Primary Site >> Colorectal Cancer

Gene >> EGF

Journal: Surgery. 1985 Jun;97(6):696-700.
Title: Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice.
Author: Kingsnorth, A N|Abu-Khalaf, M|Ross, J S|Malt, R A
PMID: 3873715
Journal: Arch Surg. 1986 Nov;121(11):1242-7.
Title: Increased expression of the epidermal growth factor receptor on human colon carcinoma cells.
Author: Bradley, S J|Garfinkle, G|Walker, E|Salem, R|Chen, L B|Steele, G Jr
PMID: 3535739
Journal: J Surg Oncol. 1988 Jun;38(2):108-12.
Title: Adenylate cyclase activity and cyclic adenosine monophosphate levels in colon cancer lines and dermal fibroblasts and the effects of cholera toxin and epidermal growth factor.
Author: Nelson, R L|Holian, O
PMID: 2837611
Journal: Cancer Res. 1988 May 1;48(9):2469-74.
Title: Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose.
Author: Boyd, D D|Levine, A E|Brattain, D E|McKnight, M K|Brattain, M G
PMID: 3281751
Journal: Cancer Res. 1989 Apr 15;49(8):1948-53.
Title: Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line.
Author: Boyd, D|Brattain, M
PMID: 2539250
Journal: Cancer Res. 1989 May 1;49(9):2427-32.
Title: Examination of the effects of epidermal growth factor on the production of urokinase and the expression of the plasminogen activator receptor in a human colon cancer cell line.
Author: Boyd, D
PMID: 2539903
Journal: Klin Wochenschr. 1989 May 15;67(10):518-23.
Title: Epidermal growth factor receptors and epidermal growth factor-like activity in colorectal mucosa, adenomas and carcinomas.
Author: Rothbauer, E|Mann, K|Wiebecke, B|Borlinghaus, P|Lamerz, R|Pratschke, E|Kramling, H J|Pfeiffer, A
PMID: 2544769
Journal: Int J Cancer. 1989 Jul 15;44(1):110-5.
Title: Expression of TGF-alpha/EGF and TGF-beta receptors in human colon carcinoma cell lines.
Author: Murthy, U|Anzano, M A|Greig, R G
PMID: 2545633
Journal: Biochem Biophys Res Commun. 1989 Apr 14;160(1):317-24.
Title: Binding of epidermal growth factor by human colon carcinoma cell (Caco-2) monolayers.
Author: Hidalgo, I J|Kato, A|Borchardt, R T
PMID: 2785387
Journal: Cancer Res. 1989 Feb 15;49(4):816-20.
Title: Examination of urokinase protein/transcript levels and their relationship with laminin degradation in cultured colon carcinoma.
Author: Boyd, D|Ziober, B|Chakrabarty, S|Brattain, M
PMID: 2912554
Journal: J Clin Oncol. 1990 May;8(5):831-7.
Title: Epithelial tumor cells in bone marrow of patients with colorectal cancer: immunocytochemical detection, phenotypic characterization, and prognostic significance.
Author: Schlimok, G|Funke, I|Bock, B|Schweiberer, B|Witte, J|Riethmuller, G
PMID: 1692090
Journal: Virchows Arch B Cell Pathol Incl Mol Pathol. 1990;59(3):173-8.
Title: Expression of several growth factors and their receptor genes in human colon carcinomas.
Author: Ito, M|Yoshida, K|Kyo, E|Ayhan, A|Nakayama, H|Yasui, W|Ito, H|Tahara, E
PMID: 1980764
Journal: J Cancer Res Clin Oncol. 1990;116(2):121-31.
Title: Growth factors and oncogenes in human gastrointestinal carcinomas.
Author: Tahara, E
PMID: 2157713
Journal: Histochem J. 1990 Aug;22(8):426-32.
Title: Biotinylated epidermal growth factor: a useful tool for the histochemical analysis of specific binding sites.
Author: Kayser, K|Weisse, G|Gabius, H J|Hintze, T
PMID: 2228731
Journal: J Cell Biochem. 1990 Oct;44(2):69-79.
Title: Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha.
Author: Rodeck, U|Williams, N|Murthy, U|Herlyn, M
PMID: 2250044
Journal: Nihon Shokakibyo Gakkai Zasshi. 1990 May;87(5):1160-7.
Title: [Immunohistochemical studies on the expression of epidermal growth factor (EGF) in human colorectal cancers].
Author: Takemura, K|Obara, T|Okamura, K
PMID: 2384983
Journal: Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1656-60.
Title: Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors.
Author: Lee, M T|Liebow, C|Kamer, A R|Schally, A V
PMID: 1672042
Journal: Am J Physiol. 1991 Oct;261(4 Pt 1):G669-76.
Title: Effects of epidermal growth factor on diamine oxidase expression and cell growth in Caco-2 cells.
Author: Daniele, B|Quaroni, A
PMID: 1681737
Journal: Cancer Res. 1991 Mar 1;51(5):1452-9.
Title: Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient.
Author: Gross, M E|Zorbas, M A|Danels, Y J|Garcia, R|Gallick, G E|Olive, M|Brattain, M G|Boman, B M|Yeoman, L C
PMID: 1847663
Journal: J Cell Physiol. 1992 Feb;150(2):320-6.
Title: Identification of basic fibroblast growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines.
Author: New, B A|Yeoman, L C
PMID: 1310324
Journal: Radiat Res. 1992 Nov;132(2):263-8.
Title: Effects of partial hepatectomy on the growth characteristics and hypoxic fractions of xenografted DLD-2 human colon cancers.
Author: Leith, J T|Padfield, G|Michelson, S
PMID: 1438710
Journal: Mol Biol Cell. 1992 Nov;3(11):1235-43.
Title: Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line.
Author: Sizeland, A M|Burgess, A W
PMID: 1457828
Journal: Int J Cancer. 1992 Dec 2;52(6):978-86.
Title: Proliferation of human colon cancer cells: role of epidermal growth factor and transforming growth factor alpha.
Author: Huang, S|Trujillo, J M|Chakrabarty, S
PMID: 1459740
Journal: Oncology. 1992;49(5):381-5.
Title: Immunoreactive transforming growth factor-alpha and epidermal growth factor in colorectal adenomas and carcinomas.
Author: Tanaka, S|Imanishi, K|Haruma, K|Tsuda, T|Yoshihara, M|Sumii, K|Kajiyama, G
PMID: 1528573
Journal: Dis Colon Rectum. 1992 Apr;35(4):305-9.
Title: Sex steroid hormone receptors, epidermal growth factor receptor, and polyamines in human colorectal cancer.
Author: Di Leo, A|Linsalata, M|Cavallini, A|Messa, C|Russo, F
PMID: 1582349
Journal: Cell Signal. 1993 Nov;5(6):795-802.
Title: Epidermal growth factor increases 32P incorporation into phosphatidylcholine and protein kinase C activity in colon carcinoma cell line (HT29).
Author: Balogh, A|Keri, G|Teplan, I|Csuka, O
PMID: 8130082
Journal: J Biol Chem. 1993 Jun 25;268(18):13396-405.
