-specific mechanisms of TMEM16A Ca(2+)-activated chloride channel in cancer.
Author: Wang, Hui|Zou, Liang|Ma, Ke|Yu, Jiankun|Wu, Huizhe|Wei, Minjie|Xiao, Qinghuan
PMID: 28893247
Journal: Sci Rep. 2017 Sep 13;7(1):11448.
Title: MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance.
Author: Awan, Faryal Mehwish|Naz, Anam|Obaid, Ayesha|Ikram, Aqsa|Ali, Amjad|Ahmad, Jamil|Naveed, Abdul Khaliq|Janjua, Hussnain Ahmed
PMID: 28904393
Journal: Sci Rep. 2017 Sep 14;7(1):11563.
Title: Inhibition of fucosylation by 2-fluorofucose suppresses human liver cancer HepG2 cell proliferation and migration as well as tumor formation.
Author: Zhou, Ying|Fukuda, Tomohiko|Hang, Qinglei|Hou, Sicong|Isaji, Tomoya|Kameyama, Akihiko|Gu, Jianguo
PMID: 28912543
Journal: Bioconjug Chem. 2017 Nov 15;28(11):2794-2803.
Title: Ultrasmall Paramagnetic Iron Oxide Nanoprobe Targeting Epidermal Growth Factor Receptor for In Vivo Magnetic Resonance Imaging of Hepatocellular Carcinoma.
Author: Chen, Yan|Zhou, Quan|Li, Xue|Wang, Fa|Heist, Kevin|Kuick, Rork|Owens, Scott R|Wang, Thomas D
PMID: 28972742
Journal: BMC Complement Altern Med. 2017 Oct 4;17(1):477.
Title: Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Author: Jiang, Qin|Yang, Manyi|Qu, Zhan|Zhou, Jixiang|Zhang, Qi
PMID: 28978315
Journal: Pathologe. 2017 Nov;38(Suppl 2):211-217.
Title: [Nuclear Her2 expression in hepatocytes in liver disease].
Author: Doring, P|Pilo, G M|Calvisi, D F|Dombrowski, F
PMID: 29018945
Journal: Front Med (Lausanne). 2017 Sep 28;4:164.
Title: Hepatoid Adenocarcinoma of the Stomach: A Challenging Diagnostic and Therapeutic Disease through a Case Report and Review of the Literature.
Author: Fakhruddin, Najla|Bahmad, Hisham F|Aridi, Tarek|Yammine, Yara|Mahfouz, Rami|Boulos, Fouad|Awada, Ahmad|Farhat, Fadi
PMID: 29034239
Journal: Korean J Anesthesiol. 2017 Oct;70(5):527-534.
Title: Effects of acute kidney injury after liver resection on long-term outcomes.
Author: Ishikawa, Seiji|Tanaka, Manami|Maruyama, Fumi|Fukagawa, Arisa|Shiota, Nobuhiro|Matsumura, Satoshi|Makita, Koshi
PMID: 29046772
Journal: Oncotarget. 2017 May 3;8(42):71736-71749.
Title: UBE2J2 promotes hepatocellular carcinoma cell epithelial-mesenchymal transition and invasion in vitro.
Author: Chen, Shaopeng|Tan, Ying|Deng, Haihua|Shen, Zhifa|Liu, Yanhong|Wu, Pan|Tan, Chunyan|Jiang, Yuyang
PMID: 29069742
Journal: Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title: Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author: Jung, Joohee|Kim, Jisup|Lim, Hyun Kyung|Kim, Kyoung Mee|Lee, Yun Sun|Park, Joon Seong|Yoon, Dong Sup
PMID: 29094026
Journal: Oncogene. 2017 Nov 30;36(48):6747-6748.
Title: Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway.
Author: Ding, D|Huang, H|Jiang, W|Yu, W|Zhu, H|Liu, J|Saiyin, H|Wu, J|Huang, H|Jiang, S|Yu, L
PMID: 29188822
Journal: Molecules. 2017 Dec 27;23(1). pii: molecules23010048.
Title: Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
Author: Alswah, Mohamed|Bayoumi, Ashraf H|Elgamal, Kamal|Elmorsy, Ahmed|Ihmaid, Saleh|Ahmed, Hany E A
PMID: 29280968
Journal: Technol Cancer Res Treat. 2017 Dec;16(6):1136-1149.
Title: Mir-452-3p: A Potential Tumor Promoter That Targets the CPEB3/EGFR Axis in Human Hepatocellular Carcinoma.
