Primary Site >> Colorectal Cancer
Gene >> EGF
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Ref: Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice. PMID: 3873715 |
Ref: Increased expression of the epidermal growth factor receptor on human colon carcinoma cells. PMID: 3535739 |
Ref: Adenylate cyclase activity and cyclic adenosine monophosphate levels in colon cancer lines and dermal fibroblasts and the effects of cholera toxin and epidermal growth factor. PMID: 2837611 Ref: Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose. PMID: 3281751 |
Ref: Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line. PMID: 2539250 Ref: Examination of the effects of epidermal growth factor on the production of urokinase and the expression of the plasminogen activator receptor in a human colon cancer cell line. PMID: 2539903 Ref: Epidermal growth factor receptors and epidermal growth factor-like activity in colorectal mucosa, adenomas and carcinomas. PMID: 2544769 Ref: Expression of TGF-alpha/EGF and TGF-beta receptors in human colon carcinoma cell lines. PMID: 2545633 Ref: Binding of epidermal growth factor by human colon carcinoma cell (Caco-2) monolayers. PMID: 2785387 Ref: Examination of urokinase protein/transcript levels and their relationship with laminin degradation in cultured colon carcinoma. PMID: 2912554 |
Ref: Epithelial tumor cells in bone marrow of patients with colorectal cancer: immunocytochemical detection, phenotypic characterization, and prognostic significance. PMID: 1692090 Ref: Expression of several growth factors and their receptor genes in human colon carcinomas. PMID: 1980764 Ref: Growth factors and oncogenes in human gastrointestinal carcinomas. PMID: 2157713 Ref: Biotinylated epidermal growth factor: a useful tool for the histochemical analysis of specific binding sites. PMID: 2228731 Ref: Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha. PMID: 2250044 Ref: [Immunohistochemical studies on the expression of epidermal growth factor (EGF) in human colorectal cancers]. PMID: 2384983 |
Ref: Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors. PMID: 1672042 Ref: Effects of epidermal growth factor on diamine oxidase expression and cell growth in Caco-2 cells. PMID: 1681737 Ref: Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient. PMID: 1847663 |
Ref: Identification of basic fibroblast growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines. PMID: 1310324 Ref: Effects of partial hepatectomy on the growth characteristics and hypoxic fractions of xenografted DLD-2 human colon cancers. PMID: 1438710 Ref: Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line. PMID: 1457828 Ref: Proliferation of human colon cancer cells: role of epidermal growth factor and transforming growth factor alpha. PMID: 1459740 Ref: Immunoreactive transforming growth factor-alpha and epidermal growth factor in colorectal adenomas and carcinomas. PMID: 1528573 Ref: Sex steroid hormone receptors, epidermal growth factor receptor, and polyamines in human colorectal cancer. PMID: 1582349 |
Ref: Epidermal growth factor increases 32P incorporation into phosphatidylcholine and protein kinase C activity in colon carcinoma cell line (HT29). PMID: 8130082 Ref: Epidermal growth factor induces serine phosphorylation of stathmin in a human colon carcinoma cell line (LIM 1215). PMID: 8514777 |
Ref: 5-Aza-2'-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells. PMID: 7514437 Ref: Urinary epidermal growth factor receptor-binding growth factors in patients with cancers of the digestive tract. PMID: 7697894 Ref: Caco-2 cells express type I interleukin-1 receptors: ligand binding enhances proliferation. PMID: 7810657 Ref: Divergent effects of epidermal growth factor and calcipotriol on human rectal cell proliferation. PMID: 7829012 Ref: Expression of EGF, EGF-receptor, p53, v-erb B and ras p21 in colorectal neoplasms by immunostaining paraffin-embedded tissues. PMID: 7912978 Ref: Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice. PMID: 7946450 Ref: Identification and biological characterization of an epidermal growth factor-related protein: cripto-1. PMID: 8006041 Ref: Two different signal transduction pathways can be activated by transforming growth factor beta 1 in epithelial cells. PMID: 8175753 Ref: Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin. PMID: 8201603 |