Title: Epidermal growth factor induces serine phosphorylation of stathmin in a human colon carcinoma cell line (LIM 1215).
Author: Ji, H|Baldwin, G S|Burgess, A W|Moritz, R L|Ward, L D|Simpson, R J
PMID: 8514777
Journal: Ann Oncol. 1994 Mar;5(3):269-76.
Title: 5-Aza-2'-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells.
Author: Caraglia, M|Pinto, A|Correale, P|Zagonel, V|Genua, G|Leardi, A|Pepe, S|Bianco, A R|Tagliaferri, P
PMID: 7514437
Journal: Clin Biochem. 1994 Dec;27(6):485-9.
Title: Urinary epidermal growth factor receptor-binding growth factors in patients with cancers of the digestive tract.
Author: Chuang, L Y|Hung, W C|Yang, M L|Chang, C C|Tsai, J F
PMID: 7697894
Journal: Am J Physiol. 1994 Dec;267(6 Pt 1):G1101-7.
Title: Caco-2 cells express type I interleukin-1 receptors: ligand binding enhances proliferation.
Author: Varilek, G W|Neil, G A|Bishop, W P
PMID: 7810657
Journal: Gut. 1994 Dec;35(12):1742-6.
Title: Divergent effects of epidermal growth factor and calcipotriol on human rectal cell proliferation.
Author: Thomas, M G|Brown, G R|Alison, M R|Williamson, R C
PMID: 7829012
Journal: Pathol Int. 1994 Feb;44(2):124-30.
Title: Expression of EGF, EGF-receptor, p53, v-erb B and ras p21 in colorectal neoplasms by immunostaining paraffin-embedded tissues.
Author: Hayashi, Y|Widjono, Y W|Ohta, K|Hanioka, K|Obayashi, C|Itoh, K|Imai, Y|Itoh, H
PMID: 7912978
Journal: Acta Oncol. 1994;33(6):693-701.
Title: Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice.
Author: Radulovic, S|Schally, A V|Reile, H|Halmos, G|Szepeshazi, K|Groot, K|Milovanovic, S|Miller, G|Yano, T
PMID: 7946450
Journal: J Biol Chem. 1994 Jun 24;269(25):17320-8.
Title: Identification and biological characterization of an epidermal growth factor-related protein: cripto-1.
Author: Brandt, R|Normanno, N|Gullick, W J|Lin, J H|Harkins, R|Schneider, D|Jones, B W|Ciardiello, F|Persico, M G|Armenante, F
PMID: 8006041
Journal: J Biol Chem. 1994 May 6;269(18):13231-7.
Title: Two different signal transduction pathways can be activated by transforming growth factor beta 1 in epithelial cells.
Author: Yan, Z|Winawer, S|Friedman, E
PMID: 8175753
Journal: J Med Chem. 1994 May 27;37(11):1689-95.
Title: Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin.
Author: Stevens, M F|McCall, C J|Lelieveld, P|Alexander, P|Richter, A|Davies, D E
PMID: 8201603
Journal: Int J Cancer. 1995 Sep 15;62(6):661-7.
Title: Epidermal growth factor expression in human colon and colon carcinomas: anti-sense epidermal growth factor receptor RNA down-regulates the proliferation of human colon cancer cells.
Author: Rajagopal, S|Huang, S|Moskal, T L|Lee, B N|el-Naggar, A K|Chakrabarty, S
PMID: 7558411
Journal: J Surg Oncol. 1995 Oct;60(2):112-5.
Title: Collagen promotes perianastomotic tumour growth in an experimental animal model.
Author: Reinbach, D|McGregor, J R|Dahill, S W|Docherty, J G|O'Dwyer, P J
PMID: 7564376
Journal: J Nutr. 1995 Jul;125(7 Suppl):2004S-2008S.
Title: Growth regulation of human colon adenocarcinoma-derived cells by calcium, vitamin D and epidermal growth factor.
Author: Cross, H S|Hulla, W|Tong, W M|Peterlik, M
PMID: 7602383
Journal: Gan To Kagaku Ryoho. 1995 Jun;22 Suppl 2:186-91.
Title: [Analysis of malignant potential on colorectal carcinoma utilizing expression of epidermal growth factor and DNA ploidy patterns].
Author: Yamada, H|Kurooka, K|Funai, S|Fujii, Y|Imanishi, Y|Sato, S|Watatani, M|Shindo, K|Yasutomi, M
PMID: 7611788
Journal: Ann Surg Oncol. 1995 May;2(3):257-65.
Title: Characterization and growth factor stimulation of L-arginine transport in a human colon cancer cell line.
Author: Cendan, J C|Souba, W W|Copeland, E M 3rd|Lind, D S
PMID: 7641023
Journal: Ann R Coll Surg Engl. 1995 Mar;77(2):85-9.
Title: Luminal and humoral influences on human rectal epithelial cytokinetics.
Author: Thomas, M G
PMID: 7793821
Journal: Cell Signal. 1995 Nov;7(8):793-801.
Title: Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29).
Author: Balogh, A|Csuka, O|Teplan, I|Keri, G
PMID: 8593248
Journal: Anticancer Res. 1995 Nov-Dec;15(6B):2889-94.
Title: Expression of growth factors and their receptors in human early colorectal carcinomas: immunohistochemical study.
Author: Shirai, H|Ueno, E|Osaki, M|Tatebe, S|Ito, H|Kaibara, N
PMID: 8669884
Journal: J Biol Chem. 1996 Apr 26;271(17):9919-27.
Title: Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange.
Author: Khurana, S|Nath, S K|Levine, S A|Bowser, J M|Tse, C M|Cohen, M E|Donowitz, M
PMID: 8626628
Journal: Oncol Res. 1996;8(7-8):273-9.
Title: Transferrin and insulin enhance human colon tumor cell growth by differentiation class specific mechanisms.
Author: Yeoman, L C|Wan, C W|Zorbas, M A
PMID: 8938790
Journal: Hepatogastroenterology. 1997 Mar-Apr;44(14):435-40.
Title: Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer.
Author: Malecka-Panas, E|Kordek, R|Biernat, W|Tureaud, J|Liberski, P P|Majumdar, A P
PMID: 9164515
Journal: Exp Cell Res. 1997 Aug 1;234(2):465-76.
Title: Differential effects of EGF and amphiregulin on adhesion molecule expression and migration of colon carcinoma cells.
Author: Solic, N|Davies, D E
PMID: 9260917
Journal: Gastroenterology. 1997 Sep;113(3):767-72.
Title: Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients.
Author: Cascinu, S|Del Ferro, E|Grianti, C|Ligi, M|Ghiselli, R|Foglietti, G|Saba, V|Lungarotti, F|Catalano, G
PMID: 9287967
Journal: J Natl Cancer Inst. 1997 Oct 15;89(20):1505-15.
Title: Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns.
Author: Wosikowski, K|Schuurhuis, D|Johnson, K|Paull, K D|Myers, T G|Weinstein, J N|Bates, S E
PMID: 9337347
Journal: J Cell Physiol. 1998 May;175(2):174-83.