Author: Tang, Hui|Zhang, Jianwen|Yu, Zhenyu|Ye, Linsen|Li, Kun|Ding, Fan|Feng, Xiao|Meng, Wei
PMID: 29332449
Journal: Curr Cancer Drug Targets. 2018;18(5):430-441.
Title: The Role of Target Therapy in the Treatment of Gastrointestinal Noncolorectal Cancers: Clinical Impact and Cost Consideration.
Author: Berretta, Massimiliano|Romano, Carmela|Di Francia, Raffaele|De Diviitis, Chiara|Canzonieri, Vincenzo|Caraglia, Michele|Facchini, Gaetano|Nasti, Guglielmo
PMID: 28183250
Journal: Mol Carcinog. 2018 Jan;57(1):44-56.
Title: Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo.
Author: Zhang, Hui-Hui|Zhang, Ying|Cheng, Yan-Na|Gong, Fu-Lian|Cao, Zhan-Qi|Yu, Lu-Gang|Guo, Xiu-Li
PMID: 28833603
Journal: Int J Hyperthermia. 2018 Sep;34(6):812-823.
Title: Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma.
Author: Thompson, Scott M|Jondal, Danielle E|Butters, Kim A|Knudsen, Bruce E|Anderson, Jill L|Stokes, Matthew P|Jia, Xiaoying|Grande, Joseph P|Roberts, Lewis R|Callstrom, Matthew R|Woodrum, David A
PMID: 28954551
Journal: Mol Carcinog. 2018 Feb;57(2):201-215.
Title: Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through beta-catenin-EGFR-PI3K-Akt-mTOR signaling pathway.
Author: Zhang, Bin|Deng, Chao|Wang, Lei|Zhou, Fan|Zhang, Shu|Kang, Wei|Zhan, Ping|Chen, Juan|Shen, Shanshan|Guo, Huimin|Zhang, Ming|Wang, Yi|Zhang, Feng|Zhang, Wei|Xiao, Jiangqiang|Kong, Bo|Friess, Helmut|Zhuge, Yuzheng|Yan, Hongli|Zou, Xiaoping
PMID: 29027712
Journal: Int J Oncol. 2018 Jan;52(1):189-200.
Title: Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins.
Author: De Araujo, Raimundo F Jr|Pessoa, Jonas B|Cruz, Luis J|Chan, Alan B|De Castro Miguel, Emilio|Cavalcante, Romulo S|Brito, Gerly Anne C|Silva, Heloiza Fernada O|Gasparotto, Luiz H S|Guedes, Paulo M M|Araujo, Aurigena A
PMID: 29115423
Journal: Exp Mol Pathol. 2018 Apr;104(2):125-129.
Title: Expression of proteins upregulated in hepatocellular carcinoma in patients with alcoholic hepatitis (AH) compared to non-alcoholic steatohepatitis (NASH): An immunohistochemical analysis of candidate proteins.
Author: Lu, Jiajie George|Nguyen, Luan|Samadzadeh, Sara|Masouminia, Maryam|Mendoza, Alejandro|Sweeney, Owen|Tillman, Brittany|Afifyan, Nikoo|Morgan, Timothy|French, Barbara A|French, Samuel W
PMID: 29425759
Journal: N Biotechnol. 2018 Oct 25;45:113-122.
Title: Neuregulin 1 discovered as a cleavage target for the HCV NS3/4A protease by a microfluidic membrane protein array.
Author: Schwartz, Nika|Pellach, Michal|Glick, Yair|Gil, Reuven|Levy, Gahl|Avrahami, Dorit|Barbiro-Michaely, Efrat|Nahmias, Yaakov|Gerber, Doron
PMID: 29438748
Journal: Sci Rep. 2018 Feb 19;8(1):3287.
Title: Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers.
Author: Zhang, Lin|Zhang, Yuchen|Wong, Sunny H|Law, Priscilla T Y|Zhao, Shan|Yu, Jun|Chan, Matthew T V|Wu, William K K
PMID: 29459716
Journal: Steroids. 2018 Jun;134:78-87.
Title: The ER-alpha36/EGFR signaling loop promotes growth of hepatocellular carcinoma cells.
Author: You, Hui|Meng, Kun|Wang, Zhao-Yi
PMID: 29481815
Journal: Int J Mol Med. 2018 May;41(5):2813-2831.
Title: Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
Author: He, Rong-Quan|Wu, Pei-Rong|Xiang, Xue-Lian|Yang, Xia|Liang, Hai-Wei|Qiu, Xiao-Hui|Yang, Li-Hua|Peng, Zhi-Gang|Chen, Gang
PMID: 29484429
Journal: Oncologist. 2018 May;23(5):586-593.
Title: Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma.
