Primary Site >> Colorectal Cancer
Gene >> EDN1
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Ref: Production of endothelin in human cancer cell lines. PMID: 2185884 |
Ref: Autoradiographic localization of endothelin-1 binding sites in human colonic cancer tissue. PMID: 1469505 |
Ref: Raised endothelin 1 levels in patients with colorectal liver metastases. PMID: 9607532 |
Ref: Endothelin receptor blockade potentiates FasL-induced apoptosis in rat colon carcinoma cells. PMID: 10738244 Ref: Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists. PMID: 11034585 Ref: Endothelin receptor blockade potentiates FasL-induced apoptosis in colon carcinoma cells via the protein kinase C-pathway. PMID: 11078419 Ref: Modulation of human colon tumor-stromal interactions by the endothelin system. PMID: 11106559 Ref: Elevated serum endothelin-1 levels in patients with colorectal cancer; relevance for prognosis. PMID: 11192823 |
Ref: Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1. PMID: 11501971 Ref: Nitric oxide and endothelin-1,2 in actinic keratosis and basal cell carcinoma: changes in nitric oxide/endothelin ratio. PMID: 11737437 Ref: Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET(A) receptor antagonism. PMID: 11742499 |
Ref: The role of big endothelin-1 in colorectal cancer. PMID: 12521131 |
Ref: Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells. PMID: 12618891 |
Ref: Prognosis of colorectal cancer patients with elevated endothelin-1 concentrations. PMID: 14717137 Ref: The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells. PMID: 15057874 Ref: Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer. PMID: 15077924 |
Ref: In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy. PMID: 15543524 Ref: beta-Catenin activates the growth factor endothelin-1 in colon cancer cells. PMID: 15558022 Ref: Emerging role of the endothelin axis in ovarian tumor progression. PMID: 16322321 |
Ref: Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells. PMID: 16291872 |
Ref: Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines. PMID: 17078114 Ref: 1alpha,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells. PMID: 17431122 Ref: Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression. PMID: 17530287 Ref: Altered endothelin receptor subtypes in colorectal cancer. PMID: 17700263 |
Ref: [Effect of endothelin-1 on tumor arteries in patients with colorectal cancer]. PMID: 18752360 Ref: Study of endothelin-1 and vascular endothelial growth factor in patients with cancer colon. PMID: 20424651 |
Ref: Identification of proteins associated to multi-drug resistance in LoVo human colon cancer cells. PMID: 19360340 Ref: Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. PMID: 19417139 |
Ref: The prognostic value of circulating big endothelin-1 in patients undergoing potentially curative resection for colorectal cancer. PMID: 19906052 Ref: Intraperitoneal administration of bevacizumab intraoperatively does not affect abdominal wound healing in rats. PMID: 21606651 Ref: Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells. PMID: 21826669 |
Ref: Endothelin-1 stimulates colon cancer adjacent fibroblasts. PMID: 21445967 Ref: Expression patterns of endothelin-1 and its receptors in colorectal cancer. PMID: 22213082 |
Ref: Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer. PMID: 22865632 Ref: Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. PMID: 23085755 Ref: Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: a preclinical study. PMID: 23723122 |
Ref: Role of endothelin A receptor in colon cancer metastasis: in vitro and in vivo evidence. PMID: 23818293 Ref: Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-kappabeta. PMID: 24628039 Ref: [Effects of different anesthesia depth on stress response in elderly patients undergoing elective laparoscopic surgery for colorectal cancer]. PMID: 24849439 |
Ref: Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability. PMID: 26543229 |
Ref: Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness. PMID: 26232912 Ref: Epigenetic silencing of endothelin-3 in colorectal cancer. PMID: 26684626 Ref: Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer. PMID: 27081080 |
Ref: Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ. PMID: 28249901 Ref: Blocking endothelin-1-receptor/beta-catenin circuit sensitizes to chemotherapy in colorectal cancer. PMID: 28708138 |
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 |