Title: Expression of TGFalpha autocrine activity in human colon carcinoma CBS cells is autoregulated and independent of exogenous epidermal growth factor.
Author: Jiang, D|Liang, J|Humphrey, L E|Yang, H|Brattain, M G
PMID: 9525476
Journal: Surgery. 1998 Aug;124(2):248-53.
Title: Butyrate inhibits colon carcinoma cell growth through two distinct pathways.
Author: Archer, S|Meng, S|Wu, J|Johnson, J|Tang, R|Hodin, R
PMID: 9706145
Journal: Z Gastroenterol. 1998 Nov;36(11):947-54.
Title: S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF.
Author: Milovic, V|Turhanowa, L|Fares, F A|Lerner, A|Caspary, W F|Stein, J
PMID: 9880821
Journal: J Surg Res. 1999 Jun 15;84(2):186-92.
Title: Nonsteroidal anti-inflammatory drugs attenuate epidermal growth factor-induced proliferation independent of prostaglandin synthesis inhibition.
Author: Kokoska, E R|Smith, G S|Wolff, A B|Deshpande, Y|Miller, T A
PMID: 10357918
Journal: Nutr Cancer. 1999;34(1):88-99.
Title: Quercetin-induced apoptosis in colorectal tumor cells: possible role of EGF receptor signaling.
Author: Richter, M|Ebermann, R|Marian, B
PMID: 10453447
Journal: Oncol Res. 1999;11(2):77-84.
Title: Mechanism of antimitogenic action of vitamin D in human colon carcinoma cells: relevance for suppression of epidermal growth factor-stimulated cell growth.
Author: Tong, W M|Hofer, H|Ellinger, A|Peterlik, M|Cross, H S
PMID: 10489163
Journal: Oncogene. 1999 Oct 21;18(43):5923-35.
Title: The EGF/TGFalpha response element within the TGFalpha promoter consists of a multi-complex regulatory element.
Author: Awwad, R|Humphrey, L E|Periyasamy, B|Scovell, W Jr|Li, W|Coleman, K|Lynch, M|Carboni, J|Brattain, M G|Howell, G M
PMID: 10557079
Journal: J Gastrointest Surg. 2000 Mar-Apr;4(2):150-61.
Title: Nonsteroidal anti-inflammatory drugs attenuate proliferation of colonic carcinoma cells by blocking epidermal growth factor-induced Ca++ mobilization.
Author: Kokoska, E R|Smith, G S|Miller, T A
PMID: 10675238
Journal: Growth Factors. 2000;18(1):31-49.
Title: Multiple autocrine factors including an extracellular matrix protein are required for the proliferation and spreading of human colon carcinoma cells in vitro.
Author: Pouliot, N|Burgess, A W
PMID: 10831071
Journal: Digestion. 2000;61(4):230-6.
Title: EGF-stimulated polyamine accumulation in the colon carcinoma cell line, Caco-2.
Author: Bauske, R|Milovic, V|Turchanowa, L|Stein, J
PMID: 10878449
Journal: Ann N Y Acad Sci. 2000;915:30-42.
Title: Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts.
Author: Donowitz, M|Janecki, A|Akhter, S|Cavet, M E|Sanchez, F|Lamprecht, G|Zizak, M|Kwon, W L|Khurana, S|Yun, C H|Tse, C M
PMID: 11193592
Journal: J Lab Clin Med. 2001 Sep;138(3):186-92.
Title: Epidermal growth factor induces expression of decay-accelerating factor in human colonic cancer cells via the mitogen-activated protein kinase pathway.
Author: Takeuchi, K|Mizuno, M|Uesu, T|Nasu, J|Kawada, M|Hori, S|Okada, H|Endo, Y|Fujita, T|Tsuji, T
PMID: 11528371
Journal: Nutr Cancer. 2001;41(1-2):172-9.
Title: Neurotensin-and EGF-induced metabolic activation of colon carcinoma cells is diminished by dietary flavonoid cyanidin but not by its glycosides.
Author: Briviba, K|Abrahamse, S L|Pool-Zobel, B L|Rechkemmer, G
PMID: 12094622
Journal: Anal Biochem. 2002 Feb 1;301(1):75-81.
Title: Europium-labeled epidermal growth factor and neurotensin: novel probes for receptor-binding studies.
Author: Mazor, Ohad|Hillairet de Boisferon, Marc|Lombet, Alain|Gruaz-Guyon, Anne|Gayer, Batya|Skrzydelsky, Delphine|Kohen, Fortune|Forgez, Patricia|Scherz, Avigdor|Rostene, William|Salomon, Yoram
PMID: 11811969
Journal: Am J Pathol. 2002 Feb;160(2):389-401.
Title: Beta-catenin--a linchpin in colorectal carcinogenesis?
Author: Wong, Newton Alexander Chiang Shuek|Pignatelli, Massimo
PMID: 11839557
Journal: Exp Cell Res. 2002 Jun 10;276(2):320-7.
Title: Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3).
Author: Bareis, Petra|Kallay, Eniko|Bischof, Martin G|Bises, Giovanna|Hofer, Harald|Potzi, Christian|Manhardt, Teresa|Bland, Rosemary|Cross, Heide S
PMID: 12027461
Journal: J Nutr. 2002 Sep;132(9):2814-8.
Title: Red wine polyphenols inhibit the growth of colon carcinoma cells and modulate the activation pattern of mitogen-activated protein kinases.
Author: Briviba, Karlis|Pan, Lydia|Rechkemmer, Gerhard
PMID: 12221251
Journal: Cancer Res. 2003 Feb 1;63(3):616-20.
Title: Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells.
Author: Rice, Pamela L|Washington, Michele|Schleman, Shea|Beard, K Scott|Driggers, Linda J|Ahnen, Dennis J
PMID: 12566304
Journal: Clin Sci (Lond). 2003 Sep;105(3):323-30.
Title: Effect of epidermal growth factor administration on intestinal cell proliferation, crypt fission and polyp formation in multiple intestinal neoplasia (Min) mice.
Author: Bashir, O|Fitzgerald, A J|Berlanga-Acosta, J|Playford, R J|Goodlad, R A
PMID: 12749762
Journal: J Cell Physiol. 2003 Sep;196(3):454-63.
Title: Gastrin and EGF synergistically induce cyclooxygenase-2 expression in Swiss 3T3 fibroblasts that express the CCK2 receptor.
Author: Slice, Lee W|Hodikian, Raffi|Zhukova, Elena
PMID: 12891702
Journal: Oncology. 2004;66(1):1-17.
Title: The role of new agents in the treatment of colorectal cancer.
Author: Folprecht, Gunnar|Kohne, Claus-Henning
PMID: 15031593
Journal: Cancer Res. 2004 Apr 1;64(7):2601-9.
Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
Author: Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G
PMID: 15059917
Journal: Clin Cancer Res. 2004 Apr 15;10(8):2694-704.
Title: Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer.