Ref: Epidermal growth factor expression in human colon and colon carcinomas: anti-sense epidermal growth factor receptor RNA down-regulates the proliferation of human colon cancer cells. PMID: 7558411 Ref: Collagen promotes perianastomotic tumour growth in an experimental animal model. PMID: 7564376 Ref: Growth regulation of human colon adenocarcinoma-derived cells by calcium, vitamin D and epidermal growth factor. PMID: 7602383 Ref: [Analysis of malignant potential on colorectal carcinoma utilizing expression of epidermal growth factor and DNA ploidy patterns]. PMID: 7611788 Ref: Characterization and growth factor stimulation of L-arginine transport in a human colon cancer cell line. PMID: 7641023 Ref: Luminal and humoral influences on human rectal epithelial cytokinetics. PMID: 7793821 Ref: Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29). PMID: 8593248 Ref: Expression of growth factors and their receptors in human early colorectal carcinomas: immunohistochemical study. PMID: 8669884 |
Ref: Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange. PMID: 8626628 Ref: Transferrin and insulin enhance human colon tumor cell growth by differentiation class specific mechanisms. PMID: 8938790 |
Ref: Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer. PMID: 9164515 Ref: Differential effects of EGF and amphiregulin on adhesion molecule expression and migration of colon carcinoma cells. PMID: 9260917 Ref: Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients. PMID: 9287967 Ref: Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns. PMID: 9337347 |
Ref: Expression of TGFalpha autocrine activity in human colon carcinoma CBS cells is autoregulated and independent of exogenous epidermal growth factor. PMID: 9525476 Ref: Butyrate inhibits colon carcinoma cell growth through two distinct pathways. PMID: 9706145 Ref: S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF. PMID: 9880821 |
Ref: Nonsteroidal anti-inflammatory drugs attenuate epidermal growth factor-induced proliferation independent of prostaglandin synthesis inhibition. PMID: 10357918 Ref: Quercetin-induced apoptosis in colorectal tumor cells: possible role of EGF receptor signaling. PMID: 10453447 Ref: Mechanism of antimitogenic action of vitamin D in human colon carcinoma cells: relevance for suppression of epidermal growth factor-stimulated cell growth. PMID: 10489163 Ref: The EGF/TGFalpha response element within the TGFalpha promoter consists of a multi-complex regulatory element. PMID: 10557079 |
Ref: Nonsteroidal anti-inflammatory drugs attenuate proliferation of colonic carcinoma cells by blocking epidermal growth factor-induced Ca++ mobilization. PMID: 10675238 Ref: Multiple autocrine factors including an extracellular matrix protein are required for the proliferation and spreading of human colon carcinoma cells in vitro. PMID: 10831071 Ref: EGF-stimulated polyamine accumulation in the colon carcinoma cell line, Caco-2. PMID: 10878449 Ref: Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts. PMID: 11193592 |
Ref: Epidermal growth factor induces expression of decay-accelerating factor in human colonic cancer cells via the mitogen-activated protein kinase pathway. PMID: 11528371 Ref: Neurotensin-and EGF-induced metabolic activation of colon carcinoma cells is diminished by dietary flavonoid cyanidin but not by its glycosides. PMID: 12094622 |
Ref: Europium-labeled epidermal growth factor and neurotensin: novel probes for receptor-binding studies. PMID: 11811969 Ref: Beta-catenin--a linchpin in colorectal carcinogenesis? PMID: 11839557 Ref: Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). PMID: 12027461 Ref: Red wine polyphenols inhibit the growth of colon carcinoma cells and modulate the activation pattern of mitogen-activated protein kinases. PMID: 12221251 |
Ref: Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells. PMID: 12566304 Ref: Effect of epidermal growth factor administration on intestinal cell proliferation, crypt fission and polyp formation in multiple intestinal neoplasia (Min) mice. PMID: 12749762 Ref: Gastrin and EGF synergistically induce cyclooxygenase-2 expression in Swiss 3T3 fibroblasts that express the CCK2 receptor. PMID: 12891702 |
Ref: The role of new agents in the treatment of colorectal cancer. PMID: 15031593 Ref: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. PMID: 15059917 Ref: Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer. PMID: 15102673 Ref: Epidermal growth factor upregulates matrix metalloproteinase-7 expression through activation of PEA3 transcription factors. PMID: 15138601 Ref: Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis. PMID: 15161648 Ref: Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells. PMID: 15623600 Ref: Epidermal growth factor conjugated to near-infrared fluorescent quantum dots PMID: 20641330 |