Author: Ikeda, Sadakatsu|Tsigelny, Igor F|Skjevik, Age A|Kono, Yuko|Mendler, Michel|Kuo, Alexander|Sicklick, Jason K|Heestand, Gregory|Banks, Kimberly C|Talasaz, AmirAli|Lanman, Richard B|Lippman, Scott|Kurzrock, Razelle
PMID: 29487225
Journal: Clin Cancer Res. 2018 Jul 1;24(13):3204-3216.
Title: COX-2/PGE2 Axis Regulates HIF2alpha Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib Treatment.
Author: Dong, Xiao-Feng|Liu, Tian-Qi|Zhi, Xu-Ting|Zou, Jie|Zhong, Jing-Tao|Li, Tao|Mo, Xiang-Lan|Zhou, Wei|Guo, Wen-Wen|Liu, Xia|Chen, Yuan-Yuan|Li, Meng-Yang|Zhong, Xiao-Gang|Han, Ya-Min|Wang, Zhong-Hao|Dong, Zhao-Ru
PMID: 29514844
Journal: Signal Transduct Target Ther. 2018 Jan 26;3:3.
Title: The dual-inhibitory effect of miR-338-5p on the multidrug resistance and cell growth of hepatocellular carcinoma.
Author: Zhao, Yang|Chen, Jing|Wei, Wenxin|Qi, Xinming|Li, Chunzhu|Ren, Jin
PMID: 29527329
Journal: Mol Cell Biochem. 2018 Mar 12. pii: 10.1007/s11010-018-3341-9.
Title: A novel matrine derivative WM622 inhibits hepatocellular carcinoma by inhibiting PI3K/AKT signaling pathways.
Author: Sun, Xiao|Zhuo, Xiao-Bin|Hu, Yi-Ping|Zheng, Xuan|Zhao, Qing-Jie
PMID: 29532226
Journal: J Cell Mol Med. 2018 Jun;22(6):2981-2992.
Title: Integrated transcriptomic and proteomic analyses reveal a-lipoic acid-regulated cell proliferation via Grb2-mediated signalling in hepatic cancer cells.
Author: Yang, Lan|Wang, Xiliang|Xu, Juan|Wen, Ya|Zhang, Manqiao|Lu, Jingxiao|Wang, Rongfu|Sun, Xiaojuan
PMID: 29575431
Journal: Cell Physiol Biochem. 2018;46(1):226-237.
Title: The Effect of and Mechanism Underlying Autophagy in Hepatocellular Carcinoma Induced by CH12, a Monoclonal Antibody Directed Against Epidermal Growth Factor Receptor Variant III.
Author: Xu, Wen|Song, Fei|Wang, Biao|Li, Kesang|Tian, Mi|Yu, Min|Pan, Xiaorong|Shi, Bizhi|Liu, Jianwen|Gu, Jianren|Li, Zonghai|Jiang, Hua
PMID: 29587298
Journal: Oncogene. 2018 Jul;37(28):3894-3908.
Title: An EGFR ligand promotes EGFR-mutant but not KRAS-mutant lung cancer in vivo.
Author: Tomoshige, Koichi|Guo, Minzhe|Tsuchiya, Tomoshi|Fukazawa, Takuya|Fink-Baldauf, Iris M|Stuart, William D|Naomoto, Yoshio|Nagayasu, Takeshi|Maeda, Yutaka
PMID: 29662194
Journal: Anticancer Agents Med Chem. 2018 May 7. pii: ACAMC-EPUB-90231.
Title: HCC Specific Protein Network Involving Interactions of EGFR with A-Raf and Transthyretin: Experimental Analysis and Computational Biology Correlates.
Author: Ranjpour, Maryam|Katare, Deepshikha Pande|Wajid, Saima|Jain, Swatantra Kumar
PMID: 29732980
Journal: Mol Ther Nucleic Acids. 2018 Jun 1;11:494-507.
Title: miR372 Promotes Progression of Liver Cancer Cells by Upregulating erbB-2 through Enhancement of YB-1.
Author: Lin, Zhuojia|Lu, Yanan|Meng, Qiuyu|Wang, Chen|Li, Xiaonan|Yang, Yuxin|Xin, Xiaoru|Zheng, Qidi|Xu, Jie|Gui, Xin|Li, Tianming|Pu, Hu|Xiong, Wujun|Li, Jiao|Jia, Song|Lu, Dongdong
PMID: 29858084
Journal: Environ Toxicol. 2018 Jun 19.
Title: The protective mechanism of Nigella sativa against diethylnitrosamine-induced hepatocellular carcinoma through its antioxidant effect and EGFR/ERK1/2 signaling.