Author: Cianchi, Fabio|Cortesini, Camillo|Fantappie, Ornella|Messerini, Luca|Sardi, Iacopo|Lasagna, Nadia|Perna, Federico|Fabbroni, Valentina|Di Felice, Annamaria|Perigli, Giuliano|Mazzanti, Roberto|Masini, Emanuela
PMID: 15102673
Journal: Int J Oncol. 2004 Jun;24(6):1565-72.
Title: Epidermal growth factor upregulates matrix metalloproteinase-7 expression through activation of PEA3 transcription factors.
Author: Lynch, Conor C|Crawford, Howard C|Matrisian, Lynn M|McDonnell, Susan
PMID: 15138601
Journal: Am J Pathol. 2004 Jun;164(6):2139-51.
Title: Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis.
Author: Parikh, Alexander A|Fan, Fan|Liu, Wen Biao|Ahmad, Syed A|Stoeltzing, Oliver|Reinmuth, Niels|Bielenberg, Diane|Bucana, Corazon D|Klagsbrun, Michael|Ellis, Lee M
PMID: 15161648
Journal: Clin Cancer Res. 2004 Dec 15;10(24):8243-9.
Title: Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells.
Author: Mimori, Koshi|Yamashita, Keishi|Ohta, Mitsuhiko|Yoshinaga, Keiji|Ishikawa, Kenji|Ishii, Hideshi|Utsunomiya, Tohru|Barnard, Graham F|Inoue, Hiroshi|Mori, Masaki
PMID: 15623600
Journal:
Title: Epidermal growth factor conjugated to near-infrared fluorescent quantum dots
Author: Chopra, Arvind
PMID: 20641330
Journal: Cancer Res. 2005 May 1;65(9):3716-25.
Title: Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
Author: Yokoi, Kenji|Thaker, Premal H|Yazici, Sertac|Rebhun, Robert R|Nam, Do-Hyun|He, Junqin|Kim, Sun-Jin|Abbruzzese, James L|Hamilton, Stanley R|Fidler, Isaiah J
PMID: 15867367
Journal: Int J Oncol. 2005 Sep;27(3):687-91.
Title: Comparison between triple therapy with octreotide, galanin and serotonin vs. irinotecan or oxaliplatin in combination with 5-fluorouracil/leukovorin in human colon cancer.
Author: El-Salhy, M|Hilding, L|Royson, H|Tjomsland, V
PMID: 16077917
Journal: J Carcinog. 2005 Sep 2;4:16.
Title: Sulindac metabolites inhibit epidermal growth factor receptor activation and expression.
Author: Pangburn, Heather A|Kraus, Hanna|Ahnen, Dennis J|Rice, Pamela L
PMID: 16138927
Journal: Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S89-97.
Title: Enhancing oxaliplatin-based regimens in colorectal cancer by inhibiting the epidermal growth factor receptor pathway.
Author: Kim, George P|Grothey, Axel
PMID: 16336754
Journal: Ann Surg Oncol. 2006 Mar;13(3):353-62.
Title: Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastases.
Author: Yoon, Sam S|Kim, Sung H|Gonen, Mithat|Heffernan, Nancy M|Detwiller, Kara Y|Jarnagin, William R|D'Angelica, Michael|Blumgart, Leslie H|Tanabe, Kenneth K|Dematteo, Ronald P
PMID: 16474912
Journal: Oncology. 2006;70(3):161-7. Epub 2006 May 3.
Title: Targeting the epidermal growth factor receptor in colorectal cancer: advances and controversies.
Author: Italiano, Antoine
PMID: 16675911
Journal: Pharmacogenet Genomics. 2006 Jul;16(7):475-83.
Title: Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.
Author: Zhang, Wu|Gordon, Michael|Press, Oliver A|Rhodes, Katrin|Vallbohmer, Daniel|Yang, Dong Yun|Park, David|Fazzone, William|Schultheis, Anne|Sherrod, Andy E|Iqbal, Syma|Groshen, Susan|Lenz, Heinz-Josef
PMID: 16788380
Journal: Cancer Res. 2006 Jul 1;66(13):6649-56.
Title: Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression.
Author: Mann, Jason R|Backlund, Michael G|Buchanan, F Gregory|Daikoku, Taki|Holla, Vijaykumar R|Rosenberg, Daniel W|Dey, Sudhansu K|DuBois, Raymond N
PMID: 16818638
Journal: Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4426s-4431s.
Title: Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway.
Author: Dimitroulakos, Jim|Lorimer, Ian A|Goss, Glenwood
PMID: 16857822
Journal: Z Gastroenterol. 2006 Aug;44(8):673-81.
Title: [Immunotherapy of colorectal cancer--overview and perspectives].
Author: Schimanski, C C|Horner, V|Kanzler, S|Galle, P R|Moehler, M
PMID: 16902899
Journal: Br J Surg. 2007 Jan;94(1):106-12.
Title: Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines.
Author: Grant, K|Knowles, J|Dawas, K|Burnstock, G|Taylor, I|Loizidou, M
PMID: 17078114
Journal: J Clin Invest. 2007 Aug;117(8):2260-7.
Title: Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
Author: Groenestege, Wouter M Tiel|Thebault, Stephanie|van der Wijst, Jenny|van den Berg, Dennis|Janssen, Rob|Tejpar, Sabine|van den Heuvel, Lambertus P|van Cutsem, Eric|Hoenderop, Joost G|Knoers, Nine V|Bindels, Rene J
PMID: 17671655
Journal: Acta Oncol. 2007;46(8):1113-7.
Title: Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer.
Author: Spindler, Karen-Lise G|Nielsen, Jens N|Ornskov, Dorthe|Brandslund, Ivan|Jakobsen, Anders
PMID: 17851837
Journal: Mol Biol Cell. 2007 Dec;18(12):5004-13. Epub 2007 Oct 10.
Title: Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover.
Author: Lee, Pin-Tse|Liao, Pao-Chi|Chang, Wen-Chang|Tseng, Joseph T
PMID: 17928403
Journal: Clin Colorectal Cancer. 2007 Dec;7 Suppl 1:S21-7.
Title: Update on clinical data with regimens inhibiting angiogenesis and epidermal growth factor receptor for patients with newly diagnosed metastatic colorectal cancer.
Author: Cohen, Deirdre J|Hochster, Howard S
PMID: 18361803
Journal: Int J Biol Markers. 2007 S4 - Jan-Mar;22(4):88-93.
Title: The future of anti-EGFR therapy.
Author: D'Andrea, M R|Gasparini, G
PMID: 28207119
Journal: J Clin Oncol. 2008 Mar 20;26(9):1427-34.
Title: Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer.
Author: Graziano, Francesco|Ruzzo, Annamaria|Loupakis, Fotios|Canestrari, Emanuele|Santini, Daniele|Catalano, Vincenzo|Bisonni, Renato|Torresi, Umberto|Floriani, Irene|Schiavon, Gaia|Andreoni, Francesca|Maltese, Paolo|Rulli, Eliana|Humar, Bostjan|Falcone, Alfredo
PMID: 18349392
Journal: Cornea. 2008 Jun;27(5):612-4.
Title: Persisting corneal erosion under cetuximab (Erbitux) treatment (epidermal growth factor receptor antibody).