Ref: Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. PMID: 15867367 Ref: Comparison between triple therapy with octreotide, galanin and serotonin vs. irinotecan or oxaliplatin in combination with 5-fluorouracil/leukovorin in human colon cancer. PMID: 16077917 Ref: Sulindac metabolites inhibit epidermal growth factor receptor activation and expression. PMID: 16138927 Ref: Enhancing oxaliplatin-based regimens in colorectal cancer by inhibiting the epidermal growth factor receptor pathway. PMID: 16336754 |
Ref: Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastases. PMID: 16474912 Ref: Targeting the epidermal growth factor receptor in colorectal cancer: advances and controversies. PMID: 16675911 Ref: Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab. PMID: 16788380 Ref: Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. PMID: 16818638 Ref: Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway. PMID: 16857822 Ref: [Immunotherapy of colorectal cancer--overview and perspectives]. PMID: 16902899 |
Ref: Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines. PMID: 17078114 Ref: Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia. PMID: 17671655 Ref: Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer. PMID: 17851837 Ref: Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. PMID: 17928403 Ref: Update on clinical data with regimens inhibiting angiogenesis and epidermal growth factor receptor for patients with newly diagnosed metastatic colorectal cancer. PMID: 18361803 Ref: The future of anti-EGFR therapy. PMID: 28207119 |
Ref: Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer. PMID: 18349392 Ref: Persisting corneal erosion under cetuximab (Erbitux) treatment (epidermal growth factor receptor antibody). PMID: 18520515 Ref: (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells. PMID: 18586691 Ref: Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines. PMID: 18691415 Ref: Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. PMID: 19010858 |
Ref: [Synergistic use of epidermal growth factor and 5-fluorouracil for the treatment of human colorectal cancer in BALB/C nude mice subcutaneous xenograft model]. PMID: 19145509 Ref: Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines. PMID: 19331154 Ref: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling. PMID: 19343194 Ref: Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells. PMID: 19492417 Ref: Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers. PMID: 19585504 Ref: [Expression and clinical significance of metastasis-related tumor markers in colorectal cancer]. PMID: 19728913 Ref: Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2. PMID: 19781065 Ref: Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells. PMID: 19846936 Ref: The EGF 61A/G polymorphism - a predictive marker for recurrence of liver metastases from colorectal cancer. PMID: 19921131 |
Ref: Antiproliferative/cytotoxic activity of molecular iodine and iodolactones in various human carcinoma cell lines. No interfering with EGF-signaling, but evidence for apoptosis. PMID: 19802778 Ref: Rho-kinase regulates negatively the epidermal growth factor-stimulated colon cancer cell proliferation. PMID: 20126978 Ref: (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells. PMID: 20346928 Ref: Multimodality therapy for adenocarcinoma of the esophagus, gastric cardia, and upper gastric third. PMID: 20676879 Ref: Reduction of G0 phase cells of colon cancer caco-2 cells may enhance 5-fluorouracil efficacy. PMID: 23554613 |
Ref: Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. PMID: 21273532 Ref: Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. PMID: 21317303 Ref: Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells. PMID: 21369697 Ref: Changes in growth factor levels after thermal ablation in a murine model of colorectal liver metastases. PMID: 21418130 Ref: Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity. PMID: 21639915 Ref: Inhibition of aldose reductase prevents colon cancer metastasis. PMID: 21642355 Ref: Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells. PMID: 21961726 Ref: Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer. PMID: 22117530 Ref: Evaluation of endostatin and EGF serum levels in patients with gastric cancer. PMID: 22166241 Ref: The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer. PMID: 24213116 |
