Primary Site >> Colorectal Cancer

Gene >> EDN1

Journal: Cancer Res. 1990 Jun 1;50(11):3257-61.
Title: Production of endothelin in human cancer cell lines.
Author: Kusuhara, M|Yamaguchi, K|Nagasaki, K|Hayashi, C|Suzaki, A|Hori, S|Handa, S|Nakamura, Y|Abe, K
PMID: 2185884
Journal: J Pathol. 1992 Nov;168(3):263-7.
Title: Autoradiographic localization of endothelin-1 binding sites in human colonic cancer tissue.
Author: Inagaki, H|Bishop, A E|Eimoto, T|Polak, J M
PMID: 1469505
Journal: Br J Surg. 1998 Apr;85(4):502-6.
Title: Raised endothelin 1 levels in patients with colorectal liver metastases.
Author: Shankar, A|Loizidou, M|Aliev, G|Fredericks, S|Holt, D|Boulos, P B|Burnstock, G|Taylor, I
PMID: 9607532
Journal: Int J Cancer. 2000 Apr 15;86(2):182-7.
Title: Endothelin receptor blockade potentiates FasL-induced apoptosis in rat colon carcinoma cells.
Author: Eberl, L P|Valdenaire, O|Saintgiorgio, V|Jeannin, J F|Juillerat-Jeanneret, L
PMID: 10738244
Journal: Gut. 2000 Nov;47(5):685-8.
Title: Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists.
Author: Ali, H|Loizidou, M|Dashwood, M|Savage, F|Sheard, C|Taylor, I
PMID: 11034585
Journal: J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S354-6.
Title: Endothelin receptor blockade potentiates FasL-induced apoptosis in colon carcinoma cells via the protein kinase C-pathway.
Author: Eberl, L P|Egidy, G|Pinet, F|Juillerat-Jeanneret, L
PMID: 11078419
Journal: Am J Pathol. 2000 Dec;157(6):1863-74.
Title: Modulation of human colon tumor-stromal interactions by the endothelin system.
Author: Egidy, G|Juillerat-Jeanneret, L|Jeannin, J F|Korth, P|Bosman, F T|Pinet, F
PMID: 11106559
Journal: Int J Biol Markers. 2000 Oct-Dec;15(4):288-93.
Title: Elevated serum endothelin-1 levels in patients with colorectal cancer; relevance for prognosis.
Author: Peeters, C F|Thomas, C M|Sweep, F C|Span, P N|Wobbes, T|Ruers, T M
PMID: 11192823
Journal: J Biol Regul Homeost Agents. 2001 Apr-Jun;15(2):140-4.
Title: Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1.
Author: Lissoni, P|Malugani, F|Bonfanti, A|Bucovec, R|Secondino, S|Brivio, F|Ferrari-Bravo, A|Ferrante, R|Vigore, L|Rovelli, F|Mandala, M|Viviani, S|Fumagalli, L|Gardani, G S
PMID: 11501971
Journal: Int J Dermatol. 2001 Nov;40(11):704-8.
Title: Nitric oxide and endothelin-1,2 in actinic keratosis and basal cell carcinoma: changes in nitric oxide/endothelin ratio.
Author: Vural, P|Erzengin, D|Canbaz, M|Selcuki, D
PMID: 11737437
Journal: Br J Cancer. 2001 Nov 30;85(11):1759-63.
Title: Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET(A) receptor antagonism.
Author: Asham, E|Shankar, A|Loizidou, M|Fredericks, S|Miller, K|Boulos, P B|Burnstock, G|Taylor, I
PMID: 11742499
Journal: Int J Biol Markers. 2002 Oct-Dec;17(4):268-74.
Title: The role of big endothelin-1 in colorectal cancer.
Author: Arun, C|Swift, B|Porter, K E|West, K P|London, N J M|Hemingway, D M
PMID: 12521131
Journal: Br J Cancer. 2003 Mar 10;88(5):788-95.