Author: Foerster, Claudia G|Cursiefen, Claus|Kruse, Friedrich E
PMID: 18520515
Journal: Carcinogenesis. 2008 Oct;29(10):1986-93.
Title: (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.
Author: Adachi, Seiji|Nagao, Tomokazu|To, Satoshi|Joe, Andrew K|Shimizu, Masahito|Matsushima-Nishiwaki, Rie|Kozawa, Osamu|Moriwaki, Hisataka|Maxfield, Frederick R|Weinstein, I Bernard
PMID: 18586691
Journal: BMC Cancer. 2008 Aug 8;8:227.
Title: Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines.
Author: Solmi, Rossella|Lauriola, Mattia|Francesconi, Mirko|Martini, Desiree|Voltattorni, Manuela|Ceccarelli, Claudio|Ugolini, Giampaolo|Rosati, Giancarlo|Zanotti, Simone|Montroni, Isacco|Mattei, Gabriella|Taffurelli, Mario|Santini, Donatella|Pezzetti, Furio|Rugg
PMID: 18691415
Journal: Clin Cancer Res. 2008 Nov 15;14(22):7413-22.
Title: Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.
Author: Manning, H Charles|Merchant, Nipun B|Foutch, A Coe|Virostko, John M|Wyatt, Shelby K|Shah, Chirayu|McKinley, Eliot T|Xie, Jingping|Mutic, Nathan J|Washington, M Kay|LaFleur, Bonnie|Tantawy, Mohammed Noor|Peterson, Todd E|Ansari, M Sib|Baldwin, Ronald M|Rot
PMID: 19010858
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Jan;12(1):69-72.
Title: [Synergistic use of epidermal growth factor and 5-fluorouracil for the treatment of human colorectal cancer in BALB/C nude mice subcutaneous xenograft model].
Author: Ye, Lin|Wang, Guo-Bin|Tao, Kai-Xiong
PMID: 19145509
Journal: Anticancer Res. 2009 Jan;29(1):229-34.
Title: Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines.
Author: Wu, William Ka Kei|Tse, Timothy Tim Ming|Sung, Joseph Jao Yiu|Li, Zhi Jie|Yu, Le|Cho, Chi Hin
PMID: 19331154
Journal: PLoS Comput Biol. 2009 Apr;5(4):e1000340.
Title: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.
Author: Aldridge, Bree B|Saez-Rodriguez, Julio|Muhlich, Jeremy L|Sorger, Peter K|Lauffenburger, Douglas A
PMID: 19343194
Journal: J Cell Physiol. 2009 Oct;221(1):189-94.
Title: Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.
Author: Cascio, Sandra|Ferla, Rita|D'Andrea, Aleco|Gerbino, Aldo|Bazan, Viviana|Surmacz, Eva|Russo, Antonio
PMID: 19492417
Journal: Int J Cancer. 2009 Nov 1;125(9):2029-35.
Title: Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers.
Author: Ikeuchi, Kyoko|Marusawa, Hiroyuki|Fujiwara, Mikio|Matsumoto, Yuko|Endo, Yoko|Watanabe, Tomohiro|Iwai, Akio|Sakai, Yoshiharu|Takahashi, Ryosuke|Chiba, Tsutomu
PMID: 19585504
Journal: Ai Zheng. 2009 Sep;28(9):950-4.
Title: [Expression and clinical significance of metastasis-related tumor markers in colorectal cancer].
Author: Wan, Xiang-Bin|Pan, Zhi-Zhong|Ren, Ying-kun|Ding, Pei-Rong|Chen, Gong|Wan, De-Sen
PMID: 19728913
Journal: Mol Cancer. 2009 Sep 25;8:77.
Title: Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.
Author: Koslowski, Michael|Tureci, Ozlem|Huber, Christoph|Sahin, Ugur
PMID: 19781065
Journal: Anticancer Res. 2009 Oct;29(10):3957-65.
Title: Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells.
Author: Palomares, Teodoro|Carames, Marta|Garcia-Alonso, Ignacio|Alonso-Varona, Ana
PMID: 19846936
Journal: Wien Klin Wochenschr. 2009;121(19-20):638-43.
Title: The EGF 61A/G polymorphism - a predictive marker for recurrence of liver metastases from colorectal cancer.
Author: Kovar, Florian M|Thallinger, Christiane|Marsik, Claudia L|Perkmann, Thomas|Puhalla, Harald|Haslacher, Helmuth|Wrba, Fritz|Wagner, Oswald F|Gruenberger, Thomas|Endler, Georg
PMID: 19921131
Journal: Exp Clin Endocrinol Diabetes. 2010 Jul;118(7):410-9.
Title: Antiproliferative/cytotoxic activity of molecular iodine and iodolactones in various human carcinoma cell lines. No interfering with EGF-signaling, but evidence for apoptosis.
Author: Rosner, H|Torremante, P|Moller, W|Gartner, R
PMID: 19802778
Journal: Int J Oncol. 2010 Mar;36(3):585-92.
Title: Rho-kinase regulates negatively the epidermal growth factor-stimulated colon cancer cell proliferation.
Author: Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kozawa, Osamu|Moriwaki, Hisataka
PMID: 20126978
Journal: Chem Biol Interact. 2010 May 14;185(3):247-52.
Title: (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
Author: Shimizu, Masahito|Shirakami, Yohei|Sakai, Hiroyasu|Yasuda, Yoichi|Kubota, Masaya|Adachi, Seiji|Tsurumi, Hisashi|Hara, Yukihiko|Moriwaki, Hisataka
PMID: 20346928
Journal: Recent Results Cancer Res. 2010;182:155-66.
Title: Multimodality therapy for adenocarcinoma of the esophagus, gastric cardia, and upper gastric third.
Author: Reynolds, John V|Murphy, Thomas J|Ravi, Narayamasamy
PMID: 20676879
Journal: J Biomed Res. 2010 Jan;24(1):64-8.
Title: Reduction of G0 phase cells of colon cancer caco-2 cells may enhance 5-fluorouracil efficacy.
Author: Ye, Lin|Tao, Kaixiong|Yu, Yang|Wang, Guobin
PMID: 23554613
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G749-60.
Title: Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.
Author: Belo, Angelica|Cheng, Kunrong|Chahdi, Ahmed|Shant, Jasleen|Xie, Guofeng|Khurana, Sandeep|Raufman, Jean-Pierre
PMID: 21273532
Journal: Carcinogenesis. 2011 Jun;32(6):921-8.
Title: Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK.
Author: Kang, Nam Joo|Lee, Ki Won|Kim, Bo Hyun|Bode, Ann M|Lee, Hyo-Jeong|Heo, Yong-Seok|Boardman, Lisa|Limburg, Paul|Lee, Hyong Joo|Dong, Zigang
PMID: 21317303
Journal: Int J Oncol. 2011 May;38(5):1365-73.
Title: Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells.
Author: Vidal, Flavia|de Araujo, Wallace Martins|Cruz, Andre L S|Tanaka, Marcelo Neves|Viola, Joao P B|Morgado-Diaz, Jose A
PMID: 21369697
Journal: HPB (Oxford). 2011 Apr;13(4):246-55.