Ref: Effect of rs6983267 polymorphism in the 8q24 region and rs4444903 polymorphism in EGF gene on the risk of sporadic colorectal cancer in Iranian population. PMID: 21567271 Ref: Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells. PMID: 21882253 Ref: Meta-analysis of epidermal growth factor polymorphisms and cancer risk: involving 9,779 cases and 15,932 controls. PMID: 22070650 Ref: Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells. PMID: 22266356 Ref: Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array. PMID: 22363134 Ref: Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition. PMID: 22547830 Ref: Association of epidermal growth factor +61 A/G polymorphism in Chinese patients with colon cancer. PMID: 22621366 Ref: Amphiregulin is a prognostic factor in colorectal cancer. PMID: 22641668 Ref: Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway. PMID: 22685297 Ref: Epidermal growth factor (EGF) regulates alpha5beta1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A. PMID: 23007402 Ref: Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel. PMID: 23213241 |
Ref: Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab. PMID: 22956286 Ref: EGF +61A>G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis. PMID: 23403233 Ref: Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cells. PMID: 23420529 Ref: Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors. PMID: 23638973 Ref: Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling. PMID: 24069372 Ref: Correlation between the EGF gene intronic polymorphism, rs2298979, and colorectal cancer. PMID: 24137467 Ref: Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer. PMID: 24180698 Ref: The effect of 5'untranslated region polymorphism in EGF gene, rs4444903, on colorectal cancer. PMID: 24834259 Ref: Different frequency of epidermal growth factor rs76189946 polymorphism genotype in an Iranian colorectal cancer. PMID: 24834285 |
Ref: The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. PMID: 23625650 Ref: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity. PMID: 23644655 Ref: COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-alpha. PMID: 24692712 Ref: EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules. PMID: 24792576 Ref: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase. PMID: 24890449 Ref: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells. PMID: 24893630 Ref: Effect of Yiqi Jianpi plus anticancer herbs on spleen deficiency in colorectal cancer and its anti-tumor role. PMID: 25063064 Ref: Association between EGF and VEGF functional polymorphisms and sporadic colorectal cancer in the Malaysian population. PMID: 25117311 Ref: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells. PMID: 25122478 Ref: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow. PMID: 25242215 |
Ref: SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer. PMID: 25804623 Ref: Sequential cancer mutations in cultured human intestinal stem cells. PMID: 25924068 |
Ref: The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer. PMID: 26522728 Ref: Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES. PMID: 26627827 Ref: NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells. PMID: 26781991 Ref: Biphasic activation of extracellular signal-regulated kinase (ERK) 1/2 in epidermal growth factor (EGF)-stimulated SW480 colorectal cancer cells. PMID: 26879318 Ref: Predictive Value of Growth Factors and Interleukins for Future Liver Remnant Volume and Colorectal Liver Metastasis Volume Growth Following Portal Vein Embolization and Autologous Stem Cell Application. PMID: 27069178 Ref: Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation. PMID: 27369075 Ref: Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance). PMID: 27465221 Ref: Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer. PMID: 27721235 |
Ref: SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer. PMID: 28088387 Ref: Ezrin/NF-kB activation regulates epithelial- mesenchymal transition induced by EGF and promotes metastasis of colorectal cancer. PMID: 28535417 Ref: Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death. PMID: 28823963 |
Ref: Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration. PMID: 29086459 Ref: LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity. PMID: 29149105 Ref: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer. PMID: 29361822 Ref: Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation. PMID: 29374558 Ref: Epidermal growth factor-mediated Rab25 pathway regulates integrin beta1 trafficking in colon cancer. PMID: 29515334 Ref: An improved method for culturing patient-derived colorectal cancer spheroids. PMID: 29774115 Ref: STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening. PMID: 30068339 Ref: EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFRpositive cancer cells. PMID: 30226622 Ref: Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer. PMID: 30360391 |