Title: Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells.
Author: Peduto Eberl, L|Bovey, R|Juillerat-Jeanneret, L
PMID: 12618891
Journal: Asian J Surg. 2004 Jan;27(1):4-9.
Title: Prognosis of colorectal cancer patients with elevated endothelin-1 concentrations.
Author: Elahi, Maqsood M|Everson, Noel W
PMID: 14717137
Journal: Mol Carcinog. 2004 Apr;39(4):221-33.
Title: The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells.
Author: Ignatenko, Natalia A|Zhang, Hui|Watts, George S|Skovan, Bethany A|Stringer, David E|Gerner, Eugene W
PMID: 15057874
Journal: Int J Biol Markers. 2004 Jan-Mar;19(1):32-7.
Title: Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer.
Author: Arun, C|London, N J M|Hemingway, D M
PMID: 15077924
Journal: J Gene Med. 2005 Mar;7(3):263-75.
Title: In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy.
Author: Mavria, Georgia|Harrington, Kevin J|Marshall, Christopher J|Porter, Colin D
PMID: 15543524
Journal: Oncogene. 2005 Jan 20;24(4):597-604.
Title: beta-Catenin activates the growth factor endothelin-1 in colon cancer cells.
Author: Kim, Tae Hoon|Xiong, Hui|Zhang, Zhuohua|Ren, Bing
PMID: 15558022
Journal: Endocr Relat Cancer. 2005 Dec;12(4):761-72.
Title: Emerging role of the endothelin axis in ovarian tumor progression.
Author: Bagnato, Anna|Spinella, Francesca|Rosano, Laura
PMID: 16322321
Journal: Mol Pharmacol. 2006 Feb;69(2):520-31.
Title: Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells.
Author: Sun, Ping|Xiong, Hui|Kim, Tae Hoon|Ren, Bing|Zhang, Zhuohua
PMID: 16291872
Journal: Eur J Gastroenterol Hepatol. 2007 Sep;19(9):775-82.
Title: Altered endothelin receptor subtypes in colorectal cancer.
Author: Hoosein, Moinuddin M|Dashwood, Michael R|Dawas, Khaled|Ali, Haythem M M D A|Grant, Katherine|Savage, Felicity|Taylor, Irving|Loizidou, Marilena
PMID: 17700263
Journal: J Cancer Res Clin Oncol. 2007 Oct;133(10):749-59. Epub 2007 May 25.
Title: Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression.
Author: Alldinger, I|Schaefer, K L|Goedde, D|Ottaviano, L|Dirksen, U|Ranft, A|Juergens, H|Gabbert, H E|Knoefel, W T|Poremba, C
PMID: 17530287
Journal: Br J Surg. 2007 Jan;94(1):106-12.
Title: Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines.
Author: Grant, K|Knowles, J|Dawas, K|Burnstock, G|Taylor, I|Loizidou, M
PMID: 17078114
Journal: Mol Cancer Ther. 2007 Apr;6(4):1433-9.
Title: 1alpha,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells.
Author: Ben-Shoshan, Moshe|Amir, Sharon|Dang, Duyen T|Dang, Long H|Weisman, Yosef|Mabjeesh, Nicola J
PMID: 17431122
Journal: Rev Esp Enferm Dig. 2008 Jun;100(6):327-31.
Title: [Effect of endothelin-1 on tumor arteries in patients with colorectal cancer].
Author: Ferrero Herrero, E|Garcia Villalon, A L|Labalde Martinez, M|Dieguez Castrillo, G|Hidalgo Pascual, M
PMID: 18752360
Journal: J Egypt Natl Canc Inst. 2008 Sep;20(3):216-23.
Title: Study of endothelin-1 and vascular endothelial growth factor in patients with cancer colon.