Title: Changes in growth factor levels after thermal ablation in a murine model of colorectal liver metastases.
Author: Fifis, Theodora|Malcontenti-Wilson, Caterina|Amijoyo, Jason|Anggono, Beatrice|Muralidharan, Vijayaragavan|Nikfarjam, Mehrdad|Christophi, Christopher
PMID: 21418130
Journal: BMC Cancer. 2011 Jun 3;11:219.
Title: Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.
Author: Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Savkovic, Suzana D
PMID: 21639915
Journal: Carcinogenesis. 2011 Aug;32(8):1259-67.
Title: Inhibition of aldose reductase prevents colon cancer metastasis.
Author: Tammali, Ravinder|Reddy, Aramati B M|Saxena, Ashish|Rychahou, Piotr G|Evers, B Mark|Qiu, Suimin|Awasthi, Sanjay|Ramana, Kota V|Srivastava, Satish K
PMID: 21642355
Journal: BMC Cancer. 2011 Oct 2;11:421.
Title: Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.
Author: Muller, Kristin M|Tveteraas, Ingun H|Aasrum, Monica|Odegard, John|Dawood, Mona|Dajani, Olav|Christoffersen, Thoralf|Sandnes, Dagny L
PMID: 21961726
Journal: BMC Cancer. 2011 Nov 25;11:496.
Title: Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.
Author: Dahan, Laetitia|Norguet, Emmanuelle|Etienne-Grimaldi, Marie-Christine|Formento, Jean-Louis|Gasmi, Mohamed|Nanni, Isabelle|Gaudart, Jean|Garcia, Stephane|Ouafik, L'Houcine|Seitz, Jean-Francois|Milano, Gerard
PMID: 22117530
Journal: Pol Przegl Chir. 2011 Jan;83(1):42-7.
Title: Evaluation of endostatin and EGF serum levels in patients with gastric cancer.
Author: Masiak, Wioletta|Szponar, Anna|Chodorowska, Grazyna|Dabrowski, Andrzej|Pedowski, Tomasz|Wallner, Grzegorz
PMID: 22166241
Journal: Cancers (Basel). 2011 Oct 14;3(4):3894-908.
Title: The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer.
Author: Wang, Dingzhi|Xia, Dianren|Dubois, Raymond N
PMID: 24213116
Journal: Med Oncol. 2012 Jun;29(2):1044-9.
Title: Effect of rs6983267 polymorphism in the 8q24 region and rs4444903 polymorphism in EGF gene on the risk of sporadic colorectal cancer in Iranian population.
Author: Daraei, A|Salehi, R|Salehi, M|Emami, M H|Janghorbani, M|Mohamadhashem, F|Tavakoli, H
PMID: 21567271
Journal: Mol Carcinog. 2012 Oct;51(10):783-95.
Title: Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells.
Author: Bocca, Claudia|Bozzo, Francesca|Cannito, Stefania|Parola, Maurizio|Miglietta, Antonella
PMID: 21882253
Journal: DNA Cell Biol. 2012 Apr;31(4):568-74.
Title: Meta-analysis of epidermal growth factor polymorphisms and cancer risk: involving 9,779 cases and 15,932 controls.
Author: Li, Teng-Fei|Ren, Ke-Wei|Liu, Peng-Fei
PMID: 22070650
Journal: Biochem Pharmacol. 2012 Apr 1;83(7):849-57.
Title: Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.
Author: Park, Jung-Jin|Yi, Jae Youn|Jin, Yeung Bae|Lee, Yoon-Jin|Lee, Jae-Seon|Lee, Yun-Sil|Ko, Young-Gyu|Lee, Minyoung
PMID: 22266356
Journal: World J Gastroenterol. 2012 Feb 21;18(7):637-45.
Title: Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array.
Author: Abajo, Ana|Bitarte, Nerea|Zarate, Ruth|Boni, Valentina|Lopez, Ines|Gonzalez-Huarriz, Marisol|Rodriguez, Javier|Bandres, Eva|Garcia-Foncillas, Jesus
PMID: 22363134
Journal: Proc Natl Acad Sci U S A. 2012 May 15;109(20):7776-81.
Title: Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition.
Author: Sakuma, Keiichiro|Aoki, Masahiro|Kannagi, Reiji
PMID: 22547830
Journal: Genet Test Mol Biomarkers. 2012 Sep;16(9):1142-5.
Title: Association of epidermal growth factor +61 A/G polymorphism in Chinese patients with colon cancer.
Author: Lin, Lin|Li, Guixin|Zhang, Zhanxue|Wen, Ming|Xu, Weili|Cai, Jianhui|Zhou, Baojun|Liu, Jin
PMID: 22621366
Journal: Anticancer Res. 2012 Jun;32(6):2315-21.
Title: Amphiregulin is a prognostic factor in colorectal cancer.
Author: Ohchi, Takafumi|Akagi, Yoshito|Kinugasa, Tetsushi|Kakuma, Tatsuyuki|Kawahara, Akihiro|Sasatomi, Teruo|Gotanda, Yukito|Yamaguchi, Keizo|Tanaka, Natsuki|Ishibashi, Yoshiaki|Miyamoto, Shingo|Kage, Masayoshi|Shirouzu, Kazuo
PMID: 22641668
Journal: J Biol Chem. 2012 Jul 27;287(31):25881-92.
Title: Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway.
Author: Peng, Cong|Zhu, Feng|Wen, Weihong|Yao, Ke|Li, Shengqing|Zykova, Tatyana|Liu, Kangdong|Li, Xiang|Ma, Wei-Ya|Bode, Ann M|Dong, Zigang
PMID: 22685297
Journal: J Biol Chem. 2012 Nov 23;287(48):40371-80.
Title: Epidermal growth factor (EGF) regulates alpha5beta1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A.
Author: Vial, Daniel|McKeown-Longo, Paula J
PMID: 23007402
Journal: Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21046-51.
Title: Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
Author: Ashraf, Shazad Q|Nicholls, Angela M|Wilding, Jennifer L|Ntouroupi, Triantafyllia G|Mortensen, Neil J|Bodmer, Walter F
PMID: 23213241
Journal: Invest New Drugs. 2013 Jun;31(3):516-24.
Title: Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Author: Gialeli, Ch|Theocharis, A D|Kletsas, D|Tzanakakis, G N|Karamanos, N K
PMID: 22956286
Journal: Gene. 2013 Apr 25;519(1):26-33.
Title: EGF +61A>G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis.
Author: Piao, Ying|Liu, Zhaozhe|Ding, Zhenyu|Xu, Long|Guo, Fang|Sun, Qingqing|Xie, Xiaodong
PMID: 23403233
Journal: Oncol Lett. 2013 Feb;5(2):521-526.
Title: Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cells.
Author: Pan, Tao|Sun, Junfeng|Zhou, Jun|Fu, Zhixuan|Hu, Yiwang|Zheng, Shu|Zhang, Suzhan
PMID: 23420529
Journal: BMC Cancer. 2013 May 2;13:221.
Title: Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors.