Author: Shahin, Y R|Elguindy, N M|Abdel Bary, A|Balbaa, M
PMID: 29923357
Journal: J Hepatol. 2018 Oct;69(4):840-850.
Title: Mutational landscape of a chemically-induced mouse model of liver cancer.
Author: Connor, Frances|Rayner, Tim F|Aitken, Sarah J|Feig, Christine|Lukk, Margus|Santoyo-Lopez, Javier|Odom, Duncan T
PMID: 29958939
Journal: Can J Physiol Pharmacol. 2018 Aug 8.
Title: Silencing non-SMC chromosome-associated polypeptide G inhibits proliferation and induces apoptosis in hepatocellular carcinoma cells.
Author: Liu, Kaikun|Li, Yumin|Yu, Bo|Wang, Furong|Mi, Taiyu|Zhao, Yongxun
PMID: 30089216
Journal: Ann Transl Med. 2018 Jul;6(14):285.
Title: Precision oncology in liver cancer.
Author: Sullivan, Kevin M|Kenerson, Heidi L|Pillarisetty, Venu G|Riehle, Kimberly J|Yeung, Raymond S
PMID: 30105235
Journal: Liver Int. 2018 Sep 4.
Title: P57-mediated autophagy promotes the efficacy of EGFR inhibitors in hepatocellular carcinoma.
Author: Li, Wen-Yuan|Li, Qing|Jing, Li|Wu, Tao|Han, Li-Li|Wang, Yu|Yu, Si-Zhe|Nan, Ke-Jun|Guo, Hui
PMID: 30178471
Journal: J Cell Physiol. 2018 Sep 10.
Title: Neratinib augments the lethality of [regorafenib + sildenafil].
Author: Booth, Laurence|Roberts, Jane L|Rais, Rumeesa|Cutler, Richard E Jr|Diala, Irmina|Lalani, Alshad S|Hancock, John F|Poklepovic, Andrew|Dent, Paul
PMID: 30203445
Journal: Breast Cancer Res. 2018 Sep 12;20(1):112.
Title: Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
Author: Gao, Pin|Wang, Xiang|Jin, Ying|Hu, Wenquan|Duan, Yajun|Shi, Aiping|Du, Ye|Song, Dong|Yang, Ming|Li, Sijie|Han, Bing|Zhao, Gang|Zhang, Hongquan|Fan, Zhimin|Miao, Qing Robert
PMID: 30208932
Journal: Oncol Rep. 2018 Oct 1.
Title: Capsaicin and sorafenib combination treatment exerts synergistic antihepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling.
Author: Dai, Ninggao|Ye, Ruifan|He, Qikuan|Guo, Pengyi|Chen, Hao|Zhang, Qiyu
PMID: 30272354
Journal: J Enzyme Inhib Med Chem. 2018 Dec;33(1):1516-1528.
Title: Benzofuran-appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies.
Author: Mphahlele, Malose J|Maluleka, Marole M|Aro, Abimbola|McGaw, Lyndy J|Choong, Yee Siew
PMID: 30274538
Journal: Bioorg Med Chem Lett. 2018 Oct 11. pii: S0960-894X(18)30806-0.
Title: Design, synthesis and evaluation of novel hybrids between 4-anilinoquinazolines and substituted triazoles as potent cytotoxic agents.
Author: Le-Nhat-Thuy, Giang|Dinh, Thuy Van|Pham-The, Hai|Nguyen Quang, Hung|Nguyen Thi, Nga|Dang Thi, Tuyet Anh|Hoang Thi, Phuong|Le Thi, Tu Anh|Nguyen, Ha Thanh|Nguyen Thanh, Phuong|Le Duc, Trung|Nguyen, Tuyen Van
PMID: 30337229
Journal: Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title: Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author: Del Carmen, Sofia|Sayagues, Jose Maria|Bengoechea, Oscar|Anduaga, Maria Fernanda|Alcazar, Jose Antonio|Gervas, Ruth|Garcia, Jacinto|Orfao, Alberto|Bellvis, Luis Munoz|Sarasquete, Maria Eugenia|Del Mar Abad, Maria
PMID: 30344942
Journal: Nanomedicine. 2018 Oct 21. pii: S1549-9634(18)30537-9.
Title: Smart nanoparticles assembled by endogenous molecules for siRNA delivery and cancer therapy via CD44 and EGFR dual-targeting.
Author: Liang, Yaoyao|Peng, Jiahui|Li, Ning|Yu-Wai-Man, Cynthia|Wang, Qian|Xu, Yuhong|Wang, Hongxia|Tagalakis, Aristides D|Du, Zixiu
PMID: 30352311