Author: Abdel-Gawad, Iman A|Hassanein, Hala M R|Bahgat, Nahla A|Abdel Sattar, Mona A|El-Sissy, Azza H|Altaweel, Maha A|Helal, Amany M
PMID: 20424651
Journal: Int J Oncol. 2009 May;34(5):1281-9.
Title: Identification of proteins associated to multi-drug resistance in LoVo human colon cancer cells.
Author: Visentin, Michele|Simula, Maria Paola|Sartor, Franca|Petrucco, Alessandra|De Re, Valli|Toffoli, Giuseppe
PMID: 19360340
Journal: Cancer Res. 2009 May 15;69(10):4260-9.
Title: Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells.
Author: Ghoul, Aida|Serova, Maria|Astorgues-Xerri, Lucile|Bieche, Ivan|Bousquet, Guilhem|Varna, Mariana|Vidaud, Michel|Phillips, Edelmira|Weill, Sophie|Benhadji, Karim A|Lokiec, Francois|Cvitkovic, Esteban|Faivre, Sandrine|Raymond, Eric
PMID: 19417139
Journal: Colorectal Dis. 2011 Mar;13(3):290-5.
Title: The prognostic value of circulating big endothelin-1 in patients undergoing potentially curative resection for colorectal cancer.
Author: Lloyd, G M|Neal, C P|Arun, C|London, N J M|Hemingway, D M
PMID: 19906052
Journal: Eur Surg Res. 2011;47(1):45-51.
Title: Intraperitoneal administration of bevacizumab intraoperatively does not affect abdominal wound healing in rats.
Author: Pavlidis, E T|Ballas, K D|Psarras, K|Symeonidis, N G|Koliakos, G|Kouzi-Koliakos, K|Rafailidis, S F|Pavlidis, T E|Marakis, G N|Sakantamis, A K
PMID: 21606651
Journal: J Pathol. 2011 Oct;225(2):305-14.
Title: Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells.
Author: Puglisi, Maria Ausiliatrice|Barba, Marta|Corbi, Maddalena|Errico, Maria Federica|Giorda, Ezio|Saulnier, Nathalie|Boninsegna, Alma|Piscaglia, Anna Chiara|Carsetti, Rita|Cittadini, Achille|Gasbarrini, Antonio|Sgambato, Alessandro
PMID: 21826669
Journal: Int J Cancer. 2012 Mar 15;130(6):1264-72.
Title: Endothelin-1 stimulates colon cancer adjacent fibroblasts.
Author: Knowles, Jonathan P|Shi-Wen, Xu|Haque, Samer-ul|Bhalla, Ashish|Dashwood, Michael R|Yang, Shiyu|Taylor, Irving|Winslet, Marc C|Abraham, David J|Loizidou, Marilena
PMID: 21445967
Journal: J Surg Oncol. 2012 Jun 1;105(7):643-9.
Title: Expression patterns of endothelin-1 and its receptors in colorectal cancer.
Author: Liakou, Paraskevi|Tepetes, Kostantinos|Germenis, Anastasios|Leventaki, Vasiliki|Atsaves, Vassilis|Patsouris, Efstratios|Roidis, Nikolaos|Hatzitheophilou, Konstantinos|Rassidakis, George Z
PMID: 22213082
Journal: Oncogene. 2013 Sep 12;32(37):4343-54.
Title: Mesenchymal stem cells promote growth and angiogenesis of tumors in mice.
Author: Huang, W-H|Chang, M-C|Tsai, K-S|Hung, M-C|Chen, H-L|Hung, S-C
PMID: 23085755
Journal: Mol Cancer Ther. 2013 Aug;12(8):1556-67.
Title: Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: a preclinical study.
Author: Haque, Samer-ul|Dashwood, Michael R|Heetun, Mohammed|Shiwen, Xu|Farooqui, Noreen|Ramesh, Bala|Welch, Hazel|Savage, Felicity J|Ogunbiyi, Olagunju|Abraham, David J|Loizidou, Marilena
PMID: 23723122
Journal: Int J Cancer. 2013 Mar 1;132(5):1004-12.