Author: Ludwig, Kirsten|Tse, Edison S|Wang, Jean Yj
PMID: 23638973
Journal: PLoS One. 2013 Sep 19;8(9):e74994.
Title: Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling.
Author: de Souza, Waldemir F|Fortunato-Miranda, Natalia|Robbs, Bruno K|de Araujo, Wallace M|de-Freitas-Junior, Julio C|Bastos, Lilian G|Viola, Joao P B|Morgado-Diaz, Jose A
PMID: 24069372
Journal: Oncol Lett. 2013 Oct;6(4):1079-1083.
Title: Correlation between the EGF gene intronic polymorphism, rs2298979, and colorectal cancer.
Author: Chaleshi, Vahid|Haghighi, Mahdi Montazer|Savabkar, Sanaz|Zali, Neda|Vahedi, Mohsen|Khanyaghma, Mahsa|Javadi, Gholam Reza|Asadzade, Hamid|Zali, Mohammad Reza
PMID: 24137467
Journal: BMC Cancer. 2013 Nov 2;13:518.
Title: Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.
Author: Khong, Tak L|Thairu, Ngayu|Larsen, Helene|Dawson, Peter M|Kiriakidis, Serafim|Paleolog, Ewa M
PMID: 24180698
Journal: Gastroenterol Hepatol Bed Bench. 2013 Summer;6(3):129-35.
Title: The effect of 5'untranslated region polymorphism in EGF gene, rs4444903, on colorectal cancer.
Author: Chaleshi, Vahid|Haghighi, Mahdi Montazer|Javadi, Gholam Reza|Fatemi, Seyed Reza|Vahedi, Mohsen|Zali, Mohammad Reza
PMID: 24834259
Journal: Gastroenterol Hepatol Bed Bench. 2013;6(Suppl 1):S32-8.
Title: Different frequency of epidermal growth factor rs76189946 polymorphism genotype in an Iranian colorectal cancer.
Author: Chaleshi, Vahid|Savabkar, Sanaz|Dolatmoradi, Hesamodin|Haghighi, Mahdi Montazer|Maryan, Elmira Khalili|Pasha, Sara|Vandfaez, Narges Ebrahimi|Nazemalhosseini Mojarad, Ehsan|Aghdaei, Hamid Asadzadeh|Zali, Mohammad Reza
PMID: 24834285
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E72-84.
Title: The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.
Author: Weng, Yu-Rong|Kong, Xuan|Yu, Ya-Nan|Wang, Ying-Chao|Hong, Jie|Zhao, Shu-Liang|Fang, Jing-Yuan
PMID: 23625650
Journal: Oncogene. 2014 Apr 17;33(16):2123-33.
Title: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author: Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J
PMID: 23644655
Journal: Anticancer Res. 2014 Apr;34(4):1793-800.
Title: COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-alpha.
Author: Bocca, Claudia|Bozzo, Francesca|Miglietta, Antonella
PMID: 24692712
Journal: Biochim Biophys Acta. 2014 Aug;1840(8):2651-61.
Title: EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.
Author: Ellina, Maria-Ioanna|Bouris, Panagiotis|Aletras, Alexios J|Theocharis, Achilleas D|Kletsas, Dimitris|Karamanos, Nikos K
PMID: 24792576
Journal: Oncol Rep. 2014 Aug;32(2):821-8.
Title: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author: Kundu, Juthika|Choi, Bu Young|Jeong, Chul-Ho|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24890449
Journal: Clin Cancer Res. 2014 Aug 1;20(15):4115-28.
Title: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells.
Author: Bae, Jeong A|Yoon, Somy|Park, So-Yeon|Lee, Jae Hyuk|Hwang, Jun-Eul|Kim, Hangun|Seo, Young-Woo|Cha, Yoon Jin|Hong, Sung Pil|Kim, Hoguen|Chung, Ik Joo|Kim, Kyung Keun
PMID: 24893630
Journal: Asian Pac J Trop Med. 2014 May;7(5):378-81.
Title: Effect of Yiqi Jianpi plus anticancer herbs on spleen deficiency in colorectal cancer and its anti-tumor role.
Author: Fu, Li-Ran|Guo, Sheng-Wei|Liu, Xian-Hui
PMID: 25063064
Journal: Genet Mol Res. 2014 Jul 25;13(3):5555-61.
Title: Association between EGF and VEGF functional polymorphisms and sporadic colorectal cancer in the Malaysian population.
Author: Lau, T P|Roslani, A C|Lian, L H|Lee, P C|Hilmi, I|Goh, K L|Chua, K H
PMID: 25117311
Journal: PLoS One. 2014 Aug 14;9(8):e104891.
Title: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Author: Lien, Gi-Shih|Wu, Ming-Shun|Bien, Mauo-Ying|Chen, Chien-Hsin|Lin, Chien-Huang|Chen, Bing-Chang
PMID: 25122478
Journal: Oncol Rep. 2014 Dec;32(6):2359-64.
Title: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow.
Author: Tawada, Masahiro|Hayashi, Shin-Ichiro|Ikegame, Yuka|Nakashima, Shigeru|Yoshida, Kazuhiro
PMID: 25242215
Journal: Mol Cancer Res. 2015 Jul;13(7):1130-8.
Title: SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
Author: Ida, Satoshi|Ozaki, Nobuyuki|Araki, Kimi|Hirashima, Kotaro|Zaitsu, Yoko|Taki, Katsunobu|Sakamoto, Yasuo|Miyamoto, Yuji|Oki, Eiji|Morita, Masaru|Watanabe, Masayuki|Maehara, Yoshihiko|Yamamura, Ken-Ichi|Baba, Hideo|Ohmuraya, Masaki
PMID: 25804623
Journal: Nature. 2015 May 7;521(7550):43-7.
Title: Sequential cancer mutations in cultured human intestinal stem cells.
Author: Drost, Jarno|van Jaarsveld, Richard H|Ponsioen, Bas|Zimberlin, Cheryl|van Boxtel, Ruben|Buijs, Arjan|Sachs, Norman|Overmeer, Rene M|Offerhaus, G Johan|Begthel, Harry|Korving, Jeroen|van de Wetering, Marc|Schwank, Gerald|Logtenberg, Meike|Cuppen, Edwin|Sni
PMID: 25924068
Journal: Oncogene. 2016 Jun 16;35(24):3190-200.
Title: The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
Author: Rey, C|Faustin, B|Mahouche, I|Ruggieri, R|Brulard, C|Ichas, F|Soubeyran, I|Lartigue, L|De Giorgi, F
PMID: 26522728
Journal: J Biol Chem. 2016 Jan 29;291(5):2319-30.
Title: Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.
Author: Kado, Yuji|Mizohata, Eiichi|Nagatoishi, Satoru|Iijima, Mariko|Shinoda, Keiko|Miyafusa, Takamitsu|Nakayama, Taisuke|Yoshizumi, Takuma|Sugiyama, Akira|Kawamura, Takeshi|Lee, Young-Hun|Matsumura, Hiroyoshi|Doi, Hirofumi|Fujitani, Hideaki|Kodama, Tatsuhiko|Sh
PMID: 26627827
Journal: Cancer Res. 2016 Feb 15;76(4):855-65.
Title: NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells.
Author: Joo, Jung Hee|Oh, Hyunjin|Kim, Myungjin|An, Eun Jung|Kim, Rae-Kwon|Lee, So-Young|Kang, Dong Hoon|Kang, Sang Won|Keun Park, Cheol|Kim, Hoguen|Lee, Su-Jae|Lee, Daekee|Seol, Jae Hong|Bae, Yun Soo
PMID: 26781991
Journal: BMB Rep. 2016 Apr;49(4):220-5.
Title: Biphasic activation of extracellular signal-regulated kinase (ERK) 1/2 in epidermal growth factor (EGF)-stimulated SW480 colorectal cancer cells.
Author: Joo, Donghyun|Woo, Jong Soo|Cho, Kwang-Hyun|Han, Seung Hyun|Min, Tae Sun|Yang, Deok-Chun|Yun, Cheol-Heui
PMID: 26879318
Journal: Anticancer Res. 2016 Apr;36(4):1901-7.
Title: Predictive Value of Growth Factors and Interleukins for Future Liver Remnant Volume and Colorectal Liver Metastasis Volume Growth Following Portal Vein Embolization and Autologous Stem Cell Application.
Author: Fichtl, Jakub|Treska, Vladislav|Lysak, Daniel|Mirka, Hynek|Duras, Petr|Karlikova, Marie|Skalicky, Tomas|Vodicka, Josef|Topolcan, Ondrej
PMID: 27069178
Journal: Biochem Biophys Res Commun. 2016 Sep 2;477(4):801-806.
Title: Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation.
Author: Tashiro, Etsu|Henmi, Shizuka|Odake, Hiroyuki|Ino, Seitaro|Imoto, Masaya
PMID: 27369075
Journal: Cancer Med. 2016 Sep;5(9):2249-60.
Title: Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
Author: Hatch, Ace J|Sibley, Alexander B|Starr, Mark D|Brady, J Chris|Jiang, Chen|Jia, Jingquan|Bowers, Daniel L|Pang, Herbert|Owzar, Kouros|Niedzwiecki, Donna|Innocenti, Federico|Venook, Alan P|Hurwitz, Herbert I|Nixon, Andrew B
PMID: 27465221
Journal: J Clin Invest. 2016 Nov 1;126(11):4157-4173.
Title: Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer.
Author: Yin, Mingzhu|Li, Xia|Tan, Shu|Zhou, Huanjiao Jenny|Ji, Weidong|Bellone, Stefania|Xu, Xiaocao|Zhang, Haifeng|Santin, Alessandro D|Lou, Ge|Min, Wang
PMID: 27721235
Journal: Eur J Pharmacol. 2017 Feb 15;797:1-8.
Title: SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer.
Author: Zhang, Li-Li|Zhan, Lin|Jin, Yong-Dong|Min, Zhen-Li|Wei, Can|Wang, Qiang|Chen, Ya-Jun|Wu, Qing-Ming|Hu, Xia-Min|Yuan, Qiong
PMID: 28088387
Journal: Biomed Pharmacother. 2017 Aug;92:140-148.
Title: Ezrin/NF-kB activation regulates epithelial- mesenchymal transition induced by EGF and promotes metastasis of colorectal cancer.
Author: Li, Yingru|Lin, Zhaoyu|Chen, Bin|Chen, Shuang|Jiang, Zhipeng|Zhou, Taicheng|Hou, Zehui|Wang, Youyuan
PMID: 28535417
Journal: Cancer Lett. 2017 Oct 28;407:93-105.
Title: Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.
Author: Oberthur, Rabea|Seemann, Henning|Gehrig, Julia|Rave-Frank, Margret|Bremmer, Felix|Halpape, Rovena|Conradi, Lena-Christin|Scharf, Jens-Gerd|Burfeind, Peter|Kaulfuss, Silke
PMID: 28823963
Journal: Stem Cells. 2018 Feb;36(2):252-264.
Title: Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.
Author: Piryani, Sadhna O|Kam, Angel Y F|Kliassov, Evelyna G|Chen, Benny J|Spector, Neil L|Chute, John P|Hsu, David S|Chao, Nelson J|Doan, Phuong L
PMID: 29086459
Journal: Br J Cancer. 2018 Feb 20;118(4):558-565.
Title: LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.
Author: Morgan, R G|Mortensson, E|Legge, D N|Gupta, B|Collard, T J|Greenhough, A|Williams, A C
PMID: 29149105
Journal: Cancer Res Treat. 2018 Jan 17. pii: crt.2017.487.
Title: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.
Author: Yun, Sumi|Kwak, Yoonjin|Nam, Soo Kyung|Seo, An Na|Oh, Heung-Kwon|Kim, Duck-Woo|Kang, Sung-Bum|Lee, Hye Seung
PMID: 29361822
Journal: Cancer Lett. 2018 Apr 10;419:245-256.
Title: Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation.
Author: Ren, X L|Qiao, Y D|Li, J Y|Li, X M|Zhang, D|Zhang, X J|Zhu, X H|Zhou, W J|Shi, J|Wang, W|Liao, W T|Ding, Y Q|Liang, L
PMID: 29374558
Journal: Cancer Cell Int. 2018 Mar 5;18:32.
Title: Epidermal growth factor-mediated Rab25 pathway regulates integrin beta1 trafficking in colon cancer.
Author: Hong, Kyung Sook|Jeon, Eun-Young|Chung, Soon Sup|Kim, Kwang Ho|Lee, Ryung-Ah
PMID: 29515334
Journal: Oncotarget. 2018 Apr 24;9(31):21950-21964.
Title: An improved method for culturing patient-derived colorectal cancer spheroids.
Author: Miyoshi, Hiroyuki|Maekawa, Hisatsugu|Kakizaki, Fumihiko|Yamaura, Tadayoshi|Kawada, Kenji|Sakai, Yoshiharu|Taketo, M Mark
PMID: 29774115
Journal: J Biomed Sci. 2018 Aug 2;25(1):60.
Title: STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening.
Author: Cheng, Chun-Chia|Liao, Po-Nien|Ho, Ai-Sheng|Lim, Ken-Hong|Chang, Jungshan|Su, Ying-Wen|Chen, Caleb Gon-Shen|Chiang, Ya-Wen|Yang, Bi-Ling|Lin, Huan-Chau|Chang, Yu-Cheng|Chang, Chun-Chao|Chang, Yi-Fang
PMID: 30068339
Journal: Oncol Rep. 2018 Nov;40(5):2690-2697.
Title: EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFRpositive cancer cells.
Author: Hashimi, Saeed M|Grant, Brock|Alqurashi, Naif|Alowaidi, Faisal|Wei, Ming Q
PMID: 30226622
Journal: Cancers (Basel). 2018 Oct 22;10(10). pii: cancers10100393.
Title: Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer.
Author: Chu, Chun-Ho|Chang, Shih-Ching|Wang, Hsiu-Hua|Yang, Shung-Haur|Lai, Kuo-Chu|Lee, Te-Chang
PMID: 30360391