Title: Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
Author: Wang, Rong|Lohr, Christiane V|Fischer, Kay|Dashwood, W Mohaiza|Greenwood, Jeffrey A|Ho, Emily|Williams, David E|Ashktorab, Hassan|Dashwood, Michael R|Dashwood, Roderick H
PMID: 22865632
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E85-91.
Title: Role of endothelin A receptor in colon cancer metastasis: in vitro and in vivo evidence.
Author: Nie, Shaolin|Zhou, Jumei|Bai, Fei|Jiang, Bonian|Chen, Juying|Zhou, Jianping
PMID: 23818293
Journal: J Pineal Res. 2014 May;56(4):415-26.
Title: Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-kappabeta.
Author: Leon, Josefa|Casado, Jorge|Jimenez Ruiz, Sergio M|Zurita, Maria Sol|Gonzalez-Puga, Cristina|Rejon, Juan D|Gila, Ana|Munoz de Rueda, Paloma|Pavon, Esther J|Reiter, Russel J|Ruiz-Extremera, Angela|Salmeron, Javier
PMID: 24628039
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2014 May;34(5):694-8.
Title: [Effects of different anesthesia depth on stress response in elderly patients undergoing elective laparoscopic surgery for colorectal cancer].
Author: Tian, Keyun|Kang, Yin|Deng, Longjiao|Liu, Hong|Li, Haifeng|Wang, Zhipeng|Zhao, Guodong
PMID: 24849439
Journal: Oncotarget. 2015 Dec 15;6(40):42749-60.
Title: Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability.
Author: Niechi, Ignacio|Silva, Eduardo|Cabello, Pablo|Huerta, Hernan|Carrasco, Valentina|Villar, Paulina|Cataldo, Luis Rodrigo|Marcelain, Katherine|Armisen, Ricardo|Varas-Godoy, Manuel|Fernandez, Cristina|Tapia, Julio C
PMID: 26543229
Journal: Tumour Biol. 2016 Jan;37(1):583-90.
Title: Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness.
Author: Klahan, Sukhontip|Huang, Chi-Cheng|Chien, Shu-Chen|Wu, Mei-Shin|Wong, Henry Sung-Ching|Huang, Chien-Yu|Chang, Wei-Chiao|Wei, Po-Li
PMID: 26232912
Journal: Int J Immunopathol Pharmacol. 2016 Jun;29(2):333-40.
Title: Epigenetic silencing of endothelin-3 in colorectal cancer.
Author: Olender, J|Nowakowska-Zajdel, E|Kruszniewska-Rajs, C|Orchel, J|Mazurek, U|Wierzgon, A|Kokot, T|Muc-Wierzgon, M
PMID: 26684626
Journal: Oncotarget. 2016 May 17;7(20):29187-98.
Title: Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer.
Author: Bhattacharya, Bhaskar|Low, Sarah Hong Hui|Chong, Mei Ling|Chia, Dilys|Koh, King Xin|Sapari, Nur Sabrina|Kaye, Stanley|Hung, Huynh|Benoukraf, Touati|Soong, Richie
PMID: 27081080
Journal: Cancer Res. 2017 May 1;77(9):2413-2423.
Title: Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ.
Author: Wang, Zhen|Liu, Peng|Zhou, Xin|Wang, Tianxiang|Feng, Xu|Sun, Yi-Ping|Xiong, Yue|Yuan, Hai-Xin|Guan, Kun-Liang
PMID: 28249901
Journal: Cell Death Differ. 2017 Oct;24(10):1811-1820.
Title: Blocking endothelin-1-receptor/beta-catenin circuit sensitizes to chemotherapy in colorectal cancer.
Author: Cianfrocca, Roberta|Rosano, Laura|Tocci, Piera|Sestito, Rosanna|Caprara, Valentina|Di Castro, Valeriana|De Maria, Ruggero|Bagnato, Anna
PMID: 28708138
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110